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Information on EC 3.4.22.56 - caspase-3
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EC Tree
3.4.22.56 caspase-3Specify your search results
Word Map
- 3.4.22.56
- bcl-2
- caspase-9
- necrosis
-
tunel
- parp
-
anti-apoptotic
-
neuroprotective
-
pro-apoptotic
- tnf
- endothelial
-
annexin
- leukemia
-
apoptosis-related
- mapks
- fas
- ischemia
- dismutase
-
deoxynucleotidyl
- erk
-
neurotoxicity
- artery
- cyclin
- cerebral
- dutp
- malondialdehyde
-
reperfusion
- infarct
- nick
- cardiac
- sirna
-
apoptosis-inducing
- myocardial
- gsh
- cardiomyocytes
-
sham
- c-jun
- cisplatin
- survivin
-
transferase-mediated
- iodide
- hippocampal
- adp-ribose
-
hoechst
-
antiproliferative
-
caspase-dependent
-
polyadp-ribose
- bid
-
ischemia-reperfusion
- propidium
-
ladder
- analysis
- drug development
- molecular biology
- medicine
- diagnostics
The enzyme appears in viruses and cellular organisms
Reaction Schemes
strict requirement for an Asp residue at positions P1 and P4. It has a preferred cleavage sequence of Asp-Xaa-Xaa-Asp-/- with a hydrophobic amino-acid residue at P2 and a hydrophilic amino-acid residue at P3, although Val or Ala are also accepted at this position
Synonyms
caspase-3, caspase 3, casp3, sca-1, cpp32, casp-3, cas-3, cpp-32, apopain, cgcaspase-3, 
more
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SYNONYM 
ORGANISM
UNIPROT
COMMENTARY 
LITERATURE
apopain
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-
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C14.003
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CASP-3
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-
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caspase 3
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-
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CPP-32
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-
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CPP32
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-
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CPP32/apopain
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cysteine protease CPP32
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-
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IRP
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-
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SCA-1
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-
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SREBP cleavage activity 1
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Yama protein
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-
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Yama/CPP32
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-
additional information
caspase-3 belongs to the group of executioner caspases of the family of cysteine aspartyl proteases
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REACTION
REACTION DIAGRAM
COMMENTARY
ORGANISM
UNIPROT
LITERATURE
strict requirement for an Asp residue at positions P1 and P4. It has a preferred cleavage sequence of Asp-Xaa-Xaa-Asp-/- with a hydrophobic amino-acid residue at P2 and a hydrophilic amino-acid residue at P3, although Val or Ala are also accepted at this position
hydrophobic S5 site, where the side-chains of F250 and F252 interact with substrate. Kinetic importance of P5 site
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REACTION TYPE
ORGANISM
UNIPROT
COMMENTARY
LITERATURE
hydrolysis of peptide bond
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-
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-
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CAS REGISTRY NUMBER
COMMENTARY
169592-56-7
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SUBSTRATE
PRODUCT
REACTION DIAGRAM
ORGANISM
UNIPROT
COMMENTARY
(Substrate)
(Substrate)
LITERATURE
(Substrate)
(Substrate)
COMMENTARY
(Product)
(Product)
LITERATURE
(Product)
(Product)
Reversibility
r=reversible
ir=irreversible
?=not specified
r=reversible
ir=irreversible
?=not specified
acetyl-DEVD-7-amido-4-methylcoumarin + H2O
acetyl-DEVD + 7-amino-4-methylcoumarin
-
-
-
?
acetyl-L-Asp-L-Glu-L-Val-L-Asp-4-nitroanilide + H2O
acetyl-L-Asp-L-Glu-L-Val-L-Asp + 4-nitroaniline
-
-
-
?
acetyl-L-Asp-L-Glu-L-Val-L-Asp-7-amido-4-methylcoumarin + H2O
acetyl-L-Asp-L-Glu-L-Val-L-Asp + 7-amino-4-methylcoumarin
-
-
-
?
acetyl-L-Asp-L-Met-L-Gln-L-Asp-4-nitroanilide + H2O
acetyl-L-Asp-L-Met-L-Gln-L-Asp + 4-nitroaniline
-
-
-
?
acetyl-L-Asp-L-Val-L-Ala-L-Asp-4-nitroanilide + H2O
acetyl-L-Asp-L-Val-L-Ala-L-Asp + 4-nitroaniline
-
-
-
?
acetyl-L-Leu-L-Asp-L-Val-L-Ala-L-Asp-4-nitroanilide + H2O
acetyl-L-Leu-L-Asp-L-Val-L-Ala-L-Asp + 4-nitroaniline
-
-
-
?
acetyl-L-Val-L-Asp-L-Val-L-Ala-L-Asp-4-nitroanilide + H2O
acetyl-L-Val-L-Asp-L-Val-L-Ala-L-Asp + 4-nitroaniline
-
-
-
?
benzoyl-L-Asp-L-Glu-L-Val-L-Asp-7-amido-4-methylcoumarin + H2O
benzoyl-L-Asp-L-Glu-L-Val-L-Asp + 7-amino-4-methylcoumarin
-
-
-
?
DEVD-amido-4-trifluoromethylcoumarin + H2O
DEVD + amino-4-trifluoromethylcoumarin
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-
-
?
N-(5(6)-carboxyfluoresceinyl)-6-aminohexanoyl-Asp-Ala-Pro-Asp-6-aminohexanoyl-N6-[methyl red]-Lys-[N-(6-aminohexyl)-Gly]8-N2-(6-aminohexyl)-Gly-NH2 + H2O
?
-
-
-
?
N-(5(6)-carboxyfluoresceinyl)-6-aminohexanoyl-Asp-Ala-Val-Asp-6-aminohexanoyl-N6-[methyl red]-Lys-[N-(6-aminohexyl)-Gly]8-N2-(6-aminohexyl)-Gly-NH2 + H2O
?
-
-
-
?
N-(5(6)-carboxyfluoresceinyl)-6-aminohexanoyl-Asp-Asn-Pro-Asp-6-aminohexanoyl-N6-[methyl red]-Lys-[N-(6-aminohexyl)-Gly]8-N2-(6-aminohexyl)-Gly-NH2 + H2O
?
-
-
-
?
N-(5(6)-carboxyfluoresceinyl)-6-aminohexanoyl-Asp-Asn-Val-Asp-6-aminohexanoyl-N6-[methyl red]-Lys-[N-(6-aminohexyl)-Gly]8-N2-(6-aminohexyl)-Gly-NH2 + H2O
?
-
-
-
?
N-(5(6)-carboxyfluoresceinyl)-6-aminohexanoyl-Asp-Glu-Val-Asp-6-aminohexanoyl-N6-[methyl red]-Lys-[N-(6-aminohexyl)-Gly]8-N2-(6-aminohexyl)-Gly-NH2 + H2O
?
-
-
-
?
N-(5(6)-carboxyfluoresceinyl)-6-aminohexanoyl-Asp-Gly-Pro-Asp-6-aminohexanoyl-N6-[methyl red]-Lys-[N-(6-aminohexyl)-Gly]8-N2-(6-aminohexyl)-Gly-NH2 + H2O
?
-
-
-
?
N-(5(6)-carboxyfluoresceinyl)-6-aminohexanoyl-Asp-Gly-Val-Asp-6-aminohexanoyl-N6-[methyl red]-Lys-[N-(6-aminohexyl)-Gly]8-N2-(6-aminohexyl)-Gly-NH2 + H2O
?
-
-
-
?
N-(5(6)-carboxyfluoresceinyl)-6-aminohexanoyl-Asp-Leu-Pro-Asp-6-aminohexanoyl-N6-[methyl red]-Lys-[N-(6-aminohexyl)-Gly]8-N2-(6-aminohexyl)-Gly-NH2 + H2O
?
-
-
-
?
N-(5(6)-carboxyfluoresceinyl)-6-aminohexanoyl-Asp-Leu-Pro-Asp-N6-[methyl red]-Lys-6-aminohexanoyl-[N-(6-aminohexyl)-Gly]8-N2-(6-aminohexyl)-Gly-NH2 + H2O
?
the substrate is able to detect and quantify caspase-3 activity in apoptotic cells without cross-reactivity by caspase-7
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-
?
N-(5(6)-carboxyfluoresceinyl)-6-aminohexanoyl-Asp-Leu-Val-Asp-6-aminohexanoyl-N6-[methyl red]-Lys-[N-(6-aminohexyl)-Gly]8-N2-(6-aminohexyl)-Gly-NH2 + H2O
?
-
-
-
?
N-(5(6)-carboxyfluoresceinyl)-6-aminohexanoyl-Asp-Val-Pro-Asp-6-aminohexanoyl-N6-[methyl red]-Lys-[N-(6-aminohexyl)-Gly]8-N2-(6-aminohexyl)-Gly-NH2 + H2O
?
-
-
-
?
N-(5(6)-carboxyfluoresceinyl)-6-aminohexanoyl-Asp-Val-Val-Asp-6-aminohexanoyl-N6-[methyl red]-Lys-[N-(6-aminohexyl)-Gly]8-N2-(6-aminohexyl)-Gly-NH2 + H2O
?
-
-
-
?
tau protein + H2O
?
cleavage by caspase-3 is a crucial upstream event associated with Tau self-assembly leading to Alzheimer's Disease pathogenesis
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-
?
tau protein + H2O
?
peptides are designed from 441-mer major human Tau protein sequence that encompasses the proposed caspase-3 cleavage site (Asp421-/-Ser422). While the control peptide is efficiently cleaved by caspase-3 at Asp421-/-Ser422 site producing the expected N- and C-terminal fragment peptides, the corresponding phospho-Ser422 peptide remains completely resistant to the cleavage. Substitution of Asp421 by its dextro isoform also blocks peptide cleavage by caspase-3. However substitution of Ser422 by its dextro isoform in the peptide does not affect the cleavage significantly
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-
?
additional information
?
-
caspases are key effectors in the processes of apoptosis and inflammation, executioner caspases selectively hydrolyze cellular proteins in the pathways leading to cell death
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?
additional information
?
-
caspase-3 recognizes various P4 residues in its numerous protein substrates, Asp is the most frequent P4 residue in peptide substrates. Although a wide variety of P4 residues in the cellular proteins are cleaved by caspase-3. Hydrophobic residues appear in the relative frequency of Val-Ala-Leu-Met-Phe-Ile/Cys in descending order. The P4 residues forms favorable hydrophobic interactions in two separate hydrophobic regions of the binding site. The side chains of P4 Ile and Tyr form hydrophobic interactions with caspase-3 residues Trp206 and Trp214 within a non-polar pocket of the S4 subsite, while P4 Trp interacts with Phe250 and Phe252 that can also form the S5 subsite, adaptability of caspase-3 for binding diverse P4 residues, substrate specificity, overview
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-
?
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NATURAL SUBSTRATE
NATURAL PRODUCT
REACTION DIAGRAM
ORGANISM
UNIPROT
COMMENTARY
(Substrate)
(Substrate)
LITERATURE
(Substrate)
(Substrate)
COMMENTARY
(Product)
(Product)
LITERATURE
(Product)
(Product)
REVERSIBILITY
r=reversible
ir=irreversible
?=not specified
r=reversible
ir=irreversible
?=not specified
tau protein + H2O
?
cleavage by caspase-3 is a crucial upstream event associated with Tau self-assembly leading to Alzheimer's Disease pathogenesis
-
-
?
additional information
?
-
caspases are key effectors in the processes of apoptosis and inflammation, executioner caspases selectively hydrolyze cellular proteins in the pathways leading to cell death
-
-
?
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INHIBITOR
ORGANISM
UNIPROT
COMMENTARY
LITERATURE
IMAGE
(S)-(+)-5-[1-[2-(thiophenoxymethyl)pyrrolidinyl]sulfonyl]isatin
IC50: 44 nM
(S)-1-(4-pyridinylmethyl)-5-[1-[2-(phenoxymethyl)pyrrolidinyl]sulfonal]isatin
IC50: 4.2 nM
(S)-1-(carboxymethyl)-5-[1-[2-(phenoxymethyl)pyrrolidinyl]sulfonyl]isatin
IC50: 170 nM
(S)-1-(cyclohexylmethyl)-5-[1-[2-(phenoxymethyl)pyrrolidinyl]sulfonal]isatin
IC50: 5.2 nM
(S)-1-allyl-5-[1-[2-(phenoxymethyl)pyrrolidinyl]sulfonyl]isatin
IC50: 4.6 nM
(S)-1-benzyl-5-[1-[2-(phenoxymethyl)pyrrolidinyl]sulfonyl]isatin
IC50: 2.5 nM
(S)-1-methyl-5-[1-[2-(phenoxymethyl)pyrrolidinyl]sulfonyl]isatin
IC50: 30 nM
(S)-1-[(tert-butyloxycarbonyl)methyl]-5-[1-[2-(phenoxymethyl)pyrrolidinyl]sulfonyl]isatin
IC50: 3.1 nM
(S)-5-[1-[(2-tert-butoxycarbonyl)pyrrolidinyl]sulfonyl]isatin
IC50: 70 nM
(S)-5-[1-[2-(phenylaminocarbonyl)pyrrolidinyl]sulfonyl]isatin
IC50: 140 nM
(S)-5-[1-[[2-(dimethylamino)carbonyl]pyrrolidinyl]sulfonyl]isatin
IC50: 410 nM
Ac-IEPD-CHO
a reversible aldehyde caspase-3 inhibitor, bound in extended conformation in the S1-S4 substrate binding sites of caspase-3, binding structure with hydrogen bond and ionic interactions, overview
Ac-WEHD-CHO
a reversible aldehyde caspase-3 inhibitor, bound in extended conformation in the S1-S4 substrate binding sites of caspase-3, binding structure with hydrogen bond and ionic interactions, overview
Ac-YVAD-CHO
a reversible aldehyde caspase-3 inhibitor, bound in extended conformation in the S1-S4 substrate binding sites of caspase-3, binding structure with hydrogen bond and ionic interactions, overview
alpha-fetoprotein
interacts with caspase-3 through precise amino acids, namely loop-4 residues Glu-248, Asp-253 and His-257. alpha-Fetoprotein plays a critical role in the inhibition of the apoptotic signal transduction that mediated by caspase-3
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N-[(2-fluorophenyl)methyl]-N-methyl-2,3-dioxo-1-(prop-2-yn-1-yl)-2,3-dihydro-1H-indole-5-sulfonamide
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N-[(2-fluorophenyl)methyl]-N-methyl-2,3-dioxo-2,3-dihydro-1H-indole-5-sulfonamide
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N-[(3-fluorophenyl)methyl]-N-methyl-2,3-dioxo-1-(prop-2-yn-1-yl)-2,3-dihydro-1H-indole-5-sulfonamide
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N-[(3-fluorophenyl)methyl]-N-methyl-2,3-dioxo-2,3-dihydro-1H-indole-5-sulfonamide
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N-[(4-fluorophenyl)methyl]-N-methyl-2,3-dioxo-2,3-dihydro-1H-indole-5-sulfonamide
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ZINC13341044
screening of caspase-3 inhibitors from natural molecule database using e-pharmacophore and docking studies
ZINC13507846
screening of caspase-3 inhibitors from natural molecule database using e-pharmacophore and docking studies
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ACTIVATING COMPOUND
ORGANISM
UNIPROT
COMMENTARY
LITERATURE
IMAGE
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DISEASE
TITLE OF PUBLICATION
LINK TO PUBMED
1-acylglycerol-3-phosphate o-acyltransferase deficiency
ABHD5 interacts with BECN1 to regulate autophagy and tumorigenesis of colon cancer independent of PNPLA2.
Aberrant Crypt Foci
Activation of AMPK by chitosan oligosaccharide in intestinal epithelial cells: Mechanism of action and potential applications in intestinal disorders.
Aberrant Crypt Foci
Chemopreventive effect of the non-psychotropic phytocannabinoid cannabidiol on experimental colon cancer.
Aberrant Crypt Foci
Composition and chemopreventive effect of polysaccharides from common beans (Phaseolus vulgaris L.) on azoxymethane-induced colon cancer.
Aberrant Crypt Foci
Deciphering the molecular mechanism and apoptosis underlying the in-vitro and in-vivo chemotherapeutic efficacy of vanadium luteolin complex in colon cancer.
Aberrant Crypt Foci
Germinated brown rice combined with Lactobacillus acidophilus and Bifidobacterium animalis subsp. lactis inhibits colorectal carcinogenesis in rats.
Aberrant Crypt Foci
Role of anthocyanin-enriched purple-fleshed sweet potato p40 in colorectal cancer prevention.
Abortion, Habitual
Apoptosis is increased and cell proliferation is decreased in out-of-phase endometria from infertile and recurrent abortion patients.
Abortion, Spontaneous
Down-regulation of miR-378a-3p induces decidual cell apoptosis: a possible mechanism for early pregnancy loss.
Abortion, Spontaneous
Potential role of decidual apoptosis in the pathogenesis of miscarriages.
Abscess
Staphylococcus aureus Exploits the Host Apoptotic Pathway To Persist during Infection.
Acantholysis
Biphasic activation of p38MAPK suggests that apoptosis is a downstream event in pemphigus acantholysis.
Acantholysis
Novel mechanisms of target cell death and survival and of therapeutic action of IVIg in Pemphigus.
Acantholysis
Preclinical studies identify non-apoptotic low-level caspase-3 as therapeutic target in pemphigus vulgaris.
Acantholysis
The interaction of pemphigus autoimmunoglobulins with epidermal cells: activation of the fas apoptotic pathway and the use of caspase activity for pathogenicity tests of pemphigus patients.
Acanthoma
Apoptosis and anti-apoptotic heat shock proteins in canine cutaneous infundibular keratinizing acanthomas and squamous cell carcinomas.
Acidosis
A novel neuroprotective strategy for ischemic stroke: transient mild acidosis treatment by CO2 inhalation at reperfusion.
Acidosis
Acidosis causes endoplasmic reticulum stress and caspase-12-mediated astrocyte death.
Acidosis
Acidosis promotes cell apoptosis through the G protein-coupled receptor 4/CCAAT/enhancer-binding protein homologous protein pathway.
Acidosis
Influence of glutamine infusion on ubiquitin, caspase-3, cathepsins L and B, and m-calpain expression in sheep with nutritionally induced metabolic acidosis.
Acidosis
Mechanisms stimulating muscle wasting in chronic kidney disease: the roles of the ubiquitin-proteasome system and myostatin.
Acidosis
Melatonin regulates tumor aggressiveness under acidosis condition in breast cancer cell lines.
Acidosis
Mild acidosis delays neutrophil apoptosis via multiple signaling pathways and acts in concert with inflammatory mediators.
Acidosis
Muscle wasting in hemodialysis patients: new therapeutic strategies for resolving an old problem.
Acidosis
Plasma amino acid concentrations and mRNA expression of components related to protein degradation in lambs with nutritionally induced metabolic acidosis.
Acidosis
Platelet-activating factor-induced chloride channel activation is associated with intracellular acidosis and apoptosis of intestinal epithelial cells.
Acidosis
[Expressions of PDCD5 and other apoptosis-related proteins in muscle of patients with mitochondrial cytopathy]
Acquired Immunodeficiency Syndrome
Increased sensitivity of T lymphocytes to tumor necrosis factor receptor 1 (TNFR1)- and TNFR2-mediated apoptosis in HIV infection: relation to expression of Bcl-2 and active caspase-8 and caspase-3.
Acquired Immunodeficiency Syndrome
Involvement of caspase-3 pathway in anti-apoptotic action of methionine enkephalin on CEMx174 cells in prolonged infection with simian immunodeficiency virus in vitro.
Acute Kidney Injury
A Retrospective Cohort Analysis Shows that Coadministration of Minocycline with Colistin in Critically Ill Patients Is Associated with Reduced Frequency of Acute Renal Failure.
Acute Kidney Injury
Caspase-3-dependent peritubular capillary dysfunction is pivotal for the transition from acute to chronic kidney disease after acute ischemia-reperfusion injury.
Acute Kidney Injury
Ligustrazine suppresses renal NMDAR1 and caspase-3 expressions in a mouse model of sepsis-associated acute kidney injury.
Acute Kidney Injury
Negative Regulation of TGF? Signaling by Stem Cell Antigen-1 Protects against Ischemic Acute Kidney Injury.
Acute Kidney Injury
Pravastatin Attenuates Carboplatin-Induced Nephrotoxicity in Rodents via Peroxisome Proliferator-Activated Receptor Alpha Regulated Heme Oxygenase-1.
Acute Kidney Injury
Protective effect and mechanism of IL-10 on renal ischemia-reperfusion injury.
Acute Kidney Injury
Pyruvate dehydrogenase kinase 4 deficiency attenuates cisplatin-induced acute kidney injury.
Acute Kidney Injury
[The effect of caspase-3 inhibitor on the concentrations of serum inflammatory cytokines in sepsis related acute kidney injury induced by peritoneal cavity infection in mice.]
Acute Lung Injury
Photobiomodulation prevents DNA fragmentation of alveolar epithelial cells and alters the mRNA levels of caspase 3 and Bcl-2 genes in acute lung injury.
Acute Lung Injury
Recombinant human milk fat globule-EGF factor VIII (rhMFG-E8) as a therapy for sepsis after acute exposure to alcohol.
Acute Lung Injury
Silencing of fas, fas-associated via death domain, or caspase 3 differentially affects lung inflammation, apoptosis, and development of trauma-induced septic acute lung injury.
Acute Lung Injury
The protective effect of ethyl pyruvate on lung injury after burn in rats.
Acute Lung Injury
Therapeutic accessibility of caspase-mediated cell death as a key pathomechanism in indirect acute lung injury.
Acute Lung Injury
[The effect of paraquat on voltage-dependent anion channel and caspase-3, 8, 9 in the mitochondria of rat lung].
Acute-On-Chronic Liver Failure
Characterization of pro-apoptotic effect of liver failure plasma on primary human hepatocytes and its modulation by molecular adsorbent recirculation system therapy.
Addison Disease
Impaired caspase-3 expression by peripheral T cells in chronic autoimmune thyroiditis and in autoimmune polyendocrine syndrome-2.
Adenocarcinoma
A practical method to determine the amount of tissue to analyze using laser scanning cytometry.
Adenocarcinoma
Activation of caspase-3 in gastric adenocarcinoma AGS cells by Xylopia aethiopica (Dunal) A. Rich. fruit and characterization of its phenolic fingerprint by HPLC-DAD-ESI(Ion Trap)-MSn and UPLC-ESI-QTOF-MS2.
Adenocarcinoma
Alteration of fecal microbiota by fucoxanthin results in prevention of colorectal cancer in AOM/DSS-treated mice.
Adenocarcinoma
Annonaceous acetogenin mimic AA005 induces cancer cell death via apoptosis inducing factor through a caspase-3-independent mechanism.
Adenocarcinoma
Antiproliferative Activity of Cissus quadrangularis L. Extract against Human Cervical Cancer Cells: In Vitro and In Silico Analysis.
Adenocarcinoma
Antiproliferative and Proapoptotic Activities of Marine Sponge Hyrtios erectus Extract on Breast Carcinoma Cell Line (MCF-7).
Adenocarcinoma
Apoptosis associated with esophageal adenocarcinoma: influence of photodynamic therapy.
Adenocarcinoma
Apoptosis in different gastric lesions and gastric cancer: relationship with Helicobacter pylori, overexpression of p53 and aneuploidy.
Adenocarcinoma
Apoptosis of colorectal adenocarcinoma induced by 5-FU and/or IFN-gamma through caspase 3 and caspase 8.
Adenocarcinoma
Apoptotic Effect of Homobrassinin and Thiazino[6,5-b]indol is Associated with Downregulation of Heat Shock Proteins in Human Ovarian Adenocarcinoma Cells.
Adenocarcinoma
Argpyrimidine-modified Heat shock protein 27 in human non-small cell lung cancer: a possible mechanism for evasion of apoptosis.
Adenocarcinoma
Biobanking of Fresh-Frozen Human Adenocarcinomatous and Normal Colon Tissues: Which Parameters Influence RNA Quality?
Adenocarcinoma
Chicken Skin Mucosa Surrounding Adult Colorectal Adenomas is a Risk Factor for Carcinogenesis.
Adenocarcinoma
Cytoplasmic and nuclear maspin expression in lung carcinomas: an immunohistochemical study using tissue microarrays.
Adenocarcinoma
Diabodies targeting epithelial membrane protein 2 reduce tumorigenicity of human endometrial cancer cell lines.
Adenocarcinoma
Downregulation of phosphoglycerate dehydrogenase inhibits proliferation and enhances cisplatin sensitivity in cervical adenocarcinoma cells by regulating Bcl-2 and caspase-3.
Adenocarcinoma
Ellagic acid, a component of pomegranate fruit juice, suppresses androgen-dependent prostate carcinogenesis via induction of apoptosis.
Adenocarcinoma
Endothelial cell apoptosis in the context of quantification of angiogenesis in solid human adenocarcinomas: a novel double immunolabelling technique to identify endothelial cell apoptosis.
Adenocarcinoma
Exploring new applications of tulip tree (Liriodendron tulipifera L.): leaf essential oil as apoptotic agent for human glioblastoma.
Adenocarcinoma
Expression of cysteine protease protein 32 in prostatic adenocarcinoma correlates with tumor grade.
Adenocarcinoma
Expression of multiple apoptosis-regulatory genes in human breast cancer cell lines and primary tumors.
Adenocarcinoma
Expression of the bile acid receptor FXR in Barrett's esophagus and enhancement of apoptosis by guggulsterone in vitro.
Adenocarcinoma
Expression Profiling of Proliferation and Apoptotic Markers along the Adenoma-Carcinoma Sequence in Familial Adenomatous Polyposis Patients.
Adenocarcinoma
Features of the Copy Number Variation of Certain Genes in Tumor Cells in Patients with Serous Ovarian Adenocarcinoma.
Adenocarcinoma
Genistein sensitizes TRAIL-resistant human gastric adenocarcinoma AGS cells through activation of caspase-3.
Adenocarcinoma
Helicobacter pylori-induced changes in the gastric mucosa are associated with mitogen-activated protein kinase (MAPK) activation.
Adenocarcinoma
Identification of novel predictive markers for the prognosis of pancreatic ductal adenocarcinoma.
Adenocarcinoma
Induction of apoptosis by piperine in human cervical adenocarcinoma via ROS mediated mitochondrial pathway and caspase-3 activation.
Adenocarcinoma
Inhibitory Effect of Artesunate on Growth and Apoptosis of Gastric Cancer Cells.
Adenocarcinoma
Intensity of apoptosis as related to the expression of metallothionein (MT), caspase-3 (cas-3) and Ki-67 antigen and the survival time of patients with primary colorectal adenocarcinomas.
Adenocarcinoma
Iron oxide nanoparticles inhibit tumour growth by inducing pro-inflammatory macrophage polarization in tumour tissues.
Adenocarcinoma
Loss of caspase-1 and caspase-3 protein expression in human prostate cancer.
Adenocarcinoma
Melatonin inhibits cell growth and migration, but promotes apoptosis in gastric cancer cell line, SGC7901.
Adenocarcinoma
Metformin and epothilone A treatment up regulate pro-apoptotic PARP-1, Casp-3 and H2AX genes and decrease of AKT kinase level to control cell death of human hepatocellular carcinoma and ovary adenocarcinoma cells.
Adenocarcinoma
Nanomotor-Enabled pH-Responsive Intracellular Delivery of Caspase-3: Toward Rapid Cell Apoptosis.
Adenocarcinoma
NO-releasing aspirin exerts stronger growth inhibitory effect on Barrett's adenocarcinoma cells than traditional aspirin.
Adenocarcinoma
Oligonucleosomal DNA fragmentation in MCF-7 cells undergoing palmitate-induced apoptosis.
Adenocarcinoma
Pro-apoptotic effect of rice bran inositol hexaphosphate (IP6) on HT-29 colorectal cancer cells.
Adenocarcinoma
Proteolysis of the mismatch repair protein MLH1 by caspase-3 promotes DNA damage-induced apoptosis.
Adenocarcinoma
Rapid Induction of Lung Adenocarcinoma by Fibroblast Growth Factor 9 Signaling through FGF Receptor 3.
Adenocarcinoma
Reduced expression of caspase-8 and cleaved caspase-3 in pancreatic ductal adenocarcinoma cells.
Adenocarcinoma
Sanguinarine sensitizes human gastric adenocarcinoma AGS cells to TRAIL-mediated apoptosis via down-regulation of AKT and activation of caspase-3.
Adenocarcinoma
Secondary metabolic profiles and anticancer actions from fruit extracts of immature pomegranates.
Adenocarcinoma
Short hairpin RNA targeting c-FLIP sensitizes human cervical adenocarcinoma Hela cells to chemotherapy and radiotherapy.
Adenocarcinoma
Study of the Effects of 50Hz Homogeneous Magnetic Field on Expression of Bax, Bcl-2 and Caspase-3 of SNU Cells In Vitro.
Adenocarcinoma
Synergistic antitumor activity of pro-apoptotic agent PAC-1 with cisplatinum by the activation of CASP3 in pulmonary adenocarcinoma cell line H1299.
Adenocarcinoma
Targeting AKT with the proapoptotic peptide, TAT-CTMP: A novel strategy for the treatment of human pancreatic adenocarcinoma.
Adenocarcinoma
TPEN exerts antitumor efficacy in murine mammary adenocarcinoma through an H2O2 signaling mechanism dependent on caspase-3.
Adenocarcinoma
Tumor cell death induced by the inhibition of mitochondrial electron transport: The effect of 3-hydroxybakuchiol.
Adenocarcinoma
Tumor necrosis factor-related apoptosis inducing ligand (TRAIL)-induced apoptosis is dependent on activation of cysteine and serine proteases.
Adenocarcinoma
WITHDRAWN: Expression analysis of Sca-1 and its significance in lung cancers.
Adenocarcinoma
[Expression of livin in lung cancer tissue and its relationship with the expression of caspase-3.]
Adenocarcinoma
[Impact of preoperative drug therapy on the expression of apoptosis markers in colorectal liver metastases].
Adenocarcinoma of Lung
Antitumor activity of paclitaxel is significantly enhanced by a novel proapoptotic agent in non-small cell lung cancer.
Adenocarcinoma of Lung
Bufalin Induces Reactive Oxygen Species Dependent Bax Translocation and Apoptosis in ASTC-a-1 Cells.
Adenocarcinoma of Lung
Ceramide accumulation precedes caspase-3 activation during apoptosis of A549 human lung adenocarcinoma cells.
Adenocarcinoma of Lung
Ceramide induces apoptosis in human lung adenocarcinoma A549 cells through mitogen-activated protein kinases.
Adenocarcinoma of Lung
Curcumin reverses cis-platin resistance and promotes human lung adenocarcinoma A549/DDP cell apoptosis through HIF-1? and caspase-3 mechanisms.
Adenocarcinoma of Lung
FLIM and emission spectral analysis of caspase-3 activation inside single living cell during anticancer drug-induced cell death.
Adenocarcinoma of Lung
Ground-glass opacity-featured lung adenocarcinoma has no response to chemotherapy.
Adenocarcinoma of Lung
Increased Inhibition Effect of Antrodin C from the Stout Camphor Medicinal Mushroom, Taiwanofungus camphoratus (Agaricomycetes), on A549 through Crosstalk between Apoptosis and Autophagy.
Adenocarcinoma of Lung
Inhibition of proliferation and induction of apoptosis by trimethoxyl stilbene (TMS) in a lung cancer cell line.
Adenocarcinoma of Lung
Lung Adenocarcinoma Mouse Models Based on Orthotopic Transplantation of Syngeneic Tumor-Initiating Cells Expressing EpCAM, SCA-1, and Ly6d.
Adenocarcinoma of Lung
Methyl jasmonate induces apoptosis through induction of Bax/Bcl-XS and activation of caspase-3 via ROS production in A549 cells.
Adenocarcinoma of Lung
New 1,2,4-triazole-Chalcone hybrids induce Caspase-3 dependent apoptosis in A549 human lung adenocarcinoma cells.
Adenocarcinoma of Lung
Novel approaches to cancer therapy with ibuprofen-loaded Eudragit® RS 100 and/or octadecylamine-modified PLGA nanoparticles by assessment of their effects on apoptosis.
Adenocarcinoma of Lung
Olean-28,13b-olide 2 plays a role in cisplatin-mediated apoptosis and reverses cisplatin resistance in human lung cancer through multiple signaling pathways.
Adenocarcinoma of Lung
Oncogenic miR-137 contributes to cisplatin resistance via repressing CASP3 in lung adenocarcinoma.
Adenocarcinoma of Lung
Phosphoinositide specific phospholipase C?1 inhibition-driven autophagy caused cell death in human lung adenocarcinoma A549 cells in vivo and in vitro.
Adenocarcinoma of Lung
Prognostic significance of micropapillary pattern in lung adenocarcinoma and expression of apoptosis-related markers: caspase-3, bcl-2, and p53.
Adenocarcinoma of Lung
Role of insulin-like growth factor binding protein 2 in lung adenocarcinoma: IGF-independent antiapoptotic effect via caspase-3.
Adenocarcinoma of Lung
Role of leucine-rich pentatricopeptide repeat motif-containing protein (LRPPRC) for anti-apoptosis and tumourigenesis in cancers.
Adenocarcinoma of Lung
Spatio-temporal dynamic analysis of bid activation and apoptosis induced by alkaline condition in human lung adenocarcinoma cell.
Adenocarcinoma of Lung
Stable silencing of ROR1 regulates cell cycle, apoptosis, and autophagy in a lung adenocarcinoma cell line.
Adenocarcinoma of Lung
Sulforaphane sensitizes tumor necrosis factor-related apoptosis-inducing ligand-mediated apoptosis through downregulation of ERK and Akt in lung adenocarcinoma A549 cells.
Adenocarcinoma of Lung
The JNK inhibitor SP600125 enhances dihydroartemisinin-induced apoptosis by accelerating Bax translocation into mitochondria in human lung adenocarcinoma cells.
Adenocarcinoma of Lung
The study of effect and mechanism of 630-nm laser on human lung adenocarcinoma cell xenograft model in nude mice mediated by hematoporphyrin derivatives.
Adenocarcinoma of Lung
Therapeutic effect of Resveratrol in the treatment of osteoarthritis via the MALAT1/miR-9/NF-?B signaling pathway.
Adenocarcinoma of Lung
Ulinastatin protects against lipopolysaccharide-induced cardiac microvascular endothelial cell dysfunction via downregulation of lncRNA MALAT1 and EZH2 in sepsis.
Adenocarcinoma of Lung
[Construction of reversed caspase-3 and it's effect on apoptosis induction in human lung adenocarcinoma cell line A549]
Adenocarcinoma of Lung
[Effect of quercetin on the expression and growth of caspase-3 in lung adenocarcinoma cancer cell line A549.]
Adenocarcinoma of Lung
[Expression of livin in lung cancer tissue and its relationship with the expression of caspase-3.]
Adenocarcinoma of Lung
[Fluorescence emission analysis of caspase-3 activation induced by Xiao-Ai-Ping (XAP) inside living human lung adenocarcinoma cells]
Adenocarcinoma of Lung
[Promotive effect and its molecular mechanism of KLF5 on gemcitabine-induced apoptosis in human lung adenocarcinoma cell line H441].
Adenoma
A significant imbalance in mitosis versus apoptosis accelerates the growth rate of sessile serrated adenoma/polyps.
Adenoma
Chicken Skin Mucosa Surrounding Adult Colorectal Adenomas is a Risk Factor for Carcinogenesis.
Adenoma
Differential in vivo mechanism of chemoprevention of tumor formation in azoxymethane/dextran sodium sulfate mice by PEITC and DBM.
Adenoma
Expression of the antiapoptotic gene seladin-1 and octreotide-induced apoptosis in growth hormone-secreting and nonfunctioning pituitary adenomas.
Adenoma
Expression Profiling of Proliferation and Apoptotic Markers along the Adenoma-Carcinoma Sequence in Familial Adenomatous Polyposis Patients.
Adenoma
Fish fatty acids alter markers of apoptosis in colorectal adenoma and adenocarcinoma cell lines but fish consumption has no impact on apoptosis-induction ex vivo.
Adenoma
Identifying cancer-related molecular targets of Nandina domestica Thunb. by network pharmacology-based analysis in combination with chemical profiling and molecular docking studies.
Adenoma
Immunoexpression of the COX-2, p53, and caspase-3 proteins in colorectal adenoma and non-neoplastic mucosa.
Adenoma
Inhibition of intestinal tumorigenesis in apc(min/+) mice by green tea polyphenols (polyphenon e) and individual catechins.
Adenoma
Luteinizing Hormone and GATA4 Action in the Adrenocortical Tumorigenesis of Gonadectomized Female Mice.
Adenoma
Mutant K-ras promotes carcinogen-induced murine colorectal tumourigenesis, but does not alter tumour chromosome stability.
Adenoma
Suppression of familial adenomatous polyposis by CP-31398, a TP53 modulator, in APCmin/+ mice.
Adenoma
The pattern of CPP32/caspase-3 expression reflects the biological behavior of the human pancreatic duct cell tumors.
Adenoma
TRAIL induces apoptosis in human colorectal adenoma cell lines and human colorectal adenomas.
Adenoma
Use of mitogenic cascade blockers for treatment of C-Raf induced lung adenoma in vivo: CI-1040 strongly reduces growth and improves lung structure.
Adenoma
[Expression of AIF and caspase-3 in colorectal carcinoma, adenoma, and normal mucosa and its correlation]
Adenoma, Oxyphilic
Caspase 3 as a Novel Marker to Distinguish Chromophobe Renal Cell Carcinoma from Oncocytoma.
Adenomatous Polyposis Coli
BNIP3L-mediated mitophagy is required for mitochondrial remodeling during the differentiation of optic nerve oligodendrocytes.
Adenomatous Polyposis Coli
Structure of the USP15 N-Terminal Domains: A ?-Hairpin Mediates Close Association between the DUSP and UBL Domains.
Adenomatous Polyposis Coli
Suppression of glial activation is involved in the protection of IL-10 on maternal E. coli induced neonatal white matter injury.
Adenomatous Polyps
Melanosis coli sparing adenomatous polyps: novel findings using cleaved caspase-3 immunohistochemistry.
Adrenal Cortex Neoplasms
Bitter Melon (Momordica charantia) Extract Suppresses Adrenocortical Cancer Cell Proliferation Through Modulation of the Apoptotic Pathway, Steroidogenesis, and Insulin-Like Growth Factor Type 1 Receptor/RAC-? Serine/Threonine-Protein Kinase Signaling.
Adrenocortical Carcinoma
Livin/BIRC7 expression as malignancy marker in adrenocortical tumors.
African Swine Fever
African swine fever virus IAP-like protein induces the activation of nuclear factor kappa B.
Aggressive Periodontitis
Expression of caspase-3, p53 and Bcl-2 in generalized aggressive periodontitis.
Albuminuria
Apocynin attenuates tubular apoptosis and tubulointerstitial fibrosis in transgenic mice independent of hypertension.
Albuminuria
Astragaloside IV, a novel antioxidant, prevents glucose-induced podocyte apoptosis in vitro and in vivo.
Albuminuria
Caspase-3 Promotes Diabetic Kidney Disease Through Gasdermin E-Mediated Progression to Secondary Necrosis During Apoptosis.
Albuminuria
Specific endothelial heparin-binding EGF-like growth factor deletion ameliorates renal injury induced by chronic angiotensin II infusion.
Alexander Disease
Alexander disease causing mutations in the C-terminal domain of GFAP are deleterious both to assembly and network formation with the potential to both activate caspase 3 and decrease cell viability.
Alopecia
Inhibitory effect of M50054, a novel inhibitor of apoptosis, on anti-Fas-antibody-induced hepatitis and chemotherapy-induced alopecia.
Alopecia
Serenoa repens extracts promote hair regeneration and repair of hair loss mouse models by activating TGF-? and mitochondrial signaling pathway.
Alzheimer Disease
Activation of caspase-3 in single neurons and autophagic granules of granulovacuolar degeneration in Alzheimer's disease. Evidence for apoptotic cell death.
Alzheimer Disease
Active caspase-6 and caspase-6-cleaved tau in neuropil threads, neuritic plaques, and neurofibrillary tangles of Alzheimer's disease.
Alzheimer Disease
Alpha-fodrin is cleaved by caspase-3 in a chronic ocular hypertensive (COH) rat model of glaucoma.
Alzheimer Disease
Alteration of proteins regulating apoptosis, Bcl-2, Bcl-x, Bax, Bak, Bad, ICH-1 and CPP32, in Alzheimer's disease.
Alzheimer Disease
Alterations in behavior, amyloid beta-42, caspase-3, and Cox-2 in mutant PS2 transgenic mouse model of Alzheimer's disease.
Alzheimer Disease
Alzheimer's disease cybrids replicate beta-amyloid abnormalities through cell death pathways.
Alzheimer Disease
Antagonistic effects of Ultra-Low-Molecular-Weight Heparin on A?25-35-induced apoptosis in cultured rat cortical neurons.
Alzheimer Disease
Astrocytes secrete exosomes enriched with proapoptotic ceramide and prostate apoptosis response 4 (PAR-4): potential mechanism of apoptosis induction in Alzheimer disease (AD).
Alzheimer Disease
C-terminal fragments of amyloid precursor proteins increase cofilin phosphorylation by LIM kinase in cultured rat primary neurons.
Alzheimer Disease
CASP3 and LDOC-1 gene expression in a patient with carcinoma in the hairy part of the head skin and Alzheimer disease.
Alzheimer Disease
Caspase activation in the limbic cortex of subjects with early Alzheimer's disease.
Alzheimer Disease
Caspase-3 activation as a bifurcation point between plasticity and cell death.
Alzheimer Disease
Caspase-3 cleavage of GGA3 stabilizes BACE: implications for Alzheimer's disease.
Alzheimer Disease
Caspase-3 cleaved spectrin colocalizes with neurofilament-immunoreactive neurons in Alzheimer's disease.
Alzheimer Disease
Caspase-3 is enriched in postsynaptic densities and increased in Alzheimer's disease.
Alzheimer Disease
Caspase-3 triggers early synaptic dysfunction in a mouse model of Alzheimer's disease.
Alzheimer Disease
Caspase-cleaved amyloid precursor protein and activated caspase-3 are co-localized in the granules of granulovacuolar degeneration in Alzheimer's disease and Down's syndrome brain.
Alzheimer Disease
Caspase-cleaved TAR DNA-binding protein-43 is a major pathological finding in Alzheimer's disease.
Alzheimer Disease
Characterization of hippocampal Cajal-Retzius cells during development in a mouse model of Alzheimer's disease (Tg2576).
Alzheimer Disease
Characterization of TauC3 antibody and demonstration of its potential to block tau propagation.
Alzheimer Disease
CXCL1 Triggers Caspase-3 Dependent Tau Cleavage in Long-Term Neuronal Cultures and in the Hippocampus of Aged Mice: Implications in Alzheimer's Disease.
Alzheimer Disease
Decreased levels of PSD95 and two associated proteins and increased levels of BCl(2) and caspase 3 in hippocampus from subjects with amnestic mild cognitive impairment: Insights into their potential roles for loss of synapses and memory, accumulation of Abeta, and neurodegeneration in a prodromal stage of Alzheimer's disease.
Alzheimer Disease
Detection of Active Caspase-3 in Mouse Models of Stroke and Alzheimer's Disease with a Novel Dual Positron Emission Tomography/Fluorescent Tracer [68Ga]Ga-TC3-OGDOTA.
Alzheimer Disease
Different effects of anesthetic isoflurane on caspase-3 activation and cytosol cytochrome c levels between mice neural progenitor cells and neurons.
Alzheimer Disease
Dysregulation of Autophagy, Mitophagy, and Apoptosis Genes in the CA3 Region of the Hippocampus in the Ischemic Model of Alzheimer's Disease in the Rat.
Alzheimer Disease
Effect of antibodies to glutamate on caspase-3 activity in brain structures of rats with experimental Alzheimer's disease.
Alzheimer Disease
Erratum to: CASP3 and LDOC-1 gene expression in a patient with carcinoma in the hairy part of the head skin and Alzheimer disease.
Alzheimer Disease
Expression of transcription factors c-Fos, c-Jun, CREB-1 and ATF-2, and caspase-3 in relation with abnormal tau deposits in Pick's disease.
Alzheimer Disease
Gamma secretase-activating protein is a substrate for caspase-3: implications for Alzheimer's disease.
Alzheimer Disease
Glia maturation factor overexpression in neuroblastoma cells activates glycogen synthase kinase-3beta and caspase-3.
Alzheimer Disease
Hyperphosphorylated truncated protein tau induces caspase-3 independent apoptosis-like pathway in the Alzheimer's Disease cellular model.
Alzheimer Disease
Implication of Caspase-3 as a Common Therapeutic Target for Multineurodegenerative Disorders and Its Inhibition Using Nonpeptidyl Natural Compounds.
Alzheimer Disease
In situ immunodetection of neuronal caspase-3 activation in Alzheimer disease.
Alzheimer Disease
Influence of Early Life Lead (Pb) Exposure on ?-Synuclein, GSK-3? and Caspase-3 Mediated Tauopathy: Implications on Alzheimer's Disease.
Alzheimer Disease
Intermolecular association between caspase-mediated cleavage fragments of phospholipase D1 protects against apoptosis.
Alzheimer Disease
Involvement of caspases in proteolytic cleavage of Alzheimer's amyloid-beta precursor protein and amyloidogenic A beta peptide formation.
Alzheimer Disease
Isoflurane induces endoplasmic reticulum stress and caspase activation through ryanodine receptors.
Alzheimer Disease
Methylglyoxal reduces mitochondrial potential and activates Bax and caspase-3 in neurons: Implications for Alzheimer's disease.
Alzheimer Disease
MicroRNA Let-7f-5p Promotes Bone Marrow Mesenchymal Stem Cells Survival by Targeting Caspase-3 in Alzheimer Disease Model.
Alzheimer Disease
N-methyl-D-aspartate receptor and apoptosis in Alzheimer's disease and multiinfarct dementia.
Alzheimer Disease
Neuron loss in the 5XFAD mouse model of Alzheimer's disease correlates with intraneuronal A?42 accumulation and Caspase-3 activation.
Alzheimer Disease
Nitric oxide and cell signaling: in vivo evaluation of NO-dependent apoptosis by MRI and not NMR techniques.
Alzheimer Disease
Nmnat1 Modulates Mitochondrial Oxidative Stress by Inhibiting Caspase-3 Signaling in Alzheimer's Disease.
Alzheimer Disease
Ochratoxin A-induced genotoxic and epigenetic mechanisms lead to Alzheimer disease: its modulation with strategies.
Alzheimer Disease
Optimized liposomes with transactivator of transcription peptide and anti-apoptotic drugs to target hippocampal neurons and prevent tau-hyperphosphorylated neurodegeneration.
Alzheimer Disease
Proteolytic cleavage of polymeric tau protein by caspase-3: implications for Alzheimer disease.
Alzheimer Disease
Regulation of gamma-secretase activating protein by the 5Lipoxygenase: in vitro and in vivo evidence.
Alzheimer Disease
Role of caspase-3 in tau truncation at D421 is restricted in transgenic mouse models for tauopathies.
Alzheimer Disease
SET protein (TAF1beta, I2PP2A) is involved in neuronal apoptosis induced by an amyloid precursor protein cytoplasmic subdomain.
Alzheimer Disease
Staurosporine-induced activation of caspase-3 is potentiated by presenilin 1 familial Alzheimer's disease mutations in human neuroglioma cells.
Alzheimer Disease
Synthesis of new 3-alkoxy-7-amino-4-chloro-isocoumarin derivatives as new beta-amyloid peptide production inhibitors and their activities on various classes of protease.
Alzheimer Disease
The Ayurvedic plant Bacopa monnieri inhibits inflammatory pathways in the brain.
Alzheimer Disease
The effect of intracerebroventricular injection of beta amyloid peptide (1-42) on caspase-3 activity, lipid peroxidation, nitric oxide and NOS expression in young adult and aged rat brain.
Alzheimer Disease
The effect of vitamin B12 on synaptic plasticity of hippocampus in Alzheimer's disease model rats.
Alzheimer Disease
The role of platelet activating factor in prion and amyloid-beta neurotoxicity.
Alzheimer Disease
The silent information regulator 1 pathway attenuates ROS-induced oxidative stress in Alzheimer's disease.
Alzheimer Disease
Wild-type but not FAD mutant presenilin-1 prevents neuronal degeneration by promoting phosphatidylinositol 3-kinase neuroprotective signaling.
Alzheimer Disease
[Effect of TX0201 on expression of the apoptosis signal transduction molecule caspase-3 and apoptosis associated genes bcl-2 and bax mRNA in brain tissue of rat analogue model of Alzheimer's disease]
Alzheimer Disease
[Effects of qingxin kaiqiao recipe volatile oil on expressions of GFAP and caspase-3 in the cortex and hippocampus of AD rats].
Alzheimer Disease
[Effects of tanshinone IIA on the expressions of caspase-3, Akt and NF-?B in the brains of rat models of Alzheimer's disease].
Alzheimer Disease
[Effects of Valeriana amurensis on the expressions of beta-APP, Abeta(1-40) and caspase-3 in Alzheimer's disease model rat's brain]
Alzheimer Disease
[Electroacupuncture improves learning-memory ability possibly by suppressing apoptosis and down-regulating expression of apoptosis-related proteins in hippocampus and cerebral cortex in immature mice with Alzheimer's disease].
Alzheimer Disease
[Neuroprotective effect of ginsenoside Rb-1 on a rat model of Alzheimer's disease].
Ameloblastoma
Differential expression of apoptosis-related proteins in various cellular components of ameloblastomas.
Ameloblastoma
Immunohistochemical analysis of apoptosis-related factors (Fas, Fas ligand, caspase-3 and single-stranded DNA) in ameloblastomas.
Ameloblastoma
Role of HIF-1? and CASPASE-3 in cystogenesis of odontogenic cysts and tumors.
Amyloidosis
4'-iodo-4'-deoxydoxorubicin and tetracyclines disrupt transthyretin amyloid fibrils in vitro producing noncytotoxic species: screening for TTR fibril disrupters.
Amyloidosis
Selected nutraceutic screening by therapeutic effects on doxorubicin-induced chronic kidney disease.
Amyotrophic Lateral Sclerosis
Caspase-3 cleaves and inactivates the glutamate transporter EAAT2.
Amyotrophic Lateral Sclerosis
Dissociation between neurodegeneration and caspase-11-mediated activation of caspase-1 and caspase-3 in a mouse model of amyotrophic lateral sclerosis.
Amyotrophic Lateral Sclerosis
Elevated caspase 3 activity and cytosolic cytochrome c in NT2 cybrids containing amyotrophic lateral sclerosis subject mtDNA.
Amyotrophic Lateral Sclerosis
Identification and verification of key genes in varicocele rats through high-throughput sequencing and bioinformatics analysis.
Amyotrophic Lateral Sclerosis
Implication of Caspase-3 as a Common Therapeutic Target for Multineurodegenerative Disorders and Its Inhibition Using Nonpeptidyl Natural Compounds.
Amyotrophic Lateral Sclerosis
Induction of proinflammatory molecules in mice with amyotrophic lateral sclerosis: no requirement for proapoptotic interleukin-1beta in neurodegeneration.
Amyotrophic Lateral Sclerosis
MAPT (Tau) expression is a biomarker for an increased rate of survival in pediatric neuroblastoma.
Amyotrophic Lateral Sclerosis
Neuroprotective effects of novel nitrones: In vitro and in silico studies.
Amyotrophic Lateral Sclerosis
PTK2/FAK regulates UPS impairment via SQSTM1/p62 phosphorylation in TARDBP/TDP-43 proteinopathies.
Amyotrophic Lateral Sclerosis
Retinoic acid worsens ATG10-dependent autophagy impairment in TBK1-mutant hiPSC-derived motoneurons through SQSTM1/p62 accumulation.
Amyotrophic Lateral Sclerosis
The VPAC2 agonist peptide histidine isoleucine (PHI) up-regulates glutamate transport in the corpus callosum of a rat model of amyotrophic lateral sclerosis (hSOD1G93A) by inhibiting caspase-3 mediated inactivation of GLT-1a.
Anemia
Erythroid expansion and survival in response to acute anemia stress: the role of EPO receptor, GATA-1, Bcl-xL and caspase-3.
Anemia
Evidence of parvovirus B19 infection in patients of pre-eclampsia and eclampsia with dyserythropoietic anaemia.
Anemia, Aplastic
Primitive Sca-1 Positive Bone Marrow HSC in Mouse Model of Aplastic Anemia: A Comparative Study through Flowcytometric Analysis and Scanning Electron Microscopy.
Anemia, Refractory
Increased caspase-3 activity in refractory anemias: lack of evidence for Fas pathway implication.
Anemia, Refractory, with Excess of Blasts
Activity of the caspase-3/CPP32 enzyme is increased in "early stage" myelodysplastic syndromes with excessive apoptosis, but caspase inhibition does not enhance colony formation in vitro.
Aneurysm
Inhibition of caspase-3 differentially affects vascular smooth muscle cell apoptosis in the concave versus convex aortic sites in ascending aneurysms with a bicuspid aortic valve.
Aneurysm
The potential role of Neutrophil Gelatinase-Associated Lipocalin (NGAL) in the development of abdominal aortic aneurysms.
Angiomyolipoma
Human TSC-associated renal angiomyolipoma cells are hypersensitive to ER stress.
Aortic Aneurysm
Inhibition of caspase-3 differentially affects vascular smooth muscle cell apoptosis in the concave versus convex aortic sites in ascending aneurysms with a bicuspid aortic valve.
Aortic Aneurysm, Thoracic
Antiapoptotic Effect of ?1 Blockers in Ascending Thoracic Aortic Smooth Muscle Cells: The Role of HSP70 Expression.
Aortic Valve Stenosis
Antiapoptotic Effect of ?1 Blockers in Ascending Thoracic Aortic Smooth Muscle Cells: The Role of HSP70 Expression.
Arrhythmias, Cardiac
Huangzhi Oral Liquid Prevents Arrhythmias by Upregulating Caspase-3 and Apoptosis Network Proteins in Myocardial Ischemia-Reperfusion Injury in Rats.
Arrhythmias, Cardiac
Impact of citrate pretreatment on ventricular arrhythmia and myocardial capase-3 expression in ischemia/reperfusion injury.
Arthritis
Chondroitin-4-sulphate inhibits NF-kB translocation and caspase activation in collagen-induced arthritis in mice.
Arthritis
Secretory lysosomes of mouse mast cells store and exocytose active caspase-3 in a strictly granzyme B dependent manner.
Arthritis
[Up-regulations of Bax and caspase-3 and down-regulation of Bcl-2 after Xinfeng capsule treatment in adjuvant-induced arthritis rats].
Arthritis, Experimental
7,3'-dimethoxy hesperetin induces apoptosis of fibroblast-like synoviocytes in rats with adjuvant arthritis through caspase 3 activation.
Arthritis, Experimental
Inhibition of nitric oxide and caspase-3 mediated apoptosis by a tetrapeptide derivative (PEP1261) in cultured synovial fibroblasts from collagen-induced arthritis.
Arthritis, Rheumatoid
Bee venom induces apoptosis through caspase-3 activation in synovial fibroblasts of patients with rheumatoid arthritis.
Arthritis, Rheumatoid
Immunohistochemistry of programmed cell death in archival human pathology specimens.
Arthritis, Rheumatoid
Increased baseline RUNX2, caspase 3 and p21 gene expressions in the peripheral blood of disease-modifying anti-rheumatic drug-naïve rheumatoid arthritis patients are associated with improved clinical response to methotrexate therapy.
Arthritis, Rheumatoid
[Inhibitory effect of resveratrol on the proliferation of synoviocytes in rheumatoid arthritis and its mechanism in vitro]
Ascorbic Acid Deficiency
Dietary vitamin C deficiency depressed the gill physical barriers and immune barriers referring to Nrf2, apoptosis, MLCK, NF-?B and TOR signaling in grass carp (Ctenopharyngodon idella) under infection of Flavobacterium columnare.
Ascorbic Acid Deficiency
Dietary vitamin C deficiency depresses the growth, head kidney and spleen immunity and structural integrity by regulating NF-?B, TOR, Nrf2, apoptosis and MLCK signaling in young grass carp (Ctenopharyngodon idella).
Asthenozoospermia
Attenuation of aquaporin-3 may be contributing to low sperm motility and is associated with activated caspase-3 in asthenozoospermic individuals.
Asthenozoospermia
Quantitative study of caspase-3 activity in semen and after swim-up preparation in relation to sperm quality.
Asthma
Antigen-binding characteristics of circulating IgG autoantibodies to cytokeratin 18 protein in patients with nonallergic asthma.
Asthma
Antigen-induced airway hyperresponsiveness and obstruction is related to caveolin-1 expression in airway smooth muscle in a guinea pig asthma model.
Asthma
Apoptosis in the normal and inflamed airway epithelium: role of zinc in epithelial protection and procaspase-3 regulation.
Asthma
CD11b+ and Sca-1+ Cells Exert the Main Beneficial Effects of Systemically Administered Bone Marrow-Derived Mononuclear Cells in a Murine Model of Mixed Th2/Th17 Allergic Airway Inflammation.
Asthma
Combined Extracts of Epimedii Folium and Ligustri Lucidi Fructus with Budesonide Attenuate Airway Remodeling in the Asthmatic Rats by Regulating Apoptosis and Autophagy.
Asthma
House dust mite-induced asthma causes oxidative damage and DNA double-strand breaks in the lungs.
Asthma
Secretory lysosomes of mouse mast cells store and exocytose active caspase-3 in a strictly granzyme B dependent manner.
Asthma
[Evaluating the activity of the apoptosis-regulating genes from Bcl-2, Bax expression, and caspase-3 activity in bronchial epithelial cells in patients with asthma].
Astrocytoma
A key role for caspase-2 and caspase-3 in the apoptosis induced by 2-chloro-2'-deoxy-adenosine (cladribine) and 2-chloro-adenosine in human astrocytoma cells.
Astrocytoma
A Study to Investigate the Role of GULP/ CED 6 Gene in "Eat Me" Signaling in Cellular Efferocytosis and Immunosurveillance.
Astrocytoma
Association of TP53 mutation, p53 overexpression, and p53 codon 72 polymorphism with susceptibility to apoptosis in adult patients with diffuse astrocytomas.
Astrocytoma
Co-localization of PCNA, VCAM-1 and caspase-3 with nestin in xenografts derived from human anaplastic astrocytoma and glioblastoma multiforme tumor spheres.
Astrocytoma
Differential PARP cleavage: an indication for existence of multiple forms of cell death in human gliomas.
Astrocytoma
Increased expression of stefin B in the nucleus of T98G astrocytoma cells delays caspase activation.
Astrocytoma
Memantine and Ibuprofen pretreatment exerts anti-inflammatory effect against streptozotocin-induced astroglial inflammation via modulation of NMDA receptor-associated downstream calcium ion signaling.
Astrocytoma
P2Y6 nucleotide receptor activates PKC to protect 1321N1 astrocytoma cells against tumor necrosis factor-induced apoptosis.
Astrocytoma
p38? MAPK affords cytoprotection against oxidative stress-induced astrocyte apoptosis via induction of ?B-crystallin and its anti-apoptotic function.
Astrocytoma
Survivin, caspase-3 and MIB-1 expression in astrocytic tumors of various grades.
Ataxia
Curcumin protects purkinje neurons, ameliorates motor function and reduces cerebellar atrophy in rat model of cerebellar ataxia induced by 3-AP.
Ataxia
Investigation of the Anticancer Mechanism of Isoorientin Isolated from Eremurus Spectabilis Leaves via Cell Cycle Pathways in HT-29 Human Colorectal Adenocarcinoma Cells.
Ataxia
Patterns of fractional anisotropy changes in white matter of cerebellar peduncles distinguish spinocerebellar ataxia-1 from multiple system atrophy and other ataxia syndromes.
Ataxia
Relationship between ataxin-1 nuclear inclusions and Purkinje cell specific proteins in SCA-1 transgenic mice.
Ataxia
Rosiglitazone Synergizes the Neuroprotective Effects of Valproic Acid Against Quinolinic Acid-Induced Neurotoxicity in Rats: Targeting PPAR? and HDAC Pathways.
Ataxia Telangiectasia
A Novel Oral Astaxanthin Nanoemulsion from Haematococcus pluvialis Induces Apoptosis in Lung Metastatic Melanoma.
Ataxia Telangiectasia
Beta-Ecdysone Protects Mouse Osteoblasts from Glucocorticoid-Induced Apoptosis In Vitro.
Ataxia Telangiectasia
Caspase-3 knockout attenuates radiation-induced tumor repopulation via impairing the ATM/p53/Cox-2/PGE2 pathway in non-small cell lung cancer.
Ataxia Telangiectasia
Down-expression of poly(ADP-ribose) polymerase in p53-regulated pancreatic cancer cells.
Ataxia Telangiectasia
Epigenetic inactivation of BCL6B, a novel functional tumour suppressor for gastric cancer, is associated with poor survival of gastric cancer.
Ataxia Telangiectasia
JS-K, a nitric oxide prodrug, induces DNA damage and apoptosis in HBV-positive hepatocellular carcinoma HepG2.2.15 cell.
Ataxia Telangiectasia
Preclinical evaluation of a novel SIRT1 modulator SRT1720 in multiple myeloma cells.
Ataxia Telangiectasia
Protective effects of Korean red ginseng against radiation-induced apoptosis in human HaCaT keratinocytes.
Ataxia Telangiectasia
S-phase checkpoints regulate Apo2 ligand/TRAIL and CPT-11-induced apoptosis of prostate cancer cells.
Ataxia Telangiectasia
Tannic Acid Induces the Mitochondrial Pathway of Apoptosis and S Phase Arrest in Porcine Intestinal IPEC-J2 Cells.
Ataxia Telangiectasia
Tetrandrine Enhances H2O2-Induced Apoptotic Cell Death Through Caspase-dependent Pathway in Human Keratinocytes.
Ataxia Telangiectasia
Trovafloxacin-induced replication stress sensitizes HepG2 cells to tumor necrosis factor-alpha-induced cytotoxicity mediated by extracellular signal-regulated kinase and ataxia telangiectasia and Rad3-related.
Ataxia Telangiectasia
Unraveling the in vitro antitumor activity of Vismia baccifera against HepG2: role of hydrogen peroxide.
Atherosclerosis
5-Aminolevulinic Acid-Mediated Sonodynamic Therapy Inhibits RIPK1/RIPK3-Dependent Necroptosis in THP-1-Derived Foam Cells.
Atherosclerosis
Caspase-3 Deletion Promotes Necrosis in Atherosclerotic Plaques of ApoE Knockout Mice.
Atherosclerosis
Colocalization of CPP-32 with apoptotic cells in human atherosclerotic plaques.
Atherosclerosis
Disocin prevents postmenopausal atherosclerosis in ovariectomized LDLR-/- mice through a PGC-1?/ER? pathway leading to promotion of autophagy and inhibition of oxidative stress, inflammation and apoptosis.
Atherosclerosis
Inhibitory Effects of Ginsenoside Rb1 on Early Atherosclerosis in ApoE-/- Mice via Inhibition of Apoptosis and Enhancing Autophagy.
Atherosclerosis
MiR-106b-5p Inhibits Tumor Necrosis Factor-?-induced Apoptosis by Targeting Phosphatase and Tensin Homolog Deleted on Chromosome 10 in Vascular Endothelial Cells.
Atherosclerosis
miR-30c-5p regulates macrophage-mediated inflammation and pro-atherosclerosis pathways.
Atherosclerosis
Noncanonical inhibition of caspase-3 by a nuclear microRNA confers endothelial protection by autophagy in atherosclerosis.
Atherosclerosis
Oxidized low-density lipoprotein induces apoptosis of human endothelial cells by activation of CPP32-like proteases. A mechanistic clue to the 'response to injury' hypothesis.
Atherosclerosis
Poly(ADP-ribose) Polymerase (PARP) and PARP Inhibitors: Mechanisms of Action and Role in Cardiovascular Disorders.
Atherosclerosis
Quantitative analysis of the expression of caspase 3 and caspase 9 in different types of atherosclerotic lesions in the human aorta.
Atherosclerosis
Quercetin attenuates high fructose feeding-induced atherosclerosis by suppressing inflammation and apoptosis via ROS-regulated PI3K/AKT signaling pathway.
Atherosclerosis
Role of macrophage and smooth muscle cell apoptosis in association with oxidized low-density lipoprotein in the atherosclerotic development.
Atherosclerosis
Superoxide is a potential culprit of caspase-3 dependent endothelial cell death induced by lysophosphatidylcholine.
Atherosclerosis
The association between plasma caspase-3, atherosclerosis, and vascular function in the Dallas Heart Study.
Atherosclerosis
TRPC1/TRPC3 channels mediate lysophosphatidylcholine-induced apoptosis in cultured human coronary artery smooth muscles cells.
Atrial Fibrillation
CASP3 genetic variants and susceptibility to atrial fibrillation in Chinese Han population.
Atrial Fibrillation
Suppression of persistent atrial fibrillation by genetic knockdown of caspase 3: a pre-clinical pilot study.
Atrial Fibrillation
[Calpain-I, calpastatin, caspase-3 and apoptosis in the human left atrium in rheumatic atrial fibrillation]
Autoimmune Diseases
Foxp3 expression in liver correlates with the degree but not the cause of inflammation.
Autoimmune Diseases
High glucose concentration in T1D patients modulates apoptotic protein expression: Down regulation of BAX and FAS and up regulation of XIAP.
Autoimmune Diseases
Identification of the primary caspase 3 cleavage site in alpha II-spectrin during apoptosis.
Azoospermia
Caspase-3 and VEGF immunopositivity in seminiferous tubule germ cells in cases of obstructive and non-obstructive azoospermia in smokers versus non-smokers.
Azoospermia
Status of the executioner step of apoptosis in human with normal spermatogenesis and azoospermia.
Bacteremia
Alcohol impairs the myeloid proliferative response to bacteremia in mice by inhibiting the stem cell antigen-1/ERK pathway.
Bacteremia
Impairment of Hematopoietic Precursor Cell Activation during the Granulopoietic Response to Bacteremia in Mice with Chronic-Plus-Binge Alcohol Administration.
Bacteremia
Toll-like receptor 4/stem cell antigen 1 signaling promotes hematopoietic precursor cell commitment to granulocyte development during the granulopoietic response to Escherichia coli bacteremia.
Bacteremia
Vancomycin Is Protective in a Neonatal Mouse Model of Staphylococcus epidermidis-Potentiated Hypoxic-Ischemic Brain Injury.
Bacterial Infections
Apoptosis of human gastric epithelial cells via caspase-3 activation in response to Helicobacter pylori infection: possible involvement of neutrophils through tumor necrosis factor alpha and soluble Fas ligands.
Bacterial Infections
C4b-Binding Protein Deposition is Induced in Diseased Aortic Heart Valves, Coinciding with C3d.
Bacterial Infections
Caspase -1, -3, -8 and antioxidant enzyme genes are key molecular effectors following Vibrio parahaemolyticus and Aeromonas veronii infection in fish leukocytes.
Bacterial Infections
Characterization and functional analysis of a caspase 3 gene: Evidence that ChCas 3 participates in the regulation of apoptosis in Crassostrea hongkongensis.
Bacterial Infections
Glucose-6-phosphate dehydrogenase (G6PD)-deficient epithelial cells are less tolerant to infection by Staphylococcus aureus.
Bacterial Infections
Porcine caspase-3: its cloning and activity during apoptosis of PK15 cells induced by porcine Fas ligand.
Bacterial Infections
Targeted peptidecentric proteomics reveals caspase-7 as a substrate of the caspase-1 inflammasomes.
Barrett Esophagus
Expression of survivin, p53, and caspase 3 in Barrett's esophagus carcinogenesis.
Barrett Esophagus
Expression of the bile acid receptor FXR in Barrett's esophagus and enhancement of apoptosis by guggulsterone in vitro.
Barth Syndrome
Deficiency in Cardiolipin Reduces Doxorubicin-Induced Oxidative Stress and Mitochondrial Damage in Human B-Lymphocytes.
beta-Thalassemia
Derangement of erythrocytic AE1 in beta-thalassemia by caspase 3: pathogenic mechanisms and implications in red blood cell senescence.
Bicuspid Aortic Valve Disease
Inhibition of caspase-3 differentially affects vascular smooth muscle cell apoptosis in the concave versus convex aortic sites in ascending aneurysms with a bicuspid aortic valve.
Biliary Atresia
Temporal-spatial activation of apoptosis and epithelial injury in murine experimental biliary atresia.
Blast Crisis
Chaetocin antileukemia activity against chronic myelogenous leukemia cells is potentiated by bone marrow stromal factors and overcomes innate imatinib resistance.
Blast Crisis
Effects of the bcr/abl kinase inhibitors AG957 and NSC 680410 on chronic myelogenous leukemia cells in vitro.
Blister
Blebbistatin Modulates Prostatic Cell Growth and Contractility through Myosin II Signaling.
Blister
Caspase-3-mediated cleavage of ROCK I induces MLC phosphorylation and apoptotic membrane blebbing.
Blister
Delayed cell death related to acute cerebral blood flow changes following subarachnoid hemorrhage in the rat brain.
Blister
Feasibility study for clinical application of caspase-3 inhibitors in Pemphigus vulgaris.
Blister
Increased Activity and Apoptosis of Eosinophils in Blister Fluids, Skin and Peripheral Blood of Patients with Bullous Pemphigoid.
Blister
Induction of apoptosis in starfish eggs requires spontaneous inactivation of MAPK (extracellular signal-regulated kinase) followed by activation of p38MAPK.
Blister
Macrophage-mediated transfer of cancer-derived components to stromal cells contributes to establishment of a pro-tumor microenvironment.
Blister
Tumour-suppressive effect of oestrogen receptor ? in colorectal cancer patients, colon cancer cells, and a zebrafish model.
Bloom Syndrome
Cleavage of the Bloom's syndrome gene product during apoptosis by caspase-3 results in an impaired interaction with topoisomerase IIIalpha.
Bluetongue
Apoptosis and immuno-suppression in sheep infected with bluetongue virus serotype-23.
Bone Diseases, Metabolic
An Unbalanced Rearrangement of Chromosomes 4:20 is Associated with Childhood Osteoporosis and Reduced Caspase-3 Levels.
Bone Neoplasms
PLGA-carbon nanotube conjugates for intercellular delivery of caspase-3 into osteosarcoma cells.
Bone Resorption
Nuclear factor-kappaB-dependent mechanisms in breast cancer cells regulate tumor burden and osteolysis in bone.
Bone Resorption
Regulation of bone resorption and osteoclast survival by nitric oxide: possible involvement of NMDA-receptor.
Bone Resorption
The differential effects of the radioprotectant drugs amifostine and sodium selenite treatment in combination with radiation therapy on constituent bone cells, ewing's sarcoma of bone tumor cells, and rhabdomyosarcoma tumor cells in vitro.
Bone Resorption
The regulatory role of the RANKL/RANK/OPG signaling pathway in the mechanisms of tooth eruption in patients with impacted teeth.
Bone Resorption
[Expression of Caspase-3 and apoptosis in interface membranes of aseptically-loose total hip replacement]
Boutonneuse Fever
Changes of Bcl-2, Bax and Caspase-3 expression in the dermal microvascular endothelial cells and the epidermal layers of the eschar (tache noire) in patients with Mediterranean spotted fever.
Bradycardia
Mechanism in bradycardia induced by Trimethyltin chloride: Inhibition activity and expression of Na+/K+-ATPase and apoptosis in myocardia.
Brain Contusion
17Beta-estradiol differentially protects cortical pericontusional zone from programmed cell death after traumatic cerebral contusion at distinct stages via non-genomic and genomic pathways.
Brain Contusion
[The relationship of injury timing with the change of neuronal apoptosis and the expression of caspase-3 after brain contusion]
Brain Contusion
[The study on the expression of caspase-3 in experimental brain contusion in rats]
Brain Contusion
[Time-order expression of caspase-3 and iNOS in contused human brain tissue]
Brain Death
Donor Preconditioning After the Onset of Brain Death With Dopamine Derivate n-Octanoyl Dopamine Improves Early Posttransplant Graft Function in the Rat.
Brain Death
Duration of brain death and cold ischemia time, but not warm ischemia time, increases expression of genes associated with apoptosis in transplanted kidneys from deceased donors.
Brain Diseases
Apoptosis inhibition in ischemic brain by intraperitoneal PTD-BIR3-RING (XIAP).
Brain Diseases
Astrocytic and microglial response in experimentally induced diabetic rat brain.
Brain Diseases
Expression of caspase-3 in brains from paediatric patients with HIV-1 encephalitis.
Brain Diseases
Neuronal apoptosis is mediated by CXCL10 overexpression in simian human immunodeficiency virus encephalitis.
Brain Edema
Activation of the Melanocortin-1 Receptor by NDP-MSH Attenuates Oxidative Stress and Neuronal Apoptosis through PI3K/Akt/Nrf2 Pathway after Intracerebral Hemorrhage in Mice.
Brain Edema
Adrenomedullin Reduces Secondary Injury and Improves Outcome in Rats with Fluid Percussion Brain Injury.
Brain Edema
Apelin-13 protects the brain against ischemic reperfusion injury and cerebral edema in a transient model of focal cerebral ischemia.
Brain Edema
Astragaloside IV alleviates early brain injury following experimental subarachnoid hemorrhage in rats.
Brain Edema
Atorvastatin ameliorates early brain injury after subarachnoid hemorrhage via inhibition of AQP4 expression in rabbits.
Brain Edema
Autophagy activation is associated with neuroprotection against apoptosis via a mitochondrial pathway in a rat model of subarachnoid hemorrhage.
Brain Edema
Bakuchiol Attenuates Oxidative Stress and Neuron Damage by Regulating Trx1/TXNIP and the Phosphorylation of AMPK After Subarachnoid Hemorrhage in Mice.
Brain Edema
Carnosine Attenuates Brain Oxidative Stress and Apoptosis After Intracerebral Hemorrhage in Rats.
Brain Edema
Danhong Injection Combined With t-PA Improves Thrombolytic Therapy in Focal Embolic Stroke.
Brain Edema
Detrimental effects of post-treatment with fatty acids on brain injury in ischemic rats.
Brain Edema
Early Combined Therapy with Pharmacologically Induced Hypothermia and Edaravone Exerts Neuroprotective Effects in a Rat Model of Intracerebral Hemorrhage.
Brain Edema
Effects of low-dose unfractionated heparin on early brain injury after subarachnoid hemorrhage in mice.
Brain Edema
Ghrelin alleviates early brain injury after subarachnoid hemorrhage via the PI3K/Akt signaling pathway.
Brain Edema
Interleukin-10 mediates the neuroprotection of hyperbaric oxygen therapy against traumatic brain injury in mice.
Brain Edema
Isoflurane versus sevoflurane for early brain injury and expression of sphingosine kinase 1 after experimental subarachnoid hemorrhage.
Brain Edema
Ketogenic diet reduces cytochrome c release and cellular apoptosis following traumatic brain injury in juvenile rats.
Brain Edema
Melatonin attenuates early brain injury after subarachnoid hemorrhage by the JAK-STAT signaling pathway.
Brain Edema
Neuroprotective effect of erythropoietin after experimental cold injury-induced vasogenic brain edema in rats.
Brain Edema
Neuroprotective Effects of a Smoothened Receptor Agonist against Early Brain Injury after Experimental Subarachnoid Hemorrhage in Rats.
Brain Edema
Neuroprotective effects of hydrogen inhalation in an experimental rat intracerebral hemorrhage model.
Brain Edema
Neuroprotective effects of hydrogen sulfide against early brain injury and secondary cognitive deficits following subarachnoid hemorrhage.
Brain Edema
Neuroprotective Roles of l-Cysteine in Attenuating Early Brain Injury and Improving Synaptic Density via the CBS/H2S Pathway Following Subarachnoid Hemorrhage in Rats.
Brain Edema
Neurovascular protection reduces early brain injury after subarachnoid hemorrhage.
Brain Edema
Pioglitazone ameliorates neuronal damage after traumatic brain injury via the PPAR?/NF-?B/IL-6 signaling pathway.
Brain Edema
Platelet-Activating Factor Receptor (PAFR) plays a crucial role in experimental global cerebral ischemia and reperfusion.
Brain Edema
Poxvirus-derived cytokine response modifier A (CrmA) does not protect against focal cerebral ischemia in mice.
Brain Edema
Progesterone attenuates early brain injury after subarachnoid hemorrhage in rats.
Brain Edema
Protective effect of docosahexaenoic acid against brain injury in ischemic rats.
Brain Edema
Protective effect of quercetin against oxidative stress and brain edema in an experimental rat model of subarachnoid hemorrhage.
Brain Edema
Reduction of Autophagosome Overload Attenuates Neuronal Cell Death After Traumatic Brain Injury.
Brain Edema
Resveratrol Improves Mitochondrial Biogenesis Function and Activates PGC-1? Pathway in a Preclinical Model of Early Brain Injury Following Subarachnoid Hemorrhage.
Brain Edema
Role of c-Jun N-terminal kinase in early brain injury after subarachnoid hemorrhage.
Brain Edema
Sleep deprivation aggravates brain injury after experimental subarachnoid hemorrhage via TLR4-MyD88 pathway.
Brain Edema
Stereotactic Administration of Edaravone Ameliorates Collagenase-Induced Intracerebral Hemorrhage in Rat.
Brain Edema
Susceptibility to intracerebral hemorrhage-induced brain injury segregates with low aerobic capacity in rats.
Brain Edema
Therapeutic effects of L-Cysteine in newborn mice subjected to hypoxia-ischemia brain injury via the CBS/H2S system: Role of oxidative stress and endoplasmic reticulum stress.
Brain Edema
Uric Acid Neuroprotection Associated to IL-6/STAT3 Signaling Pathway Activation in Rat Ischemic Stroke.
Brain Infarction
Activation of caspase-3 in permanent and transient brain ischaemia in man.
Brain Infarction
Decrease in Oxidative Stress Parameters after Post-Ischaemic Recombinant Human Erythropoietin Administration in the Hippocampus of Rats Exposed to Focal Cerebral Ischaemia.
Brain Infarction
Downregulation of circular RNA HECTD1 induces neuroprotection against ischemic stroke through the microRNA-133b/TRAF3 pathway.
Brain Infarction
Graptopetalum paraguayense E. Walther leaf extracts protect against brain injury in ischemic rats.
Brain Infarction
Heme Oxygenase-1 Mediates Neuroprotection Conferred by Argon in Combination with Hypothermia in Neonatal Hypoxia-Ischemia Brain Injury.
Brain Infarction
Mild hypothermia modulates the expression of nestin and caspase-3 in the sub-granular zone and improves neurological outcomes in rats with ischemic stroke.
Brain Infarction
Multiple effects of 2ME2 and D609 on the cortical expression of HIF-1alpha and apoptotic genes in a middle cerebral artery occlusion-induced focal ischemia rat model.
Brain Infarction
Neuroprotective effect of ginkgetin in experimental cerebral ischemia/reperfusion via apoptosis inhibition and PI3K/Akt/mTOR signaling pathway activation.
Brain Infarction
Quercetin protects against cerebral ischemia/reperfusion and oxygen glucose deprivation/reoxygenation neurotoxicity.
Brain Infarction
The Antiapoptotic Actions of Mood Stabilizers: Molecular Mechanisms and Therapeutic Potentials.
Brain Infarction
The protective mechanism underlying total flavones of Dracocephalum (TFD) effects on rat cerebral ischemia reperfusion injury.
Brain Infarction
TNF-? Receptor Inhibitor Alleviates Metabolic and Inflammatory Changes in a Rat Model of Ischemic Stroke.
Brain Injuries
8-hydroxy-2-(di-n-propylamino)tetralin intervenes with neural cell apoptosis following diffuse axonal injury.
Brain Injuries
Anti-inflammatory effects of kaempferol-3-O-rhamnoside on HSV-1 encephalitis in vivo and in vitro.
Brain Injuries
Apoptosis has a prolonged role in the neurodegeneration after hypoxic ischemia in the newborn rat.
Brain Injuries
Brain mitochondrial uncoupling protein 2 (UCP2): a protective stress signal in neuronal injury.
Brain Injuries
Caspase inhibition by cardiotrophin-1 prevents neuronal death in vivo and in vitro.
Brain Injuries
Caspase-3 activation and caspase-like proteolytic activity in human perinatal hypoxic-ischemic brain injury.
Brain Injuries
Caspase-3 deficiency during development increases vulnerability to hypoxic-ischemic injury through caspase-3-independent pathways.
Brain Injuries
Clusterin contributes to caspase-3-independent brain injury following neonatal hypoxia-ischemia.
Brain Injuries
Correlation between neuronal injury and Caspase-3 after focal ischemia in human hippocampus.
Brain Injuries
Cortisol-induced immune suppression by a blockade of lymphocyte egress in traumatic brain injury.
Brain Injuries
Deletion of cellular prion protein results in reduced Akt activation, enhanced postischemic caspase-3 activation, and exacerbation of ischemic brain injury.
Brain Injuries
Dexamethasone-induced neuroprotection in hypoxic-ischemic brain injury in newborn rats is partly mediated via Akt activation.
Brain Injuries
Dual role of intrauterine immune challenge on neonatal and adult brain vulnerability to hypoxia-ischemia.
Brain Injuries
Effect of Sevoflurane postconditioning on gene expression in brain tissue of the middle cerebral artery occlusion rat model.
Brain Injuries
Effects of mild and moderate hypothemia therapy on expression of cerebral neuron apoptosis related proteins and glial fiber acidic protein after rat cardio-pulmonary resuscitation.
Brain Injuries
Enhanced autophagy contributes to excitotoxic lesions in a rat model of preterm brain injury.
Brain Injuries
Enhancement of endogenous neurogenesis in ephrin-B3 deficient mice after transient focal cerebral ischemia.
Brain Injuries
Ergostatrien-7,9(11),22-trien-3?-ol from Antrodia camphorata ameliorates ischemic stroke brain injury via downregulation of p65NF-?-B and caspase 3, and activation of Akt/GSK3/catenin-associated neurogenesis.
Brain Injuries
GSK3? inhibition protects the immature brain from hypoxic-ischaemic insult via reduced STAT3 signalling.
Brain Injuries
Immunohistochemical and biochemical assessment of caspase-3 activation and DNA fragmentation following transient focal ischemia in the rat.
Brain Injuries
Impairment of mitochondrial respiration after cerebral hypoxia-ischemia in immature rats: relationship to activation of caspase-3 and neuronal injury.
Brain Injuries
Inhibition of nNOS reduces ischemic cell death through down-regulating calpain and caspase-3 after experimental stroke.
Brain Injuries
Involvement of caspase-3 in cell death after hypoxia-ischemia declines during brain maturation.
Brain Injuries
Ischemic preconditioning reduces ischemic brain injury by suppressing nuclear factor kappa B expression and neuronal apoptosis.
Brain Injuries
Isoquercetin Improves Inflammatory Response in Rats Following Ischemic Stroke.
Brain Injuries
Kinetics of Apoptosis and Expression of Apoptosis-Related Proteins in Rat CA3 Hippocampus Cells After Experimental Diffuse Brain Injury.
Brain Injuries
Lack of X-linked inhibitor of apoptosis protein leads to increased apoptosis and tissue loss following neonatal brain injury.
Brain Injuries
Lactuside B decreases aquaporin-4 and caspase-3 mRNA expression in the hippocampus and striatum following cerebral ischaemia-reperfusion injury in rats.
Brain Injuries
Maternal exposure to LPS induces hypomyelination in the internal capsule and programmed cell death in the deep gray matter in newborn rats.
Brain Injuries
Mitochondrial E3 ubiquitin ligase 1 promotes brain injury by disturbing mitochondrial dynamics in a rat model of ischemic stroke.
Brain Injuries
Mitogen-activated protein kinase-activated protein (MAPKAP) kinase 2 deficiency protects brain from ischemic injury in mice.
Brain Injuries
N-tosyl-L-phenylalanyl-chloromethyl ketone eliminates the increase in caspase-3 and bcl-2 caused by brain injury in the newborn rat.
Brain Injuries
Necroptotic-Apoptotic Regulation in an Endothelin-1 Model of Cerebral Ischemia.
Brain Injuries
Neuronal apoptosis can be prevented by the combined therapy with melatonin and hypothermia in a neonatal rat model of hypoxic-ischemic encephalopathy.
Brain Injuries
Neuronal deficiency of hypoxia-inducible factor 2? increases hypoxic-ischemic brain injury in neonatal mice.
Brain Injuries
Neuroprotection against hypoxic-ischemic brain injury by inhibiting the apoptotic protease activating factor-1 pathway.
Brain Injuries
Neuroprotective effects of human umbilical cord-derived mesenchymal stem cells on periventricular leukomalacia-like brain injury in neonatal rats.
Brain Injuries
Osteopontin attenuates early brain injury through regulating autophagy-apoptosis interaction after subarachnoid hemorrhage in rats.
Brain Injuries
Overexpression of apoptosis inducing factor aggravates hypoxic-ischemic brain injury in neonatal mice.
Brain Injuries
Oxymatrine attenuated hypoxic-ischemic brain damage in neonatal rats via improving antioxidant enzyme activities and inhibiting cell death.
Brain Injuries
Peroxynitrite and caspase-3 expression after ischemia/reperfusion in mouse cardiac arrest model.
Brain Injuries
Possible involvement of cathepsin B/D and caspase-3 in deferoxamine-related neuroprotection of early brain injury after subarachnoid haemorrhage in rats.
Brain Injuries
Pressure-dependent effect of shock waves on rat brain: induction of neuronal apoptosis mediated by a caspase-dependent pathway.
Brain Injuries
Protective Effects of Chlorogenic Acid on Cerebral Ischemia/Reperfusion Injury Rats by Regulating Oxidative Stress-Related Nrf2 Pathway.
Brain Injuries
Purmorphamine Attenuates Neuro-Inflammation and Synaptic Impairments After Hypoxic-Ischemic Injury in Neonatal Mice via Shh Signaling.
Brain Injuries
Reduced nitric oxide is involved in prenatal ischemia-induced tolerance to neonatal hypoxic-ischemic brain injury in rats.
Brain Injuries
Selective, reversible caspase-3 inhibitor is neuroprotective and reveals distinct pathways of cell death after neonatal hypoxic-ischemic brain injury.
Brain Injuries
Sex differences in neonatal mouse brain injury after hypoxia-ischemia and adaptaquin treatment.
Brain Injuries
Simvastatin reduces caspase-3 activation and inflammatory markers induced by hypoxia-ischemia in the newborn rat.
Brain Injuries
Sulforaphane Protects Brains against Hypoxic-Ischemic Injury through Induction of Nrf2-Dependent Phase 2 Enzyme.
Brain Injuries
Susceptibility to intracerebral hemorrhage-induced brain injury segregates with low aerobic capacity in rats.
Brain Injuries
Systemic infusions of anti-interleukin-1? neutralizing antibodies reduce short-term brain injury after cerebral ischemia in the ovine fetus.
Brain Injuries
Tert-butylhydroquinone Ameliorates Early Brain Injury After Experimental Subarachnoid Hemorrhage in Mice by Enhancing Nrf2-Independent Autophagy.
Brain Injuries
Tetramethylpyrazine Protects against Early Brain Injury after Experimental Subarachnoid Hemorrhage by Affecting Mitochondrial-Dependent Caspase-3 Apoptotic Pathway.
Brain Injuries
The protective effect of rosuvastatin on ischemic brain injury and its mechanism.
Brain Injuries
TREATMENT WITH Z-LIGUSTILIDE, A COMPONENT OF ANGELICA SINENSIS, REDUCES BRAIN INJURY FOLLOWING A SUBARACHNOID HEMORRHAGE IN RATS.
Brain Injuries
Tumor necrosis factor-inducible gene 6 protein: A novel neuroprotective factor against inflammation-induced developmental brain injury.
Brain Injuries
[Expression of caspase-3 mRNA in the hippocampus of seven-day-old hypoxic-ischemic rats and the mechanism of neural protection with magnesium sulfate]
Brain Injuries
[Neuroprotection Mechanism of Lidocaine in Rabbits with Early Brain Injury Resulted from Subarachnoid Hemorrhage].
Brain Injuries
[Protection effect of recombiant human erythropoietin preconditioning against intrauterine hypoxic-ischemic brain injury and its influence on expression of caspase-3 protein in brain tissue].
Brain Injuries
[The study on the expression of caspase-3 in experimental brain contusion in rats]
Brain Injuries, Diffuse
Kinetics of Apoptosis and Expression of Apoptosis-Related Proteins in Rat CA3 Hippocampus Cells After Experimental Diffuse Brain Injury.
Brain Injuries, Traumatic
17beta-estradiol attenuates programmed cell death in cortical pericontusional zone following traumatic brain injury via upregulation of ERalpha and inhibition of caspase-3 activation.
Brain Injuries, Traumatic
A possible protective role of betain and omega-3 supplementation in traumatic brain injury.
Brain Injuries, Traumatic
Alpha II Spectrin breakdown products in immature Sprague Dawley rat hippocampus and cortex after traumatic brain injury.
Brain Injuries, Traumatic
Biomarkers Associated with the Outcome of Traumatic Brain Injury Patients.
Brain Injuries, Traumatic
Calpain and caspase proteolytic markers co-localize with rat cortical neurons after exposure to methamphetamine and MDMA.
Brain Injuries, Traumatic
Caspase inhibitor z-DEVD-fmk attenuates calpain and necrotic cell death in vitro and after traumatic brain injury.
Brain Injuries, Traumatic
Caspase-3 activity is present in cerebrospinal fluid from patients with traumatic brain injury.
Brain Injuries, Traumatic
Caspase-3 mediated neuronal death after traumatic brain injury in rats.
Brain Injuries, Traumatic
Clinical significance of alphaII-spectrin breakdown products in cerebrospinal fluid after severe traumatic brain injury.
Brain Injuries, Traumatic
Concurrent calpain and caspase-3 mediated proteolysis of alpha II-spectrin and tau in rat brain after methamphetamine exposure: a similar profile to traumatic brain injury.
Brain Injuries, Traumatic
Correlation research on the protein expression (p75NTR, bax, bcl-2, and caspase-3) and cortical neuron apoptosis following mechanical injury in rat.
Brain Injuries, Traumatic
Could NF-kappaB and caspase-3 be markers for estimation of post-interval of human traumatic brain injury?
Brain Injuries, Traumatic
Degradation of ?II-Spectrin Protein by Calpain-2 and Caspase-3 Under Neurotoxic and Traumatic Brain Injury Conditions.
Brain Injuries, Traumatic
Deletion of JDP2 improves neurological outcomes of traumatic brain injury (TBI) in mice: Inactivation of Caspase-3.
Brain Injuries, Traumatic
Detection of aII-spectrin and breakdown products in humans after severe traumatic brain injury.
Brain Injuries, Traumatic
Differential expression of apoptotic protease-activating factor-1 and caspase-3 genes and susceptibility to apoptosis during brain development and after traumatic brain injury.
Brain Injuries, Traumatic
Dual vulnerability of TDP-43 to calpain and caspase-3 proteolysis after neurotoxic conditions and traumatic brain injury.
Brain Injuries, Traumatic
Dynamic change of SGK expression and its role in neuron apoptosis after traumatic brain injury.
Brain Injuries, Traumatic
Endoplasmic reticulum stress-induced apoptosis in the penumbra aggravates secondary damage in rats with traumatic brain injury.
Brain Injuries, Traumatic
Erratum to: Degradation of ?II-Spectrin Protein by Calpain-2 and Caspase-3 Under Neurotoxic and Traumatic Brain Injury Conditions.
Brain Injuries, Traumatic
Evaluation of apoptosis in cerebrospinal fluid of patients with severe head injury.
Brain Injuries, Traumatic
Expression of Hsp70 and Caspase-3 in rabbits after severe traumatic brain injury.
Brain Injuries, Traumatic
Functional motor recovery from brain ischemic insult by carbon nanotube-mediated siRNA silencing.
Brain Injuries, Traumatic
Immunoblot analyses of the relative contributions of cysteine and aspartic proteases to neurofilament breakdown products following experimental brain injury in rats.
Brain Injuries, Traumatic
Increases in Bcl-2 and cleavage of caspase-1 and caspase-3 in human brain after head injury.
Brain Injuries, Traumatic
Inhibition of activated NR2B gene- and caspase-3 protein-expression by glutathione following traumatic brain injury in a rat model.
Brain Injuries, Traumatic
Inhibition of calpain and caspase-3 prevented apoptosis and preserved electrophysiological properties of voltage-gated and ligand-gated ion channels in rat primary cortical neurons exposed to glutamate.
Brain Injuries, Traumatic
Long-term accumulation of amyloid-beta, beta-secretase, presenilin-1, and caspase-3 in damaged axons following brain trauma.
Brain Injuries, Traumatic
Minocycline reduces traumatic brain injury-mediated caspase-1 activation, tissue damage, and neurological dysfunction.
Brain Injuries, Traumatic
Neat1 decreases neuronal apoptosis after oxygen and glucose deprivation.
Brain Injuries, Traumatic
Nestin overexpression precedes caspase-3 upregulation in rats exposed to controlled cortical impact traumatic brain injury.
Brain Injuries, Traumatic
p44/42 MAP kinase and c-Jun N-terminal kinase contribute to the up-regulation of caspase-3 in manganese-induced apoptosis in PC12 cells.
Brain Injuries, Traumatic
Regional calpain and caspase-3 proteolysis of alpha-spectrin after traumatic brain injury.
