EC Number |
Application |
Reference |
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1.3.1.24 | diagnostics |
antiapoptotic effect of the enzyme in cancers portens strategies for developing novel biomarkers and effective treatment ways for cancer patients |
763307 |
1.3.1.24 | diagnostics |
peripheral biomarker for the early diagnosis of Alzheimer's disease |
763055 |
1.3.1.24 | medicine |
biliverdin reductase B is a prostate cancer marker |
740909 |
1.3.1.24 | medicine |
BVR may represent a novel strategy for the treatment of multiple sclerosis and other oxidative stress-mediated diseases, treatment with BVR ameliorates both clinical and pathological signs of autoimmune encephalomyelitis more efficiently than treatments with traditional antioxidant enzymes |
673797 |
1.3.1.24 | medicine |
data gathered to date have identified the potential utility of hBVR in modulating cell signaling and the wide range of functions that are regulated by protein kinases that include growth, differentiation, gene transcription and metabolism, regulation of glucose uptake, induction of HO-1, and cytokine and Toll-like receptor signaling are potential target candidates for hBVR-based therapeutic strategies |
701357 |
1.3.1.24 | medicine |
finding that BVR and HO-2 levels, myocyte apoptosis, and contractile function of the heart can be modulated by small human BVR-based peptides offers a promising therapeutic approach for treatment of cardiac dysfunctions |
711965 |
1.3.1.24 | medicine |
hyperbiliverdinaemia, green jaundice, with green plasma and urine may be caused by a genetic defect in the BVR-A gene in conjunction with decompensated liver cirrosis |
699950 |
1.3.1.24 | medicine |
Tat-mediated transduction of biliverdin reductase A may provide a potential tool to ameliorate beta-cell deficit in pancreas with type 2 diabetes mellitus |
740267 |
1.3.1.24 | medicine |
therapeutic potential of human BVR and human HVR-based peptides by affecting the MAPK signaling pathways, overview |
711795 |
1.3.1.24 | more |
BVR regualtes cellular levels of biliverdin, a potent gene regulator and determinant factor for dorsal axis development in Xenopus larva |
676353 |