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1.14.19.17: sphingolipid 4-desaturase

This is an abbreviated version!
For detailed information about sphingolipid 4-desaturase, go to the full flat file.

Word Map on EC 1.14.19.17

Reaction

a dihydroceramide
+ 2 ferrocytochrome b5 +
O2
+ 2 H+ =
a (4E)-sphing-4-enine ceramide
+ 2 ferricytochrome b5 + 2 H2O

Synonyms

degenerative spermatocyte desaturase, DegS, Degs1, DEGS2, dehydroceramide desaturase, DELTA4 desaturase, DELTA4DES, DES-1, DES1, DES2, DHCD, dihydroceramide C4-desaturase, dihydroceramide DELTA4-(E)-desaturase, dihydroceramide DELTA4-desaturase, dihydroceramide DELTA4-desaturase 1, dihydroceramide desaturase, dihydroceramide desaturase 1, dihydroceramide desaturase 2, dihydroceramide desaturase-1, dihydroceramide-desaturase-1, drosophila degenerative spermatocyte 1, drosophila degenerative spermatocyte 2, ifc, LCB DELTA4 desaturase, MDES, membrane lipid desaturase, MLD, SPBC3B8.07c, sphingolipid DELTA4-desaturase

ECTree

     1 Oxidoreductases
         1.14 Acting on paired donors, with incorporation or reduction of molecular oxygen
             1.14.19 With oxidation of a pair of donors resulting in the reduction of O2 to two molecules of water
                1.14.19.17 sphingolipid 4-desaturase

Storage Stability

Storage Stability on EC 1.14.19.17 - sphingolipid 4-desaturase

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STORAGE STABILITY
ORGANISM
UNIPROT
LITERATURE
-4°C, phosphate buffer (100 mM NaH2PO4/Na2HPO4, pH 7.4), 7 days, approximately 50% of the activity is lost
-80°C, phosphate buffer (100 mM NaH2PO4/Na2HPO4, pH 7.4), 1 year, approximately 50% of the activity is lost
37°C, phosphate buffer (100 mM NaH2PO4/Na2HPO4, pH 7.4), 3 h, approximately 50% of the activity is lost