EC Number   |
Inhibitors |
Structure |
|---|
   2.7.7.8 | dADP |
0.16 mM, more than 80% inhibition of ADP polymerization |
   |
| 2.7.7.8 | dADP |
competitive inhibition of de novo polymerization of ADP by primer-independent form I and primer-dependent form T |
|
| 2.7.7.8 | dATP |
5 mM, 28°C, presence of MgCl2, 39% residual activity |
|
| 2.7.7.8 | dGTP |
5 mM, 28°C, presence of MgCl2, 40% residual activity |
|
| 2.7.7.8 | GDP |
0.8 mM, more than 80% inhibition of ADP polymerization |
|
| 2.7.7.8 | GTP |
5 mM, 28°C, presence of MgCl2, 65% residual activity |
|
| 2.7.7.8 | heparin |
- |
|
| 2.7.7.8 | hydrogen peroxide |
upon exposure of human cells, the amount of enzyme protein decreases rapidly |
|
| 2.7.7.8 | menadione |
upon exposure of human cells, the amount of enzyme protein decreases rapidly |
|
| 2.7.7.8 | Mg2+ |
stimulates ADP polymerization maximally at 10 mM, GDP polymerization maximally at 5 mM, inhibition above |
|
