Any feedback?
Please rate this page
(all_enzymes.php)
(0/150)

BRENDA support

1.1.1.119: glucose 1-dehydrogenase (NADP+)

This is an abbreviated version!
For detailed information about glucose 1-dehydrogenase (NADP+), go to the full flat file.

Word Map on EC 1.1.1.119

Reaction

D-glucose
+
NADP+
=
D-glucono-1,5-lactone
+
NADPH
+
H+

Synonyms

beta-D-glucose: NAD(P) 1-oxidoreductase, dehydrogenase, glucose (nicotinamide adenine dinucleotide phosphate), GDH, GlcDH, GlcDH 2, glucose dehydrogenase, glucose-1-dehydrogenase, glucose-1-DH, halophilic glucose dehydrogenase, Hm GDH, NAD(P)+ glucose dehydrogenase, NAD(P)-dependent GDH, NADP-dependent glucose dehydrogenase, NADP-glucose-1-dehydrogenase, NADP-linked aldohexose dehydrogenase, nicotinamide adenine dinucleotide (phosphate)-dependent glucose-1-dehydrogenase, nicotinamide adenine dinucleotide phosphate-linked aldohexose dehydrogenase, STK_17040

ECTree

     1 Oxidoreductases
         1.1 Acting on the CH-OH group of donors
             1.1.1 With NAD+ or NADP+ as acceptor
                1.1.1.119 glucose 1-dehydrogenase (NADP+)

Substrates Products

Substrates Products on EC 1.1.1.119 - glucose 1-dehydrogenase (NADP+)

Please wait a moment until all data is loaded. This message will disappear when all data is loaded.
SUBSTRATE
PRODUCT                       
REACTION DIAGRAM
ORGANISM
UNIPROT
COMMENTARY
(Substrate) hide
LITERATURE
(Substrate)
COMMENTARY
(Product) hide
LITERATURE
(Product)
Reversibility
r=reversible
ir=irreversible
?=not specified
2-amino-2-deoxy-D-mannose + NADP+
2-amino-2-deoxy-D-mannono-1,5-lactone + NADPH
show the reaction diagram
-
-
-
-
?
2-deoxy-D-glucose + NADP+
2-deoxy-D-glucono-1,5-lactone + NADPH + H+
show the reaction diagram
-
-
-
-
?
beta-D-galactose + NADP+
D-galactono-1,5-lactone + NADPH
show the reaction diagram
-
-
-
?
beta-D-glucose + NAD+
?
show the reaction diagram
beta-D-glucose + NAD+
D-glucono-1,5-lactone + NADH + H+
show the reaction diagram
the enzyme has a strong preference for NADP+ over NAD+
-
-
?
beta-D-glucose + NADP+
?
show the reaction diagram
beta-D-glucose + NADP+
D-glucono-1,5-lactone + NADPH + H+
show the reaction diagram
D-glucose + 1,N6-ethanoadenine-NADP+
D-glucono-1,5-lactone + 1,N6-ethanoadenine-NADPH
show the reaction diagram
D-glucose + N1-(2-aminoethyl)-NADP+
D-glucono-1,5-lactone + N1-(2-aminoethyl)-NADPH
show the reaction diagram
D-glucose + N6-(2-aminoethyl)-NADP+
D-glucono-1,5-lactone + N6-(2-aminoethyl)-NADPH
show the reaction diagram
D-glucose + NAD(P)+
D-glucono-1,5-lactone + NAD(P)H + H+
show the reaction diagram
-
-
-
?
D-glucose + NAD+
D-glucono-1,5-lactone + NADH
show the reaction diagram
D-glucose + NAD+
D-glucono-1,5-lactone + NADH + H+
show the reaction diagram
-
-
-
?
D-glucose + NADP+
D-glucono-1,5-lactone + NADPH
show the reaction diagram
-
-
-
?
D-glucose + NADP+
D-glucono-1,5-lactone + NADPH + H+
show the reaction diagram
D-glucose + polyethylene glycol(MW 20000)-N6-(2-aminoethyl)-NADP+
D-glucono-1,5-lactone + polyethylene glycol(MW 20000)-N6-(2-aminoethyl)-NADPH + H+
show the reaction diagram
-
-
-
-
r
D-mannose + NADP+
D-mannono-1,5-lactone + NADPH
show the reaction diagram
additional information
?
-
-
reduction of C=N bonds with good levels of conversion (more than 50%) and excellent enantioselectivity (up to more than 99% enantiomeric excess) by glucose dehydrogenase represents a promiscuous catalytic activity of this enzyme
-
-
-