3.4.14.4: dipeptidyl-peptidase III

This is an abbreviated version!
For detailed information about dipeptidyl-peptidase III, go to the full flat file.

Reaction

release of an N-terminal dipeptide from a peptide comprising four or additional information residues, with broad specificity. Also acts on dipeptidyl 2-naphthylamides. =

Synonyms

BT_1846, Cabys_2252, dipeptdiyl peptidase III, dipeptidyl aminopeptidase III, dipeptidyl arylamidase III, dipeptidyl peptidase III, dipeptidyl-peptidase III, dipeptidyl-peptide hydrolase, dipeptidylpeptidase III, DPP III, DPP-3, DPP-III, DPP3, DPPIII, enkephalinase B, NUDT3, peptidase, dipeptidyl, III, PG_0317, PHYPA_007037, red cell angiotensinase

ECTree

     3 Hydrolases

         3.4 Acting on peptide bonds (peptidases)

             3.4.14 Dipeptidyl-peptidases and tripeptidyl-peptidases

                3.4.14.4 dipeptidyl-peptidase III

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Results	in table
2	Activating Compound
2426	AA Sequence
3	Application
1	CAS Registry Number
13	Cloned(Commentary)
9	Crystallization (Commentary)
83	Disease/ Diagnostics
1	Expression
2	General Information
2	General Stability
27	IC50 Value
274	Inhibitors
40	kcat/KM [mM/s]
60	Ki Value [mM]
65	KM Value [mM]
24	Localization
32	Metals/Ions
29	Molecular Weight [Da]
2	Organic Solvent Stability
148	Organism
22	PDB ID
33	pH Optimum
6	pH Range
4	pH Stability
4	pI Value
1	Posttranslational Modification
41	Protein Variants
31	Purification (Commentary)
1	Reaction
9	Reaction Type
77	Reference
1	Renatured (Commentary)
54	Source Tissue
30	Specific Activity [micromol/min/mg]
5	Storage Stability
160	Substrates and Products (Substrate)
22	Subunits
57	Synonyms
12	Temperature Optimum [°C]
3	Temperature Range [°C]
13	Temperature Stability [°C]
51	Turnover Number [1/s]

Storage Stability

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Storage Stability on EC 3.4.14.4 - dipeptidyl-peptidase III

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STORAGE STABILITY

ORGANISM

UNIPROT

LITERATURE

-10°C, 50 mM sodium phosphate buffer, pH 6.8, 1 mM mercaptoethanol, 0.5 M NaCl, 40% glycerol, 1 year

Homo sapiens

-

36178

-20°C, 50% glycerol, 1 year

Homo sapiens

-

36186

-20°C, in 50 mM Tris-HCl, pH 7.5, 1 and 6 months, 38.15% and 99.75% loss of activity

Capra hircus

-

699225

-20°C, in 50 mM Tris-HCl, pH 7.5, in the presence of 10% (v/v) glycerol, 1 and 6 months, 26.5% and 92% loss of activity

Capra hircus

-

699225

-80°C

Homo sapiens

-

36181