Brain Injuries, Traumatic
Role of Caspase 3 in neuronal apoptosis after acute brain injury.
Brain Injuries, Traumatic
Serum caspase-3 levels and mortality are associated in patients with severe traumatic brain injury.
Brain Injuries, Traumatic
Serum caspase-3 levels during the first week of traumatic brain injury.
Brain Injuries, Traumatic
Temporal and spatial profile of caspase 8 expression and proteolysis after experimental traumatic brain injury.
Brain Injuries, Traumatic
Temporal characterisation of pro- and anti-apoptotic mechanisms following diffuse traumatic brain injury in rats.
Brain Injuries, Traumatic
Temporal profile and cell subtype distribution of activated caspase-3 following experimental traumatic brain injury.
Brain Injuries, Traumatic
The neuroprotective effect of acute moderate alcohol consumption on caspase-3 mediated neuroapoptosis in traumatic brain injury: the role of lysosomal cathepsin L and nitric oxide.
Brain Injuries, Traumatic
[The study on the expression of caspase-3 in experimental brain contusion in rats]
Brain Ischemia
12 hours after cerebral ischemia is the optimal time for bone marrow mesenchymal stem cell transplantation.
Brain Ischemia
20(R)-Ginsenoside Rg3 protects SH-SY5Y cells against apoptosis induced by oxygen and glucose deprivation/reperfusion.
Brain Ischemia
Accumulation of calpain and caspase-3 proteolytic fragments of brain-derived alphaII-spectrin in cerebral spinal fluid after middle cerebral artery occlusion in rats.
Brain Ischemia
Activation and cleavage of caspase-3 in apoptosis induced by experimental cerebral ischemia.
Brain Ischemia
Activation of calpain, cathepsin-b and caspase-3 during transient focal cerebral ischemia in rat model.
Brain Ischemia
AKT/GSK3?-Dependent Autophagy Contributes to the Neuroprotection of Limb Remote Ischemic Postconditioning in the Transient Cerebral Ischemic Rat Model.
Brain Ischemia
ALDH 2 conferred neuroprotection on cerebral ischemic injury by alleviating mitochondria-related apoptosis through JNK/caspase-3 signing pathway.
Brain Ischemia
An-Gong-Niu-Huang Wan protects against cerebral ischemia induced apoptosis in rats: Up-regulation of Bcl-2 and down-regulation of Bax and caspase-3.
Brain Ischemia
Antrodia camphorata Potentiates Neuroprotection against Cerebral Ischemia in Rats via Downregulation of iNOS/HO-1/Bax and Activated Caspase-3 and Inhibition of Hydroxyl Radical Formation.
Brain Ischemia
Apoptosis inhibition in ischemic brain by intraperitoneal PTD-BIR3-RING (XIAP).
Brain Ischemia
Biochemical Characterization of a Caspase-3 Far-red Fluorescent Probe for Non-invasive Optical Imaging of Neuronal Apoptosis.
Brain Ischemia
Caspase-3 and the regulation of hypoxic neuronal death by vascular endothelial growth factor.
Brain Ischemia
Caspase-3 contributes to ZO-1 and Cl-5 tight-junction disruption in rapid anoxic neurovascular unit damage.
Brain Ischemia
Cleaved caspase-3 expression after experimental stroke exhibits different phenotypes and is predominantly non-apoptotic.
Brain Ischemia
Cross-talk Between Calpain and Caspase-3 in Penumbra and Core During Focal Cerebral Ischemia-reperfusion.
Brain Ischemia
Dapsone prolong delayed excitotoxic neuronal cell death by interacting with proapoptotic/survival signaling proteins.
Brain Ischemia
Deletion of cellular prion protein results in reduced Akt activation, enhanced postischemic caspase-3 activation, and exacerbation of ischemic brain injury.
Brain Ischemia
Development and brain delivery of chitosan-PEG nanoparticles functionalized with the monoclonal antibody OX26.
Brain Ischemia
Development of cerebral infarction, apoptotic cell death and expression of X-chromosome-linked inhibitor of apoptosis protein following focal cerebral ischemia in rats.
Brain Ischemia
Different doses of dexmedetomidine reduce plasma cytokine production, brain oxidative injury, PARP and caspase expression levels but increase liver oxidative toxicity in cerebral ischemia-induced rats.
Brain Ischemia
Differential changes of bax, caspase-3 and p21 mRNA expression after transient focal brain ischemia in the rat.
Brain Ischemia
Dysregulation of Autophagy, Mitophagy, and Apoptosis Genes in the CA3 Region of the Hippocampus in the Ischemic Model of Alzheimer's Disease in the Rat.
Brain Ischemia
Dysregulation of Autophagy, Mitophagy, and Apoptotic Genes in the Medial Temporal Lobe Cortex in an Ischemic Model of Alzheimer's Disease.
Brain Ischemia
Effect of aloe polysaccharide on caspase-3 expression following cerebral ischemia and reperfusion injury in rats.
Brain Ischemia
Effect of Electroacupuncture on Neurological Deficit and Activity of Clock and Bmal1 in Cerebral Ischemic Rats.
Brain Ischemia
Effect of Sevoflurane postconditioning on gene expression in brain tissue of the middle cerebral artery occlusion rat model.
Brain Ischemia
Effects of apoptosis-related proteins caspase-3, Bax and Bcl-2 on cerebral ischemia rats.
Brain Ischemia
Effects of chiral 3-n-butylphthalide on apoptosis induced by transient focal cerebral ischemia in rats.
Brain Ischemia
Effects of hsp70.1 gene knockout on the mitochondrial apoptotic pathway after focal cerebral ischemia.
Brain Ischemia
Emodin from Polygonum multiflorum ameliorates oxidative toxicity in HT22 cells and deficits in photothrombotic ischemia.
Brain Ischemia
Endothelin-1-mediated cerebral ischemia in mice: early cellular events and the role of caspase-3.
Brain Ischemia
Epigallocatechin gallate alleviates neuronal cell damage against focal cerebral ischemia in rats.
Brain Ischemia
Evidence of HIF-1 functional binding activity to caspase-3 promoter after photothrombotic cerebral ischemia.
Brain Ischemia
Expression profiles of microRNAs after focal cerebral ischemia/reperfusion injury in rats.
Brain Ischemia
Ginsenoside Rb1 regulates the expressions of brain-derived neurotrophic factor and caspase-3 and induces neurogenesis in rats with experimental cerebral ischemia.
Brain Ischemia
HIF-1? Activation Attenuates IL-6 and TNF-? Pathways in Hippocampus of Rats Following Transient Global Ischemia.
Brain Ischemia
Hinokitiol, a natural tropolone derivative, offers neuroprotection from thromboembolic stroke in vivo.
Brain Ischemia
Immunohistochemical and biochemical assessment of caspase-3 activation and DNA fragmentation following transient focal ischemia in the rat.
Brain Ischemia
Increased Renal Dysfunction, Apoptosis, and Fibrogenesis Through Sympathetic Hyperactivity After Focal Cerebral Infarction.
Brain Ischemia
Induction of caspase-3-like protease may mediate delayed neuronal death in the hippocampus after transient cerebral ischemia.
Brain Ischemia
Inhibiting Jumoji domain containing protein 3 (JMJD3) prevent neuronal apoptosis from stroke.
Brain Ischemia
Inhibition of caspase-3 activation and apoptosis is involved in 3-nitropropionic acid-induced ischemic tolerance to transient focal cerebral ischemia in rats.
Brain Ischemia
Inhibition of nNOS reduces ischemic cell death through down-regulating calpain and caspase-3 after experimental stroke.
Brain Ischemia
Inhibition of poly (ADP-ribose) polymerase and caspase-3, but not caspase-1, prevents apoptosis and improves spatial memory of rats with twice-repeated cerebral ischemia.
Brain Ischemia
Long-Lasting Actions of Progesterone Protect the Neonatal Brain Following Hypoxia-Ischemia.
Brain Ischemia
Mesencephalic astrocyte-derived neurotrophic factor prevents neuron loss via inhibiting ischemia-induced apoptosis.
Brain Ischemia
Microarray analysis of hippocampal gene expression in global cerebral ischemia.
Brain Ischemia
Mild hypothermia mitigates post-ischemic neuronal death following focal cerebral ischemia in rat brain: immunohistochemical study of Fas, caspase-3 and TUNEL.
Brain Ischemia
Mild hypothermia reduces activated caspase-3 up to 1 week after a focal cerebral ischemia induced by endothelin-1 in rats.
Brain Ischemia
Morphological and immunohistochemical analysis of apoptosis in the cerebellum of rats subjected to focal cerebral ischemia with or without alcoholism model.
Brain Ischemia
Morphological and immunohistochemical analysis of proteins CASPASE 3 and XIAP in rats subjected to cerebral ischemia and chronic alcoholism.
Brain Ischemia
Multimodal Neuroprotection Induced by PACAP38 in Oxygen-Glucose Deprivation and Middle Cerebral Artery Occlusion Stroke Models.
Brain Ischemia
Nesfatin-1 Improve Spatial Memory Impairment Following Transient Global Cerebral Ischemia/Reperfusion via Inhibiting Microglial and Caspase-3 Activation.
Brain Ischemia
Neuregulin-1 regulates the expression of Akt, Bcl-2, and Bad signaling after focal cerebral ischemia in rats.
Brain Ischemia
Neuroprotection by the Traditional Chinese Medicine, Tao-Hong-Si-Wu-Tang, against Middle Cerebral Artery Occlusion-Induced Cerebral Ischemia in Rats.
Brain Ischemia
Neuroprotective Effects and Mechanisms of Zhenlong Xingnao Capsule in In Vivo and In Vitro Models of Hypoxia.
Brain Ischemia
Neuroprotective effects of genistein-3'-sodium sulfonate on focal cerebral ischemia in rats.
Brain Ischemia
Neuroprotective effects of PMC, a potent alpha-tocopherol derivative, in brain ischemia-reperfusion: reduced neutrophil activation and anti-oxidant actions.
Brain Ischemia
Neuroprotective Effects of Xanthohumol, a Prenylated Flavonoid from Hops (Humulus lupulus), in Ischemic Stroke of Rats.
Brain Ischemia
Neuroprotective mechanism of taurine due to up-regulating calpastatin and down-regulating calpain and caspase-3 during focal cerebral ischemia.
Brain Ischemia
Neuroprotective mechanisms of puerarin in middle cerebral artery occlusion-induced brain infarction in rats.
Brain Ischemia
Neuroprotective Properties of Picroside II in a Rat Model of Focal Cerebral Ischemia.
Brain Ischemia
Novel Link of Anti-apoptotic ATF3 with Pro-apoptotic CTMP in the Ischemic Brain.
Brain Ischemia
PDZ1 inhibitor peptide protects neurons against ischemia via inhibiting GluK2-PSD-95-module-mediated Fas signaling pathway.
Brain Ischemia
Peroxisome proliferator-activated receptor delta regulation of miR-15a in ischemia-induced cerebral vascular endothelial injury.
Brain Ischemia
Peroxynitrite and caspase-3 expression after ischemia/reperfusion in mouse cardiac arrest model.
Brain Ischemia
Post-ischemic administration of progesterone reduces caspase-3 activation and DNA fragmentation in the hippocampus following global cerebral ischemia.
Brain Ischemia
Post-treatment of Bax-inhibiting peptide reduces neuronal death and behavioral deficits following global cerebral ischemia.
Brain Ischemia
Pre- and posttreatment with edaravone protects CA1 hippocampus and enhances neurogenesis in the subgranular zone of dentate gyrus after transient global cerebral ischemia in rats.
Brain Ischemia
Pre-ischemic exercise reduces apoptosis in hippocampal CA3 cells after cerebral ischemia by modulation of the Bax/Bcl-2 proteins ratio and prevention of caspase-3 activation.
Brain Ischemia
Prenatal hypoxia-induced adaptation and neuroprotection that is inducible nitric oxide synthase-dependent.
Brain Ischemia
Protection of Hippocampal CA1 Neurons Against Ischemia/Reperfusion Injury by Exercise Preconditioning via Modulation of Bax/Bcl-2 Ratio and Prevention of Caspase-3 Activation.
Brain Ischemia
Protein kinase C delta cleavage initiates an aberrant signal transduction pathway after cardiac arrest and oxygen glucose deprivation.
Brain Ischemia
Quercetin Attenuates Cell Apoptosis in Focal Cerebral Ischemia Rat Brain Via Activation of BDNF-TrkB-PI3K/Akt Signaling Pathway.
Brain Ischemia
Reduction in programmed cell death and improvement in functional outcome of transient focal cerebral ischemia after administration of granulocyte-macrophage colony-stimulating factor in rats.
Brain Ischemia
Rehmapicroside ameliorates cerebral ischemia-reperfusion injury via attenuating peroxynitrite-mediated mitophagy activation.
Brain Ischemia
Role of caspase-3 activation in cerebral ischemia-induced neurodegeneration in adult and neonatal brain.
Brain Ischemia
Saikosaponin A improved depression-like behavior and inhibited hippocampal neuronal apoptosis after cerebral ischemia through p-CREB/BDNF pathway.
Brain Ischemia
Scutellarin protects oxygen/glucose-deprived astrocytes and reduces focal cerebral ischemic injury.
Brain Ischemia
Spatial resolution of phospholipid scramblase 1 (PLSCR1), caspase-3 activation and DNA-fragmentation in the human hippocampus after cerebral ischemia.
Brain Ischemia
Specific Alterations of the HtrA2/HAX-1 Ratio in the Penumbra Upon Focal Cerebral Ischemia in Mice.
Brain Ischemia
Stabilization of HIF-1? modulates VEGF and caspase-3 in hippocampus of rats following transient global ischemia induced by asphyxial cardiac arrest.
Brain Ischemia
Sublethal cerebral ischemia inhibits caspase-3 activation induced by subsequent prolonged ischemia in the C57Black/Crj6 strain mouse.
Brain Ischemia
Synergetic Effects of Caspase 3 and mu-Calpain in XIAP-Breakdown upon Focal Cerebral Ischemia.
Brain Ischemia
Syringaldehyde exerts neuroprotective effect on cerebral ischemia injury in rats through anti-oxidative and anti-apoptotic properties.
Brain Ischemia
Talampanel a non-competitive AMPA-antagonist attenuates caspase-3 dependent apoptosis in mouse brain after transient focal cerebral ischemia.
Brain Ischemia
Tetramethylpyrazine suppresses HIF-1alpha, TNF-alpha, and activated caspase-3 expression in middle cerebral artery occlusion-induced brain ischemia in rats.
Brain Ischemia
The effect of low-energy laser irradiation on apoptotic factors following experimentally induced transient cerebral ischemia.
Brain Ischemia
The effects of middle cerebral artery occlusion on central nervous system apoptotic events in normal and diabetic rats.
Brain Ischemia
The neuroprotective effects of K252a through inhibiting MLK3/MKK7/JNK3 signaling pathway on ischemic brain injury in rat hippocampal CA1 region.
Brain Ischemia
The neuroprotective effects of preconditioning exercise on brain damage and neurotrophic factors after focal brain ischemia in rats.
Brain Ischemia
The role of Rho/Rho-kinase pathway and the neuroprotective effects of fasudil in chronic cerebral ischemia.
Brain Ischemia
Time-course of c-Jun N-terminal kinase activation after cerebral ischemia and effect of D-JNKI1 on c-Jun and caspase-3 activation.
Brain Ischemia
Tlr2 Deficiency is Associated with Enhanced Elements of Neuronal Repair and Caspase 3 Activation Following Brain Ischemia.
Brain Ischemia
TNF-? Receptor Inhibitor Alleviates Metabolic and Inflammatory Changes in a Rat Model of Ischemic Stroke.
Brain Ischemia
Total saponins of Panax notoginseng modulate the expression of caspases and attenuate apoptosis in rats following focal cerebral ischemia-reperfusion.
Brain Ischemia
Usnic acid improves memory impairment after cerebral ischemia/reperfusion injuries by anti-neuroinflammatory, anti-oxidant, and anti-apoptotic properties.
Brain Ischemia
[Effect of active fraction of buyang huanwu decoction on caspase expression in rats after focal cerebral ischemic reperfusion]
Brain Ischemia
[Effects of Carthamus tinctorius injection on bcl-2, caspase-3 expression related to neurons apoptosis after local cerebral ischemia]
Brain Ischemia
[Effects of electroacupuncture on cerebral Bcl-2 and caspase-3 expression after cerebral ischemia reperfusion in rats]
Brain Ischemia
[Effects of Naomaitong combined with mobilization of bone marrow mesenchymal stem cells on neuron apoptosis and expressions of Fas, FasL and caspase-3 proteins in rats with cerebral ischemia.]
Brain Ischemia
[Effects of Panax notoginseng saponins on mRNA expressions of interleukin-1 beta, its correlative factors and cysteinyl-aspartate specific protease after cerebral ischemia-reperfusion in rats]
Brain Ischemia
[Effects of sodium aescinate on bcl-2 and caspase-3 expression and apoptosis after focal cerebral ischemia reperfusion injury in rats]
Brain Ischemia
[The effect of interleukin-10 on neurocyte apoptosis in cerebral ischemia in rats]
Brain Neoplasms
Immunohistochemical markers associated with brain metastases in patients with nonsmall cell lung carcinoma.
Brain Neoplasms
Molecular evidence of apoptotic death in malignant brain tumors including glioblastoma multiforme: upregulation of calpain and caspase-3.
Brain Neoplasms
Molecular predictors of human nervous system cancer responsiveness to enediyne chemotherapy.
Brain Neoplasms
Neuroprotective effect of Cucumis melo Var. flexuosus leaf extract on the brains of rats with streptozotocin-induced diabetes.
Breast Diseases
Clinicopathological significance of PTEN and Caspase-3 expressions in breast cancer.
Breast Neoplasms
2-MeOE2bisMATE induces caspase-dependent apoptosis in CAL51 breast cancer cells and overcomes resistance to TRAIL via cooperative activation of caspases.
Breast Neoplasms
2-Methoxyestradiol and multidrug resistance: can 2-methoxyestradiol chemosensitize resistant breast cancer cells?
Breast Neoplasms
3-O-(E)-p-Coumaroyl betulinic acid possess anticancer activity and inhibit Notch signaling pathway in breast cancer cells and mammosphere.
Breast Neoplasms
4-Hydroxybenzoic acid (4-HBA) enhances the sensitivity of human breast cancer cells to adriamycin as a specific HDAC6 inhibitor by promoting HIPK2/p53 pathway.
Breast Neoplasms
5-flourouracil loaded N,O-carboxymethyl chitosan nanoparticles as an anticancer nanomedicine for breast cancer.
Breast Neoplasms
?-hydroxyundec-9-enoic acid induces apoptosis by ROS mediated JNK and p38 phosphorylation in breast cancer cell lines.
Breast Neoplasms
?-hydroxyundec-9-enoic acid induction of breast cancer cells apoptosis through generation of mitochondrial ROS and phosphorylation of AMPK.
Breast Neoplasms
?-Mangostin Induces Apoptosis and Inhibits Metastasis of Breast Cancer Cells via Regulating RXR?-AKT Signaling Pathway.
Breast Neoplasms
A methylene chloride fraction of Saururus chinensis induces apoptosis through the activation of caspase-3 in prostate and breast cancer cells.
Breast Neoplasms
A more aggressive breast cancer spheroid model coupled to an electronic capillary sensor system for a high-content screening of cytotoxic agents in cancer therapy: 3-dimensional in vitro tumor spheroids as a screening model.
Breast Neoplasms
A novel, patient-specific mathematical pathology approach for assessment of surgical volume: Application to ductal carcinoma in situ of the breast.
Breast Neoplasms
A novel, patient-specific mathematical pathology approach for assessment of surgical volume: application to ductal carcinoma in situ of the breast.
Breast Neoplasms
A novel, patient-specific mathematical pathology approach for assessment of surgical volume: Application to ductal carcinoma in situ of the breast.
Breast Neoplasms
A polymorphism in JMJD2C alters the cleavage by caspase-3 and the prognosis of human breast cancer.
Breast Neoplasms
A short caspase-3 isoform inhibits chemotherapy-induced apoptosis by blocking apoptosome assembly.
Breast Neoplasms
A small molecule Smac-mimic compound induces apoptosis and sensitizes TRAIL- and etoposide-induced apoptosis in breast cancer cells.
Breast Neoplasms
A study of the potential anticancer activity of Mangifera zeylanica bark: Evaluation of cytotoxic and apoptotic effects of the hexane extract and bioassay-guided fractionation to identify phytochemical constituents.
Breast Neoplasms
Activated Caspase 3 Expression in Remnant Disease After Neoadjuvant Chemotherapy May Predict Outcomes of Breast Cancer Patients.
Breast Neoplasms
Activation of caspase-3 activity and apoptosis in MDA-MB-468 cells by N(omega)-hydroxy-L-arginine, an inhibitor of arginase, is not solely dependent on reduction in intracellular polyamines.
Breast Neoplasms
Activation of caspase-3 and c-Jun NH2-terminal kinase-1 signaling pathways in tamoxifen-induced apoptosis of human breast cancer cells.
Breast Neoplasms
Active caspase-3 is removed from cells by release of caspase-3-enriched vesicles.
Breast Neoplasms
Adenosine and deoxyadenosine induces apoptosis in oestrogen receptor-positive and -negative human breast cancer cells via the intrinsic pathway.
Breast Neoplasms
Adenovirus-mediated p53 and ING4 gene co?transfer elicits synergistic antitumor effects through enhancement of p53 acetylation in breast cancer.
Breast Neoplasms
Adenovirus-mediated transfer of caspase-3 with Fas ligand induces drastic apoptosis in U-373MG glioma cells.
Breast Neoplasms
Administration with hyperoside sensitizes breast cancer cells to paclitaxel by blocking the TLR4 signaling.
Breast Neoplasms
Alteration of caspase-3 (CPP32/Yama/apopain) in wild-type MCF-7, breast cancer cells.
Breast Neoplasms
Altered expression of anti-apoptotic proteins in non-involved tissue from cancer-containing breasts.
Breast Neoplasms
An immunohistochemical evaluation of the proteins Wnt1 and glycogen synthase kinase (GSK)-3? in invasive breast carcinomas.
Breast Neoplasms
An In Vivo Study for Targeted Delivery of Curcumin in Human Triple Negative Breast Carcinoma Cells Using Biocompatible PLGA Microspheres Conjugated with Folic Acid.
Breast Neoplasms
Analysis of microRNA expression in canine mammary cancer stem-like cells indicates epigenetic regulation of transforming growth factor-beta signaling.
Breast Neoplasms
Angelica sinensis polysaccharides promotes apoptosis in human breast cancer cells via CREB-regulated caspase-3 activation.
Breast Neoplasms
Anti-Cancer Activity of Solanum nigrum (AESN) through Suppression of Mitochondrial Function and Epithelial-Mesenchymal Transition (EMT) in Breast Cancer Cells.
Breast Neoplasms
Anti-proliferation of breast cancer cells with itraconazole: Hedgehog pathway inhibition induces apoptosis and autophagic cell death.
Breast Neoplasms
Anticancer Activity of Ipomoea purpurea Leaves Extracts in Monolayer and Three-Dimensional Cell Culture.
Breast Neoplasms
Anticancer Potential of Silibinin Loaded Polymeric Nanoparticles against Breast Cancer Cells: Insight into the Apoptotic Genes Targets.
Breast Neoplasms
Antioxidant Rich Morus alba leaf Extract Induces Apoptosis in Human Colon and Breast Cancer Cells by the Downregulation of Nitric Oxide Produced by Inducible Nitric Oxide Synthase.
Breast Neoplasms
Antiproliferative activity of derivatives of ouabain, digoxin and proscillaridin A in human MCF-7 and MDA-MB-231 breast cancer cells.
Breast Neoplasms
Antiproliferative and Proapoptotic Activities of Marine Sponge Hyrtios erectus Extract on Breast Carcinoma Cell Line (MCF-7).
Breast Neoplasms
Apollon gene silencing induces apoptosis in breast cancer cells through p53 stabilisation and caspase-3 activation.
Breast Neoplasms
Apoptosis Cell Death Effect of Scrophularia Variegata on Breast Cancer Cells via Mitochondrial Intrinsic Pathway.
Breast Neoplasms
Apoptosis Inducing Effect of Andrographolide on TD-47 Human Breast Cancer Cell Line.
Breast Neoplasms
Apoptosis induction by dohevanil, a DHA substitutive analog of capsaicin, in MCF-7 cells.
Breast Neoplasms
Apoptosis induction in human breast cancer cell lines by synergic effect of raloxifene and resveratrol through increasing proapoptotic genes.
Breast Neoplasms
Apoptosis resistance of MCF-7 breast carcinoma cells to ionizing radiation is independent of p53 and cell cycle control but caused by the lack of caspase-3 and a caffeine-inhibitable event.
Breast Neoplasms
Apoptosis-mediated inhibition of human breast cancer cell proliferation by lemon citrus extract.
Breast Neoplasms
Apoptotic effect of eugenol envolves G2/M phase abrogation accompanied by mitochondrial damage and clastogenic effect on cancer cell in vitro.
Breast Neoplasms
Apoptotic induction mediated p53 mechanism and Caspase-3 activity by novel promising cyanoacrylamide derivatives in breast carcinoma.
Breast Neoplasms
Apoptotic role of marine sponge symbiont Bacillus subtilis NMK17 through the activation of caspase-3 in human breast cancer cell line.
Breast Neoplasms
Arsenic trioxide induces the apoptosis of human breast cancer MCF-7 cells through activation of caspase-3 and inhibition of HERG channels.
Breast Neoplasms
Balsamin induces apoptosis in breast cancer cells via DNA fragmentation and cell cycle arrest.
Breast Neoplasms
Cacalol, a natural sesquiterpene, induces apoptosis in breast cancer cells by modulating Akt-SREBP-FAS signaling pathway.
Breast Neoplasms
Cadmium modulates H-ras expression and caspase-3 apoptotic cell death in breast cancer epithelial MCF-7 cells.
Breast Neoplasms
Capsaicin Inhibits Proliferation and Induces Apoptosis in Breast Cancer by Down-Regulating FBI-1-Mediated NF-?B Pathway.
Breast Neoplasms
Capsaicin may induce breast cancer cell death through apoptosis-inducing factor involving mitochondrial dysfunction.
Breast Neoplasms
Carnosic acid cooperates with tamoxifen to induce apoptosis associated with Caspase-3 activation in breast cancer cells in vitro and in vivo.
Breast Neoplasms
Caspase-3 and caspase-8 expression in breast cancer: caspase-3 is associated with survival.
Breast Neoplasms
Caspase-3 inhibits the growth of breast cancer cells independent of protease activity.
Breast Neoplasms
Caspase-3 is essential for procaspase-9 processing and cisplatin-induced apoptosis of MCF-7 breast cancer cells.
Breast Neoplasms
Caspase-3 is necessary and sufficient for cleavage of protein synthesis eukaryotic initiation factor 4G during apoptosis.
Breast Neoplasms
Caspase-3 is required for alpha-fodrin cleavage but dispensable for cleavage of other death substrates in apoptosis.
Breast Neoplasms
Caspase-3 is required for DNA fragmentation and morphological changes associated with apoptosis.
Breast Neoplasms
Caspase-3 mediated programmed cell death by a gold-stabilised peptide carbene.
Breast Neoplasms
Caspase-3 over-expression is associated with poor overall survival and clinicopathological parameters in breast cancer: a meta-analysis of 3091 cases.
Breast Neoplasms
Caspase-3 status is a determinant of the differential responses to genistein between MDA-MB-231 and MCF-7 breast cancer cells.
Breast Neoplasms
Caspase-dependent and -independent events in apoptosis induced by hydrogen peroxide.
Breast Neoplasms
Caspase-dependent mitochondrial apoptotic pathway is involved in astilbin-mediated cytotoxicity in breast carcinoma cells.
Breast Neoplasms
Celastrol, a triterpene, enhances TRAIL-induced apoptosis through the down-regulation of cell survival proteins and up-regulation of death receptors.
Breast Neoplasms
Cell cycle arrest and apoptosis responses of human breast epithelial cells to the synthetic organosulfur compound p-methoxyphenyl p-toluenesulfonate.
Breast Neoplasms
Cell death induced by taxanes in breast cancer cells: cytochrome C is released in resistant but not in sensitive cells.
Breast Neoplasms
Cell death induction by Ranunculus ternatus extract is independent of mitochondria and dependent on Caspase-7.
Breast Neoplasms
Cell-specific induction of apoptosis by microinjection of cytochrome c. Bcl-xL has activity independent of cytochrome c release.
Breast Neoplasms
Cellular localization of the activated EGFR determines its effect on cell growth in MDA-MB-468 cells.
Breast Neoplasms
Chemical Composition of Aqueous Ethanol Extract of Luffa cylindrica Leaves and Its Effect on Representation of Caspase-8, Caspase-3, and the Proliferation Marker Ki67 in Intrinsic Molecular Subtypes of Breast Cancer in Vitro.
Breast Neoplasms
Chemopreventive Activity of Ferulago angulate against Breast Tumor in Rats and the Apoptotic Effect of Polycerasoidin in MCF7 Cells: A Bioassay-Guided Approach.
Breast Neoplasms
Chemotherapy resistance of mouse WAP-SVT/t breast cancer cells is mediated by osteopontin, inhibiting apoptosis downstream of caspase-3.
Breast Neoplasms
Chemotherapy with hybrid liposomes for human breast tumors along with apoptosis in vivo.
Breast Neoplasms
Chlorogenic acid induces 4T1 breast cancer tumor's apoptosis via p53, Bax, Bcl-2, and caspase-3 signaling pathways in BALB/c mice.
Breast Neoplasms
Cisplatin Loaded Multiwalled Carbon Nanotubes Induce Resistance in Triple Negative Breast Cancer Cells.
Breast Neoplasms
Cleavage of DFF-45/ICAD by multiple caspases is essential for its function during apoptosis.
Breast Neoplasms
Clinicopathological significance of PTEN and Caspase-3 expressions in breast cancer.
Breast Neoplasms
Combined Effect of Vaccinium nilgiriensis Bark Extract and 680 nm Laser Irradiation in Inducing Breast Cancer Cell Death.
Breast Neoplasms
Combined photodynamic therapy with chloroaluminum phthalocyanine and doxorubicin nanoemulsions in breast cancer model.
Breast Neoplasms
Comparative proteomic profiling of triple-negative breast cancer reveals that up-regulation of RhoGDI-2 is associated to the inhibition of caspase 3 and caspase 9.
Breast Neoplasms
Compound Opening Arrow Mixture exerts anti-tumor effects in a mouse model of breast cancer.
Breast Neoplasms
Concomitance of downregulated active caspase-3 and upregulated X-chromosome linked inhibitor of apoptosis protein as a sensitive diagnostic approach for breast cancer.
Breast Neoplasms
Contribution of reactive oxygen species and caspase-3 to apoptosis and attenuated ICAM-1 expression by paclitaxel-treated MDA-MB-435 breast carcinoma cells.
Breast Neoplasms
Correlation of Smac/DIABLO protein expression with the clinico-pathological features of breast cancer patients.
Breast Neoplasms
Curcumin inhibits proliferation and promotes apoptosis of breast cancer cells.
Breast Neoplasms
Cytotoxicity and induction of apoptosis of human breast cancer cells by novel platinum(II) complexes.
Breast Neoplasms
Cytotoxicity Of Chalcone Of Eugenia? aquea Burm F. Leaves Against T47D Breast Cancer Cell Lines And Its Prediction As An Estrogen Receptor Antagonist Based On Pharmacophore-Molecular Dynamics Simulation.
Breast Neoplasms
Degradation of HER2/neu by apigenin induces apoptosis through cytochrome c release and caspase-3 activation in HER2/neu-overexpressing breast cancer cells.
Breast Neoplasms
Design, synthesis and evaluation of marinopyrrole derivatives as selective inhibitors of Mcl-1 binding to pro-apoptotic Bim and dual Mcl-1/Bcl-xL inhibitors.
Breast Neoplasms
Design, synthesis, and biological activity of a potent Smac mimetic that sensitizes cancer cells to apoptosis by antagonizing IAPs.
Breast Neoplasms
Differential activity of caspase-3 regulates susceptibility of lung and breast tumor cell lines to Paclitaxel.
Breast Neoplasms
Distinct lymphocyte antigens 6 (Ly6) family members Ly6D, Ly6E, Ly6K and Ly6H drive tumorigenesis and clinical outcome.
Breast Neoplasms
DMSO exhibits similar cytotoxicity effects to thalidomide in mouse breast cancer cells.
Breast Neoplasms
DNA repair and apoptosis: Roles in radiotherapy-related acute reactions in breast cancer patients.
Breast Neoplasms
Docosahexaenoic acid intake decreases proliferation, increases apoptosis and decreases the invasive potential of the human breast carcinoma cell line MDA-MB-231.
Breast Neoplasms
Down-regulation of caspase 3 in breast cancer: a possible mechanism for chemoresistance.
Breast Neoplasms
Downregulation of Apaf-1 and caspase-3 by RNA interference in human glioma cells: consequences for erucylphosphocholine-induced apoptosis.
Breast Neoplasms
Drug-resistant breast carcinoma (MCF-7) cells are paradoxically sensitive to apoptosis.
Breast Neoplasms
Effect of Botulinum Toxin A on Proliferation and Apoptosis in the T47D Breast Cancer Cell Line.
Breast Neoplasms
Effect of miR-155 knockdown on the reversal of doxorubicin resistance in human lung cancer A549/dox cells.
Breast Neoplasms
Effect of weimaining on apoptosis and Caspase-3 expression in a breast cancer mouse model.
Breast Neoplasms
Effects of neoadjuvant therapies on genetic regulation of targeted pathways in ER+ primary ductal breast carcinoma: A meta-analysis of microarray datasets.
Breast Neoplasms
Effects of Spiro-bisheterocycles on Proliferation and Apoptosis in Human Breast Cancer Cell Lines.
Breast Neoplasms
Elevated expression of erbB3 confers paclitaxel resistance in erbB2-overexpressing breast cancer cells via upregulation of Survivin.
Breast Neoplasms
Endoplasmic reticulum stress mediates radiation-induced autophagy by perk-eIF2alpha in caspase-3/7-deficient cells.
Breast Neoplasms
Enhancement of hypoxia-induced apoptosis of human breast cancer cells via STAT5b by momilactone B.
Breast Neoplasms
Epigallocatechin-3-gallate induces apoptosis in estrogen receptor-negative human breast carcinoma cells via modulation in protein expression of p53 and Bax and caspase-3 activation.
Breast Neoplasms
Exosomes from M1-Polarized Macrophages Enhance Paclitaxel Antitumor Activity by Activating Macrophages-Mediated Inflammation.
Breast Neoplasms
Expression of caspase-3 and -7 does not correlate with the extent of apoptosis in primary breast carcinomas.
Breast Neoplasms
Expression of HIF-1? ODD domain fused canine caspase 3 by EGFR promoter-driven adenovirus vector induces cytotoxicity in canine breast tumor cells under hypoxia.
Breast Neoplasms
Expression of tumor necrosis factor alpha converting enzyme in endocrine cancers.
Breast Neoplasms
Expression of vascular endothelial growth factor and caspase-3 in mucinous breast carcinoma and infiltrating ductal carcinoma-not otherwise specified, and the correlation with disease-free survival.
Breast Neoplasms
Fabrication of methotrexate-loaded gold nanoconjugates and its enhanced anticancer activity in breast cancer.
Breast Neoplasms
Fasting cycles retard growth of tumors and sensitize a range of cancer cell types to chemotherapy.
Breast Neoplasms
Fenretinide induces autophagic cell death in caspase-defective breast cancer cells.
Breast Neoplasms
Fish oil targets PTEN to regulate NFkappaB for downregulation of anti-apoptotic genes in breast tumor growth.
Breast Neoplasms
Folic acid receptor-targeted solid lipid nanoparticles to enhance cytotoxicity of letrozole through induction of caspase-3 dependent-apoptosis for breast cancer treatment.
Breast Neoplasms
Functional screening of genes suppressing TRAIL-induced apoptosis: distinct inhibitory activities of Bcl-XL and Bcl-2.
Breast Neoplasms
Fungal taxol extracted from Cladosporium oxysporum induces apoptosis in T47D human breast cancer cell line.
Breast Neoplasms
Galangin potentiates human breast cancer to apoptosis induced by TRAIL through activating AMPK.
Breast Neoplasms
GALNT6 Promotes Tumorigenicity and Metastasis of Breast Cancer Cell via ?-catenin/MUC1-C Signaling Pathway.
Breast Neoplasms
Ganoderma lucidum spore oil induces apoptosis of breast cancer cells in vitro and in vivo by activating caspase-3 and caspase-9.
Breast Neoplasms
Gene expression and pathologic response to neoadjuvant chemotherapy in breast cancer.
Breast Neoplasms
Glucose restriction decreases telomerase activity and enhances its inhibitor response on breast cancer cells: possible extra-telomerase role of BIBR 1532.
Breast Neoplasms
Gonadotropin-releasing hormone type II antagonist induces apoptosis in MCF-7 and triple-negative MDA-MB-231 human breast cancer cells in vitro and in vivo.
Breast Neoplasms
Green-Synthesized Silver Nanoparticles Induced Apoptotic Cell Death in MCF-7 Breast Cancer Cells by Generating Reactive Oxygen Species and Activating Caspase 3 and 9 Enzyme Activities.
Breast Neoplasms
Growth inhibition and apoptotic effect of alpha-eleostearic acid on human breast cancer cells.
Breast Neoplasms
HDAC inhibitor SNDX-275 enhances efficacy of trastuzumab in erbB2-overexpressing breast cancer cells and exhibits potential to overcome trastuzumab resistance.
Breast Neoplasms
High Efficiency Apoptosis Induction in Breast Cancer Cell Lines by MLN4924/2DG Co-Treatment.
Breast Neoplasms
Hyaluronan-mediated CD44 interaction with p300 and SIRT1 regulates beta-catenin signaling and NFkappaB-specific transcription activity leading to MDR1 and Bcl-xL gene expression and chemoresistance in breast tumor cells.
Breast Neoplasms
Hybrid promoters directed tBid gene expression to breast cancer cells by transcriptional targeting.
Breast Neoplasms
Hydro-alcoholic Extract of Achillea Wilhelmsii C. Koch Reduces the Expression of Cell Death-Associated Genes while Inducing DNA Damage in HeLa Cervical Cancer Cells.
Breast Neoplasms
Identification of a conserved anti-apoptotic protein that modulates the mitochondrial apoptosis pathway.
Breast Neoplasms
Immunohistochemical expression of caspase-3 as an adverse indicator of the clinical outcome in human breast cancer.
Breast Neoplasms
Immunohistochemical heterogeneity of breast carcinomas negative for estrogen receptors, progesterone receptors and Her2/neu (basal-like breast carcinomas).
Breast Neoplasms
In Vitro Assessment of Homeopathic Potencies of Hydrastis canadensis on Hormone-Dependent and Independent Breast Cancer.
Breast Neoplasms
In vitro cytotoxicity of Clinacanthus nutans fractions on breast cancer cells and molecular docking study of sulphur containing compounds against caspase-3.
Breast Neoplasms
In vitro selected RNA aptamer recognizing glutathione induces ROS mediated apoptosis in the human breast cancer cell line MCF 7.
Breast Neoplasms
In vitro studies of a prolactin antagonist, hPRL-G129R in human breast cancer cells.
Breast Neoplasms
Increased sensitivity of African American triple negative breast cancer cells to nitric oxide-induced mitochondria-mediated apoptosis.
Breast Neoplasms
Inducing apoptosis effect of caffeic acid 3,4-dihydroxy-phenethyl ester on the breast cancer cells.
Breast Neoplasms
Induction of Apoptosis and Autophagy by Ternary Copper Complex Towards Breast Cancer Cells.
Breast Neoplasms
Induction of Apoptosis and Growth Arrest in Human Breast Carcinoma Cells by a Snake ( Walterinnesia aegyptia ) Venom Combined With Silica Nanoparticles: Crosstalk Between Bcl2 and Caspase 3.
Breast Neoplasms
Induction of apoptosis in human cancer cells by TZT-1027, an antimicrotubule agent.
Breast Neoplasms
Induction of cell cycle arrest and apoptosis by betulinic acid-rich fraction from Dillenia suffruticosa root in MCF-7 cells involved p53/p21 and mitochondrial signalling pathway.
Breast Neoplasms
Induction of cell cycle arrest and apoptosis in caspase-3 deficient MCF-7 cells by Dillenia suffruticosa root extract via multiple signalling pathways.
Breast Neoplasms
Influence of caspase activity on micronuclei detection: a possible role for caspase-3 in micronucleation.
Breast Neoplasms
Influence of MiR-451 on Drug Resistances of Paclitaxel-Resistant Breast Cancer Cell Line.
Breast Neoplasms
Influence of p53 and caspase 3 activity on cell death and senescence in response to methotrexate in the breast tumor cell.
Breast Neoplasms
Inhibition of Stat3 Signaling Pathway by Natural Product Pectolinarigenin Attenuates Breast Cancer Metastasis.
Breast Neoplasms
Inhibition of tumor growth by recombinant adenovirus containing human lactoferrin through inducing tumor cell apoptosis in mice bearing EMT6 breast cancer.
Breast Neoplasms
Inhibitory Effect of Lentivirus-Mediated Gag-Caspase-8 on the Growth of HER-2-Overexpressing Primary Human Breast Cancer Cells.
Breast Neoplasms
Inhibitory effects of combination of lycopene and genistein on 7,12- dimethyl benz(a)anthracene-induced breast cancer in rats.
Breast Neoplasms
Inositol 1,4,5-trisphosphate receptor type 1 is a substrate for caspase-3 and is cleaved during apoptosis in a caspase-3-dependent manner.
Breast Neoplasms
Investigation of the effects of distance from sources on apoptosis, oxidative stress and cytosolic calcium accumulation via TRPV1 channels induced by mobile phones and Wi-Fi in breast cancer cells.
Breast Neoplasms
Ionizing radiation-induced NF-kappaB activation requires PARP-1 function to confer radioresistance.
Breast Neoplasms
IRF-1 inhibits NF-?B activity, suppresses TRAF2 and cIAP1 and induces breast cancer cell specific growth inhibition.
Breast Neoplasms
Irofulven induces apoptosis in breast cancer cells regardless of caspase-3 status.
Breast Neoplasms
Kallistatin induces breast cancer cell apoptosis and autophagy by modulating Wnt signaling and microRNA synthesis.
Breast Neoplasms
KSP inhibitor SB743921 inhibits growth and induces apoptosis of breast cancer cells by regulating p53, Bcl-2, and DTL.
Breast Neoplasms
L-Carvone Induces p53, Caspase 3 Mediated Apoptosis and Inhibits the Migration of Breast Cancer Cell Lines.
Breast Neoplasms
Let-7a microRNA suppresses therapeutics-induced cancer cell death by targeting caspase-3.
Breast Neoplasms
Longitudinal bioluminescence imaging of the dynamics of Doxorubicin induced apoptosis.
Breast Neoplasms
Ly6E/K Signaling to TGF? Promotes Breast Cancer Progression, Immune Escape, and Drug Resistance.
Breast Neoplasms
Lysyl oxidase propeptide sensitizes pancreatic and breast cancer cells to doxorubicin-induced apoptosis.
Breast Neoplasms
Macrophage-mediated clearance of cells undergoing caspase-3-independent death.
Breast Neoplasms
Magnoflorine improves sensitivity to doxorubicin (DOX) of breast cancer cells via inducing apoptosis and autophagy through AKT/mTOR and p38 signaling pathways.
Breast Neoplasms
Magnolia dealbata seeds extract exert cytotoxic and chemopreventive effects on MDA-MB231 breast cancer cells.
Breast Neoplasms
Medicinal properties of Angelica archangelica root extract: Cytotoxicity in breast cancer cells and its protective effects against in vivo tumor development.
Breast Neoplasms
Melatonin regulates tumor aggressiveness under acidosis condition in breast cancer cell lines.
Breast Neoplasms
Metformin and melatonin improve histopathological outcome of NMU-induced mammary tumors in rats.
Breast Neoplasms
Methanolic extract of Pereskia bleo (Kunth) DC. (Cactaceae) induces apoptosis in breast carcinoma, T47-D cell line.
Breast Neoplasms
Methyl jasmonate decreases membrane fluidity and induces apoptosis through tumor necrosis factor receptor 1 in breast cancer cells.
Breast Neoplasms
Micro RNA 34a and Let-7a Expression in Human Breast Cancers is Associated with Apoptotic Expression Genes.
Breast Neoplasms
Microtubule-binding protein CLIP-170 is a mediator of paclitaxel sensitivity.
Breast Neoplasms
miR-205-3p promotes proliferation and reduces apoptosis of breast cancer MCF-7 cells and is associated with poor prognosis of breast cancer patients.
Breast Neoplasms
MiR-331-3p Links to Drug Resistance of Pancreatic Cancer Cells by Activating WNT/?-Catenin Signal via ST7L.
Breast Neoplasms
Mitomycin C induces apoptosis and caspase-8 and -9 processing through a caspase-3 and Fas-independent pathway.
Breast Neoplasms
Modification of Proliferation and Apoptosis in Breast Cancer Cells by Exposure of Antioxidant Nanoparticles Due to Modulation of the Cellular Redox State Induced by Doxorubicin Exposure.
Breast Neoplasms
Molecular profile of breast versus ovarian cancer cells in response to treatment with the anticancer drugs cisplatin, carboplatin, doxorubicin, etoposide and taxol.
Breast Neoplasms
mRNA expression of the putative antimetastatic gene BRMS1 and of apoptosis-related genes in breast cancer.
Breast Neoplasms
Multifunctional Thio-Stabilized Gold Nanoparticles for Near-Infrared Fluorescence Detection and Imaging of Activated Caspase-3.
Breast Neoplasms
Myricetin Apoptotic Effects on T47D Breast Cancer Cells is a P53-Independent Approach.
Breast Neoplasms
Myricetin Exerts its Apoptotic Effects on MCF-7 Breast Cancer Cells through Evoking the BRCA1-GADD45 Pathway.
Breast Neoplasms
N-Dihydrogalactochitosan Potentiates the Radiosensitivity of Liver Metastatic Tumor Cells Originated from Murine Breast Tumors.
Breast Neoplasms
Naringenin has a chemoprotective effect in MDA-MB-231 breast cancer cells via inhibition of caspase-3 and -9 activities.
Breast Neoplasms
Natural human gene correction by small extracellular genomic DNA fragments.
Breast Neoplasms
Neuraminidase 1 regulates proliferation, apoptosis and the expression of Cadherins in mammary carcinoma cells.
Breast Neoplasms
Nobiletin inhibits breast cancer via p38 mitogen-activated protein kinase, nuclear transcription factor-?B, and nuclear factor erythroid 2-related factor 2 pathways in MCF-7 cells.
Breast Neoplasms
Nodal and activin receptor-like kinase 7 induce apoptosis in human breast cancer cell lines: Role of caspase 3.
Breast Neoplasms
ON-III inhibits erbB-2 tyrosine kinase receptor signal pathway and triggers apoptosis through induction of Bim in breast cancer cells.
Breast Neoplasms
Overexpression of caspase-3 restores sensitivity for drug-induced apoptosis in breast cancer cell lines with acquired drug resistance.
Breast Neoplasms
Overexpression of caspase-3s splice variant in locally advanced breast carcinoma is associated with poor response to neoadjuvant chemotherapy.
Breast Neoplasms
Oxymatrine Promotes S-Phase Arrest and Inhibits Cell Proliferation of Human Breast Cancer Cells in Vitro through Mitochondria-Mediated Apoptosis.
Breast Neoplasms
PA-MSHA inhibits proliferation and induces apoptosis through the up-regulation and activation of caspases in the human breast cancer cell lines.
Breast Neoplasms
PEGylated chitosan nanoparticles potentiate repurposing of ormeloxifene in breast cancer therapy.
Breast Neoplasms
Phenotypic characterization of BRCA1 and BRCA2 tumors based in a tissue microarray study with 37 immunohistochemical markers.
Breast Neoplasms
Photodynamic therapy-induced death of MCF-7 human breast cancer cells: a role for caspase-3 in the late steps of apoptosis but not for the critical lethal event.
Breast Neoplasms
PND-1186 FAK inhibitor selectively promotes tumor cell apoptosis in three-dimensional environments.
Breast Neoplasms
Propofol induces apoptosis of breast cancer cells by downregulation of miR-24 signal pathway.
Breast Neoplasms
Protection by Bcl-2 against apoptotic but not autophagic cell death after photodynamic therapy.
Breast Neoplasms
Protein kinase C? and caspase-3 modulate TRAIL-induced apoptosis in breast tumor cells.
Breast Neoplasms
Putative tumor suppressor cytoglobin promotes aryl hydrocarbon receptor ligand-mediated triple negative breast cancer cell death.
Breast Neoplasms
Quercetin inhibits proliferation and invasion acts by up-regulating miR-146a in human breast cancer cells.
Breast Neoplasms
Randomized window of opportunity trial evaluating high-dose vitamin D in breast cancer patients.
Breast Neoplasms
Rapid and selective apoptosis in human leukemic cells induced by Aplidine through a Fas/CD95- and mitochondrial-mediated mechanism.
Breast Neoplasms
Ras-association domain family 1C protein promotes breast cancer cell migration and attenuates apoptosis.
Breast Neoplasms
Recombinant GnRH-p53 protein sensitizes breast cancer cells to 5-fluorouracil-induced apoptosis in vitro and in vivo.
Breast Neoplasms
Reconstitution of caspase 3 sensitizes MCF-7 breast cancer cells to doxorubicin- and etoposide-induced apoptosis.
Breast Neoplasms
Reconstitution of caspase-3 confers low glucose-enhanced tumor necrosis factor-related apoptosis-inducing ligand cytotoxicity and Akt cleavage.
Breast Neoplasms
Reconstitution of caspase-3 sensitizes MCF-7 breast cancer cells to radiation therapy.
Breast Neoplasms
Reconstitution of human MCF-7 breast cancer cells with caspase-3 does not sensitize them to action of CDK inhibitors.
Breast Neoplasms
Regulatory role of autophagy in globular adiponectin-induced apoptosis in cancer cells.
Breast Neoplasms
Resveratrol enhances the efficacy of sorafenib mediated apoptosis in human breast cancer MCF7 cells through ROS, cell cycle inhibition, caspase 3 and PARP cleavage.
Breast Neoplasms
Resveratrol-induced apoptosis in human breast cancer cells is mediated primarily through the caspase-3-dependent pathway.
Breast Neoplasms
Role of non-canonical Beclin 1-independent autophagy in cell death induced by resveratrol in human breast cancer cells.
Breast Neoplasms
Roscovitine-activated HIP2 kinase induces phosphorylation of wt p53 at Ser-46 in human MCF-7 breast cancer cells.
Breast Neoplasms
Ruthenium(II) p-cymene complex bearing 2,2'-dipyridylamine targets caspase 3 deficient MCF-7 breast cancer cells without disruption of antitumor immune response.
Breast Neoplasms
Salicylate suppresses the oncogenic hyaluronan network in metastatic breast cancer cells.
Breast Neoplasms
Scandenolone from Cudrania tricuspidata fruit extract suppresses the viability of breast cancer cells (MCF-7) in vitro and in vivo.
Breast Neoplasms
Self-assembled small messenger RNA nanospheres for efficient therapeutic apoptin expression and synergistic Gene-Chemotherapy of breast cancer.
Breast Neoplasms
Semaphorin 3B inhibits the phosphatidylinositol 3-kinase/Akt pathway through neuropilin-1 in lung and breast cancer cells.
Breast Neoplasms
Sensitivity to differential NRF1 gene signatures contributes to breast cancer disparities.
Breast Neoplasms
Smac/DIABLO enhances the therapeutic potential of chemotherapeutic drugs and irradiation, and sensitizes TRAIL-resistant breast cancer cells.
Breast Neoplasms
Somatostatin receptor targeted liposomes with Diacerein inhibit IL-6 for breast cancer therapy.
Breast Neoplasms
Steroidal hormones and proliferation, differentiation and apoptosis in breast cells.
Breast Neoplasms
Stimulatory Effect of Indolic Hormone on As2O3 Cytotoxicity in Breast Cancer Cells: NF-?B-dependent Mechanism of Action of Melatonin.
Breast Neoplasms
Sulforaphane induces cell type-specific apoptosis in human breast cancer cell lines.
Breast Neoplasms
Sulforaphane sensitizes human breast cancer cells to paclitaxel-induced apoptosis by downregulating the NF-?B signaling pathway.
Breast Neoplasms
Super Magnetic Niosomal Nanocarrier as a New Approach for Treatment of Breast Cancer: A Case Study on SK-BR-3 and MDA-MB-231 Cell Lines.
Breast Neoplasms
Suppressing glucose metabolism with epigallocatechin-3-gallate (EGCG) reduces breast cancer cell growth in preclinical models.
Breast Neoplasms
Suppression of PTEN/AKT signaling decreases the expression of TUBB3 and TOP2A with subsequent inhibition of cell growth and induction of apoptosis in human breast cancer MCF-7 cells via ATP and caspase-3 signaling pathways.
Breast Neoplasms
Survivin and caspase-3 expression in breast cancer: correlation with prognostic parameters, proliferation, angiogenesis, and outcome.
Breast Neoplasms
Synergistic action of cisplatin and echistatin in MDA-MB-231 breast cancer cells.
Breast Neoplasms
Synergistic Activity of Paclitaxel, Sorafenib, and Radiation Therapy in advanced Renal Cell Carcinoma and Breast Cancer.
Breast Neoplasms
Synergistic interactions of chemotherapeutic drugs and tumor necrosis factor-related apoptosis-inducing ligand/Apo-2 ligand on apoptosis and on regression of breast carcinoma in vivo.
Breast Neoplasms
Synergy between RA and TLR3 promotes type I IFN-dependent apoptosis through upregulation of TRAIL pathway in breast cancer cells.
Breast Neoplasms
Synthesis of a novel fluorescent berberine derivative convenient for its subcellular localization study.
Breast Neoplasms
Synthesis, biological evaluation and molecular docking studies of novel 1,2,3-triazole-quinazolines as antiproliferative agents displaying ERK inhibitory activity.
Breast Neoplasms
Synthesis, characterization and in vitro study of biocompatible cinnamaldehyde functionalized magnetite nanoparticles (CPGF Nps) for hyperthermia and drug delivery applications in breast cancer.
Breast Neoplasms
Targeted chemotherapy for triple-negative breast cancers via LHRH receptor.
Breast Neoplasms
Targeted inhibition of Notch1 gene enhances the killing effects of paclitaxel on triple negative breast cancer cells.
Breast Neoplasms
Taurine induces the apoptosis of breast cancer cells by regulating apoptosis-related proteins of mitochondria.
Breast Neoplasms
Taxol-induced apoptosis in human SKOV3 ovarian and MCF7 breast carcinoma cells is caspase-3 and caspase-9 independent.
Breast Neoplasms
Telomerase as a Possible Candidate Targeting Therapy in Different Breast Cancer Cell Lines.
Breast Neoplasms
Tetramethylpyrazine regulates breast cancer cell viability, migration, invasion and apoptosis by affecting the activity of Akt and caspase-3.
Breast Neoplasms
The bisphosphonate ibandronate promotes apoptosis in MDA-MB-231 human breast cancer cells in bone metastases.
Breast Neoplasms
The cyclin-dependent kinase inhibitor roscovitine and the nucleoside analog sangivamycin induce apoptosis in caspase-3 deficient breast cancer cells independent of caspase mediated P-glycoprotein cleavage: implications for therapy of drug resistant breast cancers.
Breast Neoplasms
The death of human cancer cells following photodynamic therapy: apoptosis competence is necessary for Bcl-2 protection but not for induction of autophagy.
Breast Neoplasms
The effect of adenosine A1 receptor agonist and antagonist on p53 and caspase 3, 8, and 9 expression and apoptosis rate in MCF-7 breast cancer cell line.
Breast Neoplasms
The Fanconi anemia pathway sensitizes to DNA alkylating agents by inducing JNK-p53-dependent mitochondrial apoptosis in breast cancer cells.
Breast Neoplasms
The histone deacetylase inhibitor sodium butyrate induces breast cancer cell apoptosis through diverse cytotoxic actions including glutathione depletion and oxidative stress.
Breast Neoplasms
The in vitro immunogenic potential of caspase-3 proficient breast cancer cells with basal low immunogenicity is increased by hypofractionated irradiation.
Breast Neoplasms
The mechanisms on apoptosis by inhibiting VEGF expression in human breast cancer cells.
Breast Neoplasms
The microtubule targeting agents eribulin and paclitaxel activate similar signaling pathways and induce cell death predominantly in a caspase-independent manner.
Breast Neoplasms
The naringenin-induced proapoptotic effect in breast cancer cell lines holds out against a high bisphenol a background.
Breast Neoplasms
The sequential treatment with ionizing radiation followed by TRAIL/Apo-2L reduces tumor growth and induces apoptosis of breast tumor xenografts in nude mice.
Breast Neoplasms
The small variant of the apoptosis-associated X-chromosome RBM10 gene is co-expressed with caspase-3 in breast cancer.
Breast Neoplasms
The tumor suppressor DAL-1/4.1B and protein methylation cooperate in inducing apoptosis in MCF-7 breast cancer cells.
Breast Neoplasms
Therapeutic Effect of Camel Milk and Its Exosomes on MCF7 Cells In Vitro and In Vivo.
Breast Neoplasms
Tranilast inhibits cell proliferation and migration and promotes apoptosis in murine breast cancer.
Breast Neoplasms
Triclabendazole Induces Pyroptosis by Activating Caspase-3 to Cleave GSDME in Breast Cancer Cells.
Breast Neoplasms
Tumor apoptosis induced by epoxide-containing piperazines, a new class of anti-cancer agents.
Breast Neoplasms
Tumor necrosis factor-? sensitizes breast cancer cells to natural products with proteasome-inhibitory activity leading to apoptosis.
Breast Neoplasms
Tumor-suppressive effect of adenovirus-mediated inhibitor of growth 4 gene transfer in breast carcinoma cells in vitro and in vivo.
Breast Neoplasms
Typhonium flagelliforme extract induce apoptosis in breast cancer stem cells by suppressing survivin.
Breast Neoplasms
Up-regulation of gamma-synuclein contributes to cancer cell survival under endoplasmic reticulum stress.
Breast Neoplasms
Validation of activated caspase-3 antibody staining as a marker of apoptosis in breast cancer.
Breast Neoplasms
VEGI, a new member of the TNF family activates nuclear factor-kappa B and c-Jun N-terminal kinase and modulates cell growth.
Breast Neoplasms
VP1 of foot-and-mouth disease virus induces apoptosis via the Akt signaling pathway.
Breast Neoplasms
Withanolide C Inhibits Proliferation of Breast Cancer Cells via Oxidative Stress-Mediated Apoptosis and DNA Damage.
Breast Neoplasms
YM155 down-regulates survivin and XIAP, modulates autophagy and induces autophagy-dependent DNA damage in breast cancer cells.
Breast Neoplasms
[Hirsutine induces apoptosis of human breast cancer MDA-MB-231 cells through mitochondrial pathway].
Breast Neoplasms
[Inhibitory effects of Aspisol on growth of transplanted breast cancer in C3H mice]
Breast Neoplasms
[Molecular mechanism of apoptosis of breast cancer SKBR-3 cells induced by cryptanshinone via G protein coupled estrogen receptor( GPER) mediated pathway].
Breast Neoplasms
[Synergistic Effect of 2-deoxy-D-glucose Combined with Hydroxycamptothecin on Apoptosis of Breast Cancer Cells].
Breast Neoplasms
[Tumor suppression of a constitutively active caspase-3 in the SKBr-3 breast carcinoma xenograft mice model]
Bronchitis
Design, synthesis and crystallographic analysis of nitrile-based broad-spectrum peptidomimetic inhibitors for coronavirus 3C-like proteases.
Bulbo-Spinal Atrophy, X-Linked
Caspase-3 cleaves the expanded androgen receptor protein of spinal and bulbar muscular atrophy in a polyglutamine repeat length-dependent manner.
Bulbo-Spinal Atrophy, X-Linked
Kennedy's disease. Phosphorylation of the polyglutamine-expanded form of androgen receptor regulates its cleavage by caspase-3 and enhances cell death.
Burkitt Lymphoma
Arsenic trioxide-induced apoptosis of human malignant lymphoma cell lines and its mechanisms.
Burkitt Lymphoma
Flavopiridol induces apoptosis and caspase-3 activation of a newly characterized Burkitt's lymphoma cell line containing mutant p53 genes.
Burkitt Lymphoma
Identification of apoptosis-associated proteins in a human Burkitt lymphoma cell line. Cleavage of heterogeneous nuclear ribonucleoprotein A1 by caspase 3.
Burkitt Lymphoma
Induction of apoptosis in E?-myc lymphoma cells in vitro and in vivo through calpain inhibition.
Burkitt Lymphoma
Inhibition of CPP32 blocks surface IgM-mediated apoptosis and D4-GDI cleavage in human BL60 Burkitt lymphoma cells.
Burkitt Lymphoma
Role of caspases and possible involvement of retinoblastoma protein during TGFbeta-mediated apoptosis of human B lymphocytes.
Burkitt Lymphoma
Zinc-mediated regulation of caspases activity: dose-dependent inhibition or activation of caspase-3 in the human Burkitt lymphoma B cells (Ramos).
Caliciviridae Infections
The feline calicivirus leader of the capsid protein causes survivin and XIAP downregulation and apoptosis.
Carcinogenesis
ABHD5 interacts with BECN1 to regulate autophagy and tumorigenesis of colon cancer independent of PNPLA2.
Carcinogenesis
Absence of Caspase-3 Protects Pancreatic {beta}-Cells from c-Myc-induced Apoptosis without Leading to Tumor Formation.
Carcinogenesis
Activation of apoptosis in hepatocellular carcinoma by the Chinese traditional medicine Hu Qisan.
Carcinogenesis
Adenovirus-mediated transfer of caspase-3 with Fas ligand induces drastic apoptosis in U-373MG glioma cells.
Carcinogenesis
Alteration in gene expression profile by full-length hepatitis B virus genome.
Carcinogenesis
Analysis of in vivo patterns of caspase 3 gene expression in primary hepatocellular carcinoma and its relationship to p21(WAF1) expression and hepatic apoptosis.
Carcinogenesis
Antitumor Activities of Ethyl Acetate Extracts from Selaginella doederleinii Hieron In Vitro and In Vivo and Its Possible Mechanism.
Carcinogenesis
Apigenin prevents deregulation in the expression pattern of cell-proliferative, apoptotic, inflammatory and angiogenic markers during 7,12-dimethylbenz[a]anthracene-induced hamster buccal pouch carcinogenesis.
Carcinogenesis
Apoptotic pathways and stemness in the colorectal epithelium and lamina propria mucosae during the human embryogenesis and carcinogenesis.
Carcinogenesis
Bis (Isothiocyanatomethyl) Benzene, A Plant Derived Anti-Neoplastic Compound: Purified from Moringa Oleifera Leaf Extract.
Carcinogenesis
Cadmium modulates H-ras expression and caspase-3 apoptotic cell death in breast cancer epithelial MCF-7 cells.
Carcinogenesis
CASP3 polymorphisms and risk of squamous cell carcinoma of the head and neck.
Carcinogenesis
Caspase-3 and caspase-8 expression in breast cancer: caspase-3 is associated with survival.
Carcinogenesis
Caspase-3 expression in tumorigenesis and prognosis of buccal mucosa squamous cell carcinoma.
Carcinogenesis
Caspase-3 expression is reduced, in the absence of cleavage, in terminally differentiated normal oral epithelium but is increased in oral squamous cell carcinomas and correlates with tumour stage.
Carcinogenesis
Chemopreventive activity of Azadirachta indica on two-stage skin carcinogenesis in murine model.
Carcinogenesis
Chemopreventive activity of Hydroethanolic Murraya koenigii leaves extract (HEMKLE) against chemically induced skin carcinogenesis in mice.
Carcinogenesis
Chemopreventive effect of selenium and Chinese medicinal herbs on N-nitrosobis(2-oxopropyl)amine-induced hepatocellular carcinoma in Syrian hamsters.
Carcinogenesis
Chemopreventive efficacy of hesperidin against chemically induced nephrotoxicity and renal carcinogenesis via amelioration of oxidative stress and modulation of multiple molecular pathways.
Carcinogenesis
Chemopreventive Role of Apigenin against the Synergistic Carcinogenesis of Human Papillomavirus and 4-(Methylnitrosamino)-1-(3-pyridyl)-1-butanone.
Carcinogenesis
Circ0120816 acts as an oncogene of esophageal squamous cell carcinoma by inhibiting miR-1305 and releasing TXNRD1.
Carcinogenesis
Clinicopathological significance of PTEN and Caspase-3 expressions in breast cancer.
Carcinogenesis
Clove (Syzygium aromaticum L.), a potential chemopreventive agent for lung cancer.
Carcinogenesis
Combination of S-allylcysteine and lycopene induces apoptosis by modulating Bcl-2, Bax, Bim and caspases during experimental gastric carcinogenesis.
Carcinogenesis
Comparison of the Biological Impact of UVA and UVB upon the Skin with Functional Proteomics and Immunohistochemistry.
Carcinogenesis
Constitutive transgene expression of Stem Cell Antigen-1 in the hair follicle alters the sensitivity to tumor formation and progression.
Carcinogenesis
Cyclooxygenase-2 inhibitor nimesulide blocks ultraviolet B-induced photocarcinogenesis in SKH-1 hairless mice.
Carcinogenesis
Distinct lymphocyte antigens 6 (Ly6) family members Ly6D, Ly6E, Ly6K and Ly6H drive tumorigenesis and clinical outcome.
Carcinogenesis
Down-regulation of miR-320 associated with cancer progression and cell apoptosis via targeting Mcl-1 in cervical cancer.
Carcinogenesis
Dysregulation of apoptosis by benzene metabolites and their relationships with carcinogenesis.
Carcinogenesis
Effects of treatment of rats with indole-3-carbinol on apoptosis in the mammary gland and mammary adenocarcinomas.
Carcinogenesis
Ellagic acid, a component of pomegranate fruit juice, suppresses androgen-dependent prostate carcinogenesis via induction of apoptosis.
Carcinogenesis
Essential roles of Caspase-3 in facilitating Myc-induced genetic instability and carcinogenesis.
Carcinogenesis
Estrogen promotes benzo[a]pyrene-induced lung carcinogenesis through oxidative stress damage and cytochrome c-mediated caspase-3 activation pathways in female mice.
Carcinogenesis
Ethanolic neem (Azadirachta indica) leaf extract induces apoptosis in the hamster buccal pouch carcinogenesis model by modulation of Bcl-2, Bim, caspase 8 and caspase 3.
Carcinogenesis
EWS/FLI1 oncogene activates caspase 3 transcription and triggers apoptosis in vivo.
Carcinogenesis
Ex vivo study of MAPK profiles correlated with parameters of apoptosis during cervical carcinogenesis.
Carcinogenesis
Expression levels of cleaved caspase-3 and caspase-3 in tumorigenesis and prognosis of oral tongue squamous cell carcinoma.
Carcinogenesis
Expression of Fas ligand and caspase-3 contributes to formation of immune escape in gastric cancer.
Carcinogenesis
Expression of Matrix Metalloproteinase-2, but not Caspase-3, Facilitates Distinction between Benign and Malignant Thyroid Follicular Neoplasms.
Carcinogenesis
Expression of survivin, p53, and caspase 3 in Barrett's esophagus carcinogenesis.
Carcinogenesis
Fas and its ligand, caspases, and bcl-2 expression in gonadotropin-releasing hormone agonist-treated uterine leiomyoma.
Carcinogenesis
Formylchromone exhibits salubrious effects against nitrosodiethylamine mediated early hepatocellular carcinogenesis in rats.
Carcinogenesis
Genetic Polymorphisms in the Apoptosis-Associated Gene CASP3 and the Risk of Lung Cancer in Chinese Population.
Carcinogenesis
Geraniol modulates cell proliferation, apoptosis, inflammation, and angiogenesis during 7,12-dimethylbenz[a]anthracene-induced hamster buccal pouch carcinogenesis.
Carcinogenesis
Growth, invasion, metastasis, differentiation, angiogenesis and apoptosis of gastric cancer regulated by expression of PTEN encoding products.
Carcinogenesis
Immunoexpression of cleaved caspase-3 shows lower apoptotic area indices in lip carcinomas than in intraoral cancer.
Carcinogenesis
Immunoexpression of DIABLO, AIF and cytochrome C in gastric adenocarcinoma assessed by tissue Microarray.
Carcinogenesis
Immunohistochemical analysis of apoptosis-related factors (Fas, Fas ligand, caspase-3 and single-stranded DNA) in ameloblastomas.
Carcinogenesis
Immunohistochemical study of NF-?B p65, c-IAP2 and caspase-3 expression in cervical cancer.
Carcinogenesis
Immunohistochemistry of programmed cell death in archival human pathology specimens.
Carcinogenesis
In vivo anticancer effects of Momordica charantia seed fat on hepatocellular carcinoma in a rat model.
Carcinogenesis
Knockdown of long noncoding RNA 00152 (LINC00152) inhibits human retinoblastoma progression.
Carcinogenesis
Metformin exhibited anticancer activity by lowering cellular cholesterol content in breast cancer cells.
Carcinogenesis
MiR-181c-5p Mitigates Tumorigenesis in Cervical Squamous Cell Carcinoma via Targeting Glycogen Synthase Kinase 3? Interaction Protein (GSKIP).
Carcinogenesis
miR-224 Is Significantly Upregulated and Targets Caspase-3 and Caspase-7 During Colorectal Carcinogenesis.
Carcinogenesis
MLAA-34 knockdown shows enhanced antitumor activity via JAK2/STAT3 signaling pathway in acute monocytic leukemia.
Carcinogenesis
Moderate DNA hypomethylation suppresses intestinal tumorigenesis by promoting caspase-3 expression and apoptosis.
Carcinogenesis
Modulating Pluripotency Network Genes with Omega-3 DHA is Followed by Caspase-3 Activation and Apoptosis in DNA Mismatch Repair-Deficient/KRAS-Mutant Colorectal Cancer Stem-Like Cells Modulating Pluripotency Network Genes with DHA
Carcinogenesis
Modulation of Angiogenesis, Proliferative Response and Apoptosis by ?-Sitosterol in Rat Model of Renal Carcinogenesis.
Carcinogenesis
Oleanolic Acid Suppressed DMBA-Induced Liver Carcinogenesis through Induction of Mitochondrial-Mediated Apoptosis and Autophagy.
Carcinogenesis
Oncogenic fusion protein EWS-FLI1 is a network hub that regulates alternative splicing.
Carcinogenesis
Protective effect of berberine on expression pattern of apoptotic, cell proliferative, inflammatory and angiogenic markers during 7,12-dimethylbenz(a)anthracene induced hamster buccal pouch carcinogenesis.
Carcinogenesis
Staphylococcus aureus Exploits the Host Apoptotic Pathway To Persist during Infection.
Carcinogenesis
Stem cell antigen-1 enhances tumorigenicity by disruption of growth differentiation factor-10 (GDF10)-dependent TGF-beta signaling.
Carcinogenesis
Survivin and Related Proteins in Canine Mammary Tumors: Immunohistochemical Expression.
Carcinogenesis
Tetramethylpyrazine (TMPZ) triggers S-phase arrest and mitochondria-dependent apoptosis in lung cancer cells.
Carcinogenesis
The Growing Complexity of Cancer Cell Response to DNA-Damaging Agents: Caspase 3 Mediates Cell Death or Survival?
Carcinogenesis
The Sca-1 cell surface marker enriches for a prostate-regenerating cell subpopulation that can initiate prostate tumorigenesis.
Carcinogenesis
The transmembrane protein LRIG1 triggers melanocytic tumor development following chemically induced skin carcinogenesis.
Carcinogenesis
Trichosanthin cooperates with Granzyme B to restrain tumor formation in tongue squamous cell carcinoma.
Carcinogenesis
Water extract of brewers' rice induces apoptosis in human colorectal cancer cells via activation of caspase-3 and caspase-8 and downregulates the Wnt/?-catenin downstream signaling pathway in brewers' rice-treated rats with azoxymethane-induced colon carcinogenesis.
Carcinogenesis
YBX1 regulates tumor growth via CDC25a pathway in human lung adenocarcinoma.
Carcinogenesis
[Down-regulation of Caspase-3 expression in precancerous lesions and its relation to gastric carcinogenesis]
Carcinogenesis
[Expression and significance of PTEN and caspase-3 in laryngeal squamous cell carcinoma]
Carcinogenesis
[Expression of apoptosis and proliferation related genes in carcinogenesis of lung squamous cell carcinoma in rats]
Carcinogenesis
[Expression of Caspase-3 and Bcl-2 in bladder transitional carcinoma and their significance]
Carcinogenesis
[Expression of survivin and caspase-3 in non-Hodgkin's lymphoma and their clinical significance]
Carcinogenesis
[Expression of Survivin mRNA and Caspase-3 mRNA and their correlation in tongue squamous cell carcinoma]
Carcinogenesis
[Expression of Survivin, Caspase-3 and p53 in surgical margin of laryngeal squamous cell carcinoma and their relationship]
Carcinogenesis
[Expression of survivin, caspase-3 in oral precancerous lesions and oral squamous-cell carcinoma.]
Carcinogenesis
[Expressions of survivin and caspase-3 in human non-small cell lung cancer and their relationship with cell apoptosis.]
Carcinogenesis
[PHARMACOLOGICAL CORRECTION OF APOPTOSIS LEVEL OF CORTICAL NEURONS IN AGED HER2/NEU TRANSGENIC MICE].
Carcinogenesis
[Roles of cyclooxygenase-2 and caspase-3 expression in pathogenesis of lung carcinoma: an experiment with rats]
Carcinogenesis
[The relationship between caspase-3 expression and cell proliferation in rat lung squamous cell carcinoma.]
Carcinoma
2-Methoxyestradiol-induced caspase-3 activation and apoptosis occurs through G(2)/M arrest dependent and independent pathways in gastric carcinoma cells.
Carcinoma
5,3'-Dihydroxy-6,7,4'-trimethoxyflavanone exerts its anticancer and antiangiogenesis effects through regulation of the Akt/mTOR signaling pathway in human lung cancer cells.
Carcinoma
?-Elemene promotes cisplatin-induced cell death in human bladder cancer and other carcinomas.
Carcinoma
A cyclooxygase-2 inhibitor NS-398-enhanced apoptosis of esophageal carcinoma cell EC9706 by adjusting expression of survivin and caspase-3.
Carcinoma
A cytotoxic protein (BF-CT1) purified from Bungarus fasciatus venom acts through apoptosis, modulation of PI3K/AKT, MAPKinase pathway and cell cycle regulation.
Carcinoma
A pilot study to assess the feasibility of evaluation of markers of response to chemotherapy at one day & 21 days after first cycle of chemotherapy in carcinoma of breast: a prospective non-randomized observational study.
Carcinoma
A pro-apoptotic 15-kDa protein from Bacopa monnieri activates caspase-3 and downregulates Bcl-2 gene expression in mouse mammary carcinoma cells.
Carcinoma
A review of molecular pathological markers in vulvar carcinoma: lack of application in clinical practice.
Carcinoma
Activation of actin-cleavable interleukin 1beta-converting enzyme (ICE) family protease CPP-32 during chemotherapeutic agent-induced apoptosis in ovarian carcinoma cells.
Carcinoma
Activation of caspase-3 in renal cell carcinoma cells by anthracyclines or 5-fluorouracil.
Carcinoma
Activation of caspase-3 noninvolved in the bystander effect of the herpes simplex virus thymidine kinase gene/ganciclovir (HSV-tk/GCV) system.
Carcinoma
Activation of intrinsic apoptotic signaling pathway in cancer cells by Cymbopogon citratus polysaccharide fractions.
Carcinoma
Active roles of caspase-3 in human gastric carcinoma cell death by apoptosis inducing nucleosides from CD57+HLA-DRbright natural suppressor cell line.
Carcinoma
Akt inhibitor enhances apoptotic effect of carboplatin on human epithelial ovarian carcinoma cell lines.
Carcinoma
Allicin induces apoptosis of the MGC-803 human gastric carcinoma cell line through the p38 mitogen-activated protein kinase/caspase-3 signaling pathway.
Carcinoma
Aloe-emodin, an anthraquinone, in vitro inhibits proliferation and induces apoptosis in human colon carcinoma cells.
Carcinoma
An experimental study on antitumoral effects of KI-21-3, a synthetic fragment of antimicrobial peptide LL-37, on oral squamous cell carcinoma.
Carcinoma
Analysis of expression of p63 and caspase-3 and their predictive value in patients with squamous cell carcinoma of maxillary sinus.
Carcinoma
Anti-apoptotic effects of curcumin on photosensitized human epidermal carcinoma A431 cells.
Carcinoma
Anti-apoptotic proteins Bcl-2/Bcl-XL inhibit Clostridium difficile toxin A-induced cell death in human epithelial cells.
Carcinoma
Anti-Cancer and Anti-Inflammatory Activities of Three New Chromone Derivatives from the Marine-Derived Penicillium citrinum.
Carcinoma
Anti-Cancer Effect of Quercetin in Xenograft Models with EBV-Associated Human Gastric Carcinoma.
Carcinoma
Anti-Fas antibody differentially regulates apoptosis in Fas ligand resistant carcinoma lines via the caspase 3 family of cell death proteases but independently of bcl2 expression.
Carcinoma
Anti-hepatoma cells function of luteolin through inducing apoptosis and cell cycle arrest.
Carcinoma
Anticancer activity of litchi fruit pericarp extract against human breast cancer in vitro and in vivo.
Carcinoma
Anticancer and Radiosensitization Efficacy of Nanocomposite Withania somnifera Extract in Mice Bearing Tumor Cells.
Carcinoma
Antineoplastic effects of clove buds (Syzygium aromaticum L.) in the model of breast carcinoma.
Carcinoma
Antiproliferative and Apoptotic Effects of Shemamruthaa, a Herbal Preparation, in 7,12-Dimethylbenz(a)Anthracene-Induced Breast Cancer Rats.
Carcinoma
Antitumor activity and induction of apoptosis by water-soluble derivatives of 7 beta-hydroxycholesterol in human colon carcinoma cell lines.
Carcinoma
Antitumor potential of SLPI promoter controlled recombinant caspase-3 expression in laryngeal carcinoma.
Carcinoma
Apoptosis and anti-apoptotic heat shock proteins in canine cutaneous infundibular keratinizing acanthomas and squamous cell carcinomas.
Carcinoma
Apoptosis in esophagus and pancreas carcinoma cells induced by circulating microparticles is related to phosphatidyl serine and microparticle-associated caspases.
Carcinoma
Apoptosis in gallbladder carcinomas and dysplasias, its relation to the expression of caspases 3, 6 and 8 and apoptosis regulating proteins bcl-2, mcl-1 and bax.
Carcinoma
Apoptosis of human carcinoma cells in the presence of potential anti-cancer drugs: III. Treatment of Colo-205 and SKBR3 cells with: cis -platin, Tamoxifen, Melphalan, Betulinic acid, L-PDMP, L-PPMP, and GD3 ganglioside.
Carcinoma
Apoptotic caspases inhibit abscopal responses to radiation and identify a new prognostic biomarker for breast cancer patients.
Carcinoma
Apoptotic signalling cascade in photosensitized human epidermal carcinoma A431 cells: involvement of singlet oxygen, c-Jun N-terminal kinase, caspase-3 and p21-activated kinase 2.
Carcinoma
Apotosis-related proteins in cervical intraepithelial neoplasia and squamous cell carcinoma of the cervix.
Carcinoma
Areca nut extract demonstrated apoptosis-inducing mechanism by increased caspase-3 activities on oral squamous cell carcinoma.
Carcinoma
Argpyrimidine-modified Heat shock protein 27 in human non-small cell lung cancer: a possible mechanism for evasion of apoptosis.
Carcinoma
Assessment of apoptosis by immunohistochemistry to active caspase-3, active caspase-7, or cleaved PARP in monolayer cells and spheroid and subcutaneous xenografts of human carcinoma.
Carcinoma
Assessment of M867, a selective caspase-3 inhibitor, in an orthotopic mouse model for non-small cell lung carcinoma.
Carcinoma
Association of Casp3 microRNA Target Site (1049216) SNP With the Risk and Progress of Cervical Squamous Cell Carcinoma.
Carcinoma
Association of CASP3 polymorphism with hematologic toxicity in patients with advanced non-small-cell lung carcinoma treated with platinum-based chemotherapy.
Carcinoma
Augmented adriamycin sensitivity in cells transduced with an antisense tumor necrosis factor gene is mediated by caspase-3 downstream from reactive oxygen species.
Carcinoma
Autocatalytic caspase-3 driven by human telomerase reverse transcriptase promoter suppresses human ovarian carcinoma growth in vitro and in mice.
Carcinoma
B7-H4 is Inversely Correlated With T-Cell Infiltration in Clear Cell but Not Serous or Endometrioid Ovarian Cancer.
Carcinoma
Baicalein blocked cervical carcinoma cell proliferation by targeting CCND1 via Wnt/?-catenin signaling pathway.
Carcinoma
Bcl-2 independence of flavopiridol-induced apoptosis. Mitochondrial depolarization in the absence of cytochrome c release.
Carcinoma
Bcl10 crucially nucleates the pro-apoptotic complexes comprising PDK1, PKC? and caspase-3 at the nuclear envelope of etoposide-treated human cervical carcinoma C4-I cells.
Carcinoma
Berberine regulates the microRNA-21-ITG?4-PDCD4 axis and inhibits colon cancer viability.
Carcinoma
Bioengineered arginase I increases caspase-3 expression of hepatocellular and pancreatic carcinoma cells despite induction of argininosuccinate synthetase-1.
Carcinoma
Bioengineering functional copolymers. XIV. Synthesis and interaction of poly(N-isopropylacrylamide-co-3,4-dihydro-2H-pyran-alt-maleic anhydride)s with SCLC cancer cells.
Carcinoma
Boschniakia Rossica Polysaccharide Triggers Laryngeal Carcinoma Cell Apoptosis by Regulating Expression of Bcl-2, Caspase-3, and P53.
Carcinoma
Bovine lactoferricin selectively induces apoptosis in human leukemia and carcinoma cell lines.
Carcinoma
c-Abl Is an Upstream Regulator of Acid Sphingomyelinase in Apoptosis Induced by Inhibition of Integrins ?v?3 and ?v?5.
Carcinoma
c-Abl-independent p73 stabilization during gemcitabine- or 4'-thio-{beta}-D-arabinofuranosylcytosine-induced apoptosis in wild-type and p53-null colorectal cancer cells.
Carcinoma
Capsaicin provokes apoptosis and restricts benzo(a)pyrene induced lung tumorigenesis in Swiss albino mice.
Carcinoma
Casein kinase 2 inhibition differentially modulates apoptotic effect of trichostatin A against epithelial ovarian carcinoma cell lines.
Carcinoma
CASP3 and LDOC-1 gene expression in a patient with carcinoma in the hairy part of the head skin and Alzheimer disease.
Carcinoma
CASP8 (rs3834129) and CASP3 (rs4647601) polymorphisms in oropharynx cancer risk, tumor cell differentiation, and prognosis in a cohort of the Brazilian population.
Carcinoma
CASP9 c.-1339A>G and CASP3 c.-1191A>G polymorphisms alter susceptibility and clinical aspects of head and neck squamous cell carcinoma.
Carcinoma
Caspase 3 as a Novel Marker to Distinguish Chromophobe Renal Cell Carcinoma from Oncocytoma.
Carcinoma
Caspase-3 activation downstream from reactive oxygen species in heat-induced apoptosis of pancreatic carcinoma cells carrying a mutant p53 gene.
Carcinoma
Caspase-3 activation is not responsible for vinblastine-induced Bcl-2 phosphorylation and G2/M arrest in human small cell lung carcinoma Ms-1 cells.
Carcinoma
Caspase-3 expression in metastatic lymph nodes of esophageal squamous cell carcinoma is prognostic of survival.
Carcinoma
Caspase-3 expression in normal oral epithelium, oral submucous fibrosis and oral squamous cell carcinoma.
Carcinoma
Caspase-3 expression in tumorigenesis and prognosis of buccal mucosa squamous cell carcinoma.
Carcinoma
Caspase-3 expression is reduced, in the absence of cleavage, in terminally differentiated normal oral epithelium but is increased in oral squamous cell carcinomas and correlates with tumour stage.
Carcinoma
Caspase-3/CPP32 immunoreactivity and its correlation with frequency of apoptotic bodies in human prostatic carcinomas and benign nodular hyperplasias.
Carcinoma
Caveolin-1 expression sensitizes fibroblastic and epithelial cells to apoptotic stimulation.
Carcinoma
Cellular apoptosis susceptibility gene expression in endometrial carcinoma: correlation with Bcl-2, Bax, and caspase-3 expression and outcome.
Carcinoma
Characterization and antitumor activity of the extracellular carbohydrate polymer from the cyanobacterium Synechocystis ?sigF mutant.
Carcinoma
Chemopreventive activity of Azadirachta indica on two-stage skin carcinogenesis in murine model.
Carcinoma
Chemopreventive and Therapeutic Efficacy of Cinnamomum zeylanicum L. Bark in Experimental Breast Carcinoma: Mechanistic In Vivo and In Vitro Analyses.
Carcinoma
Chios Mastic Gum Extracts as a Potent Antitumor Agent that Inhibits Growth and Induces Apoptosis of Oral Cancer Cells.
Carcinoma
Chromic-P32 phosphate treatment of implanted pancreatic carcinoma: mechanism involved.
Carcinoma
Cisplatin inhibits the expression of X-chromosome-linked inhibitor of apoptosis protein in an oral carcinoma cell line.
Carcinoma
Cisplatin resistance in an ovarian carcinoma is associated with a defect in programmed cell death control through XIAP regulation.
Carcinoma
Cleaved caspase-3 and nuclear factor-kappaB p65 are prognostic factors in metastatic serous ovarian carcinoma.
Carcinoma
Clinical and experimental study of oxaliplatin in treating human gastric carcinoma.
Carcinoma
Clinicopathological and prognostic significance of Ki-67, caspase-3 and p53 expression in gastric carcinomas.
Carcinoma
Co-expression of caspase-3 or caspase-8 with galanin in the human stomach section affected by carcinoma.
Carcinoma
Combination of Pitavastatin and melatonin shows partial antineoplastic effects in a rat breast carcinoma model.
Carcinoma
Combination of S-allylcysteine and lycopene induces apoptosis by modulating Bcl-2, Bax, Bim and caspases during experimental gastric carcinogenesis.
Carcinoma
Combinatorial chemopreventive effect of Azadirachta indica and Ocimum sanctum on oxidant-antioxidant status, cell proliferation, apoptosis and angiogenesis in a rat forestomach carcinogenesis model.
Carcinoma
Combined application of camptothecin and the guanylate cyclase activator YC-1: Impact on cell death and apoptosis-related proteins in ovarian carcinoma cell lines.
Carcinoma
Comparative evaluation of antiproliferative, antiangiogenic and apoptosis inducing potential of black tea polyphenols in the hamster buccal pouch carcinogenesis model.
Carcinoma
Concise synthesis and biological evaluation of 2-Aryl-3-Anilinobenzo[b]thiophene derivatives as potent apoptosis-inducing agents.
Carcinoma
Cordycepin induces apoptosis in human bladder cancer cells via activation of A3 adenosine receptors.
Carcinoma
Cyclosporine A enhances apoptosis in gingival keratinocytes of rats and in OECM1 cells via the mitochondrial pathway.
Carcinoma
Cytochrome c is involved in Fas-mediated apoptosis of prostatic carcinoma cell lines.
Carcinoma
Cytoplasmic and nuclear maspin expression in lung carcinomas: an immunohistochemical study using tissue microarrays.
Carcinoma
Cytotoxic 2-benzylidene-6-(nitrobenzylidene)cyclohexanones which display substantially greater toxicity for neoplasms than non-malignant cells.
Carcinoma
Cytotoxic and Apoptotic Effects of Ethyl Acetate Extract of Elephantopus mollis Kunth. in Human Liver Carcinoma HepG2 Cells Through Caspase-3 Activation.
Carcinoma
Cytotoxic Components Against Human Oral Squamous Cell Carcinoma Isolated from Andrographis paniculata.
Carcinoma
DAO-9 (2,5-di(4-aryloylaryloxymethyl)-1,3,4-oxadiazole) exhibits p53 induced apoptogenesis through caspase-3 mediated endonuclease activity in murine carcinoma.
Carcinoma
Detection of apoptosis and expression of apoptosis-associated proteins as early predictors of prognosis after irradiation therapy in stage IIIb uterine cervical cancer.
Carcinoma
Development of plasmin and plasma kallikrein selective inhibitors and their effect on M1 (melanoma) and HT29 cell lines.
Carcinoma
Differential expression of intracellular apoptotic signaling molecules in tumor and tumor-infiltrating lymphocytes during development of invasion and/or metastasis of gastric carcinoma.
Carcinoma
Differential expression of microRNA501-5p affects the aggressiveness of clear cell renal carcinoma.
Carcinoma
Differential targets and subcellular localization of antitumor alkyl-lysophospholipid in leukemic versus solid tumor cells.
Carcinoma
Dioscin-induced apoptosis of human LNCaP prostate carcinoma cells through activation of caspase-3 and modulation of Bcl-2 protein family.
Carcinoma
DNA fragmentation is not associated with apoptosis in zerumbone-induced HepG2 cells.
Carcinoma
Effect of berberine nanoemulsion Photodynamic therapy on cervical carcinoma cell line.
Carcinoma
Effect of Oversulfation on the Composition, Structure, and In Vitro Anti-Lung Cancer Activity of Fucoidans Extracted from Sargassum aquifolium.
Carcinoma
Effect of photodynamic therapy on expression of HRAS, NRAS and caspase 3 genes at mRNA levels, apoptosis of head and neck squamous cell carcinoma cell line.
Carcinoma
Effect of protein kinase C alpha, caspase-3, and survivin on apoptosis of oral cancer cells induced by staurosporine.
Carcinoma
Effects of physical activity and restricted energy intake on chemically induced mammary carcinogenesis.
Carcinoma
Enhanced apoptosis of squamous cell carcinoma cells by interleukin-2-activated cytotoxic lymphocytes combined with radiation and anticancer drugs.
Carcinoma
Epigallocatechin-3-gallate induces mitochondrial membrane depolarization and caspase-dependent apoptosis in pancreatic cancer cells.
Carcinoma
Erratum to: CASP3 and LDOC-1 gene expression in a patient with carcinoma in the hairy part of the head skin and Alzheimer disease.
Carcinoma
Ethanolic neem (Azadirachta indica) leaf extract induces apoptosis in the hamster buccal pouch carcinogenesis model by modulation of Bcl-2, Bim, caspase 8 and caspase 3.
Carcinoma
Eupalitin induces apoptosis in prostate carcinoma cells through ROS generation and increase of caspase-3 activity.
Carcinoma
Evaluation of caspase-3 and caspase-8 deregulation in tongue squamous cell carcinoma, based on immunohistochemistry and computerised image analysis.
Carcinoma
Evaluation of p53, Caspase-3, Bcl-2, and Ki-67 markers in oral squamous cell carcinoma and premalignant epithelium in a sample from Alava Province (Spain).
Carcinoma
Exogenous morphine inhibits human gastric cancer MGC- 803 cell growth by cell cycle arrest and apoptosis induction.
Carcinoma
Experimental gene therapy in mammary and urinary bladder cancer using electrogene transfer.
Carcinoma
Exploring new applications of tulip tree (Liriodendron tulipifera L.): leaf essential oil as apoptotic agent for human glioblastoma.
Carcinoma
Expression and Prognostic Significance of Livin, Caspase-3, and Ki-67 in the Progression of Human Ampullary Carcinoma.
Carcinoma
Expression and subcellular distribution of Bcl-2 and BAX proteins in serum-starved human keratinocytes and mouth carcinoma epidermoid cultures.
Carcinoma
Expression levels of cleaved caspase-3 and caspase-3 in tumorigenesis and prognosis of oral tongue squamous cell carcinoma.
Carcinoma
Expression of apoptosis-related proteins and its clinical implication in surgically resected gastric carcinoma.
Carcinoma
Expression of apoptotic and cell proliferation regulatory proteins in keratoacanthomas and squamous cell carcinomas of the skin.
Carcinoma
Expression of Bax and apoptosis-related proteins in human esophageal squamous cell carcinoma including dysplasia.
Carcinoma
Expression of caspases 3, 6 and 8 is increased in parallel with apoptosis and histological aggressiveness of the breast lesion.
Carcinoma
Expression of caspases-3, -6 and -8 and their relation to apoptosis in non-small cell lung carcinoma.
Carcinoma
Expression of ki-67 antigen and caspase-3 protein in benign lesions and esophageal carcinoma.
Carcinoma
Expression of multiple apoptosis-regulatory genes in human breast cancer cell lines and primary tumors.
Carcinoma
Expression of peripheral benzodiazepine receptor, PCNA, and caspase-3 in cells of skin melanoma and squamous cell carcinoma.
Carcinoma
Expression of procaspase 3 and activated caspase 3 and its relevance in hormone-responsive gallbladder carcinoma chemotherapy.
Carcinoma
Expression of PTEN and FHIT is involved in regulating the balance between apoptosis and proliferation in lung carcinomas.
Carcinoma
Expression of survivin and caspase 3 in oral squamous cell carcinoma and peritumoral tissue.
