3.4.17.11: glutamate carboxypeptidase

This is an abbreviated version!
For detailed information about glutamate carboxypeptidase, go to the full flat file.

Reaction

release of C-terminal glutamate residues from a wide range of N-acylating moieties, including peptidyl, aminoacyl, benzoyl, benzyloxycarbonyl, folyl and pteroyl groups =

Synonyms

carboxypeptidase G, carboxypeptidase G1, carboxypeptidase G2, CPDG2, CPG2, folate hydrolase G2, glucarpidase, glutamate carboxypeptidase, glutamyl carboxypeptidase, N-pteroyl-L-glutamate hydrolase, pteroylmonoglutamic acid hydrolase G2

ECTree

     3 Hydrolases

         3.4 Acting on peptide bonds (peptidases)

             3.4.17 Metallocarboxypeptidases

                3.4.17.11 glutamate carboxypeptidase

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Results	in table
1463	AA Sequence
17	Application
3	CAS Registry Number
7	Cloned(Commentary)
3	Crystallization (Commentary)
273	Disease/ Diagnostics
2	General Stability
2	IC50 Value
33	Inhibitors
27	KM Value [mM]
1	Localization
15	Metals/Ions
9	Molecular Weight [Da]
21	Natural Substrates/ Products (Substrates)
26	Organism
20	PDB ID
10	pH Optimum
1	pH Range
1	Posttranslational Modification
11	Protein Variants
11	Purification (Commentary)
1	Reaction
3	Reaction Type
26	Reference
1	Renatured (Commentary)
10	Source Tissue
6	Specific Activity [micromol/min/mg]
4	Storage Stability
98	Substrates and Products (Substrate)
5	Subunits
45	Synonyms
5	Temperature Optimum [°C]
1	Temperature Range [°C]
12	Temperature Stability [°C]
15	Turnover Number [1/s]

Storage Stability

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Storage Stability on EC 3.4.17.11 - glutamate carboxypeptidase

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STORAGE STABILITY

ORGANISM

UNIPROT

LITERATURE

-196°C, stable for several months

Pseudomonas sp.

-

647245

-20°C, 0.01 M Tris-chloride buffer, pH 7.3, 0.01 mM ZnCl2, stable for several months

Pseudomonas stutzeri

-

647244

-20°C, stable for 1 year

Flavobacterium sp.

-

647246

4°C, 0.01 M Tris-chloride buffer, pH 7.3, 0.01 mM ZnCl2, stable for 2 to 3 weeks

Pseudomonas stutzeri

-

647244