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EC Number
Substrates
Commentary Substrates
Organism
Products
Commentary (Products)
Reversibility
1.14.18.5
sphinganine + reduced acceptor + H+ + O2
-
Arabidopsis thaliana
phytosphinganine + acceptor + H2O
-
?
1.14.18.5
dihydroceramide + reduced acceptor + H+ + O2
-
Homo sapiens
phytoceramide + acceptor + H2O
-
?
1.14.18.5
N-octanoyl-D-erythro-dihydrosphingosine + reduced acceptor + H+ + O2
-
Homo sapiens
?
-
?
1.14.18.5
sphingosine + reduced acceptor + H+ + O2
-
Homo sapiens
phytosphingosine + acceptor + H2O
-
?
1.14.18.5
more
enzyme is a bifunctional sphingolipid DELTA4-desaturase/C4-hydroxylase, with the desaturase activity being one order of magnitude higher than the hydroxylase activity
Leishmania major
?
-
?
1.14.18.5
sphinganine ceramide + 2 ferrocytochrome b5 + O2 + 2 H+
-
Mus musculus
4-hydroxysphinganine ceramide + 2 ferricytochrome b5 + H2O
plus (E)-sphing-4-enine ceramide, the (E)-sphing-4-enine/4-hydroxysphinganine ratio is 2.5:1
?
1.14.18.5
dihydroceramide + reduced acceptor + H+ + O2
-
Saccharomyces cerevisiae
?
-
?
1.14.18.5
dihydrosphingosine + NADPH + H+ + O2
-
Saccharomyces cerevisiae
phytosphingosine + NADP+ + H2O
-
?
1.14.18.5
DL-erythro-dihydrosphingosine + reduced acceptor + H+ + O2
-
Saccharomyces cerevisiae
phytosphingosine + acceptor + H2O
-
?
1.14.18.5
dihydroceramide + reduced acceptor + H+ + O2
-
Saccharomyces cerevisiae W303C
?
-
?
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