Carcinoma
Expression of the pro-apoptotic caspase 3/CPP32 in cutaneous basal and squamous cell carcinomas.
Carcinoma
Expression Profiling of Proliferation and Apoptotic Markers along the Adenoma-Carcinoma Sequence in Familial Adenomatous Polyposis Patients.
Carcinoma
FAS and FASL variations in outcomes of tobacco- and alcohol-related head and neck squamous cell carcinoma patients.
Carcinoma
Fas-mediated pathway and apoptosis in normal, hyperplastic, and neoplastic endometrium.
Carcinoma
Fenretinide induces autophagic cell death in caspase-defective breast cancer cells.
Carcinoma
Four-and-a-half LIM protein 1 promotes paclitaxel resistance in hepatic carcinoma cells through the regulation of caspase-3 activation.
Carcinoma
Fruit peel polyphenols demonstrate substantial anti-tumour effects in the model of breast cancer.
Carcinoma
Fumonisin B1 Inhibits Endoplasmic Reticulum Stress Associated-apoptosis After FoscanPDT Combined with C6-Pyridinium Ceramide or Fenretinide.
Carcinoma
Galangin suppresses human laryngeal carcinoma via modulation of caspase-3 and AKT signaling pathways.
Carcinoma
Garlic ((Allium sativum)) Fresh Juice Induces Apoptosis in Human Oral Squamous Cell Carcinoma: The Involvement of Caspase-3, Bax and Bcl-2.
Carcinoma
Ge-Jee-Bok-Ryung-Hwan induces apoptosis in human cervical carcinoma HeLa cells--an endoplasmic reticulum stress pathway--.
Carcinoma
Gene expression analysis identifies two groups of ovarian high-grade serous carcinomas with different prognosis.
Carcinoma
Genetic variant in CASP3 affects promoter activity and risk of esophageal squamous cell carcinoma.
Carcinoma
Genotoxic evaluation of the antimalarial drugs artemisinin and artesunate in human HepG2 cells and effects on CASP3 and SOD1 gene expressions.
Carcinoma
Glucocorticoid cotreatment induces apoptosis resistance toward cancer therapy in carcinomas.
Carcinoma
Green tea polyphenol targets the mitochondria in tumor cells inducing caspase 3-dependent apoptosis.
Carcinoma
Herpes simplex virus thymidine kinase/ganciclovir-induced cell death is enhanced by co-expression of caspase-3 in ovarian carcinoma cells.
Carcinoma
Histologic evaluation of Ki-67 and cleaved caspase-3 expression in feline mammary carcinoma.
Carcinoma
Histone deacetylase inhibitors require caspase activity to induce apoptosis in lung and prostate carcinoma cells.
Carcinoma
HLJ1 is a novel caspase-3 substrate and its expression enhances UV-induced apoptosis in non-small cell lung carcinoma.
Carcinoma
HOXC13 promotes proliferation of esophageal squamous cell carcinoma via repressing transcription of CASP3.
Carcinoma
Human cathelicidin antimicrobial peptide suppresses proliferation, migration and invasion of oral carcinoma HSC-3 cells via a novel mechanism involving caspase-3 mediated apoptosis.
Carcinoma
Hyperthermia Suppresses Post - In Vitro Proliferation and Tumor Growth in Murine Malignant Melanoma and Colon Carcinoma.
Carcinoma
Hypoxia-inducible factor (HIF-1) and its relationship to apoptosis and proliferation in lung cancer.
Carcinoma
Identifying cancer-related molecular targets of Nandina domestica Thunb. by network pharmacology-based analysis in combination with chemical profiling and molecular docking studies.
Carcinoma
Immunoexpression of cleaved caspase-3 shows lower apoptotic area indices in lip carcinomas than in intraoral cancer.
Carcinoma
Immunohistochemical evaluation of bcl-2, ER-alpha, caspase -3, -8, -9, PCNA and Ki-67 expressions in canine mammary carcinomas.
Carcinoma
Immunohistochemical study of pro-apoptotic factors Bax, Fas and CPP32 in urinary bladder cancer: prognostic implications.
Carcinoma
Implication of caspase-3 and granzyme B expression and activity in spleenocytes of ehrlich ascites carcinoma mice subjected to immunotherapy.
Carcinoma
Implication of mitochondria-derived reactive oxygen species, cytochrome C and caspase-3 in N-(4-hydroxyphenyl)retinamide-induced apoptosis in cervical carcinoma cells.
Carcinoma
Increased killing of SCCVII squamous cell carcinoma cells after the combination of Pc 4 photodynamic therapy and dasatinib is associated with enhanced caspase-3 activity and ceramide synthase 1 upregulation.
Carcinoma
Induction of apoptosis by Hypericin through activation of caspase-3 in human carcinoma cells.
Carcinoma
Induction of apoptosis by isothiocyanate sulforaphane in human cervical carcinoma HeLa and hepatocarcinoma HepG2 cells through activation of caspase-3.
Carcinoma
Induction of apoptosis in human lung carcinoma cells by the water extract of Panax notoginseng is associated with the activation of caspase-3 through downregulation of Akt.
Carcinoma
Induction of apoptosis in the SW620 colon carcinoma cell line by triterpene-enriched extracts from Ganoderma lucidum through activation of caspase-3.
Carcinoma
Induction of apoptosis in tumor cells by three naphthoquinone esters isolated from Thai medicinal plant: Rhinacanthus nasutus KURZ.
Carcinoma
Influence of CASP9 c.-1339A>G and CASP3 c.-1191A>G variants in outcome of patients with head and neck squamous cell carcinoma.
Carcinoma
Influence of survivin and caspase-3 on cell apoptosis and prognosis in gastric carcinoma.
Carcinoma
Inhibition of interferon-gamma-activated nuclear factor-kappa B by cyclosporin A: A possible mechanism for synergistic induction of apoptosis by interferon-gamma and cyclosporin A in gastric carcinoma cells.
Carcinoma
Inhibition of thromboxane synthase activity modulates bladder cancer cell responses to chemotherapeutic agents.
Carcinoma
Inhibition of tumour cell growth by hyperforin, a novel anticancer drug from St. John's wort that acts by induction of apoptosis.
Carcinoma
Inhibition of UV irradiation-induced oxidative stress and apoptotic biochemical changes in human epidermal carcinoma A431 cells by genistein.
Carcinoma
Interactions of the Hdm2/p53 and proteasome pathways may enhance the antitumor activity of bortezomib.
Carcinoma
Interleukin-1beta and Caspase-3 expression serve as independent prognostic markers for metastasis and survival in oral squamous cell carcinoma.
Carcinoma
Inverse correlation between apoptotic (Fas ligand, caspase-3) and angiogenic factors (VEGF, microvessel density) in squamous cell lung carcinomas.
Carcinoma
Inverse correlation of apoptotic and angiogenic markers in squamous cell carcinoma of the head and neck.
Carcinoma
Irinotecan/5-fluorouracil combination induces alterations in mitochondrial membrane potential and caspases on colon cancer cell lines.
Carcinoma
Khz (Fusion Product of Ganoderma lucidum and Polyporus umbellatus Mycelia) Induces Apoptosis in Human Colon Carcinoma HCT116 Cells, Accompanied by an Increase in Reactive Oxygen Species, Activation of Caspase 3, and Increased Intracellular Ca(2+).
Carcinoma
Leptin acts on neoplastic behavior and expression levels of genes related to hypoxia, angiogenesis, and invasiveness in oral squamous cell carcinoma.
Carcinoma
Lily extracts inhibit the proliferation of gastric carcinoma SGC-7901 cells by affecting cell cycle progression and apoptosis via the upregulation of caspase-3 and Fas proteins, and the downregulation of FasL protein.
Carcinoma
Livin and caspase-3 expression are negatively correlated in cervical squamous cell cancer.
Carcinoma
Lutein derived from marigold (Tagetes erecta) petals triggers ROS generation and activates Bax and caspase-3 mediated apoptosis of human cervical carcinoma (HeLa) cells.
Carcinoma
Lysosomal and mitochondrial permeabilization mediates zinc(II) cationic phthalocyanine phototoxicity.
Carcinoma
Maspin expression and its clinicopathological significance in tumorigenesis and progression of gastric cancer.
Carcinoma
Matrine induces apoptosis in gastric carcinoma cells via alteration of Fas/FasL and activation of caspase-3.
Carcinoma
Maytenus ilicifolia dry extract protects normal cells, induces apoptosis and regulates Bcl-2 in human cancer cells.
Carcinoma
Melanoma differentiation associated gene-7/interleukin-24 induces caspase-3 denitrosylation to facilitate the activation of cancer cell apoptosis.
Carcinoma
Melatonin potentiates the anti-tumour effect of pravastatin in rat mammary gland carcinoma model.
Carcinoma
Mercury-Induced Externalization of Phosphatidylserine and Caspase 3 Activation in Human Liver Carcinoma (HepG2) Cells.
Carcinoma
Methods for simultaneous measurement of apoptosis and cell surface phenotype of epithelial cells in effusions by flow cytometry.
Carcinoma
Microenvironment effects on promoting upregulation of matrix metalloproteinases in Bcl-2-overexpressing renal cell carcinoma as a response to doxorubicin treatment inducing the production of metastasis.
Carcinoma
miR-223 functions as a potent tumor suppressor of the Lewis lung carcinoma cell line by targeting insulin-like growth factor-1 receptor and cyclin-dependent kinase 2.
Carcinoma
Modeling hypoxia facilitates cancer cell survival through downregulation of p53 expression.
Carcinoma
Modulating effect of hesperetin on the molecular expression pattern of apoptotic and cell proliferative markers in 7,12-dimethylbenz(a)anthracene-induced oral carcinogenesis.
Carcinoma
Modulation of key signal transduction molecules by a novel peptide combination effective for the treatment of gastrointestinal carcinomas.
Carcinoma
Molecular cloning and characterization of a novel caspase-3 variant that attenuates apoptosis induced by proteasome inhibition.
Carcinoma
Multidomain Bcl-2 homolog Bax but not Bak mediates synergistic induction of apoptosis by TRAIL and 5-FU through the mitochondrial apoptosis pathway.
Carcinoma
Neuraminidase 1 regulates proliferation, apoptosis and the expression of Cadherins in mammary carcinoma cells.
Carcinoma
Nitric Oxide Causes Anoikis through Attenuation of E-Cadherin and Activation of Caspase-3 in Human Gastric Carcinoma AZ-521 Cells Infected with Mycoplasma hyorhinis.
Carcinoma
Novel quercetin encapsulated chitosan functionalized copper oxide nanoparticles as anti-breast cancer agent via regulating p53 in rat model.
Carcinoma
Nuclear hTERT immunohistochemical expression is associated with survival of patients with urothelial bladder cancer.
Carcinoma
Oral Squamous Cell Carcinoma From Users and Nonusers of Tobacco and Alcohol: Clinicopathologic Features and Immunoreactivity of VEGF, Caspase-3, and P53.
Carcinoma
Oregano demonstrates distinct tumour-suppressive effects in the breast carcinoma model.
Carcinoma
Over expression of inhibitor of caspase 3 activated deoxyribonuclease in human renal cell carcinoma cells enhances their resistance to cytotoxic chemotherapy in vivo.
Carcinoma
Overexpression of caspase-3s splice variant in locally advanced breast carcinoma is associated with poor response to neoadjuvant chemotherapy.
Carcinoma
Overexpression of COPS3 promotes clear cell renal cell carcinoma progression via regulation of Phospho-AKT(Thr308), Cyclin D1 and Caspase-3.
Carcinoma
p21 blocks irradiation-induced apoptosis downstream of mitochondria by inhibition of cyclin-dependent kinase-mediated caspase-9 activation.
Carcinoma
p53 inhibits alpha 6 beta 4 integrin survival signaling by promoting the caspase 3-dependent cleavage of AKT/PKB.
Carcinoma
Parathyroid hormone-related protein regulates apoptosis in lung cancer cells through protein kinase A.
Carcinoma
PARP1 and CASP3 gene expression in a patient with multiple head and neck squamous cell carcinoma and Parkinson disease.
Carcinoma
Pathobiological characteristics of intestinal and diffuse-type gastric carcinoma in Japan: an immunostaining study on the tissue microarray.
Carcinoma
Pathogenic characterization of Aeromonas salmonicida subsp. masoucida turbot isolate from China.
Carcinoma
Phenotypic characterization of BRCA1 and BRCA2 tumors based in a tissue microarray study with 37 immunohistochemical markers.
Carcinoma
Photodynamic Treatment Induces an Apoptotic Pathway Involving Calcium, Nitric Oxide, p53, p21-Activated Kinase 2, and c-Jun N-Terminal Kinase and Inactivates Survival Signal in Human Umbilical Vein Endothelial Cells.
Carcinoma
Phyllanthus urinaria triggers the apoptosis and Bcl-2 down-regulation in Lewis lung carcinoma cells.
Carcinoma
Physcion from marine-derived fungus Microsporum sp. induces apoptosis in human cervical carcinoma HeLa cells.
Carcinoma
Polymeric nanomedicine for tumor-targeted combination therapy to elicit synergistic genotoxicity against prostate cancer.
Carcinoma
Possible relations between oxidative damage and apoptosis in benign prostate hyperplasia and prostate cancer patients.
Carcinoma
Potential mechanism of phytochemical-induced apoptosis in human prostate adenocarcinoma cells: Therapeutic synergy in genistein and beta-lapachone combination treatment.
Carcinoma
Potential role of Notch1 signaling pathway in laryngeal squamous cell carcinoma cell line Hep-2 involving proliferation inhibition, cell cycle arrest, cell apoptosis, and cell migration.
Carcinoma
Procaspase 3 expression in ovarian carcinoma cells increases survivin transcription which can be countered with a dominant-negative mutant, survivin T34A; a combination gene therapy strategy.
Carcinoma
Procyanidin-rich extract of natural cocoa powder causes ROS-mediated caspase-3 dependent apoptosis and reduction of pro-MMP-2 in epithelial ovarian carcinoma cell lines.
Carcinoma
Prognostic relevance of c-Myc and caspase-3 for patients with non-small cell lung cancer.
Carcinoma
Prognostic significance of apoptotic cell death in bladder cancer: a tissue microarray study on 179 urothelial carcinomas from cystectomy specimens.
Carcinoma
Prognostic significance of caspase-3 expression in primary resected esophageal squamous cell carcinoma.
Carcinoma
Prognostic value of apoptotic markers in squamous cell carcinoma of the urinary bladder.
Carcinoma
Proliferation suppression and apoptosis of ovarian carcinoma cells induced by small interfering RNA against vascular endothelial growth factor.
Carcinoma
Proliferation, angiogenesis and apoptosis-associated proteins are molecular targets for chemoprevention of MNNG-induced gastric carcinogenesis by ethanolic Ocimum sanctum leaf extract.
Carcinoma
Proteomic analysis of antiproliferative effects by treatment of 5-fluorouracil in cervical cancer cells.
Carcinoma
Raised expression of the antiapoptotic protein ped/pea-15 increases susceptibility to chemically induced skin tumor development.
Carcinoma
Relationship between the expression of caspase-3 and the clinical outcome of patients with non-small cell lung cancer.
Carcinoma
Repression of caspase-3 and RNA-binding protein HuR cleavage by cyclooxygenase-2 promotes drug resistance in oral squamous cell carcinoma.
Carcinoma
Rhus coriaria L. (Sumac) Demonstrates Oncostatic Activity in the Therapeutic and Preventive Model of Breast Carcinoma.
Carcinoma
Riluzole induces apoptotic cell death in human prostate cancer cells via endoplasmic reticulum stress.
Carcinoma
Role of carbohydrate moiety of bleomycin-A2 in caspase-3 activation and internucleosomal chromatin fragmentation in apoptosis of laryngeal carcinoma cells.
Carcinoma
Screening the pathogenic genes and pathways related to DMBA (7,12-dimethylbenz[a]anthracene)-induced transformation of hamster oral mucosa from precancerous lesions to squamous cell carcinoma.
Carcinoma
Selective suppression of autocatalytic caspase-3 driven by two-step transcriptional amplified human telomerase reverse transcriptase promoter on ovarian carcinoma growth in vitro and in mice.
Carcinoma
Sequential combination therapy with flavopiridol and autocatalytic caspase-3 driven by amplified hTERT promoter synergistically suppresses human ovarian carcinoma growth in vitro and in mice.
Carcinoma
Shikonin-induced apoptosis involves caspase-3 activity in a human bladder cancer cell line (T24).
Carcinoma
Silibinin causes cell cycle arrest and apoptosis in human bladder transitional cell carcinoma cells by regulating CDKI-CDK-cyclin cascade, and caspase 3 and PARP cleavages.
Carcinoma
Single-cell microinjection assay indicates that 7-hydroxycoumarin induces rapid activation of caspase-3 in A549 cancer cells.
Carcinoma
Sodium salicylate induces apoptosis in HCT116 colorectal cancer cells through activation of p38MAPK.
Carcinoma
Study of the extraction process and in vivo inhibitory effect of ganoderma triterpenes in oral mucosa cancer.
Carcinoma
Surgical removal of the parametrial fat pads stimulates apoptosis and inhibits UVB-induced carcinogenesis in mice fed a high-fat diet.
Carcinoma
Synthetic isothiocyanate indole-3-ethyl isothiocyanate (homoITC) enhances sensitivity of human ovarian carcinoma cell lines A2780 and A2780/CP to cisplatin.
Carcinoma
Tannic acid, an inhibitor of poly(ADP-ribose) glycohydrolase, sensitizes ovarian carcinoma cells to cisplatin.
Carcinoma
Taxol-induced apoptosis in human SKOV3 ovarian and MCF7 breast carcinoma cells is caspase-3 and caspase-9 independent.
Carcinoma
The anti-tumour activity of rLj-RGD4, an RGD toxin protein from Lampetra japonica, on human laryngeal squamous carcinoma Hep-2 cells in nude mice.
Carcinoma
The antipsychotic agent flupentixol is a new PI3K inhibitor and potential anticancer drug for lung cancer.
Carcinoma
The apoptotic effect of apigenin on human gastric carcinoma cells through mitochondrial signal pathway.
Carcinoma
The C-terminal flanking peptide (CTFP) of progastrin inhibits apoptosis via a PI3-kinase-dependent pathway.
Carcinoma
The inhibitory effect of a novel organoselenium compound BBSKE on the tongue cancer Tca8113 in vitro and in vivo.
Carcinoma
The JNK, ERK and p53 pathways play distinct roles in apoptosis mediated by the antitumor agents vinblastine, doxorubicin, and etoposide.
Carcinoma
The mediating role of caspase-3 protease in the intracellular mechanism of genistein-induced apoptosis in human prostatic carcinoma cell lines, DU145 and LNCaP.
Carcinoma
The pattern of CPP32/caspase-3 expression reflects the biological behavior of the human pancreatic duct cell tumors.
Carcinoma
The primary growth of laryngeal squamous cell carcinoma cells in vitro is effectively supported by paired cancer-associated fibroblasts alone.
Carcinoma
The sensitivity of head and neck carcinoma cells to statins is related to the expression of their Ras expression status, and statin-induced apoptosis is mediated via suppression of the Ras/ERK and Ras/mTOR pathways.
Carcinoma
Therapeutic efficacy of natural dipeptide carnosine against human cervical carcinoma cells.
Carcinoma
Three apoptotic genes are upregulated in a patient with Alzheimer's disease and well-differentiated squamous cell carcinoma.
Carcinoma
TRAIL sensitizes for ionizing irradiation-induced apoptosis through an entirely Bax-dependent mitochondrial cell death pathway.
Carcinoma
Transfection of mutant p53 gene depresses X-ray- or CDDP-induced apoptosis in a human squamous cell carcinoma of the head and neck.
Carcinoma
Tumor-specific cytotoxic activity of 1,2,3,4-tetrahydroisoquinoline derivatives against human oral squamous cell carcinoma cell lines.
Carcinoma
Two new glycosides isolated from Sapindus mukorossi fruits: effects on cell apoptosis and caspase-3 activation in human lung carcinoma cells.
Carcinoma
Tyrosine-nitration of caspase 3 and cytochrome c does not suppress apoptosis induction in squamous cell carcinoma cells.
Carcinoma
Upregulation of CASP genes in human tumor cells undergoing etoposide-induced apoptosis.
Carcinoma
Upregulation of caspase-3 expression in esophageal cancer correlates with favorable prognosis: an immunohistochemical study from a high incidence area in northern China.
Carcinoma
Use of combined apoptosis biomarkers for prediction of bladder cancer recurrence and mortality after radical cystectomy.
Carcinoma
YY1-mediated PTEN dephosphorylation antagonizes IR-induced DNA repair contributing to tongue squamous cell carcinoma radiosensitization.
Carcinoma
Ziyuglycoside II-induced apoptosis in human gastric carcinoma BGC-823 cells by regulating Bax/Bcl-2 expression and activating caspase-3 pathway.
Carcinoma
[Apoptosis modulation by PMA occurs independently of TsPO expression in squamous cell carcinoma cells].
Carcinoma
[Construction of autocatalytic caspase-3 and its effects of inducing apoptosis in human ovarian carcinoma]
Carcinoma
[Construction of autocatalytic caspase-3 driven by amplified human telomerase reverse transcriptase promoter and its enhanced efficacy of inducing apoptosis in human ovarian carcinoma]
Carcinoma
[Down-regulation of Caspase-3 expression in precancerous lesions and its relation to gastric carcinogenesis]
Carcinoma
[Effect of human trophoblast cell-surface antigen 2 gene expression by RNA interference on proliferation and apoptosis of tongue squamous cell carcinoma and its mechanism].
Carcinoma
[Effect of the change of caspase-3 activity on the neoadjuvant chemotherapy-induced apoptosis of large-intestinal carcinoma cells]
Carcinoma
[Effects of salinomycin on proliferation and apoptosis of oral squamous cell carcinoma].
Carcinoma
[Expression and clinical significance of caspase-3,survivin and k-ras in non-small cell lung cancer.]
Carcinoma
[Expression and clinical significance of Xiap and Caspase-3 protien in primary epithelia ovarian cancer].
Carcinoma
[Expression and prognostic significance of survivin and caspase-3 in esophageal squamous-cell carcinoma and their relationship with HSPs expression]
Carcinoma
[Expression and significance of PTEN and caspase-3 in laryngeal squamous cell carcinoma]
Carcinoma
[Expression of AIF and caspase-3 in colorectal carcinoma, adenoma, and normal mucosa and its correlation]
Carcinoma
[Expression of apoptosis and proliferation related genes in carcinogenesis of lung squamous cell carcinoma in rats]
Carcinoma
[Expression of caspase 3 in gastric carcinoma and atypical proliferation and its association with apoptosis]
Carcinoma
[Expression of Caspase-3 and Bcl-2 in bladder transitional carcinoma and their significance]
Carcinoma
[Expression of livin in lung cancer tissue and its relationship with the expression of caspase-3.]
Carcinoma
[Expression of Survivin mRNA and Caspase-3 mRNA and their correlation in tongue squamous cell carcinoma]
Carcinoma
[Expression of Survivin, Caspase-3 and p53 in surgical margin of laryngeal squamous cell carcinoma and their relationship]
Carcinoma
[Expression of survivin, caspase-3 in oral precancerous lesions and oral squamous-cell carcinoma.]
Carcinoma
[FUNCTIONAL ACTIVITY OF EHRLICH CARCINOMA CELLS AFTER TREATMENT WITH HYBRID NANOCOMPLEXES CONTAINING ORTHOVANADATES OF RARE-EARTH ELEMENTS, CHOLESTEROL AND LUMINESCENT DYE].
Carcinoma
[Microwave Hyperthermia Combined with Gemcitabine Inhibits Proliferation ?and Induces Apoptosis of Human Lung Squamous Carcinoma Cells].
Carcinoma
[Roles of cyclooxygenase-2 and caspase-3 expression in pathogenesis of lung carcinoma: an experiment with rats]
Carcinoma
[Study of apoptosis related factors regulatory mechanism of resveratrol to human skin squamous cell carcinoma A431 xenograft in nude mice].
Carcinoma
[Synergism of antitumor effects on ovarian carcinoma using autocatalytic caspase-3 combined with flavopiridol].
Carcinoma
[The effect of tanshinone ?A potentiates the effects of Cisplatin in Fadu cells in vitro through downregulation of survivin].
Carcinoma
[The expression of caspase-3, bFGF and MVD in laryngeal squamous cell carcinoma and the relationship among them].
Carcinoma
[The relationship between caspase-3 expression and cell proliferation in rat lung squamous cell carcinoma.]
Carcinoma in Situ
Prolonged survival and delayed progression of pancreatic intraepithelial neoplasia in LSL-KrasG12D/+;Pdx-1-Cre mice by vitamin E ?-tocotrienol.
Carcinoma, Adenoid Cystic
Activation of caspase-3 noninvolved in the bystander effect of the herpes simplex virus thymidine kinase gene/ganciclovir (HSV-tk/GCV) system.
Carcinoma, Basal Cell
Caspase-3, p53 and Bcl-2 expression in basal cell carcinoma of the eyelid.
Carcinoma, Basal Cell
Expression of the pro-apoptotic caspase 3/CPP32 in cutaneous basal and squamous cell carcinomas.
Carcinoma, Ductal
A novel, patient-specific mathematical pathology approach for assessment of surgical volume: Application to ductal carcinoma in situ of the breast.
Carcinoma, Ductal
A novel, patient-specific mathematical pathology approach for assessment of surgical volume: application to ductal carcinoma in situ of the breast.
Carcinoma, Ductal
A novel, patient-specific mathematical pathology approach for assessment of surgical volume: Application to ductal carcinoma in situ of the breast.
Carcinoma, Ductal
Expression of cyclooxygenase-2 and its relation to histological grade, inducible nitric oxide synthase, matrix metalloproteinase-2, CD-34, Caspase-3, and CD8 in invasive ductal carcinoma of the breast.
Carcinoma, Ductal
Extra copies of chromosomes 16 and X in invasive breast carcinomas are related to aggressive phenotype and poor prognosis.
Carcinoma, Ehrlich Tumor
Apoptosis induced by 1'-acetoxychavicol acetate in Ehrlich ascites tumor cells is associated with modulation of polyamine metabolism and caspase-3 activation.
Carcinoma, Ehrlich Tumor
Pinpointing differences in cisplatin-induced apoptosis in adherent and non-adherent cancer cells.
Carcinoma, Embryonal
Activation of calpain in cultured neurons overexpressing Alzheimer amyloid precursor protein.
Carcinoma, Embryonal
bFGF inhibits the activation of caspase-3 and apoptosis of P19 embryonal carcinoma cells during neuronal differentiation.
Carcinoma, Embryonal
Cell death induced by a caspase-cleaved transmembrane fragment of the Alzheimer amyloid precursor protein.
Carcinoma, Embryonal
ER stress induces caspase-8 activation, stimulating cytochrome c release and caspase-9 activation.
Carcinoma, Embryonal
[Molecular mechanisms of differentiation and death of human neurons: with special reference to necdin and APP]
Carcinoma, Hepatocellular
15-Deoxy-delta12,14-prostaglandin J2, a ligand for peroxisome proliferators-activated receptor-gamma, induces apoptosis in human hepatoma cells.
Carcinoma, Hepatocellular
A novel mechanism of hepatocellular carcinoma cell apoptosis induced by lupeol via Brain-Derived Neurotrophic Factor Inhibition and Glycogen Synthase Kinase 3 beta reactivation.
Carcinoma, Hepatocellular
A standardized extract from Paeonia lactiflora and Astragalus membranaceus induces apoptosis and inhibits the proliferation, migration and invasion of human hepatoma cell lines.
Carcinoma, Hepatocellular
Active caspase 3 and DNA fragmentation as markers for apoptotic cell death in primary and metastatic liver tumours.
Carcinoma, Hepatocellular
Adenosine-induced caspase-3 activation by tuning Bcl-X(L)/DIABLO/IAP expression in HuH-7 human hepatoma cells.
Carcinoma, Hepatocellular
Adenovirus-mediated transfer of caspase-3 with Fas ligand induces drastic apoptosis in U-373MG glioma cells.
Carcinoma, Hepatocellular
Alpha fetoprotein is a novel protein-binding partner for caspase-3 and blocks the apoptotic signaling pathway in human hepatoma cells.
Carcinoma, Hepatocellular
An integrated genomic and proteomic approach to identify signatures of endosulfan exposure in hepatocellular carcinoma cells.
Carcinoma, Hepatocellular
Analysis of in vivo patterns of caspase 3 gene expression in primary hepatocellular carcinoma and its relationship to p21(WAF1) expression and hepatic apoptosis.
Carcinoma, Hepatocellular
Anti-proliferative effects of cucurmosin on human hepatoma HepG2 cells.
Carcinoma, Hepatocellular
Antiapoptotic effect of haem oxygenase-1 induced by nitric oxide in experimental solid tumour.
Carcinoma, Hepatocellular
Antisense oligonucleotides targeting midkine inhibit tumor growth in an in situ human hepatocellular carcinoma model.
Carcinoma, Hepatocellular
Apoptosis-inducing activity of the antimicrobial peptide cecropin of Musca domestica in human hepatocellular carcinoma cell line BEL-7402 and the possible mechanism.
Carcinoma, Hepatocellular
Aspirin reduces the apoptotic effect of etoposide via Akt activation and up-regulation of p21cip.
Carcinoma, Hepatocellular
Autophagy, apoptosis, vitamin D, and vitamin D receptor in hepatocellular carcinoma associated with hepatitis C virus.
Carcinoma, Hepatocellular
Baicalin and the liver-gut system: Pharmacological bases explaining its therapeutic effects.
Carcinoma, Hepatocellular
Biotechnological Applications for the Sustainable Use of Marine By-products: In Vitro Antioxidant and Pro-apoptotic Effects of Astaxanthin Extracted with Supercritical CO2 from Parapeneus longirostris.
Carcinoma, Hepatocellular
Blockade of Janus kinase-2 signaling ameliorates mouse liver damage due to ischemia and reperfusion.
Carcinoma, Hepatocellular
Caspase 3 specifically cleaves p21WAF1/CIP1 in the earlier stage of apoptosis in SK-HEP-1 human hepatoma cells.
Carcinoma, Hepatocellular
Caspase 3, periodically expressed and activated at G2/M transition, is required for nocodazole-induced mitotic checkpoint.
Carcinoma, Hepatocellular
Caspase activity during cell stasis: avoidance of apoptosis in an invertebrate extremophile, Artemia franciscana.
Carcinoma, Hepatocellular
Caspase-3 activation as a key factor for HBx-transformed cell death.
Carcinoma, Hepatocellular
Caspase-3-dependent protein kinase C delta activity is required for the progression of Ginsenoside-Rh2-induced apoptosis in SK-HEP-1 cells.
Carcinoma, Hepatocellular
Caspase-dependent and independent cell death in rat hepatoma 5123tc cells.
Carcinoma, Hepatocellular
Clinacanthus nutans (Burm. f.) Lindau Ethanol Extract Inhibits Hepatoma in Mice through Upregulation of the Immune Response.
Carcinoma, Hepatocellular
Comparison of Pregnane X Receptor Antagonists for Enhancing the Antitumor Effect of Cisplatin.
Carcinoma, Hepatocellular
Conditionally replicative adenovirus vector carrying TRAIL gene for enhanced oncolysis of human hepatocellular carcinoma.
Carcinoma, Hepatocellular
Cucurbitacin D isolated from Trichosanthes kirilowii induces apoptosis in human hepatocellular carcinoma cells in vitro.
Carcinoma, Hepatocellular
Cytotoxicity of Moringa oleifera fruits on human liver cancer and molecular docking analysis of bioactive constituents against caspase-3 enzyme.
Carcinoma, Hepatocellular
Dioscin suppresses hepatocellular carcinoma tumor growth by inducing apoptosis and regulation of TP53, BAX, BCL2 and cleaved CASP3.
Carcinoma, Hepatocellular
DLC1 suppresses distant dissemination of human hepatocellular carcinoma cells in nude mice through reduction of RhoA GTPase activity, actin cytoskeletal disruption and down-regulation of genes involved in metastasis.
Carcinoma, Hepatocellular
Down-modulation of heat shock protein 70 and up-modulation of Caspase-3 during schisandrin B-induced apoptosis in human hepatoma SMMC-7721 cells.
Carcinoma, Hepatocellular
Effect of targeted magnetic nanoparticles containing 5-FU on expression of bcl-2, bax and caspase 3 in nude mice with transplanted human liver cancer.
Carcinoma, Hepatocellular
Effects and mechanism of suberoylanilide hydroxamic acid on the proliferation and apoptosis of human hepatoma cell line Bel-7402.
Carcinoma, Hepatocellular
Effects of an oral iron chelator, deferasirox, on advanced hepatocellular carcinoma.
Carcinoma, Hepatocellular
Effects of soy isoflavones on apoptosis induction and G2-M arrest in human hepatoma cells involvement of caspase-3 activation, Bcl-2 and Bcl-XL downregulation, and Cdc2 kinase activity.
Carcinoma, Hepatocellular
Ethanol extracts of Cinnamomum kanehirai Hayata leaves induce apoptosis in human hepatoma cell through caspase-3 cascade.
Carcinoma, Hepatocellular
Exogenous hydrogen sulfide exerts proliferation/anti-apoptosis/angiogenesis/migration effects via amplifying the activation of NF-?B pathway in PLC/PRF/5 hepatoma cells.
Carcinoma, Hepatocellular
Expression and prognostic significance of osteopontin and caspase-3 in hepatocellular carcinoma patients after curative resection.
Carcinoma, Hepatocellular
Expression of caspase-3 and hypoxia inducible factor 1? in hepatocellular carcinoma complicated by hemorrhage and necrosis.
Carcinoma, Hepatocellular
Expression of TLR-2 in hepatocellular carcinoma is associated with tumour proliferation, angiogenesis and Caspase-3 expression.
Carcinoma, Hepatocellular
FTY720 induces apoptosis of human hepatoma cell lines through PI3-K-mediated Akt dephosphorylation.
Carcinoma, Hepatocellular
Functional absence of FADD in PLC/PRF/5 hepatoma cells: possible involvement in the transformation to hepatoma in HBV-infected hepatocytes.
Carcinoma, Hepatocellular
Functional role of caspases in sphingosine-induced apoptosis in human hepatoma cells.
Carcinoma, Hepatocellular
Gene transfer of constitutively active caspase-3 induces apoptosis in a human hepatoma cell line.
Carcinoma, Hepatocellular
Globular adiponectin inhibits ethanol-induced apoptosis in HepG2 cells through heme oxygenase-1 induction.
Carcinoma, Hepatocellular
HBP1-mediated transcriptional repression of AFP inhibits hepatoma progression.
Carcinoma, Hepatocellular
HBx-upregulated lncRNA UCA1 promotes cell growth and tumorigenesis by recruiting EZH2 and repressing p27Kip1/CDK2 signaling.
Carcinoma, Hepatocellular
High serum caspase-3 levels in hepatocellular carcinoma prior to liver transplantation and high mortality risk during the first year after liver transplantation.
Carcinoma, Hepatocellular
Identification of components of grape powder with anti-apoptotic effects.
Carcinoma, Hepatocellular
IFN-gamma induces cell death in human hepatoma cells through a TRAIL/death receptor-mediated apoptotic pathway.
Carcinoma, Hepatocellular
In vitro and in vivo effects and mechanisms of celecoxib-induced growth inhibition of human hepatocellular carcinoma cells.
Carcinoma, Hepatocellular
Induction of apoptosis in human hepatoma cells by mycelia of Antrodia camphorata in submerged culture.
Carcinoma, Hepatocellular
Inhibitory effect of all-trans retinoic acid on human hepatocellular carcinoma cell proliferation.
Carcinoma, Hepatocellular
INHIBITORY EFFECT OF CHITOSAN OLIGOSACCHARIDE ON HUMAN HEPATOMA CELLS IN VITRO.
Carcinoma, Hepatocellular
Inhibitory Effects of ?,?-Dimethylacrylshikonin on Hepatocellular Carcinoma In Vitro and In Vivo.
Carcinoma, Hepatocellular
Involvement of p38 mitogen-activated protein kinase pathway in honokiol-induced apoptosis in a human hepatoma cell line (hepG2).
Carcinoma, Hepatocellular
Involvement of the prostaglandin E receptor EP2 in paeoniflorin-induced human hepatoma cell apoptosis.
Carcinoma, Hepatocellular
Isolation of 4,4'-bond secalonic acid D from the marine-derived fungus Penicillium oxalicum with inhibitory property against hepatocellular carcinoma.
Carcinoma, Hepatocellular
Lentiviral-mediated Smad4 RNAi induced anti-proliferation by p16 up-regulation and apoptosis by caspase 3 down-regulation in hepatoma SMMC-7721 cells.
Carcinoma, Hepatocellular
Let-7a microRNA suppresses therapeutics-induced cancer cell death by targeting caspase-3.
Carcinoma, Hepatocellular
LncRNA NEAT1 regulates proliferation, apoptosis and invasion of liver cancer.
Carcinoma, Hepatocellular
Lysionotin induces apoptosis of hepatocellular carcinoma cells via caspase-3 mediated mitochondrial pathway.
Carcinoma, Hepatocellular
Mechanisms of pseudolaric Acid B-induced apoptosis in bel-7402 cell lines.
Carcinoma, Hepatocellular
Melatonin maximizes the therapeutic potential of non-preconditioned MSCs in a DEN-induced rat model of HCC.
Carcinoma, Hepatocellular
Metformin and epothilone A treatment up regulate pro-apoptotic PARP-1, Casp-3 and H2AX genes and decrease of AKT kinase level to control cell death of human hepatocellular carcinoma and ovary adenocarcinoma cells.
Carcinoma, Hepatocellular
MicroRNA-34a suppresses aggressiveness of hepatocellular carcinoma by modulating E2F1, E2F3, and Caspase-3.
Carcinoma, Hepatocellular
Midkine protects hepatocellular carcinoma cells against TRAIL-mediated apoptosis through down-regulation of caspase-3 activity.
Carcinoma, Hepatocellular
Miltirone induces cell death in hepatocellular carcinoma cell through GSDME-dependent pyroptosis.
Carcinoma, Hepatocellular
MK5 is degraded in response to doxorubicin and negatively regulates doxorubicin-induced apoptosis in hepatocellular carcinoma cells.
Carcinoma, Hepatocellular
Momordin Ic induces HepG2 cell apoptosis through MAPK and PI3K/Akt-mediated mitochondrial pathways.
Carcinoma, Hepatocellular
Nano-Pulse Stimulation is a physical modality that can trigger immunogenic tumor cell death.
Carcinoma, Hepatocellular
Nanoparticles inhibit cancer cell invasion and enhance antitumor efficiency by targeted drug delivery via cell surface-related GRP78.
Carcinoma, Hepatocellular
NET-1 promotes invasion, adhesion and growth of hepatocellular carcinoma by regulating the expression of BAX, caspase 3, caspase 8 and BCL2.
Carcinoma, Hepatocellular
Overexpression of bcl-2 enhances LIGHT- and interferon-gamma -mediated apoptosis in Hep3BT2 cells.
Carcinoma, Hepatocellular
P38MAPK regulates caspase-3 by binding to caspase-3 in nucleus of human hepatoma Bel-7402 cells during anti-Fas antibody- and actinomycin D-induced apoptosis.
Carcinoma, Hepatocellular
Paeoniflorin, a Natural Product With Multiple Targets in Liver Diseases-A Mini Review.
Carcinoma, Hepatocellular
PF-04691502 triggers cell cycle arrest, apoptosis and inhibits the angiogenesis in hepatocellular carcinoma cells.
Carcinoma, Hepatocellular
Plumbagin promotes human hepatoma SMMC-7721 cell apoptosis via caspase-3/vimentin signal-mediated EMT.
Carcinoma, Hepatocellular
Potentiated anticancer effects on hepatoma cells by the retinoid adapalene.
Carcinoma, Hepatocellular
Pro-apoptotic Sorafenib signaling in murine hepatocytes depends on malignancy and is associated with PUMA expression in vitro and in vivo.
Carcinoma, Hepatocellular
Rapamycin inhibits cell growth by induction of apoptosis on hepatocellular carcinoma cells in vitro.
Carcinoma, Hepatocellular
Redox cycling of copper by coumarin-di(2-picolyl)amine hybrid molecule leads to ROS-mediated modulation of redox scavengers, DNA damage and cell death in diethylnitrosamine induced hepatocellular carcinoma.
Carcinoma, Hepatocellular
Reduced expression of ICE/caspase1 and CPP32/caspase3 in human hepatocellular carcinoma.
Carcinoma, Hepatocellular
Regulatory role of autophagy in globular adiponectin-induced apoptosis in cancer cells.
Carcinoma, Hepatocellular
Resistance to Fas-mediated apoptosis: activation of caspase 3 is regulated by cell cycle regulator p21WAF1 and IAP gene family ILP.
Carcinoma, Hepatocellular
Role of AKT kinase in sphingosine-induced apoptosis in human hepatoma cells.
Carcinoma, Hepatocellular
Ropivacaine promotes apoptosis of hepatocellular carcinoma cells through damaging mitochondria and activating caspase-3 activity.
Carcinoma, Hepatocellular
Scutellaria barbate extract induces apoptosis of hepatoma H22 cells via the mitochondrial pathway involving caspase-3.
Carcinoma, Hepatocellular
Selective accumulation and growth inhibition of hybrid liposomes to human hepatocellular carcinoma cells in relation to fluidity of plasma membranes.
Carcinoma, Hepatocellular
Selenoprotein Genes Exhibit Differential Expression Patterns Between Hepatoma HepG2 and Normal Hepatocytes LO2 Cell Lines.
Carcinoma, Hepatocellular
Structural basis for alpha fetoprotein-mediated inhibition of caspase-3 activity in hepatocellular carcinoma cells.
Carcinoma, Hepatocellular
Structural re-positioning, in silico molecular modelling, oxidative degradation, and biological screening of linagliptin as adenosine 3 receptor (ADORA3) modulators targeting hepatocellular carcinoma.
Carcinoma, Hepatocellular
Suppression of endogenous hydrogen sulfide contributes to the radiation-induced bystander effects on hypoxic HepG2 cells.
Carcinoma, Hepatocellular
Suppression of GST-P by treatment with glutathione-doxorubicin conjugate induces potent apoptosis in rat hepatoma cells.
Carcinoma, Hepatocellular
Synergic effect of 3'-azido-3'-deoxythymidine and arsenic trioxide in suppressing hepatoma cells.
Carcinoma, Hepatocellular
Tanshinone IIA inhibits human hepatocellular carcinoma J5 cell growth by increasing Bax and caspase 3 and decreasing CD31 expression in vivo.
Carcinoma, Hepatocellular
Targeting survivin with prodigiosin isolated from cell wall of Serratia marcescens induces apoptosis in hepatocellular carcinoma cells.
Carcinoma, Hepatocellular
The effects of modulation of gamma-glutamyl transpeptidase activity in HepG2 cells on thiol homeostasis and caspase-3-activity.
Carcinoma, Hepatocellular
The soluble form of human leukocyte antigen class I antigen causes apoptosis on hepatocellular carcinoma cell lines.
Carcinoma, Hepatocellular
Tuning of apoptosis-mediator gene transcription in HepG2 human hepatoma cells through an adenosine signal.
Carcinoma, Hepatocellular
Wogonin and fisetin induction of apoptosis through activation of caspase 3 cascade and alternative expression of p21 protein in hepatocellular carcinoma cells SK-HEP-1.
Carcinoma, Hepatocellular
Xanthatin induces apoptosis by activating endoplasmic reticulum stress in hepatoma cells.
Carcinoma, Hepatocellular
[Combination of triptolide with sodium cantharidinate synergistically enhances apoptosis on? hepatoma cell line 7721].
Carcinoma, Hepatocellular
[Effects of NK-104 on apoptosis and caspase-3 activity in hepatocellular carcinoma cells]
Carcinoma, Hepatocellular
[Role of caspase-8 and caspase-3 in hepatoma cells apoptosis induced by 5-fluorouracil]
Carcinoma, Hepatocellular
[Role of proteins in Fas-mediated apoptosis in tumor cells and lymphocytes co-cultured in vitro]
Carcinoma, Hepatocellular
[The role of caspase-3 in rapamycin-induced apoptosis of hepatocellular carcinoma BEL-7402 cells]
Carcinoma, Intraductal, Noninfiltrating
A novel, patient-specific mathematical pathology approach for assessment of surgical volume: Application to ductal carcinoma in situ of the breast.
Carcinoma, Intraductal, Noninfiltrating
A novel, patient-specific mathematical pathology approach for assessment of surgical volume: application to ductal carcinoma in situ of the breast.
Carcinoma, Intraductal, Noninfiltrating
A novel, patient-specific mathematical pathology approach for assessment of surgical volume: Application to ductal carcinoma in situ of the breast.
Carcinoma, Intraductal, Noninfiltrating
Modulation of the immune microenvironment of high-risk ductal carcinoma in situ by intralesional pembrolizumab injection.
Carcinoma, Large Cell
[Expression of livin in lung cancer tissue and its relationship with the expression of caspase-3.]
Carcinoma, Lewis Lung
miR-223 functions as a potent tumor suppressor of the Lewis lung carcinoma cell line by targeting insulin-like growth factor-1 receptor and cyclin-dependent kinase 2.
Carcinoma, Lewis Lung
Phyllanthus urinaria triggers the apoptosis and Bcl-2 down-regulation in Lewis lung carcinoma cells.
Carcinoma, Mucoepidermoid
Altered expression of apoptosis-regulating miRNAs in salivary gland tumors suggests their involvement in salivary gland tumorigenesis.
Carcinoma, Non-Small-Cell Lung
Activation of caspase-3 and cleavage of Rb are associated with p16-mediated apoptosis in human non-small cell lung cancer cells.
Carcinoma, Non-Small-Cell Lung
Adenoviral Bid overexpression induces caspase-dependent cleavage of truncated Bid and p53-independent apoptosis in human non-small cell lung cancers.
Carcinoma, Non-Small-Cell Lung
Assessment of M867, a selective caspase-3 inhibitor, in an orthotopic mouse model for non-small cell lung carcinoma.
Carcinoma, Non-Small-Cell Lung
Association of CASP3 polymorphism with hematologic toxicity in patients with advanced non-small-cell lung carcinoma treated with platinum-based chemotherapy.
Carcinoma, Non-Small-Cell Lung
Caspase cleavage of Mcl-1 impairs its anti-apoptotic activity and proteasomal degradation in non-small lung cancer cells.
Carcinoma, Non-Small-Cell Lung
Caspase-3 knockout attenuates radiation-induced tumor repopulation via impairing the ATM/p53/Cox-2/PGE2 pathway in non-small cell lung cancer.
Carcinoma, Non-Small-Cell Lung
Clinicopathological significance of cathepsin D expression in non-small cell lung cancer is conditional on apoptosis-associated protein phenotype: an immunohistochemistry study.
Carcinoma, Non-Small-Cell Lung
Combretastatin CA-4 and combretastatin derivative induce mitotic catastrophe dependent on spindle checkpoint and caspase-3 activation in non-small cell lung cancer cells.
Carcinoma, Non-Small-Cell Lung
Defective caspase-3 relocalization in non-small cell lung carcinoma.
Carcinoma, Non-Small-Cell Lung
Expression of Caspase-3 and c-myc in Non-Small Cell Lung Cancer.
Carcinoma, Non-Small-Cell Lung
HLJ1 is a novel caspase-3 substrate and its expression enhances UV-induced apoptosis in non-small cell lung carcinoma.
Carcinoma, Non-Small-Cell Lung
Inhibition of autophagy by autophagic inhibitors enhances apoptosis induced by bortezomib in non-small cell lung cancer cells.
Carcinoma, Non-Small-Cell Lung
Inhibition of nuclear factor kappaB chemosensitizes non-small cell lung cancer through cytochrome c release and caspase activation.
Carcinoma, Non-Small-Cell Lung
Involvement of Bcl-2 family, cytochrome c and caspase 3 in induction of apoptosis by beauvericin in human non-small cell lung cancer cells.
Carcinoma, Non-Small-Cell Lung
Involvement of CASP3 promoter polymorphism (-1337 C?>?G) in the development and progression of non-small cell lung cancer.
Carcinoma, Non-Small-Cell Lung
Measurement of conatumumab-induced apoptotic activity in tumors by fine needle aspirate sampling.
Carcinoma, Non-Small-Cell Lung
MiR-222-3p Promotes Cell Proliferation and Inhibits Apoptosis by Targeting PUMA (BBC3) in Non-Small Cell Lung Cancer.
Carcinoma, Non-Small-Cell Lung
Mitogen-activated protein kinase phosphatase-1 modulated JNK activation is critical for apoptosis induced by inhibitor of epidermal growth factor receptor-tyrosine kinase.
Carcinoma, Non-Small-Cell Lung
Paclitaxel-induced apoptosis in non-small cell lung cancer cell lines is associated with increased caspase-3 activity.
Carcinoma, Non-Small-Cell Lung
Prognostic assessment of apoptotic gene polymorphisms in non-small cell lung cancer in Chinese.
Carcinoma, Non-Small-Cell Lung
Prognostic relevance of c-Myc and caspase-3 for patients with non-small cell lung cancer.
Carcinoma, Non-Small-Cell Lung
Relationship between the expression of caspase-3 and the clinical outcome of patients with non-small cell lung cancer.
Carcinoma, Non-Small-Cell Lung
Replication-dependent ?-H2AX formation is involved in docetaxel-induced apoptosis in NSCLC A549 cells.
Carcinoma, Non-Small-Cell Lung
RNAi targeting STMN alleviates the resistance to taxol and collectively contributes to down regulate the malignancy of NSCLC cells in vitro and in vivo.
Carcinoma, Non-Small-Cell Lung
Role of XIAP in inhibiting cisplatin-induced caspase activation in non-small cell lung cancer cells: a small molecule Smac mimic sensitizes for chemotherapy-induced apoptosis by enhancing caspase-3 activation.
Carcinoma, Non-Small-Cell Lung
Sulindac enhances adenoviral vector expressing mda-7/IL-24-mediated apoptosis in human lung cancer.
Carcinoma, Non-Small-Cell Lung
Triptolide suppresses the in vitro and in vivo growth of lung cancer cells by targeting hyaluronan-CD44/RHAMM signaling.
Carcinoma, Non-Small-Cell Lung
[Expression of apoptosis and proliferation related genes in carcinogenesis of lung squamous cell carcinoma in rats]
Carcinoma, Non-Small-Cell Lung
[Expression of NF-kappa B and AP-1 in non-small cell lung cancer.]
Carcinoma, Non-Small-Cell Lung
[Expressions of survivin and caspase-3 in human non-small cell lung cancer and their relationship with cell apoptosis.]
Carcinoma, Ovarian Epithelial
Myeloperoxidase serves as a redox switch that regulates apoptosis in epithelial ovarian cancer.
Carcinoma, Ovarian Epithelial
Procyanidin-rich extract of natural cocoa powder causes ROS-mediated caspase-3 dependent apoptosis and reduction of pro-MMP-2 in epithelial ovarian carcinoma cell lines.
Carcinoma, Ovarian Epithelial
[Expression and clinical significance of Xiap and Caspase-3 protien in primary epithelia ovarian cancer].
Carcinoma, Papillary
Cytophotometric expression of Caspase-3 in papillary thyroid carcinoma in nodular goiter colloid.
Carcinoma, Renal Cell
Activation of caspase-3 in renal cell carcinoma cells by anthracyclines or 5-fluorouracil.
Carcinoma, Renal Cell
Angelicin potentiates TRAIL-induced apoptosis in renal carcinoma Caki cells through activation of caspase 3 and down-regulation of c-FLIP expression.
Carcinoma, Renal Cell
Antitumor effects of a polypeptide isolated from Tegillarca granosa linnaeus and the related molecular mechanism.
Carcinoma, Renal Cell
Caspase 3 as a Novel Marker to Distinguish Chromophobe Renal Cell Carcinoma from Oncocytoma.
Carcinoma, Renal Cell
Data on cell survival, apoptosis, ceramide metabolism and oxidative stress in A-494 renal cell carcinoma cell line treated with hesperetin and hesperetin-7-O-acetate.
Carcinoma, Renal Cell
Dimethoxycurcumin, a structural analogue of curcumin, induces apoptosis in human renal carcinoma caki cells through the production of reactive oxygen species, the release of cytochrome C, and the activation of caspase-3.
Carcinoma, Renal Cell
Efficacy of carnosine on activation of caspase 3 and human renal carcinoma cell inhibition.
Carcinoma, Renal Cell
Knockdown of ZFX suppresses renal carcinoma cell growth and induces apoptosis.
Carcinoma, Renal Cell
Microenvironment effects on promoting upregulation of matrix metalloproteinases in Bcl-2-overexpressing renal cell carcinoma as a response to doxorubicin treatment inducing the production of metastasis.
Carcinoma, Renal Cell
Over expression of inhibitor of caspase 3 activated deoxyribonuclease in human renal cell carcinoma cells enhances their resistance to cytotoxic chemotherapy in vivo.
Carcinoma, Renal Cell
Overexpression of COPS3 promotes clear cell renal cell carcinoma progression via regulation of Phospho-AKT(Thr308), Cyclin D1 and Caspase-3.
Carcinoma, Small Cell
Bioengineering functional copolymers. XIV. Synthesis and interaction of poly(N-isopropylacrylamide-co-3,4-dihydro-2H-pyran-alt-maleic anhydride)s with SCLC cancer cells.
Carcinoma, Squamous Cell
Analysis of expression of p63 and caspase-3 and their predictive value in patients with squamous cell carcinoma of maxillary sinus.
Carcinoma, Squamous Cell
Apoptosis and anti-apoptotic heat shock proteins in canine cutaneous infundibular keratinizing acanthomas and squamous cell carcinomas.
Carcinoma, Squamous Cell
Argpyrimidine-modified Heat shock protein 27 in human non-small cell lung cancer: a possible mechanism for evasion of apoptosis.
Carcinoma, Squamous Cell
Association of Casp3 microRNA Target Site (1049216) SNP With the Risk and Progress of Cervical Squamous Cell Carcinoma.
Carcinoma, Squamous Cell
Berberine inhibits growth, induces G1 arrest and apoptosis in human epidermoid carcinoma A431 cells by regulating Cdki-Cdk-cyclin cascade, disruption of mitochondrial membrane potential and cleavage of caspase 3 and PARP.
Carcinoma, Squamous Cell
Capsaicin induced cell cycle arrest and apoptosis in human esophagus epidermoid carcinoma CE 81T/VGH cells through the elevation of intracellular reactive oxygen species and Ca2+ productions and caspase-3 activation.
Carcinoma, Squamous Cell
CASP3 polymorphisms and risk of squamous cell carcinoma of the head and neck.
Carcinoma, Squamous Cell
CASP8 (rs3834129) and CASP3 (rs4647601) polymorphisms in oropharynx cancer risk, tumor cell differentiation, and prognosis in a cohort of the Brazilian population.
Carcinoma, Squamous Cell
CASP9 c.-1339A>G and CASP3 c.-1191A>G polymorphisms alter susceptibility and clinical aspects of head and neck squamous cell carcinoma.
Carcinoma, Squamous Cell
Caspase-3 expression in tumorigenesis and prognosis of buccal mucosa squamous cell carcinoma.
Carcinoma, Squamous Cell
Caspase-3 expression is reduced, in the absence of cleavage, in terminally differentiated normal oral epithelium but is increased in oral squamous cell carcinomas and correlates with tumour stage.
Carcinoma, Squamous Cell
Combination of S-allylcysteine and lycopene induces apoptosis by modulating Bcl-2, Bax, Bim and caspases during experimental gastric carcinogenesis.
Carcinoma, Squamous Cell
Curcumin inhibits UV irradiation-induced oxidative stress and apoptotic biochemical changes in human epidermoid carcinoma A431 cells.
Carcinoma, Squamous Cell
Cytoplasmic and nuclear maspin expression in lung carcinomas: an immunohistochemical study using tissue microarrays.
Carcinoma, Squamous Cell
Detection of apoptosis and expression of apoptosis-associated proteins as early predictors of prognosis after irradiation therapy in stage IIIb uterine cervical cancer.
Carcinoma, Squamous Cell
Effect of photodynamic therapy on expression of HRAS, NRAS and caspase 3 genes at mRNA levels, apoptosis of head and neck squamous cell carcinoma cell line.
Carcinoma, Squamous Cell
Effect of protein kinase C alpha, caspase-3, and survivin on apoptosis of oral cancer cells induced by staurosporine.
Carcinoma, Squamous Cell
Enhanced apoptosis of squamous cell carcinoma cells by interleukin-2-activated cytotoxic lymphocytes combined with radiation and anticancer drugs.
Carcinoma, Squamous Cell
Ethanolic neem (Azadirachta indica) leaf extract induces apoptosis in the hamster buccal pouch carcinogenesis model by modulation of Bcl-2, Bim, caspase 8 and caspase 3.
Carcinoma, Squamous Cell
Evaluation of caspase-3 and caspase-8 deregulation in tongue squamous cell carcinoma, based on immunohistochemistry and computerised image analysis.
Carcinoma, Squamous Cell
Expression levels of cleaved caspase-3 and caspase-3 in tumorigenesis and prognosis of oral tongue squamous cell carcinoma.
Carcinoma, Squamous Cell
Expression of apoptotic and cell proliferation regulatory proteins in keratoacanthomas and squamous cell carcinomas of the skin.
Carcinoma, Squamous Cell
Expression of peripheral benzodiazepine receptor, PCNA, and caspase-3 in cells of skin melanoma and squamous cell carcinoma.
Carcinoma, Squamous Cell
Expression of the pro-apoptotic caspase 3/CPP32 in cutaneous basal and squamous cell carcinomas.
Carcinoma, Squamous Cell
FAS and FASL variations in outcomes of tobacco- and alcohol-related head and neck squamous cell carcinoma patients.
Carcinoma, Squamous Cell
Fumonisin B1 Inhibits Endoplasmic Reticulum Stress Associated-apoptosis After FoscanPDT Combined with C6-Pyridinium Ceramide or Fenretinide.
Carcinoma, Squamous Cell
Grape seed proanthocyanidins promote apoptosis in human epidermoid carcinoma A431 cells through alterations in Cdki-Cdk-cyclin cascade, and caspase-3 activation via loss of mitochondrial membrane potential.
Carcinoma, Squamous Cell
Increased killing of SCCVII squamous cell carcinoma cells after the combination of Pc 4 photodynamic therapy and dasatinib is associated with enhanced caspase-3 activity and ceramide synthase 1 upregulation.
Carcinoma, Squamous Cell
Induction of apoptosis and antiproliferative activity of naringenin in human epidermoid carcinoma cell through ROS generation and cell cycle arrest.
Carcinoma, Squamous Cell
Influence of CASP9 c.-1339A>G and CASP3 c.-1191A>G variants in outcome of patients with head and neck squamous cell carcinoma.
Carcinoma, Squamous Cell
Inverse correlation of apoptotic and angiogenic markers in squamous cell carcinoma of the head and neck.
Carcinoma, Squamous Cell
Let-7a microRNA suppresses therapeutics-induced cancer cell death by targeting caspase-3.
Carcinoma, Squamous Cell
Livin and caspase-3 expression are negatively correlated in cervical squamous cell cancer.
Carcinoma, Squamous Cell
Longitudinal bioluminescence imaging of the dynamics of Doxorubicin induced apoptosis.
Carcinoma, Squamous Cell
Modulating effect of hesperetin on the molecular expression pattern of apoptotic and cell proliferative markers in 7,12-dimethylbenz(a)anthracene-induced oral carcinogenesis.
Carcinoma, Squamous Cell
PARP1 and CASP3 gene expression in a patient with multiple head and neck squamous cell carcinoma and Parkinson disease.
Carcinoma, Squamous Cell
Prognostic value of apoptotic markers in squamous cell carcinoma of the urinary bladder.
Carcinoma, Squamous Cell
Proliferation, angiogenesis and apoptosis-associated proteins are molecular targets for chemoprevention of MNNG-induced gastric carcinogenesis by ethanolic Ocimum sanctum leaf extract.
Carcinoma, Squamous Cell
Resistance to apoptosis of HPV 16-infected laryngeal cancer cells is associated with decreased Bak and increased Bcl-2 expression.
Carcinoma, Squamous Cell
Resveratrol enhances the effects of ALA-PDT on skin squamous cells A431 through p38/ MAPK signaling pathway.
Carcinoma, Squamous Cell
Screening the pathogenic genes and pathways related to DMBA (7,12-dimethylbenz[a]anthracene)-induced transformation of hamster oral mucosa from precancerous lesions to squamous cell carcinoma.
Carcinoma, Squamous Cell
Study of the extraction process and in vivo inhibitory effect of ganoderma triterpenes in oral mucosa cancer.
Carcinoma, Squamous Cell
Surgical removal of the parametrial fat pads stimulates apoptosis and inhibits UVB-induced carcinogenesis in mice fed a high-fat diet.
Carcinoma, Squamous Cell
The sensitivity of head and neck carcinoma cells to statins is related to the expression of their Ras expression status, and statin-induced apoptosis is mediated via suppression of the Ras/ERK and Ras/mTOR pathways.
Carcinoma, Squamous Cell
Three apoptotic genes are upregulated in a patient with Alzheimer's disease and well-differentiated squamous cell carcinoma.
Carcinoma, Squamous Cell
Transfection of mutant p53 gene depresses X-ray- or CDDP-induced apoptosis in a human squamous cell carcinoma of the head and neck.
Carcinoma, Squamous Cell
Tumor-specific cytotoxic activity of 1,2,3,4-tetrahydroisoquinoline derivatives against human oral squamous cell carcinoma cell lines.
Carcinoma, Squamous Cell
Tyrosine-nitration of caspase 3 and cytochrome c does not suppress apoptosis induction in squamous cell carcinoma cells.
Carcinoma, Squamous Cell
Vanadate-induced antiproliferative and apoptotic response in esophageal squamous carcinoma cell line EC109.
Carcinoma, Squamous Cell
WITHDRAWN: Expression analysis of Sca-1 and its significance in lung cancers.
Carcinoma, Squamous Cell
Zinc Oxide Nanoparticle Induces Apoptosis in Human Epidermoid Carcinoma Cells Through Reactive Oxygen Species and DNA Degradation.
Carcinoma, Squamous Cell
[Apoptosis modulation by PMA occurs independently of TsPO expression in squamous cell carcinoma cells].
Carcinoma, Squamous Cell
[CD-34 and CASPASE-3 biomarkers expression in esophageal epidermoid carcinoma]
Carcinoma, Squamous Cell
[Effect of human trophoblast cell-surface antigen 2 gene expression by RNA interference on proliferation and apoptosis of tongue squamous cell carcinoma and its mechanism].
Carcinoma, Squamous Cell
[Expression of apoptosis and proliferation related genes in carcinogenesis of lung squamous cell carcinoma in rats]
Carcinoma, Squamous Cell
[Expression of Survivin mRNA and Caspase-3 mRNA and their correlation in tongue squamous cell carcinoma]
Carcinoma, Squamous Cell
[Microwave Hyperthermia Combined with Gemcitabine Inhibits Proliferation ?and Induces Apoptosis of Human Lung Squamous Carcinoma Cells].
Carcinoma, Squamous Cell
[Roles of cyclooxygenase-2 and caspase-3 expression in pathogenesis of lung carcinoma: an experiment with rats]
Carcinoma, Squamous Cell
[Study of apoptosis related factors regulatory mechanism of resveratrol to human skin squamous cell carcinoma A431 xenograft in nude mice].
Carcinoma, Squamous Cell
[The effect of tanshinone ?A potentiates the effects of Cisplatin in Fadu cells in vitro through downregulation of survivin].
Carcinoma, Squamous Cell
[The relationship between caspase-3 expression and cell proliferation in rat lung squamous cell carcinoma.]
Carcinoma, Transitional Cell
Inhibition of thromboxane synthase activity modulates bladder cancer cell responses to chemotherapeutic agents.
Carcinoma, Transitional Cell
Shikonin-induced apoptosis involves caspase-3 activity in a human bladder cancer cell line (T24).
Carcinoma, Transitional Cell
Silibinin causes cell cycle arrest and apoptosis in human bladder transitional cell carcinoma cells by regulating CDKI-CDK-cyclin cascade, and caspase 3 and PARP cleavages.
Carcinosarcoma
Immunohistochemical evaluation of bcl-2, ER-alpha, caspase -3, -8, -9, PCNA and Ki-67 expressions in canine mammary carcinomas.
Carcinosarcoma
Possible in vivo mechanisms involved in photodynamic therapy using tetrapyrrolic macrocycles.
Cardio-Renal Syndrome
Histopathological Changes in the Kidney following Congestive Heart Failure by Volume Overload in Rats.
Cardiomegaly
Dexrazoxane does not protect against doxorubicin-induced damage in young rats.
Cardiomegaly
Fatty acid-binding protein 4 silencing protects against lipopolysaccharide-induced cardiomyocyte hypertrophy and apoptosis by inhibiting the Toll-like receptor 4-nuclear factor-?B pathway.
Cardiomegaly
Histone deacetylase (HDAC) inhibition improves myocardial function and prevents cardiac remodeling in diabetic mice.
Cardiomegaly
Involvement of Endoplasmic Reticulum Stress-Mediated Activation of C/EBP Homologous Protein in Aortic Regurgitation-Induced Cardiac Remodeling in Mice.
Cardiomegaly
Reversion of left ventricle remodeling in spontaneously hypertensive rats by valsartan is associated with the inhibition of caspase-3, -8 and -9 activities.
Cardiomegaly
Stem cell antigen 1 protects against cardiac hypertrophy and fibrosis after pressure overload.
Cardiomegaly
The possible role of caspase-3 in pathological and physiological cardiac hypertrophy in rats.
Cardiomegaly
Treatment with hydrogen molecule attenuates cardiac dysfunction in streptozotocin-induced diabetic mice.
Cardiomyopathies
A novel compound DT-010 protects against doxorubicin-induced cardiotoxicity in zebrafish and H9c2 cells by inhibiting reactive oxygen species-mediated apoptotic and autophagic pathways.
Cardiomyopathies
A polyphenol-metal nanoparticle platform for tunable release of liraglutide to improve blood glycemic control and reduce cardiovascular complications in a mouse model of type II diabetes.
Cardiomyopathies
Anti-apoptotic potential of gymnemic acid phospholipid complex pretreatment in Wistar rats with experimental cardiomyopathy.
Cardiomyopathies
Apoptosis in heart failure: release of cytochrome c from mitochondria and activation of caspase-3 in human cardiomyopathy.
Cardiomyopathies
Characterization of a degenerative cardiomyopathy associated with domoic acid toxicity in California sea lions (Zalophus californianus).
Cardiomyopathies
Date Palm Pollen Extract Avert Doxorubicin-Induced Cardiomyopathy Fibrosis and Associated Oxidative/Nitrosative Stress, Inflammatory Cascade, and Apoptosis-Targeting Bax/Bcl-2 and Caspase-3 Signaling Pathways.
Cardiomyopathies
Doxorubicin induces apoptosis by activation of caspase-3 in cultured cardiomyocytes in vitro and rat cardiac ventricles in vivo.
Cardiomyopathies
Emerging protective roles of shengmai injection in septic cardiomyopathy in mice by inducing myocardial mitochondrial autophagy via caspase-3/Beclin-1 axis.
Cardiomyopathies
Endurance exercise training suppresses Parkinson disease-induced overexpression of apoptotic mediators in the heart.
Cardiomyopathy, Alcoholic
Deficiency of insulin-like growth factor 1 reduces vulnerability to chronic alcohol intake-induced cardiomyocyte mechanical dysfunction: Role of AMPK.
Cardiomyopathy, Dilated
Altered interleukin-1 receptor antagonist and interleukin-18 mRNA expression in myocardial tissues of patients with dilatated cardiomyopathy.
Cardiomyopathy, Dilated
[Effects of Mongolian new medicine-? on cardiac functions, endoplasmic reticulum stress and apoptosis in congestive heart failure rats with dilated cardiomyopathy].
Cardiotoxicity
68Ga-Galmydar: A PET imaging tracer for noninvasive detection of Doxorubicin-induced cardiotoxicity.
Cardiotoxicity
?-asarone induces cardiac defects and QT prolongation through mitochondrial apoptosis pathway in zebrafish.
Cardiotoxicity
Activated ROCK/Akt/eNOS and ET-1/ERK pathways in 5-fluorouracil-induced cardiotoxicity: modulation by simvastatin.
Cardiotoxicity
All-trans-retinoic acid ameliorates doxorubicin-induced cardiotoxicity: in vivo potential involvement of oxidative stress, inflammation, and apoptosis via caspase-3 and p53 down-expression.
Cardiotoxicity
Anti-apoptotic potential of gymnemic acid phospholipid complex pretreatment in Wistar rats with experimental cardiomyopathy.
Cardiotoxicity
Apremilast reversed carfilzomib-induced cardiotoxicity through inhibition of oxidative stress, NF-?B and MAPK signaling in rats.
Cardiotoxicity
Arsenic trioxide-induced apoptosis in H9c2 cardiomyocytes: implications in cardiotoxicity.
Cardiotoxicity
Autophagy plays an important role in sunitinib-mediated cell death in H9c2 cardiac muscle cells.
Cardiotoxicity
Beneficial effects of carbon monoxide-releasing molecule-2 (CORM-2) on acute doxorubicin cardiotoxicity in mice: Role of oxidative stress and apoptosis.
Cardiotoxicity
Benidipine prevents oxidative stress, inflammatory changes and apoptosis related myofibril damage in isoproterenol-induced myocardial infarction in rats.
Cardiotoxicity
Cardioprotective and cardiotoxic effects of quercetin and two of its in vivo metabolites on differentiated h9c2 cardiomyocytes.
Cardiotoxicity
Cardioprotective Effects of Hesperetin against Doxorubicin-Induced Oxidative Stress and DNA Damage in Rat.
Cardiotoxicity
Cardioprotective effects of nicorandil, a mitochondrial potassium channel opener against doxorubicin-induced cardiotoxicity in rats.
Cardiotoxicity
Chemoprotective role of an extract of the heart of the Phoenix dactylifera tree on adriamycin-induced cardiotoxicity and nephrotoxicity by regulating apoptosis, oxidative stress and PD-1 suppression.
Cardiotoxicity
Clozapine-induced cardiotoxicity in rats: Involvement of tumour necrosis factor alpha, NF-?? and caspase-3.
Cardiotoxicity
Dose-Dependent Cardioprotective Effect of Hemin in Doxorubicin-Induced Cardiotoxicity Via Nrf-2/HO-1 and TLR-5/NF-?B/TNF-? Signaling Pathways.
Cardiotoxicity
Fisetin, a plant flavonoid ameliorates doxorubicin-induced cardiotoxicity in experimental rats: the decisive role of caspase-3, COX-II, cTn-I, iNOs and TNF-?.
Cardiotoxicity
Gingko Biloba protects cardiomyocytes against acute doxorubicin induced cardiotoxicity by suppressing oxidative stress.
Cardiotoxicity
In Vivo Protective Effects of Diosgenin against Doxorubicin-Induced Cardiotoxicity.
Cardiotoxicity
Interaction of the HMG-CoA reductase inhibitor lovastatin and nitric oxide in cardiomyocyte cell death.
Cardiotoxicity
Lovastatin-induced cardiac toxicity involves both oncotic and apoptotic cell death with the apoptotic component blunted by both caspase-2 and caspase-3 inhibitors.
Cardiotoxicity
Low-Dose Radiation Enhanced Inhibition of Breast Tumor Xenograft and Reduced Myocardial Injury Induced by Doxorubicin.
Cardiotoxicity
Metformin and/or low dose radiation reduces cardiotoxicity and apoptosis induced by cyclophosphamide through SIRT-1/SOD and BAX/Bcl-2 pathways in rats.
Cardiotoxicity
Modulatory effects of curcumin on redox status, mitochondrial function, and caspace-3 expression during atrazin-induced toxicity.
Cardiotoxicity
Noninvasive molecular imaging of apoptosis in a mouse model of anthracycline-induced cardiotoxicity.
Cardiotoxicity
Paeonol Attenuates Methotrexate-Induced Cardiac Toxicity in Rats by Inhibiting Oxidative Stress and Suppressing TLR4-Induced NF-?B Inflammatory Pathway.
Cardiotoxicity
Protective Effects of Carvedilol and Vitamin C against Azithromycin-Induced Cardiotoxicity in Rats via Decreasing ROS, IL1-?, and TNF-? Production and Inhibiting NF-?B and Caspase-3 Expression.
Cardiotoxicity
Role of ATP-Sensitive Potassium Channel (KATP) and eNOS in Mediating the Protective Effect of Nicorandil in Cyclophosphamide-Induced Cardiotoxicity.
Cardiotoxicity
Targeting MDR-1 gene expression, BAX/BCL2, caspase-3, and Ki-67 by nanoencapsulated imatinib and hesperidin to enhance anticancer activity and ameliorate cardiotoxicity.
Cardiotoxicity
The IL-6/STAT Signaling Pathway and PPAR? Are Involved in Mediating the Dose-Dependent Cardioprotective Effects of Fenofibrate in 5-Fluorouracil-Induced Cardiotoxicity.
Cardiovascular Diseases
Caspase inhibitors: a review of recently patented compounds (2013-2015).
Cardiovascular Diseases
Diabetes triggers a PARP1 mediated death pathway in the heart through participation of FoxO1.
Cardiovascular Diseases
Selective detection and inhibition of active caspase-3 in cells with optimized peptides.
Cardiovascular Diseases
Telmisartan inhibits methylglyoxal-mediated cell death in human vascular endothelium.
Cardiovascular Diseases
The clinical impact of circulating caspase-3 p17 level: a potential new biomarker for myocardial injury and cardiovascular disease.
caspase-3 deficiency
Aggressive fibromatosis (desmoid tumor) is derived from mesenchymal progenitor cells.
caspase-3 deficiency
Amyloid beta-induced neuronal death is bax-dependent but caspase-independent.
caspase-3 deficiency
Cardiac dysfunction and impaired compensatory response to pressure overload in mice deficient in stem cell antigen-1.
caspase-3 deficiency
Caspase 3 deficiency rescues peripheral nervous system defect in retinoblastoma nullizygous mice.
caspase-3 deficiency
Caspase-3 deficiency during development increases vulnerability to hypoxic-ischemic injury through caspase-3-independent pathways.
caspase-3 deficiency
Caspase-3 deficiency results in disrupted synaptic homeostasis and impaired attention control.
caspase-3 deficiency
Caspase-3 deficiency reveals a physiologic role for Smac/DIABLO in regulating programmed cell death.
caspase-3 deficiency
Caspase-3 gene knockout defines cell lineage specificity for programmed cell death signaling in the ovary.
caspase-3 deficiency
Caspase-3 suppresses diethylnitrosamine-induced hepatocyte death, compensatory proliferation and hepatocarcinogenesis through inhibiting p38 activation.
caspase-3 deficiency
Caspase-3-deficiency induces hyperplasia of supporting cells and degeneration of sensory cells resulting in the hearing loss.
caspase-3 deficiency
Cell-in-Cell Death Is Not Restricted by Caspase-3 Deficiency in MCF-7 Cells.
caspase-3 deficiency
Decreased apoptosis in proliferative and postmitotic regions of the Caspase 3-deficient embryonic central nervous system.
caspase-3 deficiency
Deficiency of caspase-3 in MCF7 cells blocks Bax-mediated nuclear fragmentation but not cell death.
caspase-3 deficiency
E2F1 mediates death of B-amyloid-treated cortical neurons in a manner independent of p53 and dependent on Bax and caspase 3.
caspase-3 deficiency
Epistatic and independent functions of caspase-3 and Bcl-X(L) in developmental programmed cell death.
caspase-3 deficiency
Extensive apoptosis and abnormal morphogenesis in pro-caspase-3 transgenic zebrafish during development.
caspase-3 deficiency
Irofulven induces apoptosis in breast cancer cells regardless of caspase-3 status.
caspase-3 deficiency
Lack of caspase-3 attenuates immobilization-induced muscle atrophy and loss of tension generation along with mitigation of apoptosis and inflammation.
caspase-3 deficiency
Reconstitution of caspase 3 sensitizes MCF-7 breast cancer cells to doxorubicin- and etoposide-induced apoptosis.
caspase-3 deficiency
Reconstitution of caspase-3 sensitizes MCF-7 breast cancer cells to radiation therapy.
caspase-3 deficiency
Rotundic acid induces Cas3-MCF-7 cell apoptosis through the p53 pathway.
caspase-3 deficiency
Simultaneous deletion of p21Cip1/Waf1 and caspase-3 accelerates proliferation and partially rescues the differentiation defects of caspase-3 deficient hematopoietic stem cells.
caspase-3 deficiency
Stem cell antigen 1 protects against cardiac hypertrophy and fibrosis after pressure overload.
caspase-3 deficiency
Strain-dependent neurodevelopmental abnormalities in caspase-3-deficient mice.
caspase-6 deficiency
Efficient apoptosis requires feedback amplification of upstream apoptotic signals by effector caspase-3 or -7.
caspase-9 deficiency
Interplay between Caspase 9 and X-linked Inhibitor of Apoptosis Protein (XIAP) in the oocyte elimination during fetal mouse development.
Cataract
Activation of Sirtuin1 by lyceum barbarum polysaccharides in protection against diabetic cataract.
Cataract
Apoptosis Factors of Lens Epithelial Cells Responsible for Cataractogenesis in Vitrectomized Eyes with Silicone Oil Tamponade.
Cataract
Caspase-3 and its inhibitor Ac-DEVD-CHO in rat lens epithelial cell apoptosis induced by hydrogen in vitro.
Cataract
Decreased caspase-3 activity in human lens epithelium from posterior subcapsular cataracts.
Cataract
Effects of ELL-associated factor 2 on ultraviolet radiation-induced cataract formation in mice.
Cataract
Genome-wide analysis of methylation in giant pandas with cataract by methylation-dependent restriction-site associated DNA sequencing (MethylRAD).
Cataract
Kinetics of GADD45?, TP53 and CASP3 gene expression in the rat lens in vivo in response to exposure to double threshold dose of UV-B radiation.
Cataract
Localization of cell apoptosis in the opaque portion of anterior polar cataract and anterior capsulotomy margin.
Cataract
Parthenolide protects human lens epithelial cells from oxidative stress-induced apoptosis via inhibition of activation of caspase-3 and caspase-9.
Cataract
Protective effect of resveratrol on lens epithelial cell apoptosis in diabetic cataract rat.
Cataract
Role of the intrinsic apoptotic pathway in cataractogenesis in type 2 diabetic patients.
Cataract
TUG1 promotes lens epithelial cell apoptosis by regulating miR-421/caspase-3 axis in age-related cataract.
Cataract
[Expression of thioredoxin-2 in human lens epithelial cells with oxidative damage and its significance].
Celiac Disease
Mechanism of villous atrophy in celiac disease: role of apoptosis and epithelial regeneration.
Central Nervous System Infections
Caspase-3 activation is required for reovirus-induced encephalitis in vivo.
Cerebral Hemorrhage
704 Induction of DNA Fragmentation and Caspase-3 Cleavage after Experimental Intracerebral Hemorrhage.
Cerebral Hemorrhage
High Serum Levels of Caspase-3 and Early Mortality in Patients with Severe Spontaneous Intracerebral Hemorrhage.
Cerebral Hemorrhage
Low-density lipoprotein receptor-related protein-1 facilitates heme scavenging after intracerebral hemorrhage in mice.
Cerebral Hemorrhage
Significant elevation of serum caspase-3 levels in patients with intracerebral hemorrhage.
Cerebral Hemorrhage
The Crucial Role of Cyclin-Dependent Kinase-5-Ataxia-Telangiectasia Mutated Axis in ICH-Induced Neuronal Injury of Rat Model.
Cerebral Hemorrhage
The impact of neuronal Notch-1/JNK pathway on intracerebral hemorrhage-induced neuronal injury of rat model.
Cerebral Hemorrhage
[Effect of manual acupuncture of "Shuigou" (GV26)"Neiguan" (PC6) on neurological function and expression of apoptosis-related factors in brain tissues surrounding hematoma in intracerebral hemorrhage rats].
Cerebral Hemorrhage
[Effects of Xijiao Dihuang decoction on the expressions of bcl-2, caspase-3, TNF-alpha and IL-6 after acute intracerebral hemorrhage in rats]
Cerebral Infarction
Angelica sinensis Exerts Angiogenic and Anti-apoptotic Effects Against Cerebral Ischemia-Reperfusion Injury by Activating p38MAPK/HIF-1[Formula: see text]/VEGF-A Signaling in Rats.
Cerebral Infarction
Caspase-3 inhibitor prevents the apoptosis of brain tissue in rats with acute cerebral infarction.
Cerebral Infarction
CX3CL1 is neuroprotective in permanent focal cerebral ischemia in rodents.
Cerebral Infarction
Delayed administration of parecoxib, a specific COX-2 inhibitor, attenuated postischemic neuronal apoptosis by phosphorylation Akt and GSK-3?.
Cerebral Infarction
Electro-acupuncture combined with transcranial magnetic stimulation improves learning and memory function of rats with cerebral infarction by inhibiting neuron cell apoptosis.
Cerebral Infarction
Facilitation of ultrasonic microvesicles on homing and molecular mechanism of bone marrow mesenchymal stem cells in cerebral infarction patients.
Cerebral Infarction
Ferulic Acid Administered at Various Time Points Protects against Cerebral Infarction by Activating p38 MAPK/p90RSK/CREB/Bcl-2 Anti-Apoptotic Signaling in the Subacute Phase of Cerebral Ischemia-Reperfusion Injury in Rats.
Cerebral Infarction
Genetic inhibition of caspase-2 reduces hypoxic-ischemic and excitotoxic neonatal brain injury.
Cerebral Infarction
Granulocyte colony-stimulating factor and stromal cell-derived factor-1 combination therapy: A more effective treatment for cerebral ischemic stroke.
Cerebral Infarction
Histogranin reduced brain injury after transient focal ischemia in rats.
Cerebral Infarction
Mild hypothermia combined with neural stem cell transplantation for hypoxic-ischemic encephalopathy: neuroprotective effects of combined therapy.
Cerebral Infarction
miR-128b Promotes Cerebral Infarction by Regulating the Expressions of BCL-2 and CAPASE3.
Cerebral Infarction
miR-130a alleviates neuronal apoptosis and changes in expression of Bcl-2/Bax and caspase-3 in cerebral infarction rats through PTEN/PI3K/Akt signaling pathway.
Cerebral Infarction
miR-24 reduces serum lipid levels and inhibits brain tissue cells apoptosis of rats with cerebral infarction.
Cerebral Infarction
miR-24 Reduces Serum Lipid Levels and Inhibits Brain Tissue Cells Apoptosis of Rats with Cerebral Infarction.
Cerebral Infarction
Multimodal Neuroprotection Induced by PACAP38 in Oxygen-Glucose Deprivation and Middle Cerebral Artery Occlusion Stroke Models.
Cerebral Infarction
Neuroprotection by triptolide against cerebral ischemia/reperfusion injury through the inhibition of NF-?B/PUMA signal in rats.
Cerebral Infarction
Neuroprotective effects of Bcl-2 overexpression on nerve cells of rats with acute cerebral infarction.
Cerebral Infarction
Neuroprotective Effects of Danshen Chuanxiongqin Injection Against Ischemic Stroke: Metabolomic Insights by UHPLC-Q-Orbitrap HRMS Analysis.
Cerebral Infarction
Neuroprotective effects of different frequency preconditioning exercise on neuronal apoptosis after focal brain ischemia in rats.
Cerebral Infarction
Passive Movement Improves the Learning and Memory Function of Rats with Cerebral Infarction by Inhibiting Neuron Cell Apoptosis.
Cerebral Infarction
Peroxisome proliferator-activated receptor delta regulation of miR-15a in ischemia-induced cerebral vascular endothelial injury.
Cerebral Infarction
Picroside II Exerts a Neuroprotective Effect by Inhibiting the Mitochondria Cytochrome C Signal Pathway Following Ischemia Reperfusion Injury in Rats.
Cerebral Infarction
Rehabilitation training inhibits neuronal apoptosis by down-regulation of TLR4/MyD88 signaling pathway in mice with cerebral ischemic stroke.
Cerebral Infarction
Role of JNK Signaling Pathway in Dexmedetomidine Post-Conditioning-Induced Reduction of the Inflammatory Response and Autophagy Effect of Focal Cerebral Ischemia Reperfusion Injury in Rats.
Cerebral Infarction
Sevoflurane Preconditioning against Focal Cerebral Ischemia: Inhibition of Apoptosis in the Face of Transient Improvement of Neurological Outcome.
Cerebral Infarction
Sevoflurane reduces ischemic brain injury in rats with diet and streptozotocin-induced diabetes.
Cerebral Infarction
Silencing the gene encoding C/EBP homologous protein lessens acute brain injury following ischemia/reperfusion.
Cerebral Infarction
SO2 inhalation contributes to the development and progression of ischemic stroke in the brain.
Cerebral Infarction
The protective role of verbenalin in rat model of focal cerebral ischemia reperfusion.
Cerebral Infarction
The Synergistic Neuroprotective Effects of Combined Rosuvastatin and Resveratrol Pretreatment against Cerebral Ischemia/Reperfusion Injury.
Cerebral Infarction
Transplantation of bone marrow-derived endothelial progenitor cells attenuates cerebral ischemia and reperfusion injury by inhibiting neuronal apoptosis, oxidative stress and nuclear factor-?B expression.
Cerebral Infarction
Trefoil factor 3 as an endocrine neuroprotective factor from the liver in experimental cerebral ischemia/reperfusion injury.
Cerebral Infarction
Upregulated microRNA-31 inhibits oxidative stress-induced neuronal injury through the JAK/STAT3 pathway by binding to PKD1 in mice with ischemic stroke.
Cerebral Infarction
[Effect on p53 and caspase-3 of hippocampal neuron in the rats with cerebral ischemia-reperfusion injury treated with electroacupuncture preconditioning at the acupoints on the basis of biao and ben relationship].
Cerebral Infarction
[Effects of Carthamus tinctorius injection on bcl-2, caspase-3 expression related to neurons apoptosis after local cerebral ischemia]
Cerebral Infarction
[Effects of Tongnao Huoluo acupuncture therapy on Caspase-3 and Bcl-2 of rats with acute cerebral infarction].
Cerebral Infarction
[IMMP2L gene mutation activates mitochondrial apoptotic pathway to aggravate cerebral ischemic injury in mice].
Cerebral Infarction
[Preliminary study on substitution of Antelope Horn in Danqi Piantan capsule with artificial bezoar].
Cerebral Infarction
[Protective effects of P2X7 receptor inhibition in cerebral ischemia/reperfusion injury in rats].
Cerebrovascular Disorders
Toxicity of substrate-bound amyloid peptides on vascular smooth muscle cells is enhanced by homocysteine.
Cervical Intraepithelial Neoplasia
Expression of survivin, cyclinD1, p21(WAF1), caspase-3 in cervical cancer and its relation with prognosis.
Cervical Intraepithelial Neoplasia
Immunohistochemical study of NF-?B p65, c-IAP2 and caspase-3 expression in cervical cancer.
Cervical Intraepithelial Neoplasia
LC3B upregulation by NANOG promotes immune resistance and stem-like property through hyperactivation of EGFR signaling in immune-refractory tumor cells.
Chagas Disease
Characterization of CD4(+) Cytotoxic Lymphocytes and Apoptosis Markers Induced by Trypanossoma cruzi Infection.
Chagas Disease
Expression of ki-67 antigen and caspase-3 protein in benign lesions and esophageal carcinoma.
Chagas Disease
Identification of phenotypic markers of B cells from patients with Chagas disease.
Chemical and Drug Induced Liver Injury
Caspase 3 role and immunohistochemical expression in assessment of apoptosis as a feature of H1N1 vaccine-caused Drug-Induced Liver Injury (DILI).
Cholangiocarcinoma
A Ligand for Peroxisome Proliferator-Activated Receptor gamma Inhibits Human Cholangiocarcinoma Cell Growth: Potential Molecular Targeting Strategy for Cholangioma.
Cholangiocarcinoma
Apoptosis of Human Cholangiocarcinoma Cell Lines induced by ?-Escin through Mitochondrial Caspase-dependent Pathway.
Cholangiocarcinoma
Cyclooxygenase-2 and ERBB-2 in cholangiocarcinoma: potential therapeutic targets.
Cholangiocarcinoma
Metformin potentiates the anticancer activities of gemcitabine and cisplatin against cholangiocarcinoma cells in vitro and in vivo.
Cholangiocarcinoma
miR-373 inhibits autophagy and further promotes apoptosis of cholangiocarcinoma cells by targeting ULK1.
Cholangiocarcinoma
Pro-survival Role of Heat Shock Factor 1 (HSF1) in the Pathogenesis of PancreatoBiliary Tumors.
Cholangiocarcinoma
Synergistic cytotoxicity and apoptosis induced in human cholangiocarcinoma cell lines by a combined treatment with tumor necrosis factor-alpha (TNF-alpha) and triptolide.
Cholangiocarcinoma
Tamoxifen enhances therapeutic effects of gemcitabine on cholangiocarcinoma tumorigenesis.
Cholangiocarcinoma
Thalidomide attenuates tumor growth and preserves fast-twitch skeletal muscle fibers in cholangiocarcinoma rats.
Cholangiocarcinoma
TNF-alpha induces caspase 3 (CPP 32) dependent apoptosis in human cholangiocarcinoma cell line.
Cholangitis
Inactivation of caspase 8 in liver parenchymal cells confers protection against murine obstructive cholestasis.
Cholestasis, Intrahepatic
Li-Dan-He-Ji Improves Infantile Cholestasis Hepatopathy Through Inhibiting Calcium-Sensing Receptor-Mediated Hepatocyte Apoptosis.
Cholesteatoma
Analysis of histopathological aspects and bone destruction characteristics in acquired middle ear cholesteatoma of pediatric and adult patients.
Cholesteatoma
Caspase-3, caspase-8, and nuclear factor-kappaB expression in human cholesteatoma.
Cholesteatoma
Cholesteatoma epithelium is characterized by increased expression of Ki-67, p53 and p21, with minimal apoptosis.
Chondrosarcoma
(-)-Epigallocatechin-3-gallate induces apoptosis and suppresses proliferation by inhibiting the human Indian Hedgehog pathway in human chondrosarcoma cells.
Chondrosarcoma
Anti-chondrosarcoma effects of PEDF mediated via molecules important to apoptosis, cell cycling, adhesion and invasion.
Chondrosarcoma
BL-038, a Benzofuran Derivative, Induces Cell Apoptosis in Human Chondrosarcoma Cells through Reactive Oxygen Species/Mitochondrial Dysfunction and the Caspases Dependent Pathway.
Chondrosarcoma
Combination BET Family Protein and HDAC Inhibition Synergistically Elicits Chondrosarcoma Cell Apoptosis Through RAD51-Related DNA Damage Repair.
Chondrosarcoma
Induction of sirtuin-1 signaling by resveratrol induces human chondrosarcoma cell apoptosis and exhibits antitumor activity.
Chondrosarcoma
Involvement of caspase-3 in epigallocatechin-3-gallate-mediated apoptosis of human chondrosarcoma cells.
Chondrosarcoma
MLN4924, a Protein Neddylation Inhibitor, Suppresses the Growth of Human Chondrosarcoma through Inhibiting Cell Proliferation and Inducing Endoplasmic Reticulum Stress-Related Apoptosis.
Chondrosarcoma
Recombinant human PDCD5 sensitizes chondrosarcomas to cisplatin chemotherapy in vitro and in vivo.
Chondrosarcoma
SGTB Promotes the Caspase-Dependent Apoptosis in Chondrocytes of Osteoarthritis.
Chondrosarcoma
Trichodermin induces cell apoptosis through mitochondrial dysfunction and endoplasmic reticulum stress in human chondrosarcoma cells.
Chondrosarcoma
Vacuolar Protein Sorting 4B (VPS4B) Regulates Apoptosis of Chondrocytes via p38 Mitogen-Activated Protein Kinases (MAPK) in Osteoarthritis.
Chordoma
Histone deacetylase inhibitors as potential therapeutic approaches for chordoma: An immunohistochemical and functional analysis.
Chordoma
Upregulation Of miR-149-3p Suppresses Spinal Chordoma Malignancy By Targeting Smad3.
Chorioamnionitis
ADRB3 adrenergic receptor is a key regulator of human myometrial apoptosis and inflammation during chorioamnionitis.
Choriocarcinoma
Long Noncoding RNA LINC00261 Suppresses Cell Proliferation and Invasion and Promotes Cell Apoptosis in Human Choriocarcinoma.
Choriocarcinoma
Trichomislin, a novel ribosome-inactivating protein, induces apoptosis that involves mitochondria and caspase-3.
Chronic Periodontitis
Expression of key executioner of apoptosis caspase-3 in periodontal health and disease.
Chronic Periodontitis
Porphyromonas gingivalis Differentially Modulates Apoptosome Apoptotic Peptidase Activating Factor 1 in Epithelial Cells and Fibroblasts.
Coinfection
Adeno-associated virus type 2 induces apoptosis in human papillomavirus-infected cell lines but not in normal keratinocytes.
Coinfection
Adenovirus-mediated transfer of caspase-3 with Fas ligand induces drastic apoptosis in U-373MG glioma cells.
Colitis
A fusion protein composed of IL-2 and caspase-3 ameliorates the outcome of experimental inflammatory colitis.
Colitis
Acrylamide exposure aggravates the development of ulcerative colitis in mice through activation of NF-?B, inflammatory cytokines, iNOS, and oxidative stress.
