3.4.22.53: calpain-2

This is an abbreviated version!
For detailed information about calpain-2, go to the full flat file.

Word Map on EC 3.4.22.53

3.4.22.53

calpains

calpastatin

mu-calpain

calcium-dependent

ca2+-dependent

proteinase

myofibrillar

cytoskeletal

cataract

zymography

longissimus

meat

autolysis

calpeptin

tender

casein

cathepsins

3.4.22.17

postmortem

calpain-mediated

caspase-12

lumborum

autolyzed

lens-specific

talin

alpha-spectrin

canps

cataractogenesis

warner-bratzler

spectrin

slaughter

semimembranosus

calpain-specific

desmin

calpain-calpastatin

lenses

calpain-dependent

atrogin-1

medicine

calpain-induced

fodrin

myofibril

ca2+-activated

calmodulin-like

caseinolytic

thoracis

ca2+-requiring

troponin-t

micro-calpain

calpain-like

proteolyzed

Reaction

broad endopeptidase specificity =

Synonyms

Cal II, calcium-activated neutral protease II, calpain 2, calpain II, calpain xCL-2 (Xenopus leavis), calpain-2, calpain-2-like, calpain2, CAPN II, CAPN2, CAPN2 g.p. (Homo sapiens), CPN2, cysteine protease, EC 3.4.22.17, EC 3.4.24.5, human calpain 2, m-calpain, milli-calpain, mitochondrial m-calpain, nCL-2, rat calpain 2

ECTree

3 Hydrolases

3.4 Acting on peptide bonds (peptidases)

3.4.22 Cysteine endopeptidases

3.4.22.53 calpain-2

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Results	in table
10	Activating Compound
1153	AA Sequence
4	Application
2	CAS Registry Number
15	Cloned(Commentary)
8	Crystallization (Commentary)
795	Disease/ Diagnostics
13	Expression
40	General Information
4	General Stability
6	IC50 Value
192	Inhibitors
8	kcat/KM [mM/s]
19	Ki Value [mM]
17	KM Value [mM]
32	Localization
77	Metals/Ions
53	Molecular Weight [Da]
64	Natural Substrates/ Products (Substrates)
144	Organism
1	Oxidation Stability
9	PDB ID
15	pH Optimum
6	pH Range
4	pH Stability
1	pI Value
4	Posttranslational Modification
35	Protein Variants
23	Purification (Commentary)
1	Reaction
2	Reaction Type
143	Reference
145	Source Tissue
12	Specific Activity [micromol/min/mg]
2	Storage Stability
165	Substrates and Products (Substrate)
28	Subunits
109	Synonyms
8	Temperature Optimum [°C]
2	Temperature Range [°C]
8	Temperature Stability [°C]
12	Turnover Number [1/s]

KCat KM Value

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KCat KM Value on EC 3.4.22.53 - calpain-2

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0.135 - 0.137

succinyl-Leu-Leu-Val-Tyr-7-amido-4-methylcoumarin

2 entries

0.0399 - 0.0404

succinyl-Leu-Met-7-amido-4-methylcoumarin

2 entries

0.0394 - 0.0395

succinyl-Leu-Tyr-7-amido-4-methylcoumarin

2 entries

0.131 - 0.133

t-butyloxycarbonyl-Val-Leu-Lys-7-amido-4-methylcoumarin

2 entries