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3.4.17.11: glutamate carboxypeptidase

This is an abbreviated version!
For detailed information about glutamate carboxypeptidase, go to the full flat file.

Word Map on EC 3.4.17.11

Reaction

release of C-terminal glutamate residues from a wide range of N-acylating moieties, including peptidyl, aminoacyl, benzoyl, benzyloxycarbonyl, folyl and pteroyl groups =

Synonyms

carboxypeptidase G, carboxypeptidase G1, carboxypeptidase G2, CPDG2, CPG2, folate hydrolase G2, glucarpidase, glutamate carboxypeptidase, glutamyl carboxypeptidase, N-pteroyl-L-glutamate hydrolase, pteroylmonoglutamic acid hydrolase G2

ECTree

     3 Hydrolases
         3.4 Acting on peptide bonds (peptidases)
             3.4.17 Metallocarboxypeptidases
                3.4.17.11 glutamate carboxypeptidase

Temperature Stability

Temperature Stability on EC 3.4.17.11 - glutamate carboxypeptidase

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TEMPERATURE STABILITY
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
25
-
half-life: 90 min
28.2
melting temperature of mutant enzyme H112A
37
-
half-life: 45 min
4
-
half-life: 4 h
53.2
melting temperature of mutant enzyme D141A
53.4
melting temperature of mutant enzyme K208A
54.4
melting temperature of mutant enzyme S210A
55.1
melting temperature of mutant enzyme H385A
55.4
melting temperature of mutant enzyme T357A
60.4
melting temperature of wild-type enzyme
64.3
melting temperature of mutant enzyme E200A
71.4
melting temperature of mutant enzyme E175A