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Literature summary for 1.3.1.24 extracted from

  • Lee, S.J.; Kang, H.K.; Eum, W.S.; Park, J.; Choi, S.Y.; Kwon, H.Y.
    Tat-biliverdin reductase A protects INS-1 cells from human islet amyloid polypeptide-induced cytotoxicity by alleviating oxidative stress and ER stress (2017), Cell Biol. Int., 41, 514-524.
    View publication on PubMed

Application

Application Comment Organism
medicine Tat-mediated transduction of biliverdin reductase A may provide a potential tool to ameliorate beta-cell deficit in pancreas with type 2 diabetes mellitus Homo sapiens

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
biliverdin + NADH + H+ Homo sapiens
-
bilirubin + NAD+
-
r
biliverdin + NADPH + H+ Homo sapiens
-
bilirubin + NADP+
-
r

Organism

Organism UniProt Comment Textmining
Homo sapiens P53004
-
-

Source Tissue

Source Tissue Comment Organism Textmining
INS-1 cell
-
Homo sapiens
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
biliverdin + NADH + H+
-
Homo sapiens bilirubin + NAD+
-
r
biliverdin + NADPH + H+
-
Homo sapiens bilirubin + NADP+
-
r

Synonyms

Synonyms Comment Organism
biliverdin reductase A
-
Homo sapiens
BLVRA
-
Homo sapiens

Cofactor

Cofactor Comment Organism Structure
NADH
-
Homo sapiens
NADPH
-
Homo sapiens