Colitis
Ameliorative effects of bombesin and neurotensin on trinitrobenzene sulphonic acid-induced colitis, oxidative damage and apoptosis in rats.
Colitis
Arsenic trioxide reduces 2,4,6-trinitrobenzene sulfonic acid-induced murine colitis via nuclear factor-{kappa}B down-regulation and caspase-3 activation.
Colitis
Chromosome region maintenance-1 (CRM1) regulates apoptosis of intestinal epithelial cells via p27kip1 in Crohn's disease.
Colitis
Cord Blood CD8+ T Cells Have a Natural Propensity to Express IL-4?in a Fatty Acid Metabolism and Caspase Activation-Dependent Manner.
Colitis
Decreased expression of MUC2 due to a decrease in the expression of lectins and apoptotic defects in colitis patients.
Colitis
Detection of apoptoses in gastro-intestinal graft-versus-host disease and cytomegalovirus colitis by a commercially available antibody against caspase-3.
Colitis
Effects of Dietary Oat Beta-Glucans on Colon Apoptosis and Autophagy through TLRs and Dectin-1 Signaling Pathways-Crohn's Disease Model Study.
Colitis
Effects of humanin on experimental colitis induced by 2,4,6-trinitrobenzene sulphonic acid in rats.
Colitis
Epithelial-specific ETS-1 (ESE1/ELF3) regulates apoptosis of intestinal epithelial cells in ulcerative colitis via accelerating NF-?B activation.
Colitis
Extracellular Vesicles Derived from Bone Marrow Mesenchymal Stem Cells Protect against Experimental Colitis via Attenuating Colon Inflammation, Oxidative Stress and Apoptosis.
Colitis
Immunohistochemical examination of anti-inflammatory and anti-apoptotic effects of hesperetin on trinitrobenzene sulfonic acid induced colitis in rats.
Colitis
Knockdown of ghrelin-O-acyltransferase attenuates colitis through the modulation of inflammatory factors and tight junction proteins in the intestinal epithelium.
Colitis
Le Carbone, a charcoal supplement, modulates DSS-induced acute colitis in mice through activation of AMPK? and downregulation of STAT3 and caspase 3 dependent apoptotic pathways.
Colitis
Melatonin reduces bacterial translocation and apoptosis in trinitrobenzene sulphonic acid-induced colitis of rats.
Colitis
Neutrophil apoptosis is delayed in an equine model of colitis: Implications for the development of SIRS.
Colitis
PGI2 Inhibits Intestinal Epithelial Permeability and Apoptosis to Alleviate Colitis.
Colitis
Polydatin ameliorates dextran sulfate sodium-induced colitis by decreasing oxidative stress and apoptosis partially via Sonic hedgehog signaling pathway.
Colitis
Runt-related transcription factor 2 (RUNX2) inhibits apoptosis of intestinal epithelial cells in Crohn's disease.
Colitis
Sam68 modulates apoptosis of intestinal epithelial cells via mediating NF-?B activation in ulcerative colitis.
Colitis
Si Shen Wan Inhibits mRNA Expression of Apoptosis-Related Molecules in p38 MAPK Signal Pathway in Mice with Colitis.
Colitis
Targeted therapy to the IL-2R using diphtheria toxin and caspase-3 fusion proteins modulates Treg and ameliorates inflammatory colitis.
Colitis
Targeting sphingosine kinase 1 (SphK1) and apoptosis by colon-specific delivery formula of resveratrol in treatment of experimental ulcerative colitis in rats.
Colitis
Tauroursodeoxycholic acid inhibits experimental colitis by preventing early intestinal epithelial cell death.
Colitis
The acetylome regulators Hdac1 and Hdac2 differently modulate intestinal epithelial cell dependent homeostatic responses in experimental colitis.
Colitis
The effect of heme oxygenase-1 induction by glutamine on TNBS-induced colitis. The effect of glutamine on TNBS colitis.
Colitis
Treatment with Mesna and n-3 polyunsaturated fatty acids ameliorates experimental ulcerative colitis in rats.
Colitis
Vacuolar protein sorting 4B regulates apoptosis of intestinal epithelial cells via p38 MAPK in Crohn's disease.
Colitis, Ulcerative
Gliclazide attenuates acetic acid-induced colitis via the modulation of PPAR?, NF-?B and MAPK signaling pathways.
Colitis, Ulcerative
Imbalance of Controlled Death in Peripheral Blood Lymphocytes in Crohn's Disease and Ulcerative Colitis.
Colitis, Ulcerative
Inflammation-induced Occludin Downregulation Limits Epithelial Apoptosis by Suppressing Caspase 3 Expression.
Colitis, Ulcerative
Visilizumab induces apoptosis of mucosal T lymphocytes in ulcerative colitis through activation of caspase 3 and 8 dependent pathways.
Colitis-Associated Neoplasms
Activation of AMPK by chitosan oligosaccharide in intestinal epithelial cells: Mechanism of action and potential applications in intestinal disorders.
Colonic Neoplasms
3,5-bis(Benzylidene)-1-[3-(2-hydroxyethylthio)propanoyl]-piperidin-4-ones:A novel cluster of potent tumour-selective cytotoxins.
Colonic Neoplasms
4- [3,5-bis(trimethylsilyl)benzamido] benzoic acid (TAC-101) induced fas expression and activated caspase-3 and -8 in a DLD-1 colon cancer cell line.
Colonic Neoplasms
7,7?-Dimethoxyagastisflavone-induced Apoptotic or Autophagic Cell Death in Different Cancer Cells.
Colonic Neoplasms
?-Lapachone Inhibits Lung Metastasis of Colorectal Cancer by Inducing Apoptosis of CT26 Cells.
Colonic Neoplasms
A ginger derivative, zingerone-a phenolic compound-induces ROS-mediated apoptosis in colon cancer cells (HCT-116).
Colonic Neoplasms
A novel porphyrin photosensitizer from bamboo leaves that induces apoptosis in cancer cell lines.
Colonic Neoplasms
A novel SIRT1 inhibitor, 4bb induces apoptosis in HCT116 human colon carcinoma cells partially by activating p53.
Colonic Neoplasms
A Peptide-Based Positron Emission Tomography Probe for In Vivo Detection of Caspase Activity in Apoptotic Cells.
Colonic Neoplasms
Ac-tLeu-Asp-H is the minimal and highly effective human caspase-3 inhibitor: biological and in silico studies.
Colonic Neoplasms
Acetylcholinesterase expression mediated by c-Jun-NH2-terminal kinase pathway during anticancer drug-induced apoptosis.
Colonic Neoplasms
Acriflavine enhances radiosensitivity of colon cancer cells through endoplasmic reticulum stress-mediated apoptosis.
Colonic Neoplasms
Adenosine suppresses CW2 human colonic cancer growth by inducing apoptosis via A(1) adenosine receptors.
Colonic Neoplasms
Alpha-chaconine, a potato glycoalkaloid, induces apoptosis of HT-29 human colon cancer cells through caspase-3 activation and inhibition of ERK 1/2 phosphorylation.
Colonic Neoplasms
Anti-apoptotic proteins Bcl-2/Bcl-XL inhibit Clostridium difficile toxin A-induced cell death in human epithelial cells.
Colonic Neoplasms
Anti-cancer activity of nitrones in the Apc(Min/+) model of colorectal cancer.
Colonic Neoplasms
Anti-tumor role of Bacillus subtilis fmbJ-derived fengycin on human colon cancer HT29 cell line.
Colonic Neoplasms
Anticancer activity of sclerotiorin, isolated from an endophytic fungus Cephalotheca faveolata Yaguchi, Nishim. & Udagawa.
Colonic Neoplasms
Anticancer effect of fermented Insampaedok-san in human colon cancer cells: a pilot study.
Colonic Neoplasms
Antioxidant Rich Morus alba leaf Extract Induces Apoptosis in Human Colon and Breast Cancer Cells by the Downregulation of Nitric Oxide Produced by Inducible Nitric Oxide Synthase.
Colonic Neoplasms
Antiproliferative effects of combinational therapy of Lycopodium clavatum and quercetin in colon cancer cells.
Colonic Neoplasms
Antitumor effect of resveratrol oligomers against human cancer cell lines and the molecular mechanism of apoptosis induced by vaticanol C.
Colonic Neoplasms
Apoptotic effect of eugenol envolves G2/M phase abrogation accompanied by mitochondrial damage and clastogenic effect on cancer cell in vitro.
Colonic Neoplasms
Apoptotic effect of hesperidin through caspase3 activation in human colon cancer cells, SNU-C4.
Colonic Neoplasms
Apoptotic effect of red wine polyphenols on human colon cancer SNU-C4 cells.
Colonic Neoplasms
Apoptotic Effect of Saccharomyces cerevisiae on Human Colon Cancer SW480 Cells by Regulation of Akt/NF-?B Signaling Pathway.
Colonic Neoplasms
Augmentation of sodium butyrate-induced apoptosis by phosphatidylinositol 3'-kinase inhibition in the KM20 human colon cancer cell line.
Colonic Neoplasms
Autocrine gastrins in colon cancer cells Up-regulate cytochrome c oxidase Vb and down-regulate efflux of cytochrome c and activation of caspase-3.
Colonic Neoplasms
Bax plays a pivotal role in thapsigargin-induced apoptosis of human colon cancer HCT116 cells by controlling Smac/Diablo and Omi/HtrA2 release from mitochondria.
Colonic Neoplasms
Benzo[b]tryptanthrin inhibits MDR1, topoisomerase activity, and reverses adriamycin resistance in breast cancer cells.
Colonic Neoplasms
Berberine regulates the microRNA-21-ITG?4-PDCD4 axis and inhibits colon cancer viability.
Colonic Neoplasms
beta-Lapachone-induced apoptosis is associated with activation of caspase-3 and inactivation of NF-kappaB in human colon cancer HCT-116 cells.
Colonic Neoplasms
Betulin induces cytochrome c release and apoptosis in colon cancer cells via NOXA.
Colonic Neoplasms
Bufalin induces apoptosis via mitochondrial ROS-mediated caspase-3 activation in HCT-116 and SW620 human colon cancer cells.
Colonic Neoplasms
Bufalin induces autophagy-mediated cell death in human colon cancer cells through reactive oxygen species generation and JNK activation.
Colonic Neoplasms
Carbohydrate Modifications of Neoandrographolide for Improved Reactive Oxygen Species-Mediated Apoptosis through Mitochondrial Pathway in Colon Cancer.
Colonic Neoplasms
Cardamonin Sensitizes Tumor Cells to TRAIL Through ROS- and CHOP-Mediated Upregulation of Death Receptors and Downregulation of Survival Proteins.
Colonic Neoplasms
Caspase-3 activity, response to chemotherapy and clinical outcome in patients with colon cancer.
Colonic Neoplasms
Caspase-3 regulates the migration, invasion and metastasis of colon cancer cells.
Colonic Neoplasms
Cedrus deodara (bark) essential oil induces apoptosis in human colon cancer cells by inhibiting Nuclear Factor kappa B.
Colonic Neoplasms
Celastrol inhibits colon cancer cell proliferation by downregulating miR-21 and PI3K/AKT/GSK-3? pathway.
Colonic Neoplasms
Ceramide synthase 6 modulates TRAIL sensitivity and nuclear translocation of active caspase-3 in colon cancer cells.
Colonic Neoplasms
CHOP is involved in endoplasmic reticulum stress-induced apoptosis by enhancing DR5 expression in human carcinoma cells.
Colonic Neoplasms
Citri Reticulatae Viride Pericarpium extract induced apoptosis in SNU-C4, human colon cancer cells.
Colonic Neoplasms
Cleavage of GSDME by caspase-3 determines lobaplatin-induced pyroptosis in colon cancer cells.
Colonic Neoplasms
Conception, synthesis, and characterization of a rofecoxib-combretastatin hybrid drug with potent cyclooxygenase-2 (COX-2) inhibiting and microtubule disrupting activities in colon cancer cell culture and xenograft models.
Colonic Neoplasms
Crude extract of garlic induced caspase-3 gene expression leading to apoptosis in human colon cancer cells.
Colonic Neoplasms
Curcumin-induced apoptosis of human colon cancer colo 205 cells through the production of ROS, Ca2+ and the activation of caspase-3.
Colonic Neoplasms
Design, Synthesis and Antiproliferative Activities of Oxidative Stress Inducers Based on 2-Styryl-3,5-dihydro-4H-imidazol-4-one Scaffold.
Colonic Neoplasms
Diallyl sulfide induces apoptosis in Colo 320 DM human colon cancer cells: involvement of caspase-3, NF-kappaB, and ERK-2.
Colonic Neoplasms
Dicaffeoylquinic acids in Yerba mate (Ilex paraguariensis St. Hilaire) inhibit NF-?B nucleus translocation in macrophages and induce apoptosis by activating caspases-8 and -3 in human colon cancer cells.
Colonic Neoplasms
Diclofenac down-regulates COX-2 induced expression of CD44 and ICAM-1 in human HT29 colorectal cancer cells.
Colonic Neoplasms
Discovery of a novel dual-target inhibitor against RSK1 and MSK2 to suppress growth of human colon cancer.
Colonic Neoplasms
Discovery of a small-molecule protein kinase C?-selective activator with promising application in colon cancer therapy.
Colonic Neoplasms
Discovery of Novel 2-Amino-5-(Substituted)-1,3,4-Thiadiazole Derivatives: New Utilities for Colon Cancer Treatment.
Colonic Neoplasms
Downregulation of NIT2 inhibits colon cancer cell proliferation and induces cell cycle arrest through the caspase-3 and PARP pathways.
Colonic Neoplasms
Effect of bevacizumab on expression level of GLI1 and ING4 in colon cancer animal model.
Colonic Neoplasms
Effective cytotoxic activity of OSW-1 on colon cancer by inducing apoptosis in vitro and in vivo.
Colonic Neoplasms
Efficiency of newly formulated camptothecin with ?-cyclodextrin-EDTA-Fe3O4 nanoparticle-conjugated nanocarriers as an anti-colon cancer (HT29) drug.
Colonic Neoplasms
Enterolactone induces apoptosis and inhibits growth of Colo 201 human colon cancer cells both in vitro and in vivo.
Colonic Neoplasms
Evidence of cell damage induced by major components of a diet-compatible mixture of oxysterols in human colon cancer CaCo-2 cell line.
Colonic Neoplasms
Factor VIIa regulates the expression of caspase-3, MMP-9, and CD44 in SW620 colon cancer cells involving PAR2/MAPKs/NF-?B signaling pathways.
Colonic Neoplasms
Farnesoid X receptor activation induces antitumour activity in colorectal cancer by suppressing JAK2/STAT3 signalling via transactivation of SOCS3 gene.
Colonic Neoplasms
Fish fatty acids alter markers of apoptosis in colorectal adenoma and adenocarcinoma cell lines but fish consumption has no impact on apoptosis-induction ex vivo.
Colonic Neoplasms
Frondoside A Enhances the Anti-Cancer Effects of Oxaliplatin and 5-Fluorouracil on Colon Cancer Cells.
Colonic Neoplasms
Ganoderma lucidum Polysaccharide Enzymatic Hydrolysate Suppresses the Growth of Human Colon Cancer Cells via Inducing Apoptosis.
Colonic Neoplasms
Genistein Induces Apoptosis and Inhibits Proliferation of HT29 Colon Cancer Cells.
Colonic Neoplasms
Growth inhibition of human gynecologic and colon cancer cells by Phyllanthus watsonii through apoptosis induction.
Colonic Neoplasms
Gypenosides induced apoptosis in human colon cancer cells through the mitochondria-dependent pathways and activation of caspase-3.
Colonic Neoplasms
Haeamtang Induces Apoptosis of Colon Cancer HT-29 Cells through Activation of Caspase-3.
Colonic Neoplasms
HUHS1015 Suppresses Colonic Cancer Growth by Inducing Necrosis and Apoptosis in Association with Mitochondrial Damage.
Colonic Neoplasms
Hyaluronic acid-tumor necrosis factor-related apoptosis-inducing ligand conjugate for targeted treatment of liver fibrosis.
Colonic Neoplasms
Hydrogen sulfide protects colon cancer cells from chemopreventative agent beta-phenylethyl isothiocyanate induced apoptosis.
Colonic Neoplasms
In vitro and in vivo inhibitory effects of a Pleurotus eryngii protein on colon cancer cells.
Colonic Neoplasms
In vivo imaging of early stage apoptosis by measuring real-time caspase-3/7 activation.
Colonic Neoplasms
In-silico and in-vitro anti-cancer potential of a curcumin analogue (1E, 6E)-1, 7-di (1H-indol-3-yl) hepta-1, 6-diene-3, 5-dione.
Colonic Neoplasms
Induction of apoptosis in colon cancer cells by cyclooxygenase-2 inhibitor NS398 through a cytochrome c-dependent pathway.
Colonic Neoplasms
Inhibition of autophagy augments 5-fluorouracil chemotherapy in human colon cancer in vitro and in vivo model.
Colonic Neoplasms
Inhibition of hsa_circ_0001313 (circCCDC66) induction enhances the radio-sensitivity of colon cancer cells via tumor suppressor miR-338-3p: Effects of cicr_0001313 on colon cancer radio-sensitivity.
Colonic Neoplasms
Integrated analysis of potential pathways by which aloe-emodin induces the apoptosis of colon cancer cells.
Colonic Neoplasms
Interaction between celecoxib and docetaxel or cisplatin in human cell lines of ovarian cancer and colon cancer is independent of COX-2 expression levels.
Colonic Neoplasms
Isorhamnetin in Tsoong blocks Hsp70 expression to promote apoptosis of colon cancer cells.
Colonic Neoplasms
Lamin B, caspase-3 activity, and apoptosis induction by a combination of HMG-CoA reductase inhibitor and COX-2 inhibitors: a novel approach in developing effective chemopreventive regimens.
Colonic Neoplasms
Leuconostoc mesenteroides-derived anticancer pharmaceuticals hinder inflammation and cell survival in colon cancer cells by modulating NF-?B/AKT/PTEN/MAPK pathways.
Colonic Neoplasms
Loss of caspase-3 sensitizes colon cancer cells to genotoxic stress via RIP1-dependent necrosis.
Colonic Neoplasms
Mechanism of activation of caspase cascade during beta-carotene-induced apoptosis in human tumor cells.
Colonic Neoplasms
Mesalazine causes a mitotic arrest and induces caspase-dependent apoptosis in colon carcinoma cells.
Colonic Neoplasms
Methyl Sartortuoate Inhibits Colon Cancer Cell Growth by Inducing Apoptosis and G2/M-Phase Arrest.
Colonic Neoplasms
miR-1184 regulates the proliferation and apoptosis of colon cancer cells via targeting CSNK2A1.
Colonic Neoplasms
NADPH oxidase overexpression in human colon cancers and rat colon tumors induced by 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine (PhIP).
Colonic Neoplasms
Natural humoral immune response to ribosomal P0 protein in colorectal cancer patients.
Colonic Neoplasms
Necrosis predominates in the cell death of human colon adenocarcinoma HT-29 cells treated under variable conditions of photodynamic therapy with hypericin.
Colonic Neoplasms
Nitric oxide impairs the 17beta-estradiol-induced apoptosis in human colon adenocarcinoma cells.
Colonic Neoplasms
Overexpression of miR-22 reverses paclitaxel-induced chemoresistance through activation of PTEN signaling in p53-mutated colon cancer cells.
Colonic Neoplasms
p21(WAF1/CIP1) inhibits initiator caspase cleavage by TRAIL death receptor DR4.
Colonic Neoplasms
Participation of Omi Htra2 serine-protease activity in the apoptosis induced by cisplatin on SW480 colon cancer cells.
Colonic Neoplasms
Patulin induces colorectal cancer cells apoptosis through EGR-1 dependent ATF3 up-regulation.
Colonic Neoplasms
Periostin induces chemoresistance in colon cancer cells through activation of the PI3K/Akt/survivin pathway.
Colonic Neoplasms
Photodynamic therapy with the phthalocyanine photosensitizer Pc 4 of SW480 human colon cancer xenografts in athymic mice.
Colonic Neoplasms
Pien Tze Huang induced apoptosis in human colon cancer HT-29 cells is associated with regulation of the Bcl-2 family and activation of caspase 3.
Colonic Neoplasms
Pro-apoptotic effect of haem oxygenase-1 in human colorectal carcinoma cells via endoplasmic reticular stress.
Colonic Neoplasms
Protective Effect of Nerium Oleander Distillate and Tarantula Cubensis Alcoholic Extract on Cancer Biomarkers on Colon and Liver Tissues of Rats with Experimental Colon Cancer.
Colonic Neoplasms
Protein kinase C delta is not activated by caspase-3 and its inhibition is sufficient to induce apoptosis in the colon cancer line, COLO 205.
Colonic Neoplasms
PTC-209 Anti-Cancer Effects Involved the Inhibition of STAT3 Phosphorylation.
Colonic Neoplasms
Regulation of caspase expression and apoptosis by adenomatous polyposis coli.
Colonic Neoplasms
Reparative properties of the traditional Chinese medicine Cordyceps sinensis (Chinese caterpillar mushroom) using HT29 cell culture and rat gastric damage models of injury.
Colonic Neoplasms
Role of caspase-3 in apoptosis of colon cancer cells induced by nonsteroidal anti-inflammatory drugs.
Colonic Neoplasms
Short-chain fatty acids induced autophagy serves as an adaptive strategy for retarding mitochondria-mediated apoptotic cell death.
Colonic Neoplasms
Simultaneous inhibition of focal adhesion kinase and SRC enhances detachment and apoptosis in colon cancer cell lines.
Colonic Neoplasms
SMAC mimetics sensitize nonsteroidal anti-inflammatory drug-induced apoptosis by promoting caspase-3-mediated cytochrome c release.
Colonic Neoplasms
Sodium 5,6-benzylidene-L-ascorbate induces oxidative stress, autophagy, and growth arrest in human colon cancer HT-29 cells.
Colonic Neoplasms
STAT3 signaling pathway is necessary for cell survival and tumorsphere forming capacity in ALDH?/CD133? stem cell-like human colon cancer cells.
Colonic Neoplasms
Synergistic Effects of Simvastatin and Irinotecan against Colon Cancer Cells with or without Irinotecan Resistance.
Colonic Neoplasms
Targeted RNA interference of PI3K pathway components sensitizes colon cancer cells to TNF-related apoptosis-inducing ligand (TRAIL).
Colonic Neoplasms
The ?6-integrin-ERK/MAP kinase pathway contributes to chemo resistance in colon cancer.
Colonic Neoplasms
The chemopreventive effect of thymol against dimethylhydrazine and/or high fat diet-induced colon cancer in rats: Relevance to NF-?B.
Colonic Neoplasms
The Curcumin Analogue, MS13 (1,5-Bis(4-hydroxy-3- methoxyphenyl)-1,4-pentadiene-3-one), Inhibits Cell Proliferation and Induces Apoptosis in Primary and Metastatic Human Colon Cancer Cells.
Colonic Neoplasms
The pro-apoptotic effect of quercetin in cancer cell lines requires ER?-dependent signals.
Colonic Neoplasms
The soy-derived peptide Vglycin inhibits the growth of colon cancer cells in vitro and in vivo.
Colonic Neoplasms
Tributyrin, an oral butyrate analogue, induces apoptosis through the activation of caspase-3.
Colonic Neoplasms
Tumor suppressor microRNA-27a in colorectal carcinogenesis and progression by targeting SGPP1 and Smad2.
Colonic Neoplasms
Tumor suppressor XIAP-Associated factor 1 (XAF1) cooperates with tumor necrosis factor-related apoptosis-inducing ligand to suppress colon cancer growth and trigger tumor regression.
Colonic Neoplasms
Upregulation of the antiapoptotic factor Livin contributes to cisplatin resistance in colon cancer cells.
Colonic Neoplasms
Ursodeoxycholic acid increases the activities of alkaline sphingomyelinase and caspase-3 in the rat colon.
Colonic Neoplasms
Ursolic Acid Inhibits Tumor Growth via Epithelial-to-Mesenchymal Transition in Colorectal Cancer Cells.
Colonic Neoplasms
Ursolic acid simultaneously targets multiple signaling pathways to suppress proliferation and induce apoptosis in colon cancer cells.
Colonic Neoplasms
[Down-regulation of sphingosine kinase 1 (SphK1) enhances the chemosensitivity to cisplatin in human colon cancer RKO cells].
Colorectal Neoplasms
3-(Benzo[d][1,3]dioxol-5-ylamino)-N-(4-fluorophenyl)thiophene-2-carboxamide overcomes cancer chemoresistance via inhibition of angiogenesis and P-glycoprotein efflux pump activity.
Colorectal Neoplasms
?-Linolenic and ?-linolenic acids exercise differential antitumor effects on HT-29 human colorectal cancer cells.
Colorectal Neoplasms
?-Tocotrienol and 6-Gingerol in Combination Synergistically Induce Cytotoxicity and Apoptosis in HT-29 and SW837 Human Colorectal Cancer Cells.
Colorectal Neoplasms
A caspase-3 'death-switch' in colorectal cancer cells for induced and synchronous tumor apoptosis in vitro and in vivo facilitates the development of minimally invasive cell death biomarkers.
Colorectal Neoplasms
A novel small molecule inhibits STAT3 phosphorylation and DNA binding activity and exhibits potent growth suppressive activity in human cancer cells.
Colorectal Neoplasms
Active caspase 3 and DNA fragmentation as markers for apoptotic cell death in primary and metastatic liver tumours.
Colorectal Neoplasms
Anti-cancer effects of recombinant arazyme from Serratia Proteomaculans.
Colorectal Neoplasms
Antibody against N-terminal domain of phospholipid scramblase 1 induces apoptosis in colorectal cancer cells through the intrinsic apoptotic pathway.
Colorectal Neoplasms
Anticancer potential of limonoids from Swietenia macrophylla: Genotoxic, antiproliferative and proapoptotic effects towards human colorectal cancer.
Colorectal Neoplasms
Apoptosis as a Prognostic Factor in Colorectal Carcinoma: Comparison of TUNEL Method and Immunohistochemical Expression of Caspase-3.
Colorectal Neoplasms
Autophagy enhances the aggressiveness of human colorectal cancer cells and their ability to adapt to apoptotic stimulus.
Colorectal Neoplasms
Baicalin and the liver-gut system: Pharmacological bases explaining its therapeutic effects.
Colorectal Neoplasms
Berry anthocyanins reduce proliferation of human colorectal carcinoma cells by inducing caspase-3 activation and p21 upregulation.
Colorectal Neoplasms
Characterization of [(99m)Tc]Duramycin as a SPECT Imaging Agent for Early Assessment of Tumor Apoptosis.
Colorectal Neoplasms
Combined inhibition of FLIP and XIAP induces Bax-independent apoptosis in type II colorectal cancer cells.
Colorectal Neoplasms
Diallyl trisulfide induces apoptosis in human primary colorectal cancer cells.
Colorectal Neoplasms
Effective Targeting Survivin, Caspase-3 and MicroRNA-16-1 Expression by Methyl-3-pentyl-6-methoxyprodigiosene Triggers Apoptosis in Colorectal Cancer Stem-Like Cells.
Colorectal Neoplasms
Effects of Hydroxytyrosol on Expression of Apoptotic Genes and Activity of Antioxidant Enzymes in LS180 Cells.
Colorectal Neoplasms
Effects of Hypericum perforatum extract on oxaliplatin-induced neurotoxicity: in vitro evaluations.
Colorectal Neoplasms
Elevated cleaved caspase-3 is associated with shortened overall survival in several cancer types.
Colorectal Neoplasms
EMAP-II-dependent lymphocyte killing is associated with hypoxia in colorectal cancer.
Colorectal Neoplasms
Expression of p53 and DR5 in normal and malignant tissues of colorectal cancer: Correlation with advanced stages.
Colorectal Neoplasms
EZH2 inhibition promotes methyl jasmonate-induced apoptosis of human colorectal cancer through the Wnt/?-catenin pathway.
Colorectal Neoplasms
Flavone inhibition of tumor growth via apoptosis in vitro and in vivo.
Colorectal Neoplasms
Fluorescence lifetime imaging microscopy of chemotherapy-induced apoptosis resistance in a syngenic mouse tumor model.
Colorectal Neoplasms
Heat shock protein 27 is associated with irinotecan resistance in human colorectal cancer cells.
Colorectal Neoplasms
Helveticoside Exhibited p53-dependent Anticancer Activity Against Colorectal Cancer.
Colorectal Neoplasms
Hemistepsin A suppresses colorectal cancer growth through inhibiting pyruvate dehydrogenase kinase activity.
Colorectal Neoplasms
High levels of cleaved caspase-3 in colorectal tumour stroma predict good survival.
Colorectal Neoplasms
Implications of cleaved caspase 3 and AIF expression in colorectal cancer based on patient age.
Colorectal Neoplasms
In vitro anti-tumor effect of high-fluence low-power laser light on apoptosis of human colorectal cancer cells.
Colorectal Neoplasms
Increased apoptosis in infiltrating mononuclear cells of colorectal cancer: a mechanism for tumor escape.
Colorectal Neoplasms
Increased HMGB1 and cleaved caspase-3 stimulate the proliferation of tumor cells and are correlated with the poor prognosis in colorectal cancer.
Colorectal Neoplasms
Induction of caspase-3 protease activity and apoptosis by butyrate and trichostatin A (inhibitors of histone deacetylase): dependence on protein synthesis and synergy with a mitochondrial/cytochrome c-dependent pathway.
Colorectal Neoplasms
Libidibia ferrea presents antiproliferative, apoptotic and antioxidant effects in a colorectal cancer cell line.
Colorectal Neoplasms
Loss of caspase-3 sensitizes colon cancer cells to genotoxic stress via RIP1-dependent necrosis.
Colorectal Neoplasms
Low levels of Caspase-3 predict favourable response to 5FU-based chemotherapy in advanced colorectal cancer: Caspase-3 inhibition as a therapeutic approach.
Colorectal Neoplasms
Low-dose radiation hypersensitivity is associated with p53-dependent apoptosis.
Colorectal Neoplasms
M51R and Delta-M51 matrix protein of the vesicular stomatitis virus induce apoptosis in colorectal cancer cells.
Colorectal Neoplasms
Matrine induces apoptosis in multiple colorectal cancer cell lines in vitro and inhibits tumour growth with minimum side effects in vivo via Bcl-2 and caspase-3.
Colorectal Neoplasms
Mechanisms of grape seed procyanidin-induced apoptosis in colorectal carcinoma cells.
Colorectal Neoplasms
Methanolic extract of Artemisia absinthium prompts apoptosis, enhancing expression of Bax/Bcl-2 ratio, cell cycle arrest, caspase-3 activation and mitochondrial membrane potential destruction in human colorectal cancer HCT-116 cells.
Colorectal Neoplasms
Microbiota Composition, HSP70 and Caspase-3 Expression as Marker for Colorectal Cancer Patients in Aceh, Indonesia.
Colorectal Neoplasms
MicroRNA-421 Inhibits Apoptosis by Downregulating Caspase-3 in Human Colorectal Cancer.
Colorectal Neoplasms
miR-224 Is Significantly Upregulated and Targets Caspase-3 and Caspase-7 During Colorectal Carcinogenesis.
Colorectal Neoplasms
Moderate DNA hypomethylation suppresses intestinal tumorigenesis by promoting caspase-3 expression and apoptosis.
Colorectal Neoplasms
Modulating Pluripotency Network Genes with Omega-3 DHA is Followed by Caspase-3 Activation and Apoptosis in DNA Mismatch Repair-Deficient/KRAS-Mutant Colorectal Cancer Stem-Like Cells Modulating Pluripotency Network Genes with DHA
Colorectal Neoplasms
Modulating Survivin as a Radioresistant Factor, Caspase-3, and Apoptosis by Omega-3 Docosahexaenoic Acid Sensitizes Mutant-p53 Colorectal Cancer Cells to ?-Irradiation.
Colorectal Neoplasms
Molecular docking data of piperine with Bax, Caspase 3, Cox 2 and Caspase 9.
Colorectal Neoplasms
Mutational analysis of the CASP6 gene in colorectal and gastric carcinomas.
Colorectal Neoplasms
Natural oncolytic activity of live-attenuated measles virus against human lung and colorectal adenocarcinomas.
Colorectal Neoplasms
New structural analogues of curcumin exhibit potent growth suppressive activity in human colorectal carcinoma cells.
Colorectal Neoplasms
Physicochemical characterization and antitumour activity of exopolysaccharides produced by Lactobacillus casei SB27 from yak milk.
Colorectal Neoplasms
PinX1 without the G-patch motif suppresses proliferation, induces senescence, but does not inhibit telomerase activity in colorectal cancer SW480 cells.
Colorectal Neoplasms
PPARgamma is a key target of butyrate-induced caspase-3 activation in the colorectal cancer cell line Caco-2.
Colorectal Neoplasms
Prognostic value of Caspase-3 expression in cancers of digestive tract: a meta-analysis and systematic review.
Colorectal Neoplasms
Quantitative imaging of apoptosis commitment in colorectal tumor cells.
Colorectal Neoplasms
Reactive Oxygen Species and p53 Mediated Activation of p38 and Caspases is Critically Involved in Kaempferol Induced Apoptosis in Colorectal Cancer Cells.
Colorectal Neoplasms
Redistribution of activated caspase-3 to the nucleus during butyric acid-induced apoptosis.
Colorectal Neoplasms
Synergetic Inhibition of Human Colorectal Cancer Cells by Combining Polyyne-Enriched Fraction from Oplopanax elatus and Irinotecan.
Colorectal Neoplasms
Synergistic role of Caspase-8 and Caspase-3 expressions: Prognostic and predictive biomarkers in colorectal cancer.
Colorectal Neoplasms
Systematic high-content proteomic analysis reveals substantial immunologic changes in colorectal cancer.
Colorectal Neoplasms
The depletion of securin enhances butein-induced apoptosis and tumor inhibition in human colorectal cancer.
Colorectal Neoplasms
The effect of celecoxib and its combination with imatinib on human HT-29 colorectal cancer cells: Involvement of COX-2, Caspase-3, VEGF and NF-?B genes expression.
Colorectal Neoplasms
The presumed MTH1-inhibitor TH588 sensitizes colorectal carcinoma cells to ionizing radiation in hypoxia.
Colorectal Neoplasms
The prognostic significance of Caspase-3 and survivin expression in colorectal cancer patients.
Colorectal Neoplasms
The Value of Caspase-3 after the Application of Annona muricata Leaf Extract in COLO-205 Colorectal Cancer Cell Line.
Colorectal Neoplasms
Treatment of LS174T colorectal cancer stem-like cells with n-3 PUFAs induces growth suppression through inhibition of survivin expression and induction of caspase-3 activation.
Colorectal Neoplasms
Treatment of undifferentiated colorectal cancer cells with fish-oil derived docosahexaenoic acid triggers caspase-3 activation and apoptosis.
Colorectal Neoplasms
Water extract of brewers' rice induces apoptosis in human colorectal cancer cells via activation of caspase-3 and caspase-8 and downregulates the Wnt/?-catenin downstream signaling pathway in brewers' rice-treated rats with azoxymethane-induced colon carcinogenesis.
Colorectal Neoplasms
[Adiponectin inhibits proliferation and induces apoptosis in colorectal cancer HCT116 cells].
Colorectal Neoplasms
[Amentoflavone induces apoptosis in SW480 human colorectal cancer cells via regulating ?-catenin and caspase-3 expressions].
Colorectal Neoplasms
[Expression of AIF and caspase-3 in colorectal carcinoma, adenoma, and normal mucosa and its correlation]
Colorectal Neoplasms
[Study on the apoptosis and its mechanism of lovo human colorectal cancer cells induced by SFPS]
Coma
The combination of exercise training and alpha-lipoic acid treatment has therapeutic effects on the pathogenic phenotypes of Alzheimer's disease in NSE/APPsw-transgenic mice.
Communicable Diseases
Increased levels of circulating IL-16 and apoptosis markers are related to the activity of Whipple's disease.
Congenital Abnormalities
Calcium Alleviates Fluoride-Induced Bone Damage by Inhibiting Endoplasmic Reticulum Stress and Mitochondrial Dysfunction.
Congenital Abnormalities
[Effects of electroacupuncture on cerebral Bcl-2 and caspase-3 expression after cerebral ischemia reperfusion in rats]
Conjunctivitis
Methylene Blue Inhibits Acute Hemorrhagic Conjunctivitis Virus Production and Induction of Caspase-3 Mediated Human Corneal Cell Cytopathy.
Conjunctivitis, Acute Hemorrhagic
Methylene Blue Inhibits Acute Hemorrhagic Conjunctivitis Virus Production and Induction of Caspase-3 Mediated Human Corneal Cell Cytopathy.
Contracture
A peptide inhibitor of c-Jun NH2-terminal kinase reduces myocardial ischemia-reperfusion injury and infarct size in vivo.
Corneal Neovascularization
Trehalose treatment accelerates the healing of UVB-irradiated corneas. Comparative immunohistochemical studies on corneal cryostat sections and corneal impression cytology.
Coronary Artery Disease
Early inhibition of caspase-3 activity lessens the development of graft coronary artery disease.
Coronary Artery Disease
Hyperglycaemia-associated Caspase-3 predicts diabetes and coronary artery disease events.
Coronary Disease
Homocysteine-induced caspase-3 activation by endoplasmic reticulum stress in endothelial progenitor cells from patients with coronary heart disease and healthy donors.
Coronary Disease
[Effect of Gualou Xiebai Banxia decoction combined with Xuefu Zhuyu decoction on myocardial apoptosis and relevant protein expressions in miniature swine phlegm and blood stasis type coronary heart disease model].
Coronary Occlusion
Pretreatment with hyperoxia reduces in vivo infarct size and cell death by apoptosis with an early and delayed phase of protection.
Coronavirus Infections
Porcine hemagglutinating encephalomyelitis virus induces apoptosis in a porcine kidney cell line via caspase-dependent pathways.
COVID-19
COVID-19 and male reproductive function: a prospective, longitudinal cohort study.
COVID-19
Endothelial cell damage is the central part of COVID-19 and a mouse model induced by injection of the S1 subunit of the spike protein.
COVID-19
Improving the Understanding of the Immunopathogenesis of Lymphopenia as a Correlate of SARS-CoV-2 Infection Risk and Disease Progression in African Patients: Protocol for a Cross-sectional Study.
COVID-19
Potential mechanism underlying the effect of matrine on COVID-19 patients revealed through network pharmacological approaches and molecular docking analysis.
COVID-19
Potential mechanisms of Chinese Herbal Medicine that implicated in the treatment of COVID-19 related renal injury.
COVID-19
Revealing the therapeutic targets and molecular mechanisms of emodin-treated coronavirus disease 2019 via a systematic study of network pharmacology.
COVID-19
Review on the potential action mechanisms of Chinese medicines in treating Coronavirus Disease 2019 (COVID-19).
COVID-19
[Mechanism of QingfeiPaidu decoction for treatment of COVID-19: analysis based on network pharmacology and molecular docking technology].
Cowpox
Role and regulation of activation of caspases in cisplatin-induced injury to renal tubular epithelial cells.
Cowpox
The cytotoxic cell protease granzyme B initiates apoptosis in a cell-free system by proteolytic processing and activation of the ICE/CED-3 family protease, CPP32, via a novel two-step mechanism.
Craniocerebral Trauma
Increases in Bcl-2 and cleavage of caspase-1 and caspase-3 in human brain after head injury.
Craniocerebral Trauma
Nitric oxide and cell signaling: in vivo evaluation of NO-dependent apoptosis by MRI and not NMR techniques.
Craniocerebral Trauma
The anti-inflammatory and anti-apoptotic effects of nesfatin-1 in the traumatic rat brain.
Craniocerebral Trauma
[INVOLVEMENT OF EPIGENETIC REGULATION IN CEREBRAL CELL DEATH FOLLOWING TRAUMATIC BRAIN INJURY IN A RAT MODEL].
Creutzfeldt-Jakob Syndrome
Expression of excitatory amino acid transporter-1 (EAAT-1) in brain macrophages and microglia of patients with prion diseases.
Crohn Disease
Anti-TNF antibodies do not induce the apoptosis of lamina propria mononuclear cells in uninflamed intestinal tissue in patients with Crohn's disease.
Crohn Disease
Arsenic trioxide reduces 2,4,6-trinitrobenzene sulfonic acid-induced murine colitis via nuclear factor-{kappa}B down-regulation and caspase-3 activation.
Crohn Disease
Imbalance of Controlled Death in Peripheral Blood Lymphocytes in Crohn's Disease and Ulcerative Colitis.
Crohn Disease
Inflammation-induced Occludin Downregulation Limits Epithelial Apoptosis by Suppressing Caspase 3 Expression.
Crohn Disease
Infliximab but not etanercept induces apoptosis in lamina propria T-lymphocytes from patients with Crohn's disease.
Cryptorchidism
Phospholipid hydroperoxide glutathione peroxidase is involved in the maintenance of male fertility under cryptorchidism in mice.
Cushing Syndrome
[Effect of adrenocorticotropic hormone on the caspase-3 level and DNA fragmentation in hyperplasia tissue of human adrenals]
Cystic Fibrosis
CFTR Regulation of Intracellular pH and Ceramides is Required for Lung Endothelial Cell Apoptosis.
Cystic Fibrosis
Effects of early and late pneumothorax drainage on the development of pulmonary oedema.
Cysticercosis
Detection of cysteine protease in Taenia solium-induced brain granulomas in naturally infected pigs.
Cysts
Apoptosis as a possible mechanism of infertility in Echinococcus granulosus hydatid cysts.
Cysts
Chronic effects of maternal tobacco-smoke exposure and/or ?-lipoic acid treatment on reproductive parameters in female rat offspring.
Cysts
Comparative Immunohistochemical Analyses on the Modes of Cell Death/Keratinization in Epidermal Cyst, Trichilemmal Cyst, and Pilomatricoma.
Cysts
Different responses in transformation of MDCK cells in 2D and 3D culture by v-Src as revealed by microarray techniques, RT-PCR and functional assays.
Cysts
Effects of inhibition of vascular endothelial growth factor at time of selection on follicular angiogenesis, expansion, development and atresia in the marmoset.
Cysts
Immunohistochemical profile of the anti-apoptosis, apoptosis and proliferation markers Bcl-2, caspase-3, p53, and Ki-67 in botryoid odontogenic cysts compared to lateral periodontal cysts and gingival cysts of the adult.
Cysts
Intracameral toxicity of bacterial components muramyl dipeptide and staurosporine: ciliary cyst formation, epithelial cell apoptosis and necrosis.
Cysts
Irregularly shaped inclusion cysts display increased expression of Ki67, Fas, Fas ligand, and procaspase-3 but relatively little active caspase-3.
Cysts
The study of apoptotic bifunctional effects in relationship between host and parasite in cystic echinococcosis: a new approach to suppression and survival of hydatid cyst.
Cysts
Tumor necrosis factor receptor-mediated apoptosis in Trichinella spiralis-infected muscle cells.
Deafness
Melody, an ENU mutation in Caspase 3, alters the catalytic cysteine residue and causes sensorineural hearing loss in mice.
Dehydration
The effect of long-term dehydration and subsequent rehydration on markers of inflammation, oxidative stress and apoptosis in the camel kidney.
Delirium
Isoflurane-induced apoptosis: a potential pathogenic link between delirium and dementia.
Dementia
Isoflurane-induced apoptosis: a potential pathogenic link between delirium and dementia.
Dementia
miR-203 inhibitor ameliorates traumatic brain injury by targeting dementia markers and inhibiting neuronal apoptosis.
Dementia
Morin post-treatment confers neuroprotection in a novel rat model of mild repetitive traumatic brain injury by targeting dementia markers, APOE, autophagy and Wnt/?-catenin signaling pathway.
Dementia, Multi-Infarct
N-methyl-D-aspartate receptor and apoptosis in Alzheimer's disease and multiinfarct dementia.
Dementia, Vascular
Inflammation, apoptosis and autophagy as critical players in vascular dementia.
Dementia, Vascular
Ligustrazine suppresses neuron apoptosis via the Bax/Bcl-2 and caspase-3 pathway in PC12 cells and in rats with vascular dementia.
Dementia, Vascular
Therapeutic Effects of Salidroside on Cognitive Ability in Rats with Experimental Vascular Dementia.
Dementia, Vascular
[Effect of triptolide on cognitive dysfunction in vascular dementia rats through SIRT1/NF-?B signaling pathway].
Demyelinating Diseases
Aerobic exercise training decreases cognitive impairment caused by demyelination by regulating ROCK signaling pathway in aging mice.
Demyelinating Diseases
Heparin Reduces Neuroinflammation and Transsynaptic Neuronal Apoptosis in a Model of Subarachnoid Hemorrhage.
Demyelinating Diseases
Inhibition of oligodendrocyte apoptosis by sublytic C5b-9 is associated with enhanced synthesis of bcl-2 and mediated by inhibition of caspase-3 activation.
Demyelinating Diseases
LINGO-1 siRNA nanoparticles promote central remyelination in ethidium bromide-induced demyelination in rats.
Demyelinating Diseases
New Cortical Neurodegenerative Pathways in the Hypertensive Rat Brain.
Demyelinating Diseases
Peripheral neuropathy in the Twitcher mouse involves the activation of axonal caspase 3.
Demyelinating Diseases
Protective effect of gliclazide on diabetic peripheral neuropathy through Drp-1 mediated-oxidative stress and apoptosis.
Demyelinating Diseases
Synergistic effects of pomegranate juice and atorvastatin for improving cerebellar structure and function of breast-feeding rats maternally fed on a high cholesterol diet.
Demyelinating Diseases
Vitamins E and D3 Attenuate Demyelination and Potentiate Remyelination Processes of Hippocampal Formation of Rats Following Local Injection of Ethidium Bromide.
Dengue
FasL/Fas pathway is involved in dengue virus induced apoptosis of the vascular endothelial cells.
Dentigerous Cyst
Role of HIF-1? and CASPASE-3 in cystogenesis of odontogenic cysts and tumors.
Dermatitis, Atopic
Epidermal caspase-3 cleavage associated with interferon-gamma-expressing lymphocytes in acute atopic dermatitis lesions.
Dermatitis, Contact
Caspase inhibitors: a review of recently patented compounds (2013-2015).
Dermatitis, Phototoxic
Chlorin Nanoparticles for Tissue Diagnostics and Photodynamic Therapy.
Dermatitis, Phototoxic
Role of type I & type II reactions in DNA damage and activation of caspase 3 via mitochondrial pathway induced by photosensitized benzophenone.
Diabetes Mellitus
Absence of Caspase-3 Protects Against Denervation Induced Skeletal Muscle Atrophy.
Diabetes Mellitus
Atorvastatin Alleviates Experimental Diabetic Cardiomyopathy by Regulating the GSK-3?-PP2Ac-NF-?B Signaling Axis.
Diabetes Mellitus
Autophagy in ovary and polycystic ovary syndrome: role, dispute and future perspective.
Diabetes Mellitus
Glucose variability aggravates cardiac fibrosis by altering AKT signalling path.
Diabetes Mellitus
Impact of maternal diabetes type 1 on proliferative potential, differentiation and apoptotic activity in villous capillaries of term placenta.
Diabetes Mellitus
Possible link between the cognitive dysfunction associated with diabetes mellitus and the neurotoxicity of methylglyoxal.
Diabetes Mellitus
Protective effects of Purendan superfine powder on retinal neuron apoptosis in a rat model of type 2 diabetes mellitus.
Diabetes Mellitus
The role of polyol pathway in high glucose-induced endothelial cell damages.
Diabetes Mellitus
Type 2 diabetes mellitus induces congenital heart defects in murine embryos by increasing oxidative stress, endoplasmic reticulum stress and apoptosis.
Diabetes Mellitus
[Intensity of apoptotic processes, aconitate hydratase activity and citrate level in patients with type 2 diabetes mellitus complicated steatohepatitis under application of epifamin at basic therapy].
Diabetes Mellitus, Type 1
Atorvastatin Alleviates Experimental Diabetic Cardiomyopathy by Regulating the GSK-3?-PP2Ac-NF-?B Signaling Axis.
Diabetes Mellitus, Type 1
Caspase-3-dependent beta-cell apoptosis in the initiation of autoimmune diabetes mellitus.
Diabetes Mellitus, Type 1
CTRP9 Regulates Growth, Differentiation, and Apoptosis in Human Keratinocytes through TGF?1-p38-Dependent Pathway.
Diabetes Mellitus, Type 1
Defective lymphocyte caspase-3 expression in type 1 diabetes mellitus.
Diabetes Mellitus, Type 1
Expression of Activating Transcription Factor 3 (ATF 3) and caspase 3 in Schwann cells and axonal outgrowth after sciatic nerve repair in diabetic BB rats.
Diabetes Mellitus, Type 1
Immunohistochemical study of caspase-3-expressing cells within the pancreas of non-obese diabetic mice during cyclophosphamide-accelerated diabetes.
Diabetes Mellitus, Type 1
MicroRNA 21 targets BCL2 mRNA to increase apoptosis in rat and human beta cells.
Diabetes Mellitus, Type 1
Orexin-1 receptor co-localizes with pancreatic hormones in islet cells and modulates the outcome of streptozotocin-induced diabetes mellitus.
Diabetes Mellitus, Type 2
Autophagy in ovary and polycystic ovary syndrome: role, dispute and future perspective.
Diabetes Mellitus, Type 2
Erythrocyte caspase-3 activation and oxidative imbalance in erythrocytes and in plasma of type 2 diabetic patients.
Diabetes Mellitus, Type 2
Erythrocyte caspase-3 and antioxidant defense is activated in red blood cells and plasma of type 2 diabetes patients at first clinical onset.
Diabetes Mellitus, Type 2
Exendin-4 stimulates autophagy in pancreatic ?-cells via the RAPGEF/EPAC-Ca2+-PPP3/calcineurin-TFEB axis.
Diabetes Mellitus, Type 2
Hyperglycaemia-associated Caspase-3 predicts diabetes and coronary artery disease events.
Diabetes Mellitus, Type 2
Involvement of microRNA-133 and -29 in cardiac disturbances in diabetic ovariectomized rats.
Diabetes Mellitus, Type 2
Metabolic Stress Induces Caspase-3 Mediated Degradation and Inactivation of Farnesyl and Geranylgeranyl Transferase Activities in Pancreatic ?-Cells.
Diabetes Mellitus, Type 2
The inhibitory effects of soybean isoflavones on testicular cell apoptosis in mice with type 2 diabetes.
Diabetes Mellitus, Type 2
Type 2 diabetes mellitus induces congenital heart defects in murine embryos by increasing oxidative stress, endoplasmic reticulum stress and apoptosis.
Diabetes Mellitus, Type 2
Variations of thioredoxin system contributes to increased susceptibility to apoptosis in cardiomyocytes of type 2 diabetic rats.
Diabetes Mellitus, Type 2
[Intensity of apoptotic processes, aconitate hydratase activity and citrate level in patients with type 2 diabetes mellitus complicated steatohepatitis under application of epifamin at basic therapy].
Diabetes, Gestational
Ferulic acid confers protection on islet ? cells and placental tissues of rats with gestational diabetes mellitus.
Diabetic Cardiomyopathies
Changes in the expression of cardiac mitofusin-2 in different stages of diabetes in rats.
Diabetic Cardiomyopathies
Combination of Morroniside and Diosgenin Prevents High Glucose-Induced Cardiomyocytes Apoptosis.
Diabetic Cardiomyopathies
Streptozotocin-induced diabetic cardiomyopathy in rats: ameliorative effect of PIPERINE via Bcl2, Bax/Bcl2, and caspase-3 pathways.
Diabetic Nephropathies
Andrographolide and 14-deoxy-11,12-didehydroandrographolide from Andrographis paniculata attenuate high glucose-induced fibrosis and apoptosis in murine renal mesangeal cell lines.
Diabetic Nephropathies
Caspase-3 Promotes Diabetic Kidney Disease Through Gasdermin E-Mediated Progression to Secondary Necrosis During Apoptosis.
Diabetic Nephropathies
Effects of enalapril and paricalcitol treatment on diabetic nephropathy and renal expressions of TNF-?, p53, caspase-3 and Bcl-2 in STZ-induced diabetic rats.
Diabetic Nephropathies
Galangin protects against oxidative damage and attenuates inflammation and apoptosis via modulation of NF-?B p65 and caspase-3 signaling molecules in a rat model of diabetic nephropathy.
Diabetic Nephropathies
High glucose-induced oxidative stress causes apoptosis in proximal tubular epithelial cells and is mediated by multiple caspases.
Diabetic Nephropathies
Moderate exercise attenuates caspase-3 activity, oxidative stress, and inhibits progression of diabetic renal disease in db/db mice.
Diabetic Nephropathies
Saxagliptin protects against diabetic nephropathy by inhibiting caspase 3/PARP-1-dependent nephrocyte apoptosis.
Diabetic Nephropathies
The effects of angiotensin-II receptor blockers on podocyte damage and glomerular apoptosis in a rat model of experimental streptozotocin-induced diabetic nephropathy.
Diabetic Nephropathies
The role of apurinic/apyrimidinic endonuclease on the progression of streptozotocin-induced diabetic nephropathy in rats.
Diabetic Retinopathy
Correlations of the severity of diabetic retinopathy with EPO, Caspase-3 expression and oxidative stress.
Diabetic Retinopathy
Exploring the Mechanism of Action Compound-Xueshuantong Capsule in Diabetic Retinopathy Treatment Based on Network Pharmacology.
Diabetic Retinopathy
Minocycline reduces proinflammatory cytokine expression, microglial activation, and caspase-3 activation in a rodent model of diabetic retinopathy.
Diabetic Retinopathy
Role of the intrinsic apoptotic pathway in cataractogenesis in type 2 diabetic patients.
Diabetic Retinopathy
The role of polyol pathway in glucose-induced apoptosis of cultured retinal pericytes.
Diabetic Retinopathy
[The effects of caspase-3 in apoptosis of cultured retinal microvascular pericytes induced by advanced glycation end products]
Diffuse Axonal Injury
8-hydroxy-2-(di-n-propylamino)tetralin intervenes with neural cell apoptosis following diffuse axonal injury.
Diffuse Axonal Injury
Temporal characterisation of pro- and anti-apoptotic mechanisms following diffuse traumatic brain injury in rats.
Diphtheria
Anti-tumor effects of a recombinant anti-prostate specific membrane antigen immunotoxin against prostate cancer cells.
Diphtheria
Targeted therapy to the IL-2R using diphtheria toxin and caspase-3 fusion proteins modulates Treg and ameliorates inflammatory colitis.
Distemper
Canine distemper virus induces apoptosis through caspase-3 and -8 activation in vero cells.
Down Syndrome
Activation of caspase-3 in single neurons and autophagic granules of granulovacuolar degeneration in Alzheimer's disease. Evidence for apoptotic cell death.
Down Syndrome
Caspase-cleaved amyloid precursor protein and activated caspase-3 are co-localized in the granules of granulovacuolar degeneration in Alzheimer's disease and Down's syndrome brain.
Down Syndrome
Overexpression of the chromosome 21 transcription factor Ets2 induces neuronal apoptosis.
Down Syndrome
Unaltered expression of Fas (CD95/APO-1), caspase-3, Bcl-2 and annexins in brains of fetal Down syndrome: evidence against increased apoptosis.
Down Syndrome
Vitamin D3 increases the Caspase-3 p12, MTHFR, and P-glycoprotein reducing amyloid-?42 in the kidney of a mouse model for Down syndrome.
Drug Resistant Epilepsy
Alterations in bcl-2 and caspase gene family protein expression in human temporal lobe epilepsy.
Drug-Related Side Effects and Adverse Reactions
Caspase inhibition switches doxorubicin-induced apoptosis to senescence.
Drug-Related Side Effects and Adverse Reactions
Omega-3 fatty acids, EPA and DHA induce apoptosis and enhance drug sensitivity in multiple myeloma cells but not in normal peripheral mononuclear cells.
Dry Eye Syndromes
Topical cyclosporine inhibits conjunctival epithelial apoptosis in experimental murine keratoconjunctivitis sicca.
Dysentery
Apoptosis in acute shigellosis is associated with increased production of Fas/Fas ligand, perforin, caspase-1, and caspase-3 but reduced production of Bcl-2 and interleukin-2.
Dysentery, Bacillary
Apoptosis in acute shigellosis is associated with increased production of Fas/Fas ligand, perforin, caspase-1, and caspase-3 but reduced production of Bcl-2 and interleukin-2.
Dyskinesias
Activation of striatal inflammatory mediators and caspase-3 is central to haloperidol-induced orofacial dyskinesia.
Dyslipidemias
Integrins ?4?1 and ?V?3 are Reduced in Endothelial Progenitor Cells from Diabetic Dyslipidemic Mice and May Represent New Targets for Therapy in Aortic Valve Disease.
Dystonia
[Effect of a complex treatment, including glutargin and erbisol on the blood plasma content of protein P53, apoptotic markers of type II, activity of caspases and the level of sCD 117 in patients with autonomic-vascular dystonia]
e2 ubiquitin-conjugating enzyme deficiency
UbcH10 overexpression increases carcinogenesis and blocks ALLN susceptibility in colorectal cancer.
Echinococcosis
Post-immunization immunohistochemical expression of Caspase 3 and p53 apoptotic markers in experimental hydatidosis.
Ectromelia
Ectromelia virus virulence factor p28 acts upstream of caspase-3 in response to UV light-induced apoptosis.
Ectropion
Synergetic suppression effects upon the combination of UV-C irradiation and berberine on Microcystis aeruginosa and Scenedesmus obliquus in reclaimed water: Effectiveness and mechanisms.
Ectropion
The Curcumin Analogs 2-Pyridyl Cyclohexanone Induce Apoptosis via Inhibition of the JAK2-STAT3 Pathway in Human Esophageal Squamous Cell Carcinoma Cells.
Ehrlichiosis
Specific processing of poly(ADP-ribose) polymerase, accompanied by activation of caspase-3 and elevation/reduction of ceramide/hydrogen peroxide levels, during induction of apoptosis in host HL-60 cells infected by the human granulocytic ehrlichiosis (HGE) agent.
Embolism
3-[2-[4-(3-Chloro-2-methylphenylmethyl)-1-piperazinyl]ethyl]-5,6-dimethoxy-1-(4-imidazolylmethyl)-1H-indazole dihydro-chloride 3.5 hydrate (DY-9760e) is neuroprotective in rat microsphere embolism: role of the cross-talk between calpain and caspase-3 through calpastatin.
Embolism
Establishing a new rat model of central venous sinus thrombosis and analyzing its pathophysiological and apoptotic changes.
Embryo Loss
MicroRNA-24 inhibits CDX1 expression in decidual tissues of recurrent spontaneous abortion mice to reduce the abortion risk.
Encephalitis
Apoptotic inducement of neuronal cells by codeine: possible role of disrupted redox state and caspase 3 signaling.
Encephalitis
Death receptor-mediated apoptotic signaling is activated in the brain following infection with West Nile virus in the absence of a peripheral immune response.
Encephalitis
Estrogen treatment following severe burn injury reduces brain inflammation and apoptotic signaling.
Encephalitis
Expression of caspase-3 in brains from paediatric patients with HIV-1 encephalitis.
Encephalitis
Platelet-activating factor receptor is essential for the development of experimental cerebral malaria.
Encephalitis, Japanese
Japanese encephalitis virus NS2B-NS3 protease induces caspase 3 activation and mitochondria-mediated apoptosis in human medulloblastoma cells.
Encephalitis, Japanese
Minocycline neuroprotects, reduces microglial activation, inhibits caspase 3 induction, and viral replication following Japanese encephalitis.
Encephalitis, Japanese
Rana catesbeiana ribonuclease inhibits Japanese encephalitis virus (JEV) replication and enhances apoptosis of JEV-infected BHK-21 cells.
Encephalitis, Viral
Interferon Beta Contributes to Astrocyte Activation in the Brain following Reovirus Infection.
Encephalomyelitis
In toxic demyelination oligodendroglial cell death occurs early and is FAS independent.
Encephalomyelitis
Selective inhibition of CCR2 expressing lymphomyeloid cells in experimental autoimmune encephalomyelitis by a GM-CSF-MCP1 fusokine.
Encephalomyelitis
Survivin prevents apoptosis by binding to caspase-3 in astrocytes infected with the BeAn strain of Theiler's murine encephalomyelitis virus.
Encephalomyelitis, Autoimmune, Experimental
In toxic demyelination oligodendroglial cell death occurs early and is FAS independent.
Encephalomyelitis, Autoimmune, Experimental
Selective inhibition of CCR2 expressing lymphomyeloid cells in experimental autoimmune encephalomyelitis by a GM-CSF-MCP1 fusokine.
Endolymphatic Hydrops
Activation of caspase-3 is associated with oxidative stress in the hydropic guinea pig cochlea.
Endometrial Hyperplasia
Apoptotic signaling pathways in uteri of rats with endometrial hyperplasia induced by ovariectomy combined with estrogen.
Endometrial Hyperplasia
Autophagy in ovary and polycystic ovary syndrome: role, dispute and future perspective.
Endometrial Hyperplasia
Deregulation of tissue homeostasis in endometria from patients with polycystic ovarian syndrome with and without endometrial hyperplasia.
Endometrial Hyperplasia
Fas-mediated pathway and apoptosis in normal, hyperplastic, and neoplastic endometrium.
Endometrial Hyperplasia
Melatonin reduced endometrial hyperplasia induced by estradiol in female albino rats.
Endometrial Neoplasms
?-bisabolol enhances radiotherapy-induced apoptosis in endometrial cancer cells by reducing the effect of XIAP on inhibiting caspase-3.
Endometrial Neoplasms
Cellular apoptosis susceptibility gene expression in endometrial carcinoma: correlation with Bcl-2, Bax, and caspase-3 expression and outcome.
Endometrial Neoplasms
Cleaved caspase-3 expression is a potential prognostic factor for endometrial cancer with positive peritoneal cytology.
Endometrial Neoplasms
Effects of 1alpha, 25-dihydroxyvitamin D3 on programmed cell death of Ishikawa endometrial cancer cells through ezrin phosphorylation.
Endometrial Neoplasms
Expression of Concern: ?-bisabolol enhances radiotherapy-induced apoptosis in endometrial cancer cells by reducing the effect of XIAP on inhibiting caspase-3.
Endometrial Neoplasms
Fas-mediated pathway and apoptosis in normal, hyperplastic, and neoplastic endometrium.
Endometrial Neoplasms
MLH1 enhances the sensitivity of human endometrial carcinoma cells to cisplatin by activating the MLH1/c-Abl apoptosis signaling pathway.
Endometrial Neoplasms
Polymorphisms and haplotypes in the caspase-3, caspase-7, and caspase-8 genes and risk for endometrial cancer: a population-based, case-control study in a Chinese population.
Endometrial Neoplasms
Progesterone inhibits growth and induces apoptosis in cancer cells through modulation of reactive oxygen species.
Endometrial Neoplasms
Receptorial and mitochondrial apoptotic pathways in normal and neoplastic human endometrium.
Endometrial Neoplasms
Ursolic acid induces Bax-dependent apoptosis through the caspase-3 pathway in endometrial cancer SNG-II cells.
Endometrial Neoplasms
USP14 is a predictor of recurrence in endometrial cancer and a molecular target for endometrial cancer treatment.
Endometrial Neoplasms
[Expression and relationship of Ezh2, Runx3 and caspase-3 in endometrial adenocarcinoma].
Endometriosis
Melatonin protects against endometriosis via regulation of matrix metalloproteinase-3 and an apoptotic pathway.
Endometriosis
[Expression of suppressor of cytokine signaling-3 and caspase-3 in endometriosis and their correlation].
Endometriosis
[The expression of Caspase-3 in granulosa cells of endometriosis treated with mifepristone].
Endotoxemia
Attenuation of ventilation-induced diaphragm dysfunction through toll-like receptor 4 and nuclear factor-?B in a murine endotoxemia model.
Endotoxemia
Effect of dexamethasone on nitric oxide synthase and Caspase-3 gene expressions in endotoxemia in neonate rat brain.
Endotoxemia
Endogenous interleukin 18 regulates testicular germ cell apoptosis during endotoxemia.
Endotoxemia
Inhibition of 3-Hydroxy-3-Methyl-Glutaryl-Coenzyme A Reductase Reduces Leukocyte Recruitment and Hepatocyte Apoptosis in Endotoxin-Induced Liver Injury.
Endotoxemia
Lipocalin 2 deficiency dysregulates iron homeostasis and exacerbates endotoxin-induced sepsis.
Endotoxemia
Pro-inflammatory cytokines, IL-1? and TNF-?, produce persistent compromise in tonic immobility defensive behaviour in endotoxemia guinea-pigs.
Endotoxemia
Protective effects of propofol on endotoxemia-induced acute kidney injury in rats.
Endotoxemia
Protein kinase C-dependent mitochondrial translocation of proapoptotic protein Bax on activation of inducible nitric-oxide synthase in rostral ventrolateral medulla mediates cardiovascular depression during experimental endotoxemia.
Endotoxemia
Suppression of Hypoxia-Inducible Factor 1? by Low-Molecular-Weight Heparin Mitigates Ventilation-Induced Diaphragm Dysfunction in a Murine Endotoxemia Model.
Enteritis
Gross Morphometry, Histomorphometry, and Immunohistochemistry Confirm Early and Persistent Jejunal Crypt Hyperplasia in Poults with Enteritis and Depressed Growth.
Enterocolitis, Necrotizing
Intestinal trefoil factor increased the Bcl-2 level in a necrotizingenterocolitis neonate rat model.
Enterocolitis, Necrotizing
[Regulatory effects of glutamine on Toll-like receptor 4 in neonatal rats with necrotizing enterocolitis].
Epidermal Cyst
Comparative Immunohistochemical Analyses on the Modes of Cell Death/Keratinization in Epidermal Cyst, Trichilemmal Cyst, and Pilomatricoma.
Epilepsy
Activation of CPP-32 protease in hippocampal neurons following ischemia and epilepsy.
Epilepsy
ADENOSINE A1 RECEPTOR AGONIST PROTECTS AGAINST HIPPOCAMPAL NEURONAL INJURY AFTER LITHIUM CHLORIDE-PILOCARPINE-INDUCED EPILEPSY.
Epilepsy
Administration of caspase 3 inhibitor during and after status epilepticus in rat: effect on neuronal damage and epileptogenesis.
Epilepsy
Anticonvulsant effect of piperine ameliorates memory impairment, inflammation and oxidative stress in a rat model of pilocarpine-induced epilepsy.
Epilepsy
Apoptotic Markers Are Increased in Epilepsy Patients: A Relation with Manganese Superoxide Dismutase Ala16Val Polymorphism and Seizure Type through IL-1? and IL-6 Pathways.
Epilepsy
Caspase-3 cleavage and nuclear localization of caspase-activated DNase in human temporal lobe epilepsy.
Epilepsy
Cortical expression of IL1-?, Bcl-2, Caspase-3 and 9, SEMA-3a, NT-3 and P-glycoprotein as biological markers of intrinsic severity in drug-resistant temporal lobe epilepsy.
Epilepsy
Depressive, inflammatory, and metabolic factors associated with cognitive impairment in patients with epilepsy.
Epilepsy
Differential regulation of apoptosis-related genes in resistant and vulnerable subfields of the rat epileptic hippocampus.
Epilepsy
Involvement of caspase-3-like protease in the mechanism of cell death following focally evoked limbic seizures.
Epilepsy
Neuronal apoptosis in the resected sclerotic hippocampus in patients with mesial temporal lobe epilepsy.
Epilepsy
New avenue in the treatment of temporal lobe epilepsy by classical anti-epileptics: A hypothetical establishment of executioner Caspase 3 inactivation by molecular modeling.
Epilepsy
Recombinant Human Erythropoietin Protects Myocardial Cells from Apoptosis via the Janus-Activated Kinase 2/Signal Transducer and Activator of Transcription 5 Pathway in Rats with Epilepsy.
Epilepsy
Targeting of microRNA-199a-5p protects against pilocarpine-induced status epilepticus and seizure damage via SIRT1-p53 cascade.
Epilepsy
The Effects of Topiramate on Caspase-3 Expression in Hippocampus of Basolateral Amygdala (BLA) Electrical Kindled Epilepsy Rat.
Epilepsy
[Apoptosis and expression of Caspase 3 and Caspase 4 in neurocytes of refractory human temporal lobe epilepsy].
Epilepsy, Absence
Elevated sterol regulatory elementary binding protein 1 and GluA2 levels in the hippocampal nuclear fraction of Genetic Absence Epilepsy Rats from Strasbourg.
Epilepsy, Generalized
Relationship between seizure type, metabolic profile, and inflammatory markers in blood samples of patients with epilepsy.
Epilepsy, Temporal Lobe
Caspase-3 cleavage and nuclear localization of caspase-activated DNase in human temporal lobe epilepsy.
Epilepsy, Temporal Lobe
Cortical expression of IL1-?, Bcl-2, Caspase-3 and 9, SEMA-3a, NT-3 and P-glycoprotein as biological markers of intrinsic severity in drug-resistant temporal lobe epilepsy.
Epilepsy, Temporal Lobe
Neuronal apoptosis in the resected sclerotic hippocampus in patients with mesial temporal lobe epilepsy.
Epilepsy, Temporal Lobe
New avenue in the treatment of temporal lobe epilepsy by classical anti-epileptics: A hypothetical establishment of executioner Caspase 3 inactivation by molecular modeling.
Epilepsy, Temporal Lobe
[Apoptosis and expression of Caspase 3 and Caspase 4 in neurocytes of refractory human temporal lobe epilepsy].
Erythema Multiforme
Apoptosis as a Mechanism for Keratinocyte Death in Canine Toxic Epidermal Necrolysis.
Escherichia coli Infections
Dietary genistein supplementation improves intestinal mucosal barrier function in Escherichia coli O78-challenged broilers.
Escherichia coli Infections
Hepatic histopathology and apoptosis in diet-induced-obese mice under Escherichia coli pneumonia.
Esophageal Achalasia
Expression of ki-67 antigen and caspase-3 protein in benign lesions and esophageal carcinoma.
Esophageal Neoplasms
Artesunate induces apoptosis and inhibits growth of Eca109 and Ec9706 human esophageal cancer cell lines in vitro and in vivo.
Esophageal Neoplasms
Costunolide Induces Apoptosis through Generation of ROS and Activation of P53 in Human Esophageal Cancer Eca-109 Cells.
Esophageal Neoplasms
Differentially expressed genes execute zinc-induced apoptosis in precancerous esophageal epithelium of zinc-deficient rats.
Esophageal Neoplasms
Indomethacin induces apoptosis in the EC109 esophageal cancer cell line by releasing second mitochondria-derived activator of caspase and activating caspase-3.
Esophageal Neoplasms
Knockdown of long non-coding RNA TP73-AS1 inhibits cell proliferation and induces apoptosis in esophageal squamous cell carcinoma.
Esophageal Neoplasms
Prognostic value of Caspase-3 expression in cancers of digestive tract: a meta-analysis and systematic review.
Esophageal Neoplasms
Pterostilbene Inhibits the Growth of Human Esophageal Cancer Cells by Regulating Endoplasmic Reticulum Stress.
Esophageal Neoplasms
Small proline-rich repeat protein 3 enhances the sensitivity of esophageal cancer cells in response to DNA damage-induced apoptosis.
Esophageal Neoplasms
Telomerase antagonist imetelstat increases radiation sensitivity in esophageal squamous cell carcinoma.
Esophageal Neoplasms
Upregulation of caspase-3 expression in esophageal cancer correlates with favorable prognosis: an immunohistochemical study from a high incidence area in northern China.
Esophageal Neoplasms
Value of long non-coding RNA Rpph1 in esophageal cancer and its effect on cancer cell sensitivity to radiotherapy.
Esophageal Neoplasms
[THAP11 mediates the proliferation and apoptosis of esophageal cancer cells via inhibiting ubiquitination of p53].
Esophageal Squamous Cell Carcinoma
Caspase-3 expression in metastatic lymph nodes of esophageal squamous cell carcinoma is prognostic of survival.
Esophageal Squamous Cell Carcinoma
Expression of Bax and apoptosis-related proteins in human esophageal squamous cell carcinoma including dysplasia.
Esophageal Squamous Cell Carcinoma
Genetic variant in CASP3 affects promoter activity and risk of esophageal squamous cell carcinoma.
Esophageal Squamous Cell Carcinoma
HOXC13 promotes proliferation of esophageal squamous cell carcinoma via repressing transcription of CASP3.
Esophageal Squamous Cell Carcinoma
Prognostic significance of caspase-3 expression in primary resected esophageal squamous cell carcinoma.
Esophageal Squamous Cell Carcinoma
Upregulation of caspase-3 expression in esophageal cancer correlates with favorable prognosis: an immunohistochemical study from a high incidence area in northern China.
Esophageal Squamous Cell Carcinoma
[CD-34 and CASPASE-3 biomarkers expression in esophageal epidermoid carcinoma]
Esophagitis
Expression of ki-67 antigen and caspase-3 protein in benign lesions and esophageal carcinoma.
Esophagitis
Expression of the bile acid receptor FXR in Barrett's esophagus and enhancement of apoptosis by guggulsterone in vitro.
Exanthema
Changes of Bcl-2, Bax and Caspase-3 expression in the dermal microvascular endothelial cells and the epidermal layers of the eschar (tache noire) in patients with Mediterranean spotted fever.
Eye Abnormalities
Azadirachtin acting as a hazardous compound to induce multiple detrimental effects in Drosophila melanogaster.
Facial Nerve Injuries
Acute Response of Neurons: An Early Event of Neuronal Cell Death After Facial Nerve Injury.
Facial Nerve Injuries
[Facial motoneurons death and caspase regulatory gene expression following facial nerve injury].
Familial Mediterranean Fever
Transcriptional activity of neutrophils exposed to high doses of colchicine: short communication.
Fanconi Anemia
Constitutive activation of caspase-3 and Poly ADP ribose polymerase cleavage in fanconi anemia cells.
Fanconi Anemia
Interferon-gamma-induced apoptotic responses of Fanconi anemia group C hematopoietic progenitor cells involve caspase 8-dependent activation of caspase 3 family members.
Fanconi Anemia
Loss of the Fanconi anemia group C protein activity results in an inability to activate caspase-3 after ionizing radiation.
Fanconi Anemia
The p38 pathway partially mediates caspase-3 activation induced by reactive oxygen species in Fanconi anemia C cells.
Farber Lipogranulomatosis
Involvement of caspase-3 and GD3 ganglioside in ceramide-induced apoptosis in Farber disease.
Fatty Liver
Effects of a high-fiber diet on hepatocyte apoptosis and liver regeneration after partial hepatectomy in rats with fatty liver.
Fatty Liver
Fatty liver vulnerability to endotoxin-induced damage despite NF-kappaB induction and inhibited caspase 3 activation.
Fatty Liver
Levels of Hepatic Activating Transcription Factor 6 and Caspase-3 Are Downregulated in Mice after Excessive Training.
Fatty Liver
Mitochondrial antiviral signaling protein defect links impaired antiviral response and liver injury in steatohepatitis in mice.
Fatty Liver
Role of CHOP in hepatic apoptosis in the murine model of intragastric ethanol feeding.
Fatty Liver
[Intensity of apoptotic processes, aconitate hydratase activity and citrate level in patients with type 2 diabetes mellitus complicated steatohepatitis under application of epifamin at basic therapy].
Fatty Liver, Alcoholic
Molecular pathology and clinical aspects of alcohol-induced tissue injury.
Fatty Liver, Alcoholic
Use of cultured cells in assessing ethanol toxicity and ethanol-related metabolism.
Fetal Alcohol Spectrum Disorders
Nicotinamide Inhibits Ethanol-Induced Caspase-3 and PARP-1 Over-activation and Subsequent Neurodegeneration in the Developing Mouse Cerebellum.
Fetal Alcohol Spectrum Disorders
Tau phosphorylation and cleavage in ethanol-induced neurodegeneration in the developing mouse brain.
Fetal Diseases
Apoptosis and its pathway in early post-implantation embryos of diabetic rats.
Fetal Growth Retardation
Expression of caspase-3, Bax nad Bcl-2 in placentas from pregnancies complicated by treated and non-treated fetal growth restriction.
Fetal Growth Retardation
Expression of nuclear factor-kappa B and placental apoptosis in pregnancies complicated with intrauterine growth restriction and preeclampsia: an immunohistochemical study.
Fetal Growth Retardation
Placental apoptosis in preeclampsia, intrauterine growth retardation, and HELLP syndrome: an immunohistochemical study with caspase-3 and bcl-2.
Fetal Growth Retardation
[Effect of magnesium sulfate on fetal rats of fetal growth retardation and its relation with expression of caspase-3 on the placenta of maternal rat]
Fetal Hypoxia
Uteroplacental insufficiency lowers the threshold towards hypoxia-induced cerebral apoptosis in growth-retarded fetal rats.
Fibromatosis, Aggressive
Aggressive fibromatosis (desmoid tumor) is derived from mesenchymal progenitor cells.
Fibrosarcoma
AKAP12 induces apoptotic cell death in human fibrosarcoma cells by regulating CDKI-cyclin D1 and caspase-3 activity.
Fibrosarcoma
Glucocorticoids inhibit apoptosis during fibrosarcoma development by transcriptionally activating Bcl-xL.
Fibrosarcoma
Nano-Pulse Stimulation is a physical modality that can trigger immunogenic tumor cell death.
Fibrosarcoma
Stabilization and translocation of p53 to mitochondria is linked to Bax translocation to mitochondria in simvastatin-induced apoptosis.
Fibrosarcoma
The antiproliferative function of violacein-like purple violet pigment (PVP) from an Antarctic Janthinobacterium sp. Ant5-2 in UV-induced 2237 fibrosarcoma.
Fibrosarcoma
The histone deacetylase inhibitor vorinostat selectively sensitizes fibrosarcoma cells to chemotherapy.
Fibrosarcoma
[?-aminobutyric acid fortified rice alleviated oxidative stress and pancreatic injury in type 2 diabetic mice].
Folic Acid Deficiency
Maternal folic acid deficiency stimulates neural cell apoptosis via miR-34a associated with Bcl-2 in the rat foetal brain.
Follicular Cyst
Chronic effects of maternal tobacco-smoke exposure and/or ?-lipoic acid treatment on reproductive parameters in female rat offspring.
Follicular Cyst
Sex steroid receptors and apoptosis-related proteins are differentially expressed in polycystic ovaries of adult dogs.
Foot-and-Mouth Disease
Caspases are not involved in the cleavage of translation initiation factor eIF4GI during picornavirus infection.
Frontotemporal Dementia
DNA damage and activated caspase-3 expression in neurons and astrocytes: evidence for apoptosis in frontotemporal dementia.
Frontotemporal Dementia
Retinoic acid worsens ATG10-dependent autophagy impairment in TBK1-mutant hiPSC-derived motoneurons through SQSTM1/p62 accumulation.
Frontotemporal Lobar Degeneration
PTK2/FAK regulates UPS impairment via SQSTM1/p62 phosphorylation in TARDBP/TDP-43 proteinopathies.
Gallbladder Neoplasms
Elucidation of the chemopreventive role of stigmasterol against Jab1 in Gall bladder carcinoma.
Gallbladder Neoplasms
Triptolide induces s phase arrest and apoptosis in gallbladder cancer cells.
Ganglion Cysts
Neuroprotective effects of (-)-epigallocatechin-3-gallate (EGCG) against peripheral nerve transection-induced apoptosis.
Ganglion Cysts
Neuroprotective effects of hyperbaric oxygen (HBO) therapy on neuronal death induced by sciatic nerve transection in rat.
Ganglion Cysts
Rutin ameliorates diabetic neuropathy by lowering plasma glucose and decreasing oxidative stress via Nrf2 signaling pathway in rats.
Gastritis
Apoptosis in different gastric lesions and gastric cancer: relationship with Helicobacter pylori, overexpression of p53 and aneuploidy.
Gastritis
Differential caspase-3 expression in noncancerous, premalignant and cancer tissues of stomach and its clinical implication.
Gastritis
Effect of ebrotidine on gastric mucosal inflammatory responses to Helicobacter pylori lipopolysaccharide.
Gastritis
Gastric mucosal inflammatory responses to Helicobacter pylori lipopolysaccharide: down-regulation of nitric oxide synthase-2 and caspase-3 by sulglycotide.
Gastritis
Gastric mucosal inflammatory responses toHelicobacter pylori lipopolysaccharide: Suppression of caspase-3 and nitric oxide synthase-2 by omeprazole and sucralfate.
Gastritis
Induction of caspase-3 and nitric oxide synthase-2 during gastric mucosal inflammatory reaction to Helicobacter pylori lipopolysaccharide.
Gastritis
Influence of COX-2 inhibition by rofecoxib on serum and tumor progastrin and gastrin levels and expression of PPARgamma and apoptosis-related proteins in gastric cancer patients.
Gastritis, Atrophic
Apoptosis in different gastric lesions and gastric cancer: relationship with Helicobacter pylori, overexpression of p53 and aneuploidy.
Gastritis, Atrophic
[Down-regulation of Caspase-3 expression in precancerous lesions and its relation to gastric carcinogenesis]
Gastrointestinal Neoplasms
Prognostic value of Caspase-3 expression in cancers of digestive tract: a meta-analysis and systematic review.
Gestational Trophoblastic Disease
Apoptotic index for prediction of postmolar gestational trophoblastic neoplasia.
Giant Cell Tumors
Bisphosphonates may reduce recurrence in giant cell tumor by inducing apoptosis.
Gingival Overgrowth
Apoptosis and expression of caspase-3 in cyclosporin-induced gingival overgrowth.
Gingival Overgrowth
Reduction in lipopolysaccharide-induced apoptosis of fibroblasts obtained from a patient with gingival overgrowth during nifedipine-treatment.
Gingival Overgrowth
[Apoptosis and expression of Bcl-2 and caspase-3 in ciclosporin-induced gingival overgrowth of rats].
Gingivitis
Expression of key executioner of apoptosis caspase-3 in periodontal health and disease.
Glaucoma
Alpha-fodrin is cleaved by caspase-3 in a chronic ocular hypertensive (COH) rat model of glaucoma.
Glaucoma
Ganglion cells apoptosis in diabetic rats as early prediction of glaucoma: a study of Brn3b gene expression and association with change of quantity of NO, caspase-3, NF-?B, and TNF-?.
Glaucoma
microRNA-21a-5p/PDCD4 axis regulates mesenchymal stem cell-induced neuroprotection in acute glaucoma.
Glaucoma
The effects of intravitreal H2 S application on apoptosis in the retina and cornea in experimental glaucoma model.
Glaucoma, Open-Angle
Ganglion cells apoptosis in diabetic rats as early prediction of glaucoma: a study of Brn3b gene expression and association with change of quantity of NO, caspase-3, NF-?B, and TNF-?.
Glioblastoma
'Dendrimer-Cationized-Albumin' encrusted polymeric nanoparticle improves BBB penetration and anticancer activity of doxorubicin.
Glioblastoma
1'-Acetoxychavicol acetate promotes caspase 3-activated glioblastoma cell death by overcoming enhanced cytokine expression.
Glioblastoma
A constitutively active form of neurokinin 1 receptor and neurokinin 1 receptor-mediated apoptosis in glioblastomas.
Glioblastoma
A novel nanocomposite based on fluorescent turn-on gold nanostars for near-infrared photothermal therapy and self-theranostic caspase-3 imaging of glioblastoma tumor cell.
Glioblastoma
A novel small molecule inhibits STAT3 phosphorylation and DNA binding activity and exhibits potent growth suppressive activity in human cancer cells.
Glioblastoma
A novel small molecule, LLL12, inhibits STAT3 phosphorylation and activities and exhibits potent growth-suppressive activity in human cancer cells.
Glioblastoma
Aclidinium bromide inhibits proliferation, migration and invasion but promotes apoptosis of human glioma cells via PI3K/AKT signaling pathway.
Glioblastoma
ADAM-10 could mediate cleavage of N-cadherin promoting apoptosis in human atherosclerotic lesions leading to vulnerable plaque: A morphological and immunohistochemical study.
Glioblastoma
AKT2-knockdown suppressed viability with enhanced apoptosis, and attenuated chemoresistance to temozolomide of human glioblastoma cells in vitro and in vivo.
Glioblastoma
Antioxidant vitamins promote anticancer effects on low-concentration methotrexate-treated glioblastoma cells via enhancing the caspase-3 death pathway.
Glioblastoma
Association between SET expression and glioblastoma cell apoptosis and proliferation.
Glioblastoma
B4GalT1 Regulates Apoptosis and Autophagy of Glioblastoma In Vitro and In Vivo.
Glioblastoma
Bcl2L12-mediated inhibition of effector caspase-3 and caspase-7 via distinct mechanisms in glioblastoma.
Glioblastoma
Caffeine inhibits the growth of glioblastomas through activating the caspase-3 signaling pathway in vitro.
Glioblastoma
Cannabidiol inhibits human glioma by induction of lethal mitophagy through activating TRPV4.
Glioblastoma
Celastrol targets proteostasis and acts synergistically with a heat-shock protein 90 inhibitor to kill human glioblastoma cells.
Glioblastoma
Cell death in amyotrophic lateral sclerosis: interplay between neuronal and glial cells.
Glioblastoma
CHOP and caspase 3 induction underlie glioblastoma cell death in response to endoplasmic reticulum stress.
Glioblastoma
Co-localization of PCNA, VCAM-1 and caspase-3 with nestin in xenografts derived from human anaplastic astrocytoma and glioblastoma multiforme tumor spheres.
Glioblastoma
Coibamide A induces mTOR-independent autophagy and cell death in human glioblastoma cells.
Glioblastoma
Correction of aberrant FGFR1 alternative RNA splicing through targeting of intronic regulatory elements.
Glioblastoma
CRM197 in Combination With shRNA Interference of VCAM-1 Displays Enhanced Inhibitory Effects on Human Glioblastoma Cells.
Glioblastoma
Cycling hypoxia induces chemoresistance through the activation of reactive oxygen species-mediated B-cell lymphoma extra-long pathway in glioblastoma multiforme.
Glioblastoma
Cyclopamine sensitizes glioblastoma cells to temozolomide treatment through Sonic hedgehog pathway.
Glioblastoma
Differential PARP cleavage: an indication for existence of multiple forms of cell death in human gliomas.
Glioblastoma
Differential response of human glioblastoma cell lines to combined camptothecin and ionizing radiation treatment.
Glioblastoma
Differential roles of Bcl2L12 and its short variant in breast cancer lymph node metastasis.
Glioblastoma
Down-regulation of Bcl-2 and Bcl-xL expression with bispecific antisense treatment in glioblastoma cell lines induce cell death.
Glioblastoma
Downregulation of Apaf-1 and caspase-3 by RNA interference in human glioma cells: consequences for erucylphosphocholine-induced apoptosis.
Glioblastoma
Exploring new applications of tulip tree (Liriodendron tulipifera L.): leaf essential oil as apoptotic agent for human glioblastoma.
Glioblastoma
Expression of long intergenic non-coding RNA, regulator of reprogramming, and its prognostic value in patients with glioblastoma.
Glioblastoma
Fas, FasL, and cleaved caspases 8 and 3 in glioblastomas: A tissue microarray-based study.
Glioblastoma
High expression of XIAP and Bcl-2 may inhibit programmed cell death in glioblastomas.
Glioblastoma
High-level Sp1 is Associated with Proliferation, Invasion, and Poor Prognosis in Astrocytoma.
Glioblastoma
Immunocytochemical detection of members of the caspase cascade of apoptosis in high-grade astrocytomas.
Glioblastoma
Immunohistochemical localization of caspase-3, caspase-9 and Bax in U87 glioblastoma xenografts.
Glioblastoma
In vivo imaging of early stage apoptosis by measuring real-time caspase-3/7 activation.
Glioblastoma
Induction of Mitochondrial Dysfunction and Oxidative Damage by Antibiotic Drug Doxycycline Enhances the Responsiveness of Glioblastoma to Chemotherapy.
Glioblastoma
Inhibition of glioma growth by flavokawain B is mediated through endoplasmic reticulum stress induced autophagy.
Glioblastoma
Knockdown of NUPR1 inhibits the proliferation of glioblastoma cells via ERK1/2, p38 MAPK and caspase-3.
Glioblastoma
LLL-3 inhibits STAT3 activity, suppresses glioblastoma cell growth and prolongs survival in a mouse glioblastoma model.
Glioblastoma
Major Contribution of Caspase-9 to Honokiol-Induced Apoptotic Insults to Human Drug-Resistant Glioblastoma Cells.
Glioblastoma
Measurement of tamoxifen-induced apoptosis in glioblastoma by cytometric bead analysis of active caspase-3.
Glioblastoma
MicroRNA-640 promotes cell proliferation and adhesion in glioblastoma by targeting Slit guidance ligand 1.
Glioblastoma
MiR-21 protected human glioblastoma U87MG cells from chemotherapeutic drug temozolomide induced apoptosis by decreasing Bax/Bcl-2 ratio and caspase-3 activity.
Glioblastoma
Molecular evidence of apoptotic death in malignant brain tumors including glioblastoma multiforme: upregulation of calpain and caspase-3.
Glioblastoma
N-(4-Hydroxyphenyl)retinamide induced differentiation with repression of telomerase and cell cycle to increase interferon-gamma sensitivity for apoptosis in human glioblastoma cells.
Glioblastoma
Notch-1 activation-dependent p53 restoration contributes to resveratrol-induced apoptosis in glioblastoma cells.
Glioblastoma
Novel anti-apoptotic microRNAs 582-5p and 363 promote human glioblastoma stem cell survival via direct inhibition of caspase 3, caspase 9, and Bim.
Glioblastoma
Phosphatidylinositol 3-Kinase/AKT Pathway Inhibition by Doxazosin Promotes Glioblastoma Cells Death, Upregulation of p53 and Triggers Low Neurotoxicity.
Glioblastoma
Protein kinase C-eta regulates resistance to UV- and gamma-irradiation-induced apoptosis in glioblastoma cells by preventing caspase-9 activation.
Glioblastoma
Puerarin inhibits proliferation and induces apoptosis in human glioblastoma cell lines.
Glioblastoma
Quercetin Increases the Efficacy of Glioblastoma Treatment Compared to Standard Chemoradiotherapy by the Suppression of PI-3-Kinase-Akt Pathway.
Glioblastoma
Resveratrol and siRNA in combination reduces Hsp27 expression and induces caspase-3 activity in human glioblastoma cells.
Glioblastoma
Silibinin Induced Human Glioblastoma Cell Apoptosis Concomitant with Autophagy through Simultaneous Inhibition of mTOR and YAP.
Glioblastoma
ST-11: A New Brain-Penetrant Microtubule-Destabilizing Agent with Therapeutic Potential for Glioblastoma Multiforme.
Glioblastoma
Survivin expression in glioblastomas correlates with proliferation, but not with apoptosis.
Glioblastoma
Survivin, caspase-3 and MIB-1 expression in astrocytic tumors of various grades.
Glioblastoma
Synthetic chenodeoxycholic acid derivatives inhibit glioblastoma multiform tumor growth in vitro and in vivo.
Glioblastoma
The inhibitor of growth 1 (ING1) is involved in trichostatin A-induced apoptosis and caspase 3 signaling in p53-deficient glioblastoma cells.
Glioblastoma
The Interruption of PKC-? Signaling and TRAIL Combination Therapy Against Glioblastoma Cells.
Glioblastoma
Therapeutic Effect of IL-4 Receptor-Targeting Pro-Apoptotic Peptide (AP1-ELP-KLAK) in Glioblastoma Tumor Model.
Glioblastoma
Tivantinib Hampers the Proliferation of Glioblastoma Cells via PI3K/Akt/Mammalian Target of Rapamycin (mTOR) Signaling.
Glioblastoma
Up-regulation of micro-RNA-221 (miRNA-221; chr Xp11.3) and caspase-3 accompanies down-regulation of the survivin-1 homolog BIRC1 (NAIP) in glioblastoma multiforme (GBM).
Glioblastoma
Urokinase plasminogen activator receptor and/or matrix metalloproteinase-9 inhibition induces apoptosis signaling through lipid rafts in glioblastoma xenograft cells.
Glioblastoma
Verbascoside Inhibits Glioblastoma Cell Proliferation, Migration and Invasion While Promoting Apoptosis Through Upregulation of Protein Tyrosine Phosphatase SHP-1 and Inhibition of STAT3 Phosphorylation.
Glioblastoma
VRK1 Depletion Facilitates the Synthetic Lethality of Temozolomide and Olaparib in Glioblastoma Cells.
Glioma
2'-Hydroxy C16-Ceramide Induces Apoptosis-Associated Proteomic Changes in C6 Glioma Cells.
Glioma
?-Carboline derivative TJY-16 inhibits tumor growth by inducing G2/M cell cycle arrest in glioma cells.
Glioma
Activation of c-Jun N-terminal kinase 1 and caspase 3 in the tamoxifen-induced apoptosis of rat glioma cells.
Glioma
Adenovirus-mediated transfer of caspase-3 with Fas ligand induces drastic apoptosis in U-373MG glioma cells.
Glioma
Adipocyte enhancer binding protein 1 (AEBP1) knockdown suppresses human glioma cell proliferation, invasion and induces early apoptosis.
Glioma
Arachidonic acid converts the glutathione depletion-induced apoptosis to necrosis by promoting lipid peroxidation and reducing caspase-3 activity in rat glioma cells.
Glioma
Arctigenin, a natural lignan compound, induces G0/G1 cell cycle arrest and apoptosis in human glioma cells.
