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3.4.24.34: neutrophil collagenase

This is an abbreviated version!
For detailed information about neutrophil collagenase, go to the full flat file.

Word Map on EC 3.4.24.34

Reaction

Cleavage of interstitial collagens in the triple helical domain. Unlike EC 3.4.24.7, interstitial collagenase, this enzyme cleaves type III collagen additional information slowly than type I =

Synonyms

collagenase-2, collagenases-8, EC 3.4.24.7, HNC, human neutrophil collagenase, matrix metalloproteinase, Matrix metalloproteinase 8, Matrix metalloproteinase-8, metalloproteinase-8, MetMMP-8, MMP-7, MMP-8, MMP8, neutrophil collagenase, neutrophil collagenase MMP-8, neutrophil interstitial collagenase, PheMMP-8, PMNL collagenase, PMNL-CL, polymorphonuclear leukocyte collagenase, whMMP-8

ECTree

     3 Hydrolases
         3.4 Acting on peptide bonds (peptidases)
             3.4.24 Metalloendopeptidases
                3.4.24.34 neutrophil collagenase

Localization

Localization on EC 3.4.24.34 - neutrophil collagenase

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LOCALIZATION
ORGANISM
UNIPROT
COMMENTARY hide
GeneOntology No.
LITERATURE
SOURCE
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binding of MMP-8 to the surface of polymorphonuclear cells promotes stability
Manually annotated by BRENDA team
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membrane-bound MMP-8 is a more potent MIP-1alpha-degrading enzyme than soluble MMP-8
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Manually annotated by BRENDA team