3.4.24.B9: ADAM9 endopeptidase

This is an abbreviated version!
For detailed information about ADAM9 endopeptidase, go to the full flat file.

Reaction

proteolytic degradation of proteins =

Synonyms

a disintegrin and metalloproteinase domain 9, ADAM 9, ADAM metallopeptidase domain 9, ADAM-9, ADAM-9 sheddase, ADAM9, cellular disintegrin-related protein, M12.209, MDC, MDC-9, MDC9, MDC9/meltrin-gamma/ADAM9, meltrin gamma, meltrin-gamma, metallo protease desintegrin 9, metalloprotease ADAM9, metalloprotease disintegrin 9, metalloprotease/disintegrin/cysteine-rich protein 9, MLTNG, More, myeloma cell metalloproteinase

ECTree

     3 Hydrolases

         3.4 Acting on peptide bonds (peptidases)

             3.4.24 Metalloendopeptidases

                3.4.24.B9 ADAM9 endopeptidase

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Results	in table
6	Activating Compound
3	AA Sequence
12	Application
1	CAS Registry Number
15	Cloned(Commentary)
1199	Disease/ Diagnostics
1	Expression
15	General Information
5	IC50 Value
32	Inhibitors
9	Ki Value [mM]
14	Localization
5	Metals/Ions
12	Molecular Weight [Da]
24	Natural Substrates/ Products (Substrates)
44	Organism
2	pH Optimum
8	Posttranslational Modification
12	Protein Variants
4	Purification (Commentary)
1	Reaction
13	Reaction Type
44	Reference
84	Source Tissue
2	Specific Activity [micromol/min/mg]
49	Substrates and Products (Substrate)
8	Subunits
70	Synonyms
3	Temperature Optimum [°C]

IC50 Value

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IC50 Value on EC 3.4.24.B9 - ADAM9 endopeptidase

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IC50 VALUE [mM]

INHIBITOR

ORGANISM

UNIPROT

COMMENTARY

LITERATURE

IMAGE

0.00005

batimastat

Mus musculus

Q61072

pH not specified in the publication, temperature not specified in the publication

752720

0.00072

GM6001

Mus musculus

Q61072

pH not specified in the publication, temperature not specified in the publication

752720

0.00048

GW280264X

Mus musculus

Q61072

pH not specified in the publication, temperature not specified in the publication

752720

0.00013

marimastat

Mus musculus

Q61072

pH not specified in the publication, temperature not specified in the publication

752720

0.0135

TAPI-2

Mus musculus

Q61072

pH not specified in the publication, temperature not specified in the publication

752720