Glioma
Arsenic trioxide sensitizes human glioma cells, but not normal astrocytes, to TRAIL-induced apoptosis via CCAAT/enhancer-binding protein homologous protein-dependent DR5 up-regulation.
Glioma
AS602801 sensitizes glioma cells to temozolomide and vincristine by blocking gap junction communication between glioma cells and astrocytes.
Glioma
Autophagy involvement in olanzapine-mediated cytotoxic effects in human glioma cells.
Glioma
Bax and Bid act in synergy to bring about T11TS-mediated glioma apoptosis via the release of mitochondrial cytochrome c and subsequent caspase activation.
Glioma
Bcl2L12-mediated inhibition of effector caspase-3 and caspase-7 via distinct mechanisms in glioblastoma.
Glioma
Betulinic acid derivative B10 inhibits glioma cell proliferation through suppression of SIRT1, acetylation of FOXO3a and upregulation of Bim/PUMA.
Glioma
Bicyclic triterpenoid Iripallidal induces apoptosis and inhibits Akt/mTOR pathway in glioma cells.
Glioma
Borneol promotes apoptosis of Human Glioma Cells through regulating HIF-1a expression via mTORC1/eIF4E pathway.
Glioma
Cannabidiol inhibits human glioma by induction of lethal mitophagy through activating TRPV4.
Glioma
Caspase 3 gene expression and [Ca2+]i homeostasis underlying desipramine-induced C6 glioma cell apoptosis.
Glioma
CDK4/6 inhibition suppresses tumour growth and enhances the effect of temozolomide in glioma cells.
Glioma
Celastrol enhances TRAIL-induced apoptosis in human glioblastoma via the death receptor pathway.
Glioma
Centrosomal Protein of 55 Regulates Glucose Metabolism, Proliferation and Apoptosis of Glioma Cells via the Akt/mTOR Signaling Pathway.
Glioma
Chemotherapy primes malignant glioma cells for CD95 ligand-induced apoptosis up-stream of caspase 3 activation.
Glioma
Chlorotoxin fusion protein regulates miR-374a and TNFAIP8 expression and inhibits glioma cell proliferation and promotes apoptosis.
Glioma
Conditioned media from human adipose tissue-derived mesenchymal stem cells and umbilical cord-derived mesenchymal stem cells efficiently induced the apoptosis and differentiation in human glioma cell lines in vitro.
Glioma
Cord blood stem cell-mediated induction of apoptosis in glioma downregulates X-linked inhibitor of apoptosis protein (XIAP).
Glioma
Crm-A, bcl-2 and NDGA inhibit CD95L-induced apoptosis of malignant glioma cells at the level of caspase 8 processing.
Glioma
Delayed growth of glioma by a polysaccharide from Aster tataricus involve upregulation of Bax/Bcl-2 ratio, activation of caspase-3/8/9, and downregulation of the Akt.
Glioma
Desipramine induces apoptosis in rat glioma cells via endoplasmic reticulum stress-dependent CHOP pathway.
Glioma
Differential induction of apoptosis by antidepressants in glioma and neuroblastoma cell lines: evidence for p-c-Jun, cytochrome c, and caspase-3 involvement.
Glioma
Differential pro-apoptotic effects of synthetic 4-thiazolidinone derivative Les-3288, doxorubicin and temozolomide in human glioma U251 cells.
Glioma
Dihydroartemisinin exhibits anti-glioma stem cell activity through inhibiting p-AKT and activating caspase-3.
Glioma
Distribution of activated caspase-3 in relation with apoptosis in human malignant gliomas.
Glioma
Downregulation of Apaf-1 and caspase-3 by RNA interference in human glioma cells: consequences for erucylphosphocholine-induced apoptosis.
Glioma
Dying glioma cells establish a proangiogenic microenvironment through a caspase 3 dependent mechanism.
Glioma
Effect of ?, ? momorcharin on viability, caspase activity, cytochrome c release and on cytosolic calcium levels in different cancer cell lines.
Glioma
Effects of platycodin D on proliferation, apoptosis and PI3K/Akt signal pathway of human glioma U251 cells.
Glioma
Elevated expression of Dickkopf-1 increases the sensitivity of human glioma cell line SHG44 to BCNU.
Glioma
Enhanced apoptosis following treatment with TRA-8 anti-human DR5 monoclonal antibody and overexpression of exogenous Bax in human glioma cells.
Glioma
Evaluation of Combination Treatment Effect With TRAIL-secreting Mesenchymal Stem Cells and Compound C Against Glioblastoma.
Glioma
Evaluation of Cytotoxic Activity of Betanin Against U87MG Human Glioma Cells and Normal Human Lymphocytes and Its Anticancer Potential Through Mitochondrial Pathway.
Glioma
Evaluation of therapeutic effects of natural killer (NK) cell-based immunotherapy in mice using in vivo apoptosis bioimaging with a caspase-3 sensor.
Glioma
Evodiamine Prevents Glioma Growth, Induces Glioblastoma Cell Apoptosis and Cell Cycle Arrest through JNK Activation.
Glioma
Expression of the tumor necrosis factor receptor-associated factors 1 and 2 and regulation of the nuclear factor-kappaB antiapoptotic activity in human gliomas.
Glioma
Extract from mistletoe, Viscum album L., reduces Hsp27 and 14-3-3 protein expression and induces apoptosis in C6 rat glioma cells.
Glioma
Gene therapy using an adenovirus vector for apoptosis-related genes is a highly effective therapeutic modality for killing glioma cells.
Glioma
Glial-specific retrovirally mediated gas1 gene expression induces glioma cell apoptosis and inhibits tumor growth in vivo.
Glioma
Glioma-induced inhibition of caspase-3 in microglia promotes a tumor-supportive phenotype.
Glioma
Growth Inhibition and Induction of Apoptosis in SHG-44 Glioma Cells by Chinese Medicine Formula "Pingliu Keli".
Glioma
Honokiol induces autophagic cell death in malignant glioma through reactive oxygen species-mediated regulation of the p53/PI3K/Akt/mTOR signaling pathway.
Glioma
Human amniotic membrane derived-mesenchymal stem cells induce C6 glioma apoptosis in vivo through the Bcl-2/caspase pathways.
Glioma
Hydrogel matrix entrapping PLGA-paclitaxel microspheres: drug delivery with near zero-order release and implantability advantages for malignant brain tumour chemotherapy.
Glioma
Improved effects of honokiol on temozolomide-induced autophagy and apoptosis of drug-sensitive and -tolerant glioma cells.
Glioma
Induction of apoptosis by in vitro and in vivo plant extracts derived from Menyanthes trifoliata L. in human cancer cells.
Glioma
Induction of apoptosis in glioma cells by molecules released from activated macrophages.
Glioma
Inhibitory effect of DNA topoisomerase inhibitor isoliquiritigenin on the growth of glioma cells.
Glioma
Insulin-like growth factor-I decreased etoposide-induced apoptosis in glioma cells by increasing bcl-2 expression and decreasing CPP32 activity.
Glioma
Integrin ?V?3 silencing sensitizes malignant glioma cells to temozolomide by suppression of homologous recombination repair.
Glioma
Interference of ursolic acid treatment with glioma growth: An in vitro and in vivo study.
Glioma
Investigation of platinum nanoparticle properties against U87 glioblastoma multiforme.
Glioma
Irradiation induced clonogenic cell death of human malignant glioma cells does not require CD95/CD95L interactions.
Glioma
Linarin suppresses glioma through inhibition of NF-?B/p65 and up-regulating p53 expression in vitro and in vivo.
Glioma
LINC01158 works as an oncogene in glioma via sponging miR-6734-3p to boost CENPK expression.
Glioma
LncRNA LINC00689 Promotes the Tumorigenesis of Glioma via Mediation of miR-526b-3p/IGF2BP1 Axis.
Glioma
lncRNA SNHG16 Exerts Oncogenic Functions in Promoting Proliferation of Glioma Through Suppressing p21.
Glioma
Low frequency and intensity ultrasound induces apoptosis of brain glioma in rats mediated by caspase-3, Bcl-2, and survivin.
Glioma
Lower expression of Nrdp1 in human glioma contributes tumor progression by reducing apoptosis.
Glioma
LPA1 mediates antidepressant-induced ERK1/2 signalling and protection from oxidative stress in glial cells.
Glioma
Mangiferin regulates proliferation and apoptosis in glioma cells by induction of microRNA-15b and inhibition of MMP-9 expression.
Glioma
MicroRNA 10a induces glioma tumorigenesis by targeting myotubularin-related protein 3 and regulating the Wnt/?-catenin signaling pathway.
Glioma
MicroRNA-142-3p inhibits proliferation and induces apoptosis by targeting the high-mobility group box 1 via the Wnt/?-catenin signaling pathway in glioma.
Glioma
MicroRNA-21 promotes glioma cell proliferation and inhibits senescence and apoptosis by targeting SPRY1 via the PTEN/PI3K/AKT signaling pathway.
Glioma
MicroRNA-320 Enhances Radiosensitivity of Glioma Through Down-Regulation of Sirtuin Type 1 by Directly Targeting Forkhead Box Protein M1.
Glioma
MiR-135a and MRP1 play pivotal roles in the selective lethality of phenethyl isothiocyanate to malignant glioma cells.
Glioma
mTOR, S6 and AKT expression in relation to proliferation and apoptosis/autophagy in glioma.
Glioma
Multifunctional nanocarrier mediated co-delivery of doxorubicin and siRNA for synergistic enhancement of glioma apoptosis in rat.
Glioma
Nanocrystallized Oleanolic Acid Better Inhibits Proliferation, Migration and Invasion in Intracranial Glioma via Caspase-3 Pathway.
Glioma
Noninvasive imaging of apoptosis induced by adenovirus-mediated cancer gene therapy using a caspase-3 biosensor in living subjects.
Glioma
NVP-BEZ235, a novel dual PI3K-mTOR inhibitor displays anti-glioma activity and reduces chemoresistance to temozolomide in human glioma cells.
Glioma
Oncoprotein Bmi-1 renders apoptotic resistance to glioma cells through activation of the IKK-nuclear factor-kappaB Pathway.
Glioma
Oroxyloside inhibits human glioma progression by suppressing proliferation, metastasis and inducing apoptosis related pathways.
Glioma
Overexpression of transient receptor potential mucolipin-2 ion channels in gliomas: role in tumor growth and progression.
Glioma
p53 enhances BAK and CD95 expression in human malignant glioma cells but does not enhance CD95L-induced apoptosis.
Glioma
Paxilline enhances TRAIL-mediated apoptosis of glioma cells via modulation of c-FLIP, survivin and DR5.
Glioma
PEG2000-DPSE-coated quercetin nanoparticles remarkably enhanced anticancer effects through induced programed cell death on C6 glioma cells.
Glioma
Persian Gulf Snail Crude Venom (Conus textile): A Potential Source of Anti-Cancer Therapeutic Agents for Glioblastoma through Mitochondrial-Mediated Apoptosis.
Glioma
Pharmacological Improvement and Preclinical Evaluation of Methotrexate-Loaded Lipid-Core Nanocapsules in a Glioblastoma Model.
Glioma
Pisosterol Induces G2/M Cell Cycle Arrest and Apoptosis via the ATM/ATR Signaling Pathway in Human Glioma Cells.
Glioma
Polyphyllin D induces apoptosis in U87 human glioma cells through the c-Jun NH2-terminal kinase pathway.
Glioma
Pre-treatment or Post-treatment of Human Glioma Cells With BIX01294, the Inhibitor of Histone Methyltransferase G9a, Sensitizes Cells to Temozolomide.
Glioma
Prevention of irradiation-induced glioma cell invasion by temozolomide involves caspase 3 activity and cleavage of focal adhesion kinase.
Glioma
Prognostic significance of the immunohistochemical staining of cleaved caspase-3, an activated form of caspase-3, in gliomas.
Glioma
Proteasome inhibition with bortezomib induces cell death in GBM stem-like cells and temozolomide-resistant glioma cell lines, but stimulates GBM stem-like cells' VEGF production and angiogenesis.
Glioma
Protein delivery of caspase-3 induces cell death in malignant C6 glioma, primary astrocytes and immortalized and primary brain capillary endothelial cells.
Glioma
Prucalopride inhibits the glioma cells proliferation and induces autophagy via AKT-mTOR pathway.
Glioma
PSMB8 regulates glioma cell migration, proliferation, and apoptosis through modulating ERK1/2 and PI3K/AKT signaling pathways.
Glioma
Quercetin derivative induces cell death in glioma cells by modulating NF-?B nuclear translocation and caspase-3 activation.
Glioma
Radio-responsive gene therapy for malignant glioma cells without the radiosensitive promoter: Caspase-3 gene therapy combined with radiation.
Glioma
Regression of glioma tumor growth in F98 and U87 rat glioma models by the Nitrone OKN-007.
Glioma
Roscovitine effectively enhances antitumor activity of temozolomide in vitro and in vivo mediated by increased autophagy and Caspase-3 dependent apoptosis.
Glioma
Rosmarinic acid and siRNA combined therapy represses Hsp27 (HSPB1) expression and induces apoptosis in human glioma cells.
Glioma
Sauchinone, a lignan from Saururus chinensis, inhibits staurosporine-induced apoptosis in C6 rat glioma cells.
Glioma
Shikonin induces tumor apoptosis in glioma cells via endoplasmic reticulum stress, and Bax/Bak mediated mitochondrial outer membrane permeability.
Glioma
Shuttling SLC2A4RG is regulated by 14-3-3? to modulate cell survival via caspase-3 and caspase-6 in human glioma.
Glioma
Simultaneous Interference with HER1/EGFR and RAC1 Signaling Drives Cytostasis and Suppression of Survivin in Human Glioma Cells in Vitro.
Glioma
Sulindac sulfide inhibits sarcoendoplasmic reticulum Ca2+ ATPase, induces endoplasmic reticulum stress response, and exerts toxicity in glioma cells: relevant similarities to and important differences from celecoxib.
Glioma
Synthesis and in vitro evaluation of 4-substituted furano[3,2-c] tetrahydroquinolines as potential anti-cancer agents.
Glioma
Targeting 14-3-3 protein, difopein induces apoptosis of human glioma cells and suppresses tumor growth in mice.
Glioma
The excitatory amino acid transporter-2 induces apoptosis and decreases glioma growth in vitro and in vivo.
Glioma
The inhibitory effects of ginsenoside Rd on the human glioma U251 cells and its underlying mechanisms.
Glioma
The nuclear transporter importin-11 regulates the Wnt/?-catenin pathway and acts as a tumor promoter in glioma.
Glioma
Transcriptionally mediated gene targeting of gas1 to glioma cells elicits growth arrest and apoptosis.
Glioma
Transformed Root Extract of Leonurus sibiricus Induces Apoptosis through Intrinsic and Extrinsic Pathways in Various Grades of Human Glioma Cells.
Glioma
TRIM44 is indispensable for glioma cell proliferation and cell cycle progression through AKT/p21/p27 signaling pathway.
Glioma
UMI-77 primes glioma cells for TRAIL-induced apoptosis by unsequestering Bim and Bak from Mcl-1.
Glioma
Wild-type p53-dependent etoposide-induced apoptosis mediated by caspase-3 activation in human glioma cells.
Glioma
Xanthatin induces glioma cell apoptosis and inhibits tumor growth via activating endoplasmic reticulum stress-dependent CHOP pathway.
Glioma
[Suppressive effect of resveratrol on growth of U251 human glioma cells and its correlated mechanism]
Glioma
[Toxic effects of Vitamin C combined with temozolomide on glioma cells and its mechanism].
Glomerulonephritis
A shift in the Bax/Bcl-2 balance may activate caspase-3 and modulate apoptosis in experimental glomerulonephritis.
Glomerulonephritis
Apoptosis and caspase-3 in experimental anti-glomerular basement membrane nephritis.
Glomerulonephritis
Suppression of apoptosis by glucocorticoids in glomerular endothelial cells: effects on proapoptotic pathways.
Glomerulonephritis, Membranous
[Expression of Caspase-3 increased in children with hepatitis B virus-associated membranous nephropathy]
Glucose Intolerance
Adiponectin reduces ER stress-induced apoptosis through PPAR? transcriptional regulation of ATF2 in mouse adipose.
Glucose Intolerance
[Effect of liraglutide on interleukin-1? expression in the pancreatic islets of OLETF rats].
Glycosuria
Syzygium jambos extract mitigates pancreatic oxidative stress, inflammation and apoptosis and modulates hepatic IRS-2/AKT/GLUT4 signaling pathway in streptozotocin-induced diabetic rats.
Goiter
Cytophotometric expression of Caspase-3 in papillary thyroid carcinoma in nodular goiter colloid.
Goiter, Nodular
Cytophotometric expression of Caspase-3 in papillary thyroid carcinoma in nodular goiter colloid.
Graft vs Host Disease
Detection of apoptoses in gastro-intestinal graft-versus-host disease and cytomegalovirus colitis by a commercially available antibody against caspase-3.
Granular Cell Tumor
Immunohistochemical evaluation of cell proliferation antigen Ki-67 and apoptosis-related proteins Bcl-2 and caspase-3 in oral granular cell tumor.
Granular Cell Tumor
Phosphorylated histone H3, Ki-67, p21, fatty acid synthase, and cleaved caspase-3 expression in benign and atypical granular cell tumors.
Granuloma
Activity of the growth hormone-releasing hormone antagonist MIA602 and its underlying mechanisms of action in sarcoidosis-like granuloma.
Granuloma
Apoptosis is a major cause of so-called "caseous necrosis" in mycobacterial granulomas in HIV-infected patients.
Granuloma
Granuloma formation induced by low-dose chronic silica inhalation is associated with an anti-apoptotic response in Lewis rats.
Granuloma
NK cells and gamma interferon coordinate the formation and function of hepatic granulomas in mice infected with the Francisella tularensis live vaccine strain.
Granuloma
Paeoniflorin targets apoptosis and ameliorates fibrosis in murine schistosomiasis mansoni: A novel insight.
Granuloma
Parasitic helminths induce fetal-like reversion in the intestinal stem cell niche.
Hand, Foot and Mouth Disease
Caspase-3 Inhibition Attenuates the Cytopathic Effects of EV71 Infection.
Head and Neck Neoplasms
A functional variant at the miR-885-5p binding site of CASP3 confers risk of both index and second primary malignancies in patients with head and neck cancer.
Head and Neck Neoplasms
Anticancer activity and differentially expressed genes in head and neck cancer cells treated with a novel cyclin-dependent kinase inhibitor.
Head and Neck Neoplasms
Knockdown of ?-catenin controls both apoptotic and autophagic cell death through LKB1/AMPK signaling in head and neck squamous cell carcinoma cell lines.
Head and Neck Neoplasms
Low-intensity ultrasound enhances the anticancer activity of cetuximab in human head and neck cancer cells.
Head and Neck Neoplasms
Potential role of caspase-3 and -9 in arsenic trioxide-mediated apoptosis in PCI-1 head and neck cancer cells.
Head and Neck Neoplasms
Synergistic cytotoxicity of oncolytic reovirus in combination with cisplatin-paclitaxel doublet chemotherapy.
Hearing Loss
Caspase inhibitors, but not c-Jun NH2-terminal kinase inhibitor treatment, prevent cisplatin-induced hearing loss.
Hearing Loss
Caspase-3-deficiency induces hyperplasia of supporting cells and degeneration of sensory cells resulting in the hearing loss.
Hearing Loss, Noise-Induced
Associations of genetic variation in CASP3 gene with noise-induced hearing loss in a Chinese population: a case-control study.
Hearing Loss, Sensorineural
Melody, an ENU mutation in Caspase 3, alters the catalytic cysteine residue and causes sensorineural hearing loss in mice.
Heart Arrest
Activation of CPP-32 protease in hippocampal neurons following ischemia and epilepsy.
Heart Arrest
Early processing of Bid and caspase-6, -8, -10, -14 in the canine brain during cardiac arrest and resuscitation.
Heart Arrest
Niacin and Selenium Attenuate Brain Injury After Cardiac Arrest in Rats by Up-Regulating DJ-1-Akt Signaling.
Heart Arrest
Peroxynitrite and caspase-3 expression after ischemia/reperfusion in mouse cardiac arrest model.
Heart Arrest
Prolonged therapeutic hypothermia is more effective in attenuating brain apoptosis in a Swine cardiac arrest model.
Heart Arrest
Protein kinase C delta cleavage initiates an aberrant signal transduction pathway after cardiac arrest and oxygen glucose deprivation.
Heart Arrest
Pyruvate enhances neurological recovery following cardiopulmonary arrest and resuscitation.
Heart Arrest
Spatial resolution of phospholipid scramblase 1 (PLSCR1), caspase-3 activation and DNA-fragmentation in the human hippocampus after cerebral ischemia.
Heart Arrest
Stabilization of HIF-1? modulates VEGF and caspase-3 in hippocampus of rats following transient global ischemia induced by asphyxial cardiac arrest.
Heart Arrest
The effect of intracerebroventricular application of the caspase-3 inhibitor zDEVD-FMK on neurological outcome and neuronal cell death after global cerebral ischaemia due to cardiac arrest in rats.
Heart Arrest
Therapeutic Hypothermia Enhances Cold-Inducible RNA-Binding Protein Expression and Inhibits Mitochondrial Apoptosis in a Rat Model of Cardiac Arrest.
Heart Arrest
[Effects of brain necroptosis and cytokines expression array on brain injury in rats with cardiac arrest].
Heart Failure
Activation of Rho-associated coiled-coil protein kinase 1 (ROCK-1) by caspase-3 cleavage plays an essential role in cardiac myocyte apoptosis.
Heart Failure
Additional use of immunostaining for active caspase 3 and cleaved actin and PARP fragments to detect apoptosis in patients with chronic heart failure.
Heart Failure
Apoptosis in heart failure: release of cytochrome c from mitochondria and activation of caspase-3 in human cardiomyopathy.
Heart Failure
Berberine inhibits cardiac remodeling of heart failure after myocardial infarction by reducing myocardial cell apoptosis in rats.
Heart Failure
Brain derived neurotrophic factor contributes to the cardiogenic potential of adult resident progenitor cells in failing murine heart.
Heart Failure
Early Administration of Carvedilol Protected against Doxorubicin-Induced Cardiomyopathy.
Heart Failure
Effects of Active Components of Fuzi and Gancao Compatibility on Bax, Bcl-2, and Caspase-3 in Chronic Heart Failure Rats.
Heart Failure
Exendin-4 therapy still offered an additional benefit on reducing transverse aortic constriction-induced cardiac hypertrophy-caused myocardial damage in DPP-4 deficient rats.
Heart Failure
Global secretome analysis of resident cardiac progenitor cells from wild-type and transgenic heart failure mice: Why ambience matters.
Heart Failure
Histopathological Changes in the Kidney following Congestive Heart Failure by Volume Overload in Rats.
Heart Failure
Inhibitory cardiac transcription factor, SRF-N, is generated by caspase 3 cleavage in human heart failure and attenuated by ventricular unloading.
Heart Failure
Intermedin attenuates myocardial infarction through activation of autophagy in a rat model of ischemic heart failure via both cAMP and MAPK/ERK1/2 pathways.
Heart Failure
Investigation of apoptosis in a canine model of chronic heart failure induced by tachycardia.
Heart Failure
Involvement of Endoplasmic Reticulum Stress-Mediated Activation of C/EBP Homologous Protein in Aortic Regurgitation-Induced Cardiac Remodeling in Mice.
Heart Failure
Involvement of mitogen-activated protein kinases in adriamycin-induced cardiomyopathy.
Heart Failure
Latent-transforming growth factor ?-binding protein 2 accelerates cardiac fibroblast apoptosis by regulating the expression and activity of caspase-3.
Heart Failure
Liguzinediol improved the heart function and inhibited myocardial cell apoptosis in rats with heart failure.
Heart Failure
Matrine attenuates focal cerebral ischemic injury by improving antioxidant activity and inhibiting apoptosis in mice.
Heart Failure
Nutritional leucine supplementation attenuates cardiac failure in tumour-bearing cachectic animals.
Heart Failure
Pathological alterations in liver injury following congestive heart failure induced by volume overload in rats.
Heart Failure
Serum levels of melatonin may contribute to the pathogenesis of heart failure in children with median age of 1 year.
Heart Failure
Shikonin ameliorates isoproterenol (ISO)-induced myocardial damage through suppressing fibrosis, inflammation, apoptosis and ER stress.
Heart Failure
The immunohistochemical evaluation of selected markers in the left atrium of dogs with end-stage dilated cardiomyopathy and myxomatous mitral valve disease - a preliminary study.
Heart Failure
[Effect of Moxibustion Stimulation of "Feishu" (BL 13) and "Xinshu" (BL 15) on Expression of Myocardial MyD 88 Protein and Caspase 3 mRNA in Chronic Heart Failure Rats].
Heart Neoplasms
Antioxidant and antiapoptotic effects of proanthocyanidin and ginkgo biloba extract against doxorubicin-induced cardiac injury in rats.
Heart Septal Defects, Ventricular
Type 2 diabetes mellitus induces congenital heart defects in murine embryos by increasing oxidative stress, endoplasmic reticulum stress and apoptosis.
HELLP Syndrome
Placental apoptosis in preeclampsia, intrauterine growth retardation, and HELLP syndrome: an immunohistochemical study with caspase-3 and bcl-2.
Hemangioma
Expression and significance of Bcl-2, Bax, Fas and caspase-3 in different phases of human hemangioma.
Hemangioma
Long non-coding RNA NEAT1 promotes the progression of hemangioma via the miR-361-5p/VEGFA pathway.
Hemangioma
Molecular and immunohistochemical expression of apoptotic proteins Bax, Bcl-2 and Caspase 3 in infantile hemangioma tissues as an effect of propranolol treatment.
Hematologic Neoplasms
Apoptotic mechanism of human leukemia K562/A02 cells induced by magnetic iron oxide nanoparticles co-loaded with daunorubicin and 5-bromotetrandrin.
Hematologic Neoplasms
In vitro cytotoxicity of the novel antimyeloma agents perifosine, bortezomib and lenalidomide against different cell lines.
Hemorrhagic Fever with Renal Syndrome
[The pathogenetic role of peripheral T-lymphocytes activation-induced cell death in hemorrhagic fever with renal syndrome]
Hemorrhagic Fever, Crimean
Evaluation of serum perforin, caspase-3, sFasL and M-30 levels as apoptotic markers in children with Crimean-Congo hemorrhagic fever.
Hemorrhagic Stroke
Effect of active fraction of cerebral on expression of caspase-3 and beta-amyloid precursor protein during therapy of hemorrhagic stroke in the acute and delayed periods.
Hepatic Encephalopathy
Ameliorative effect of Magnesium Isoglycyrrhizinate on hepatic encephalopathy by Epirubicin.
Hepatitis
Activation of caspases in lethal experimental hepatitis and prevention by acute phase proteins.
Hepatitis
Apoptosis in chronic viral hepatitis parallels histological activity: an immunohistochemical investigation using anti-activated caspase-3 and M30 cytodeath antibody.
Hepatitis
Apoptosis in postweaning multisystemic wasting syndrome (PMWS) hepatitis in pigs naturally infected with porcine circovirus type 2 (PCV2).
Hepatitis
COMMD1-Deficient Dogs Accumulate Copper in Hepatocytes and Provide a Good Model for Chronic Hepatitis and Fibrosis.
Hepatitis
Effects of dietary corn bran hemicellulose and neomycin on hepatic caspase-3 activity and glycoprotein concentration in rats treated with or without D-galactosamine.
Hepatitis
Expression of TLR-2 in hepatocellular carcinoma is associated with tumour proliferation, angiogenesis and Caspase-3 expression.
Hepatitis
Features of cell death in brain and liver, the target tissues of progressive neuronal degeneration of childhood with liver disease (Alpers-Huttenlocher disease).
Hepatitis
Foxp3 expression in liver correlates with the degree but not the cause of inflammation.
Hepatitis
Inhibitory effect of M50054, a novel inhibitor of apoptosis, on anti-Fas-antibody-induced hepatitis and chemotherapy-induced alopecia.
Hepatitis
NFkappaB mediates apoptosis through transcriptional activation of Fas (CD95) in adenoviral hepatitis.
Hepatitis
[Preparation and identification of hammerhead ribozyme in vitro against rat caspase-3 mRNA fragment]
Hepatitis B
A network pharmacology study on the Tripteryguim wilfordii Hook for treatment of Crohn's disease.
Hepatitis B
IFN-gamma induces cell death in human hepatoma cells through a TRAIL/death receptor-mediated apoptotic pathway.
Hepatitis B
Potential Molecular Mechanisms of Plantain in the Treatment of Gout and Hyperuricemia Based on Network Pharmacology.
Hepatitis B
The hepatitis B virus-X protein activates a phosphatidylinositol 3-kinase-dependent survival signaling cascade.
Hepatitis B
[Expression of Caspase-3 increased in children with hepatitis B virus-associated membranous nephropathy]
Hepatitis C
A bioinformatics investigation into the pharmacological mechanisms of the effect of the Yinchenhao decoction on hepatitis C based on network pharmacology.
Hepatitis C
Autophagy, apoptosis, vitamin D, and vitamin D receptor in hepatocellular carcinoma associated with hepatitis C virus.
Hepatitis C
Cleavage of the hepatitis C virus NS5A protein by caspase-3 in the interferon sensitivity-determining region in a sequence-dependent manner.
Hepatitis C
Decreased expression of CD28 coincides with the down-modulation of CD3zeta and augmentation of caspase-3 activity in T cells from hepatocellular carcinoma-bearing patients and hepatitis C virus-infected patients.
Hepatitis C
In the peripheral blood mononuclear cells (PBMCs) of HCV infected patients the expression of STAT1 and IRF-1 is downregulated while that of caspase-3 upregulated.
Hepatitis C
Steatosis and liver cell apoptosis in chronic hepatitis C: a mechanism for increased liver injury.
Hepatitis C
Treatment of hepatitis C virus core-positive hepatocytes with the transfer of recombinant caspase-3 using the 2',5'-oligoadenylate synthetase gene promoter.
Hepatitis C, Chronic
Expression of tumour necrosis factor-related apoptosis-inducing ligand and caspase-3 in relation to grade of inflammation and stage of fibrosis in chronic hepatitis C.
Hepatitis, Alcoholic
The effect of melaxen on the activity of caspases and the glutathione antioxidant system in toxic liver injury.
Hepatitis, Chronic
[Expression of CPP32, Fas and Fas ligand and the relationship between their expression and viral antigens in chronic hepatitis]
Hepatoblastoma
Apoptosis induced in hepatoblastoma HepG2 cells by the proteasome inhibitor MG132 is associated with hydrogen peroxide production, expression of Bcl-XS and activation of caspase-3.
Hepatoblastoma
Goniothalamin selectively induces apoptosis on human hepatoblastoma cells through caspase-3 activation.
Hepatoblastoma
The effects of garlic-derived sulfur compounds on cell proliferation, caspase 3 activity, thiol levels and anaerobic sulfur metabolism in human hepatoblastoma HepG2 cells.
Hepatomegaly
Protective effect of Trillium tschonoskii saponin on CCl4-induced acute liver injury of rats through apoptosis inhibition.
Hepatopulmonary Syndrome
Caspase-3 inhibition prevents the development of hepatopulmonary syndrome in common bile duct ligation rats by alleviating pulmonary injury.
Herpes Simplex
A novel method for imaging apoptosis using a caspase-1 near-infrared fluorescent probe.
Herpes Simplex
Activation of caspase-3 noninvolved in the bystander effect of the herpes simplex virus thymidine kinase gene/ganciclovir (HSV-tk/GCV) system.
Herpes Simplex
Herpes simplex virus 1 inhibits apoptosis through a caspase-3-dependent pathway in primary cultures of cortical neuronal cells of fetal mice.
Herpes Simplex
Herpes simplex virus thymidine kinase/ganciclovir-induced cell death is enhanced by co-expression of caspase-3 in ovarian carcinoma cells.
Herpes Simplex
Herpes simplex virus type 1-induced encephalitis has an apoptotic component associated with activation of c-Jun N-terminal kinase.
Herpes Simplex
ICP10PK inhibits calpain-dependent release of apoptosis-inducing factor and programmed cell death in response to the toxin MPP+.
Herpes Simplex
Induction of apoptosis by herpes simplex virus in Jurkat cells is partly through caspase-3, -8 and -9 activation.
Herpes Simplex
Molecular Targets and Mechanisms of Scutellariae radix-Coptidis rhizoma Drug Pair for the Treatment of Ulcerative Colitis Based on Network Pharmacology and Molecular Docking.
Herpes Simplex
Stable cell lines expressing high levels of the herpes simplex virus type 1 LAT are refractory to caspase 3 activation and DNA laddering following cold shock induced apoptosis.
Herpes Simplex
Tau cleavage at D421 by caspase-3 is induced in neurons and astrocytes infected with herpes simplex virus type 1.
Herpes Simplex
The herpes simplex virus type 1 (HSV-1) latency-associated transcript (LAT) protects cells against cold-shock-induced apoptosis by maintaining phosphorylation of protein kinase B (AKT).
Herpes Simplex
The herpes simplex virus type 2 gene ICP10PK protects from apoptosis caused by nerve growth factor deprivation through inhibition of caspase-3 activation and XIAP up-regulation.
Herpes Simplex
U(S)3 protein kinase of herpes simplex virus 1 blocks caspase 3 activation induced by the products of U(S)1.5 and U(L)13 genes and modulates expression of transduced U(S)1.5 open reading frame in a cell type-specific manner.
Herpes Zoster
Ambient levels of concentrated PM2.5 affects cell kinetics in adrenal glands: an experimental study in mice.
Herpes Zoster
Caspase-1 Inhibitor Prevents Neurogenic Pulmonary Edema After Subarachnoid Hemorrhage in Mice.
Herpes Zoster
Caspase-3 and Bcl-2 expression in aging in adrenal zona reticularis after dexamethasone administration.
Herpes Zoster
Decrease in Lipid Droplets in Adrenal Cortex of Male Wistar Rats after Chronic Exposure to Energy Drinks.
Herpes Zoster
Histological effect of nicotine on adrenal zona fasciculata and the effect of grape seed extract with or without withdrawal of nicotine.
Histiocytic Sarcoma
Fas-ligand and caspase-3 positivity in three cases of histiocytic sarcoma: a different etiopathogenic pathway?
Histiocytic Sarcoma
[Role of proteins in Fas-mediated apoptosis in tumor cells and lymphocytes co-cultured in vitro]
HIV Infections
Increased sensitivity of T lymphocytes to tumor necrosis factor receptor 1 (TNFR1)- and TNFR2-mediated apoptosis in HIV infection: relation to expression of Bcl-2 and active caspase-8 and caspase-3.
HIV-Associated Lipodystrophy Syndrome
Immunohistochemical analysis of the expression of TNF-alpha, TGF-beta, and caspase-3 in subcutaneous tissue of patients with HIV Lipodystrophy Syndrome.
Hodgkin Disease
Characterization of the interleukin-1beta-converting enzyme/ced-3-family protease, caspase-3/CPP32, in Hodgkin's disease: lack of caspase-3 expression in nodular lymphocyte predominance Hodgkin's disease.
Hodgkin Disease
cIAP2 is highly expressed in Hodgkin-Reed-Sternberg cells and inhibits apoptosis by interfering with constitutively active caspase-3.
Hodgkin Disease
Expression of the active caspase-3 in children and adolescents with classical Hodgkin lymphoma.
Hodgkin Disease
Frequent nuclear localization of ICAD and cytoplasmic co-expression of caspase-8 and caspase-3 in human lymphomas.
Hodgkin Disease
Pathway-focused gene expression profiles and immunohistochemistry detection identify contrasting association of caspase 3 (CASP3) expression with prognosis in pediatric classical Hodgkin lymphoma.
Hodgkin Disease
Transfection of caspase-3 in the caspase-3-deficient Hodgkin's disease cell line, KMH2, results in enhanced sensitivity to CD95-, TRAIL-, and ARA-C-induced apoptosis.
Huntington Disease
Huntingtin fragmentation and increased caspase 3, 8 and 9 activities in lymphoblasts with heterozygous and homozygous Huntington's disease mutation.
Huntington Disease
Implication of Caspase-3 as a Common Therapeutic Target for Multineurodegenerative Disorders and Its Inhibition Using Nonpeptidyl Natural Compounds.
Huntington Disease
Increased caspase-2, calpain activations and decreased mitochondrial complex II activity in cells expressing exogenous huntingtin exon 1 containing CAG repeat in the pathogenic range.
Huntington Disease
Minocycline inhibits caspase-1 and caspase-3 expression and delays mortality in a transgenic mouse model of Huntington disease.
Huntington Disease
Neuroprotective and neurotrophic actions of the mood stabilizer lithium: can it be used to treat neurodegenerative diseases?
Huntington Disease
Neuroprotective effects of M826, a reversible caspase-3 inhibitor, in the rat malonate model of Huntington's disease.
Hydatidiform Mole
Diagnostic and Pathogenetic Significance of Increased Stromal Apoptosis and Incomplete Vasculogenesis in Complete Hydatidiform Moles in Very Early Pregnancy Periods.
Hydrocephalus
Detection of caspase-3, neuron specific enolase, and high-sensitivity C-reactive protein levels in both cerebrospinal fluid and serum of patients after aneurysmal subarachnoid hemorrhage.
Hydrocephalus
Soluble Fas (CD95/Apo-1), soluble Fas ligand, and activated caspase 3 in the cerebrospinal fluid of infants with posthemorrhagic and nonhemorrhagic hydrocephalus.
Hydrocephalus, Normal Pressure
Detection of caspase-3, neuron specific enolase, and high-sensitivity C-reactive protein levels in both cerebrospinal fluid and serum of patients after aneurysmal subarachnoid hemorrhage.
Hydronephrosis
Acute kidney injury induced by pneumoperitoneum pressure via a mitochondrial injury-dependent mechanism in a rabbit model of different degrees of hydronephrosis.
Hydronephrosis
GSDME-mediated pyroptosis promotes inflammation and fibrosis in obstructive nephropathy.
Hydronephrosis
Repression of apurinic/apyrimidinic endonuclease by p53-dependent apoptosis in hydronephrosis-induced rat kidney.
Hyperalgesia
A single subcutaneous injection of ozone prevents allodynia and decreases the over-expression of pro-inflammatory caspases in the orbito-frontal cortex of neuropathic mice.
Hyperalgesia
Biomarker Analysis of Orally Dosed, Dual Active, Matrix Metalloproteinase (MMP)-2 and MMP-9 Inhibitor, AQU-118, in the Spinal Nerve Ligation (SNL) Rat Model of Neuropathic Pain.
Hyperalgesia
BNSTAV GABA-PVNCRF Circuit Regulates Visceral Hypersensitivity Induced by Maternal Separation in Vgat-Cre Mice.
Hyperalgesia
Melatonin MT2 receptor agonist IIK-7 produces antinociception by modulation of ROS and suppression of spinal microglial activation in neuropathic pain rats.
Hyperalgesia
Microglial-induced apoptosis is potentially responsible for hyperalgesia variations during CFA-induced inflammation.
Hyperalgesia
Neuroprotective and antinociceptive effects of rosemary (Rosmarinus officinalis L.) extract in rats with painful diabetic neuropathy.
Hyperalgesia
Neuroprotective effect of l-theanine in a rat model of chronic constriction injury of sciatic nerve-induced neuropathic pain.
Hyperalgesia
Normalizing JMJD6 Expression in Rat Spinal Dorsal Horn Alleviates Hyperalgesia Following Chronic Constriction Injury.
Hyperalgesia
Peripheral noxious stimulation reduces withdrawal threshold to mechanical stimuli after spinal cord injury: role of tumor necrosis factor alpha and apoptosis.
Hyperalgesia
Satureja khuzestanica attenuates apoptosis in hyperglycemic PC12 cells and spinal cord of diabetic rats.
Hyperalgesia
Sesamol Suppresses Neuro-Inflammatory Cascade in Experimental Model of Diabetic Neuropathy.
Hyperalgesia
Spinal caspase-3 contributes to tibial fracture-associated postoperative allodynia via up-regulation of LRRTM1 expression in mice.
Hyperalgesia
Tocotrienol attenuates oxidative-nitrosative stress and inflammatory cascade in experimental model of diabetic neuropathy.
Hypercholesterolemia
Effects and mechanism of turmeric vasorelaxation of the thoracic aorta in hypercholesterolemic rats.
Hypercholesterolemia
Increased cardiomyocyte apoptosis following ischemia and reperfusion in diet-induced hypercholesterolemia: relation to Bcl-2 and Bax proteins and caspase-3 activity.
Hyperemia
Gastric mucosal inflammatory responses toHelicobacter pylori lipopolysaccharide: Suppression of caspase-3 and nitric oxide synthase-2 by omeprazole and sucralfate.
Hyperemia
Venous congestion induces mucosal apoptosis via tumor necrosis factor-alpha-mediated cell death in the rat small intestine.
Hyperglycemia
Allicin modulates diclofenac sodium induced hepatonephro toxicity in rats via reducing oxidative stress and caspase 3 protein expression.
Hyperglycemia
Aqueous anise extract alleviated the pancreatic changes in streptozotocin-induced diabetic rat model via modulation of hyperglycemia, oxidative stress, apoptosis and autophagy: A biochemical, histological and immunohistochemical study.
Hyperglycemia
Bamboo leaf extract ameliorates diabetic nephropathy through activating the AKT signaling pathway in rats.
Hyperglycemia
Beneficial effects of fenofibrate in retinal pigment epithelium by the modulation of stress and survival signaling under diabetic conditions.
Hyperglycemia
Colonic motor dysfunction in human diabetes is associated with enteric neuronal loss and increased oxidative stress.
Hyperglycemia
Combined effects of hyperglycemic conditions and HIV-1 Nef: a potential model for induced HIV neuropathogenesis.
Hyperglycemia
Critical role of TXNIP in oxidative stress, DNA damage and retinal pericyte apoptosis under high glucose: Implications for diabetic retinopathy.
Hyperglycemia
Diabetes triggers a PARP1 mediated death pathway in the heart through participation of FoxO1.
Hyperglycemia
Diazoxide preconditioning of endothelial progenitor cells from streptozotocin-induced type 1 diabetic rats improves their ability to repair diabetic cardiomyopathy.
Hyperglycemia
Evaluation of Bcl-2 family gene expression and Caspase-3 activity in hippocampus STZ-induced diabetic rats.
Hyperglycemia
Ganglion cells apoptosis in diabetic rats as early prediction of glaucoma: a study of Brn3b gene expression and association with change of quantity of NO, caspase-3, NF-?B, and TNF-?.
Hyperglycemia
Ginger alleviates hyperglycemia-induced oxidative stress, inflammation and apoptosis and protects rats against diabetic nephropathy.
Hyperglycemia
High glucose concentrations alter hypoxia-induced control of vascular smooth muscle cell growth via a HIF-1alpha-dependent pathway.
Hyperglycemia
Hyperglycemia abolished Drp-1-mediated mitophagy at the early stage of cerebral ischemia.
Hyperglycemia
Hyperglycemia induces apoptosis in rat liver through the increase of hydroxyl radical: new insights into the insulin effect.
Hyperglycemia
Hyperspectral imaging for simultaneous measurements of two FRET biosensors in pancreatic ?-cells.
Hyperglycemia
Impact of hyperglycemia on neuronal apoptosis after subarachnoid hemorrhage in rodent brain: An experimental research.
Hyperglycemia
Mangiferin Enhanced Autophagy via Inhibiting mTORC1 Pathway to Prevent High Glucose-Induced Cardiomyocyte Injury.
Hyperglycemia
Mitochondrial biogenesis and fission in axons in cell culture and animal models of diabetic neuropathy.
Hyperglycemia
Neuroprotective and antinociceptive effects of rosemary (Rosmarinus officinalis L.) extract in rats with painful diabetic neuropathy.
Hyperglycemia
Prophylactic role of arjunolic acid in response to streptozotocin mediated diabetic renal injury: activation of polyol pathway and oxidative stress responsive signaling cascades.
Hyperglycemia
Protective effects of taurine on endothelial cells impaired by high glucose and oxidized low density lipoproteins.
Hyperglycemia
Protective role of D-saccharic acid-1,4-lactone in alloxan induced oxidative stress in the spleen tissue of diabetic rats is mediated by suppressing mitochondria dependent apoptotic pathway.
Hyperglycemia
Resveratrol alleviates diabetes-induced testicular dysfunction by inhibiting oxidative stress and c-Jun N-terminal kinase signaling in rats.
Hyperglycemia
Satureja khuzestanica attenuates apoptosis in hyperglycemic PC12 cells and spinal cord of diabetic rats.
Hyperglycemia
SOD2 protects neurons from injury in cell culture and animal models of diabetic neuropathy.
Hyperglycemia
Streptozotocin induced activation of oxidative stress responsive splenic cell signaling pathways: protective role of arjunolic acid.
Hyperglycemia
The Effects of Diabetes Mellitus on Ovarian Injury and Reserve: An Experimental Study.
Hyperglycemia
The effects of safranal, a constitute of saffron, and metformin on spatial learning and memory impairments in type-1 diabetic rats: behavioral and hippocampal histopathological and biochemical evaluations.
Hyperglycemia
[Effect of GABA(B) Receptor Signal to Corticosterone-induced Neuron Apoptosis].
Hyperhomocysteinemia
Hyperhomocysteinemia alters cytokine gene expression, cytochrome c oxidase activity and oxidative stress in striatum and cerebellum of rodents.
Hyperhomocysteinemia
Melatonin inhibits neural apoptosis induced by homocysteine in hippocampus of rats via inhibition of cytochrome c translocation and caspase-3 activation and by regulating pro- and anti-apoptotic protein levels.
Hyperlipidemias
Effect of folic acid and vitamin B12 on the expression of PPAR?, caspase-3 and caspase-8 mRNA in the abdominal aortas of rats with hyperlipidemia.
Hyperlipidemias
Hyperlipidemia exacerbates cerebral injury through oxidative stress, inflammation and neuronal apoptosis in MCAO/reperfusion rats.
Hyperlipidemias
Impact of bone-marrow-derived mesenchymal stem cells on adriamycin-induced chronic nephropathy.
Hyperlipidemias
[Effect of Electroacupuncture on Cerebro-cortex Caspase-3 Expression and Blood Lipid Levels in Hyperlipemia Rats with Cerebral Ischemia].
Hypersensitivity
"Anti-Inflammatory Effects of Probiotic Lactobacillus paracasi on Ventricles of BALB/C Mice Treated with Ovalbumin".
Hypersensitivity
Advanced Oxidative Protein Products Cause Pain Hypersensitivity in Rats by Inducing Dorsal Root Ganglion Neurons Apoptosis via NADPH Oxidase 4/c-Jun N-terminal Kinase Pathways.
Hypersensitivity
Changes in lamina structure are followed by spatial reorganization of heterochromatic regions in caspase-8-activated human mesenchymal stem cells.
Hypersensitivity
Clonidine reduces hypersensitivity and alters the balance of pro- and anti-inflammatory leukocytes after local injection at the site of inflammatory neuritis.
Hypersensitivity
Effects of combined exposure to formaldehyde and benzene on immune cells in the blood and spleen in Balb/c mice.
Hypersensitivity
Low-dose radiation hypersensitivity is associated with p53-dependent apoptosis.
Hypersensitivity
Restoration of Cingulate Long-Term Depression by Enhancing Non-apoptotic Caspase 3 Alleviates Peripheral Pain Hypersensitivity.
Hypersensitivity
SHP-2 regulates the phosphatidylinositide 3'-kinase/Akt pathway and suppresses caspase 3-mediated apoptosis.
Hypersensitivity
Spinal caspase-3 contributes to tibial fracture-associated postoperative allodynia via up-regulation of LRRTM1 expression in mice.
Hypersensitivity
Ubiquitination and degradation of the FADD adaptor protein regulate death receptor-mediated apoptosis and necroptosis.
Hypertension
Angiotensin II type 1 receptor-activated caspase-3 through ras/mitogen-activated protein kinase/extracellular signal-regulated kinase in the rostral ventrolateral medulla is involved in sympathoexcitation in stroke-prone spontaneously hypertensive rats.
Hypertension
Calpain is activated in experimental uremia: is calpain a mediator of uremia-induced myocardial injury?
Hypertension
Correlation of cardiomyocyte apoptosis with duration of hypertension, severity of hypertension and caspase-3 expression in hypertensive rats.
Hypertension
Energy deficit as a possible factor for the induction of caspase-dependent apoptosis in left ventricular myocardial cells during genetically determined and secondary arterial hypertension.
Hypertension
Erythrocyte caspase-3 activation and oxidative imbalance in erythrocytes and in plasma of type 2 diabetic patients.
Hypertension
Erythrocyte caspase-3 and antioxidant defense is activated in red blood cells and plasma of type 2 diabetes patients at first clinical onset.
Hypertension
Herbal compound Naoshuantong capsule attenuates retinal injury in ischemia/reperfusion rat model by inhibiting apoptosis.
Hypertension
Influence of gender on oxidative stress, lipid peroxidation, protein damage and apoptosis in hearts and brains from spontaneously hypertensive rats.
Hypertension
Protective effects of hydrogen sulfide on chronic kidney disease by reducing oxidative stress, inflammation and apoptosis.
Hypertension
Renal sympathetic denervation attenuates hypertension and vascular remodeling in renovascular hypertensive rats.
Hypertension
Reversion of left ventricle remodeling in spontaneously hypertensive rats by valsartan is associated with the inhibition of caspase-3, -8 and -9 activities.
Hypertension
Selected nutraceutic screening by therapeutic effects on doxorubicin-induced chronic kidney disease.
Hypertension
Vaccarin alleviates hypertension and nephropathy in renovascular hypertensive rats.
Hypertension, Portal
Small Liver Remnants Are More Vulnerable to Ischemia/Reperfusion Injury after Extended Hepatectomies: A Case-Control Study.
Hypertension, Pulmonary
Changes in Caspase-3, B Cell Leukemia/Lymphoma-2, Interleukin-6, Tumor Necrosis Factor-? and Vascular Endothelial Growth Factor Gene Expression after Human Umbilical Cord Blood Derived Mesenchymal Stem Cells Transfusion in Pulmonary Hypertension Rat Models.
Hypertension, Pulmonary
Changes of pulmonary pathology and gene expressions after simvastatin treatment in the monocrotaline-induced pulmonary hypertension rat model.
Hypertension, Pulmonary
Inhibition of the VEGF receptor 2 combined with chronic hypoxia causes cell death-dependent pulmonary endothelial cell proliferation and severe pulmonary hypertension.
Hyperthyroidism
Histomorphometry and expression of CDC-47 and caspase-3 in mammary glands of pregnant female rats with artificial hyperthyroidism.
Hyperthyroidism
Histomorphometry and expression of Cdc47 and caspase-3 in hyperthyroid rat uteri and placentas during gestation and postpartum associated with fetal development.
Hyperthyroidism
Hyperthyroidism induces apoptosis in rat liver through activation of death receptor-mediated pathways.
Hyperthyroidism
Severe hyperthyroidism induces mitochondria-mediated apoptosis in rat liver.
Hyperthyroidism
Thyroid status modulates T lymphoma growth via cell cycle regulatory proteins and angiogenesis.
Hypertrophy, Left Ventricular
Regulation of caspase 3 and Fas in pressure overload-induced left ventricular dysfunction.
Hypertrophy, Left Ventricular
Reversion of left ventricle remodeling in spontaneously hypertensive rats by valsartan is associated with the inhibition of caspase-3, -8 and -9 activities.
Hypertrophy, Right Ventricular
Angiotensin-converting enzyme 2 activation suppresses pulmonary vascular remodeling by inducing apoptosis through the Hippo signaling pathway in rats with pulmonary arterial hypertension.
Hypertrophy, Right Ventricular
Effects of HIV Protease Inhibitors on Progression of Monocrotaline- and Hypoxia-Induced Pulmonary Hypertension in Rats.
Hypertrophy, Right Ventricular
Simvastatin causes endothelial cell apoptosis and attenuates severe pulmonary hypertension.
Hypoalbuminemia
Impact of bone-marrow-derived mesenchymal stem cells on adriamycin-induced chronic nephropathy.
Hypoglycemia
A histopathological study of premature and mature infants with pontosubicular neuron necrosis: neuronal cell death in perinatal brain damage.
Hypoglycemia
Biological Characterization of Gene Response to Insulin-Induced Hypoglycemia in Mouse Retina.
Hypoglycemia
Cyclosporin A prevents calpain activation despite increased intracellular calcium concentrations, as well as translocation of apoptosis-inducing factor, cytochrome c and caspase-3 activation in neurons exposed to transient hypoglycemia.
Hypoglycemia
Hypoglycemia induced changes in cell death and cell proliferation in the organogenesis stage embryonic mouse heart.
Hypoglycemia
Repeated Glucose Deprivation/Reperfusion Induced PC-12 Cell Death through the Involvement of FOXO Transcription Factor.
Hypoglycemia
Synthesis and protective effects of aralkyl alcoholic 2-acetamido-2-deoxy-?-d-pyranosides on hypoglycemia and serum limitation induced apoptosis in PC12 cell.
Hypokinesia
Gene disruption of caspase-3 prevents MPTP-induced Parkinson's disease in mice.
Hypospadias
MiR-145-modulated SOX9-mediated hypospadias through acting on mitogen-activated protein kinase signaling pathway.
Hypothyroidism
[Apoptosis, proliferation and spleen histomorphometry of adult female rats with thyroid and ovarian hypofunction]
Hypoxia, Brain
ATP and cytochrome c-dependent activation of caspase-9 during hypoxia in the cerebral cortex of newborn piglets.
Hypoxia, Brain
Mechanism of activation of caspase-9 and caspase-3 during hypoxia in the cerebral cortex of newborn piglets: the role of nuclear Ca2+ -influx.
Hypoxia-Ischemia, Brain
Correlation between caspase-3 activation and three different markers of DNA damage in neonatal cerebral hypoxia-ischemia.
Hypoxia-Ischemia, Brain
hUC-MSCs Exert a Neuroprotective Effect via Anti-apoptotic Mechanisms in a Neonatal HIE Rat Model.
Hypoxia-Ischemia, Brain
Impairment of mitochondrial respiration after cerebral hypoxia-ischemia in immature rats: relationship to activation of caspase-3 and neuronal injury.
Hypoxia-Ischemia, Brain
Subacute Zinc Administration and L-NAME Caused an Increase of NO, Zinc, Lipoperoxidation, and Caspase-3 during a Cerebral Hypoxia-Ischemia Process in the Rat.
Hypoxia-Ischemia, Brain
Synergistic activation of caspase-3 by m-calpain after neonatal hypoxia-ischemia: a mechanism of "pathological apoptosis"?
Hypoxia-Ischemia, Brain
[Effect of hypoxia-ischemia on cysteinyl aspartate-specific proteinases activity in cerebral tissue of neonatal rat]
Hypoxia-Ischemia, Brain
[Effects of selective head cooling with mild hypothermia on serum levels of caspase-3 and IL-18 in neonates with hypoxic-ischemic encephalopathy.]
Infarction, Middle Cerebral Artery
Accumulation of calpain and caspase-3 proteolytic fragments of brain-derived alphaII-spectrin in cerebral spinal fluid after middle cerebral artery occlusion in rats.
Infarction, Middle Cerebral Artery
Activation and cleavage of caspase-3 in apoptosis induced by experimental cerebral ischemia.
Infarction, Middle Cerebral Artery
Alteration in bioenergetic regulators, SirT1 and Parp1 expression precedes oxidative stress in rats subjected to transient cerebral focal ischemia: molecular and histopathologic evidences.
Infarction, Middle Cerebral Artery
Attenuation of oxidative DNA damage with a novel antioxidant EPC-K1 in rat brain neuronal cells after transient middle cerebral artery occlusion.
Infarction, Middle Cerebral Artery
Caspase inhibition attenuates accumulation of beta-amyloid by reducing beta-secretase production and activity in rat brains after stroke.
Infarction, Middle Cerebral Artery
CDP-choline reduces pro-caspase and cleaved caspase-3 expression, nuclear DNA fragmentation, and specific PARP-cleaved products of caspase activation following middle cerebral artery occlusion in the rat.
Infarction, Middle Cerebral Artery
Cleaved caspase-3 expression after experimental stroke exhibits different phenotypes and is predominantly non-apoptotic.
Infarction, Middle Cerebral Artery
Decrease in Oxidative Stress Parameters after Post-Ischaemic Recombinant Human Erythropoietin Administration in the Hippocampus of Rats Exposed to Focal Cerebral Ischaemia.
Infarction, Middle Cerebral Artery
Dual role of caspase-11 in mediating activation of caspase-1 and caspase-3 under pathological conditions.
Infarction, Middle Cerebral Artery
Dynamic expression changes of Bcl-2, Caspase-3 and Hsp70 in middle cerebral artery occlusion rats.
Infarction, Middle Cerebral Artery
Effect of Sevoflurane postconditioning on gene expression in brain tissue of the middle cerebral artery occlusion rat model.
Infarction, Middle Cerebral Artery
Ferulic acid inhibits nitric oxide-induced apoptosis by enhancing GABA(B1) receptor expression in transient focal cerebral ischemia in rats.
Infarction, Middle Cerebral Artery
GlyT1 Inhibitor NFPS Exerts Neuroprotection via GlyR Alpha1 Subunit in the Rat Model of Transient Focal Cerebral Ischaemia and Reperfusion.
Infarction, Middle Cerebral Artery
Human umbilical cord blood cells protect oligodendrocytes from brain ischemia through Akt signal transduction.
Infarction, Middle Cerebral Artery
Immunohistochemical and biochemical assessment of caspase-3 activation and DNA fragmentation following transient focal ischemia in the rat.
Infarction, Middle Cerebral Artery
Increased Renal Dysfunction, Apoptosis, and Fibrogenesis Through Sympathetic Hyperactivity After Focal Cerebral Infarction.
Infarction, Middle Cerebral Artery
Inhibition of microRNA-9-5p and microRNA-128-3p can inhibit ischemic stroke-related cell death in vitro and in vivo.
Infarction, Middle Cerebral Artery
Mild hypothermia modulates the expression of nestin and caspase-3 in the sub-granular zone and improves neurological outcomes in rats with ischemic stroke.
Infarction, Middle Cerebral Artery
Neuroprotective Effects of Chronic Fenofibrate Treatment via Modulating the Immunoreactivity of Cleaved Caspase-3 in Stroke Induced by Transient Middle Cerebral Occlusion Rat Model.
Infarction, Middle Cerebral Artery
Pien-Tze-Huang protects cerebral ischemic injury by inhibiting neuronal apoptosis in acute ischemic stroke rats.
Infarction, Middle Cerebral Artery
Pinacidil reduces neuronal apoptosis following cerebral ischemia-reperfusion in rats through both mitochondrial and death-receptor signal pathways.
Infarction, Middle Cerebral Artery
Serum Caspase-3 Levels and Early Mortality of Patients with Malignant Middle Cerebral Artery Infarction.
Infarction, Middle Cerebral Artery
Tacrolimus (FK506) attenuates biphasic cytochrome c release and Bad phosphorylation following transient cerebral ischemia in mice.
Infarction, Middle Cerebral Artery
Tanshinone IIA attenuates the cerebral ischemic injury-induced increase in levels of GFAP and of caspases-3 and -8.
Infarction, Middle Cerebral Artery
Temporal profile of cytochrome c and caspase-3 immunoreactivities and TUNEL staining after permanent middle cerebral artery occlusion in rats.
Infarction, Middle Cerebral Artery
The effects of middle cerebral artery occlusion on central nervous system apoptotic events in normal and diabetic rats.
Infarction, Middle Cerebral Artery
Tumor necrosis factor-like weak inducer of apoptosis and fibroblast growth factor-inducible 14 mediate cerebral ischemia-induced poly(ADP-ribose) polymerase-1 activation and neuronal death.
Infections
2,3,7,8-Tetrachlorodibenzo-p-dioxin modifies expression and nuclear/cytosolic localization of bovine herpesvirus 1 immediate-early protein (bICP0) during infection.
Infections
A novel method for imaging apoptosis using a caspase-1 near-infrared fluorescent probe.
Infections
A piscine birnavirus induces inhibition of protein synthesis in CHSE-214 cells primarily through the induction of eIF2? phosphorylation.
Infections
A ROS-dependent and Caspase-3-mediated apoptosis in sheep bronchial epithelial cells in response to Mycoplasma Ovipneumoniae infections.
Infections
A Simian Virus 5 (SV5) P/V Mutant Is Less Cytopathic than Wild-Type SV5 in Human Dendritic Cells and Is a More Effective Activator of Dendritic Cell Maturation and Function.
Infections
A tumour necrosis factor receptor-like protein encoded by Singapore grouper iridovirus modulates cell proliferation, apoptosis and viral replication.
Infections
A20 Restricts Inflammatory Response and Desensitizes Gingival Keratinocytes to Apoptosis.
Infections
Activation of caspase-3 and cleavage of Rb are associated with p16-mediated apoptosis in human non-small cell lung cancer cells.
Infections
Activation of caspase-3 by the Dot/Icm virulence system is essential for arrested biogenesis of the Legionella-containing phagosome.
Infections
Activation of caspase-3 during Chlamydia trachomatis-induced apoptosis at a late stage.
Infections
Activation of the phosphatidylinositol 3-kinase/Akt signaling pathway during porcine circovirus type 2 infection facilitates cell survival and viral replication.
Infections
ACTIVATION OF THE PI3K/Akt PATHWAY EARLY DURING VACCINIA AND COWPOX VIRUS INFECTION IS REQUIRED FOR BOTH HOST SURVIVAL AND VIRAL REPLICATION.
Infections
Active suppression of the pulmonary immune response by Francisella tularensis Schu4.
Infections
Acute and chronic infection of H. pylori caused the difference in apoptosis of gastric epithelial cells.
Infections
Adenovirus-mediated down-regulation of X-linked inhibitor of apoptosis protein inhibits colon cancer.
Infections
Adenovirus-Mediated Gene Transfer of FKHRL1 Triple Mutant Efficiently Induces Apoptosis in Melanoma Cells.
Infections
Adenovirus-mediated heme oxygenase-1 gene expression stimulates apoptosis in vascular smooth muscle cells.
Infections
Adenovirus-mediated transfer of caspase-3 with Fas ligand induces drastic apoptosis in U-373MG glioma cells.
Infections
Adenovirus-mediated transfer of p53 augments hyperthermia-induced apoptosis in U251 glioma cells.
Infections
African swine fever virus IAP homologue inhibits caspase activation and promotes cell survival in mammalian cells.
Infections
Aggregatibacter actinomycetemcomitans infection enhances apoptosis in vivo through a caspase-3-dependent mechanism in experimental periodontitis.
Infections
Alphaviruses induce apoptosis in Bcl-2-overexpressing cells: evidence for a caspase-mediated, proteolytic inactivation of Bcl-2.
Infections
Alteration of NF-kappaB activity leads to mitochondrial apoptosis after infection with pathological prion protein.
Infections
Altered mast cell activity in response to rhinovirus infection provides novel insight into asthma.
Infections
ALV-J infection induces chicken monocyte death accompanied with the production of IL-1? and IL-18.
Infections
An image cytometric technique is a concise method to detect adenoviruses and host cell proteins and to monitor the infection and cellular responses induced.
Infections
Analysis of the anti-apoptotic activity of four vaccinia virus proteins demonstrates that B13 is the most potent inhibitor in isolation and during viral infection.
Infections
Anaplasma phagocytophilum inhibits human neutrophil apoptosis via upregulation of bfl-1, maintenance of mitochondrial membrane potential and prevention of caspase 3 activation.
Infections
Anti-apoptotic effects of SERPIN B3 and B4 via STAT6 activation in macrophages after infection with Toxoplasma gondii.
Infections
Antigen detection and apoptosis in Mongolian gerbil's kidney experimentally intraperitoneally infected by swine hepatitis E virus.
Infections
Antitumor potential of SLPI promoter controlled recombinant caspase-3 expression in laryngeal carcinoma.
Infections
Antiviral interferons induced by Newcastle disease virus (NDV) drive a tumor-selective apoptosis.
Infections
Apoptosis and S phase of the cell cycle in BeWo trophoblastic and HeLa cells are differentially modulated by Toxoplasma gondii strain types.
Infections
Apoptosis as the adaptation mechanism in survival of Trichinella spiralis in the host.
Infections
Apoptosis in a Whitefly Vector Activated by a Begomovirus Enhances Viral Transmission.
Infections
Apoptosis in different gastric lesions and gastric cancer: relationship with Helicobacter pylori, overexpression of p53 and aneuploidy.
Infections
Apoptosis in Normal and Coxiella burnetii-Infected Placentas From Alaskan Northern Fur Seals (Callorhinus ursinus).
Infections
Apoptosis in porcine macrophages infected in vitro with African swine fever virus (ASFV) strains with different virulence.
Infections
Apoptosis induced in an early step of African swine fever virus entry into vero cells does not require virus replication.
Infections
Apoptosis of hippocampal pyramidal neurons is virus independent in a mouse model of acute neurovirulent picornavirus infection.
Infections
Apoptosis of human gastric epithelial cells via caspase-3 activation in response to Helicobacter pylori infection: possible involvement of neutrophils through tumor necrosis factor alpha and soluble Fas ligands.
Infections
Apoptosis of human retina and retinal pigment cells induced by human cytomegalovirus infection.
Infections
Apoptosis phenomenon in the schistosomulum and adult worm life cycle stages of Schistosoma japonicum.
Infections
Apoptosis-inducing factor participation in bovine macrophage Mycobacterium bovis-induced caspase-independent cell death.
Infections
Apoptotic and necrotic changes in cultured murine neurons infected with equid herpesvirus 1.
Infections
Apoptotic cell death induced by Acinetobacter baumannii in epithelial cells through caspase-3 activation.
Infections
Apoptotic deletion of Th cells specific for the 19-kDa carboxyl-terminal fragment of merozoite surface protein 1 during malaria infection.
Infections
Apoptotic effects of antimalarial artemisinin on the second generation merozoites of Eimeria tenella and parasitized host cells.
Infections
Artemisinin and Artemisia annua leaves alleviate Eimeria tenella infection by facilitating apoptosis of host cells and suppressing inflammatory response.
Infections
Asc-dependent and independent mechanisms contribute to restriction of legionella pneumophila infection in murine macrophages.
Infections
Atrophy and Death of Nonpeptidergic and Peptidergic Nociceptive Neurons in SIV Infection.
Infections
Autophagy Delays Apoptotic Cell Death Induced by Siniperca chuatsi Rhabdovirus in Epithelioma Papulosum Cyprinid Cells.
Infections
Autophagy protects against retinal cell death in mouse model of cytomegalovirus retinitis.
Infections
Bacterial induction of early response genes and activation of proapoptotic factors in pleural mesothelial cells.
Infections
BAG3 protein regulates caspase-3 activation in HIV-1-infected human primary microglial cells.
Infections
Bax inhibitor-1 from orange spotted grouper, Epinephelus coioides involved in viral infection.
Infections
Bax is activated during rotavirus-induced apoptosis through the mitochondrial pathway.
Infections
Bidirectional increase in permeability of nuclear envelope upon poliovirus infection and accompanying alterations of nuclear pores.
Infections
Bik Mediates Caspase-dependent Cleavage of Viral Proteins to Promote Influenza A Virus Infection.
Infections
Biochemical Variations in Cytolytic Activity of Ortho- and Paramyxoviruses in Human Lung Tumor Cell Culture.
Infections
Both PI3K- and mTOR-signaling pathways take part in CVB3-induced apoptosis of Hela cells.
Infections
C-X-C motif chemokine ligand 10 produced by mouse Sertoli cells in response to mumps virus infection induces male germ cell apoptosis.
Infections
Calcineurin-mediated hypertrophy protects cardiomyocytes from apoptosis in vitro and in vivo: An apoptosis-independent model of dilated heart failure.
Infections
cAMP Receptor Protein of Salmonella enterica Serovar Typhimurium Modulate Glycolysis in Macrophages to Induce Cell Apoptosis.
Infections
Canine distemper virus induces apoptosis through caspase-3 and -8 activation in vero cells.
Infections
Caprine herpesvirus 1 (CpHV-1) as a potential candidate for oncolytic virotherapy.
Infections
Cardiac-specific overexpression of melanoma differentiation-associated gene-5 protects mice from lethal viral myocarditis.
Infections
Caspase -1, -3, -8 and antioxidant enzyme genes are key molecular effectors following Vibrio parahaemolyticus and Aeromonas veronii infection in fish leukocytes.
Infections
Caspase activation and specific cleavage of substrates after coxsackievirus B3-induced cytopathic effect in HeLa cells.
Infections
Caspase-3 activation and ERK phosphorylation during CVB3 infection of cells: influence of the coxsackievirus and adenovirus receptor and engineered variants.
Infections
Caspase-3 and -7 mediate apoptosis of human Chang's conjunctival cells induced by enterovirus 70.
Infections
Caspase-3 cleavage of Salmonella type III secreted effector protein SifA is required for localization of functional domains and bacterial dissemination.
Infections
Caspase-3 mediates the pathogenic effect of Yersinia pestis YopM in liver of C57BL/6 mice and contributes to YopM's function in spleen.
Infections
Caspase-3, a shrimp phosphorylated hemocytic protein is necessary to control YHV infection.
Infections
Caspase-3-dependent apoptosis in Escherichia coli-infected urothelium: involvement of inducible nitric oxide synthase.
Infections
Caspase-3-dependent reactivation of latent herpes simplex virus type 1 in sensory neuronal cultures.
Infections
Caspase-3-like proteases are activated by infection but are not required for replication of vesicular stomatitis virus.
Infections
Caspase-8 activity is part of the BeWo trophoblast cell defense mechanisms against Trypanosoma cruzi infection.
Infections
Caspase-8 and Apaf-1-independent caspase-9 activation in Sendai virus-infected cells.
Infections
Caspase-dependent apoptosis in fulminant hepatic failure induced by herpes simplex virus in mice.
Infections
Caspase-Mediated Cleavage of Human Cortactin during Influenza A Virus Infection Occurs in Its Actin-Binding Domains and Is Associated with Released Virus Titres.
Infections
Cell apoptosis regulated by interaction between viral gene alpha 3 and host heterogeneous nuclear ribonucleoprotein K facilitates bovine ephemeral fever virus replication.
Infections
Cell death, caspase activation, and HMGB1 release of porcine choroid plexus epithelial cells during Streptococcus suis infection in vitro.
Infections
Cellular Caspase-3 Contributes to EV-A71 2Apro-Mediated Down-Regulation of IFNAR1 at the Translation Level.
Infections
Chandipura Virus induces Neuronal Death through Fas-mediated Extrinsic Apoptotic Pathway.
Infections
Characterization of a Bombyx mori nucleopolyhedrovirus mutant lacking both fp25K and p35.
Infections
Characterization of an insecticidal toxin and pathogenicity of Pseudomonas taiwanensis against insects.
Infections
Characterization of antiproliferative and cytotoxic properties of the HSV-1 immediate-early ICPo protein.
Infections
Characterization of Apoptosis Pathways (Intrinsic and Extrinsic) in Lymphoid Tissues of Calves Inoculated with Non-cytopathic Bovine Viral Diarrhoea Virus Genotype-1.
Infections
Characterization of thymic involution induced by murine cytomegalovirus infection.
Infections
Chlamydia pneumoniae augments the oxidized low-density lipoprotein-induced death of mouse macrophages by a caspase-independent pathway.
Infections
Citral Attenuated Intestinal Inflammation Induced by Cronobacter sakazakii in Newborn Mice.
Infections
Cloning and characterization of a caspase gene from black tiger shrimp (Penaeus monodon)-infected with white spot syndrome virus (WSSV).
Infections
Combination gene therapy for glioblastoma involving herpes simplex virus vector-mediated codelivery of mutant IkappaBalpha and HSV thymidine kinase.
Infections
Comparative transcriptome analysis reveals PERP upregulated during Salmonella Enteritidis challenge in laying ducks.
Infections
Comparison of the host cells apoptosis induced by precocious strains and virulent strains of Eimeria tenella.
Infections
Conditional expression of anti-apoptotic protein p35 by Cre-mediated DNA recombination in cardiomyocytes from loxP-p35-transgenic mice.
Infections
Crimean-Congo haemorrhagic fever replication interplays with regulation mechanisms of apoptosis.
Infections
Critical Role of HAX-1 in Promoting Avian Influenza Virus Replication in Lung Epithelial Cells.
Infections
Cronobacter sakazakii ATCC 29544 Translocated Human Brain Microvascular Endothelial Cells via Endocytosis, Apoptosis Induction, and Disruption of Tight Junction.
Infections
CXCR2 signaling protects oligodendrocytes and restricts demyelination in a mouse model of viral-induced demyelination.
Infections
Cytosolic phospholipase A2 participates with TNF-alpha in the induction of apoptosis of human macrophages infected with Mycobacterium tuberculosis H37Ra.
Infections
Decreased apoptosis in the ileum and ileal Peyer's patches: a feature after infection with rabbit enteropathogenic Escherichia coli O103.
Infections
Delineation of the molecular mechanisms of Francisella tularensis-induced apoptosis in murine macrophages.
Infections
Dietary genistein supplementation improves intestinal mucosal barrier function in Escherichia coli O78-challenged broilers.
Infections
Dietary vitamin C deficiency depressed the gill physical barriers and immune barriers referring to Nrf2, apoptosis, MLCK, NF-?B and TOR signaling in grass carp (Ctenopharyngodon idella) under infection of Flavobacterium columnare.
Infections
Different expression of apoptotic proteins between HBV-infected and non-HBV-infected hepatocellular carcinoma.
Infections
Differential antiviral and anti-inflammatory mechanisms of the flavonoids biochanin A and baicalein in H5N1 influenza A virus-infected cells.
Infections
Differential caspase-3 expression in noncancerous, premalignant and cancer tissues of stomach and its clinical implication.
Infections
Differential gene expression profiling of Actinobacillus pleuropneumoniae during induction of primary alveolar macrophage apoptosis in piglets.
Infections
Distemper virus encephalitis exerts detrimental effects on hippocampal neurogenesis.
Infections
During Infection, Theiler's Virions Are Cleaved by Caspases and Disassembled into Pentamers.
Infections
Dysfunction of the PI3K-Akt-GSK-3 pathway is a common feature in cell culture and in vivo models of prion disease.
Infections
E1B 55-kDa deleted, Ad5/F35 fiber chimeric adenovirus, a potential oncolytic agent for B-lymphocytic malignancies.
Infections
Early Occurrence of Apoptosis in Lymphoid Tissues from Chickens Infected with Strains of Newcastle Disease Virus of Varying Virulence.
Infections
Edwardsiella piscicida type III protein EseJ suppresses apoptosis through down regulating type 1 fimbriae, which stimulate the cleavage of caspase-8.
Infections
Edwardsiella tarda invasion of fish cell lines and the activation of divergent cell death pathways.
Infections
Effects of dietary monocalcium phosphate supplementation on the anti-oxidative capacity, anti-bacteria function in immune organs of obscure puffer (Takifugu obscurus) after infection with Aeromonas hydrophila.
Infections
Effects of human cytomegalovirus infection on apoptosis and expression of apoptosis-regulating factors.
Infections
Effects of the PI3K/Akt signaling pathway on the apoptosis of early host cells infected with Eimeria tenella.
Infections
Eimeria acervulina Microneme Protein 3 Inhibits Apoptosis of the Chicken Duodenal Epithelial Cell by Targeting the Casitas B-Lineage Lymphoma Protein.
Infections
Emergence of cisplatin-resistant cells from the OVCAR-3 ovarian carcinoma cell line with p53 mutations, altered tumorigenicity, and increased apoptotic sensitivity to p53 gene replacement.
Infections
Encephalitozoon microsporidia modulates p53-mediated apoptosis in infected cells.
Infections
Enhancement of gemcitabine sensitivity in pancreatic cancer by co-regulation of dCK and p8 expression.
Infections
Enterotoxigenic Escherichia coli modulates host intestinal cell membrane asymmetry and metabolic activity.
Infections
Enterovirus 71 induces apoptosis by directly modulating the conformational activation of pro-apoptotic protein Bax.
Infections
Enterovirus 71 induces apoptosis of SH?SY5Y human neuroblastoma cells through stimulation of endogenous microRNA let-7b expression.
Infections
Enterovirus 71 suppresses interferon responses by blocking Janus kinase (JAK)/signal transducer and activator of transcription (STAT) signaling through inducing karyopherin-?1 degradation.
Infections
Epithelial intestinal cell apoptosis induced by Helicobacter pylori depends on expression of the cag pathogenicity island phenotype.
Infections
Equine arteritis virus induced cell death is associated with activation of the intrinsic apoptotic signalling pathway.
Infections
Evaluation of Photobiogoverning Role of Blue Light Irradiation on Viral Replication.
Infections
Exoenzyme S of Pseudomonas aeruginosa is not able to induce apoptosis when cells express activated proteins, such as Ras or protein kinase B/Akt.
Infections
Exoenzyme Y induces extracellular active caspase-7 accumulation independent from apoptosis: modulation of transmissible cytotoxicity.
Infections
FasL/Fas pathway is involved in dengue virus induced apoptosis of the vascular endothelial cells.
Infections
Gene expression pattern in human brain endothelial cells in response to Neisseria meningitidis.
Infections
Gene transfer of constitutively active caspase-3 induces apoptosis in a human hepatoma cell line.
Infections
Genes in the Salmonella pathogenicity island 2 and the Salmonella virulence plasmid are essential for Salmonella-induced apoptosis in intestinal epithelial cells.
Infections
Genetic susceptibility and caspase activation in mouse and human macrophages are distinct for Legionella longbeachae and L. pneumophila.
Infections
Heat shock cognate protein 70 gene is required for prevention of apoptosis induced by WSSV infection.
Infections
Helicobacter pylori infection induces oxidative stress and programmed cell death in human gastric epithelial cells.
Infections
Helicobacter pylori infection upregulates interleukin-18 production from gastric epithelial cells.
Infections
Hepatic histopathology and apoptosis in diet-induced-obese mice under Escherichia coli pneumonia.
Infections
Hepatitis C virus induced a novel apoptosis-like death of pancreatic beta cells through a caspase 3-dependent pathway.
Infections
Herpes simplex virus 1 inhibits apoptosis through a caspase-3-dependent pathway in primary cultures of cortical neuronal cells of fetal mice.
Infections
Herpes Simplex Virus Type 1 Neuronal Infection Elicits Cellular and Molecular Mechanisms of Neuroinflammation and Neurodegeneration in in vitro and in vivo Mice Models.
Infections
High-neurovirulence GDVII virus induces apoptosis in murine astrocytes through tumor necrosis factor (TNF)-receptor and TNF-related apoptosis-inducing ligand.
Infections
Hippocampal poly(ADP-Ribose) polymerase 1 and caspase 3 activation in neonatal bornavirus infection.
Infections
HSV-1 Infection Modulates the Radioresponse of a HPV16-positive Head and Neck Cancer Cell Line.
Infections
Human coronavirus-induced neuronal programmed cell death is cyclophilin d dependent and potentially caspase dispensable.
Infections
Human Cytomegalovirus Stimulates Monocyte-to-Macrophage Differentiation via the Temporal Regulation of Caspase 3.
Infections
Human Gut-On-A-Chip Supports Polarized Infection of Coxsackie B1 Virus In Vitro.
Infections
Human immunodeficiency virus type 1 replication inhibition by the bidentate iron chelators CP502 and CP511 is caused by proliferation inhibition and the onset of apoptosis.
Infections
Human parainfluenza virus type 1 C proteins are nonessential proteins that inhibit the host interferon and apoptotic responses and are required for efficient replication in nonhuman primates.
Infections
Human-induced pluripotent stem cell-derived macrophages and their immunological function in response to tuberculosis infection.
Infections
Identification and functional characterization of three caspases in Takifugu obscurus in response to bacterial infection.
Infections
Identification of NEEP21, encoding neuron-enriched endosomal protein of 21 kDa, as a transcriptional target of tumor suppressor p53.
Infections
Immunopathology of Fatal Human Variegated Squirrel Bornavirus 1 Encephalitis, Germany, 2011-2013.
Infections
Impact of caspase-1/11, -3, -7, or IL-1?/IL-18 deficiency on rabies virus-induced macrophage cell death and onset of disease.
Infections
Importin-? and exportin-5 are strong biomarkers of productive reoviral infection of cancer cells.
Infections
In vivo and in vitro assessment of host-parasite interaction between the parasitic copepod Brachiella thynni (Copepoda; Lernaeopodidae) and the farmed Atlantic bluefin tuna (Thunnus thynnus).
Infections
Incomplete activation of macrophage apoptosis during intracellular replication of Legionella pneumophila.
Infections
Increase of apoptosis in a murine model for severe pneumococcal pneumonia during influenza A virus infection.
Infections
Increased S-nitrosylation and proteasomal degradation of caspase-3 during infection contribute to the persistence of adherent invasive Escherichia coli (AIEC) in immune cells.
Infections
Induced apoptosis of chondrocytes by Porphyromonas gingivalis as a possible pathway for cartilage loss in rheumatoid arthritis.
Infections
Induction of a Cellular DNA Damage Response by Porcine Circovirus Type 2 Facilitates Viral Replication and Mediates Apoptotic Responses.
Infections
Induction of apoptosis in p16INK4A mutant cell lines by adenovirus-mediated overexpression of p16INK4A protein.
Infections
Induction of apoptosis in SSN-1cells by Snakehead Fish Vesiculovirus (SHVV) via Matrix protein dependent intrinsic pathway.
Infections
Induction of cell cycle arrest and apoptosis by BCG infection in cultured human bronchial airway epithelial cells.
Infections
Infection by Cx43 adenovirus increased chemotherapy sensitivity in human gastric cancer BGC-823 cells: not involving in induction of cell apoptosis.
Infections
Influence of COX-2 inhibition by rofecoxib on serum and tumor progastrin and gastrin levels and expression of PPARgamma and apoptosis-related proteins in gastric cancer patients.
Infections
Influence of cytochrome c on apoptosis induced by Anagrapha (Syngrapha) falcifera multiple nuclear polyhedrosis virus (AfMNPV) in insect Spodoptera litura cells.
Infections
Influenza a virus induced apoptosis: inhibition of DNA laddering & caspase-3 activity by zinc supplementation in cultured HeLa cells.
Infections
Influenza virus H1N1 induced apoptosis of mouse astrocytes and the effect on protein expression.
Infections
Inhibition of autophagy by 3-methyladenine restricts murine cytomegalovirus replication.
Infections
Inhibition of ICE-like proteases inhibits apoptosis and increases virus production during adenovirus infection.
Infections
Inhibitory Effect of Lentivirus-Mediated Gag-Caspase-8 on the Growth of HER-2-Overexpressing Primary Human Breast Cancer Cells.
Infections
Insights into regulatory molecules of intestinal epithelial cell turnover during experimental infection by Heterophyes heterophyes.
Infections
Insulin-like growth factor binding protein-3 inhibits the growth of non-small cell lung cancer.
Infections
Interferon regulatory factor 3 from sea perch (Lateolabrax japonicus) exerts antiviral function against nervous necrosis virus infection.
Infections
Intrahepatic infiltrating NK and CD8 T cells cause liver cell death in different phases of dengue virus infection.
Infections
Intrinsic apoptosis and proinflammatory cytokines regulated in human astrocytes infected with enterovirus 71.
Infections
Intrinsic, extrinsic and endoplasmic reticulum stress-induced apoptosis in RK13 cells infected with equine arteritis virus.
Infections
Invasion of HeLa cells by group B streptococcus requires the phosphoinositide-3-kinase signalling pathway and modulates phosphorylation of host-cell Akt and glycogen synthase kinase-3.
Infections
Involvement of caspase activation through release of cytochrome c from mitochondria in apoptotic cell death of macrophages infected with Actinobacillus actinomycetemcomitans.
Infections
Involvement of caspase-3 pathway in anti-apoptotic action of methionine enkephalin on CEMx174 cells in prolonged infection with simian immunodeficiency virus in vitro.
Infections
Involvement of caspases in apoptotic cell death of murine macrophages infected with Actinobacillus actinomycetemcomitans.
Infections
Involvement of PI 3 kinase/Akt-dependent Bad phosphorylation in Toxoplasma gondii-mediated inhibition of host cell apoptosis.
Infections
Involvement of the mitogen-activated protein kinase pathway in soft-shelled turtle iridovirus-induced apoptosis.
Infections
Involvement of the PI3K and ERK signaling pathways in largemouth bass virus-induced apoptosis and viral replication.
Infections
Japanese encephalitis virus NS2B-NS3 protease induces caspase 3 activation and mitochondria-mediated apoptosis in human medulloblastoma cells.
Infections
Lack of apoptosis in Listeria monocytogenes-infected thymocytes from mice fed with dietary lipids.
Infections
Lactobacillus acidophilus S-layer protein-mediated inhibition of PEDV-induced apoptosis of Vero cells.
Infections
Leishmania donovani infection activates Toll-like receptor 2, 4 expressions and Transforming growth factor-beta mediated apoptosis in renal tissues.
Infections
Leishmania infantum Induces Mild Unfolded Protein Response in Infected Macrophages.
Infections
Life as a Vector of Dengue Virus: The Antioxidant Strategy of Mosquito Cells to Survive Viral Infection.
Infections
Longitudinal changes in plasma Caspase-1 and Caspase-3 during the first 2 years of HIV-1 infection in CD4Low and CD4High patient groups.
Infections
Macrophage activation redirects yersinia-infected host cell death from apoptosis to caspase-1-dependent pyroptosis.
Infections
Magnolol protects Ctenopharyngodon idella kidney cells from apoptosis induced by grass carp reovirus.
Infections
Malarial infection develops mitochondrial pathology and mitochondrial oxidative stress to promote hepatocyte apoptosis.
Infections
Matrix metaloproteinase-2 and placentary dysfunction development in pregnancy with perinatal infections
Infections
Melatonin attenuates apoptotic liver damage in fulminant hepatic failure induced by the rabbit hemorrhagic disease virus.
Infections
Micropterus salmoides rhabdovirus (MSRV) infection induced apoptosis and activated interferon signaling pathway in largemouth bass skin cells.
Infections
MicroRNA regulation of viral immunity, latency, and carcinogenesis of selected tumor viruses and HIV.
Infections
mir-233 modulates the unfolded protein response in C. elegans during Pseudomonas aeruginosa infection.
Infections
Modified caspase-3 assay indicates correlation of caspase-3 activity with immunity of nonhuman primates to Yersinia pestis infection.
Infections
Modulation of apoptosis by caprine herpesvirus 1 infection in a neuronal cell line.
Infections
Modulation of caspases and their non-apoptotic functions by Legionella pneumophila.
Infections
Modulation of p53 cellular function and cell death by African swine fever virus.
Infections
Molecular and immune response characterizations of a novel AIF and cytochrome c in Litopenaeus vannamei defending against WSSV infection.
Infections
Molecular Targets and Mechanisms of Scutellariae radix-Coptidis rhizoma Drug Pair for the Treatment of Ulcerative Colitis Based on Network Pharmacology and Molecular Docking.
Infections
Morphine aggravates the apoptosis of simian immunodeficiency virus infected CEM x174 cells in the prolonged culture in vitro.
Infections
Morphofunctional characteristics of fetoplacental barrier of placental villi during pregnancy complicated by herpes-virus infection.
Infections
Morphological changes contribute to apoptotic cell death and are affected by caspase-3 and caspase-6 inhibitors during red sea bream iridovirus permissive replication.
Infections
Mouse cytomegalovirus M36 and M45 death suppressors cooperate to prevent inflammation resulting from antiviral programmed cell death pathways.
Infections
Multidrug-resistant tuberculosis (MDR-TB) strain infection in macaques results in high bacilli burdens in airways, driving broad innate/adaptive immune responses.
Infections
Murine polyomavirus infection of 3T6 mouse cells shows evidence of predominant necrosis as well as limited apoptosis.
Infections
Mycobacterium bovis Induces Endoplasmic Reticulum Stress Mediated-Apoptosis by Activating IRF3 in a Murine Macrophage Cell Line.
Infections
Mycobacterium tuberculosis infection causes different levels of apoptosis and necrosis in human macrophages and alveolar epithelial cells.
Infections
Mycobacterium tuberculosis promotes apoptosis in human neutrophils by activating caspase-3 and altering expression of Bax/Bcl-xL via an oxygen-dependent pathway.
Infections
Mycoplasma agalactiae Induces Cytopathic Effects in Infected Cells Cultured In Vitro.
Infections
Mycoplasma synoviae induces upregulation of apoptotic genes, secretion of nitric oxide and appearance of an apoptotic phenotype in infected chicken chondrocytes.
Infections
Necroptosis of Splenic Macrophages Induced by Streptococcus gallolyticus subsp. pasteurianus.
Infections
Netrin-1 restores cell injury and impaired angiogenesis in vascular endothelial cells upon high glucose by PI3K/AKT-eNOS.
Infections
NF-kappaB activation suppresses host cell apoptosis during Rickettsia rickettsii infection via regulatory effects on intracellular localization or levels of apoptogenic and anti-apoptotic proteins.
Infections
NFkappaB mediates apoptosis through transcriptional activation of Fas (CD95) in adenoviral hepatitis.
Infections
Nitric Oxide Causes Anoikis through Attenuation of E-Cadherin and Activation of Caspase-3 in Human Gastric Carcinoma AZ-521 Cells Infected with Mycoplasma hyorhinis.
Infections
NleH effectors interact with Bax inhibitor-1 to block apoptosis during enteropathogenic Escherichia coli infection.
Infections
Nuclear Envelope Disruption Involving Host Caspases Plays a Role in the Parvovirus Replication Cycle.
Infections
Nuclear factor kappa B protects against host cell apoptosis during Rickettsia rickettsii infection by inhibiting activation of apical and effector caspases and maintaining mitochondrial integrity.
Infections
Nutraceutical activators of AMPK/Sirt1 axis inhibit viral production and protect neurons from neurodegenerative events triggered during HSV-1 infection.
Infections
OMP31 of Brucella melitensis 16M impairs the apoptosis of macrophages triggered by TNF-?.
Infections
Oncolytic vesicular stomatitis virus induces apoptosis in U87 glioblastoma cells by a type II death receptor mechanism and induces cell death and tumor clearance in vivo.
Infections
Over-expression of C/EBP-alpha induces apoptosis in cultured rat hepatic stellate cells depending on p53 and peroxisome proliferator-activated receptor-gamma.
Infections
Overexpression of 4EBP1, p70S6K, Akt1 or Akt2 differentially promotes Coxsackievirus B3-induced apoptosis in HeLa cells.
Infections
Overexpression of interferon-gamma-inducible GTPase inhibits coxsackievirus B3-induced apoptosis through the activation of the phosphatidylinositol 3-kinase/Akt pathway and inhibition of viral replication.
Infections
Pathological Characterization Of IFNAR(-/-) Mice Infected With Bluetongue Virus Serotype 4.
Infections
PCV2 infection aggravates ochratoxin A-induced nephrotoxicity via autophagy involving p38 signaling pathway in vivo and in vitro.
Infections
Phosphoprotein Gene Contributes to the Enhanced Apoptosis Induced by Wild-Type Rabies Virus GD-SH-01 In Vitro.
Infections
Phosphorylation of p38 MAPK and its downstream targets in SARS coronavirus-infected cells.
Infections
Phosphorylation of the influenza A virus protein PB1-F2 by PKC is crucial for apoptosis promoting functions in monocytes.
Infections
Porcine parvovirus infection activates mitochondria-mediated apoptotic signaling pathway by inducing ROS accumulation.
Infections
Porcine reproductive and respiratory syndrome virus infection induces endoplasmic reticulum stress, facilitates virus replication, and contributes to autophagy and apoptosis.
Infections
Potent antitumor efficacy of XAF1 delivered by conditionally replicative adenovirus vector via caspase-independent apoptosis.
Infections
Potential mechanisms of Chinese Herbal Medicine that implicated in the treatment of COVID-19 related renal injury.
Infections
Prebiotics and phytogenics functional additives in low fish meal and fish oil based diets for European sea bass (Dicentrarchus labrax): Effects on stress and immune responses.
Infections
Prognostic markers of low-grade squamous intraepithelial lesions: the role of topoisomerase IIalpha and active caspase-3.
Infections
Protection against CD95-induced apoptosis by chlamydial infection at a mitochondrial step.
Infections
Protein kinase C-zeta is critical in pancreatitis-induced apoptosis of Kupffer cells.
Infections
Proteolysis of Pseudomonas exotoxin A within hepatic endosomes by cathepsins B and D produces fragments displaying in vitro ADP-ribosylating and apoptotic effects.
Infections
Proteolytic cleavage of the catalytic subunit of DNA-dependent protein kinase during poliovirus infection.
Infections
Rapid pathogen-induced apoptosis: a mechanism used by dendritic cells to limit intracellular replication of Legionella pneumophila.
Infections
Real-Time Induction of Macrophage Apoptosis, Pyroptosis, and Necroptosis by Enterococcus faecalis OG1RF and Two Root Canal Isolated Strains.
Infections
Recombinant adeno-associated virus-delivered hypoxia-inducible stanniocalcin-1 expression effectively inhibits hypoxia-induced cell apoptosis in cardiomyocytes.
Infections
Recombinant oncolytic Newcastle disease virus displays antitumor activities in anaplastic thyroid cancer cells.
Infections
Reovirus-associated reduction of microRNA-let-7d is related to the increased apoptotic death of cancer cells in clinical samples.
Infections
Repurposing of antiparasitic niclosamide to inhibit respiratory syncytial virus (RSV) replication.
