3.4.14.4: dipeptidyl-peptidase III
This is an abbreviated version!
For detailed information about dipeptidyl-peptidase III, go to the full flat file.
Word Map on EC 3.4.14.4
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3.4.14.4
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exopeptidase
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tynorphin
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enkephalin-degrading
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leu-enkephalin
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nudix
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spinorphin
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hexxh
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map2k5
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medicine
- 3.4.14.4
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exopeptidase
- tynorphin
-
enkephalin-degrading
- leu-enkephalin
-
nudix
- spinorphin
-
hexxh
-
map2k5
- medicine
Reaction
release of an N-terminal dipeptide from a peptide comprising four or additional information residues, with broad specificity. Also acts on dipeptidyl 2-naphthylamides. =
Synonyms
BT_1846, Cabys_2252, dipeptdiyl peptidase III, dipeptidyl aminopeptidase III, dipeptidyl arylamidase III, dipeptidyl peptidase III, dipeptidyl-peptidase III, dipeptidyl-peptide hydrolase, dipeptidylpeptidase III, DPP III, DPP-3, DPP-III, DPP3, DPPIII, enkephalinase B, NUDT3, peptidase, dipeptidyl, III, PG_0317, PHYPA_007037, red cell angiotensinase
ECTree
3.4.14.4 dipeptidyl-peptidase IIIAdvanced search results
results (
results (KI Value
KI Value on EC 3.4.14.4 - dipeptidyl-peptidase III
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Ki VALUE [mM] 
INHIBITOR
ORGANISM
UNIPROT
COMMENTARY 
LITERATURE
IMAGE
0.0002
1,3-di-[5-(2-imidazolinyl)-2-benzimidazolyl]-2,4-di-phenyl-cyclobutane dihydrochloride
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0.015
Gly-L-Phe-L-Leu
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in 50 mM Tris-HCl, pH 8.5, with 100 mM NaCl and 1 mM beta-mercaptoethanol, at 37°C
0.004
L-Arg-L-Phe-L-Ala
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in 50 mM Tris-HCl, pH 8.5, with 100 mM NaCl and 1 mM beta-mercaptoethanol, at 37°C
0.039
L-Leu-L-Trp
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in 50 mM Tris-HCl, pH 8.5, with 100 mM NaCl and 1 mM beta-mercaptoethanol, at 37°C
0.031
L-Leu-L-Trp-L-Met
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in 50 mM Tris-HCl, pH 8.5, with 100 mM NaCl and 1 mM beta-mercaptoethanol, at 37°C
0.007
L-Leu-L-Trp-L-Met-L-Arg-L-Phe-L-Ala
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in 50 mM Tris-HCl, pH 8.5, with 100 mM NaCl and 1 mM beta-mercaptoethanol, at 37°C
0.38
L-Trp-L-Met
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in 50 mM Tris-HCl, pH 8.5, with 100 mM NaCl and 1 mM beta-mercaptoethanol, at 37°C
0.055
L-tryptophyl-L-methionyl-L-alpha-aspartyl-L-phenylalaninamide
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in 50 mM Tris-HCl, pH 8.5, with 100 mM NaCl and 1 mM beta-mercaptoethanol, at 37°C
0.25
L-Val-L-Tyr
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in 50 mM Tris-HCl, pH 8.5, with 100 mM NaCl and 1 mM beta-mercaptoethanol, at 37°C
0.09
Leu-enkephalin
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in 50 mM Tris-HCl, pH 8.5, with 100 mM NaCl and 1 mM beta-mercaptoethanol, at 37°C
0.13
Met-enkephalin
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in 50 mM Tris-HCl, pH 8.5, with 100 mM NaCl and 1 mM beta-mercaptoethanol, at 37°C
0.00015
L-tyrosyl-L-phenylalanine hydroxamic acid
wild-type, pH 8.0, 37°C
0.00092
L-tyrosyl-L-phenylalanine hydroxamic acid
mutant W300F, pH 8.0, 37°C
0.00427
L-tyrosyl-L-phenylalanine hydroxamic acid
mutant W300L, pH 8.0, 37°C
