3.4.24.B9: ADAM9 endopeptidase
This is an abbreviated version!
For detailed information about ADAM9 endopeptidase, go to the full flat file.
Word Map on EC 3.4.24.B9
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3.4.24.B9
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adams
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metastasis
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ectodomains
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metalloproteases
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alpha-secretase
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hb-egf
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medicine
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adam-15
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non-amyloidogenic
- 3.4.24.B9
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adams
- metastasis
- ectodomains
- metalloproteases
- alpha-secretase
- hb-egf
- medicine
-
adam-15
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non-amyloidogenic
Reaction
proteolytic degradation of proteins =
Synonyms
a disintegrin and metalloproteinase domain 9, ADAM 9, ADAM metallopeptidase domain 9, ADAM-9, ADAM-9 sheddase, ADAM9, cellular disintegrin-related protein, M12.209, MDC, MDC-9, MDC9, MDC9/meltrin-gamma/ADAM9, meltrin gamma, meltrin-gamma, metallo protease desintegrin 9, metalloprotease ADAM9, metalloprotease disintegrin 9, metalloprotease/disintegrin/cysteine-rich protein 9, MLTNG, More, myeloma cell metalloproteinase
ECTree
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Inhibitors
Inhibitors on EC 3.4.24.B9 - ADAM9 endopeptidase
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brefeldin A
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blocks processing of the enzyme precursor by blocking the vesicle budding in the endoplasmic reticulum
Hydroxamates
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metalloprotease inhibitors, derivatives FN-439, BB3103, BB 3241, and IC-3
TIMP-3
i.e. tissue inhibitor of metalloproteinases-3, inhibition at 10 nM
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interaction of the enzyme with integrins is inhibited by antibodies against the alphaVbeta5-domain of integrin
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additional information
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no inhibition by the metalloprotease inhibitors TIMP-1, -2, and -4
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