3.4.24.B9: ADAM9 endopeptidase
This is an abbreviated version!
For detailed information about ADAM9 endopeptidase, go to the full flat file.
Word Map on EC 3.4.24.B9
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3.4.24.B9
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adams
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metastasis
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ectodomains
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metalloproteases
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alpha-secretase
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hb-egf
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medicine
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adam-15
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non-amyloidogenic
- 3.4.24.B9
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adams
- metastasis
- ectodomains
- metalloproteases
- alpha-secretase
- hb-egf
- medicine
-
adam-15
-
non-amyloidogenic
Reaction
proteolytic degradation of proteins =
Synonyms
a disintegrin and metalloproteinase domain 9, ADAM 9, ADAM metallopeptidase domain 9, ADAM-9, ADAM-9 sheddase, ADAM9, cellular disintegrin-related protein, M12.209, MDC, MDC-9, MDC9, MDC9/meltrin-gamma/ADAM9, meltrin gamma, meltrin-gamma, metallo protease desintegrin 9, metalloprotease ADAM9, metalloprotease disintegrin 9, metalloprotease/disintegrin/cysteine-rich protein 9, MLTNG, More, myeloma cell metalloproteinase
ECTree
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Activating Compound
Activating Compound on EC 3.4.24.B9 - ADAM9 endopeptidase
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stanolone
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upregulation, 1.5fold increase in activity at 0.000001 mM, 1.7fold at 0.00001 mM
additional information
ADAM9 does not respond to stimulation with phorbol esters, calcium ionophore or phosphatase inhibitors
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binds to the enzyme at its cytoplasmic part and cooperates in cleavage of EGF-like growth factor
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Protein kinase C
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phosphorylation of the enzyme by protein kinase C activates the enzyme, phosphorylation is stimualted by phorbol 12-myristate 13-acetate
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