Infections
Requirement of caspase-3 for efficient apoptosis induction and caspase-7 activation but not viral replication or cell rounding in cells infected with vesicular stomatitis virus.
Infections
Respiratory syncytial virus infection of human alveolar epithelial cells enhances interferon regulatory factor 1 and interleukin-1beta-converting enzyme gene expression but does not cause apoptosis.
Infections
Responses of murine and human macrophages to leptospiral infection: a study using comparative array analysis.
Infections
Restriction of H1N1 influenza virus infection by selenium nanoparticles loaded with ribavirin via resisting caspase-3 apoptotic pathway.
Infections
Role of the WWOX gene, encompassing fragile region FRA16D, in suppression of pancreatic carcinoma cells.
Infections
Rotavirus Non-Structural Protein-1 suppresses virus induced cellular apoptosis to facilitate viral growth by activating the cell-survival pathways during early stages of infection.
Infections
Salmonella typhimurium infection in the porcine intestine: evidence for caspase-3-dependent and -independent programmed cell death.
Infections
Schistosoma japonicum Infection Promotes the Response of Tfh Cells Through Down-Regulation of Caspase-3-Mediating Apoptosis.
Infections
Selective Deletion of CD8(+) Cells Upregulated by Caspases-1 via IL-18 in Mice Immunized with Major Outer Membrane Protein of Shigella dysenteriae 1 Following Infection.
Infections
Selenium Plays a Protective Role in Staphylococcus aureus-Induced Endometritis in the Uterine Tissue of Rats.
Infections
Severe acute respiratory syndrome coronavirus triggers apoptosis via protein kinase R but is resistant to its antiviral activity.
Infections
sHLA-G Involved in the Apoptosis of Decidual Natural Killer Cells Following Toxoplasma gondii Infection.
Infections
Siji Antiviral Mixture Protects against CA16 Induced Brain Injury through Inhibiting PERK/STAT3/NF-?B Pathway.
Infections
SipA Activation of Caspase-3 Is a Decisive Mediator of Host Cell Survival at Early Stages of Salmonella enterica Serovar Typhimurium Infection.
Infections
Snakehead vesiculovirus (SHVV) infection alters striped snakehead (Ophicephalus striatus) cells (SSN-1) glutamine metabolism and apoptosis pathways.
Infections
Stabilization of Nrf2 by tBHQ confers protection against oxidative stress-induced cell death in human neural stem cells.
Infections
Staphylococcus aureus Exploits the Host Apoptotic Pathway To Persist during Infection.
Infections
Streptococcus suis Serotype 2 Infection Causes Host Immunomodulation Through Induction of Thymic Atrophy.
Infections
STRUCTURE OF CRIMEAN-CONGO HAEMORRAGHIC FEVER VIRUS NUCLEOPROTEIN: SUPERHELICAL HOMO-OLIGOMERS AND THE ROLE OF CASPASE-3 CLEAVAGE.
Infections
Study of programmed cell death in bovine herpesvirus 1 infected MDBK cells and the possible role of nitric oxide in this process.
Infections
Substance P delays apoptosis, enhancing keratitis after Pseudomonas aeruginosa infection.
Infections
Suppression of IGF1R in Melanoma Cells by an Adenovirus-Mediated One-Step Knockdown System.
Infections
Survivin prevents apoptosis by binding to caspase-3 in astrocytes infected with the BeAn strain of Theiler's murine encephalomyelitis virus.
Infections
Syphilitic infection impairs immunity by inducing both apoptosis and pyroptosis of CD4+ and CD8+ T lymphocytes.
Infections
Systemic macrophage and neutrophil destruction by secondary necrosis induced by a bacterial exotoxin in a Gram-negative septicaemia.
Infections
Tau cleavage at D421 by caspase-3 is induced in neurons and astrocytes infected with herpes simplex virus type 1.
Infections
Telbivudine Reduces Parvovirus B19-Induced Apoptosis in Circulating Angiogenic Cells.
Infections
Temporary inhibition of neuronal apoptosis in Aujeszky's disease virus-infected swine.
Infections
The apicomplexan pathogen Neospora caninum inhibits host cell apoptosis in the absence of discernible NF-kappa B activation.
Infections
The ATF6 branch of unfolded protein response and apoptosis are activated to promote African swine fever virus infection.
Infections
The C-type lectin homologue gene (EP153R) of African swine fever virus inhibits apoptosis both in virus infection and in heterologous expression.
Infections
The effect of Vibrio alginolyticus infection on caspase-3 expression and activity in white shrimp Litopenaeus vannamei.
Infections
The excitatory amino acid transporter-2 induces apoptosis and decreases glioma growth in vitro and in vivo.
Infections
The Gastrointestinal Tract Is an Alternative Route for SARS-CoV-2 Infection in a Nonhuman Primate Model.
Infections
The intracellular bacterium Rickettsia rickettsii exerts an inhibitory effect on the apoptosis of tick cells.
Infections
The JAK/STAT3 signaling pathway mediates inhibition of host cell apoptosis by Chlamydia psittaci infection.
Infections
The latency-related gene encoded by bovine herpesvirus 1 can suppress caspase 3 and caspase 9 cleavage during productive infection.
Infections
The Leishmania surface protease GP63 cleaves multiple intracellular proteins and actively participates in p38 mitogen-activated protein kinase inactivation.
Infections
The Pannexin 1/Purinergic Receptor P2X4 Pathway Controls the Secretion of MicroRNA-Containing Exosomes by HCV-Infected Hepatocytes.
Infections
The quantitative and functional changes of NK cells in mice infected with Angiostrongylus cantonensis.
Infections
The receptor for the complement C3a anaphylatoxin (C3aR) provides host protection against Listeria monocytogenes-induced apoptosis.
Infections
The role of caspase 3 in the mud crab (Scylla paramamosain) after Vibrio parahaemolyticus infection.
Infections
The type I NADH dehydrogenase of Mycobacterium tuberculosis counters phagosomal NOX2 activity to inhibit TNF-alpha-mediated host cell apoptosis.
Infections
The type III secretion system of Vibrio alginolyticus induces rapid apoptosis, cell rounding and osmotic lysis of fish cells.
Infections
The vaccinia virus F1L protein interacts with the proapoptotic protein Bak and inhibits Bak activation.
Infections
The viral nucleocapsid protein of transmissible gastroenteritis coronavirus (TGEV) is cleaved by caspase-6 and -7 during TGEV-induced apoptosis.
Infections
Thiazolidinediones protect mouse pancreatic ?-cells directly from cytokine-induced cytotoxicity through PPAR?-dependent mechanisms.
Infections
Tissue apoptosis in mice infected with Leptospira interrogans serovar Icterohaemorrhagiae.
Infections
Toxoplasma gondii infection inhibits the mitochondrial apoptosis through induction of Bcl-2 and HSP70.
Infections
Toxoplasma gondii protects against H(2) O(2) -induced apoptosis in ARPE-19 cells through the transcriptional regulation of apoptotic elements and downregulation of the p38 MAPK pathway.
Infections
Triggering Ras signalling by intracellular Francisella tularensis through recruitment of PKC? and ?I to the SOS2/GrB2 complex is essential for bacterial proliferation in the cytosol.
Infections
Trypanosomiasis-induced B cell apoptosis results in loss of protective anti-parasite antibody responses and abolishment of vaccine-induced memory responses.
Infections
Tula hantavirus infection of Vero E6 cells induces apoptosis involving caspase 8 activation.
Infections
Tula orthohantavirus nucleocapsid protein is cleaved in infected cells and may sequester activated caspase-3 during persistent infection to suppress apoptosis.
Infections
Tumor suppressor in lung cancer-1 (TSLC1) mediated by dual-regulated oncolytic adenovirus exerts specific antitumor actions in a mouse model.
Infections
U20 Is Responsible for Human Herpesvirus 6B Inhibition of TNF Receptor-Dependent Signaling and Apoptosis.
Infections
Viral protein synthesis is required for Enterovirus 71 to induce apoptosis in human glioblastoma cells.
Infections
Virulence factors of Helicobacter pylori in Korean isolates do not influence proinflammatory cytokine gene expression and apoptosis in human gastric epithelial cells, nor do these factors influence the clinical outcome.
Infections
Zebra Fish Lacking Adaptive Immunity Acquire an Antiviral Alert State Characterized by Upregulated Gene Expression of Apoptosis, Multigene Families, and Interferon-Related Genes.
Infections
[Antagonism of baicalin on cell cyclical distribution and cell apoptosis in A549 cells infected with influenza A (H1N1) virus].
Infections
[Effect of Helicobacter pylori infection on proliferation and apoptosis in stomach antrum in smoking patients].
Infections
[Increased apoptosis and down-regulation of RhoA in HepG2 cells infected by Listeria monocytogenes].
Infections
[Recombinant adenovirus overexpressing nkx2.5 protects H9c2 cells against H2O2-induced apoptosis].
Infections
[Studies on the apoptosis of RK13 cells induced by rabbit hemorrhagic disease virus]
Infections
[The effect of caspase-3 inhibitor on the concentrations of serum inflammatory cytokines in sepsis related acute kidney injury induced by peritoneal cavity infection in mice.]
Infertility
BARD1 expression during spermatogenesis is associated with apoptosis and hormonally regulated.
Infertility
Evaluation of FAS and caspase-3 in the endometrial tissue of patients with idiopathic infertility and recurrent pregnancy loss.
Infertility
Expression of mRNAs for pro-and anti-apoptotic factors in granulosa cells and follicular fluid of women undergoing in vitro fertilization. A pilot study.
Infertility, Male
A Network Pharmacology Approach to Reveal the Underlying Mechanisms of Zuogui Yin in the Treatment of Male Infertility.
Inflammatory Bowel Diseases
Inflammation-induced Occludin Downregulation Limits Epithelial Apoptosis by Suppressing Caspase 3 Expression.
Inflammatory Bowel Diseases
miR-224 Is Significantly Upregulated and Targets Caspase-3 and Caspase-7 During Colorectal Carcinogenesis.
Influenza in Birds
Biochemical Variations in Cytolytic Activity of Ortho- and Paramyxoviruses in Human Lung Tumor Cell Culture.
Influenza, Human
Antiviral activity of a synthesized shikonin ester against influenza A (H1N1) virus and insights into its mechanism.
Influenza, Human
Bovine lactoferrin inhibits Influenza A virus induced programmed cell death in vitro.
Influenza, Human
Caspase 3 activation is essential for efficient influenza virus propagation.
Influenza, Human
Human influenza virus infection and apoptosis induction in human vascular endothelial cells.
Influenza, Human
Influenza a virus induced apoptosis: inhibition of DNA laddering & caspase-3 activity by zinc supplementation in cultured HeLa cells.
Influenza, Human
Influenza A virus-induced caspase-3 cleaves the histone deacetylase 6 in infected epithelial cells.
Influenza, Human
Influenza circulating strains in Argentina exhibit differential induction of cytotoxicity and caspase-3 in vitro.
Influenza, Human
Influenza virus infection induces translocation of apoptosis-inducing factor (AIF) in A549 cells: role of AIF in apoptosis and viral propagation.
Influenza, Human
Interleukin-24 inhibits influenza A virus replication in vitro through induction of toll-like receptor 3 dependent apoptosis.
Influenza, Human
Magnitude of influenza virus replication and cell damage is associated with interleukin-6 production in primary cultures of human tracheal epithelium.
Influenza, Human
Quinazolin-derived myeloperoxidase inhibitor suppresses influenza A virus-induced reactive oxygen species, pro-inflammatory mediators and improves cell survival.
Influenza, Human
Restriction of H1N1 influenza virus infection by selenium nanoparticles loaded with ribavirin via resisting caspase-3 apoptotic pathway.
Influenza, Human
Sulfatide regulates caspase-3-independent apoptosis of influenza A virus through viral PB1-F2 protein.
Influenza, Human
[Ability of the influenza viruses and their envelope proteins to stimulates endothelial cells apoptosis in vitro].
Influenza, Human
[Antagonism of baicalin on cell cyclical distribution and cell apoptosis in A549 cells infected with influenza A (H1N1) virus].
Insomnia, Fatal Familial
Expression of excitatory amino acid transporter-1 (EAAT-1) in brain macrophages and microglia of patients with prion diseases.
Insulin Resistance
Activation of caspase-3 is an initial step triggering accelerated muscle proteolysis in catabolic conditions.
Insulin Resistance
Autophagy in ovary and polycystic ovary syndrome: role, dispute and future perspective.
Insulin Resistance
Based on Network Pharmacology Tools to Investigate the Molecular Mechanism of Cordyceps sinensis on the Treatment of Diabetic Nephropathy.
Insulin Resistance
CTRP5 ameliorates palmitate-induced apoptosis and insulin resistance through activation of AMPK and fatty acid oxidation.
Insulin Resistance
Decreased rate of protein synthesis, caspase-3 activity, and ubiquitin-proteasome proteolysis in soleus muscles from growing rats fed a low-protein, high-carbohydrate diet.
Insulin Resistance
Gene Expression Profiling of Apoptotic Proteins in Circulating Peripheral Blood Mononuclear Cells in Type II Diabetes Mellitus and Modulation by Metformin.
Insulin Resistance
Higher insulin sensitivity in EDL muscle of rats fed a low-protein, high-carbohydrate diet inhibits the caspase-3 and ubiquitin-proteasome proteolytic systems but does not increase protein synthesis.
Insulin Resistance
Insulin resistance accelerates muscle protein degradation: Activation of the ubiquitin-proteasome pathway by defects in muscle cell signaling.
Insulin Resistance
Insulin resistance affects the cytoprotective effect of insulin in cardiomyocytes through an impairment of MAPK phosphatase-1 expression.
Insulin Resistance
Mechanisms stimulating muscle wasting in chronic kidney disease: the roles of the ubiquitin-proteasome system and myostatin.
Insulin Resistance
P7C3-A20, a neuroprotective agent, alleviates fatty liver by inducing FGF21/FGF1 in a LKB1/AMPK/CRTC2-dependent manner and shaping gut microbiota.
Insulin Resistance
Salidroside from Rhodiola wallichiana var. cholaensis reverses insulin resistance and stimulates the GLP-1 secretion by alleviating ROS-mediated activation of MAPKs signaling pathway and mitigating apoptosis.
Insulin Resistance
Study on the metabolism toxicity, susceptibility and mechanism of di-(2-ethylhexyl) phthalate on rat liver BRL cells with insulin resistance in vitro.
Insulinoma
Acute hypoxia induces apoptosis of pancreatic ?-cell by activation of the unfolded protein response and upregulation of CHOP.
Insulinoma
Caspase-3 Gene Silencing for Inhibiting Apoptosis in Insulinoma Cells and Human Islets.
Insulinoma
Caspase-3 is Involved in IFN-?- and TNF-?-Mediated MIN6 Cells Apoptosis via NF-?B/Bcl-2 Pathway.
Insulinoma
Cytokines activate caspase-3 in insulinoma cells of diabetes-prone NOD mice directly and via upregulation of Fas.
Insulinoma
Differences between amyloid toxicity in alpha and beta cells in human and mouse islets and the role of caspase-3.
Insulinoma
Group VIA Phospholipase A2 Mitigates Palmitate-Induced Beta Cell Mitochondrial Injury and Apoptosis.
Insulinoma
Islet neogenesis associated protein (INGAP) protects pancreatic ? cells from IL-1? and IFN?-induced apoptosis.
Insulinoma
Liquiritigenin prevents palmitate-induced beta-cell apoptosis via estrogen receptor-mediated AKT activation.
Insulinoma
PANDER-induced cell-death genetic networks in islets reveal central role for caspase-3 and cyclin-dependent kinase inhibitor 1A (p21).
Insulinoma
Photoactivation of hypericin decreases the viability of RINm5F insulinoma cells through reduction of JNK/ERK phosphorylation and elevation of caspase-9/caspase-3 cleavage and Bax-to-Bcl-2 ratio.
Insulinoma
Reg2 protects mouse insulinoma cells from streptozotocin-induced mitochondrial disruption and apoptosis.
Insulinoma
Testosterone reduces AGTR1 expression to prevent ?-cell and islet apoptosis from glucotoxicity.
Insulinoma
The imidazoline compound RX871024 promotes insulinoma cell death independent of AMP-activated protein kinase inhibition.
Insulinoma
Transmembrane TNF and IFNgamma induce caspase-independent death of primary mouse pancreatic beta cells.
Insulinoma
[Study on molecular mechanism of inhibitory effect of baicalin on proliferation of insulinoma cell line in rats]
Intervertebral Disc Degeneration
Caspase 3 as a therapeutic target for regulation of intervertebral disc degeneration.
Intervertebral Disc Degeneration
Caspase 3 silencing inhibits biomechanical overload-induced intervertebral disk degeneration.
Intervertebral Disc Degeneration
Caspase-3 knockout inhibits intervertebral disc degeneration related to injury but accelerates degeneration related to aging.
Intervertebral Disc Degeneration
Deregulated miR-155 promotes Fas-mediated apoptosis in human intervertebral disc degeneration by targeting FADD and caspase-3.
Intervertebral Disc Degeneration
Efficiency of dual siRNA-mediated gene therapy for intervertebral disc degeneration (IVDD).
Intervertebral Disc Degeneration
HIF1A Alleviates compression-induced apoptosis of nucleus pulposus derived stem cells via upregulating autophagy.
Intervertebral Disc Degeneration
Occurrence and regional distribution of apoptosis in scoliotic discs.
Intervertebral Disc Degeneration
Tension induces intervertebral disc degeneration via endoplasmic reticulum stress-mediated autophagy.
Intervertebral Disc Degeneration
The mechanism of Bushen Huoxue decoction in treating intervertebral disc degeneration based on network pharmacology.
Intervertebral Disc Degeneration
The occurrence and regional distribution of DR4 on herniated disc cells: a potential apoptosis pathway in lumbar intervertebral disc.
Intervertebral Disc Degeneration
[Expression of Bax and Caspase-3 and apoptosis in human lumbar intervertebral disc degeneration]
Intervertebral Disc Displacement
Associations of Caspase-3 gene polymorphism with lumbar disc herniation.
Intervertebral Disc Displacement
Biochemical and morphological changes in herniated human intervertebral disc.
Intracranial Aneurysm
Increased apoptosis and cysteinyl aspartate specific protease-3 gene expression in human intracranial aneurysm.
Intracranial Aneurysm
Study on the role of Cathepsin B and JNK signaling pathway in the development of cerebral aneurysm.
Intracranial Aneurysm
[The expression and role of Cathepin B in intracranial aneurysm wall]
Intracranial Hypertension
Assessment of the role of intracranial hypertension and stress on hippocampal cell apoptosis and hypothalamic-pituitary dysfunction after TBI.
Iron Deficiencies
Heart and iron deficiency anaemia in rats with renal insufficiency: the role of hepcidin.
Iron Overload
Ameliorating Iron Overload in Intestinal Tissue of Adult Male Rats: Quercetin vs Deferoxamine.
Iron Overload
Antiapoptotic effects of cannabidiol in an experimental model of cognitive decline induced by brain iron overload.
Iron Overload
Cannabidiol Normalizes Caspase 3, Synaptophysin, and Mitochondrial Fission Protein DNM1L Expression Levels in Rats with Brain Iron Overload: Implications for Neuroprotection.
Iron Overload
Icariin Protects Bone Marrow Mesenchymal Stem Cells Against Iron Overload Induced Dysfunction Through Mitochondrial Fusion and Fission, PI3K/AKT/mTOR and MAPK Pathways.
Iron Overload
Inhibition of iron overload-induced apoptosis and necrosis of bone marrow mesenchymal stem cells by melatonin.
Iron Overload
Iron-induced energy supply deficiency and mitochondrial fragmentation in neurons.
Iron Overload
Nobiletin Regulates ROS/ADMA/DDAHII/eNOS/NO Pathway and Alleviates Vascular Endothelium Injury by Iron Overload.
Ischemic Attack, Transient
Aminoguanidine inhibits caspase-3 and calpain activation without affecting microglial activation following neonatal transient cerebral ischemia.
Ischemic Attack, Transient
Cloning and characterization of rat caspase-9: implications for a role in mediating caspase-3 activation and hippocampal cell death after transient cerebral ischemia.
Ischemic Attack, Transient
Ginsenoside Rb1 regulates the expressions of brain-derived neurotrophic factor and caspase-3 and induces neurogenesis in rats with experimental cerebral ischemia.
Ischemic Attack, Transient
Intracellular Bax translocation after transient cerebral ischemia: implications for a role of the mitochondrial apoptotic signaling pathway in ischemic neuronal death.
Ischemic Attack, Transient
The effect of low-energy laser irradiation on apoptotic factors following experimentally induced transient cerebral ischemia.
Ischemic Stroke
A preparation of Ginkgo biloba L. leaves extract inhibits the apoptosis of hippocampal neurons in post-stroke mice via regulating the expression of Bax/Bcl-2 and Caspase-3.
Ischemic Stroke
Association Between a Polymorphism in CASP3 and CASP9 Genes and Ischemic Stroke.
Ischemic Stroke
CD137 Ligand-CD137 Interaction is Required For Inflammasome-Associated Brain Injury Following Ischemic Stroke.
Ischemic Stroke
Curcumin prevents reperfusion injury following ischemic stroke in rats via inhibition of NF??B, ICAM-1, MMP-9 and caspase-3 expression.
Ischemic Stroke
Current Synthesis and Systematic Review of Main Effects of Calf Blood Deproteinized Medicine (Actovegin®) in Ischemic Stroke.
Ischemic Stroke
Effects of microRNA-21 and microRNA-24 inhibitors on neuronal apoptosis in ischemic stroke.
Ischemic Stroke
Electroacupuncture Alleviated Neuronal Apoptosis Following Ischemic Stroke in Rats via Midkine and ERK/JNK/p38 Signaling Pathway.
Ischemic Stroke
Ergostatrien-7,9(11),22-trien-3?-ol from Antrodia camphorata ameliorates ischemic stroke brain injury via downregulation of p65NF-?-B and caspase 3, and activation of Akt/GSK3/catenin-associated neurogenesis.
Ischemic Stroke
FADD (Fas-Associated Protein With Death Domain), Caspase-3, and Caspase-8 and Incidence of Ischemic Stroke.
Ischemic Stroke
Granulocyte colony-stimulating factor and stromal cell-derived factor-1 combination therapy: A more effective treatment for cerebral ischemic stroke.
Ischemic Stroke
Inhibition of microRNA-9-5p and microRNA-128-3p can inhibit ischemic stroke-related cell death in vitro and in vivo.
Ischemic Stroke
Lentiviral-mediated silencing of mast cell-expressed membrane protein 1 promotes angiogenesis of rats with cerebral ischemic stroke.
Ischemic Stroke
LncRNA SNHG6 functions as a ceRNA to regulate neuronal cell apoptosis by modulating miR-181c-5p/BIM signalling in ischaemic stroke.
Ischemic Stroke
Maternal hypoxia increases hippocampal cell susceptibility to ischemia after middle cerebral artery occlusion in rat offspring.
Ischemic Stroke
Memantine attenuates cell apoptosis by suppressing the calpain-caspase-3 pathway in an experimental model of ischemic stroke.
Ischemic Stroke
MicroRNA-378 Alleviates Cerebral Ischemic Injury by Negatively Regulating Apoptosis Executioner Caspase-3.
Ischemic Stroke
Mild hypothermia modulates the expression of nestin and caspase-3 in the sub-granular zone and improves neurological outcomes in rats with ischemic stroke.
Ischemic Stroke
MiR-195 alleviates oxygen-glucose deprivation/reperfusion-induced cell apoptosis via inhibition of IKK?-mediated NF-?B pathway.
Ischemic Stroke
Mutant ubiquitin-mediated beta-secretase stability via activation of caspase-3 is related to beta-amyloid accumulation in ischemic striatum in rats.
Ischemic Stroke
Pien-Tze-Huang protects cerebral ischemic injury by inhibiting neuronal apoptosis in acute ischemic stroke rats.
Ischemic Stroke
Possible Involvement of PTEN Signaling Pathway in the Anti-apoptotic Effect of Electroacupuncture Following Ischemic Stroke in Rats.
Ischemic Stroke
Purinergic 2X7 receptor/NLRP3 pathway triggers neuronal apoptosis after ischemic stroke in the mouse.
Ischemic Stroke
Serum Caspase-3 Levels and Early Mortality of Patients with Malignant Middle Cerebral Artery Infarction.
Ischemic Stroke
Spatio-temporal activation of caspase-8 in myeloid cells upon ischemic stroke.
Ischemic Stroke
TDAG8 activation attenuates cerebral ischaemia-reperfusion injury via Akt signalling in rats.
Ischemic Stroke
Uric Acid Neuroprotection Associated to IL-6/STAT3 Signaling Pathway Activation in Rat Ischemic Stroke.
Keloid
A Selenium-Enriched Ziyang Green Tea Polysaccharide Induces Bax-Dependent Mitochondrial Apoptosis and Inhibits TGF-?1-Stimulated Collagen Expression in Human Keloid Fibroblasts via NG2 Inactivation.
Keloid
Enhanced expression of caspase-3 in hypertrophic scars and keloid: induction of caspase-3 and apoptosis in keloid fibroblasts in vitro.
Keloid
Interleukin-18 system plays an important role in keloid pathogenesis via epithelial-mesenchymal interactions.
Keloid
Long non-coding RNA CACNA1G-AS1 promotes proliferation and invasion and inhibits apoptosis by regulating expression of miR-205 in human keloid fibroblasts.
Keloid
Phenalen-1-one-mediated photodynamic therapy inhibits keloid graft progression by reducing vessel formation and promoting fibroblast apoptosis.
Keloid
Topical application of imiquimod 5% cream to keloids alters expression genes associated with apoptosis.
Keloid
Triamcinolone Acetonide Suppresses Keloid Formation Through Enhancing Apoptosis in a Nude Mouse Model.
Keratoacanthoma
Expression of apoptotic and cell proliferation regulatory proteins in keratoacanthomas and squamous cell carcinomas of the skin.
Keratoacanthoma
Surgical removal of the parametrial fat pads stimulates apoptosis and inhibits UVB-induced carcinogenesis in mice fed a high-fat diet.
Ketosis
Oxidative stress, NF-?B signaling, NLRP3 inflammasome, and caspase apoptotic pathways are activated in mammary gland of ketotic Holstein cows.
Kidney Diseases
The Antioxidative Role of Natural Compounds from a Green Coconut Mesocarp Undeniably Contributes to Control Diabetic Complications as Evidenced by the Associated Genes and Biochemical Indexes.
Kidney Failure, Chronic
Activation of caspase-3 in the skeletal muscle during haemodialysis.
Kidney Neoplasms
Betulinic acid induces apoptosis and inhibits metastasis of human renal carcinoma cells in vitro and in vivo.
Kidney Neoplasms
Development of pyridazine derivatives as potential EGFR inhibitors and apoptosis inducers: Design, synthesis, anticancer evaluation, and molecular modeling studies.
Kidney Neoplasms
Long noncoding RNA PVT1 inhibits renal cancer cell apoptosis by up-regulating Mcl-1.
Kidney Neoplasms
Overexpression of COPS3 promotes clear cell renal cell carcinoma progression via regulation of Phospho-AKT(Thr308), Cyclin D1 and Caspase-3.
Laryngeal Neoplasms
Cilengitide, a small molecule antagonist, targeted to integrin ?? inhibits proliferation and induces apoptosis of laryngeal cancer cells in vitro.
Laryngeal Neoplasms
[Apoptosis mechanism of taxol combined with resveratrol on human laryngeal carcinoma Hep-2 cells].
Latent Infection
Granzymes and caspase 3 play important roles in control of gammaherpesvirus latency.
Latent Infection
Stable expression of human immunodeficiency virus type 1 Nef confers resistance against Fas-mediated apoptosis.
Leiomyoma
1,25-Dihydroxyvitamin D3 Treatment Shrinks Uterine Leiomyoma Tumors in the Eker Rat Model.
Leiomyoma
A novel selective progesterone receptor modulator asoprisnil (J867) inhibits proliferation and induces apoptosis in cultured human uterine leiomyoma cells in the absence of comparable effects on myometrial cells.
Leiomyoma
Changes in proliferating and apoptotic markers of leiomyoma following treatment with a selective progesterone receptor modulator or gonadotropin-releasing hormone agonist.
Leiomyoma
Comparative effects of SPRM asoprisnil (J867) on proliferation, apoptosis, and the expression of growth factors in cultured uterine leiomyoma cells and normal myometrial cells.
Leiomyoma
Effect of a selective progesterone receptor modulator on induction of apoptosis in uterine fibroids in vivo.
Leiomyoma
Fas and its ligand, caspases, and bcl-2 expression in gonadotropin-releasing hormone agonist-treated uterine leiomyoma.
Leiomyoma
Gene therapy of uterine leiomyomas: adenovirus-mediated expression of dominant negative estrogen receptor inhibits tumor growth in nude mice.
Leiomyoma
Novel effects of simvastatin on uterine fibroid tumors: in vitro and patient-derived xenograft mouse model study.
Leiomyoma
Progesterone receptor modulator CDB-2914 down-regulates proliferative cell nuclear antigen and Bcl-2 protein expression and up-regulates caspase-3 and poly(adenosine 5'-diphosphate-ribose) polymerase expression in cultured human uterine leiomyoma cells.
Leiomyoma
Simvastatin, at clinically relevant concentrations, affects human uterine leiomyoma growth and extracellular matrix production.
Leiomyosarcoma
The histone deacetylase inhibitor vorinostat selectively sensitizes fibrosarcoma cells to chemotherapy.
Leishmaniasis
Leishmania infantum Induces Mild Unfolded Protein Response in Infected Macrophages.
Leishmaniasis, Visceral
Leishmania donovani infection activates Toll-like receptor 2, 4 expressions and Transforming growth factor-beta mediated apoptosis in renal tissues.
Leptospirosis
Severe Leptospirosis Features in the Spleen Indicate Cellular Immunosuppression Similar to That Found in Septic Shock.
Leukemia
14-Deoxy-11,12-didehydroandrographolide inhibits proliferation and induces GSH-dependent cell death of human promonocytic leukemic cells.
Leukemia
2-Chloro-2'-deoxyadenosine-induced apoptosis in T leukemia cells is mediated via a caspase-3-dependent mitochondrial feedback amplification loop.
Leukemia
23-Hydroxyursolic Acid Isolated from the Stem Bark of Cussonia bancoensis Induces Apoptosis through Fas/Caspase-8-Dependent Pathway in HL-60 Human Promyelocytic Leukemia Cells.
Leukemia
3,5-bis(Benzylidene)-1-[3-(2-hydroxyethylthio)propanoyl]-piperidin-4-ones:A novel cluster of potent tumour-selective cytotoxins.
Leukemia
4-Acetyl-12,13-epoxyl-9-trichothecene-3,15-diol isolated from the fruiting bodies of Isariajaponica Yasuda induces apoptosis of human leukemia cells (HL-60).
Leukemia
5-Fluorouracil enhances apoptosis sensitivity of T lymphocytes mediated by CD3 epsilon.
Leukemia
A new pyridazinone exhibits potent cytotoxicity on human cancer cells via apoptosis and poly-ubiquitinated protein accumulation.
Leukemia
A novel synthesized 3', 5'-diprenylated chalcone mediates the proliferation of human leukemia cells by regulating apoptosis and autophagy pathways.
Leukemia
A novel therapeutic strategy against monocytic leukemia with deoxyadenosine analogs and adenosine deaminase inhibitors.
Leukemia
A strong glutathione S-transferase inhibitor overcomes the P-glycoprotein-mediated resistance in tumor cells. 6-(7-Nitro-2,1,3-benzoxadiazol-4-ylthio)hexanol (NBDHEX) triggers a caspase-dependent apoptosis in MDR1-expressing leukemia cells.
Leukemia
A112, a tamibarotene dimethylaminoethyl ester, may inhibit human leukemia cell growth more potently than tamibarotene.
Leukemia
Aloe-emodin induced in vitro G2/M arrest of cell cycle in human promyelocytic leukemia HL-60 cells.
Leukemia
Alterations in mRNA expression of apoptosis-related genes BCL2, BAX, FAS, caspase-3, and the novel member BCL2L12 after treatment of human leukemic cell line HL60 with the antineoplastic agent etoposide.
Leukemia
Ampelopsin Inhibits Cell Proliferation and Induces Apoptosis in HL60 and K562 Leukemia Cells by Downregulating AKT and NF-?B Signaling Pathways.
Leukemia
Antiapoptotic signaling via MCL1 confers resistance to caspase-3-mediated apoptotic cell death in the pregnant human uterine myocyte.
Leukemia
Antileukemic effects of piperlongumine and alpha lipoic acid combination on Jurkat, MEC1 and NB4 cells in vitro.
Leukemia
Antileukemic potency of CD19-specific T cells against chemoresistant pediatric acute lymphoblastic leukemia.
Leukemia
Antitumor activity and mechanism of action of the iron chelator, Dp44mT, against leukemic cells.
Leukemia
Antitumor effect of beta2-microglobulin in leukemic cell-bearing mice via apoptosis-inducing activity: activation of caspase-3 and nuclear factor-kappaB.
Leukemia
Antitumor effects of celecoxib on K562 leukemia cells are mediated by cell-cycle arrest, caspase-3 activation, and downregulation of Cox-2 expression and are synergistic with hydroxyurea or imatinib.
Leukemia
Apoptosis induced by protein phosphatase 2A (PP2A) inhibition in T leukemia cells is negatively regulated by PP2A-associated p38 mitogen-activated protein kinase.
Leukemia
Apoptosis Induction of Armeniacae Semen Extractin Human Acute Leukemia (NALM-6 and KG-1) Cells.
Leukemia
Apoptosis induction of human leukemia cells by Streptomyces sp. SY-103 metabolites through activation of caspase-3 and inactivation of Akt.
Leukemia
Apoptosis of human leukemia HL-60 cells and murine leukemia WEHI-3 cells induced by berberine through the activation of caspase-3.
Leukemia
Apoptosis of Leukemia Cells by Ocimum basilicum Fractions Following TNF alpha Induced Activation of JNK and Caspase 3.
Leukemia
Arsenic trioxide-induced apoptosis and differentiation are associated respectively with mitochondrial transmembrane potential collapse and retinoic acid signaling pathways in acute promyelocytic leukemia.
Leukemia
Association of high proliferation in adult T-cell leukemia cells with apoptosis, and expression of p53 protein in acute type ATL.
Leukemia
Auraptene Induces Apoptosis via Myeloid Cell Leukemia 1-Mediated Activation of Caspases in PC3 and DU145 Prostate Cancer Cells.
Leukemia
Baicalein induced in vitro apoptosis undergo caspases activity in human promyelocytic leukemia HL-60 cells.
Leukemia
BCR/ABL inhibits mismatch repair to protect from apoptosis and induce point mutations.
Leukemia
Berberine Induces Apoptotic Cell Death via Activation of Caspase-3 and -8 in HL-60 Human Leukemia Cells: Nuclear Localization and Structure-Activity Relationships.
Leukemia
beta-Lapachone (LAPA) Decreases Cell Viability and Telomerase Activity in Leukemia Cells: Suppression of Telomerase Activity by LAPA.
Leukemia
Beta2-microglobulin induces caspase-dependent apoptosis in the CCRF-HSB-2 human leukemia cell line independently of the caspase-3, -8 and -9 pathways but through increased reactive oxygen species.
Leukemia
Bovine lactoferricin selectively induces apoptosis in human leukemia and carcinoma cell lines.
Leukemia
Breaking chemoresistance and radioresistance with [213Bi]anti-CD45 antibodies in leukemia cells.
Leukemia
Butyrate regulates the expression of inflammatory and chemotactic cytokines in human acute leukemic cells during apoptosis.
Leukemia
cAMP protects acute promyelocytic leukemia cells from arsenic trioxide-induced caspase-3 activation and apoptosis.
Leukemia
Caspase-1 and -3 Inhibiting Drimane Sesquiterpenoids from the Extremophilic Fungus Penicillium solitum.
Leukemia
Caspase-3 activation is an early event and initiates apoptotic damage in a human leukemia cell line.
Leukemia
Caspase-3 antisense oligodeoxynucleotides inhibit apoptosis in gamma-irradiated human leukemia HL-60 cells.
Leukemia
Caspase-3 controls AML1-ETO-driven leukemogenesis via autophagy modulation in a ULK1 dependent manner.
Leukemia
Caspase-3, myogenic transcription factors and cell cycle inhibitors are regulated by leukemia inhibitory factor to mediate inhibition of myogenic differentiation.
Leukemia
Celastrol and an EGCG pro-drug exhibit potent chemosensitizing activity in human leukemia cells.
Leukemia
Chlorogenic acid induces apoptotic cell death in U937 leukemia cells through caspase- and mitochondria-dependent pathways.
Leukemia
Chromene induces apoptosis via caspase-3 activation in human leukemia HL-60 cells.
Leukemia
Clofilium, a potassium channel blocker, induces apoptosis of human promyelocytic leukemia (HL-60) cells via Bcl-2-insensitive activation of caspase-3.
Leukemia
Coadministration of histone deacetylase inhibitors and perifosine synergistically induces apoptosis in human leukemia cells through Akt and ERK1/2 inactivation and the generation of ceramide and reactive oxygen species.
Leukemia
Combination of Fludarabine and Imatinib Induces Apoptosis Synergistically Through Loss of Mitochondrial Membrane Potential and Increases in Caspase-3 Enzyme Activity in Human K562 Chronic Myleloid Leukemia Cells.
Leukemia
Compound K induced apoptosis via endoplasmic reticulum Ca2+ release through ryanodine receptor in human lung cancer cells.
Leukemia
CPP32 activation during dolichyl phosphate-induced apoptosis in U937 leukemia cells.
Leukemia
Cross-species withdrawal of MCL1 facilitates postpartum uterine involution in both the mouse and baboon.
Leukemia
Crystal Structures and Human Leukemia Cell Apoptosis Inducible Activities of Parthenolide Analogues Isolated from Piptocoma rufescens.
Leukemia
Curcumin Induces Apoptosis in Pre-B Acute Lymphoblastic Leukemia Cell Lines Via PARP-1 Cleavage.
Leukemia
Curcumin-induced cell cycle arrest and apoptosis in human acute promyelocytic leukemia HL-60 cells via MMP changes and caspase-3 activation.
Leukemia
Cytochathiazines A-C: Three Merocytochalasans with a 2 H-1,4-Thiazine Functionality from Coculture of Chaetomium globosum and Aspergillus flavipes.
Leukemia
Cytochrome c-related caspase-3 activation determines treatment response and relapse in childhood precursor B-cell ALL.
Leukemia
Cytoskeletal disruption accelerates caspase-3 activation and alters the intracellular membrane reorganization in DNA damage-induced apoptosis.
Leukemia
Cytotoxic and apoptotic effects of prenylflavonoid artonin B in human acute lymphoblastic leukemia cells.
Leukemia
Cytotoxic components from the leaves of Erythrophleum fordii induce human acute leukemia cell apoptosis through caspase 3 activation and PARP cleavage.
Leukemia
Cytotoxic effect of natural trans-resveratrol obtained from elicited Vitis vinifera cell cultures on three cancer cell lines.
Leukemia
Cytotoxic synergy between the multikinase inhibitor sorafenib and the proteasome inhibitor bortezomib in vitro: induction of apoptosis through Akt and c-Jun NH2-terminal kinase pathways.
Leukemia
Cytotoxicity of Gymnopilus purpureosquamulosus extracts on hematologic malignant cells through activation of the SAPK/JNK signaling pathway.
Leukemia
Dehydrocostus lactone enhances tumor necrosis factor-alpha-induced apoptosis of human leukemia HL-60 cells.
Leukemia
Delphinidin 3-sambubioside, a Hibiscus anthocyanin, induces apoptosis in human leukemia cells through reactive oxygen species-mediated mitochondrial pathway.
Leukemia
Dietary docosahexaenoic acid decreased lipid accumulation via inducing adipocytes apoptosis of grass carp, Ctenopharygodon idella.
Leukemia
Dietary flavonoids as proteasome inhibitors and apoptosis inducers in human leukemia cells.
Leukemia
Differential responses of proliferative and non-proliferative leukemia cells to oxidative stress.
Leukemia
Down-regulation of telomerase activity and activation of caspase-3 are responsible for tanshinone I-induced apoptosis in monocyte leukemia cells in vitro.
Leukemia
Downregulation of cyclooxygenase-2 expression and activation of caspase-3 are involved in peroxisome proliferator-activated receptor-gamma agonists induced apoptosis in human monocyte leukemia cells in vitro.
Leukemia
Doxycycline induces apoptosis by way of caspase-3 activation with inhibition of matrix metalloproteinase in human T-lymphoblastic leukemia CCRF-CEM cells.
Leukemia
Effect of dimethyl sulfides on the induction of apoptosis in human leukemia Jurkat cells and HL-60 cells.
Leukemia
Effect of resveratrol on high glucose-induced stress in human leukemia K562 cells.
Leukemia
Effects of glycolic acid on the induction of apoptosis via caspase-3 activation in human leukemia cell line (HL-60).
Leukemia
Enhancing therapeutic efficacy of oncolytic vaccinia virus armed with Beclin-1, an autophagic Gene in leukemia and myeloma.
Leukemia
EPA plays multiple roles in regulating lipid accumulation of grass carp Ctenopharyngodon idella adipose tissue in vitro and in vivo.
Leukemia
Epicochalasines?A and B: Two Bioactive Merocytochalasans Bearing Caged Epicoccine Dimer Units from Aspergillus flavipes.
Leukemia
Failure to activate caspase 3 in phorbol ester-resistant leukemia cells is associated with resistance to apoptotic cell death.
Leukemia
Fas signaling and blockade of Bcr-Abl kinase induce apoptotic Hrk protein via DREAM inhibition in human leukemia cells.
Leukemia
Genistein selectively potentiates arsenic trioxide-induced apoptosis in human leukemia cells via reactive oxygen species generation and activation of reactive oxygen species-inducible protein kinases (p38-MAPK, AMPK).
Leukemia
Geranylgeraniol potently induces caspase-3-like activity during apoptosis in human leukemia U937 cells.
Leukemia
Glucocorticoid-induced apoptotic pathways in eosinophils: comparison with glucocorticoid-sensitive leukemia cells.
Leukemia
Glucose starvation induces apoptosis in a model of acute T leukemia dependent on caspase-3 and apoptosis-inducing factor: a therapeutic strategy.
Leukemia
Glycogen synthase kinase-3? inactivation is an intracellular marker and regulator for endotoxemic neutrophilia.
Leukemia
Homoharringtonine acts synergistically with SG235-TRAIL, a conditionally replicating adenovirus, in human leukemia cell lines.
Leukemia
Human monocytoid leukemia cells are highly sensitive to apoptosis induced by 2'-deoxycoformycin and 2'-deoxyadenosine: association with dATP-dependent activation of caspase-3.
Leukemia
Human T cell leukemia cell death by apoptosis-inducing nucleosides from CD57(+) HLA-DR(bright) natural suppressor cell line.
Leukemia
Hyperforin a constituent of St John's wort (Hypericum perforatum L.) extract induces apoptosis by triggering activation of caspases and with hypericin synergistically exerts cytotoxicity towards human malignant cell lines.
Leukemia
Hyperisampsins H-M, Cytotoxic Polycyclic Polyprenylated Acylphloroglucinols from Hypericum sampsonii.
Leukemia
Identification of deficient mitochondrial signaling in apoptosis resistant leukemia cells by flow cytometric analysis of intracellular cytochrome c, caspase-3 and apoptosis.
Leukemia
Immunolocalization of the ICE/Ced-3-family protease, CPP32 (Caspase-3), in non-Hodgkin's lymphomas, chronic lymphocytic leukemias, and reactive lymph nodes.
Leukemia
Implication of intracellular ROS formation, caspase-3 activation and Egr-1 induction in platycodon D-induced apoptosis of U937 human leukemia cells.
Leukemia
In vitro antitumor properties of a novel cyclin-dependent kinase inhibitor, P276-00.
Leukemia
Inactivation of PI3k/Akt signaling pathway and activation of caspase-3 are involved in tanshinone I-induced apoptosis in myeloid leukemia cells in vitro.
Leukemia
Inactive caspase 3 activates Akt in human leukemia cells susceptible or resistant to apoptosis induced by phorbol ester.
Leukemia
Induction of apoptosis by 4-acetyl-12,13-epoxyl-9-trichothecene-3,15-diol from Isaria japonica Yasuda through intracellular reactive oxygen species formation and caspase-3 activation in human leukemia HL-60 cells.
Leukemia
Induction of apoptosis by Cordyceps militaris through activation of caspase-3 in leukemia HL-60 cells.
Leukemia
Induction of apoptosis by diallyl disulfide through activation of caspase-3 in human leukemia HL-60 cells.
Leukemia
Induction of apoptosis by KI0477959 through activation of caspase-3 in human leukemia cell line, HL-60 cells.
Leukemia
Induction of apoptosis by Korean medicine Gagam-whanglyun-haedoktang through activation of caspase-3 in human leukemia cell line, HL-60 cells.
Leukemia
Induction of apoptosis by penta-O-galloyl-beta-D-glucose through activation of caspase-3 in human leukemia HL-60 cells.
Leukemia
Induction of apoptosis in human acute leukemia Jurkat T cells by Albizzia julibrissin extract is mediated via mitochondria-dependent caspase-3 activation.
Leukemia
Induction of apoptosis in human cancer cells by TZT-1027, an antimicrotubule agent.
Leukemia
Induction of apoptosis in human promyelocytic leukemia cells by a natural trachylobane diterpene.
Leukemia
Induction of apoptosis through the activation of SAPK/JNK followed by the expression of death receptor Fas in X-irradiated cells.
Leukemia
Induction of caspase 3 activity, bcl-2 bax and p65 gene expression modulation in human acute promyelocytic leukemia HL-60 cells by doxorubicin with amifostine.
Leukemia
Induction of caspase 3 and modulation of some apoptotic genes in human acute promyelocytic leukemia HL-60 cells by carboplatin with amifostine.
Leukemia
Induction of G2/M arrest, endoreduplication, and apoptosis by actin depolymerization agent pextenotoxin-2 in human leukemia cells, involving activation of ERK and JNK.
Leukemia
Induction of G2/M phase arrest and apoptosis of human leukemia cells by potent antitumor triazoloacridinone C-1305.
Leukemia
Inhibition of nitric-oxide-mediated apoptosis in Jurkat leukemia cells despite cytochrome c release.
Leukemia
Interactive effects of histone deacetylase inhibitors and TRAIL on apoptosis in human leukemia cells: involvement of both death receptor and mitochondrial pathways.
Leukemia
Interleukin-24 inhibits influenza A virus replication in vitro through induction of toll-like receptor 3 dependent apoptosis.
Leukemia
Involvement of Bax, Bcl-2, Ca2+ and caspase-3 in capsaicin-induced apoptosis of human leukemia HL-60 cells.
Leukemia
Involvement of caspase-3 activation in squamocin-induced apoptosis in leukemia cell line HL-60.
Leukemia
Ionomycin inhibits Jurkat T cell behaviors in the presence of phorbol-12,13-dibutyrate.
Leukemia
LC3B upregulation by NANOG promotes immune resistance and stem-like property through hyperactivation of EGFR signaling in immune-refractory tumor cells.
Leukemia
Lentiviral vector-mediated RNA interference targeted against prohibitin inhibits apoptosis of the retinoic acid-resistant acute promyelocytic leukemia cell line NB4-R1.
Leukemia
Loperamide, an antidiarrheal agent, induces apoptosis and DNA damage in leukemia cells.
Leukemia
Low-dose ionizing irradiation triggers a 53BP1 response to DNA double strand breaks in mouse spermatogonial stem cells.
Leukemia
Lunasin, with an arginine-glycine-aspartic acid motif, causes apoptosis to L1210 leukemia cells by activation of caspase-3.
Leukemia
Mechanism of activation of caspase cascade during beta-carotene-induced apoptosis in human tumor cells.
Leukemia
Mechanism of UV-induced apoptosis in human leukemia cells: roles of Ca2+/Mg(2+)-dependent endonuclease, caspase-3, and stress-activated protein kinases.
Leukemia
Melatonin promotes puromycin-induced apoptosis with activation of caspase-3 and 5'-adenosine monophosphate-activated kinase-alpha in human leukemia HL-60 cells.
Leukemia
Mercuric chloride induces apoptosis via a mitochondrial-dependent pathway in human leukemia cells.
Leukemia
Methadone, commonly used as maintenance medication for outpatient treatment of opioid dependence, kills leukemia cells and overcomes chemoresistance.
Leukemia
Methylene chloride fraction of Scutellaria barbata induces apoptosis in human U937 leukemia cells via the mitochondrial signaling pathway.
Leukemia
MiR-486-5p inhibits the proliferation of leukemia cells and induces apoptosis through targeting FOXO1.
Leukemia
Model systems for rapid and slow induction of apoptosis obtained by inducible expression of pro-apoptotic proteins.
Leukemia
Modulation of anti-apoptosis by endogenous IAP expression in MKN45 human gastric cancer cells.
Leukemia
Molecular basis for the inhibition of hypoxia-induced apoptosis by 2-deoxy-D-ribose.
Leukemia
Molecular mechanism of satratoxin-induced apoptosis in HL-60 cells: activation of caspase-8 and caspase-9 is involved in activation of caspase-3.
Leukemia
Molecular response of HL-60 cells to mitotic inhibitors vincristine and taxol visualized with apoptosis-related gene expressions, including the new member BCL2L12.
Leukemia
Nanofluidic proteomic assay for serial analysis of oncoprotein activation in clinical specimens.
Leukemia
Naringenin induces apoptosis through downregulation of Akt and caspase-3 activation in human leukemia THP-1 cells.
Leukemia
Naringenin-induced apoptosis is attenuated by Bcl-2 but restored by the small molecule Bcl-2 inhibitor, HA 14-1, in human leukemia U937 cells.
Leukemia
New adamantane phenylalkylamines with ?-receptor binding affinity and anticancer activity, associated with putative antagonism of neuropathic pain.
Leukemia
Norcantharidin Inhibits SK-N-SH Neuroblastoma Cell Growth by Induction of Autophagy and Apoptosis.
Leukemia
Novel ?-substituted tropolones promote potent and selective caspase-dependent leukemia cell apoptosis.
Leukemia
Paclitaxel induces apoptosis in leukemia cells through a JNK activation-dependent pathway.
Leukemia
PECAM-1 is involved in BCR/ABL signaling and may downregulate imatinib-induced apoptosis of Philadelphia chromosome-positive leukemia cells.
Leukemia
Polychlorinated biphenyl-induced apoptosis of murine spleen cells is aryl hydrocarbon receptor independent but caspases dependent.
Leukemia
Prognostic Value of CD95, Active Caspase-3, and Bcl-2 Expression in Adult Patients with De Novo Acute Lymphoblastic Leukemia.
Leukemia
Proliferation and apoptosis in acute and chronic leukemias and myelodysplastic syndrome.
Leukemia
Propofol Treatment Inhibits Constitutive Apoptosis in Human Primary Neutrophils and Granulocyte-Differentiated Human HL60 Cells.
Leukemia
Prostaglandin D(2) and J(2) induce apoptosis in human leukemia cells via activation of the caspase 3 cascade and production of reactive oxygen species.
Leukemia
Purging effect of dibutyl phthalate on leukemia cells involves fas independent activation of caspase-3/CPP32 protease.
Leukemia
Purification of nasulysin-1: A new toxin from Porthidium nasutum snake venom that specifically induces apoptosis in leukemia cell model through caspase-3 and apoptosis-inducing factor activation.
Leukemia
Rapid engraftment of human ALL in NOD/SCID mice involves deficient apoptosis signaling.
Leukemia
Reactive oxygen species-mediated activation of JNK and down-regulation of DAXX are critically involved in penta-O-galloyl-beta-d-glucose-induced apoptosis in chronic myeloid leukemia K562 cells.
Leukemia
Regeneration and transdifferentiation potential of muscle-derived stem cells propagated as myospheres.
Leukemia
Requirement for caspase activation in monocytic differentiation of myeloid leukemia cells.
Leukemia
Resistance to apoptosis correlates with a highly proliferative phenotype and loss of Fas and CPP32 (caspase-3) expression in human leukemia cells.
Leukemia
Resveratrol enhances anticancer effects of paclitaxel in HepG2 human liver cancer cells.
Leukemia
RGD peptide-induced apoptosis in human leukemia HL-60 cells requires caspase-3 activation.
Leukemia
Rhabdastrellic acid-A inhibited PI3K/Akt pathway and induced apoptosis in human leukemia HL-60 cells.
Leukemia
Role of epigenetic regulation on the induction of apoptosis in Jurkat leukemia cells by white grape pomace rich in phenolic compounds.
Leukemia
Ru(II)-Thymine Complex Causes Cell Growth Inhibition and Induction of Caspase-Mediated Apoptosis in Human Promyelocytic Leukemia HL-60 Cells.
Leukemia
Sanguinarine-induced apoptosis in human leukemia U937 cells via Bcl-2 downregulation and caspase-3 activation.
Leukemia
Sann-Joong-Kuey-Jian-Tang decreases the protein expression of Mcl?1 and TCTP and increases that of TNF-? and Bax in BxPC?3 pancreatic carcinoma cells.
Leukemia
Se-methylselenocysteine induces apoptosis through caspase activation in HL-60 cells.
Leukemia
Selective inhibition of human leukemia cell growth and induction of cell cycle arrest and apoptosis by pseudolaric acid B.
Leukemia
Selenium modulates oxidative stress-induced cell apoptosis in human myeloid HL-60 cells through regulation of calcium release and caspase-3 and -9 activities.
Leukemia
Signaling defect in the activation of caspase-3 and PKCdelta in human TUR leukemia cells is associated with resistance to apoptosis.
Leukemia
Sorafenib inhibited cell growth through the MEK/ERK signaling pathway in acute promyelocytic leukemia cells.
Leukemia
Specific cleavage of Mcl-1 by caspase-3 in tumor necrosis factor-related apoptosis-inducing ligand (TRAIL)-induced apoptosis in Jurkat leukemia T cells.
Leukemia
Sphingosine 1-phosphate antagonizes apoptosis of human leukemia cells by inhibiting release of cytochrome c and Smac/DIABLO from mitochondria.
Leukemia
Stratification of pediatric ALL by in vitro cellular responses to DNA double-strand breaks provides insight into the molecular mechanisms underlying clinical response.
Leukemia
Subcellular localization of caspase-3 activation correlates with changes in apoptotic morphology in MOLT-4 leukemia cells exposed to X-ray irradiation.
Leukemia
Synergistic enhancement of apoptosis by DNA- and cytoskeleton-damaging agents: a basis for combination chemotherapy of cancer.
Leukemia
Synergistic property of cordycepin in cultivated Cordyceps militaris-mediated apoptosis in human leukemia cells.
Leukemia
Tanshinone IIA inhibits human gastric carcinoma AGS cell growth by decreasing BiP, TCTP, Mcl?1 and Bcl?xL and increasing Bax and CHOP protein expression.
Leukemia
Tanshinone IIA, an ingredient of Salvia miltiorrhiza BUNGE, induces apoptosis in human leukemia cell lines through the activation of caspase-3.
Leukemia
Targeting MLL-AF4 with short interfering RNAs inhibits clonogenicity and engraftment of t(4;11)-positive human leukemic cells.
Leukemia
Taxol-induced apoptosis in human SKOV3 ovarian and MCF7 breast carcinoma cells is caspase-3 and caspase-9 independent.
Leukemia
The important role of ADAM8 in the progression of hepatocellular carcinoma induced by diethylnitrosamine in mice.
Leukemia
The mechanism of tumor cell clearance by rituximab in vivo in patients with B-cell chronic lymphocytic leukemia: evidence of caspase activation and apoptosis induction.
Leukemia
The novel function of CD82 and its impact on BCL2L12 via AKT/STAT5 signal pathway in acute myelogenous leukemia cells.
Leukemia
The novel triterpenoid 2-cyano-3,12-dioxooleana-1,9-dien-28-oic acid (CDDO) potently enhances apoptosis induced by tumor necrosis factor in human leukemia cells.
Leukemia
Thrombospondin-1 induces apoptosis in primary leukemia and cell lines mediated by CD36 and Caspase-3.
Leukemia
Tumor Cell-Derived Microvesicles Induced Not Epithelial-Mesenchymal Transition but Apoptosis in Human Proximal Tubular (HK-2) Cells: Implications for Renal Impairment in Multiple Myeloma.
Leukemia
Tumor-specific cytotoxicity and type of cell death induced by benzo[b]cyclohept[e][1,4]oxazine and 2-aminotropone derivatives.
Leukemia
Tumor-specific cytotoxicity and type of cell death induced by gefitinib in oral squamous cell carcinoma cell lines.
Leukemia
Ultrasound mediated drug-loaded nanoparticles crossing cell membranes as a new strategy to reverse cancer multidrug resistance.
Leukemia
Up-regulation of Bax and endonuclease G, and down-modulation of Bcl-XL involved in cardiotoxin III-induced apoptosis in K562 cells.
Leukemia
Vinorelbine induces apoptosis and caspase-3 (CPP32) expression in leukemia and lymphoma cells: a comparison with vincristine.
Leukemia
Viscum articulatum Burm. f. aqueous extract exerts antiproliferative effect and induces cell cycle arrest and apoptosis in leukemia cells.
Leukemia
Wasabi 6-(methylsulfinyl)hexyl isothiocyanate induces apoptosis in human colorectal cancer cells through p53-independent mitochondrial dysfunction pathway.
Leukemia
WK175, a novel antitumor agent, decreases the intracellular nicotinamide adenine dinucleotide concentration and induces the apoptotic cascade in human leukemia cells.
Leukemia
Xanthoangelol, a major chalcone constituent of Angelica keiskei, induces apoptosis in neuroblastoma and leukemia cells.
Leukemia
Xanthohumol activates the proapoptotic arm of the unfolded protein response in chronic lymphocytic leukemia.
Leukemia
Xanthohumol induces paraptosis of leukemia cells through p38 mitogen activated protein kinase signaling pathway.
Leukemia
Yansuanmalingua inhibits replication of type 2 porcine reproductive and respiratory syndrome virus via activating the caspase-8 apoptosis pathway.
Leukemia
Zephycandidine A, the First Naturally Occurring Imidazo[1,2-f]phenanthridine Alkaloid from Zephyranthes candida, Exhibits Significant Anti-tumor and Anti-acetylcholinesterase Activities.
Leukemia
[Antitumor mechanism of 3-bromopropionylamino benzoylurea on leukemia and lymphoma]
Leukemia
[Down-regulation of HDAC6 Expression Promotes Apoptosis of Human Leukemia K562 Cells].
Leukemia
[Effect of Down-Regulating the CD59 by RNAi Lentivirus on the Expression of Acute T-lineage Leukemia Jurkat Cell Line].
Leukemia
[Effects of SODD and survivin on leukemia cell apoptosis induced by chemotherapeutic drugs]
Leukemia
[Ginsenoside Rh? induces apoptosis and autophagy of K562 cells by activating p38].
Leukemia
[Role of High Mobility Group Box 1 in Adriamycin-induced Apoptosis in Leukemia K562 Cells.]
Leukemia
[The mechanism for SHIP gene to induce the apoptosis of human leukemia cell line K562.]
Leukemia L1210
Induction of apoptosis associated with chromosomal DNA fragmentation and caspase-3 activation in leukemia L1210 cells by TiO2 nanoparticles.
Leukemia L1210
Inhibitors of diverse metabolic steps cause increased apoptosis in deoxyadenosine-resistant mouse leukemia L1210 cells that lack p53 expression: convergence at caspase-3 activation.
Leukemia L1210
The effect of 3-(5-nitro-2-thienyl)-9-chloro-5-morpholin-4-yl[1,2,4]triazolo[4,3-c]quinazoline on cell growth, cell cycle, induction of DNA fragmentation, and activity of caspase 3 in murine leukemia L1210 cells and fibroblast NIH-3T3 cells.
Leukemia, B-Cell
Apoptosis in meningoencephalitis of Angiostrongylus cantonensis-infected mice.
Leukemia, B-Cell
Decrease of Bcl-xL and augmentation of thymocyte apoptosis in GILZ overexpressing transgenic mice.
Leukemia, B-Cell
Dietary docosahexaenoic acid decreased lipid accumulation via inducing adipocytes apoptosis of grass carp, Ctenopharygodon idella.
Leukemia, B-Cell
Effects of Salvia miltiorrhiza on CNS Neuronal Injury and Degeneration: A Plausible Complementary Role of Tanshinones and Depsides.
Leukemia, B-Cell
EPA plays multiple roles in regulating lipid accumulation of grass carp Ctenopharyngodon idella adipose tissue in vitro and in vivo.
Leukemia, B-Cell
The important role of ADAM8 in the progression of hepatocellular carcinoma induced by diethylnitrosamine in mice.
Leukemia, Erythroblastic, Acute
A novel synthesized 3', 5'-diprenylated chalcone mediates the proliferation of human leukemia cells by regulating apoptosis and autophagy pathways.
Leukemia, Erythroblastic, Acute
Activation of the intrinsic and extrinsic pathways in high pressure-induced apoptosis of murine erythroleukemia cells.
Leukemia, Erythroblastic, Acute
Berberis libanotica extract targets NF-?B/COX-2, PI3K/Akt and mitochondrial/caspase signalling to induce human erythroleukemia cell apoptosis.
Leukemia, Erythroblastic, Acute
Late apoptotic effects of taxanes on K562 erythroleukemia cells: apoptosis is delayed upstream of caspase-3 activation.
Leukemia, Erythroblastic, Acute
[Induction of apoptosis by proteasome inhibitor MG-132 in human erythroleukemia cell line K562.]
Leukemia, Lymphocytic, Chronic, B-Cell
Flavopiridol induces apoptosis in chronic lymphocytic leukemia cells via activation of caspase-3 without evidence of bcl-2 modulation or dependence on functional p53.
Leukemia, Lymphocytic, Chronic, B-Cell
Genetic variants in caspase genes and susceptibility to non-Hodgkin lymphoma.
Leukemia, Lymphocytic, Chronic, B-Cell
Hydroxychloroquine-induced apoptosis of chronic lymphocytic leukemia involves activation of caspase-3 and modulation of Bcl-2/bax/ratio.
Leukemia, Lymphocytic, Chronic, B-Cell
Immunolocalization of the ICE/Ced-3-family protease, CPP32 (Caspase-3), in non-Hodgkin's lymphomas, chronic lymphocytic leukemias, and reactive lymph nodes.
Leukemia, Lymphocytic, Chronic, B-Cell
Induction of an apoptotic program in cell-free extracts by 2-chloro-2'-deoxyadenosine 5'-triphosphate and cytochrome c.
Leukemia, Lymphocytic, Chronic, B-Cell
Proliferation and apoptosis in acute and chronic leukemias and myelodysplastic syndrome.
Leukemia, Lymphocytic, Chronic, B-Cell
Resveratrol and quercetin-induced apoptosis of human 232B4 chronic lymphocytic leukemia cells by activation of caspase-3 and cell cycle arrest.
Leukemia, Myelogenous, Chronic, BCR-ABL Positive
Apoptotic effects of some tetrahydronaphthalene derivatives on K562 human chronic myelogenous leukemia cell line.
Leukemia, Myelogenous, Chronic, BCR-ABL Positive
Bortezomib and sphingosine kinase inhibitor interact synergistically to induces apoptosis in BCR/ABl+ cells sensitive and resistant to STI571 through down-regulation Mcl-1.
Leukemia, Myelogenous, Chronic, BCR-ABL Positive
CdSeTe@CdS@ZnS Quantum-Dot-Sensitized Macroporous Tio2 Film: A Multisignal-Amplified Photoelectrochemical Platform.
Leukemia, Myelogenous, Chronic, BCR-ABL Positive
Proliferation and apoptosis in acute and chronic leukemias and myelodysplastic syndrome.
Leukemia, Myelogenous, Chronic, BCR-ABL Positive
Puncta intended: connecting the dots between autophagy and cell stress networks.
Leukemia, Myelogenous, Chronic, BCR-ABL Positive
Reactive oxygen species-mediated activation of JNK and down-regulation of DAXX are critically involved in penta-O-galloyl-beta-d-glucose-induced apoptosis in chronic myeloid leukemia K562 cells.
Leukemia, Myelogenous, Chronic, BCR-ABL Positive
Sensitive and selective plasmon ruler nanosensors for monitoring the apoptotic drug response in leukemia.
Leukemia, Myelogenous, Chronic, BCR-ABL Positive
Toward therapeutic effects evaluation of chronic myeloid leukemia drug: electrochemical platform for caspase-3 activity sensing.
Leukemia, Myelogenous, Chronic, BCR-ABL Positive
[Effect of emodin on proliferation inhibition and apoptosis induction in leukemic k562 cells]
Leukemia, Myelogenous, Chronic, BCR-ABL Positive
[Effects of 2-methoxyestradiol on the Expression of Caspase-3 and Survivin in Chronic Myelocytic Leukemia K562 Cells.]
Leukemia, Myelogenous, Chronic, BCR-ABL Positive
[Effects of hyperbaric oxygenation combined with as(2)o(3) on proliferation of k562 cells and associated mechanism].
Leukemia, Myelogenous, Chronic, BCR-ABL Positive
[Effects of STI571 combind with As?O? on proliferation, apoptosis and caspase 3, Bcl-xL expression of K562 cells].
Leukemia, Myeloid
Antiproliferation effects of ponicidin on human myeloid leukemia cells in vitro.
Leukemia, Myeloid
Arctigenin induces necroptosis through mitochondrial dysfunction with CCN1 upregulation in prostate cancer cells under lactic acidosis.
Leukemia, Myeloid
Bcl-2 protects against beta-lapachone-mediated caspase 3 activation and apoptosis in human myeloid leukemia (HL-60) cells.
Leukemia, Myeloid
Boswellic acid acetate induces apoptosis through caspase-mediated pathways in myeloid leukemia cells.
Leukemia, Myeloid
Candidone Inhibits Migration and Invasion, and Induces Apoptosis in HepG2 Cells.
Leukemia, Myeloid
DMNQ-S17 inhibits constitutive NF-kappaB activation leading to induction of apoptosis through the activation of caspase-3 in human myeloid leukemia U937 cells.
Leukemia, Myeloid
Human Cytomegalovirus Stimulates the Synthesis of Select Akt-Dependent Antiapoptotic Proteins during Viral Entry To Promote Survival of Infected Monocytes.
Leukemia, Myeloid
Inactivation of PI3k/Akt signaling pathway and activation of caspase-3 are involved in tanshinone I-induced apoptosis in myeloid leukemia cells in vitro.
Leukemia, Myeloid
The Effect of Bornyl cis-4-Hydroxycinnamate on Melanoma Cell Apoptosis Is Associated with Mitochondrial Dysfunction and Endoplasmic Reticulum Stress.
Leukemia, Myeloid
[Apoptosis of myeloid leukemia cell line HL60 induced by Bortezomib, a proteasome inhibitor]
Leukemia, Myeloid, Acute
A Gli inhibitor GANT61 suppresses cell proliferation, promotes cell apoptosis and induces G1/G0 cycle retardation with a dose- and time-dependent manner through inhibiting Notch pathway in multiple myeloma.
Leukemia, Myeloid, Acute
An anti-apoptotic pattern correlates with multidrug resistance in acute myeloid leukemia patients: a comparative study of active caspase-3, cleaved PARPs, Bcl-2, Survivin and MDR1 gene.
Leukemia, Myeloid, Acute
Bortezomib interferes with C-KIT processing and transforms the t(8;21)-generated fusion proteins into tumor-suppressing fragments in leukemia cells.
Leukemia, Myeloid, Acute
Caspase 2 and caspase 3 as predictors of complete remission and survival in adults with acute lymphoblastic leukemia.
Leukemia, Myeloid, Acute
Caspase 2 and caspase 3 protein levels as predictors of survival in acute myelogenous leukemia.
Leukemia, Myeloid, Acute
Determination of caspase-3 activation fails to predict chemosensitivity in primary acute myeloid leukemia blasts.
Leukemia, Myeloid, Acute
Differential response of human acute myeloid leukemia cells to gemtuzumab ozogamicin in vitro: role of Chk1 and Chk2 phosphorylation and caspase 3.
Leukemia, Myeloid, Acute
Expression of apoptosis-controlling proteins in acute leukemia cells.
Leukemia, Myeloid, Acute
Hydroquinone, a bioreactive metabolite of benzene, inhibits apoptosis in myeloblasts.
Leukemia, Myeloid, Acute
Intact apoptosis signaling in myeloid leukemia cells determines treatment outcome in childhood AML.
Leukemia, Myeloid, Acute
MicroRNA-199 inhibits proliferation and promotes apoptosis in children with acute myeloid leukemia by mediating caspase-3.
Leukemia, Myeloid, Acute
Overexpression of Bcl-X(L) inhibits Ara-C-induced mitochondrial loss of cytochrome c and other perturbations that activate the molecular cascade of apoptosis.
Leukemia, Myeloid, Acute
Proliferation and apoptosis in acute and chronic leukemias and myelodysplastic syndrome.
Leukemia, Myeloid, Acute
Spontaneous down-regulation of Fas-associated phosphatase-1 may contribute to excessive apoptosis in myelodysplastic marrows.
Leukemia, Myeloid, Acute
Structure-based discovery of an organic compound that binds Bcl-2 protein and induces apoptosis of tumor cells.
Leukemia, Myeloid, Acute
The antidepressants imipramine, clomipramine, and citalopram induce apoptosis in human acute myeloid leukemia HL-60 cells via caspase-3 activation.
Leukemia, Myeloid, Acute
The clinical significance of caspase regulation in acute leukemia.
Leukemia, Myeloid, Acute
The vascular targeting agent combretastatin-A4 and a novel cis-Restricted {beta}-Lactam Analogue, CA-432, induce apoptosis in human chronic myeloid leukemia cells and ex vivo patient samples including those displaying multidrug resistance.
Leukemia, Myelomonocytic, Chronic
Proliferation and apoptosis in acute and chronic leukemias and myelodysplastic syndrome.
Leukemia, Promyelocytic, Acute
A new pyridazinone exhibits potent cytotoxicity on human cancer cells via apoptosis and poly-ubiquitinated protein accumulation.
Leukemia, Promyelocytic, Acute
Arsenic trioxide-induced apoptosis and differentiation are associated respectively with mitochondrial transmembrane potential collapse and retinoic acid signaling pathways in acute promyelocytic leukemia.
Leukemia, Promyelocytic, Acute
cAMP protects acute promyelocytic leukemia cells from arsenic trioxide-induced caspase-3 activation and apoptosis.
Leukemia, Promyelocytic, Acute
Curcumin-induced cell cycle arrest and apoptosis in human acute promyelocytic leukemia HL-60 cells via MMP changes and caspase-3 activation.
Leukemia, Promyelocytic, Acute
Induction of caspase 3 activity, bcl-2 bax and p65 gene expression modulation in human acute promyelocytic leukemia HL-60 cells by doxorubicin with amifostine.
Leukemia, Promyelocytic, Acute
Induction of caspase 3 and modulation of some apoptotic genes in human acute promyelocytic leukemia HL-60 cells by carboplatin with amifostine.
Leukemia, Promyelocytic, Acute
Lentiviral vector-mediated RNA interference targeted against prohibitin inhibits apoptosis of the retinoic acid-resistant acute promyelocytic leukemia cell line NB4-R1.
Leukemia, T-Cell
Caspase-mediated cleavage of DNA topoisomerase I at unconventional sites during apoptosis.
Leukemia, T-Cell
Dietary ginger constituents, galanals A and B, are potent apoptosis inducers in Human T lymphoma Jurkat cells.
Leukemia, T-Cell
Doxorubicin-induced apoptosis in human T-cell leukemia is mediated by caspase-3 activation in a Fas-independent way.
Leukemia, T-Cell
Human T cell leukemia cell death by apoptosis-inducing nucleosides from CD57(+) HLA-DR(bright) natural suppressor cell line.
Leukemia, T-Cell
Paraoxon induces apoptosis in EL4 cells via activation of mitochondrial pathways.
Leukemia, T-Cell
Screening for inducers of apoptosis in apoptosis-resistant human carcinoma cells.
Leukemia-Lymphoma, Adult T-Cell
Selective accumulation of hybrid liposomes into adult T-cell leukemia cells along with induction of apoptosis.
Leukemic Infiltration
Fli-1 overexpression in erythroleukemic cells promotes erythroid de-differentiation while Spi-1/PU.1 exerts the opposite effect.
Leukocytosis
Comparative Toxicological Effects of Biologically and Chemically Synthesized Copper Oxide Nanoparticles on Mice.
Leukopenia
A novel SLC37A4 missense mutation in GSD-Ib without hepatomegaly causes enhanced leukocytes endoplasmic reticulum stress and apoptosis.
Leukopenia
Hemorrhage Exacerbates Radiation Effects on Survival, Leukocytopenia, Thrombopenia, Erythropenia, Bone Marrow Cell Depletion and Hematopoiesis, and Inflammation-Associated microRNAs Expression in Kidney.
Leukopenia
Overexpression of MCM2 in myelodysplastic syndromes: Association with bone marrow cell apoptosis and peripheral cytopenia.
Leukoplakia, Oral
[Expression of survivin, caspase-3 in oral precancerous lesions and oral squamous-cell carcinoma.]
Leukostasis
Inactivation of Endothelial ADAM17 Reduces Retinal Ischemia-Reperfusion Induced Neuronal and Vascular Damage.
Lichen Planus
Expression of apoptosis related protein in skin lesions of lichen planus and its implication.
Lichen Planus
Increased caspase-3 and altered expression of apoptosis-associated proteins, Bcl-2 and Bax in lichen planus.
Lichen Planus, Oral
Cell cycle regulating mechanisms in oral lichen planus: molecular bases in epithelium predisposed to malignant transformation.
Lichen Planus, Oral
Expression of caspase-3 and structural changes associated with apoptotic cell death of keratinocytes in oral lichen planus.
Lichen Planus, Oral
No differences in caspase-3 and Bax expression in atrophic-erosive vs. reticular oral lichen planus.
Lip Neoplasms
Immunoexpression of cleaved caspase-3 shows lower apoptotic area indices in lip carcinomas than in intraoral cancer.
Lipodystrophy
Immunohistochemical analysis of the expression of TNF-alpha, TGF-beta, and caspase-3 in subcutaneous tissue of patients with HIV Lipodystrophy Syndrome.
Liposarcoma
The histone deacetylase inhibitor vorinostat selectively sensitizes fibrosarcoma cells to chemotherapy.
Liposarcoma, Myxoid
Kinome profiling of myxoid liposarcoma reveals NF-kappaB-pathway kinase activity and casein kinase II inhibition as a potential treatment option.
Listeriosis
Protein kinase C-theta critically regulates the proliferation and survival of pathogen-specific T cells in murine listeriosis.
Liver Cirrhosis
Abscisic acid ameliorates oxidative stress, inflammation, and apoptosis in thioacetamide-induced hepatic fibrosis by regulating the NF-?B signaling pathway in mice.
Liver Cirrhosis
Active Compounds Derived from Fuzheng Huayu Formula Protect Hepatic Parenchymal Cells from Apoptosis Based on Network Pharmacology and Transcriptomic Analysis.
Liver Cirrhosis
Antifibrotic activity of hesperidin against dimethylnitrosamine-induced liver fibrosis in rats.
Liver Cirrhosis
Attenuation of early liver fibrosis by pharmacological inhibition of smoothened receptor signaling.
Liver Cirrhosis
Baicalin Ameliorates Experimental Liver Cholestasis in Mice by Modulation of Oxidative Stress, Inflammation, and NRF2 Transcription Factor.
Liver Cirrhosis
Clinical Implications of HBV PreS/S Mutations and the Effects of PreS2 Deletion on Mitochondria, Liver Fibrosis, and Cancer Development.
Liver Cirrhosis
Down-regulation of LncRNA UCA1 alleviates liver injury in rats with liver cirrhosis.
Liver Cirrhosis
Expression of tumour necrosis factor-related apoptosis-inducing ligand and caspase-3 in relation to grade of inflammation and stage of fibrosis in chronic hepatitis C.
Liver Cirrhosis
Ginkgo biloba extract mitigates liver fibrosis and apoptosis by regulating p38 MAPK, NF-?B/I?B?, and Bcl-2/Bax signaling.
Liver Cirrhosis
Liver Bid suppression for treatment of fibrosis associated with non-alcoholic steatohepatitis.
Liver Cirrhosis
P7C3-A20, a neuroprotective agent, alleviates fatty liver by inducing FGF21/FGF1 in a LKB1/AMPK/CRTC2-dependent manner and shaping gut microbiota.
Liver Cirrhosis
Salvianolic acid A attenuates CCl4-induced liver fibrosis by regulating the PI3K/AKT/mTOR, Bcl-2/Bax and caspase-3/cleaved caspase-3 signaling pathways.
Liver Cirrhosis
Systems Pharmacology Study of the Anti-Liver Injury Mechanism of Citri Reticulatae Pericarpium.
Liver Cirrhosis
Tissue inhibitor of metalloproteinases-1 attenuates spontaneous liver fibrosis resolution in the transgenic mouse.
Liver Cirrhosis, Biliary
Inactivation of caspase 8 in liver parenchymal cells confers protection against murine obstructive cholestasis.
Liver Diseases
Autophagy in ovary and polycystic ovary syndrome: role, dispute and future perspective.
Liver Diseases
Expression of TLR-2 in hepatocellular carcinoma is associated with tumour proliferation, angiogenesis and Caspase-3 expression.
Liver Diseases
Foxp3 expression in liver correlates with the degree but not the cause of inflammation.
Liver Diseases
High serum caspase-3 levels in hepatocellular carcinoma prior to liver transplantation and high mortality risk during the first year after liver transplantation.
Liver Diseases
Levels of Hepatic Activating Transcription Factor 6 and Caspase-3 Are Downregulated in Mice after Excessive Training.
Liver Diseases
Prevention of hypoxic liver cell necrosis by in vivo human bcl-2 gene transfection.
Liver Failure
Anti-apoptotic function of gelsolin in fas antibody-induced liver failure in vivo.
Liver Failure
Gasdermin E-derived caspase-3 inhibitors effectively protect mice from acute hepatic failure.
Liver Failure
[Preliminary study of antimicrobial peptide cathelicidin-PY therapy in mice with acute liver failure].
Liver Failure
[Tumor necrosis factor-alpha, caspase-3 expression and hepatocyte apoptosis in fulminanting hepatic failure]
Liver Failure, Acute
Characterization of pro-apoptotic effect of liver failure plasma on primary human hepatocytes and its modulation by molecular adsorbent recirculation system therapy.
Liver Failure, Acute
Contribution of hepatic stellate cells and matrix metalloproteinase 9 in acute liver failure.
Liver Failure, Acute
Gasdermin E-derived caspase-3 inhibitors effectively protect mice from acute hepatic failure.
Liver Failure, Acute
The protective effects of total saponins from Ornithogalum saundersiae (Liliaceae) on acute hepatic failure induced by lipopolysaccharide and d-galactosamine in mice.
Liver Failure, Acute
[Effect of Sanhuangyinchi decoction on liver damage and caspase-3 in rats with acute hepatic failure].
Liver Failure, Acute
[Sanhuangyinchi decoction pretreatment ameliorates acute hepatic failure in rats by suppressing antioxidant stress and caspase-3 expression].
Liver Failure, Acute
[Tumor necrosis factor-alpha, caspase-3 expression and hepatocyte apoptosis in fulminanting hepatic failure]
Liver Neoplasms
A ligand for peroxisome proliferator activated receptor gamma inhibits cell growth and induces apoptosis in human liver cancer cells.
Liver Neoplasms
A novel small molecule inhibits STAT3 phosphorylation and DNA binding activity and exhibits potent growth suppressive activity in human cancer cells.
Liver Neoplasms
Anticancer Activity of Novel Plant Extracts and Compounds from Adenosma bracteosum (Bonati) in Human Lung and Liver Cancer Cells.
Liver Neoplasms
Anticancer effect of xanthohumol induces growth inhibition and apoptosis of human liver cancer through NF-?B/p53-apoptosis signaling pathway.
Liver Neoplasms
Baohuoside-1 targeting mTOR inducing apoptsis to inhibit hepatocellular carcinoma proliferation, invasion and migration.
Liver Neoplasms
Caspase-3 gene transfected with LIGHT gene: can it be used for therapy of human hepatocellular carcinoma?
Liver Neoplasms
Cinchonine activates endoplasmic reticulum stress-induced apoptosis in human liver cancer cells.
Liver Neoplasms
Comparison of the Phytochemical Properties, Antioxidant Activity and Cytotoxic Effect on HepG2 Cells in Mongolian and Taiwanese Rhubarb Species.
Liver Neoplasms
Critical role of tristetraprolin and AU-rich element RNA-binding protein 1 in the suppression of cancer cell growth by globular adiponectin.
Liver Neoplasms
Crude extracts of Euchresta formosana radix inhibit invasion and migration of human hepatocellular carcinoma cells.
Liver Neoplasms
Cytotoxicity of Moringa oleifera fruits on human liver cancer and molecular docking analysis of bioactive constituents against caspase-3 enzyme.
Liver Neoplasms
Demethylation of miR-34a upregulates expression of membrane palmitoylated proteins and promotes the apoptosis of liver cancer cells.
Liver Neoplasms
Dendrobium candidum extract inhibits proliferation and induces apoptosis of liver cancer cells by inactivating Wnt/?-catenin signaling pathway.
Liver Neoplasms
Detailed studies on the anticancer action of rosmarinic acid in human Hep-G2 liver carcinoma cells: evaluating its effects on cellular apoptosis, caspase activation and suppression of cell migration and invasion.
Liver Neoplasms
Downregulation of thioredoxin-1-dependent CD95 S-nitrosation by Sorafenib reduces liver cancer.
Liver Neoplasms
Effect of targeted magnetic nanoparticles containing 5-FU on expression of bcl-2, bax and caspase 3 in nude mice with transplanted human liver cancer.
Liver Neoplasms
Effects of MicroRNA-132 Transfection on the Proliferation and Apoptosis of Human Liver Cancer Cells in vitro and in vivo.
Liver Neoplasms
Effects of tocotrienols on cell viability and apoptosis in normal murine liver cells (BNL CL.2) and liver cancer cells (BNL 1ME A.7R.1), in vitro.
Liver Neoplasms
Erratum: Photothermal treatment of liver cancer with albumin-conjugated gold nanoparticles initiates Golgi Apparatus-ER dysfunction and caspase-3 apoptotic pathway activation by selective targeting of Gp60 receptor [Corrigendum].
Liver Neoplasms
Glaucocalyxin A inhibits the growth of liver cancer Focus and SMMC-7721 cells.
Liver Neoplasms
Goniothalamin selectively induces apoptosis on human hepatoblastoma cells through caspase-3 activation.
Liver Neoplasms
Hepatic somatostatin receptor 2 expression during premalignant stages of hepatocellular carcinoma.
Liver Neoplasms
Involvement of the prostaglandin E receptor EP2 in paeoniflorin-induced human hepatoma cell apoptosis.
Liver Neoplasms
Knockdown of ACTA2?AS1 promotes liver cancer cell proliferation, migration and invasion.
Liver Neoplasms
Lactonic sophorolipid-induced apoptosis in human HepG2 cells through the Caspase-3 pathway.
Liver Neoplasms
Mefenamic acid-induced apoptosis in human liver cancer cell-lines through caspase-3 pathway.
Liver Neoplasms
MicroRNA-34a suppresses aggressiveness of hepatocellular carcinoma by modulating E2F1, E2F3, and Caspase-3.
Liver Neoplasms
MicroRNA-490-3p suppresses the proliferation and invasion of hepatocellular carcinoma cells via targeting TMOD3.
Liver Neoplasms
Novel Benzyloxyphenyl Pyrimidine-5-Carbonitrile Derivatives as Potential Apoptotic Antiproliferative Agents.
Liver Neoplasms
Novel Death Defying Domain in met entraps the active site of caspase-3 and blocks apoptosis in hepatocytes.
Liver Neoplasms
Photothermal treatment of liver cancer with albumin-conjugated gold nanoparticles initiates Golgi Apparatus-ER dysfunction and caspase-3 apoptotic pathway activation by selective targeting of Gp60 receptor.
Liver Neoplasms
Preparation of morusin from Ramulus mori and its effects on mice with transplanted H22 hepatocarcinoma.
Liver Neoplasms
Quercetin nanoparticles display antitumor activity via proliferation inhibition and apoptosis induction in liver cancer cells.
Liver Neoplasms
Reactive oxygen species-mediated activation of JNK and down-regulation of DAXX are critically involved in penta-O-galloyl-beta-d-glucose-induced apoptosis in chronic myeloid leukemia K562 cells.
Liver Neoplasms
Regorafenib and ginsenoside combination therapy: inhibition of HepG2 cell growth through modulating survivin and caspase-3 gene expression.
Liver Neoplasms
Regulatory Mechanisms of Coicis Semen on Bionetwork of Liver Cancer Based on Network Pharmacology.
Liver Neoplasms
Repressing of NHERF1 inhibits liver cancer progression by promoting the production of ROS.
Liver Neoplasms
The bioactive ingredients in Actinidia chinensis Planch. Inhibit liver cancer by inducing apoptosis.
Liver Neoplasms
The effect of JAK2 knockout on inhibition of liver tumor growth by inducing apoptosis, autophagy and anti-proliferation via STATs and PI3K/AKT signaling pathways.
Liver Neoplasms
The Pro-Apoptotic Activity of Tamarixetin on Liver Cancer Cells Via Regulation Mitochondrial Apoptotic Pathway.
Liver Neoplasms
TRAIL-secreting mesenchymal stem cells promote apoptosis in heat-shock-treated liver cancer cells and inhibit tumor growth in nude mice.
Liver Neoplasms
Upregulation of Akt/NF-?B-regulated inflammation and Akt/Bad-related apoptosis signaling pathway involved in hepatic carcinoma process: suppression by carnosic acid nanoparticle.
Lung Diseases
Fas and fas ligand are up-regulated in pulmonary edema fluid and lung tissue of patients with acute lung injury and the acute respiratory distress syndrome.
Lung Diseases
Sulfur dioxide attenuates LPS-induced acute lung injury via enhancing polymorphonuclear neutrophil apoptosis.
Lung Diseases, Interstitial
High molecular weight vimentin complex is formed after proteolytic digestion of vimentin by caspase-3: detection by sera of patients with interstitial pneumonia.
Lung Injury
Activation of Type II Cells Into Regenerative Sca-1(+) Cells During Alveolar Repair.
Lung Injury
An amyloidogenic hexapeptide derived from amylin attenuates inflammation and acute lung injury in murine sepsis.
Lung Injury
Carbon monoxide inhibition of apoptosis during ischemia-reperfusion lung injury is dependent on the p38 mitogen-activated protein kinase pathway and involves caspase 3.
Lung Injury
Cardiopulmonary, Histologic, and Inflammatory Effects of Intravenous Na2S After Blunt Chest Trauma-Induced Lung Contusion in Mice.
Lung Injury
Caspase 3 expression and plasma level of Fas ligand as apoptosis biomarkers in inflammatory endotoxemic lung injury.
Lung Injury
Caspase inhibitor zVAD-fmk protects against acute pancreatitis-associated lung injury via inhibiting inflammation and apoptosis.
Lung Injury
Caspase-3 inhibition prevents the development of hepatopulmonary syndrome in common bile duct ligation rats by alleviating pulmonary injury.
Lung Injury
Chrysotile asbestos causes AEC apoptosis via the caspase activation in vitro and in vivo.
Lung Injury
Deficiency in cold-inducible RNA-binding protein attenuates acute respiratory distress syndrome induced by intestinal ischemia-reperfusion.
Lung Injury
Depletion of resident alveolar macrophages does not prevent Fas-mediated lung injury in mice.
Lung Injury
Dexmedetomidine Ameliorates Lung Injury Induced by Intestinal Ischemia/Reperfusion by Upregulating Cannabinoid Receptor 2, Followed by the Activation of the Phosphatidylinositol 3-Kinase/Akt Pathway.
Lung Injury
Diabetes increases pancreatitis induced systemic inflammation but has little effect on inflammation and cell death in the lung.
Lung Injury
Early signs of lung fibrosis after in vitro treatment of rat lung slices with CdCl2 and TGF-beta1.
Lung Injury
Early subcutaneous administration of etanercept (Enbrel) prevents from hyperoxia-induced lung injury.
Lung Injury
Ethanol metabolism, oxidative stress, and endoplasmic reticulum stress responses in the lungs of hepatic alcohol dehydrogenase deficient deer mice after chronic ethanol feeding.
Lung Injury
Fas-mediated acute lung injury requires fas expression on nonmyeloid cells of the lung.
Lung Injury
Febuxostat, an inhibitor of xanthine oxidase, ameliorates ionizing radiation-induced lung injury by suppressing caspase-3, oxidative stress and NF-?B.
Lung Injury
In vivo knockdown of intersectin-1s alters endothelial cell phenotype and causes microvascular remodeling in the mouse lungs.
Lung Injury
Induced pluripotent stem cells alleviate lung injury from mesenteric ischemia-reperfusion.
Lung Injury
Inhibition of Alveolar Macrophage Pyroptosis Reduces Lipopolysaccharide-induced Acute Lung Injury in Mice.
Lung Injury
Intravenous dexamethasone attenuated inflammation and influenced apoptosis of lung cells in an experimental model of acute lung injury.
Lung Injury
Key developmental regulators change during hyperoxia-induced injury and recovery in adult mouse lung.
Lung Injury
Lipoxin A4 ameliorates lipopolysaccharide-induced lung injury through stimulating epithelial proliferation, reducing epithelial cell apoptosis and inhibits epithelial-mesenchymal transition.
Lung Injury
Losartan attenuated lipopolysaccharide-induced lung injury by suppression of lectin-like oxidized low-density lipoprotein receptor-1.
Lung Injury
Lung endothelial HO-1 targeting in vivo using lentiviral miRNA regulates apoptosis and autophagy during oxidant injury.
Lung Injury
Lung epithelial cell-derived extracellular vesicles activate macrophage-mediated inflammatory responses via ROCK1 pathway.
Lung Injury
Lung inflation with hydrogen during the cold ischemia phase decreases lung graft injury in rats.
Lung Injury
Melatonin attenuates lung ischaemia-reperfusion injury via inhibition of oxidative stress and inflammation.
Lung Injury
Overexpression of Sonic Hedgehog in the Lung Mimics the Effect of Lung Injury and Compensatory Lung Growth on Pulmonary Sca-1 and CD34 Positive Cells.
Lung Injury
Penehyclidine hydrochloride exerts protective effects in rats with acute lung injury via the Fas/FasL signaling pathway.
Lung Injury
Pilot Trial of Extended Hypothermic Lung Preservation to Analyze Ischemia-reperfusion Injury in Pigs.
Lung Injury
Protective Effect of Hesperidin Against Sepsis-Induced Lung Injury by Inducing the Heat-Stable Protein 70 (Hsp70)/Toll-Like Receptor 4 (TLR4)/ Myeloid Differentiation Primary Response 88 (MyD88) Pathway.
Lung Injury
Protective effect of melatonin entrapped PLGA nanoparticles on radiation-induced lung injury through the miR-21/TGF-?1/Smad3 pathway.
Lung Injury
Protein Kinase C{alpha} and {zeta} Differentially Regulate Death-Inducing Signaling Complex Formation in Cigarette Smoke Extract-Induced Apoptosis.
Lung Injury
Restoring microRNA-499-5p Protects Sepsis-Induced Lung Injury Mice Via Targeting Sox6.
Lung Injury
Shikonin ameliorates lipoteichoic acid?induced acute lung injury via promotion of neutrophil apoptosis.
Lung Injury
Silencing of fas, fas-associated via death domain, or caspase 3 differentially affects lung inflammation, apoptosis, and development of trauma-induced septic acute lung injury.
Lung Injury
Suppression of the p66shc adapter protein by protocatechuic acid prevents the development of lung injury induced by intestinal ischemia reperfusion in mice.
Lung Injury
The anesthetic agent sevoflurane attenuates pulmonary acute lung injury by modulating apoptotic pathways.
Lung Injury
The effect of miR-21-5p on the MAP2K3 expressions and cellular apoptosis in the lung tissues of neonatal rats with hyperoxia-induced lung injuries.
Lung Injury
The protective effect of N-acetylcysteine on apoptotic lung injury in cecal ligation and puncture-induced sepsis model.
Lung Injury
Therapeutical Effects and Mechanism of Salubrinal Combined with Ulinastatin on Treating Paraquat Poisoning.
Lung Injury
Time-dependent changes of autophagy and apoptosis in lipopolysaccharide-induced rat acute lung injury.
Lung Injury
[Effect of different tidal volume ventilation on rat bronchial and alveolar epithelial cell apoptosis]
Lung Injury
[Protective effects of dexmedetomidine against pulmonary ischemia-reperfusion injury during cardiopulmonary bypass in rats].
Lung Injury
[Temporal expression and significance of caspase-3 and interleukin-8 in the lungs of preterm rats exposed to hyperoxia]
Lung Injury
[The effects of Xuebijing injection on apoptosis and expression of regulatory factors TNF-??NF-?B and Caspase-3 expression in the lung tissues of acute paraquat-induced rats].
Lung Neoplasms
?-Elemene promotes cisplatin-induced cell death in human bladder cancer and other carcinomas.
Lung Neoplasms
?-elemene reverses the drug resistance of lung cancer A549/DDP cells via the mitochondrial apoptosis pathway.
