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Information on EC 6.2.1.13 - acetate-CoA ligase (ADP-forming)

for references in articles please use BRENDA:EC6.2.1.13

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IUBMB Comments

Also acts on propanoate and, very slowly, on butanoate.

The expected taxonomic range for this enzyme is: Bacteria, Archaea, Eukaryota
Reaction Schemes

Synonyms
acs iii, acetyl-coa synthetase (adp-forming), adp-acs, acetate:coa ligase [adp-forming], tk0944/tk0943 protein, more

REACTION
REACTION DIAGRAM
COMMENTARY hide
ORGANISM
UNIPROT
LITERATURE
ATP + acetate + CoA = ADP + phosphate + acetyl-CoA
show the reaction diagram
PATHWAY SOURCE
PATHWAYS
MetaCyc
acetate and ATP formation from acetyl-CoA II, methoxylated aromatic compound degradation II, pyruvate fermentation to acetate III
Highest Expressing Human Cell Lines
Cell Line Links Gene Links