3.4.21.117: stratum corneum chymotryptic enzyme

This is an abbreviated version!
For detailed information about stratum corneum chymotryptic enzyme, go to the full flat file.

Reaction

cleavage of proteins with aromatic side chains in the P1 position =

Synonyms

hK7, HSCCE, human stratum corneum chymotryptic enzyme, K7, kallikrein 7, kallikrein-7, kallikrein-related peptidase, kallikrein-related peptidase 7, KLK7, More, S01.300, SCCE, stratum corneum chymotryptic enzyme, tissue kallikrein, tissue kallikrein 7

ECTree

     3 Hydrolases

         3.4 Acting on peptide bonds (peptidases)

             3.4.21 Serine endopeptidases

                3.4.21.117 stratum corneum chymotryptic enzyme

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Results	in table
6	Activating Compound
2	AA Sequence
16	Application
2	CAS Registry Number
25	Cloned(Commentary)
7	Crystallization (Commentary)
286	Disease/ Diagnostics
2	Expression
14	General Information
17	IC50 Value
100	Inhibitors
27	kcat/KM [mM/s]
30	Ki Value [mM]
38	KM Value [mM]
6	Localization
7	Metals/Ions
4	Molecular Weight [Da]
32	Natural Substrates/ Products (Substrates)
69	Organism
41	PDB ID
15	pH Optimum
1	pH Range
9	Posttranslational Modification
9	Protein Variants
10	Purification (Commentary)
11	Reaction
1	Reaction Type
68	Reference
1	Renatured (Commentary)
174	Source Tissue
4	Specific Activity [micromol/min/mg]
183	Substrates and Products (Substrate)
7	Subunits
103	Synonyms
13	Temperature Optimum [°C]
36	Turnover Number [1/s]

Sequence

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Sequence on EC 3.4.21.117 - stratum corneum chymotryptic enzyme

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UNIPROT

ENTRY NAME

ORGANISM

NO. OF AA

NO. OF TRANSM. HELICES

MOLECULAR WEIGHT[Da]

SOURCE

SEQUENCE

LOCALIZATION PREDICTIONThe reliability class of the localization prediction ranges from 1 (very reliable) to 5 (not reliable).

P49862 pBLAST

KLK7_HUMAN

Homo sapiens

253

0

27525

Swiss-Prot

Show Sequence

Secretory Pathway (Reliability: 1)

Q91VE3 pBLAST

KLK7_MOUSE

Mus musculus

249

0

27257

Swiss-Prot

Show Sequence

Secretory Pathway (Reliability: 1)

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