EC Number   |
Substrates |
Organism |
Products |
Reversibility |
|---|
   1.14.18.5 | D-erythro-eicosasphinganine + NADH + H+ + O2 |
- |
Zea mays |
4-hydroxyeicosasphinganine + NAD+ + H2O |
- |
? |
| 1.14.18.5 | D-erythro-sphinganine + NADPH + H+ + O2 |
- |
Zea mays |
4-hydroxysphinganine + NADP+ + H2O |
- |
? |
| 1.14.18.5 | dihydroceramide + reduced acceptor + H+ + O2 |
- |
Saccharomyces cerevisiae |
? |
- |
? |
| 1.14.18.5 | dihydroceramide + reduced acceptor + H+ + O2 |
- |
Saccharomyces cerevisiae W303C |
? |
- |
? |
| 1.14.18.5 | dihydroceramide + reduced acceptor + H+ + O2 |
- |
Homo sapiens |
phytoceramide + acceptor + H2O |
- |
? |
| 1.14.18.5 | dihydrosphingosine + NADPH + H+ + O2 |
- |
Saccharomyces cerevisiae |
phytosphingosine + NADP+ + H2O |
- |
? |
| 1.14.18.5 | DL-erythro-dihydrosphingosine + reduced acceptor + H+ + O2 |
- |
Saccharomyces cerevisiae |
phytosphingosine + acceptor + H2O |
- |
? |
| 1.14.18.5 | DL-erythro-dihydrosphingosine + reduced acceptor + H+ + O2 |
- |
Saccharomyces cerevisiae W303C |
phytosphingosine + acceptor + H2O |
- |
? |
| 1.14.18.5 | more |
DL-threo-sphinganine is not an effective substrate. Individual ceramide species having 2-, 6-,8-, or 24-carbon fatty acyl chains amide-linked to sphinganine are hydroxylated with similar efficiency as free sphinganine |
Zea mays |
? |
- |
? |
| 1.14.18.5 | more |
enzyme is a bifunctional sphingolipid DELTA4-desaturase/C4-hydroxylase, with the desaturase activity being one order of magnitude higher than the hydroxylase activity |
Leishmania major |
? |
- |
? |
