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Results 1 - 8 of 8
EC Number General Information Commentary Reference
Show all pathways known for 6.2.1.13Display the word mapDisplay the reaction diagram Show all sequences 6.2.1.13evolution the enzyme is a member of the NDP-forming acyl-CoA synthetase enzyme superfamily 744911
Show all pathways known for 6.2.1.13Display the word mapDisplay the reaction diagram Show all sequences 6.2.1.13malfunction amoebae lacking enzyme activity are unable to reestablish the acetyl-CoA/CoA ratio after an oxidative stress challenge 744414
Show all pathways known for 6.2.1.13Display the word mapDisplay the reaction diagram Show all sequences 6.2.1.13malfunction gradual ACS gene silencing (49-93%) significantly decreases the acetate flux without affecting the levels of glycolytic metabolites and ATP in trophozoites. Amoebae lacking ACS activity are unable to reestablish the acetyl-CoA/CoA ratio after an oxidative stress challenge 744414
Show all pathways known for 6.2.1.13Display the word mapDisplay the reaction diagram Show all sequences 6.2.1.13metabolism the enzyme is related to the phosphate-dependent fermentative glycolysis in Entamoeba histolytica. The end-products of carbohydrate catabolism in the parasite are ethanol and acetate, produced by the bifunctional aldehyde-alcohol dehydrogenase (ADHE) and ACS, respectively, overview 744414
Show all pathways known for 6.2.1.13Display the word mapDisplay the reaction diagram Show all sequences 6.2.1.13metabolism the main role of the enzyme in the parasite energy metabolism is to recycle CoA for glycolysis to proceed under aerobic conditions 744414
Show all pathways known for 6.2.1.13Display the word mapDisplay the reaction diagram Show all sequences 6.2.1.13more residue His252 is essential for enzymatic activity, substrate binding structure and mechanism, overview 744911
Show all pathways known for 6.2.1.13Display the word mapDisplay the reaction diagram Show all sequences 6.2.1.13physiological function Archaeoglobus fulgidus strain 7324 converts starch to acetate via a modified Embden-Meyerhof pathway and acetyl-CoA synthetase (ADP-forming) -, 721449
Show all pathways known for 6.2.1.13Display the word mapDisplay the reaction diagram Show all sequences 6.2.1.13physiological function growth arrest is caused by elevated Acs, EC 6.2.1.1, activity, while overproduction of ADP-forming Ac-CoA synthesizing systems do not affect the growth behaviour of acetylation-deficient or acetylation-proficient strains 716267
Results 1 - 8 of 8