3.4.21.117: stratum corneum chymotryptic enzyme
This is an abbreviated version!
For detailed information about stratum corneum chymotryptic enzyme, go to the full flat file.
Word Map on EC 3.4.21.117
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3.4.21.117
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klk7
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desquamation
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keratinocytes
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cornified
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corneocyte
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netherton
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corneodesmosomes
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desmogleins
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corneodesmosin
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spink5
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medicine
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desmocollin
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vaspin
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diagnostics
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molecular biology
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desquamatory
- 3.4.21.117
- klk7
-
desquamation
- keratinocytes
-
cornified
- corneocyte
- netherton
-
corneodesmosomes
-
desmogleins
- corneodesmosin
-
spink5
- medicine
-
desmocollin
- vaspin
- diagnostics
- molecular biology
-
desquamatory
Reaction
cleavage of proteins with aromatic side chains in the P1 position =
Synonyms
hK7, HSCCE, human stratum corneum chymotryptic enzyme, K7, kallikrein 7, kallikrein-7, kallikrein-related peptidase, kallikrein-related peptidase 7, KLK7, More, S01.300, SCCE, stratum corneum chymotryptic enzyme, tissue kallikrein, tissue kallikrein 7
ECTree
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KM Value
KM Value on EC 3.4.21.117 - stratum corneum chymotryptic enzyme
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0.002
Abz-GFSPFRSSRI-Q-N-[2,4-dinitrophenyl]-ethylenediamine
pH 7.5, 37°C
0.069
Abz-GFSPFRSSRIGEIKEETT-Q-N-[2,4-dinitrophenyl]-ethylenediamine
pH 7.5, 37°C
0.0059
Ac-ED(5-[(2-aminoethyl)amino]naphthalene-1-sulfonic acid)KPILFRLGK(4-(4-dimethylaminophenylazo)benzoic acid)E-NH2
kcat/KM: 170000/Msec
0.048
Ac-EFKPILWRLGC-(6-(9-oxo-9H-acridin-10-yl)-hexanoate)E-NH2
Vmax: 12 nM/sec
0.0443
L-Phe-7-amido-4-methylcoumarin
in 50 mM HEPES, pH 7.5, 150 mM NaCl, 0.005% Tween 20, at 25°C
0.0402
L-Tyr-7-amido-4-methylcoumarin
in 50 mM HEPES, pH 7.5, 150 mM NaCl, 0.005% Tween 20, at 25°C
0.304
wild-type, pH 8.0, temperature not specified in the publication
0.43
methoxy-succinyl-Arg-Pro-Tyr-7-amido-4-methylcoumarin
mutant S195A, pH 8.0, temperature not specified in the publication