Lung Neoplasms
?-Ionone derived apoptosis inducing endoperoxides; Discovery of potent leads for anticancer agents.
Lung Neoplasms
Activation of caspase-3 and cleavage of Rb are associated with p16-mediated apoptosis in human non-small cell lung cancer cells.
Lung Neoplasms
Adenoviral Bid overexpression induces caspase-dependent cleavage of truncated Bid and p53-independent apoptosis in human non-small cell lung cancers.
Lung Neoplasms
Aerosolized 3-bromopyruvate inhibits lung tumorigenesis without causing liver toxicity.
Lung Neoplasms
Altered expression profile of apoptosis-related molecules correlated with clinicopathological factors in non-small-cell lung cancer.
Lung Neoplasms
Anti-Cancer and Anti-Inflammatory Activities of Three New Chromone Derivatives from the Marine-Derived Penicillium citrinum.
Lung Neoplasms
Anti-cancer effect of snake venom toxin through down regulation of AP-1 mediated PRDX6 expression.
Lung Neoplasms
Anti-Cancer Effect of Thiacremonone through Down Regulation of Peroxiredoxin 6.
Lung Neoplasms
Antiapoptotic effects of caspase inhibitors on H2O2-treated lung cancer cells concerning oxidative stress and GSH.
Lung Neoplasms
Antitumor activity of 4-O-(2?-O-acetyl-6?-O-p-coumaroyl-?-D-glucopyranosyl)-p-coumaric acid against lung cancers via mitochondrial-mediated apoptosis.
Lung Neoplasms
Antitumor Effect of By-1 from Spent Broth from Submerged Cultures of Stout Camphor Medicinal Mushroom, Taiwanofungus camphoratus (Higher Basidiomycetes), on A549 Adenocarcinoma Cells.
Lung Neoplasms
Apoptin-modified human mesenchymal stem cells inhibit growth of lung carcinoma in nude mice.
Lung Neoplasms
Association of cooking oil fumes exposure with lung cancer: involvement of inhibitor of apoptosis proteins in cell survival and proliferation in vitro.
Lung Neoplasms
Autophagy upregulation by inhibitors of caspase-3 and mTOR enhances radiotherapy in a mouse model of lung cancer.
Lung Neoplasms
Balance between senescence and apoptosis is regulated by telomere damage-induced association between p16 and caspase-3.
Lung Neoplasms
Beauvericin-induced cell apoptosis through the mitogen-activated protein kinase pathway in human nonsmall cell lung cancer A549 cells.
Lung Neoplasms
Beetroot red (betanin) inhibits vinyl carbamate- and benzo(a)pyrene-induced lung tumorigenesis through apoptosis.
Lung Neoplasms
Bioactivity-based analysis and chemical characterization of cytotoxic constituents from Chaga mushroom (Inonotus obliquus) that induce apoptosis in human lung adenocarcinoma cells.
Lung Neoplasms
Biomimetic nanoparticle loading obatoclax mesylate for the treatment of non-small-cell lung cancer (NSCLC) through suppressing Bcl-2 signaling.
Lung Neoplasms
Black tea polyphenols restrict benzopyrene-induced mouse lung cancer progression through inhibition of Cox-2 and induction of caspase-3 expression.
Lung Neoplasms
Carbamate derivatives of betulinic acid and betulin with selective cytotoxic activity.
Lung Neoplasms
Carnosic acid and fisetin combination therapy enhances inhibition of lung cancer through apoptosis induction.
Lung Neoplasms
Caspase cleavage of Mcl-1 impairs its anti-apoptotic activity and proteasomal degradation in non-small lung cancer cells.
Lung Neoplasms
Caspase-3 knockout attenuates radiation-induced tumor repopulation via impairing the ATM/p53/Cox-2/PGE2 pathway in non-small cell lung cancer.
Lung Neoplasms
Caspase-mediated cleavage of DNA topoisomerase I at unconventional sites during apoptosis.
Lung Neoplasms
Cepharanthine induces apoptosis through reactive oxygen species and mitochondrial dysfunction in human non-small-cell lung cancer cells.
Lung Neoplasms
Chamaejasmine induces apoptosis in human non-small-cell lung cancer A549 cells through increasing the Bax/Bcl-2 ratio, caspase-3 and activating the Fas/FasL.
Lung Neoplasms
Characterization of a sulfated galactoglucan from Antrodia cinnamomea and its anticancer mechanism via TGF?/FAK/Slug axis suppression.
Lung Neoplasms
Citrus lemon essential oil nanoemulsion (CLEO-NE), a safe cell-depended apoptosis inducer in human A549 lung cancer cells with anti-angiogenic activity.
Lung Neoplasms
Clinical significance of caspase-3 expression in pathologic-stage I, nonsmall-cell lung cancer.
Lung Neoplasms
Clinicopathological significance of cathepsin D expression in non-small cell lung cancer is conditional on apoptosis-associated protein phenotype: an immunohistochemistry study.
Lung Neoplasms
COL11A1 Was Involved in Cell Proliferation, Apoptosis and Migration in Non-Small Cell Lung Cancer Cells.
Lung Neoplasms
Combretastatin CA-4 and combretastatin derivative induce mitotic catastrophe dependent on spindle checkpoint and caspase-3 activation in non-small cell lung cancer cells.
Lung Neoplasms
Condurango glycoside-rich components stimulate DNA damage-induced cell cycle arrest and ROS-mediated caspase-3 dependent apoptosis through inhibition of cell-proliferation in lung cancer, in vitro and in vivo.
Lung Neoplasms
Curcumin reverses cis-platin resistance and promotes human lung adenocarcinoma A549/DDP cell apoptosis through HIF-1? and caspase-3 mechanisms.
Lung Neoplasms
Cytotoxic effects of Pseudocerastes persicus venom and its HPLC fractions on lung cancer cells.
Lung Neoplasms
Diallyl disulfide causes caspase-dependent apoptosis in human cancer cells through a Bax-triggered mitochondrial pathway.
Lung Neoplasms
DNA damage and endoplasmic reticulum stress mediated curcumin-induced cell cycle arrest and apoptosis in human lung carcinoma A-549 cells through the activation caspases cascade- and mitochondrial-dependent pathway.
Lung Neoplasms
Down-modulation of Bcl-XL, release of cytochrome c and sequential activation of caspases during honokiol-induced apoptosis in human squamous lung cancer CH27 cells.
Lung Neoplasms
Down-regulated REIC expression in lung carcinogenesis: a molecular target for gene therapy.
Lung Neoplasms
Effects of Selenium Nanoparticles Combined With Radiotherapy on Lung Cancer Cells.
Lung Neoplasms
Effects of Spica prunellae on caspase-3-associated proliferation and apoptosis in human lung cancer cells in vitro.
Lung Neoplasms
Enhanced induction of apoptosis by combined treatment of human carcinoma cells with X rays and death receptor agonists.
Lung Neoplasms
ENTPD5 induces apoptosis in lung cancer cells via regulating caspase 3 expression.
Lung Neoplasms
Expression and the potential functions of TRIM32 in lung cancer tumorigenesis.
Lung Neoplasms
Expression of nuclear factor-kappaB and its clinical significance in nonsmall-cell lung cancer.
Lung Neoplasms
Extract of Calvatia gigantea inhibits proliferation of A549 human lung cancer cells.
Lung Neoplasms
Extraction, Characterization, Antitumor and Immunological Activities of Hemicellulose Polysaccharide from Astragalus radix Herb Residue.
Lung Neoplasms
F10, a novel hydatidiform mole-associated gene, inhibits the paclitaxel sensitivity of A549 lung cancer cells by downregulating BAX and caspase-3.
Lung Neoplasms
Folic acid (FA)-conjugated mesoporous silica nanoparticles combined with MRP-1 siRNA improves the suppressive effects of myricetin on non-small cell lung cancer (NSCLC).
Lung Neoplasms
Fucoidan upregulates TLR4/CHOP-mediated caspase-3 and PARP activation to enhance cisplatin-induced cytotoxicity in human lung cancer cells.
Lung Neoplasms
Gallic acid induces apoptosis via caspase-3 and mitochondrion-dependent pathways in vitro and suppresses lung xenograft tumor growth in vivo.
Lung Neoplasms
Gemcitabine sensitizes lung cancer cells to Fas/FasL system-mediated killing.
Lung Neoplasms
Genetic Polymorphisms in the Apoptosis-Associated Gene CASP3 and the Risk of Lung Cancer in Chinese Population.
Lung Neoplasms
Gypenosides induces apoptosis in human non-small-cell lung cancer A549 cells via increasing the Bax/Bcl-2 ratio, caspase-3 and suppressing the NF-?B.
Lung Neoplasms
Identification of polymorphisms in the Caspase-3 gene and their association with lung cancer risk.
Lung Neoplasms
Impact Analysis of miR-1253 on Lung Cancer Progression Through Targeted Regulation of ANXA3.
Lung Neoplasms
In vitro mechanisms of lovastatin on lung cancer cell lines as a potential chemopreventive agent.
Lung Neoplasms
Induction of apoptosis by combined treatment with differentiation-inducing agents and interferon-alpha in human lung cancer cells.
Lung Neoplasms
Induction of apoptosis by intracellular potassium ion depletion: using the fluorescent dye PBFI in a 96-well plate method in cultured lung cancer cells.
Lung Neoplasms
Inhibition of autophagy by autophagic inhibitors enhances apoptosis induced by bortezomib in non-small cell lung cancer cells.
Lung Neoplasms
Inhibition of fibroblast growth factor 2-induced apoptosis involves survivin expression, protein kinase C alpha activation and subcellular translocation of Smac in human small cell lung cancer cells.
Lung Neoplasms
Inhibition of lung cancer cell growth by quercetin glucuronides via G2/M arrest and induction of apoptosis.
Lung Neoplasms
Inhibition of nuclear factor kappaB chemosensitizes non-small cell lung cancer through cytochrome c release and caspase activation.
Lung Neoplasms
Inhibitory effects of hyperoside on lung cancer by inducing apoptosis and suppressing inflammatory response via caspase-3 and NF-?B signaling pathway.
Lung Neoplasms
Intrinsic capabilities of Leptospermum javanicum in inducing apoptosis and suppressing the metastatic potential of human lung carcinoma cells.
Lung Neoplasms
Inverse correlation between apoptotic (Fas ligand, caspase-3) and angiogenic factors (VEGF, microvessel density) in squamous cell lung carcinomas.
Lung Neoplasms
Involvement of Bcl-2 family, cytochrome c and caspase 3 in induction of apoptosis by beauvericin in human non-small cell lung cancer cells.
Lung Neoplasms
Involvement of CASP3 promoter polymorphism (-1337 C?>?G) in the development and progression of non-small cell lung cancer.
Lung Neoplasms
Kinesin light chain-4 depletion induces apoptosis of radioresistant cancer cells by mitochondrial dysfunction via calcium ion influx.
Lung Neoplasms
Knockdown of GluA2 induces apoptosis in non-small-cell lung cancer A549 cells through the p53 signaling pathway.
Lung Neoplasms
M867, a novel selective inhibitor of caspase-3 enhances cell death and extends tumor growth delay in irradiated lung cancer models.
Lung Neoplasms
Measurement of conatumumab-induced apoptotic activity in tumors by fine needle aspirate sampling.
Lung Neoplasms
Melanoma antigen A4 is expressed in non-small cell lung cancers and promotes apoptosis.
Lung Neoplasms
MicroRNA-145 replacement effect on growth and migration inhibition in lung cancer cell line.
Lung Neoplasms
MicroRNA-224 is implicated in lung cancer pathogenesis through targeting caspase-3 and caspase-7.
Lung Neoplasms
MiR-16 targets Bcl-2 in paclitaxel-resistant lung cancer cells and overexpression of miR-16 along with miR-17 causes unprecedented sensitivity by simultaneously modulating autophagy and apoptosis.
Lung Neoplasms
MiR-205 and miR-218 expression is associated with carboplatin chemoresistance and regulation of apoptosis via Mcl-1 and Survivin in lung cancer cells.
Lung Neoplasms
MiR-222-3p Promotes Cell Proliferation and Inhibits Apoptosis by Targeting PUMA (BBC3) in Non-Small Cell Lung Cancer.
Lung Neoplasms
Mitogen-activated protein kinase phosphatase-1 modulated JNK activation is critical for apoptosis induced by inhibitor of epidermal growth factor receptor-tyrosine kinase.
Lung Neoplasms
Molecular mechanism of Antrodia cinnamomea sulfated polysaccharide on the suppression of lung cancer cell growth and migration via induction of transforming growth factor ? receptor degradation.
Lung Neoplasms
Multifunctional Thio-Stabilized Gold Nanoparticles for Near-Infrared Fluorescence Detection and Imaging of Activated Caspase-3.
Lung Neoplasms
NDRG1 Downregulates ATF3 and Inhibits Cisplatin-Induced Cytotoxicity in Lung Cancer A549 Cells.
Lung Neoplasms
Network Pharmacology Study on the Pharmacological Mechanism of Cinobufotalin Injection against Lung Cancer.
Lung Neoplasms
Nimesulide, a selective COX-2 inhibitor, acts synergistically with ionizing radiation against A549 human lung cancer cells through the activation of caspase-8 and caspase-3.
Lung Neoplasms
Novel approaches to cancer therapy with ibuprofen-loaded Eudragit® RS 100 and/or octadecylamine-modified PLGA nanoparticles by assessment of their effects on apoptosis.
Lung Neoplasms
NSC746364, a G-quadruplex-stabilizing agent, suppresses cell growth of A549 human lung cancer cells through activation of the ATR/Chk1-dependent pathway.
Lung Neoplasms
Obtusilactone A and (-)-sesamin induce apoptosis in human lung cancer cells by inhibiting mitochondrial Lon protease and activating DNA damage checkpoints.
Lung Neoplasms
Oncolytic newcastle disease virus triggers cell death of lung cancer spheroids and is enhanced by pharmacological inhibition of autophagy.
Lung Neoplasms
Overexpression of smac promotes Cisplatin-induced apoptosis by activating caspase-3 and caspase-9 in lung cancer a549 cells.
Lung Neoplasms
P-glycoprotein-independent apoptosis induction by a novel synthetic compound, MMPT [5-[(4-methylphenyl)methylene]-2-(phenylamino)-4(5H)-thiazolone].
Lung Neoplasms
p53 cooperates berberine-induced growth inhibition and apoptosis of non-small cell human lung cancer cells in vitro and tumor xenograft growth in vivo.
Lung Neoplasms
Paclitaxel-induced apoptosis in non-small cell lung cancer cell lines is associated with increased caspase-3 activity.
Lung Neoplasms
Phoyunnanin E Induces Apoptosis of Non-small Cell Lung Cancer Cells via p53 Activation and Down-regulation of Survivin.
Lung Neoplasms
Pinecone of Pinus koraiensis Inducing Apoptosis in Human Lung Cancer Cells by Activating Caspase-3 and its Chemical Constituents.
Lung Neoplasms
Polyvinyl pyrrolidone-coated silver nanoparticles in a human lung cancer cells: time- and dose-dependent influence over p53 and caspase-3 protein expression and epigenetic effects.
Lung Neoplasms
Ponicidin, an Ent-Kaurane Diterpenoid Derived from a Constituent of the Herbal Supplement PC-SPES, Rabdosia rubescens, Induces Apoptosis by Activation of Caspase-3 and Mitochondrial Events in Lung Cancer Cells In Vitro.
Lung Neoplasms
Prognostic assessment of apoptotic gene polymorphisms in non-small cell lung cancer in Chinese.
Lung Neoplasms
Prognostic relevance of c-Myc and caspase-3 for patients with non-small cell lung cancer.
Lung Neoplasms
Purpurin, a anthraquinone induces ROS-mediated A549 lung cancer cell apoptosis via inhibition of PI3K/AKT and proliferation.
Lung Neoplasms
Rare Chromone Derivatives from the Marine-Derived Penicillium citrinum with Anti-Cancer and Anti-Inflammatory Activities.
Lung Neoplasms
Receptor for hyaluronic acid-mediated motility (RHAMM, CD168) expression is prognostically important in both nodal negative and nodal positive large cell lung cancer.
Lung Neoplasms
Regulation of cytotoxicity and apoptosis-associated pathways contributes to the enhancement of efficacy of cisplatin by baicalein adjuvant in human A549 lung cancer cells.
Lung Neoplasms
Relationship between the expression of caspase-3 and the clinical outcome of patients with non-small cell lung cancer.
Lung Neoplasms
Replication-dependent ?-H2AX formation is involved in docetaxel-induced apoptosis in NSCLC A549 cells.
Lung Neoplasms
Resistance to caspase-8 and -9 fragments in a malignant pleural mesothelioma cell line with acquired cisplatin-resistance.
Lung Neoplasms
RNAi targeting STMN alleviates the resistance to taxol and collectively contributes to down regulate the malignancy of NSCLC cells in vitro and in vivo.
Lung Neoplasms
Role of Caspases, Bax and Bcl-2 in Chrysin-Induced Apoptosis in the A549 Human Lung Adenocarcinoma Epithelial Cells.
Lung Neoplasms
Role of Surface Hydrophobicity of Dicationic Amphiphile-Stabilized Gold Nanoparticles on A549 Lung Cancer Cells.
Lung Neoplasms
Role of XIAP in inhibiting cisplatin-induced caspase activation in non-small cell lung cancer cells: a small molecule Smac mimic sensitizes for chemotherapy-induced apoptosis by enhancing caspase-3 activation.
Lung Neoplasms
Safrole oxide induces apoptosis by activating caspase-3, -8, and -9 in A549 human lung cancer cells.
Lung Neoplasms
Safrole oxide induces apoptosis by up-regulating Fas and FasL instead of integrin beta4 in A549 human lung cancer cells.
Lung Neoplasms
Saikosaponin D inhibits proliferation and induces apoptosis of non-small cell lung cancer cells by inhibiting the STAT3 pathway.
Lung Neoplasms
SEP enhanced the antitumor activity of 5-fluorouracil by up-regulating NKG2D/MICA and reversed immune suppression via inhibiting ROS and caspase-3 in mice.
Lung Neoplasms
SHCBP1 regulates apoptosis in lung cancer cells through phosphatase and tensin homolog.
Lung Neoplasms
Stimulatory heterotrimeric G protein augments gamma ray-induced apoptosis by up-regulation of Bak expression via CREB and AP-1 in H1299 human lung cancer cells.
Lung Neoplasms
Sulindac enhances adenoviral vector expressing mda-7/IL-24-mediated apoptosis in human lung cancer.
Lung Neoplasms
Sustainability of CD24 expression, cell proliferation and migration, cisplatin-resistance, and caspase-3 expression during mesenchymal-epithelial transition induced by the removal of TGF-?1 in A549 lung cancer cells.
Lung Neoplasms
Synthesis of 5-Alknyltetrandrine Derivatives and Evaluation of Their Anticancer Activity on A549 Cell Lines.
Lung Neoplasms
Tetramethylpyrazine (TMPZ) triggers S-phase arrest and mitochondria-dependent apoptosis in lung cancer cells.
Lung Neoplasms
The effects of (12)c(6+) irradiation on cell cycle, apoptosis, and expression of caspase-3 in the human lung cancer cell line h1299.
Lung Neoplasms
The effects of cordycepin on the cell proliferation, migration and apoptosis in human lung cancer cell lines A549 and NCI-H460.
Lung Neoplasms
The preventive effects of hyperoside on lung cancer in vitro by inducing apoptosis and inhibiting proliferation through Caspase-3 and P53 signaling pathway.
Lung Neoplasms
The role of caspase 3 in producing cytokeratin 19 fragment (CYFRA21-1) in human lung cancer cell lines.
Lung Neoplasms
The therapeutic role of inhibition of miR-328 on pulmonary carcinoma induced by chlamydia pneumoniae through targeting histone H2AX.
Lung Neoplasms
The tumor suppressor gene RBM5 inhibits lung adenocarcinoma cell growth and induces apoptosis.
Lung Neoplasms
TIPE2 Inhibits Lung Cancer Growth Attributing to Promotion of Apoptosis by Regulating Some Apoptotic Molecules Expression.
Lung Neoplasms
TRAIL, FasL and a blocking anti-DR5 antibody augment paclitaxel-induced apoptosis in human non-small-cell lung cancer.
Lung Neoplasms
Transfer of IkappaBalpha gene increase the sensitivity of paclitaxel mediated with caspase 3 activation in human lung cancer cell.
Lung Neoplasms
Triptolide potentiates lung cancer cells to cisplatin-induced apoptosis by selectively inhibiting the NER activity.
Lung Neoplasms
Triptolide suppresses the in vitro and in vivo growth of lung cancer cells by targeting hyaluronan-CD44/RHAMM signaling.
Lung Neoplasms
Tumor suppressor in lung cancer-1 (TSLC1) mediated by dual-regulated oncolytic adenovirus exerts specific antitumor actions in a mouse model.
Lung Neoplasms
Volatile oil from alpinia officinarum promotes lung cancer regression in vitro and in vivo.
Lung Neoplasms
WITHDRAWN: Expression analysis of Sca-1 and its significance in lung cancers.
Lung Neoplasms
[Apoptosis of human lung cancer cells induced by activated peroxisome proliferator-activated receptor-gamma and its mechanism]
Lung Neoplasms
[Apoptosis-inducing effect of Scutellaria barbata extract on human lung cancer SPC-A-1 cells and the expression of apoptosis associated genes]
Lung Neoplasms
[Effect of supplement energy and nourish lung herbs on drug-resistance lung cancer with mechanisms of mitochondrial and caspase signal]
Lung Neoplasms
[Expression and significance of PCNA and Caspase-3 in the tissue of lung cancer]
Lung Neoplasms
[Expression of apoptosis and proliferation related genes in carcinogenesis of lung squamous cell carcinoma in rats]
Lung Neoplasms
[Expression of livin in lung cancer tissue and its relationship with the expression of caspase-3.]
Lung Neoplasms
[Expressions of survivin and caspase-3 in human non-small cell lung cancer and their relationship with cell apoptosis.]
Lung Neoplasms
[Molecular mechanism of Spatholobi Caulis in treatment of lung cancer based on network pharmacology and molecular docking].
Lung Neoplasms
[Proliferation and apoptosis of lung cancer cells regulated by gultaredoxin 3].
Lung Neoplasms
[Roles of cyclooxygenase-2 and caspase-3 expression in pathogenesis of lung carcinoma: an experiment with rats]
Lupus Erythematosus, Systemic
Increased caspase-3 expression and activity contribute to reduced CD3zeta expression in systemic lupus erythematosus T cells.
Lupus Nephritis
Immunohistochemical expression of activated caspase-3 as a marker of apoptosis in glomeruli of human lupus nephritis.
Lupus Nephritis
Increased apoptosis and expression of FasL, Bax and caspase-3 in human lupus nephritis class II and IV.
Lupus Nephritis
Nephritogenic lupus antibodies recognize glomerular basement membrane-associated chromatin fragments released from apoptotic intraglomerular cells.
Lupus Nephritis
[Apoptosis and expressions of PDCD5 and Caspase-3 in renal tissues of children with lupus nephritis]
Lymphadenitis
Apoptosis- and cell cycle-associated gene expression profiling of histiocytic necrotising lymphadenitis.
Lymphadenitis
Differential expression of mycobacterial antigen MPT64, apoptosis and inflammatory markers in multinucleated giant cells and epithelioid cells in granulomas caused by Mycobacterium tuberculosis.
Lymphatic Metastasis
Blocking circ_0013912 Suppressed Cell Growth, Migration and Invasion of Pancreatic Ductal Adenocarcinoma Cells in vitro and in vivo Partially Through Sponging miR-7-5p.
Lymphatic Metastasis
Clinicopathological and prognostic significance of Ki-67, caspase-3 and p53 expression in gastric carcinomas.
Lymphatic Metastasis
Expression of caspase-3 and hypoxia inducible factor 1? in hepatocellular carcinoma complicated by hemorrhage and necrosis.
Lymphatic Metastasis
Expression of p-Akt in ovarian serous carcinoma and its association with proliferation and apoptosis.
Lymphatic Metastasis
Expression of PTEN and Caspase-3 and their clinicopathological significance in primary gastric malignant lymphoma.
Lymphatic Metastasis
Expression of SIRT1 and apoptosis-related proteins is predictive for lymph node metastasis and disease-free survival in luminal A breast cancer.
Lymphatic Metastasis
Identification of potential prognostic markers for vulvar cancer using immunohistochemical staining of tissue microarrays.
Lymphatic Metastasis
Knockdown of Livin inhibits growth and invasion of gastric cancer cells through blockade of the MAPK pathway in vitro and in vivo.
Lymphatic Metastasis
The down-regulated ING5 expression in lung cancer: A potential target of gene therapy.
Lymphatic Metastasis
[Expression and significance of PCNA and Caspase-3 in the tissue of lung cancer]
Lymphatic Metastasis
[Expression of Survivin mRNA and Caspase-3 mRNA and their correlation in tongue squamous cell carcinoma]
Lymphoma
13 Cis-retinoic acid mediates apoptosis in Dalton's lymphoma ascites cells by regulating gene expression.
Lymphoma
17?-estradiol protects against doxorubicin-induced cardiotoxicity in male Sprague-Dawley rats by regulating NADPH oxidase and apoptosis genes.
Lymphoma
3,3'?Diindolylmethane attenuates cardiomyocyte hypoxia by modulating autophagy in H9c2 cells.
Lymphoma
A Litopenaeus vannamei Hemocyanin-Derived Antimicrobial Peptide (Peptide B11) Attenuates Cancer Cells' Proliferation.
Lymphoma
A novel therapeutic strategy against monocytic leukemia with deoxyadenosine analogs and adenosine deaminase inhibitors.
Lymphoma
A polysaccharide from the fruiting bodies of Agaricus blazei Murill induces caspase-dependent apoptosis in human leukemia HL-60 cells.
Lymphoma
A role for nuclear translocation of tripeptidyl-peptidase II in reactive oxygen species-dependent DNA damage responses.
Lymphoma
Acteoside Attenuates Oxidative Stress and Neuronal Apoptosis in Rats with Focal Cerebral Ischemia-Reperfusion Injury.
Lymphoma
Activation of the Notch?Nox4?reactive oxygen species signaling pathway induces cell death in high glucose?treated human retinal endothelial cells.
Lymphoma
Adiponectin agonist ADP355 ameliorates doxorubicin-induced cardiotoxicity by decreasing cardiomyocyte apoptosis and oxidative stress.
Lymphoma
Anesthetic isoflurane posttreatment attenuates experimental lung injury by inhibiting inflammation and apoptosis.
Lymphoma
Angiodestruction and tissue necrosis of skin-involving CD56+ NK/T-cell lymphoma are influenced by expression of cell adhesion molecules and cytotoxic granule and apoptosis-related proteins.
Lymphoma
Anthocyanins from Lycium ruthenicum Murr. Ameliorated d-Galactose-Induced Memory Impairment, Oxidative Stress, and Neuroinflammation in Adult Rats.
Lymphoma
Anti-inflammatory and anti-apoptotic effects of oxysophoridine on lipopolysaccharide-induced acute lung injury in mice.
Lymphoma
Anti-neuroinflammatory and neuroprotective effects of the Lindera neesiana fruit in vitro.
Lymphoma
Anticancer effect of resibufogenin on gastric carcinoma cells through the phosphoinositide 3-kinase/protein kinase B/glycogen synthase kinase 3? signaling pathway.
Lymphoma
Anticancer Effect of Ursodeoxycholic Acid in Human Oral Squamous Carcinoma HSC-3 Cells through the Caspases.
Lymphoma
Antrodia salmonea induces apoptosis and enhances cytoprotective autophagy in colon cancer cells.
Lymphoma
Antrodia salmonea-induced oxidative stress abrogates HER-2 signaling cascade and enhanced apoptosis in ovarian carcinoma cells.
Lymphoma
Apigenin Ameliorates Scopolamine-Induced Cognitive Dysfunction and Neuronal Damage in Mice.
Lymphoma
Apoptosis and expression of caspases 3, 6 and 8 in malignant non-Hodgkin's lymphomas.
Lymphoma
Apoptosis in B-cell lymphomas and reactive lymphoid tissues always involves activation of caspase 3 as determined by a new in situ detection method.
Lymphoma
Arsenic trioxide induces apoptosis of cutaneous T cell lymphoma cells: evidence for a partially caspase-independent pathway and potentiation by ascorbic acid (vitamin C).
Lymphoma
Arsenic trioxide-induced apoptosis of human malignant lymphoma cell lines and its mechanisms.
Lymphoma
Asteriscus graveolens Extract in Combination with Cisplatin/Etoposide/Doxorubicin Suppresses Lymphoma Cell Growth through Induction of Caspase-3 Dependent Apoptosis.
Lymphoma
ATF6 knockdown decreases apoptosis, arrests the S phase of the cell cycle, and increases steroid hormone production in mouse granulosa cells.
Lymphoma
Atractylenolide I alleviates ischemia/reperfusion injury by preserving mitochondrial function and inhibiting caspase-3 activity.
Lymphoma
Attenuation of High Glucose-Induced Rat Cardiomyocyte Apoptosis by Exendin-4 via Intervention of HO-1/Nrf-2 and the PI3K/AKT Signaling Pathway.
Lymphoma
Autophagy contributes to apoptosis in A20 and EL4 lymphoma cells treated with fluvastatin.
Lymphoma
Blocking HOTAIR protects human chondrocytes against IL-1?-induced cell apoptosis, ECM degradation, inflammatory response and oxidative stress via regulating miR-222-3p/ADAM10 axis.
Lymphoma
Bone morphogenetic protein 9 facilitates osteocarcinoma cell apoptosis and inhibits in vivo tumor growth.
Lymphoma
BOS-93, a novel bromophenol derivative, induces apoptosis and autophagy in human A549 lung cancer cells via PI3K/Akt/mTOR and MAPK signaling pathway.
Lymphoma
Cannabinoid receptor agonist WIN55,212-2 and fatty acid amide hydrolase inhibitor URB597 suppress chronic cerebral hypoperfusion-induced neuronal apoptosis by inhibiting c-Jun N-terminal kinase signaling.
Lymphoma
Carbon monoxide releasing molecule-2 suppresses proliferation, migration, invasion, and promotes apoptosis in non-small cell lung cancer Calu-3 cells.
Lymphoma
Caspase 3-mediated inactivation of rac GTPases promotes drug-induced apoptosis in human lymphoma cells.
Lymphoma
Chemo-Protective Potential of Cerium Oxide Nanoparticles against Fipronil-Induced Oxidative Stress, Apoptosis, Inflammation and Reproductive Dysfunction in Male White Albino Rats.
Lymphoma
Chronic Akt activation attenuated lipopolysaccharide-induced cardiac dysfunction via Akt/GSK3?-dependent inhibition of apoptosis and ER stress.
Lymphoma
Circular RNA Circ_ANKMY2 Regulates Temporal Lobe Epilepsy Progression via the miR-106b-5p/FOXP1 Axis.
Lymphoma
Circulating fragmented nucleosomal DNA and caspase-3 mRNA in patients with lymphoma and myeloma.
Lymphoma
Clinicopathologic differences between 22 cases of CD56-negative and CD56-positive subcutaneous panniculitis-like lymphoma in Japan.
Lymphoma
Critical Impact of Human Amniotic Membrane Tension on Mitochondrial Function and Cell Viability In Vitro.
Lymphoma
Cyclamin, a natural 13,28-epoxy triterpenoid saponin, synergistically enhances the cytotoxicity of chemotherapeutic drugs in human liver cancer cells but not non-neoplastic liver cells.
Lymphoma
Cytochrome c release, mitochondrial membrane depolarization, caspase-3 activation, and Bax-alpha cleavage during IFN-alpha-induced apoptosis in Daudi B lymphoma cells.
Lymphoma
Cytoplasmic location of NR4A1 in aggressive lymphomas is associated with a favourable cancer specific survival.
Lymphoma
Cytotoxicity of Gymnopilus purpureosquamulosus extracts on hematologic malignant cells through activation of the SAPK/JNK signaling pathway.
Lymphoma
Deciphering the molecular pathways of apoptosis using purified fractions from leaf extract of Basella alba through studying the regulation of apoptosis related genes.
Lymphoma
Design, synthesis, and application of OB2C combinatorial peptide and peptidomimetic libraries.
Lymphoma
Different radiosensitivity of CD4(+)CD25(+) regulatory T cells and effector T cells to low dose gamma irradiation in vitro.
Lymphoma
Distinct role of CD80 and CD86 in the regulation of the activation of B cell and B cell lymphoma.
Lymphoma
E mu-bcl-2 transgene facilitates spontaneous transformation of early pre-B and immunoglobulin-secreting cells but not T cells.
Lymphoma
Eaf2 protects human lens epithelial cells against oxidative stress?induced apoptosis by Wnt signaling.
Lymphoma
Effect of alterations in apoptotic pathway on development of metabolic syndrome in patients with psoriasis vulgaris.
Lymphoma
Effect of limb ischemic preconditioning on myocardial apoptosis-related proteins in ischemia-reperfusion injury.
Lymphoma
Effect of selective inhibition of aquaporin 1 on chemotherapy sensitivity of J82 human bladder cancer cells.
Lymphoma
Effects of ellagic acid on chemosensitivity to 5-fluorouracil in colorectal carcinoma cells.
Lymphoma
Endoplasmic Reticulum Stress and Neurodegeneration in Experimental Cerebral Malaria.
Lymphoma
Epstein-Barr virus-mediated protection against etoposide-induced apoptosis in BJA-B B cell lymphoma cells: role of Bcl-2 and caspase proteins.
Lymphoma
Estimation of the relationship between caspase-3 expression and clinical outcome of Burkitt's and Burkitt-like lymphoma.
Lymphoma
Ethanol extract of Ligustrum lucidum Ait. leaves suppressed hepatocellular carcinoma in vitro and in vivo.
Lymphoma
Evaluation of Anti-inflammatory and Regenerative Efficiency of Naringin and Naringenin in Degenerated Human Nucleus Pulposus Cells: Biological and Molecular Modeling Studies.
Lymphoma
Exogenous vascular endothelial growth factor delivery prior to endothelial precursor cell transplantation in orthotopic liver transplantation-induced hepatic ischemia/reperfusion injury.
Lymphoma
Expression levels of apoptosis-related proteins predict clinical outcome in anaplastic large cell lymphoma.
Lymphoma
Expression of bcl2 family proteins and active caspase 3 in classical Hodgkin's lymphomas.
Lymphoma
Expression of PTEN and Caspase-3 and their clinicopathological significance in primary gastric malignant lymphoma.
Lymphoma
Expression of the granzyme B inhibitor PI9 predicts outcome in nasal NK/T-cell lymphoma: results of a Western series of 48 patients treated with first-line polychemotherapy within the Groupe d'Etude des Lymphomes de l'Adulte (GELA) trials.
Lymphoma
Extracellular Vesicles Derived from Wharton's Jelly Mesenchymal Stem Cells Prevent and Resolve Programmed Cell Death Mediated by Perinatal Hypoxia-Ischemia in Neuronal Cells.
Lymphoma
FADD expression and caspase activation in B-cell lymphomas resistant to Fas-mediated apoptosis.
Lymphoma
Flavonoid Naringenin Attenuates Oxidative Stress, Apoptosis and Improves Neurotrophic Effects in the Diabetic Rat Retina.
Lymphoma
Frequent nuclear localization of ICAD and cytoplasmic co-expression of caspase-8 and caspase-3 in human lymphomas.
Lymphoma
Functional characterization of the nitrogen permease regulator-like-2 candidate tumor suppressor gene in colorectal cancer cell lines.
Lymphoma
Furosine Induced Apoptosis by the Regulation of STAT1/STAT2 and UBA7/UBE2L6 Genes in HepG2 Cells.
Lymphoma
Gastrodin Alleviates Cerebral Ischemic Damage in Mice by Improving Anti-oxidant and Anti-inflammation Activities and Inhibiting Apoptosis Pathway.
Lymphoma
Generation of rituximab polymer may cause hyper-cross-linking-induced apoptosis in non-Hodgkin's lymphomas.
Lymphoma
Granzyme B leakage-induced apoptosis is a crucial mechanism of cell death in nasal-type NK/T-cell lymphoma.
Lymphoma
GSK-3? inhibitor, 9-ING-41, reduces cell viability and halts proliferation of B-cell lymphoma cell lines as a single agent and in combination with novel agents.
Lymphoma
Hepatocellular toxicity of oxalicumone A via oxidative stress injury and mitochondrial dysfunction in healthy human liver cells.
Lymphoma
Hesperetin induces apoptosis of esophageal cancer cells via mitochondrial pathway mediated by the increased intracellular reactive oxygen species.
Lymphoma
HMG-CoA reductase inhibitors induce apoptosis of lymphoma cells by promoting ROS generation and regulating Akt, Erk and p38 signals via suppression of mevalonate pathway.
Lymphoma
Hsp27 (HSPB1) differential expression in normal salivary glands and pleomorphic adenomas and association with an increased Bcl2/Bax ratio.
Lymphoma
Human bocavirus induces apoptosis and autophagy in human bronchial epithelial cells.
Lymphoma
Human monocytoid leukemia cells are highly sensitive to apoptosis induced by 2'-deoxycoformycin and 2'-deoxyadenosine: association with dATP-dependent activation of caspase-3.
Lymphoma
Hydroxysafflor Yellow A mitigated myocardial ischemia/reperfusion injury by inhibiting the activation of the JAK2/STAT1 pathway.
Lymphoma
Hyperoside Attenuates Hepatic Ischemia-Reperfusion Injury by Suppressing Oxidative Stress and Inhibiting Apoptosis in Rats.
Lymphoma
Ibuprofen abates cypermethrin-induced expression of pro-inflammatory mediators and mitogen-activated protein kinases and averts the nigrostriatal dopaminergic neurodegeneration.
Lymphoma
Immune thrombocytopenia induces autophagy and suppresses apoptosis in megakaryocytes.
Lymphoma
Immunohistochemical analysis of cleaved caspase-3 detects high level of apoptosis frequently in diffuse large B-cell lymphomas of the central nervous system.
Lymphoma
Immunohistochemical analysis of interleukin-1beta-converting enzyme/Ced-3 family protease, CPP32/Yama/Caspase-3, in Hodgkin's disease.
Lymphoma
Immunohistochemical expression of procaspase-3 and its clinical significance in childhood non-Hodgkin lymphomas.
Lymphoma
Immunohistochemical localization of caspase-3 correlates with clinical outcome in B-cell diffuse large-cell lymphoma.
Lymphoma
Immunohistochemistry of programmed cell death in archival human pathology specimens.
Lymphoma
Immunolocalization of the ICE/Ced-3-family protease, CPP32 (Caspase-3), in non-Hodgkin's lymphomas, chronic lymphocytic leukemias, and reactive lymph nodes.
Lymphoma
Inhibition of miR-153 ameliorates ischemia/reperfusion-induced cardiomyocytes apoptosis by regulating Nrf2/HO-1 signaling in rats.
Lymphoma
Inhibition of transcription factor NF-kappaB signaling proteins IKKbeta and p65 through specific cysteine residues by epoxyquinone A monomer: correlation with its anti-cancer cell growth activity.
Lymphoma
Investigating the Thioredoxin and Glutathione Systems' Response in Lymphoma Cells after Treatment with [Au(d2pype)2]CL.
Lymphoma
Investigation of highly expressed PCSK9 in atherosclerotic plaques and ox-LDL-induced endothelial cell apoptosis.
Lymphoma
Involvement of Bax, Bcl-2 and caspase 3 in hydroxyurea- or etoposide-induced apoptosis of mouse interleukin-3-dependent lymphoma cells.
Lymphoma
Irradiation as preparative regimen for hepatocyte transplantation causes prolonged cell cycle block.
Lymphoma
Jesterone dimer, a synthetic derivative of the fungal metabolite jesterone, blocks activation of transcription factor nuclear factor kappaB by inhibiting the inhibitor of kappaB kinase.
Lymphoma
Knockdown of long noncoding RNA XIST mitigates the apoptosis and inflammatory injury of microglia cells after spinal cord injury through miR-27a/Smurf1 axis.
Lymphoma
L-carnitine inhibits apoptotic DNA fragmentation induced by a new spin-labeled derivative of podophyllotoxin via caspase-3 in Raji cells.
Lymphoma
Lentivirus-mediated silencing of HOTAIR lncRNA restores gefitinib sensitivity by activating Bax/Caspase-3 and suppressing TGF-?/EGFR signaling in lung adenocarcinoma.
Lymphoma
Levistolide A synergistically enhances doxorubicin?induced apoptosis of k562/dox cells by decreasing MDR1 expression through the ubiquitin pathway.
Lymphoma
LFG-500, a newly synthesized flavonoid, induces apoptosis in human ovarian carcinoma SKOV3 cells with involvement of the reactive oxygen species-mitochondria pathway.
Lymphoma
Ligation of CD40 potentiates Fas-mediated activation of the cysteine protease CPP32, cleavage of its death substrate PARP, and apoptosis in Ramos-Burkitt lymphoma B cells.
Lymphoma
Ligustrazine suppresses neuron apoptosis via the Bax/Bcl-2 and caspase-3 pathway in PC12 cells and in rats with vascular dementia.
Lymphoma
Losartan improves erectile function through suppression of corporal apoptosis and oxidative stress in rats with cavernous nerve injury.
Lymphoma
Lym-1-induced apoptosis of non-Hodgkin's lymphomas produces regression of transplanted tumors.
Lymphoma
Melatonin Attenuates AlCl3-Induced Apoptosis and Osteoblastic Differentiation Suppression by Inhibiting Oxidative Stress in MC3T3-E1 Cells.
Lymphoma
Melatonin Improves Endoplasmic Reticulum Stress-Mediated IRE1? Pathway in Zücker Diabetic Fatty Rat.
Lymphoma
Methylene Blue Exerts Anticonvulsant and Neuroprotective Effects on Self-Sustaining Status Epilepticus (SSSE) Induced by Prolonged Basolateral Amygdala Stimulation in Wistar Rats.
Lymphoma
MicroRNA-140 inhibits skeletal muscle glycolysis and atrophy in endotoxin-induced sepsis in mice via the WNT signaling pathway.
Lymphoma
MicroRNA-744 promotes cell apoptosis via targeting B cell lymphoma-2 in gastric cancer cell line SGC-7901.
Lymphoma
MiR-20b promotes osteocyte apoptosis in rats with steroid-induced necrosis of the femoral head through BMP signaling pathway.
Lymphoma
miR-340 Inhibits Proliferation and Induces Apoptosis in Gastric Cancer Cell Line SGC-7901, Possibly via the AKT Pathway.
Lymphoma
miR-378a-5p and miR-630 induce lens epithelial cell apoptosis in cataract via suppression of E2F3.
Lymphoma
MiR-499a suppresses LPS-induced human vascular endothelial cell inflammatory response and apoptosis by regulating STAT1.
Lymphoma
mTOR inhibition as a possible pharmacological target in the management of systemic inflammatory response and associated neuroinflammation by lipopolysaccharide challenge in rats.
Lymphoma
Myricetin induces cell death of human colon cancer cells via BAX/BCL2-dependent pathway.
Lymphoma
Nanofluidic proteomic assay for serial analysis of oncoprotein activation in clinical specimens.
Lymphoma
Native macrophages genetically modified to express heme oxygenase 1 protect rat liver transplants from ischemia/reperfusion injury.
Lymphoma
Neuroprotective effects of different frequency preconditioning exercise on neuronal apoptosis after focal brain ischemia in rats.
Lymphoma
New Acetohydrazides Incorporating 2-Oxoindoline and 4-Oxoquinazoline: Synthesis and Evaluation of Cytotoxicity and Caspase Activation Activity.
Lymphoma
Nimbolide induces cell death in T lymphoma cells: Implication of altered apoptosis and glucose metabolism.
Lymphoma
Nimesulide inhibits proliferation and induces apoptosis of pancreatic cancer cells by enhancing expression of PTEN.
Lymphoma
Norcantharidin Inhibits SK-N-SH Neuroblastoma Cell Growth by Induction of Autophagy and Apoptosis.
Lymphoma
Overexpression of Shrm4 promotes proliferation and differentiation of neural stem cells through activation of GABA signaling pathway.
Lymphoma
Pancratistatin causes early activation of caspase-3 and the flipping of phosphatidyl serine followed by rapid apoptosis specifically in human lymphoma cells.
Lymphoma
Paradoxical effect of testosterone supplementation therapy on cardiac ischemia/reperfusion injury in aged rats.
Lymphoma
Peptides from anchovy sauce induce apoptosis in a human lymphoma cell (U937) through the increase of caspase-3 and -8 activities.
Lymphoma
Phyllanthus Amarus Inhibits Cell Growth and Induces Apoptosis in Dalton?s Lymphoma Ascites Cells Through Activation of Caspase 3 and Down Regulation of bcl-2.
Lymphoma
Polyunsaturated fatty acids induce cell death in YAC-1 lymphoma by a caspase-3-independent mechanism.
Lymphoma
Postmortem expression of apoptosis-related genes in the liver of mice and their use for estimation of the time of death.
Lymphoma
Prenatal exposure to di-n-butyl phthalate induces erectile dysfunction in male adult rats.
Lymphoma
Pretreatment with 2-(4-methoxyphenyl)ethyl-2-acetamido-2-deoxy-?-D-pyranoside attenuates cerebral ischemia/reperfusion-induced injury in vitro and in vivo.
Lymphoma
Protective skin aging effects of cherry blossom extract (Prunus Yedoensis) on oxidative stress and apoptosis in UVB-irradiated HaCaT cells.
Lymphoma
Pyrvinium selectively induces apoptosis of lymphoma cells through impairing mitochondrial functions and JAK2/STAT5.
Lymphoma
Qilin pills alleviate oligoasthenospermia by inhibiting Bax-caspase-9 apoptosis pathway in the testes of model rats.
Lymphoma
Regulation of Caspase-3 and Bcl-2 Expression in Dalton's Lymphoma Ascites Cells by Abrin.
Lymphoma
Role and mechanism of hypoxia-inducible factor-1 in cell growth and apoptosis of breast cancer cell line MDA-MB-231.
Lymphoma
Role of ellagic acid in regulation of apoptosis by modulating novel and atypical PKC in lymphoma bearing mice.
Lymphoma
Role of intracellular calcium ions and reactive oxygen species in apoptosis induced by ultrasound.
Lymphoma
Sanguinarine inhibits angiotensin II-induced apoptosis in H9c2 cardiac cells via restoring reactive oxygen species-mediated decreases in the mitochondrial membrane potential.
Lymphoma
Sequential activation of ICE-like and CPP32-like proteases during Fas-mediated apoptosis.
Lymphoma
Sodium tanshinone IIA sulfonate prevents radiation-induced damage in primary rat cardiac fibroblasts.
Lymphoma
Soursop fruit extract mitigates scopolamine-induced amnesia and oxidative stress via activating cholinergic and Nrf2/HO-1 pathways.
Lymphoma
Strong anticancer potential of nano-triterpenoid from Phytolacca decandra against A549 adenocarcinoma via a Ca(2+)-dependent mitochondrial apoptotic pathway.
Lymphoma
Synthesis, characterization and antitumor activity of Ln(III) complexes with hydrazone Schiff base derived from 2-acetylpyridine and isonicotinohydrazone.
Lymphoma
Systems Network Genomic Analysis Reveals Cardioprotective Effect of MURC/Cavin-4 Deletion Against Ischemia/Reperfusion Injury.
Lymphoma
TAT cell-penetrating peptide modulates inflammatory response and apoptosis in human lung epithelial cells.
Lymphoma
Taurine Pretreatment Prevents Isoflurane-Induced Cognitive Impairment by Inhibiting ER Stress-Mediated Activation of Apoptosis Pathways in the Hippocampus in Aged Rats.
Lymphoma
The Anti-Cancer Effect of Linusorb B3 from Flaxseed Oil through the Promotion of Apoptosis, Inhibition of Actin Polymerization, and Suppression of Src Activity in Glioblastoma Cells.
Lymphoma
The antioxidant edaravone prevents cardiac dysfunction by suppressing oxidative stress in type 1 diabetic rats and in high-glucose-induced injured H9c2 cardiomyoblasts.
Lymphoma
The cardioprotective effects of diallyl trisulfide on diabetic rats with ex vivo induced ischemia/reperfusion injury.
Lymphoma
The In Vitro and In Vivo Anticancer Properties of Chalcone Flavokawain B through Induction of ROS-Mediated Apoptotic and Autophagic Cell Death in Human Melanoma Cells.
Lymphoma
The Inhibition Effect of the Seaweed Polyphenol, 7-Phloro-Eckol from Ecklonia Cava on Alcohol-Induced Oxidative Stress in HepG2/CYP2E1 Cells.
Lymphoma
The Molecular Evolution and Functional Divergence of Lamprey Programmed Cell Death Genes.
Lymphoma
The protective effects of exogenous spermine on renal ischemia-reperfusion injury in rats.
Lymphoma
The Protective Role of Selenium Against AFB1-Induced Liver Apoptosis by Death Receptor Pathway in Broilers.
Lymphoma
The renoprotective effects of naringin and trimetazidine on renal ischemia/reperfusion injury in rats through inhibition of apoptosis and downregulation of micoRNA-10a.
Lymphoma
Three mutations in v-Rel render it resistant to cleavage by cell-death protease caspase-3.
Lymphoma
Triptonide acts as a novel potent anti-lymphoma agent with low toxicity mainly through inhibition of proto-oncogene Lyn transcription and suppression of Lyn signal pathway.
Lymphoma
Tumor control in a model of bone marrow transplantation and acute liver-infiltrating B-cell lymphoma: an unpredicted novel function of cytomegalovirus.
Lymphoma
Upregulation of phosphatase and tensin homolog is essential for the effect of 4-aminopyridine on A549/CDDP cells.
Lymphoma
Vaccarin alleviates hypertension and nephropathy in renovascular hypertensive rats.
Lymphoma
Validation of tissue microarrays for immunohistochemical analyses of canine lymphomas.
Lymphoma
Vinorelbine induces apoptosis and caspase-3 (CPP32) expression in leukemia and lymphoma cells: a comparison with vincristine.
Lymphoma
Vitexin reverses the autophagy dysfunction to attenuate MCAO-induced cerebral ischemic stroke via mTOR/Ulk1 pathway.
Lymphoma
YAP knockdown inhibits proliferation and induces apoptosis of human prostate cancer DU145 cells.
Lymphoma
Zinc Protects against Heat Stress-Induced Apoptosis via the Inhibition of Endoplasmic Reticulum Stress in TM3 Leydig Cells.
Lymphoma
Zinc-mediated regulation of caspases activity: dose-dependent inhibition or activation of caspase-3 in the human Burkitt lymphoma B cells (Ramos).
Lymphoma
[Effect and mechanism of liraglutide on the apoptosis of human hepatocellular carcinoma HepG2 cells induced with palmitic acid].
Lymphoma
[Expression of Apoptosis-related Protein Livin and Caspase-3 in Diffuse Large B Cell Lymphoma and Its Clinical Significance].
Lymphoma
[Involvement of JNK and caspase-3 in human lymphoma cell apoptosis induced by Prunella vulgaris]
Lymphoma
[Study on expression of caspase-3 and bcl-2 proteins and their relations with cell apoptosis and proliferation in non-Hodgkin's lymphoma]
Lymphoma
[Up-Regulation of Bax/BCL-2 Ratio by 2-Methoxyestradiol Induces Apoptosis in Lymphoma Raji Cells].
Lymphoma, B-Cell
2?-Hydroxyeudesma-4,11(13)-Dien-8?,12-Olide Isolated from Inula britannica Induces Apoptosis in Diffuse Large B-cell Lymphoma Cells.
Lymphoma, B-Cell
3,3'?Diindolylmethane attenuates cardiomyocyte hypoxia by modulating autophagy in H9c2 cells.
Lymphoma, B-Cell
3,5-Diethoxy-3'-Hydroxyresveratrol (DEHR) Ameliorates Liver Fibrosis via Caveolin-1 Activation in Hepatic Stellate Cells and in a Mouse Model of Bile Duct Ligation Injury.
Lymphoma, B-Cell
3-Bromopyruvate inhibits human gastric cancer tumor growth in nude mice via the inhibition of glycolysis.
Lymphoma, B-Cell
8-Cetylcoptisine, a new coptisine derivative, induces mitochondria-dependent apoptosis and G0/G1 cell cycle arrest in human A549?cells.
Lymphoma, B-Cell
9-cis retinoic acid inhibits cumulus cell apoptosis during the maturation of bovine cumulus-oocyte-complexes.
Lymphoma, B-Cell
?-elemene enhances anticancer bone neoplasms efficacy of paclitaxel through regulation of GPR124 in bone neoplasms cells.
Lymphoma, B-Cell
A Novel Oral Astaxanthin Nanoemulsion from Haematococcus pluvialis Induces Apoptosis in Lung Metastatic Melanoma.
Lymphoma, B-Cell
A Novel Peptide from Vespa ducalis Induces Apoptosis in Osteosarcoma Cells by Activating the p38 MAPK and JNK Signaling Pathways.
Lymphoma, B-Cell
A Novel Role of SIRT1/ FGF-21 in Taurine Protection Against Cafeteria Diet-Induced Steatohepatitis in Rats.
Lymphoma, B-Cell
A study of regulatory effects of TLR4 and NF-?B on primary biliary cholangitis.
Lymphoma, B-Cell
Abscisic acid ameliorates oxidative stress, inflammation, and apoptosis in thioacetamide-induced hepatic fibrosis by regulating the NF-?B signaling pathway in mice.
Lymphoma, B-Cell
Acteoside Attenuates Oxidative Stress and Neuronal Apoptosis in Rats with Focal Cerebral Ischemia-Reperfusion Injury.
Lymphoma, B-Cell
Activation of nuclear factor erythroid 2-related factor 2 and PPAR? plays a role in the genistein-mediated attenuation of oxidative stress-induced endothelial cell injury.
Lymphoma, B-Cell
Acute effects of human protein S administration after traumatic brain injury in mice.
Lymphoma, B-Cell
Adenovirus-directed expression of TIPE2 suppresses gastric cancer growth via induction of apoptosis and inhibition of AKT and ERK1/2 signaling.
Lymphoma, B-Cell
Alendronate induces osteoclast precursor apoptosis via peroxisomal dysfunction mediated ER stress.
Lymphoma, B-Cell
Allantoin ameliorates chemically-induced pancreatic ?-cell damage through activation of the imidazoline I3 receptors.
Lymphoma, B-Cell
Allicin mitigates hepatic injury following cyclophosphamide administration via activation of Nrf2/ARE pathways and through inhibition of inflammatory and apoptotic machinery.
Lymphoma, B-Cell
Alsterpaullone induces apoptosis of HepG2 cells via a p38 mitogen-activated protein kinase signaling pathway.
Lymphoma, B-Cell
Altered apoptosis-related signaling after cardioplegic arrest in patients with uncontrolled type 2 diabetes mellitus.
Lymphoma, B-Cell
Ameliorative Effect of Graviola (Annona muricata) on Mono Sodium Glutamate-Induced Hepatic Injury in Rats: Antioxidant, Apoptotic, Anti-inflammatory, Lipogenesis Markers, and Histopathological Studies.
Lymphoma, B-Cell
Ameliorative effect of rosiglitazone, a peroxisome proliferator gamma agonist on adriamycin-induced cardio toxicity via suppressing oxidative stress and apoptosis.
Lymphoma, B-Cell
Ameliorative effects of crocin on paraquat-induced oxidative stress in testis of adult mice: An experimental study.
Lymphoma, B-Cell
Ammonia inhalation impaired immune function and mitochondrial integrity in the broilers bursa of fabricius: Implication of oxidative stress and apoptosis.
Lymphoma, B-Cell
Amygdalin Regulates Apoptosis and Adhesion in Hs578T Triple-Negative Breast Cancer Cells.
Lymphoma, B-Cell
Angiotensin-(1-7) Treatment Ameliorates Angiotensin II-Induced HUVEC Apoptosis.
Lymphoma, B-Cell
Anthocyanins from Lycium ruthenicum Murr. Ameliorated d-Galactose-Induced Memory Impairment, Oxidative Stress, and Neuroinflammation in Adult Rats.
Lymphoma, B-Cell
Anti-cancer effects of 2-oxoquinoline derivatives on the HCT116 and LoVo human colon cancer cell lines.
Lymphoma, B-Cell
Anti-Condyloma acuminata mechanism of microRNAs-375 modulates HPV in cervical cancer cells via the UBE3A and IGF-1R pathway.
Lymphoma, B-Cell
Anti-neuroinflammatory and neuroprotective effects of the Lindera neesiana fruit in vitro.
Lymphoma, B-Cell
Anti-Proliferative and Apoptotic Activities of Müllerian Inhibiting Substance Combined with Calcitriol in Ovarian Cancer Cell Lines.
Lymphoma, B-Cell
Anticancer Properties of Carnosol: A Summary of in Vitro and In Vivo Evidence.
Lymphoma, B-Cell
Anticancer Properties of Platinum Nanoparticles and Retinoic Acid: Combination Therapy for the Treatment of Human Neuroblastoma Cancer.
Lymphoma, B-Cell
Anticonvulsant effect of piperine ameliorates memory impairment, inflammation and oxidative stress in a rat model of pilocarpine-induced epilepsy.
Lymphoma, B-Cell
Antifibrotic effect of curcumin, n-acetyl cysteine and propolis against bisphenol A-induced hepatotoxicity in rats: Prophylaxis versus co-treatment.
Lymphoma, B-Cell
Antigen detection and apoptosis in Mongolian gerbil's kidney experimentally intraperitoneally infected by swine hepatitis E virus.
Lymphoma, B-Cell
Antioxidative and hepatoprotective activities of the ethyl acetate fraction separated from the fruit of Livistona chinensis.
Lymphoma, B-Cell
Apigenin Ameliorates Scopolamine-Induced Cognitive Dysfunction and Neuronal Damage in Mice.
Lymphoma, B-Cell
Apoptosis in B-cell lymphomas and reactive lymphoid tissues always involves activation of caspase 3 as determined by a new in situ detection method.
Lymphoma, B-Cell
Arctigenin induces necroptosis through mitochondrial dysfunction with CCN1 upregulation in prostate cancer cells under lactic acidosis.
Lymphoma, B-Cell
Arsenic trioxide induces apoptosis in the THP1 cell line by downregulating EVI-1.
Lymphoma, B-Cell
ATF6 knockdown decreases apoptosis, arrests the S phase of the cell cycle, and increases steroid hormone production in mouse granulosa cells.
Lymphoma, B-Cell
Atorvastatin inhibits cholesterol-induced caspase-3 cleavage through down-regulation of p38 and up-regulation of Bcl-2 in the rat carotid artery.
Lymphoma, B-Cell
Baicalein exerts neuroprotective effect against ischaemic/reperfusion injury via alteration of NF-kB and LOX and AMPK/Nrf2 pathway.
Lymphoma, B-Cell
Baicalin attenuates liver hypoxia/reoxygenation injury by inducing autophagy.
Lymphoma, B-Cell
Baicalin prevents tumor necrosis factor-?-induced apoptosis and dysfunction of pancreatic ?-cell line Min6 via upregulation of miR-205.
Lymphoma, B-Cell
Bax inhibitor-1 overexpression in prelimbic cortex protects rats against depression-like behavior induced by olfactory bulbectomy and reduces apoptotic and inflammatory signals.
Lymphoma, B-Cell
Beneficial Effects of Inflammatory Cytokine-Targeting Aptamers in an Animal Model of Chronic Prostatitis.
Lymphoma, B-Cell
Betulinic acid induces apoptosis and inhibits metastasis of human renal carcinoma cells in vitro and in vivo.
Lymphoma, B-Cell
Betulinic acid protects mice from cadmium chloride-induced toxicity by inhibiting cadmium-induced apoptosis in kidney and liver.
Lymphoma, B-Cell
Biological activity of Brassica rapa L. polysaccharides on RAW264.7 macrophages and on tumor cells.
Lymphoma, B-Cell
Bisdemethoxycurcumin attenuates gastric adenocarcinoma growth by inducing mitochondrial dysfunction.
Lymphoma, B-Cell
Blockade of Janus kinase-2 signaling ameliorates mouse liver damage due to ischemia and reperfusion.
Lymphoma, B-Cell
Blocking HOTAIR protects human chondrocytes against IL-1?-induced cell apoptosis, ECM degradation, inflammatory response and oxidative stress via regulating miR-222-3p/ADAM10 axis.
Lymphoma, B-Cell
BMAL1 Suppresses Proliferation, Migration, and Invasion of U87MG Cells by Downregulating Cyclin B1, Phospho-AKT, and Metalloproteinase-9.
Lymphoma, B-Cell
Bone morphogenetic protein-7 (BMP-7) mediates ischemic preconditioning-induced ischemic tolerance via attenuating apoptosis in rat brain.
Lymphoma, B-Cell
BOS-93, a novel bromophenol derivative, induces apoptosis and autophagy in human A549 lung cancer cells via PI3K/Akt/mTOR and MAPK signaling pathway.
Lymphoma, B-Cell
Bushen Zhuangjin decoction inhibits TM-induced chondrocyte apoptosis mediated by endoplasmic reticulum stress.
Lymphoma, B-Cell
C1 inhibitor-mediated myocardial protection from chronic intermittent hypoxia-induced injury.
Lymphoma, B-Cell
Cadmium Activates Reactive Oxygen Species-dependent AKT/mTOR and Mitochondrial Apoptotic Pathways in Neuronal Cells.
Lymphoma, B-Cell
Caffeine May Abrogate LPS-Induced Oxidative Stress and Neuroinflammation by Regulating Nrf2/TLR4 in Adult Mouse Brains.
Lymphoma, B-Cell
Calcium gluconate alleviates the toxic effect of hydrofluoric acid on human dermal fibroblasts through the Wnt/?-catenin pathway.
Lymphoma, B-Cell
Calf Spleen Extractive Injection (CSEI), a small peptides enriched extraction, induces human hepatocellular carcinoma cell apoptosis via ROS/MAPKs dependent mitochondrial pathway.
Lymphoma, B-Cell
Candidone Inhibits Migration and Invasion, and Induces Apoptosis in HepG2 Cells.
Lymphoma, B-Cell
Cannabinoid receptor agonist WIN55,212-2 and fatty acid amide hydrolase inhibitor URB597 suppress chronic cerebral hypoperfusion-induced neuronal apoptosis by inhibiting c-Jun N-terminal kinase signaling.
Lymphoma, B-Cell
Carbon monoxide releasing molecule-2 suppresses proliferation, migration, invasion, and promotes apoptosis in non-small cell lung cancer Calu-3 cells.
Lymphoma, B-Cell
Caspase-dependent mitochondrial apoptotic pathway is involved in astilbin-mediated cytotoxicity in breast carcinoma cells.
Lymphoma, B-Cell
Cedrus deodara (bark) essential oil induces apoptosis in human colon cancer cells by inhibiting Nuclear Factor kappa B.
Lymphoma, B-Cell
Celastrol induces the apoptosis of breast cancer cells and inhibits their invasion via downregulation of MMP-9.
Lymphoma, B-Cell
Characterization and anti-tumor activity of saponin-rich fractions of South Korean sea cucumbers (Apostichopus japonicus).
Lymphoma, B-Cell
Characterization and screening of anti-tumor activity of fucoidan from acid-processed hijiki (Hizikia fusiforme).
Lymphoma, B-Cell
Characterization of Apoptosis in a Breast Cancer Cell Line after IL-10 Silencing
Lymphoma, B-Cell
Chelerythrine chloride induces apoptosis in renal cancer HEK-293 and SW-839 cell lines.
Lymphoma, B-Cell
Chemopreventive effects of zinc on prostate carcinogenesis induced by N-methyl-N-nitrosourea and testosterone in adult male Sprague-Dawley rats.
Lymphoma, B-Cell
Chidamide, a histone deacetylase inhibitor, functions as a tumor inhibitor by modulating the ratio of Bax/Bcl-2 and P21 in pancreatic cancer.
Lymphoma, B-Cell
Chlorpyrifos induced oxidative stress to promote apoptosis and autophagy through the regulation of miR-19a-AMPK axis in common carp.
Lymphoma, B-Cell
Chronic Akt activation attenuated lipopolysaccharide-induced cardiac dysfunction via Akt/GSK3?-dependent inhibition of apoptosis and ER stress.
Lymphoma, B-Cell
Cicadidae Periostracum, the Cast-Off Skin of Cicada, Protects Dopaminergic Neurons in a Model of Parkinson's Disease.
Lymphoma, B-Cell
Circular RNA Circ_ANKMY2 Regulates Temporal Lobe Epilepsy Progression via the miR-106b-5p/FOXP1 Axis.
Lymphoma, B-Cell
Clinical case report of patients with osteosarcoma and anticancer benefit of calycosin against human osteosarcoma cells.
Lymphoma, B-Cell
Cluster of differentiation 147 (CD147) expression is linked with thiram induced chondrocyte's apoptosis via Bcl-2/Bax/Caspase-3 signalling in tibial growth plate under chlorogenic acid repercussion.
Lymphoma, B-Cell
Coenzyme Q10 protects neural stem cells against hypoxia by enhancing survival signals.
Lymphoma, B-Cell
Coix lacryma-jobi var. ma-yuen Stapf sprout extract induces cell cycle arrest and apoptosis in human cervical carcinoma cells.
Lymphoma, B-Cell
Comparisons of cardioprotective efficacy between fibroblast growth factor 21 and dipeptidyl peptidase-4 inhibitor in prediabetic rats.
Lymphoma, B-Cell
Cordycepin, a Natural Antineoplastic Agent, Induces Apoptosis of Breast Cancer Cells via Caspase-dependent Pathways.
Lymphoma, B-Cell
Could Cisplatin Loading on Biosynthesized Silver Nanoparticles Improve Its Therapeutic Efficacy on Human Prostate Cancer Cell Line and Reduce Its In Vivo Nephrotoxic Effects?
Lymphoma, B-Cell
CpG Oligodeoxynucleotides Induces Apoptosis of Human Bladder Cancer Cells via Caspase-3-Bax/Bcl-2-p53 Axis.
Lymphoma, B-Cell
Cripto Enhances Proliferation and Survival of Mesenchymal Stem Cells by Up-Regulating JAK2/STAT3 Pathway in a GRP78-Dependent Manner.
Lymphoma, B-Cell
Critical Impact of Human Amniotic Membrane Tension on Mitochondrial Function and Cell Viability In Vitro.
Lymphoma, B-Cell
Critical role of tristetraprolin and AU-rich element RNA-binding protein 1 in the suppression of cancer cell growth by globular adiponectin.
Lymphoma, B-Cell
Curcumin ameliorates streptozotocin-induced liver damage through modulation of endoplasmic reticulum stress-mediated apoptosis in diabetic rats.
Lymphoma, B-Cell
Curcumin enhances temsirolimus-induced apoptosis in human renal carcinoma cells through upregulation of YAP/p53.
Lymphoma, B-Cell
Curcumin inhibits proliferation and promotes apoptosis of breast cancer cells.
Lymphoma, B-Cell
Cycling hypoxia induces chemoresistance through the activation of reactive oxygen species-mediated B-cell lymphoma extra-long pathway in glioblastoma multiforme.
Lymphoma, B-Cell
Cytokeratin and protein expression patterns in squamous cell carcinoma of the oral cavity provide evidence for two distinct pathogenetic pathways.
Lymphoma, B-Cell
Daucosterol linolenate from Sweet Potato Suppresses MCF7-Xenograft-Tumor Growth through Regulating PI3K/AKT Pathway.
Lymphoma, B-Cell
DCA can improve the ACI-induced neurological impairment through negative regulation of Nrf2 signaling pathway.
Lymphoma, B-Cell
Deacetylated Sp1 improves ?-glycerophosphate-induced calcification in vascular smooth muscle cells.
Lymphoma, B-Cell
Demethylation of miR-34a upregulates expression of membrane palmitoylated proteins and promotes the apoptosis of liver cancer cells.
Lymphoma, B-Cell
Dexamethasone reduces brain cell apoptosis and inhibits inflammatory response in rats with intracerebral hemorrhage.
Lymphoma, B-Cell
Dexmedetomidine pretreatment protects the heart against apoptosis in ischemia/reperfusion injury in diabetic rats by activating PI3K/Akt signaling in vivo and in vitro.
Lymphoma, B-Cell
Dietary supplementation with free methionine or methionine dipeptide improves environment intestinal of broilers challenged with Eimeria spp.
Lymphoma, B-Cell
Dietary vitamin C deficiency depressed the gill physical barriers and immune barriers referring to Nrf2, apoptosis, MLCK, NF-?B and TOR signaling in grass carp (Ctenopharyngodon idella) under infection of Flavobacterium columnare.
Lymphoma, B-Cell
Dietary vitamin C deficiency depresses the growth, head kidney and spleen immunity and structural integrity by regulating NF-?B, TOR, Nrf2, apoptosis and MLCK signaling in young grass carp (Ctenopharyngodon idella).
Lymphoma, B-Cell
Different radiosensitivity of CD4(+)CD25(+) regulatory T cells and effector T cells to low dose gamma irradiation in vitro.
Lymphoma, B-Cell
Diphenyleneiodonium chloride synergizes with diazoxide to enhance protection against amyloid ? induced neurotoxicity.
Lymphoma, B-Cell
Distinctive hippocampal zinc distribution patterns following stress exposure in an animal model of PTSD.
Lymphoma, B-Cell
Docosahexaenoic acid enhances arsenic trioxide-mediated apoptosis in arsenic trioxide-resistant HL-60 cells.
Lymphoma, B-Cell
Down Syndrome Critical Region 1 Reduces Oxidative Stress-Induced Retinal Ganglion Cells Apoptosis via CREB-Bcl-2 Pathway.
Lymphoma, B-Cell
Down-expression of poly(ADP-ribose) polymerase in p53-regulated pancreatic cancer cells.
Lymphoma, B-Cell
Downregulation of YAP inhibits proliferation and induces apoptosis in Eca-109 cells.
Lymphoma, B-Cell
Duhuo Jisheng decoction treatment inhibits the sodium nitroprussiate?induced apoptosis of chondrocytes through the mitochondrial?dependent signaling pathway.
Lymphoma, B-Cell
Duration of brain death and cold ischemia time, but not warm ischemia time, increases expression of genes associated with apoptosis in transplanted kidneys from deceased donors.
Lymphoma, B-Cell
Dysregulated Hepatic Methionine Metabolism Drives Homocysteine Elevation in Diet-Induced Nonalcoholic Fatty Liver Disease.
Lymphoma, B-Cell
Effect of beclin 1 expression on the biological behavior and chemotherapy sensitivity of cervical cancer cells.
Lymphoma, B-Cell
Effect of cell cycle phase on the sensitivity of SAS cells to sonodynamic therapy using low-intensity ultrasound combined with 5-aminolevulinic acid in vitro.
Lymphoma, B-Cell
Effect of Gastrodin on Early Brain Injury and Neurological Outcome After Subarachnoid Hemorrhage in Rats.
Lymphoma, B-Cell
Effect of Ginkgo biloba extract on apoptosis of brain tissues in rats with acute cerebral infarction and related gene expression.
Lymphoma, B-Cell
Effect of levocarnitine on cerebral ischemia-reperfusion rats via activating Nrf2/ARE signaling pathway.
Lymphoma, B-Cell
Effect of limb ischemic preconditioning on myocardial apoptosis-related proteins in ischemia-reperfusion injury.
Lymphoma, B-Cell
Effect of metformin and sitagliptin on doxorubicin-induced cardiotoxicity in adult male albino rats.
Lymphoma, B-Cell
Effect of miR-140-5p on the regulation of proliferation and apoptosis in NSCLC and its underlying mechanism.
Lymphoma, B-Cell
Effect of miR-155 knockdown on the reversal of doxorubicin resistance in human lung cancer A549/dox cells.
Lymphoma, B-Cell
Effect of miR-21/TLR4/NF-?B pathway on myocardial apoptosis in rats with myocardial ischemia-reperfusion.
Lymphoma, B-Cell
Effect of Paris saponin I on radiosensitivity in a gefitinib-resistant lung adenocarcinoma cell line.
Lymphoma, B-Cell
Effect of phosphodiesterase-5 inhibition on apoptosis and beta amyloid load in aged mice.
Lymphoma, B-Cell
Effect of selective inhibition of aquaporin 1 on chemotherapy sensitivity of J82 human bladder cancer cells.
Lymphoma, B-Cell
Effects of aspirin on proliferation, invasion and apoptosis of Hep-2 cells via the PTEN/AKT/NF-?B/survivin signaling pathway.
Lymphoma, B-Cell
Effects of capsaicin on adipogenic differentiation in bovine bone marrow mesenchymal stem cell.
Lymphoma, B-Cell
Effects of dietary monocalcium phosphate supplementation on the anti-oxidative capacity, anti-bacteria function in immune organs of obscure puffer (Takifugu obscurus) after infection with Aeromonas hydrophila.
Lymphoma, B-Cell
Effects of ELL-associated factor 2 on ultraviolet radiation-induced cataract formation in mice.
Lymphoma, B-Cell
Effects of ellagic acid on chemosensitivity to 5-fluorouracil in colorectal carcinoma cells.
Lymphoma, B-Cell
Effects of microRNA-1271 on ovarian cancer via inhibition of epithelial-mesenchymal transition and cisplatin resistance.
Lymphoma, B-Cell
Effects of microRNA-21 and microRNA-24 inhibitors on neuronal apoptosis in ischemic stroke.
Lymphoma, B-Cell
Effects of NOB1 on the pathogenesis of osteosarcoma and its expression on the chemosensitivity to cisplatin.
Lymphoma, B-Cell
Effects of Postconditioning on Skeletal Muscle Injury and Apoptosis Induced by Partial Ischemia and Reperfusion in Rats.
Lymphoma, B-Cell
Effects of progesterone receptor on proliferation of uterine leiomyoma cells.
Lymphoma, B-Cell
Effects of the root bark of Paeonia suffruticosa on mitochondria-mediated neuroprotection in an MPTP-induced model of Parkinson's disease.
Lymphoma, B-Cell
Efficacy of Zhonglun'a-decoction-containing serum on fibroblast-like synoviocyte apoptosis in rats with collagen-induced arthritis via inhibiting Janus kinase/signal transducer and activator of transcription signaling pathway.
Lymphoma, B-Cell
Endoplasmic Reticulum Stress and Neurodegeneration in Experimental Cerebral Malaria.
Lymphoma, B-Cell
Enhanced Susceptibility to 5-Fluorouracil in Human Colon Cancer Cells by Silencing of GRP78.
Lymphoma, B-Cell
Epac is required for GLP-1R-mediated inhibition of oxidative stress and apoptosis in cardiomyocytes.
Lymphoma, B-Cell
Epigallocatechin-3-gallate protects against hepatic ischaemia-reperfusion injury by reducing oxidative stress and apoptotic cell death.
Lymphoma, B-Cell
ERKs and mitochondria-related pathways are essential for glycyrrhizic acid-mediated neuroprotection against glutamate-induced toxicity in differentiated PC12 cells.
Lymphoma, B-Cell
Ethanol extract of Ligustrum lucidum Ait. leaves suppressed hepatocellular carcinoma in vitro and in vivo.
Lymphoma, B-Cell
Eugenol Exerts Apoptotic Effect and Modulates the Sensitivity of HeLa Cells to Cisplatin and Radiation.
Lymphoma, B-Cell
Eugenol protects the transplanted heart against ischemia/reperfusion injury in rats by inhibiting the inflammatory response and apoptosis.
Lymphoma, B-Cell
Evaluation of the renoprotective effect of nano turmeric against toxic dose of copper sulfate: Role of vascular cell adhesion molecule-1, kidney injury molecule-1, and signal transducer and activator of transcription 3 protein expressions.
Lymphoma, B-Cell
Evidence of altered depression and dementia-related proteins in the brains of young rats after ovariectomy.
Lymphoma, B-Cell
Exogenous vascular endothelial growth factor delivery prior to endothelial precursor cell transplantation in orthotopic liver transplantation-induced hepatic ischemia/reperfusion injury.
Lymphoma, B-Cell
Exosomes derived from bone marrow stromal cells decrease the sensitivity of leukemic cells to etoposide.
Lymphoma, B-Cell
Exosomes derived from human platelet-rich plasma prevent apoptosis induced by glucocorticoid-associated endoplasmic reticulum stress in rat osteonecrosis of the femoral head via the Akt/Bad/Bcl-2 signal pathway.
Lymphoma, B-Cell
Exposure of isoflurane-treated cells to hyperoxia decreases cell viability and activates the mitochondrial apoptotic pathway.
Lymphoma, B-Cell
Expression of minichromosome maintenance 8 in chronic myelogenous leukemia.
Lymphoma, B-Cell
Expression of SIRT1 and apoptosis-related proteins is predictive for lymph node metastasis and disease-free survival in luminal A breast cancer.
Lymphoma, B-Cell
Extracellular Vesicles Derived from Wharton's Jelly Mesenchymal Stem Cells Prevent and Resolve Programmed Cell Death Mediated by Perinatal Hypoxia-Ischemia in Neuronal Cells.
Lymphoma, B-Cell
Fangchinoline Promotes Autophagy and Inhibits Apoptosis in Osteoporotic Rats.
Lymphoma, B-Cell
Ferulic acid protects lymphocytes from radiation-predisposed oxidative stress through extracellular regulated kinase.
Lymphoma, B-Cell
Fibroblast growth factor receptor 4 regulates proliferation and antiapoptosis during gastric cancer progression.
Lymphoma, B-Cell
Fisetin alleviates oxidative stress after traumatic brain injury via the Nrf2-ARE pathway.
Lymphoma, B-Cell
Flavonoid Naringenin Attenuates Oxidative Stress, Apoptosis and Improves Neurotrophic Effects in the Diabetic Rat Retina.
Lymphoma, B-Cell
Flavonoids isolated from Citrus platymamma induced G2/M cell cycle arrest and apoptosis in A549 human lung cancer cells.
Lymphoma, B-Cell
Fmr1 protects cardiomyocytes against lipopolysaccharide-induced myocardial injury.
Lymphoma, B-Cell
Follicle-stimulating hormone-induced rescue of cumulus cell apoptosis and enhanced development ability of buffalo oocytes.
Lymphoma, B-Cell
Functions of microRNA-143 in the apoptosis, invasion and migration of nasopharyngeal carcinoma.
Lymphoma, B-Cell
Gastrodin Alleviates Cerebral Ischemic Damage in Mice by Improving Anti-oxidant and Anti-inflammation Activities and Inhibiting Apoptosis Pathway.
Lymphoma, B-Cell
GATA1/SP1 and miR-874 mediate enterovirus-71-induced apoptosis in a granzyme-B-dependent manner in Jurkat cells.
Lymphoma, B-Cell
Ghrelin inhibits cisplatin-induced MDA-MB-231 breast cancer cell apoptosis via PI3K/Akt/mTOR signaling.
Lymphoma, B-Cell
Ginkgo biloba Extract EGb761 Attenuates Bleomycin-Induced Experimental Pulmonary Fibrosis in Mice by Regulating the Balance of M1/M2 Macrophages and Nuclear Factor Kappa B (NF-?B)-Mediated Cellular Apoptosis.
Lymphoma, B-Cell
Ginsenoside Rd as a potential neuroprotective agent prevents trimethyltin injury.
Lymphoma, B-Cell
Ginsenoside Rg1 relieves tert-Butyl hydroperoxide-induced cell impairment in mouse microglial BV2 cells.
Lymphoma, B-Cell
Grape seeds and skin induce tumor growth inhibition via G1-phase arrest and apoptosis in mice inoculated with Ehrlich ascites carcinoma.
Lymphoma, B-Cell
Graviola mitigates acetic acid-induced ulcerative colitis in rats: insight on apoptosis and Wnt/Hh signaling crosstalk.
Lymphoma, B-Cell
Green tea and its active compound epigallocathechin-3-gallate (EGCG) inhibit neuronal apoptosis in a middle cerebral artery occlusion (MCAO) model.
Lymphoma, B-Cell
Gui-A-Gra Attenuates Testicular Dysfunction in Varicocele-Induced Rats via Oxidative Stress, ER Stress and Mitochondrial Apoptosis Pathway.
Lymphoma, B-Cell
Hazelnut and neuroprotection: Improved memory and hindered anxiety in response to intra-hippocampal A? injection.
Lymphoma, B-Cell
Heme oxygenase-1 exerts pro-apoptotic effects on hepatic stellate cells in vitro through regulation of nuclear factor-?B.
Lymphoma, B-Cell
Hesperetin induces apoptosis of esophageal cancer cells via mitochondrial pathway mediated by the increased intracellular reactive oxygen species.
Lymphoma, B-Cell
Hesperetin Promotes Cisplatin-Induced Apoptosis of Gastric Cancer In Vitro and In Vivo by Upregulating PTEN Expression.
Lymphoma, B-Cell
Hesperetin, a Citrus Flavonoid, Attenuates LPS-Induced Neuroinflammation, Apoptosis and Memory Impairments by Modulating TLR4/NF-?B Signaling.
Lymphoma, B-Cell
Hesperidin Attenuates Ultraviolet B-Induced Apoptosis by Mitigating Oxidative Stress in Human Keratinocytes.
Lymphoma, B-Cell
HIF-?/PKM2 and PI3K-AKT pathways involved in the protection by dexmedetomidine against isoflurane or bupivacaine-induced apoptosis in hippocampal neuronal HT22 cells.
Lymphoma, B-Cell
Hsp27 (HSPB1) differential expression in normal salivary glands and pleomorphic adenomas and association with an increased Bcl2/Bax ratio.
Lymphoma, B-Cell
HSP70/HSP90-Organizing Protein Contributes to Gastric Cancer Progression in an Autocrine Fashion and Predicts Poor Survival in Gastric Cancer.
Lymphoma, B-Cell
Huaier aqueous extract induces apoptosis of human fibrosarcoma HT1080 cells through the mitochondrial pathway.
Lymphoma, B-Cell
Human bocavirus induces apoptosis and autophagy in human bronchial epithelial cells.
Lymphoma, B-Cell
Hyperoside Attenuates Hepatic Ischemia-Reperfusion Injury by Suppressing Oxidative Stress and Inhibiting Apoptosis in Rats.
Lymphoma, B-Cell
Hyperthermia enhances the sensitivity of pancreatic cancer SW1990 cells to gemcitabine through ROS/JNK signaling.
Lymphoma, B-Cell
Hypoglycemic Effect of Acidic Polysaccharide from Schisandra chinensis on T2D Rats Induced by High-Fat Diet Combined with STZ.
Lymphoma, B-Cell
Ibuprofen abates cypermethrin-induced expression of pro-inflammatory mediators and mitogen-activated protein kinases and averts the nigrostriatal dopaminergic neurodegeneration.
Lymphoma, B-Cell
Ibuprofen Protects from Cypermethrin-Induced Changes in the Striatal Dendritic Length and Spine Density.
Lymphoma, B-Cell
Immunohistochemical analysis of cleaved caspase-3 detects high level of apoptosis frequently in diffuse large B-cell lymphomas of the central nervous system.
Lymphoma, B-Cell
Immunolocalization of the ICE/Ced-3-family protease, CPP32 (Caspase-3), in non-Hodgkin's lymphomas, chronic lymphocytic leukemias, and reactive lymph nodes.
Lymphoma, B-Cell
Induction of apoptosis in HCT-116 colon cancer cells by polysaccharide of Larimichthys crocea swim bladder.
Lymphoma, B-Cell
Induction of apoptosis in human leukemia cells through an intrinsic pathway by cathachunine, a unique alkaloid isolated from Catharanthus roseus.
Lymphoma, B-Cell
Inflammation, oxidative stress and apoptosis cascade implications in bisphenol A-induced liver fibrosis in male rats.
Lymphoma, B-Cell
Influence of Delphinidin-3-glucoside on Oxidized Low-Density Lipoprotein-Induced Oxidative Stress and Apoptosis in Cultured Endothelial Cells.
Lymphoma, B-Cell
Influences of cold atmospheric plasma on apoptosis related molecules in osteoblast-like cells in vitro.
Lymphoma, B-Cell
Inhibition of 5-lipoxygenase represses neutrophils activation and activates apoptosis in pancreatic tissues during acute necrotizing pancreatitis.
Lymphoma, B-Cell
Inhibition of cell proliferation by mild hyperthermia at 43?C with Paris Saponin I in the lung adenocarcinoma cell line PC-9.
Lymphoma, B-Cell
Inhibition of chemotherapy-induced apoptosis of testicular cells by squid ink polysaccharide.
Lymphoma, B-Cell
Inhibition of miR-153 ameliorates ischemia/reperfusion-induced cardiomyocytes apoptosis by regulating Nrf2/HO-1 signaling in rats.
Lymphoma, B-Cell
Inhibition of Proliferation in U937 Cells Treated by Blue Light Irradiation and Combined Blue Light Irradiation/Drug.
Lymphoma, B-Cell
Interleukin-24 inhibits influenza A virus replication in vitro through induction of toll-like receptor 3 dependent apoptosis.
Lymphoma, B-Cell
Inulin Induces Dendritic Cells Apoptosis through the Caspase-Dependent Pathway and Mitochondrial Dysfunction.
Lymphoma, B-Cell
Investigation of the anti-cataractogenic mechanisms of curcumin through in vivo and in vitro studies.
Lymphoma, B-Cell
Involvement of de novo ceramide synthesis in radiocontrast-induced renal tubular cell injury.
Lymphoma, B-Cell
Irbesartan mitigates acute liver injury, oxidative stress, and apoptosis induced by acetaminophen in mice.
Lymphoma, B-Cell
Ischemic Preconditioning Produces Comparable Protection Against Hepatic Ischemia/Reperfusion Injury Under Isoflurane and Sevoflurane Anesthesia in Rats.
Lymphoma, B-Cell
Isolinderalactone regulates the BCL-2/caspase-3/PARP pathway and suppresses tumor growth in a human glioblastoma multiforme xenograft mouse model.
Lymphoma, B-Cell
Jinmaitong decreases sciatic nerve DNA oxidative damage and apoptosis in a streptozotocin-induced diabetic rat model.
Lymphoma, B-Cell
JTC-801 inhibits the proliferation and metastasis of the Hep G2 hepatoblastoma cell line by regulating the phosphatidylinositol 3-kinase/protein kinase B signalling pathway.
Lymphoma, B-Cell
Kalopanacis Cortex extract-capped gold nanoparticles activate NRF2 signaling and ameliorate damage in human neuronal SH-SY5Y cells exposed to oxygen-glucose deprivation and reoxygenation.
Lymphoma, B-Cell
Knockdown of lncRNA-HOTAIR downregulates the drug-resistance of breast cancer cells to doxorubicin via the PI3K/AKT/mTOR signaling pathway.
Lymphoma, B-Cell
Knockdown of long noncoding RNA XIST mitigates the apoptosis and inflammatory injury of microglia cells after spinal cord injury through miR-27a/Smurf1 axis.
Lymphoma, B-Cell
Korean Red Ginseng Extract Enhances the Anticancer Effects of Sorafenib through Abrogation of CREB and c-Jun Activation in Renal Cell Carcinoma.
Lymphoma, B-Cell
Krüppel-like factor 7 attenuates hippocampal neuronal injury after traumatic brain injury.
Lymphoma, B-Cell
Lactobacillus acidophilus-Fermented Germinated Brown Rice Suppresses Preneoplastic Lesions of the Colon in Rats.
Lymphoma, B-Cell
LDR reverses DDP resistance in ovarian cancer cells by affecting ERCC-1, Bcl-2, Survivin and Caspase-3 expressions.
Lymphoma, B-Cell
Lentivirus-induced knockdown of LRP1 induces osteoarthritic-like effects and increases susceptibility to apoptosis in chondrocytes via the nuclear factor-?B pathway.
Lymphoma, B-Cell
Lentivirus-mediated silencing of HOTAIR lncRNA restores gefitinib sensitivity by activating Bax/Caspase-3 and suppressing TGF-?/EGFR signaling in lung adenocarcinoma.
Lymphoma, B-Cell
Ligustrazine suppresses neuron apoptosis via the Bax/Bcl-2 and caspase-3 pathway in PC12 cells and in rats with vascular dementia.
Lymphoma, B-Cell
Lipoapoptosis Pathways in Pancreatic ?-Cells and the Anti-Apoptosis Mechanisms of Adiponectin.
Lymphoma, B-Cell
LncRNA THUMPD3-AS1 enhances the proliferation and inflammatory response of chondrocytes in osteoarthritis.
Lymphoma, B-Cell
LncRNA-LINC01089 inhibits lung adenocarcinoma cell proliferation and promotes apoptosis via sponging miR-543.
Lymphoma, B-Cell
Long non-coding RNA H19 knockdown inhibits the cell viability and promotes apoptosis of thyroid cancer cells through regulating the PI3K/AKT pathway.
Lymphoma, B-Cell
Long Non-coding RNA MALAT1 Alleviates the Elevated Intraocular Pressure (Eiop)-induced Glaucoma Progression via Sponging miR-149-5p.
Lymphoma, B-Cell
Long non-coding RNA nuclear paraspeckle assembly transcript 1 protects human lens epithelial cells against H2O2 stimuli through the nuclear factor kappa b/p65 and p38/mitogen-activated protein kinase axis.
Lymphoma, B-Cell
Loss of RIPK3 and Caspase-8 Augments Intrinsic Apoptosis in Tubular Epithelial Cell and promote Kidney Ischemia Reperfusion Injury.
Lymphoma, B-Cell
Low temperature exerts protective effects by inhibiting mitochondria-mediated apoptosis pathway following pressure injury to rat muscle.
Lymphoma, B-Cell
Luteolin induces apoptosis in vitro through suppressing the MAPK and PI3K signaling pathways in gastric cancer.
Lymphoma, B-Cell
Lycopene attenuates aluminum-induced hippocampal lesions by inhibiting oxidative stress-mediated inflammation and apoptosis in the rat.
Lymphoma, B-Cell
M1 macrophage-derived exosome-encapsulated cisplatin can enhance its anti-lung cancer effect.
Lymphoma, B-Cell
Magnesium Isoglycyrrhizinate Alleviates Arsenic Trioxide-Induced Cardiotoxicity: Contribution of Nrf2 and TLR4/NF-?B Signaling Pathway.
Lymphoma, B-Cell
MALAT1 inhibits the Wnt/?-catenin signaling pathway in colon cancer cells and affects cell proliferation and apoptosis.
Lymphoma, B-Cell
Matrix metalloproteinase 9 and transglutaminase 2 expression at the ocular surface in patients with different forms of dry eye disease.
Lymphoma, B-Cell
Melatonin Attenuates AlCl3-Induced Apoptosis and Osteoblastic Differentiation Suppression by Inhibiting Oxidative Stress in MC3T3-E1 Cells.
Lymphoma, B-Cell
Melatonin attenuates cisplatin-induced acute kidney injury in rats via induction of anti-aging protein, Klotho.
Lymphoma, B-Cell
Melatonin Improves Endoplasmic Reticulum Stress-Mediated IRE1? Pathway in Zücker Diabetic Fatty Rat.
Lymphoma, B-Cell
Melatonin protects against chromium(VI)-induced cardiac injury via activating the AMPK/Nrf2 pathway.
Lymphoma, B-Cell
Melatonin reverses flow shear stress-induced injury in bone marrow mesenchymal stem cells via activation of AMP-activated protein kinase signaling.
Lymphoma, B-Cell
Mesencephalic astrocyte-derived neurotrophic factor affords neuroprotection to early brain injury induced by subarachnoid hemorrhage via activating Akt-dependent prosurvival pathway and defending blood-brain barrier integrity.
Lymphoma, B-Cell
Metformin in combination with cisplatin inhibits cell viability and induces apoptosis of human ovarian cancer cells by inactivating ERK 1/2.
Lymphoma, B-Cell
Metformin reduces pancreatic cancer cell proliferation and increases apoptosis through MTOR signaling pathway and its dose-effect relationship.
Lymphoma, B-Cell
Methane supplementation improves graft function in experimental heart transplantation.
Lymphoma, B-Cell
Methyl Sartortuoate Inhibits Colon Cancer Cell Growth by Inducing Apoptosis and G2/M-Phase Arrest.
Lymphoma, B-Cell
Methylene Blue Exerts Anticonvulsant and Neuroprotective Effects on Self-Sustaining Status Epilepticus (SSSE) Induced by Prolonged Basolateral Amygdala Stimulation in Wistar Rats.
Lymphoma, B-Cell
MicroRNA 21 targets BCL2 mRNA to increase apoptosis in rat and human beta cells.
Lymphoma, B-Cell
MicroRNA-10a suppresses breast cancer progression via PI3K/Akt/mTOR pathway.
Lymphoma, B-Cell
MicroRNA-140 inhibits skeletal muscle glycolysis and atrophy in endotoxin-induced sepsis in mice via the WNT signaling pathway.
Lymphoma, B-Cell
MicroRNA-142 protects MC3T3-E1 cells against high glucose-induced apoptosis by targeting ?-catenin.
Lymphoma, B-Cell
MicroRNA-153 affects nasopharyngeal cancer cell viability by targeting TGF-?2.
Lymphoma, B-Cell
microRNA-22 attenuates neuronal cell apoptosis in a cell model of traumatic brain injury.
Lymphoma, B-Cell
MicroRNA-29b promotes cell sensitivity to Temozolomide by targeting STAT3 in glioma.
Lymphoma, B-Cell
MicroRNA-488 inhibits neural inflammation and apoptosis in spinal cord injury through restraint on the HMGB1/TLR4/NF-?B signaling pathway.
Lymphoma, B-Cell
MicroRNA-744 promotes cell apoptosis via targeting B cell lymphoma-2 in gastric cancer cell line SGC-7901.
