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Information on EC 3.5.4.25 - GTP cyclohydrolase II

for references in articles please use BRENDA:EC3.5.4.25
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IUBMB Comments
Two C-N bonds are hydrolysed, releasing formate, with simultaneous removal of the terminal diphosphate.
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Word Map
The expected taxonomic range for this enzyme is: Eukaryota, Bacteria
Synonyms
3,4-dihydroxy-2-butanone 4-phosphate synthase, GCH II, GCH II/III, GCH-II, GCHII, GTP cyclohydrolase II, GTP cyclohydrolase-II, GTP-8-formylhydrolase, GTPCH II, GTPCH-II, more
REACTION
REACTION DIAGRAM
COMMENTARY hide
ORGANISM
UNIPROT
LITERATURE
GTP + 3 H2O = formate + 2,5-diamino-6-hydroxy-4-(5-phospho-D-ribosylamino)pyrimidine + diphosphate
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