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3.4.22.53: calpain-2

This is an abbreviated version!
For detailed information about calpain-2, go to the full flat file.

Word Map on EC 3.4.22.53

Reaction

broad endopeptidase specificity =

Synonyms

Cal II, calcium-activated neutral protease II, calpain 2, calpain II, calpain xCL-2 (Xenopus leavis), calpain-2, calpain-2-like, calpain2, CAPN II, CAPN2, CAPN2 g.p. (Homo sapiens), CPN2, cysteine protease, EC 3.4.22.17, EC 3.4.24.5, human calpain 2, m-calpain, milli-calpain, mitochondrial m-calpain, nCL-2, rat calpain 2

ECTree

     3 Hydrolases
         3.4 Acting on peptide bonds (peptidases)
             3.4.22 Cysteine endopeptidases
                3.4.22.53 calpain-2

Turnover Number

Turnover Number on EC 3.4.22.53 - calpain-2

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TURNOVER NUMBER [1/s]
SUBSTRATE
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
IMAGE
0.341
Boc-Val-Leu-Lys-methylcoumarin
-
pH 7.5, room temperature
0.062 - 0.063
succinyl-Leu-Leu-Val-Tyr-7-amido-4-methylcoumarin
0.0394
succinyl-Leu-Leu-Val-Tyr-methylcoumarin
-
pH 7.5, room temperature
0.186 - 0.189
succinyl-Leu-Met-7-amido-4-methylcoumarin
0.04 - 0.084
succinyl-Leu-Tyr-7-amido-4-methylcoumarin
0.546
t-Boc-Leu-Met-methylcoumarin
-
-
1.06 - 1.08
t-butyloxycarbonyl-Val-Leu-Lys-7-amido-4-methylcoumarin