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Literature summary for 6.2.1.13 extracted from

  • Reeves, R.E.; Warren, L.G.; Susskind, B.; Lo, H.S.
    An energy-conserving pyruvate-to-acetate pathway in Entamoeba histolytica. Pyruvate synthase and a new acetate thiokinase (1977), J. Biol. Chem., 252, 726-731.
    View publication on PubMed

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
ADP + phosphate + acetyl-CoA Entamoeba histolytica enzyme catalyzes acetate formation and ATP generation during fermentation of pyruvate to acetate ?
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?
ADP + phosphate + acetyl-CoA Entamoeba histolytica energy-conserving pyruvate-to-acetate pathway ?
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?

Organism

Organism UniProt Comment Textmining
Entamoeba histolytica
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-
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Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
ADP + phosphate + acetyl-CoA
-
Entamoeba histolytica ATP + acetate + CoA
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?
ADP + phosphate + acetyl-CoA enzyme catalyzes acetate formation and ATP generation during fermentation of pyruvate to acetate Entamoeba histolytica ?
-
?
ADP + phosphate + acetyl-CoA energy-conserving pyruvate-to-acetate pathway Entamoeba histolytica ?
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?
ATP + n-butyrate + CoA s.o. Entamoeba histolytica ADP + phosphate + n-butyryl-CoA
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?
ATP + n-butyrate + CoA 3% of the activity relative to acetate Entamoeba histolytica ADP + phosphate + n-butyryl-CoA
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?
ATP + propionate + CoA at 47% of the activity relative to acetate Entamoeba histolytica ADP + phosphate + propionyl-CoA
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?
GDP + phosphate + acetyl-CoA
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Entamoeba histolytica GTP + acetate + CoA
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?
IDP + phosphate + acetyl-CoA
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Entamoeba histolytica ITP + acetate + CoA
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?