Lymphoma, B-Cell
MiR-145-5p promotes myocardial cell apoptosis in rats with myocardial infarction through PI3K/Akt signaling pathway.
Lymphoma, B-Cell
MiR-200c regulates apoptosis of placental trophoblasts in preeclampsia rats through Wnt/?-catenin signaling pathway.
Lymphoma, B-Cell
MiR-20a lowers chemosensitivity of liver cancer Huh-7 cells via regulating NF-?B expression.
Lymphoma, B-Cell
MiR-20b promotes osteocyte apoptosis in rats with steroid-induced necrosis of the femoral head through BMP signaling pathway.
Lymphoma, B-Cell
MiR-21 regulates pulmonary hypertension in rats via TGF-?1/Smad2 signaling pathway.
Lymphoma, B-Cell
miR-210-3p regulates the proliferation and apoptosis of non-small cell lung cancer cells by targeting SIN3A.
Lymphoma, B-Cell
miR-30d inhibits cell biological progression of Ewing's sarcoma by suppressing the MEK/ERK and PI3K/Akt pathways
Lymphoma, B-Cell
miR-340 Inhibits Proliferation and Induces Apoptosis in Gastric Cancer Cell Line SGC-7901, Possibly via the AKT Pathway.
Lymphoma, B-Cell
miR-378a-5p and miR-630 induce lens epithelial cell apoptosis in cataract via suppression of E2F3.
Lymphoma, B-Cell
MiR-499a suppresses LPS-induced human vascular endothelial cell inflammatory response and apoptosis by regulating STAT1.
Lymphoma, B-Cell
Mitochondrial separation protein inhibitor inhibits cell apoptosis in rat lungs during intermittent hypoxia.
Lymphoma, B-Cell
MMP-1 is overexpressed in triple-negative breast cancer tissues and the knockdown of MMP-1 expression inhibits tumor cell malignant behaviors in vitro.
Lymphoma, B-Cell
Modulation of the DNA repair system and ATR-p53 mediated apoptosis is relevant for tributyltin-induced genotoxic effects in human hepatoma G2 cells.
Lymphoma, B-Cell
Mori Fructus improves cognitive and neuronal dysfunction induced by beta-amyloid toxicity through the GSK-3? pathway in vitro and in vivo.
Lymphoma, B-Cell
Morroniside protects against cerebral ischemia/reperfusion injury by inhibiting neuron apoptosis and MMP2/9 expression.
Lymphoma, B-Cell
MOTILIPERM Ameliorates Immobilization Stress-Induced Testicular Dysfunction via Inhibition of Oxidative Stress and Modulation of the Nrf2/HO-1 Pathway in SD Rats.
Lymphoma, B-Cell
mTOR inhibition as a possible pharmacological target in the management of systemic inflammatory response and associated neuroinflammation by lipopolysaccharide challenge in rats.
Lymphoma, B-Cell
Multiple effects of Xihuang pill aqueous extract on the Hs578T triple-negative breast cancer cell line.
Lymphoma, B-Cell
Nanocurcumin versus mesenchymal stem cells in ameliorating the deleterious effects in the cadmium-induced testicular injury: A crosstalk between oxidative and apoptotic markers.
Lymphoma, B-Cell
Nanofluidic proteomic assay for serial analysis of oncoprotein activation in clinical specimens.
Lymphoma, B-Cell
Naringin inhibits ovarian tumor growth by promoting apoptosis: An in vivo study.
Lymphoma, B-Cell
Native macrophages genetically modified to express heme oxygenase 1 protect rat liver transplants from ischemia/reperfusion injury.
Lymphoma, B-Cell
Nerve Protective Effect of Asiaticoside against Ischemia-Hypoxia in Cultured Rat Cortex Neurons.
Lymphoma, B-Cell
Neuroprotective and antioxidant activities of bamboo salt soy sauce against H2O2-induced oxidative stress in rat cortical neurons.
Lymphoma, B-Cell
Neuroprotective capabilities of Tanshinone IIA against cerebral ischemia/reperfusion injury via anti-apoptotic pathway in rats.
Lymphoma, B-Cell
Neuroprotective effect of Citrus unshiu immature peel and nobiletin inhibiting hydrogen peroxide-induced oxidative stress in HT22 murine hippocampal neuronal cells.
Lymphoma, B-Cell
Neuroprotective effect of hyperbaric oxygen therapy on anterior ischemic optic neuropathy.
Lymphoma, B-Cell
Neuroprotective effect of paeoniflorin on H2O2-induced apoptosis in PC12 cells by modulation of reactive oxygen species and the inflammatory response.
Lymphoma, B-Cell
Neuroprotective Effects of 17?-Estradiol against Thrombin-Induced Apoptosis in Primary Cultured Cortical Neurons.
Lymphoma, B-Cell
Neuroprotective effects of astaxanthin against oxygen and glucose deprivation damage via the PI3K/Akt/GSK3?/Nrf2 signalling pathway in vitro.
Lymphoma, B-Cell
Neuroprotective effects of Rhizoma Dioscoreae polysaccharides against neuronal apoptosis induced by in vitro hypoxia.
Lymphoma, B-Cell
Neuroprotective role of an N-acetyl serotonin derivative via activation of tropomyosin-related kinase receptor B after subarachnoid hemorrhage in a rat model.
Lymphoma, B-Cell
No donor KMUP-1 improves hepatic ischemia-reperfusion and hypoxic cell injury by inhibiting oxidative stress and pro-inflammatory signaling.
Lymphoma, B-Cell
Norcantharidin Inhibits SK-N-SH Neuroblastoma Cell Growth by Induction of Autophagy and Apoptosis.
Lymphoma, B-Cell
Novel Insights on the Corpus Luteum Function: Role of Vaspin on Porcine Luteal Cell Angiogenesis, Proliferation and Apoptosis by Activation of GRP78 Receptor and MAP3/1 Kinase Pathways.
Lymphoma, B-Cell
Novel sulphonamide benzoquinazolinones as dual EGFR/HER2 inhibitors, apoptosis inducers and radiosensitizers.
Lymphoma, B-Cell
OMP31 of Brucella melitensis 16M impairs the apoptosis of macrophages triggered by TNF-?.
Lymphoma, B-Cell
Oral treatment with herbal formula B307 alleviates cardiac failure in aging R6/2 mice with Huntington's disease via suppressing oxidative stress, inflammation, and apoptosis.
Lymphoma, B-Cell
Oral treatment with the herbal formula B307 alleviates cardiac toxicity in doxorubicin-treated mice via suppressing oxidative stress, inflammation, and apoptosis.
Lymphoma, B-Cell
Oral treatment with the herbal formula B401 protects against aging-dependent neurodegeneration by attenuating oxidative stress and apoptosis in the brain of R6/2 mice.
Lymphoma, B-Cell
Overexpression of E74-Like Factor 5 (ELF5) Inhibits Migration and Invasion of Ovarian Cancer Cells.
Lymphoma, B-Cell
Overexpression of MYCT1 Inhibits Proliferation and Induces Apoptosis in Human Acute Myeloid Leukemia HL-60 and KG-1a Cells in vitro and in vivo.
Lymphoma, B-Cell
Overexpression of Shrm4 promotes proliferation and differentiation of neural stem cells through activation of GABA signaling pathway.
Lymphoma, B-Cell
Oxidative stress on the astrocytes in culture derived from a senescence accelerated mouse strain.
Lymphoma, B-Cell
Ozone induces BEL7402 cell apoptosis by increasing reactive oxygen species production and activating JNK.
Lymphoma, B-Cell
p53?: a new prognostic marker for patients with clear-cell renal cell carcinoma from 5.3 years of median follow-up.
Lymphoma, B-Cell
Pachymic acid inhibits growth and induces cell cycle arrest and apoptosis in gastric cancer SGC-7901 cells.
Lymphoma, B-Cell
Palmitic Acid-Induced Podocyte Apoptosis via the Reactive Oxygen Species-Dependent Mitochondrial Pathway.
Lymphoma, B-Cell
Paradoxical effect of testosterone supplementation therapy on cardiac ischemia/reperfusion injury in aged rats.
Lymphoma, B-Cell
Pathophysiological amyloid concentrations induce sustained upregulation of readthrough acetylcholinesterase mediating anti-apoptotic effects.
Lymphoma, B-Cell
Peroxiredoxin 6 overexpression regulates adriamycin-induced myocardial injury, oxidative stress and immune response in rats.
Lymphoma, B-Cell
Peroxisome Proliferator-Activated Receptor-? Coactivator-1? (PGC-1?) Enhances Engraftment and Angiogenesis of Mesenchymal Stem Cells in Diabetic Hindlimb Ischemia.
Lymphoma, B-Cell
Phenethyl isothiocyanate triggers apoptosis in human malignant melanoma A375.S2 cells through reactive oxygen species and the mitochondria-dependent pathways.
Lymphoma, B-Cell
Phloretin loaded chitosan nanoparticles enhance the antioxidants and apoptotic mechanisms in DMBA induced experimental carcinogenesis.
Lymphoma, B-Cell
Photoactivation of hypericin decreases the viability of RINm5F insulinoma cells through reduction in JNK/ERK phosphorylation and elevation of caspase-9/caspase-3 cleavage and Bax-to-Bcl-2 ratio.
Lymphoma, B-Cell
Photodynamic Effects of Vitamin K3 on Cervical Carcinoma Cells Activating Mitochondrial Apoptosis Pathways.
Lymphoma, B-Cell
Photothermolysis mediated by gold nanorods modified with EGFR monoclonal antibody induces Hep-2 cells apoptosis in vitro and in vivo.
Lymphoma, B-Cell
Phyllanthin Averts Oxidative Stress and Neuroinflammation in Cerebral Ischemic-Reperfusion Injury through Modulation of the NF-?B and AMPK/Nrf2 Pathways.
Lymphoma, B-Cell
Physical and cognitive training attenuate hippocampal ischemia-induced memory impairments in rat.
Lymphoma, B-Cell
PI3K/Akt Signaling Pathway Ameliorates Oxidative Stress-Induced Apoptosis upon Manganese Exposure in PC12 Cells.
Lymphoma, B-Cell
PI3K/Akt signaling pathway and Hsp70 activate in hippocampus of rats with chronic manganese sulfate exposure.
Lymphoma, B-Cell
Pink1 attenuates propofol-induced apoptosis and oxidative stress in developing neurons.
Lymphoma, B-Cell
Pipoxolan Exhibits Antitumor Activity Toward Oral Squamous Cell Carcinoma Through Reactive Oxygen Species-mediated Apoptosis.
Lymphoma, B-Cell
Platelet-rich plasma ameliorates gamma radiation-induced nephrotoxicity via modulating oxidative stress and apoptosis.
Lymphoma, B-Cell
Polysaccharides from Enteromorpha prolifera protect against carbon tetrachloride-induced acute liver injury in mice via activation of Nrf2/HO-1 signaling, and suppression of oxidative stress, inflammation and apoptosis.
Lymphoma, B-Cell
Potential Metabolite Nymphayol Isolated from Water Lily (Nymphaea stellata) Flower Inhibits MCF-7 Human Breast Cancer Cell Growth via Upregulation of Cdkn2a, pRb2, p53 and Downregulation of PCNA mRNA Expressions.
Lymphoma, B-Cell
Preparation of catechin extracts and nanoemulsions from green tea leaf waste and their inhibition effect on prostate cancer cell PC-3.
Lymphoma, B-Cell
Pretreatment with Lycopene Attenuates Oxidative Stress-Induced Apoptosis in Human Mesenchymal Stem Cells.
Lymphoma, B-Cell
Pretreatment with the tumor nerosis factor-alpha blocker etanercept attenuated ischemia-reperfusion renal injury.
Lymphoma, B-Cell
Pro-apoptotic and anti-proliferative effects of corn silk extract on human colon cancer cell lines.
Lymphoma, B-Cell
Pro-apoptotic effects of Kangfuxin on human stomach cancer cells and its underlying mechanism.
Lymphoma, B-Cell
Procyanidin Compound (PC) Suppresses Lipopolysaccharide-Induced Cervical Cancer Cell Proliferation Through Blocking the TLR4/NF-?B Pathway.
Lymphoma, B-Cell
Prognostic Significance of Survivin and Caspase-3 Immunohistochemical Expression in Patients with Diffuse Large B-cell Lymphoma Treated with Rituximab and CHOP.
Lymphoma, B-Cell
Promising Anticancer Effect of Aurisin A Against the Human Lung Cancer A549 Cell Line.
Lymphoma, B-Cell
Propofol inhibits proliferation and induces neuroapoptosis of hippocampal neurons in vitro via downregulation of NF-?B p65 and Bcl-2 and upregulation of caspase-3.
Lymphoma, B-Cell
Protection against Ultraviolet A-Induced Skin Apoptosis and Carcinogenesis through the Oxidative Stress Reduction Effects of N-(4-bromophenethyl) Caffeamide, A Propolis Derivative.
Lymphoma, B-Cell
Protective Effect of 3,4-Dihydroxybenzoic Acid Isolated from Cladophora wrightiana Harvey Against Ultraviolet B Radiation-Induced Cell Damage in Human HaCaT Keratinocytes.
Lymphoma, B-Cell
Protective Effect of Alpha 1-Antitrypsin on Renal Ischemia-Reperfusion Injury.
Lymphoma, B-Cell
Protective effect of berberine against oxidative stress-induced apoptosis in rat bone marrow-derived mesenchymal stem cells.
Lymphoma, B-Cell
Protective effect of controlled release of cytokine response modifier A from chitosan microspheres on rat chondrocytes from interleukin-1? induced inflammation and apoptosis.
Lymphoma, B-Cell
Protective Effect of Diphenhydramine against Traumatic Brain Injury in Rats via Modulation of Oxidative Stress and Inflammation.
Lymphoma, B-Cell
Protective effect of eupatilin against renal ischemia-reperfusion injury in mice.
Lymphoma, B-Cell
Protective Effect of Eupatilin Pretreatment Against Hepatic Ischemia-Reperfusion Injury in Mice.
Lymphoma, B-Cell
Protective Effect of Hesperidin Against Sepsis-Induced Lung Injury by Inducing the Heat-Stable Protein 70 (Hsp70)/Toll-Like Receptor 4 (TLR4)/ Myeloid Differentiation Primary Response 88 (MyD88) Pathway.
Lymphoma, B-Cell
Protective effect of hypoxylonol C and 4,5,4',5'-tetrahydroxy-1,1'-binaphthyl isolated from Annulohypoxylon annulatum against streptozotocin-induced damage in INS-1 cells.
Lymphoma, B-Cell
Protective effect of vascular endothelial growth factor against cardiopulmonary bypass-associated acute kidney injury in beagles.
Lymphoma, B-Cell
Protective effect of zinc on N-methyl-N-nitrosourea and testosterone-induced prostatic intraepithelial neoplasia in the dorsolateral prostate of Sprague Dawley rats.
Lymphoma, B-Cell
Protective effects and mechanism of curcumin on myocardial injury induced by coronary microembolization.
Lymphoma, B-Cell
Protective effects of astaxanthin on lipopolysaccharide-induced inflammation in bovine endometrial epithelial cells.
Lymphoma, B-Cell
Protective effects of baicalin in a Caenorhabditis elegans model of Parkinson's disease.
Lymphoma, B-Cell
Protective effects of vortioxetine in predator scent stress model of post-traumatic stress disorder in rats: role on neuroplasticity and apoptosis.
Lymphoma, B-Cell
Protective skin aging effects of cherry blossom extract (Prunus Yedoensis) on oxidative stress and apoptosis in UVB-irradiated HaCaT cells.
Lymphoma, B-Cell
Pterostilbene alleviates hydrogen peroxide-induced oxidative stress via nuclear factor erythroid 2 like 2 pathway in mouse preimplantation embryos.
Lymphoma, B-Cell
Puerarin induces cell apoptosis in human chondrosarcoma cell line SW1353 via inhibition of the PI3K/Akt signaling pathway.
Lymphoma, B-Cell
Puerarin prevents tumor necrosis factor-?-induced apoptosis of PC12 cells via activation of the PI3K/Akt signaling pathway.
Lymphoma, B-Cell
Pygopus2 inhibits the efficacy of paclitaxel-induced apoptosis and induces multidrug resistance in human glioma cells.
Lymphoma, B-Cell
Qilin pills alleviate oligoasthenospermia by inhibiting Bax-caspase-9 apoptosis pathway in the testes of model rats.
Lymphoma, B-Cell
Quercetin Attenuates Brain Oxidative Alterations Induced by Iron Oxide Nanoparticles in Rats.
Lymphoma, B-Cell
Quercetin prevents alcohol-induced liver injury through targeting of PI3K/Akt/nuclear factor-?B and STAT3 signaling pathway.
Lymphoma, B-Cell
Quisqualis indica improves benign prostatic hyperplasia by regulating prostate cell proliferation and apoptosis.
Lymphoma, B-Cell
Radix Kansui Stir-Fried with Vinegar Reduces Radix Kansui-Related Hepatotoxicity in Mice via Mitochondrial Pathway.
Lymphoma, B-Cell
Red Ginseng Administration Before Islet Isolation Attenuates Apoptosis and Improves Islet Function and Transplant Outcome in a Syngeneic Mouse Marginal Islet Mass Model.
Lymphoma, B-Cell
Regulatory mechanism of microRNA-128 in osteosarcoma tumorigenesis and evolution through targeting SASH1.
Lymphoma, B-Cell
Renoprotective effects of emodin against diabetic nephropathy in rat models are mediated via PI3K/Akt/GSK-3? and Bax/caspase-3 signaling pathways.
Lymphoma, B-Cell
Resistance exercise improves short-term memory through inactivation of NF-?B pathway in mice with Parkinson disease.
Lymphoma, B-Cell
Resveratrol induces autophagic apoptosis via the lysosomal cathepsin D pathway in human drug-resistant K562/ADM leukemia cells.
Lymphoma, B-Cell
Resveratrol inhibits oxygen-glucose deprivation-induced MMP-3 expression and cell apoptosis in primary cortical cells via the NF-?B pathway.
Lymphoma, B-Cell
Resveratrol inhibits the proliferation of human melanoma cells by inducing G1/S cell cycle arrest and apoptosis.
Lymphoma, B-Cell
Retinoprotective effect of donepezil in diabetic mice involves mitigation of excitotoxicity and activation of PI3K/mTOR/BCl2 pathway.
Lymphoma, B-Cell
RGFP966 inactivation of the YAP pathway attenuates cardiac dysfunction induced by prolonged hypothermic preservation.
Lymphoma, B-Cell
Rhus javanica Linn protects against hydrogen peroxide?induced toxicity in human Chang liver cells via attenuation of oxidative stress and apoptosis signaling.
Lymphoma, B-Cell
Rictor/Mammalian Target of Rapamycin Complex 2 Signaling Protects Colonocytes from Apoptosis and Prevents Epithelial Barrier Breakdown.
Lymphoma, B-Cell
RKTG overexpression inhibits proliferation and induces apoptosis of human leukemia cells via suppression of the ERK and PI3K/AKT signaling pathways.
Lymphoma, B-Cell
Role and mechanism of hypoxia-inducible factor-1 in cell growth and apoptosis of breast cancer cell line MDA-MB-231.
Lymphoma, B-Cell
Role and potential targeting of hepatic apurinic/apyrimidinic endonuclease-1 and cyclin-dependent kinase-4 in hepatocellular carcinoma.
Lymphoma, B-Cell
Role of the PI3K/AKT signalling pathway in apoptotic cell death in the cerebral cortex of streptozotocin-induced diabetic rats.
Lymphoma, B-Cell
Role of thymoquinone and ebselen in the prevention of sodium arsenite-induced nephrotoxicity in female rats.
Lymphoma, B-Cell
Role of Wnt/?-catenin pathway in inducing autophagy and apoptosis in multiple myeloma cells.
Lymphoma, B-Cell
Rosiglitazone-activated PPAR? induces neurotrophic factor-?1 transcription contributing to neuroprotection.
Lymphoma, B-Cell
Rutin attenuates isoflurane-induced neuroapoptosis via modulating JNK and p38 MAPK pathways in the hippocampi of neonatal rats.
Lymphoma, B-Cell
S100A4 gene silencing in oxygen-induced ischemic retinopathy inhibits retinal neovascularization via down-regulation of CREB expression.
Lymphoma, B-Cell
Sanguisorbae Radix Protects Against 6-Hydroxydopamine-induced Neurotoxicity by Regulating NADPH Oxidase and NF-E2-related Factor-2/Heme Oxygenase-1 Expressions.
Lymphoma, B-Cell
Sedum takesimense Protects PC12 Cells against Corticosterone-Induced Neurotoxicity by Inhibiting Neural Apoptosis.
Lymphoma, B-Cell
Serum-free corneal organ culture medium (SFM) but not conventional minimal essential organ culture medium (MEM) protects human corneal endothelial cells from apoptotic and necrotic cell death.
Lymphoma, B-Cell
Shenxiong glucose injection inhibits H2O2-induced H9c2 cell apoptosis by activating the ERK signaling pathway.
Lymphoma, B-Cell
Shexiang Tongxin dropping pill protects against sodium laurate-induced coronary microcirculatory dysfunction in rats.
Lymphoma, B-Cell
Shikonin inhibits TNF-?-induced growth and invasion of rat aortic vascular smooth muscle cells.
Lymphoma, B-Cell
Shuxuetong injection protects cerebral microvascular endothelial cells against oxygen-glucose deprivation reperfusion.
Lymphoma, B-Cell
Silencing of human phosphatidylethanolamine-binding protein 4 enhances rituximab-induced death and chemosensitization in B-cell lymphoma.
Lymphoma, B-Cell
Silencing of peroxisome proliferator-activated receptor-alpha alleviates myocardial injury in diabetic cardiomyopathy by downregulating 3-hydroxy-3-methylglutaryl-coenzyme A synthase 2 expression.
Lymphoma, B-Cell
Simvastatin Strongly Augments Proapoptotic, Anti-inflammatory and Cytotoxic Activity of Oxicam Derivatives in Doxorubicin-resistant Colon Cancer Cells.
Lymphoma, B-Cell
Sinoporphyrin Sodium-Mediated Sonodynamic Therapy Inhibits RIP3 Expression and Induces Apoptosis in the H446 Small Cell Lung Cancer Cell Line.
Lymphoma, B-Cell
SirT1 mediates hyperbaric oxygen preconditioning-induced ischemic tolerance in rat brain.
Lymphoma, B-Cell
Sodium Tanshinone IIA Sulfonate Attenuates Tumor Oxidative Stress and Promotes Apoptosis in an Intermittent Hypoxia Mouse Model.
Lymphoma, B-Cell
Sodium tanshinone IIA sulfonate prevents radiation-induced damage in primary rat cardiac fibroblasts.
Lymphoma, B-Cell
Soursop fruit extract mitigates scopolamine-induced amnesia and oxidative stress via activating cholinergic and Nrf2/HO-1 pathways.
Lymphoma, B-Cell
Src is the primary target of aripiprazole, an atypical antipsychotic drug, in its anti-tumor action.
Lymphoma, B-Cell
Strong anticancer potential of nano-triterpenoid from Phytolacca decandra against A549 adenocarcinoma via a Ca(2+)-dependent mitochondrial apoptotic pathway.
Lymphoma, B-Cell
Suppression of Cisplatin-Induced Hepatic Injury in Rats Through Alarmin High-Mobility Group Box-1 Pathway by Ganoderma lucidum: Theoretical and Experimental Study.
Lymphoma, B-Cell
Swainsonine induces apoptosis of rat cardiomyocytes via mitochondria?mediated pathway.
Lymphoma, B-Cell
Synergistic effect of celecoxib in tumor necrosis factor?related apoptosis?inducing ligand treatment in osteosarcoma cells.
Lymphoma, B-Cell
Synergistic Effect of Forbesione From Garcinia hanburyi in Combination with 5-Fluorouracil on Cholangiocarcinoma
Lymphoma, B-Cell
Synergistic killing of lung cancer cells by cisplatin and radiation via autophagy and apoptosis.
Lymphoma, B-Cell
Synergistic protection of tetramethylpyrazine phosphate and borneol on brain microvascular endothelium cells injured by hypoxia.
Lymphoma, B-Cell
Synthesis, characterization and antitumor activity of Ln(III) complexes with hydrazone Schiff base derived from 2-acetylpyridine and isonicotinohydrazone.
Lymphoma, B-Cell
T0901317, an Agonist of Liver X Receptors, Attenuates Neuronal Apoptosis in Early Brain Injury after Subarachnoid Hemorrhage in Rats via Liver X Receptors/Interferon Regulatory Factor/P53 Upregulated Modulator of Apoptosis/Dynamin-1-Like Protein Pathway.
Lymphoma, B-Cell
Tanshinone IIA inhibits cell proliferation and tumor growth by downregulating STAT3 in human gastric cancer.
Lymphoma, B-Cell
Tanshinone IIA pretreatment attenuates ischemia/reperfusion-induced renal injury.
Lymphoma, B-Cell
TAT cell-penetrating peptide modulates inflammatory response and apoptosis in human lung epithelial cells.
Lymphoma, B-Cell
Tau phosphorylation and cochlear apoptosis cause hearing loss in 3×Tg-AD Mouse Model of Alzheimer's Disease.
Lymphoma, B-Cell
Taurine Pretreatment Prevents Isoflurane-Induced Cognitive Impairment by Inhibiting ER Stress-Mediated Activation of Apoptosis Pathways in the Hippocampus in Aged Rats.
Lymphoma, B-Cell
Telmisartan inhibits NSCLC A549 cell proliferation and migration by regulating the PI3K/AKT signaling pathway.
Lymphoma, B-Cell
Tetra-arsenic tetra-sulfide induces cell cycle arrest and apoptosis in retinoic acid-resistant acute promyelocytic leukemia cells.
Lymphoma, B-Cell
Tetramethylpyrazine Protects against Early Brain Injury after Experimental Subarachnoid Hemorrhage by Affecting Mitochondrial-Dependent Caspase-3 Apoptotic Pathway.
Lymphoma, B-Cell
The Anti-Cancer Effect of Linusorb B3 from Flaxseed Oil through the Promotion of Apoptosis, Inhibition of Actin Polymerization, and Suppression of Src Activity in Glioblastoma Cells.
Lymphoma, B-Cell
The antioxidant edaravone prevents cardiac dysfunction by suppressing oxidative stress in type 1 diabetic rats and in high-glucose-induced injured H9c2 cardiomyoblasts.
Lymphoma, B-Cell
The Apoptosis Mechanism of Epirubicin Combined with BCG on Human Bladder Cancer Cells.
Lymphoma, B-Cell
The cardioprotective effects of diallyl trisulfide on diabetic rats with ex vivo induced ischemia/reperfusion injury.
Lymphoma, B-Cell
The chemokine CXCL1 and its receptor CXCR2 contribute to chronic stress-induced depression in mice.
Lymphoma, B-Cell
The critical role of HMGA2 in regulation of EMT in epithelial ovarian carcinomas.
Lymphoma, B-Cell
The deleterious effect of stress-induced depression on rat liver: Protective role of resveratrol and dimethyl fumarate via inhibiting the MAPK/ERK/JNK pathway.
Lymphoma, B-Cell
The Effect of Bornyl cis-4-Hydroxycinnamate on Melanoma Cell Apoptosis Is Associated with Mitochondrial Dysfunction and Endoplasmic Reticulum Stress.
Lymphoma, B-Cell
The effect of nicotine and dextrose on endoplasmic reticulum stress in human coronary artery endothelial cells.
Lymphoma, B-Cell
The effects of the 5-HT2A receptor antagonist sarpogrelate hydrochloride on chronic hypoxic pulmonary hypertension in rats.
Lymphoma, B-Cell
The Inhibition Effect of the Seaweed Polyphenol, 7-Phloro-Eckol from Ecklonia Cava on Alcohol-Induced Oxidative Stress in HepG2/CYP2E1 Cells.
Lymphoma, B-Cell
The inhibition of tumor protein p53 by microRNA-151a-3p induced cell proliferation, migration and invasion in nasopharyngeal carcinoma.
Lymphoma, B-Cell
The Molecular Evolution and Functional Divergence of Lamprey Programmed Cell Death Genes.
Lymphoma, B-Cell
The potential protective and therapeutic effects of platelet-rich plasma on ischemia/reperfusion injury following experimental torsion/detorsion of testis in the Albino rat model.
Lymphoma, B-Cell
The Potential Protective Effects of Diosmin on Streptozotocin-Induced Diabetic Cardiomyopathy in Rats.
Lymphoma, B-Cell
The protective effects of exogenous spermine on renal ischemia-reperfusion injury in rats.
Lymphoma, B-Cell
The protective effects of propofol against CoCl2-induced HT22 cell hypoxia injury via PP2A/CAMKII?/nNOS pathway.
Lymphoma, B-Cell
The Protective Role of Selenium Against AFB1-Induced Liver Apoptosis by Death Receptor Pathway in Broilers.
Lymphoma, B-Cell
The role of caspase-dependent and caspase-independent pathways of apoptosis in the premature rupture of the membranes: A case-control study.
Lymphoma, B-Cell
The role of mitogen-activated protein kinase in cadmium-induced primary rat cerebral cortical neurons apoptosis via a mitochondrial apoptotic pathway.
Lymphoma, B-Cell
The traditional Korean herbal medicine Ga-Gam-Nai-Go-Hyan suppresses testosterone-induced benign prostatic hyperplasia by regulating inflammatory responses and apoptosis.
Lymphoma, B-Cell
The transcription factor ZEB1 promotes chemoresistance in prostate cancer cell lines.
Lymphoma, B-Cell
Therapeutic Cell Protective Role of Histochrome under Oxidative Stress in Human Cardiac Progenitor Cells.
Lymphoma, B-Cell
Therapeutic effects of simvastatin combined with kallistatin treatment for pediatric burn patients with sepsis.
Lymphoma, B-Cell
Thymoquinone and Costunolide Induce Apoptosis of Both Proliferative and Doxorubicin-Induced-Senescent Colon and Breast Cancer Cells.
Lymphoma, B-Cell
Thymoquinone from Nigella sativa Seeds Promotes the Antitumor Activity of Noncytotoxic Doses of Topotecan in Human Colorectal Cancer Cells in Vitro.
Lymphoma, B-Cell
TM4SF1 inhibits apoptosis and promotes proliferation, migration and invasion in human gastric cancer cells.
Lymphoma, B-Cell
TNF-?-TNFR signal pathway inhibits autophagy and promotes apoptosis of alveolar macrophages in coal worker's pneumoconiosis.
Lymphoma, B-Cell
Tocilizumab inhibits neuronal cell apoptosis and activates STAT3 in cerebral infarction rat model.
Lymphoma, B-Cell
Toll like receptor 4 signaling pathway participated in Salmonella lipopolysaccharide-induced spleen injury in young chicks.
Lymphoma, B-Cell
Toxicological effects of deltamethrin on quail cerebrum: Weakened antioxidant defense and enhanced apoptosis.
Lymphoma, B-Cell
Trace Mineral Overload Induced Hepatic Oxidative Damage and Apoptosis in Pigs with Long-Term High-Level Dietary Mineral Exposure.
Lymphoma, B-Cell
Training counteracts DEX-induced microvascular rarefaction by improving the balance between apoptotic and angiogenic proteins.
Lymphoma, B-Cell
Trametes robiniophila may induce apoptosis and inhibit MMPs expression in the human gastric carcinoma cell line MKN-45.
Lymphoma, B-Cell
Transferrin-conjugated liposomes loaded with carnosic acid inhibit liver cancer growth by inducing mitochondria-mediated apoptosis.
Lymphoma, B-Cell
Treadmill exercise ameliorates impairment of spatial learning memory in pups born to old and obese mother rats.
Lymphoma, B-Cell
Treadmill exercise reduces spinal cord injury-induced apoptosis by activating the PI3K/Akt pathway in rats.
Lymphoma, B-Cell
Triptolide induces autophagy and apoptosis through ERK activation in human breast cancer MCF-7 cells.
Lymphoma, B-Cell
Triptolide-Mediated Inhibition of Interferon Signaling Enhances Vesicular Stomatitis Virus-Based Oncolysis.
Lymphoma, B-Cell
Ulinastatin attenuates diabetes-induced cardiac dysfunction by the inhibition of inflammation and apoptosis.
Lymphoma, B-Cell
Ulinastatin inhibits cerebral ischemia-induced apoptosis in the hippocampus of gerbils.
Lymphoma, B-Cell
Ulinastatin inhibits high glucose-induced cardiomyocyte apoptosis through activating Akt signaling.
Lymphoma, B-Cell
UNBS5162 inhibits SKOV3 ovarian cancer cell proliferation by regulating the PI3K/AKT signalling pathway.
Lymphoma, B-Cell
Uncovering the Anticancer Mechanism of Compound Sophorae Decoction against Ulcerative Colitis-Related Colorectal Cancer in Mice.
Lymphoma, B-Cell
Upregulation of ARHGAP30 attenuates pancreatic cancer progression by inactivating the ?-catenin pathway.
Lymphoma, B-Cell
Upregulation of let-7f-5p promotes chemotherapeutic resistance in colorectal cancer by directly repressing several pro-apoptotic proteins.
Lymphoma, B-Cell
Upregulation of microRNA-351 exerts protective effects during sepsis by ameliorating skeletal muscle wasting through the Tead-4-mediated blockade of the Hippo signaling pathway.
Lymphoma, B-Cell
Upregulation of Yes-associated protein and transcriptional co-activator with PDZ-binding motif influences the behavior of LOVO human colon adenocarcinoma cells.
Lymphoma, B-Cell
Ursolic Acid Causes Cell Death in PC-12 Cells by Inducing Apoptosis and Impairing Autophagy.
Lymphoma, B-Cell
Ursolic acid inhibits the invasive phenotype of SNU-484 human gastric cancer cells.
Lymphoma, B-Cell
V8 induces apoptosis and the endoplasmic reticulum stress response in human multiple myeloma RPMI 8226 cells via the PERK-eIF2?-ATF4 signaling pathway.
Lymphoma, B-Cell
Vaccarin alleviates hypertension and nephropathy in renovascular hypertensive rats.
Lymphoma, B-Cell
Vascular cell adhesion molecule 1 expression by biliary epithelium promotes persistence of inflammation by inhibiting effector T-cell apoptosis.
Lymphoma, B-Cell
Vitexin reverses the autophagy dysfunction to attenuate MCAO-induced cerebral ischemic stroke via mTOR/Ulk1 pathway.
Lymphoma, B-Cell
Wheatgrass-Derived Polysaccharide Has Antiinflammatory, Anti-Oxidative and Anti-Apoptotic Effects on LPS-Induced Hepatic Injury in Mice.
Lymphoma, B-Cell
Wnt6 contributes tumorigenesis and development of colon cancer via its effects on cell proliferation, apoptosis, cell-cycle and migration.
Lymphoma, B-Cell
Xanthohumol activates the proapoptotic arm of the unfolded protein response in chronic lymphocytic leukemia.
Lymphoma, B-Cell
Zinc Protects against Heat Stress-Induced Apoptosis via the Inhibition of Endoplasmic Reticulum Stress in TM3 Leydig Cells.
Lymphoma, B-Cell
[Celastrol inhibits growth and increases apoptosis of human lung cancer A549 cells].
Lymphoma, B-Cell
[Chronic venous disease increases placental villous angiogenesis and lymphangiogenesis and villous cell apoptosis].
Lymphoma, B-Cell
[Clinical significance of survivin and caspase-3 expression in diffuse large B-cell lymphoma]
Lymphoma, B-Cell
[Effect and mechanism of liraglutide on the apoptosis of human hepatocellular carcinoma HepG2 cells induced with palmitic acid].
Lymphoma, B-Cell
[Effect of metformin on mitochondrial pathway of apoptosis and oxidative stress in cell model of nonalcoholic fatty liver disease].
Lymphoma, B-Cell
[Effects of 7-difluoromethy-5, 4'-dimethoxygenistein on ?stress urinary incontinence model in rats and its mechanisms].
Lymphoma, B-Cell
[Effects of hypoxia-inducible factor 1? on hypoxic tolerance of human amniotic mesenchymal stem cells].
Lymphoma, B-Cell
[Expression of Apoptosis-related Protein Livin and Caspase-3 in Diffuse Large B Cell Lymphoma and Its Clinical Significance].
Lymphoma, B-Cell, Marginal Zone
Increased apoptosis and angiogenesis in gastric low-grade mucosa-associated lymphoid tissue-type lymphoma by Helicobacter heilmannii infection in C57/BL6 mice.
Lymphoma, Follicular
Genetic variants in caspase genes and susceptibility to non-Hodgkin lymphoma.
Lymphoma, Follicular
Molecular and immunohistochemical characterization of B-cell lymphoma-2-negative follicular lymphomas.
Lymphoma, Follicular
Nanofluidic proteomic assay for serial analysis of oncoprotein activation in clinical specimens.
Lymphoma, Follicular
The prevention of spontaneous apoptosis of follicular lymphoma B cells by a follicular dendritic cell line: involvement of caspase-3, caspase-8 and c-FLIP.
Lymphoma, Large B-Cell, Diffuse
Immunohistochemical localization of caspase-3 correlates with clinical outcome in B-cell diffuse large-cell lymphoma.
Lymphoma, Large B-Cell, Diffuse
Mechanisms of JP-8 jet fuel toxicity. I. Induction of apoptosis in rat lung epithelial cells.
Lymphoma, Large B-Cell, Diffuse
Prognostic Significance of Survivin and Caspase-3 Immunohistochemical Expression in Patients with Diffuse Large B-cell Lymphoma Treated with Rituximab and CHOP.
Lymphoma, Large B-Cell, Diffuse
[Clinical significance of survivin and caspase-3 expression in diffuse large B-cell lymphoma]
Lymphoma, Large B-Cell, Diffuse
[Expression of Apoptosis-related Protein Livin and Caspase-3 in Diffuse Large B Cell Lymphoma and Its Clinical Significance].
Lymphoma, Large-Cell, Anaplastic
Caspase-3 activation in systemic anaplastic large-cell lymphoma.
Lymphoma, Large-Cell, Anaplastic
Expression levels of apoptosis-related proteins predict clinical outcome in anaplastic large cell lymphoma.
Lymphoma, Non-Hodgkin
Apoptosis and expression of caspases 3, 6 and 8 in malignant non-Hodgkin's lymphomas.
Lymphoma, Non-Hodgkin
CD40L induces multidrug resistance to apoptosis in breast carcinoma and lymphoma cells through caspase independent and dependent pathways.
Lymphoma, Non-Hodgkin
Drug-free macromolecular therapeutics: Impact of structure on induction of apoptosis in Raji B cells.
Lymphoma, Non-Hodgkin
Frequent nuclear localization of ICAD and cytoplasmic co-expression of caspase-8 and caspase-3 in human lymphomas.
Lymphoma, Non-Hodgkin
Genetic variants in caspase genes and susceptibility to non-Hodgkin lymphoma.
Lymphoma, Non-Hodgkin
Huachansu mediates cell death in non-Hodgkin's lymphoma by induction of caspase-3 and inhibition of MAP kinase.
Lymphoma, Non-Hodgkin
[Expression of survivin and caspase-3 in non-Hodgkin's lymphoma and their clinical significance]
Lymphoma, Non-Hodgkin
[Study on expression of caspase-3 and bcl-2 proteins and their relations with cell apoptosis and proliferation in non-Hodgkin's lymphoma]
Lymphoma, T-Cell
13-methyltetradecanoic acid exhibits anti-tumor activity on T-cell lymphomas in vitro and in vivo by down-regulating p-AKT and activating caspase-3.
Lymphoma, T-Cell, Cutaneous
Arsenic trioxide induces apoptosis of cutaneous T cell lymphoma cells: evidence for a partially caspase-independent pathway and potentiation by ascorbic acid (vitamin C).
Lymphoma, T-Cell, Cutaneous
Photodynamic therapy with the phthalocyanine photosensitizer Pc 4: The case experience with preclinical mechanistic and early clinical-translational studies.
Lymphopenia
Activation of lymphocyte autophagy/apoptosis reflects haemodynamic inefficiency and functional aerobic impairment in patients with heart failure.
Lymphopenia
Correction of immunosuppression in aged septic rats by human ghrelin and growth hormone through the vagus nerve-dependent inhibition of TGF-? production.
Lymphopenia
COVID-19 immune signatures reveal stable antiviral T cell function despite declining humoral responses.
Lymphopenia
Improving the Understanding of the Immunopathogenesis of Lymphopenia as a Correlate of SARS-CoV-2 Infection Risk and Disease Progression in African Patients: Protocol for a Cross-sectional Study.
Lymphopenia
Role of vascular cell adhesion molecules and leukocyte apoptosis in the lymphopenia and thrombocytopenia of patients with severe acute respiratory syndrome (SARS).
Lymphoproliferative Disorders
Death receptor apoptosis signaling mediated by FADD in CD30-positive lymphoproliferative disorders involving the skin.
Macular Degeneration
17?-estradiol ameliorates oxidative stress and blue light-emitting diode-induced retinal degeneration by decreasing apoptosis and enhancing autophagy.
Macular Edema
Effect of the Notch signaling pathway on retinal ganglion cells and its neuroprotection in rats with acute ocular hypertension.
Malaria
Expression of cleaved caspase-3 in renal tubular cells in Plasmodium falciparum malaria patients.
Malaria
Melatonin inhibits free radical-mediated mitochondrial-dependent hepatocyte apoptosis and liver damage induced during malarial infection.
Malaria, Cerebral
Apoptosis in experimental cerebral malaria: spatial profile of cleaved caspase-3 and ultrastructural alterations in different disease stages.
Malaria, Cerebral
Proteolytic breakdown of cytoskeleton induces neurodegeneration during pathology of murine cerebral malaria.
Malaria, Falciparum
Expression of cleaved caspase-3 in renal tubular cells in Plasmodium falciparum malaria patients.
Malnutrition
Effects of dietary protein and calcium on thymus apoptosis induced by fluoride in female rats (Wistar rats).
Malnutrition
Protein Malnutrition Impairs Intestinal Epithelial Cell Turnover, a Potential Mechanism of Increased Cryptosporidiosis in a Murine Model.
Malocclusion
MTORC1 coordinates the autophagy and apoptosis signaling in articular chondrocytes in osteoarthritic temporomandibular joint.
Massive Hepatic Necrosis
Intrahepatic activation of caspases in human fulminant hepatic failure.
Massive Hepatic Necrosis
Iron chelator deferasirox rescued mice from Fas-induced fulminant hepatitis.
Mastocytoma
Trichostatin A induces apoptosis of p815 mastocytoma cells in histone acetylation- and mitochondria-dependent fashion.
Mastocytosis
Kit inhibitor APcK110 induces apoptosis and inhibits proliferation of acute myeloid leukemia cells.
Measles
Deficiency of caspase 3 in tumor xenograft impairs therapeutic effect of measles virus Edmoston strain.
Medulloblastoma
Cleaved caspase-3, caspase-7 and poly (ADP-ribose) polymerase are complementarily but differentially expressed in human medulloblastomas.
Medulloblastoma
Dissipation of potassium and proton gradients inhibits mitochondrial hyperpolarization and cytochrome c release during neural apoptosis.
Medulloblastoma
Effects of matrine on the proliferation and apoptosis of human medulloblastoma cell line D341.
Medulloblastoma
Japanese encephalitis virus NS2B-NS3 protease induces caspase 3 activation and mitochondria-mediated apoptosis in human medulloblastoma cells.
Medulloblastoma
Phosphorylated c-MYC expression in Alzheimer disease, Pick's disease, progressive supranuclear palsy and corticobasal degeneration.
Medulloblastoma
The alkylphospholipid perifosine induces apoptosis and p21-mediated cell cycle arrest in medulloblastoma.
Medulloblastoma
[Effect of matrine on cell apoptosis and proliferation and the apoptosis related proteins of human medulloblastoma D341 cells in vitro].
Megacolon
Expression of caspase-3 in enteric cells is related to development of chagasic megacolon.
Melanoma
13-cis-retinoic acid induces apoptosis by modulating caspase-3, bcl-2, and p53 gene expression and regulates the activation of transcription factors in B16F-10 melanoma cells.
Melanoma
4'-Bromo-resveratrol, a dual Sirtuin-1 and Sirtuin-3 inhibitor, inhibits melanoma cell growth through mitochondrial metabolic reprogramming.
Melanoma
4-Thiazolidinone derivative Les-3833 effectively inhibits viability of human melanoma cells through activating apoptotic mechanisms.
Melanoma
?-Carotene down-regulates inducible nitric oxide synthase gene expression and induces apoptosis by suppressing bcl-2 expression and activating caspase-3 and p53 genes in B16F-10 melanoma cells.
Melanoma
A dermatan sulfate-functionalized biomimetic nanocarrier for melanoma targeted chemotherapy.
Melanoma
A novel C-terminal HSP90 inhibitor KU135 induces apoptosis and cell cycle arrest in melanoma cells.
Melanoma
A Novel Oral Astaxanthin Nanoemulsion from Haematococcus pluvialis Induces Apoptosis in Lung Metastatic Melanoma.
Melanoma
A potential role for resveratrol as a radiation sensitizer for melanoma treatment.
Melanoma
A recombinant protein based on Trypanosoma cruzi surface molecule gp82 induces apoptotic cell death in melanoma cells.
Melanoma
A sphingolipid rich lipid fraction isolated from attenuated Leishmania donovani promastigote induces apoptosis in mouse and human melanoma cells in vitro.
Melanoma
Activation-induced cell death of human melanoma specific cytotoxic T lymphocytes is mediated by apoptosis-inducing factor.
Melanoma
Alpha-lipoic acid alters the antitumor effect of bortezomib in melanoma cells in vitro.
Melanoma
Amentoflavone stimulates apoptosis in B16F-10 melanoma cells by regulating bcl-2, p53 as well as caspase-3 genes and regulates the nitric oxide as well as proinflammatory cytokine production in B16F-10 melanoma cells, tumor associated macrophages and peritoneal macrophages.
Melanoma
Andrographolide induces apoptosis in B16F-10 melanoma cells by inhibiting NF-?B-mediated bcl-2 activation and modulating p53-induced caspase-3 gene expression.
Melanoma
Anti-tumor activities of chondroitinase AC and chondroitinase B: inhibition of angiogenesis, proliferation and invasion.
Melanoma
Anticancer effects of Daidzein against the human melanoma cell lines involves cell cycle arrest, autophagy and deactivation of PI3K/AKT signalling pathways.
Melanoma
Antineoplastic Effects and Mechanisms of a New RGD Chimeric Peptide from Bullfrog Skin on the Proliferation and Apoptosis of B16F10 Cells.
Melanoma
Antiproliferation of melanoma cells by polysaccharide isolated from Zizyphus jujuba.
Melanoma
Antiproliferative Activity of Extracts of Campomanesia adamantium (Cambess.) O. Berg and Isolated Compound Dimethylchalcone Against B16-F10 Murine Melanoma.
Melanoma
Antiproliferative and proapoptotic effects of rapamycin and celecoxib in malignant melanoma cell lines.
Melanoma
Antiproliferative effect of linalool on RPMI 7932 human melanoma cell line: ultrastructural studies.
Melanoma
Antitumorigenic effect of damnacanthal on melanoma cell viability through p53 and NF-?B/caspase-3 signaling pathways.
Melanoma
Apigenin Attenuates Melanoma Cell Migration by Inducing Anoikis through Integrin and Focal Adhesion Kinase Inhibition.
Melanoma
Apoptosis induction in human melanoma cells by inhibition of MEK is caspase-independent and mediated by the Bcl-2 family members PUMA, Bim, and Mcl-1.
Melanoma
Apoptosis of murine melanoma B16-BL6 cells induced by quercetin targeting mitochondria, inhibiting expression of PKC-alpha and translocating PKC-delta.
Melanoma
Apoptotic and anti-adhesion effect of ajoene, a garlic derived compound, on the murine melanoma B16F10 cells: possible role of caspase-3 and the alpha(4)beta(1) integrin.
Melanoma
Apoptotic Effect of Astragalin in Melanoma Skin Cancers via Activation of Caspases and Inhibition of Sry-related HMg-Box Gene 10.
Melanoma
Apoptotic effect of Biophytum sensitivum on B16F-10 cells and its regulatory effects on nitric oxide and cytokine production on tumor-associated macrophages.
Melanoma
Apoptotic effect of eugenol envolves G2/M phase abrogation accompanied by mitochondrial damage and clastogenic effect on cancer cell in vitro.
Melanoma
Basal caspase-3 activity promotes migration, invasion, and vasculogenic mimicry formation of melanoma cells.
Melanoma
Bcl-2 family proteins and cytoskeleton changes involved in DM-1 cytotoxic effect on melanoma cells.
Melanoma
Bee Venom and Its Peptide Component Melittin Suppress Growth and Migration of Melanoma Cells via Inhibition of PI3K/AKT/mTOR and MAPK Pathways.
Melanoma
Blockade of BAFF Receptor BR3 on T Cells Enhances Their Activation and Cytotoxicity.
Melanoma
Blockade of the Fas-triggered intracellular signaling pathway in human melanomas is circumvented by cytotoxic lymphocytes.
Melanoma
Bortezomib/proteasome inhibitor triggers both apoptosis and autophagy-dependent pathways in melanoma cells.
Melanoma
Bosutinib, an SRC inhibitor, induces caspase-independent cell death associated with permeabilization of lysosomal membranes in melanoma cells.
Melanoma
Camphene isolated from essential oil of Piper cernuum (Piperaceae) induces intrinsic apoptosis in melanoma cells and displays antitumor activity in vivo.
Melanoma
Caspase-3 activation in human melanoma A375 cell line by a novel selective sigma-2 agonist.
Melanoma
Caspase-3 cleaves XIAP in a positive feedback loop to sensitize melanoma cells to TRAIL-induced apoptosis.
Melanoma
Cell cycle arrest, extracellular matrix changes and intrinsic apoptosis in human melanoma cells are induced by Boron Neutron Capture Therapy.
Melanoma
Characterization and antitumor activity of the extracellular carbohydrate polymer from the cyanobacterium Synechocystis ?sigF mutant.
Melanoma
Cisplatin down-regulation of cellular Fas-associated death domain-like interleukin-1beta-converting enzyme-like inhibitory proteins to restore tumor necrosis factor-related apoptosis-inducing ligand-induced apoptosis in human melanoma cells.
Melanoma
Cisplatin-induced apoptosis in melanoma cells: role of caspase-3 and caspase-7 in Apaf-1 proteolytic cleavage and in execution of the degradative phases.
Melanoma
Climacostol reduces tumour progression in a mouse model of melanoma via the p53-dependent intrinsic apoptotic programme.
Melanoma
Clinical significance of miR-138 in patients with malignant melanoma through targeting of PDK1 in the PI3K/AKT autophagy signaling pathway.
Melanoma
Comparison of essential oil components and in vitro anticancer activity in wild and cultivated Salvia verbenaca.
Melanoma
Concentration-Dependent Pro- and Antitumor Activities of Quercetin in Human Melanoma Spheroids: Comparative Analysis of 2D and 3D Cell Culture Models.
Melanoma
Cotargeting histone deacetylases and oncogenic BRAF synergistically kills human melanoma cells by necrosis independently of RIPK1 and RIPK3.
Melanoma
Curcumin downregulates the constitutive activity of NF-kappaB and induces apoptosis in novel mouse melanoma cells.
Melanoma
Curcumin induces cell death in human uveal melanoma cells through mitochondrial pathway.
Melanoma
Cytochalasin D, LY294002 and olomoucine synergize in promoting death of melanoma cells through activation of caspase-3 and apoptosis.
Melanoma
Cytotoxic activity of Apomine is due to a novel membrane-mediated cytolytic mechanism independent of apoptosis in the A375 human melanoma cell line.
Melanoma
Deficiency of C-C chemokine receptor 5 suppresses tumor development via inactivation of NF-?B and upregulation of IL-1Ra in melanoma model.
Melanoma
Design and Development of Spray-Dried Microsystems to Improve Technological and Functional Properties of Bioactive Compounds from Hazelnut Shells.
Melanoma
Design, synthesis, and biological activity of a potent Smac mimetic that sensitizes cancer cells to apoptosis by antagonizing IAPs.
Melanoma
Diallyl disulfide induces caspase-dependent apoptosis via mitochondria-mediated intrinsic pathway in B16F-10 melanoma cells by up-regulating p53, caspase-3 and down-regulating pro-inflammatory cytokines and nuclear factor-??-mediated Bcl-2 activation.
Melanoma
Differential sensitivity of breast cancer and melanoma cells to proteasome inhibitor Velcade.
Melanoma
Dihydroartemisinin induces pyroptosis by promoting the AIM2/caspase-3/DFNA5 axis in breast cancer cells.
Melanoma
Dimeric Macrocyclic Antagonists of Inhibitor of Apoptosis Proteins for the Treatment of Cancer.
Melanoma
Dominant negative Rac1 attenuates paclitaxel-induced apoptosis in human melanoma cells through upregulation of heat shock protein 27: a functional proteomic analysis.
Melanoma
Downregulation of Bcl-2 and activation of caspase-8 in the UVB-induced apoptosis of a cultured human melanoma cell line.
Melanoma
Downregulation of survivin expression enhances sensitivity of cultured uveal melanoma cells to cisplatin treatment.
Melanoma
eIF4E Is an Adverse Prognostic Marker of Melanoma Patient Survival by Increasing Melanoma Cell Invasion.
Melanoma
Encorafenib (LGX818), a potent BRAF inhibitor, induces senescence accompanied by autophagy in BRAFV600E melanoma cells.
Melanoma
Enhanced anti-melanoma efficacy of interferon ?-2b via overexpression of ING4 by enhanced Fas/FasL-mediated apoptosis.
Melanoma
Ethanol extract of Lycoris radiata induces cell death in B16F10 melanoma via p38-mediated AP-1 activation.
Melanoma
Ethanolic Extract of Senna velutina Roots: Chemical Composition, In Vitro and In Vivo Antitumor Effects, and B16F10-Nex2 Melanoma Cell Death Mechanisms.
Melanoma
Evaluation of In Vitro Antioxidant and Anticancer Properties of the Aqueous Extract from the Stem Bark of Stryphnodendron adstringens.
Melanoma
Exploring new applications of tulip tree (Liriodendron tulipifera L.): leaf essential oil as apoptotic agent for human glioblastoma.
Melanoma
Expression of peripheral benzodiazepine receptor, PCNA, and caspase-3 in cells of skin melanoma and squamous cell carcinoma.
Melanoma
Flavonoids in Ginkgo biloba fallen leaves induce apoptosis through modulation of p53 activation in melanoma cells.
Melanoma
Fucose-containing sulfated polysaccharides from brown seaweeds inhibit proliferation of melanoma cells and induce apoptosis by activation of caspase-3 in vitro.
Melanoma
Galpha(13) mediates human cytomegalovirus-encoded chemokine receptor US28 induced cell death in melanoma.
Melanoma
Gambogic acid induces apoptosis by regulating the expression of Bax and Bcl-2 and enhancing caspase-3 activity in human malignant melanoma A375 cells.
Melanoma
Genista sessilifolia DC. and Genista tinctoria L. inhibit UV light and nitric oxide-induced DNA damage and human melanoma cell growth.
Melanoma
Harmine activates intrinsic and extrinsic pathways of apoptosis in B16F-10 melanoma.
Melanoma
Hazelnut (Corylus avellana L.) Shells Extract: Phenolic Composition, Antioxidant Effect and Cytotoxic Activity on Human Cancer Cell Lines.
Melanoma
Heterogeneous susceptibility to spontaneous and induced apoptosis characterizes two related transplantable melanomas with different biological properties.
Melanoma
Hispolon decreases melanin production and induces apoptosis in melanoma cells through the downregulation of tyrosinase and microphthalmia-associated transcription factor (MITF) expressions and the activation of caspase-3, -8 and -9.
Melanoma
Hyperthermia Suppresses Post - In Vitro Proliferation and Tumor Growth in Murine Malignant Melanoma and Colon Carcinoma.
Melanoma
IFN-beta pretreatment sensitizes human melanoma cells to TRAIL/Apo2 ligand-induced apoptosis.
Melanoma
IL-24 gene transfer sensitizes melanoma cells to erlotinib through modulation of the Apaf-1 and Akt signaling pathways.
Melanoma
IL-32? has differential effects on proliferation and apoptosis of human melanoma cell lines.
Melanoma
Induction of Apoptosis by an Extract of Persian Gulf Marine Mollusc, Turbo Coronatus through the Production of Reactive
Oxygen Species in Mouse Melanoma Cells
Melanoma
Induction of IRAK-M in melanoma induces caspase-3 dependent apoptosis by reducing TRAF6 and calpastatin levels.
Melanoma
Induction of melanoma cell apoptosis and inhibition of tumor growth using a cell-permeable Survivin antagonist.
Melanoma
Induction of T helper 17 cell response by interleukin-7 in patients with primary cutaneous melanoma.
Melanoma
Influence of 28-O-propynoylbetulin on proliferation and apoptosis of melanotic and amelanotic human melanoma cells.
Melanoma
Inhibition of CaMKII-mediated c-FLIP expression sensitizes malignant melanoma cells to TRAIL-induced apoptosis.
Melanoma
Inhibitory activity of acteoside in melanoma via regulation of the ER?-Ras/Raf1-STAT3 pathway.
Melanoma
Inhibitory effect of quercetin on epithelial to mesenchymal transition in SK-MEL-28 human melanoma cells defined by in vitro analysis on 3D collagen gels.
Melanoma
Involvement of ER stress and activation of apoptotic pathways in fisetin induced cytotoxicity in human melanoma.
Melanoma
Label-Free Infrared Spectral Histology of Skin Tissue Part II: Impact of a Lumican-Derived Peptide on Melanoma Growth.
Melanoma
Lauroside B, a megastigmane glycoside from Laurus nobilis (bay laurel) leaves, induces apoptosis in human melanoma cell lines by inhibiting NF-?B activation.
Melanoma
LC3B upregulation by NANOG promotes immune resistance and stem-like property through hyperactivation of EGFR signaling in immune-refractory tumor cells.
Melanoma
Lichen metabolites prevent UV light and nitric oxide-mediated plasmid DNA damage and induce apoptosis in human melanoma cells.
Melanoma
Liver X receptor activation induces apoptosis of melanoma cell through caspase pathway.
Melanoma
Livin/melanoma inhibitor of apoptosis protein as a potential therapeutic target for the treatment of malignancy.
Melanoma
Markers of mitochondrial dysfunction during the diclofenac-induced apoptosis in melanoma cell lines.
Melanoma
MCM7 silencing promotes cutaneous melanoma cell autophagy and apoptosis by inactivating the AKT1/mTOR signaling pathway.
Melanoma
Mechanism of activation of caspase cascade during beta-carotene-induced apoptosis in human tumor cells.
Melanoma
Mechanism of cell death induced by spermine and amine oxidase in mouse melanoma cells.
Melanoma
Melanoma differentiation associated gene-7/interleukin-24 induces caspase-3 denitrosylation to facilitate the activation of cancer cell apoptosis.
Melanoma
MicroRNA-365 promotes apoptosis in human melanoma cell A375 treated with hydatid cyst fluid of Echinococcus granulosus sensu stricto.
Melanoma
Migration and invasion in B16-F10 mouse melanoma cells are regulated by Nrf2 inhibition during treatment with ionizing radiation.
Melanoma
miR-205 suppresses melanoma cell proliferation and induces senescence via regulation of E2F1.
Melanoma
Model systems for rapid and slow induction of apoptosis obtained by inducible expression of pro-apoptotic proteins.
Melanoma
Molecular design and anti-melanoma activity of a novel bullfrog antibacterial peptide RGD-chimera.
Melanoma
Molecular, Biological and Structural Features of VL CDR-1 Rb44 Peptide, Which Targets the Microtubule Network in Melanoma Cells.
Melanoma
Monitoring caspase-3 activation with a multimodality imaging sensor in living subjects.
Melanoma
N-Acetylcysteine enhances UV-mediated caspase-3 activation, fragmentation of E2F-4, and apoptosis in human C8161 melanoma: inhibition by ectopic Bcl-2 expression.
Melanoma
N-Propionyl-Cysteaminylphenol-Magnetite Conjugate (NPrCAP/M) Is a Nanoparticle for the Targeted Growth Suppression of Melanoma Cells.
Melanoma
Natural product corynoline suppresses melanoma cell growth through inducing oxidative stress.
Melanoma
Nitidine chloride efficiently induces autophagy and apoptosis in melanoma cells via AMPK-mTOR signaling pathway.
Melanoma
Non-thermal Plasma Induces Apoptosis in Melanoma Cells via Production of Intracellular Reactive Oxygen Species.
Melanoma
Norcantharidin induces human melanoma A375-S2 cell apoptosis through mitochondrial and caspase pathways.
Melanoma
NQO1-activated phenothiazinium redox cyclers for the targeted bioreductive induction of cancer cell apoptosis.
Melanoma
Overexpression of HSP70 prevents ultraviolet B-induced apoptosis of a human melanoma cell line.
Melanoma
Pharmacology of smac mimetics; chemotype differentiation based on physical association with caspase regulators and cellular transport.
Melanoma
Phosphorothioate oligodeoxynucleotides and G3139 induce apoptosis in 518A2 melanoma cells.
Melanoma
Physalin B from Physalis angulata triggers the NOXA-related apoptosis pathway of human melanoma A375 cells.
Melanoma
Plumbagin enhances TRAIL-mediated apoptosis through up-regulation of death receptor in human melanoma A375 cells.
Melanoma
Precise control of apoptosis via gold nanostars for dose dependent photothermal therapy of melanoma.
Melanoma
Primary cross-resistance to BRAFV600E-, MEK1/2- and PI3K/mTOR-specific inhibitors in BRAF-mutant melanoma cells counteracted by dual pathway blockade.
Melanoma
Pro-oxidative and pro-apoptotic action of defatted seeds of Oenothera paradoxa on human skin melanoma cells.
Melanoma
Propofol promotes apoptosis and suppresses the HOTAIR-mediated mTOR/p70S6K signaling pathway in melanoma cells.
Melanoma
Propranolol induced G0/G1/S phase arrest and apoptosis in melanoma cells via AKT/MAPK pathway.
Melanoma
Protodynamic intracellular acidification by cis-urocanic acid promotes apoptosis of melanoma cells in vitro and in vivo.
Melanoma
Rapid identification of antimicrometastases drugs using integrated model systems with two dimensional monolayer, three dimensional spheroids, and zebrafish xenotransplantation tumors.
Melanoma
Resistance to CD95/Fas-induced and ceramide-mediated apoptosis of human melanoma cells is caused by a defective mitochondrial cytochrome c release.
Melanoma
Resveratrol inhibits the proliferation of human melanoma cells by inducing G1/S cell cycle arrest and apoptosis.
Melanoma
RIN1 exhibits oncogenic property to suppress apoptosis and its aberrant accumulation associates with poor prognosis in melanoma.
Melanoma
RPS3 regulates melanoma cell growth and apoptosis by targeting Cyto C/Ca2+/MICU1 dependent mitochondrial signaling.
Melanoma
Silencing of astrocyte elevated gene-1 inhibits proliferation and migration of melanoma cells and induces apoptosis.
Melanoma
Single-walled carbon nanotube, multi-walled carbon nanotube and Fe2O3 nanoparticles induced mitochondria mediated apoptosis in melanoma cells.
Melanoma
SKLB-M8 induces apoptosis through the AKT/mTOR signaling pathway in melanoma models and inhibits angiogenesis with decrease of ERK1/2 phosphorylation.
Melanoma
SPARC functions as an anti-stress factor by inactivating p53 through Akt-mediated MDM2 phosphorylation to promote melanoma cell survival.
Melanoma
Targeted gold nanorods combined with low-intensity nsPEFs enhance antimelanoma efficacy in vitro.
Melanoma
Targeting the methionine cycle for melanoma therapy with 3-O-(3,4,5-trimethoxybenzoyl)-(-)-epicatechin.
Melanoma
Temozolomide- and fotemustine-induced apoptosis in human malignant melanoma cells: response related to MGMT, MMR, DSBs, and p53.
Melanoma
The Bax/Bcl-2 ratio determines the susceptibility of human melanoma cells to CD95/Fas-mediated apoptosis.
Melanoma
The Combination of Vemurafenib and Procaspase-3 Activation Is Synergistic in Mutant BRAF Melanomas.
Melanoma
The histone deacetylase inhibitor suberic bishydroxamate: a potential sensitizer of melanoma to TNF-related apoptosis-inducing ligand (TRAIL) induced apoptosis.
Melanoma
The In Vitro and In Vivo Anticancer Properties of Chalcone Flavokawain B through Induction of ROS-Mediated Apoptotic and Autophagic Cell Death in Human Melanoma Cells.
Melanoma
The Polysaccharide Extracted from Umbilicaria esculenta Inhibits Proliferation of Melanoma Cells through ROS-Activated Mitochondrial Apoptosis Pathway.
Melanoma
The progression of cell death affects the rejection of allogeneic tumors in immune-competent mice - implications for cancer therapy.
Melanoma
Time dependent appearance of selected apoptotic markers and usefulness of their detection in vitro.
Melanoma
Tissue inhibitor of metalloproteinases-3 induces apoptosis in melanoma cells by stabilization of death receptors.
Melanoma
Tocilizumab unmasks a stage-dependent interleukin-6 component in statin-induced apoptosis of metastatic melanoma cells.
Melanoma
Toward the development of a novel non-RGD cyclic peptide drug conjugate for treatment of human metastatic melanoma.
Melanoma
Tumor necrosis factor-related apoptosis-inducing ligand-induced apoptosis of human melanoma is regulated by smac/DIABLO release from mitochondria.
Melanoma
Ursolic acid induces apoptosis by activating p53 and caspase-3 gene expressions and suppressing NF-kappaB mediated activation of bcl-2 in B16F-10 melanoma cells.
Melanoma
Ursolic acid induces apoptosis through mitochondrial intrinsic pathway and caspase-3 activation in M4Beu melanoma cells.
Melanoma
Vernolide-A, a sesquiterpene lactone from Vernonia cinerea, induces apoptosis in B16F-10 melanoma cells by modulating p53 and caspase-3 gene expressions and regulating NF-?B-mediated bcl-2 activation.
Melanoma
ZNF23 Suppresses Cutaneous Melanoma Cell Malignancy via Mitochondria-Dependent Pathway.
Melanoma
[Apoptin-induced apoptosis of human melanoma cells A375 via activation of caspase-3]
Melanoma
[Apoptosis induced by curcumin and its effect on c-myc and caspase-3 expressions in human melanoma A375 cell line]
Melanoma
[Caspase-3 expression in the tissues of experimental melanoma and its metastases during matrix metalloproteinase-9 inhibition].
Melanoma, Experimental
Antitumor activity of IL-32? through the activation of lymphocytes, and the inactivation of NF-?B and STAT3 signals.
Melanoma, Experimental
Molecular design and anti-melanoma activity of a novel bullfrog antibacterial peptide RGD-chimera.
Melanoma, Experimental
Sphingosine 1-phosphate triggers apoptotic signal for B16 melanoma cells via ERK and caspase activation.
Melanosis
Melanosis coli sparing adenomatous polyps: novel findings using cleaved caspase-3 immunohistochemistry.
MELAS Syndrome
[Expressions of PDCD5 and other apoptosis-related proteins in muscle of patients with mitochondrial cytopathy]
Memory Disorders
Adeno-associated virus vector-mediated expression of DJ-1 attenuates learning and memory deficits in 2, 2´, 4, 4´-tetrabromodiphenyl ether (BDE-47)-treated mice.
Memory Disorders
Agmatine protects against intracerebroventricular streptozotocin-induced water maze memory deficit, hippocampal apoptosis and Akt/GSK3? signaling disruption.
Memory Disorders
Alleviation of lead poisoning in the brain with aqueous leaf extract of the Thunbergia laurifolia (Linn.).
Memory Disorders
Chronic systemic D-galactose exposure induces memory loss, neurodegeneration, and oxidative damage in mice: protective effects of R-alpha-lipoic acid.
Memory Disorders
Guizhi-Fuling-Wan, a Traditional Chinese Herbal Medicine, Ameliorates Memory Deficits and Neuronal Apoptosis in the Streptozotocin-Induced Hyperglycemic Rodents via the Decrease of Bax/Bcl2 Ratio and Caspase-3 Expression.
Memory Disorders
ICV STZ induced impairment in memory and neuronal mitochondrial function: A protective role of nicotinic receptor.
Memory Disorders
Mitochondria in Excitatory and Inhibitory Synapses have Similar Susceptibility to Amyloid-? Peptides Modeling Alzheimer's Disease.
Memory Disorders
PPAR? agonist GW0742 ameliorates A?1-42-induced hippocampal neurotoxicity in mice.
Memory Disorders
Subchronic ketamine alters behaviour, metabolic indices and brain morphology in adolescent rats: Involvement of oxidative stress, glutamate toxicity and caspase-3-mediated apoptosis.
Memory Disorders
The neuroprotection of rattin against amyloid ? peptide in spatial memory and synaptic plasticity of rats.
Memory Disorders
Usnic acid improves memory impairment after cerebral ischemia/reperfusion injuries by anti-neuroinflammatory, anti-oxidant, and anti-apoptotic properties.
Meningioma
Caspase-3 and survivin expression in primary atypical and malignant meningiomas.
Meningioma
Caspase-3 immunohistochemical expression is a marker of apoptosis, increased grade and early recurrence in intracranial meningiomas.
Meningioma
Circulating Tumor Biomarkers in Meningiomas Reveal a Signature of Equilibrium Between Tumor Growth and Immune Modulation.
Meningioma
Detection and quantification of farnesol-induced apoptosis in difficult primary cell cultures by TaqMan protein assay.
Meningioma
Overexpression of midkine contributes to anti-apoptotic effects in human meningiomas.
Meningioma
Transglutaminase 2 expression is increased as a function of malignancy grade and negatively regulates cell growth in meningioma.
Meningitis
Neuroinflammation trajectories precede cognitive impairment after experimental meningitis-evidence from an in vivo PET study.
Meningitis, Bacterial
Expression of death-related proteins in dentate granule cells in human bacterial meningitis.
Meningitis, Pneumococcal
Caspase-3 mediates hippocampal apoptosis in pneumococcal meningitis.
Meningitis, Pneumococcal
Inducible nitric oxide synthase mediates hippocampal caspase-3 activation in pneumococcal meningitis.
Meningoencephalitis
Pathogenesis of Equid Alphaherpesvirus 1 Infection in the Central Nervous System of Mice.
Mesothelioma
Activation and relocalization of caspase 3 during the apoptotic cascade of human mesothelioma cells.
Mesothelioma
An image cytometric technique is a concise method to detect adenoviruses and host cell proteins and to monitor the infection and cellular responses induced.
Mesothelioma
Blockage of epithelial to mesenchymal transition and upregulation of let 7b are critically involved in ursolic acid induced apoptosis in malignant mesothelioma cell.
Mesothelioma
Downregulation of Sp1 is involved in honokiol-induced cell cycle arrest and apoptosis in human malignant pleural mesothelioma cells.
Mesothelioma
Evaluation of apoptosis and immunohistochemical expression of the apoptosis-related proteins in mesothelioma.
Mesothelioma
Hesperidin Induces Apoptosis by Inhibiting Sp1 and Its Regulatory Protein in MSTO-211H Cells.
Mesothelioma
Is survivin expression prognostic or predictive in malignant pleural mesothelioma?
Mesothelioma
mTOR mediates survival signals in malignant mesothelioma grown as tumor fragment spheroids.
Mesothelioma
Overexpression of gamma-glutamylcysteine synthetase in human malignant mesothelioma.
Mesothelioma, Malignant
1-[2-(2-Methoxyphenylamino)ethylamino]-3-(naphthalene-1-yloxy)propan-2-ol as a potential anticancer drug.
Mesothelioma, Malignant
Activation of caspase-3 in malignant mesothelioma induced by asbestiform fiber: an in vivo study.
Mesothelioma, Malignant
Anticarcinogenic effects of halofuginone on lung-derived cancer cells.
Mesothelioma, Malignant
Resistance to caspase-8 and -9 fragments in a malignant pleural mesothelioma cell line with acquired cisplatin-resistance.
Mesothelioma, Malignant
Resveratrol and clofarabine induces a preferential apoptosis-activating effect on malignant mesothelioma cells by Mcl-1 down-regulation and caspase-3 activation.
Metabolic Syndrome
morphological and immunohistochemical features of tissue homeostasis in patients with alopecia areata in the chronic stage associated with metabolic syndrome and the non-burdened course of the disease.
Metrorrhagia
Bcl-2, Fas and caspase 3 expression in endometrium from levonorgestrel implant users with and without breakthrough bleeding.
Microcephaly
Conditional loss of Dicer disrupts cellular and tissue morphogenesis in the cortex and hippocampus.
Microcephaly
Identification of small-molecule inhibitors of Zika virus infection and induced neural cell death via a drug repurposing screen.
Microphthalmos
A dose-response study of a novel method of selective tissue modification of cellular structures in the skin with nanosecond pulsed electric fields.
Mitochondrial Diseases
Mitochondrial cytochrome c release: a factor to consider in mitochondrial disease?
Mitochondrial Encephalomyopathies
[Expressions of PDCD5 and other apoptosis-related proteins in muscle of patients with mitochondrial cytopathy]
Mitochondrial Myopathies
[Expressions of PDCD5 and other apoptosis-related proteins in muscle of patients with mitochondrial cytopathy]
mitochondrial protein-transporting atpase deficiency
HSP70 deficiency results in activation of c-Jun N-terminal Kinase, extracellular signal-regulated kinase, and caspase-3 in hyperosmolarity-induced apoptosis.
Mouth Neoplasms
?-Phenethyl isothiocyanate induces death receptor 5 to induce apoptosis in human oral cancer cells via p38.
Mouth Neoplasms
Anticancer Activity of Apaziquone in Oral Cancer Cells and Xenograft Model: Implications for Oral Cancer Therapy.
Mouth Neoplasms
Apoptosis induced by caffeic acid phenethyl ester in human oral cancer cell lines: Involvement of Puma and Bax activation.
Mouth Neoplasms
Apoptotic effects of dehydrocrenatidine via JNK and ERK pathway regulation in oral squamous cell carcinoma.
Mouth Neoplasms
Areca nut extract demonstrated apoptosis-inducing mechanism by increased caspase-3 activities on oral squamous cell carcinoma.
Mouth Neoplasms
Celecoxib derivatives induce apoptosis via the disruption of mitochondrial membrane potential and activation of caspase 9.
Mouth Neoplasms
Curcuminoids combined with gefitinib mediated apoptosis and autophagy of human oral cancer SAS cells in vitro and reduced tumor of SAS cell xenograft mice in vivo.
Mouth Neoplasms
Cyclin D1 overexpression enhances chemosensitivity to TPF chemotherapeutic agents via the caspase-3 pathway in oral cancer.
Mouth Neoplasms
Danshen extract circumvents drug resistance and represses cell growth in human oral cancer cells.
Mouth Neoplasms
Development of peptide inhibitor as a therapeutic agent against head and neck squamous cell carcinoma (HNSCC) targeting p38? MAP kinase.
Mouth Neoplasms
Effect of protein kinase C alpha, caspase-3, and survivin on apoptosis of oral cancer cells induced by staurosporine.
Mouth Neoplasms
Endoplasmic reticulum stress is involved in hydrogen peroxide induced apoptosis in immortalized and malignant human oral keratinocytes.
Mouth Neoplasms
Extracellular 2'5'-oligoadenylate synthetase 2 mediates T-cell receptor CD3-? chain down-regulation via caspase-3 activation in oral cancer.
Mouth Neoplasms
Extract of Coptidis rhizoma induces cytochrome-c dependent apoptosis in immortalized and malignant human oral keratinocytes.
Mouth Neoplasms
Immunoexpression of cleaved caspase-3 shows lower apoptotic area indices in lip carcinomas than in intraoral cancer.
Mouth Neoplasms
Impacts of survivin and caspase-3 on apoptosis and angiogenesis in oral cancer.
Mouth Neoplasms
In Vitro Assessment of the Anticancer Potential of Evodiamine in Human Oral Cancer Cell Lines.
Mouth Neoplasms
Iron chelator-induced growth arrest and cytochrome c-dependent apoptosis in immortalized and malignant oral keratinocytes.
Mouth Neoplasms
Kaempferol and quercetin, components of Ginkgo biloba extract (EGb 761), induce caspase-3-dependent apoptosis in oral cavity cancer cells.
Mouth Neoplasms
Licochalcone A as a potent antitumor agent suppresses growth of human oral cancer SCC-25 cells in vitro via caspase-3 dependent pathways.
Mouth Neoplasms
Manoalide Preferentially Provides Antiproliferation of Oral Cancer Cells by Oxidative Stress-Mediated Apoptosis and DNA Damage.
Mouth Neoplasms
Mechanism of sappanchalcone-induced growth inhibition and apoptosis in human oral cancer cells.
Mouth Neoplasms
MicroRNA-205 suppresses the oral carcinoma oncogenic activity via down-regulation of Axin-2 in KB human oral cancer cell.
Mouth Neoplasms
Polyphyllin G induces apoptosis and autophagy cell death in human oral cancer cells.
Mouth Neoplasms
Repression of caspase-3 and RNA-binding protein HuR cleavage by cyclooxygenase-2 promotes drug resistance in oral squamous cell carcinoma.
Mouth Neoplasms
Selective cytotoxic effects of low-power laser irradiation on human oral cancer cells.
Mouth Neoplasms
[Expression of survivin, caspase-3 in oral precancerous lesions and oral squamous-cell carcinoma.]
Movement Disorders
Activation of striatal inflammatory mediators and caspase-3 is central to haloperidol-induced orofacial dyskinesia.
Mucocutaneous Lymph Node Syndrome
A replication study for association of ITPKC and CASP3 two-locus analysis in IVIG unresponsiveness and coronary artery lesion in Kawasaki disease.
Mucocutaneous Lymph Node Syndrome
Association of TNF-? rs1800629, CASP3 rs72689236 and FCGR2A rs1801274 Polymorphisms with Susceptibility to Kawasaki Disease: A Comprehensive Meta-Analysis.
Mucocutaneous Lymph Node Syndrome
CASP3 gene single-nucleotide polymorphism (rs72689236) and Kawasaki disease in Taiwanese children.
Mucocutaneous Lymph Node Syndrome
Common variants in CASP3 confer susceptibility to Kawasaki disease.
Mucocutaneous Lymph Node Syndrome
ITPKC and CASP3 polymorphisms and risks for IVIG unresponsiveness and coronary artery lesion formation in Kawasaki disease.
Mucocutaneous Lymph Node Syndrome
Meta-analysis of the relationship between single nucleotide polymorphism rs72689236 of caspase-3 and Kawasaki disease.
Mucocutaneous Lymph Node Syndrome
Retraction Note to: Meta-analysis of the relationship between single nucleotide polymorphism rs72689236 of caspase-3 and Kawasaki disease.
Mucocutaneous Lymph Node Syndrome
[Association of CASP3 gene single nucleotide polymorphisms with Kawasaki disease in Chinese children patients].
Mucocutaneous Lymph Node Syndrome
[Association of new functional SNP rs72689236 of CASP3 with Kawasaki disease: a meta-analysis].
Multiple Myeloma
A Gli inhibitor GANT61 suppresses cell proliferation, promotes cell apoptosis and induces G1/G0 cycle retardation with a dose- and time-dependent manner through inhibiting Notch pathway in multiple myeloma.
Multiple Myeloma
A novel small molecule inhibits STAT3 phosphorylation and DNA binding activity and exhibits potent growth suppressive activity in human cancer cells.
Multiple Myeloma
Accessory Cells of the Microenvironment Protect Multiple Myeloma from T-Cell Cytotoxicity through Cell Adhesion-Mediated Immune Resistance.
Multiple Myeloma
Alantolactone induces G1 phase arrest and apoptosis of multiple myeloma cells and overcomes bortezomib resistance.
Multiple Myeloma
Arsenic trioxide induces multiple myeloma cell apoptosis via disruption of mitochondrial transmembrane potentials and activation of caspase-3.
Multiple Myeloma
Combined treatment with bortezomib plus bafilomycin A1 enhances the cytocidal effect and induces endoplasmic reticulum stress in U266 myeloma cells: crosstalk among proteasome, autophagy-lysosome and ER stress.
Multiple Myeloma
Cytotoxicity of Gymnopilus purpureosquamulosus extracts on hematologic malignant cells through activation of the SAPK/JNK signaling pathway.
Multiple Myeloma
Effects of Arsenic Trioxide Combined with Bortezomib on Apoptosis of Multiple Myeloma Cell Line KM3 and Its Mechanisms.
Multiple Myeloma
Effects of DTX3L on the cell proliferation, adhesion, and drug resistance of multiple myeloma cells.
Multiple Myeloma
Effects of gambogic acid on the activation of caspase-3 and downregulation of SIRT1 in RPMI-8226 multiple myeloma cells via the accumulation of ROS.
Multiple Myeloma
Enhancing therapeutic efficacy of oncolytic vaccinia virus armed with Beclin-1, an autophagic Gene in leukemia and myeloma.
Multiple Myeloma
Importin-? and exportin-5 are strong biomarkers of productive reoviral infection of cancer cells.
Multiple Myeloma
MIR145-3p promotes autophagy and enhances bortezomib sensitivity in multiple myeloma by targeting HDAC4.
Multiple Myeloma
[Ad-NK4 Enhances the Chemosensitivity of Human Multiple Myeloma RPMI 8226 Cells to Bortezomib].
Multiple Myeloma
[Effect of AZD8330 on proliferation and apoptosis of multiple myeloma cells].
Multiple Myeloma
[Effects of docetaxel on proliferation and apoptosis of human multiple myeloma cell RPMI8226].
Multiple Sclerosis
A role for caspase-1 and -3 in the pathology of experimental allergic encephalomyelitis : inflammation versus degeneration.
Multiple System Atrophy
Failure of caspase inhibition in the double-lesion rat model of striatonigral degeneration (multiple system atrophy).
Muscle Spasticity
Caspase inhibitors prevent endothelial apoptosis and cerebral vasospasm in dog model of experimental subarachnoid hemorrhage.
Muscular Atrophy
Absence of Caspase-3 Protects Against Denervation Induced Skeletal Muscle Atrophy.
Muscular Atrophy
Apoptotic mediators are upregulated in the skeletal muscle of chronic/progressive mouse model of Parkinson's disease.
Muscular Atrophy
Calpain and capase-3 play required roles in immobilization-induced limb muscle atrophy.
Muscular Atrophy
Caspase-3 cleaves the expanded androgen receptor protein of spinal and bulbar muscular atrophy in a polyglutamine repeat length-dependent manner.
Muscular Atrophy
Denervation Dynamically Regulates Integrin alpha7 Signaling Pathways and Microscopic Structures in Rats.
Muscular Atrophy
Effects of exogenous neurotrophin-3 on myocyte apoptosis and Ca(2+)-ATP enzyme levels following nerve injury in rats.
Muscular Atrophy
Immobilization-induced activation of key proteolytic systems in skeletal muscles is prevented by a mitochondria-targeted antioxidant.
Muscular Atrophy
Lack of caspase-3 attenuates immobilization-induced muscle atrophy and loss of tension generation along with mitigation of apoptosis and inflammation.
Muscular Atrophy
Mechanism of attenuation of skeletal muscle atrophy by zinc-alpha2-glycoprotein.
Muscular Atrophy
Muscle protein breakdown has a minor role in the protein anabolic response to essential amino acid and carbohydrate intake following resistance exercise.
Muscular Atrophy
Muscle proteolytic system modulation through the effect of taurine on mice bearing muscular atrophy.
Muscular Atrophy
Positive end-expiratory airway pressure does not aggravate ventilator-induced diaphragmatic dysfunction in rabbits.
Muscular Atrophy
Regulation of caspase-3 activity by insulin in skeletal muscle cells involves both PI3-kinase and MEK-1/2.
Muscular Atrophy
Resveratrol Improves Muscle Atrophy By Modulating Mitochondrial Quality Control In STZ-Induced Diabetic Mice.
Muscular Atrophy
Superoxide-mediated oxidative stress accelerates skeletal muscle atrophy by synchronous activation of proteolytic systems.
Muscular Atrophy
The activation of apoptosis factor in hindlimb unloading-induced muscle atrophy under normal and low-temperature environmental conditions.
Muscular Atrophy
[Effects of Electroacupuncture on Apoptosis-related Protein Expression of Gastrocnemius Muscle Cells in Rats with Denervated Sciatic Nerve].
Muscular Diseases
[Effect of electroacupuncture on expression of caspase-3 and phosphorylated Akt proteins in the skeleton muscle in diabetic mice].
Muscular Disorders, Atrophic
Calpain and capase-3 play required roles in immobilization-induced limb muscle atrophy.
Muscular Dystrophies
Caspase 3 expression correlates with skeletal muscle apoptosis in Duchenne and facioscapulo human muscular dystrophy. A potential target for pharmacological treatment?
Myalgia
Investigation of the relationships between different enzymes and postmortem duck muscle tenderization.
Myasthenia Gravis
Decreased expression of c-myc family genes in thymuses from myasthenia gravis patients.
Myasthenia Gravis
Increased Bax/Bcl-2 ratio up-regulates caspase-3 and increases apoptosis in the thymus of patients with myasthenia gravis.
Myelodysplastic Syndromes
A novel histone deacetylase inhibitor Chidamide induces G0/G1 arrest and apoptosis in myelodysplastic syndromes.
Myelodysplastic Syndromes
Analysis of Aurora kinase A expression in CD34(+) blast cells isolated from patients with myelodysplastic syndromes and acute myeloid leukemia.
Myelodysplastic Syndromes
Proliferation and apoptosis in acute and chronic leukemias and myelodysplastic syndrome.
Myocardial Infarction
Activation of Akt/GSK-3beta signaling pathway is involved in intermedin(1-53) protection against myocardial apoptosis induced by ischemia/reperfusion.
Myocardial Infarction
Acute oxygen-ozone administration to rats protects the heart from ischemia reperfusion infarct.
Myocardial Infarction
Aloe-emodin attenuates myocardial infarction and apoptosis via up-regulating miR-133 expression.
Myocardial Infarction
An in silico appraisal to identify high affinity anti-apoptotic synthetic tetrapeptide inhibitors targeting the mammalian caspase 3 enzyme.
Myocardial Infarction
Analyzing the anti-ischemia-reperfusion injury effects of ginsenoside Rb1 mediated through the inhibition of p38? MAPK.
Myocardial Infarction
Antiapoptotic effect of implanted embryonic stem cell-derived early-differentiated cells in aging rats after myocardial infarction.
Myocardial Infarction
Antiapoptotic mechanisms of Chinese medicine formula, Guan-Xin-Er-Hao, in the rat ischemic heart.
Myocardial Infarction
Antioxidants attenuate myocyte apoptosis in the remote non-infarcted myocardium following large myocardial infarction.
Myocardial Infarction
Apoptosis at a distance: remote activation of caspase-3 occurs early after myocardial infarction.
Myocardial Infarction
Atractylodesin III maintains mitochondrial function and inhibits caspase-3 activity to reverse apoptosis of cardiomyocytes in AMI rats.
Myocardial Infarction
Baicalin ameliorates isoproterenol-induced acute myocardial infarction through iNOS, inflammation and oxidative stress in rat.
Myocardial Infarction
Berberine inhibits cardiac remodeling of heart failure after myocardial infarction by reducing myocardial cell apoptosis in rats.
Myocardial Infarction
Bifidobacterium longum R0175 attenuates post-myocardial infarction depressive-like behaviour in rats.
Myocardial Infarction
Calcium sensing receptor involving in therapy of embryonic stem cell transplantation alleviates acute myocardial infarction by inhibiting apoptosis and oxidative stress in rats.
Myocardial Infarction
Calcium-sensing receptor-mediated mitogen-activated protein kinase pathway improves the status of transplanted mouse embryonic stem cells in rats with acute myocardial infarction.
Myocardial Infarction
Calpain and caspase-3 inhibitors reduce infarct size and post-ischemic apoptosis in rat heart without modifying contractile recovery.
Myocardial Infarction
Carvedilol Enhances Mesenchymal Stem Cell Therapy for Myocardial Infarction via Inhibition of Caspase-3 Expression.
Myocardial Infarction
Caspase-3 Activity in the Rat Amygdala Measured by Spectrofluorometry After Myocardial Infarction.
Myocardial Infarction
Deferoxamine-activated hypoxia-inducible factor-1 restores cardioprotective effects of sevoflurane postconditioning in diabetic rats.
Myocardial Infarction
Deficiency in TLR4 signal transduction ameliorates cardiac injury and cardiomyocyte contractile dysfunction during ischemia.
Myocardial Infarction
Dexmedetomidine alleviates cardiomyocyte apoptosis and cardiac dysfunction may be associated with inhibition of RhoA/ROCK pathway in mice with myocardial infarction.
Myocardial Infarction
Donor MSCs release apoptotic bodies to improve myocardial infarction via autophagy regulation in recipient cells.
Myocardial Infarction
Edaravone and benidipine protect myocardial damage by regulating mitochondrial stress, apoptosis signalling and cardiac biomarkers against doxorubicin-induced cardiotoxicity.
Myocardial Infarction
Effect of olprinone on ischemia-reperfusion induced myocardial injury in rats.
Myocardial Infarction
Effects of isoflurane preconditioning in the delayed phase on myocardial tumor necrosis factor alpha levels and caspase-3 protein expression in a rabbit model of ischemia-reperfusion injury.
Myocardial Infarction
Endocrine Protection of Ischemic Myocardium by FGF21 from the Liver and Adipose Tissue.
Myocardial Infarction
ERK-MAPK signaling opposes Rho-kinase to reduce cardiomyocyte apoptosis in heart ischemic preconditioning.
Myocardial Infarction
Experimental acute myocardial infarction in rats: HIF-1?, caspase-3, erythropoietin and erythropoietin receptor expression and the cardioprotective effects of two different erythropoietin doses.
Myocardial Infarction
Histological differences in healing following experimental transmural infarction in rats.
Myocardial Infarction
Hydrogen sulfide protects cardiomyocytes from myocardial ischemia-reperfusion injury by enhancing phosphorylation of apoptosis repressor with caspase recruitment domain.
Myocardial Infarction
Hydroxytyrosol Protects against Myocardial Ischemia/Reperfusion Injury through a PI3K/Akt-Dependent Mechanism.
Myocardial Infarction
Immunohistochemical expression of activated caspase-3 in human myocardial infarction.
Myocardial Infarction
Influences of remifentanil on myocardial ischemia-reperfusion injury and the expressions of Bax and Bcl-2 in rats.
Myocardial Infarction
JNK/PI3K/Akt signaling pathway is involved in myocardial ischemia/reperfusion injury in diabetic rats: effects of salvianolic acid A intervention.
Myocardial Infarction
Lentivirus mediated interference of Caspase-3 expression ameliorates the heart function on rats with acute myocardial infarction.
Myocardial Infarction
let-7b suppresses apoptosis and autophagy of human mesenchymal stem cells transplanted into ischemia/reperfusion injured heart 7by targeting caspase-3.
Myocardial Infarction
Mediation of exogenous hydrogen sulfide in recovery of ischemic post-conditioning-induced cardioprotection via down-regulating oxidative stress and up-regulating PI3K/Akt/GSK-3? pathway in isolated aging rat hearts.
Myocardial Infarction
MicroRNA-760-mediated low expression of DUSP1 impedes the protective effect of NaHS on myocardial ischemia-reperfusion injury.
Myocardial Infarction
MiR-124 Regulates the Inflammation and Apoptosis in Myocardial Infarction Rats by Targeting STAT3.
Myocardial Infarction
miR-129 Attenuates Myocardial Ischemia Reperfusion Injury by Regulating the Expression of PTEN in Rats.
Myocardial Infarction
MiR-808 inhibits cardiomyocyte apoptosis and expressions of caspase-3 and caspase-9 in rats with myocardial infarction by regulating TGF-?1 signaling pathway.
Myocardial Infarction
PD150606 protects against ischemia/reperfusion injury by preventing ?-calpain-induced mitochondrial apoptosis.
Myocardial Infarction
Post-ischemic cardioprotection by A2A adenosine receptors: dependent of phosphatidylinositol 3-kinase pathway.
Myocardial Infarction
Pravastatin improves risk factors but not ischaemic tolerance in obese rats.
Myocardial Infarction
Protection of the myocardium against ischemia/reperfusion injury by punicalagin through an SIRT1-NRF-2-HO-1-dependent mechanism.
Myocardial Infarction
Protective Effect of Apigenin on Ischemia/Reperfusion Injury of the Isolated Rat Heart.
Myocardial Infarction
Protective Effects of Kaempferol against Myocardial Ischemia/Reperfusion Injury in Isolated Rat Heart via Antioxidant Activity and Inhibition of Glycogen Synthase Kinase-3?.
Myocardial Infarction
Research on protective mechanism of ibuprofen in myocardial ischemia-reperfusion injury in rats through the PI3K/Akt/mTOR signaling pathway.
Myocardial Infarction
Role of Janus kinase 2/signal transducer and activator of transcription 3 signaling pathway in cardioprotection of exercise preconditioning.
Myocardial Infarction
Rosiglitazone inhibits hypercholesterolaemia-induced myeloperoxidase upregulation--a novel mechanism for the cardioprotective effects of PPAR agonists.
Myocardial Infarction
Serum caspase-3 p17 fragment is elevated in patients with ST-segment elevation myocardial infarction: a novel observation.
Myocardial Infarction
Sevoflurane post-conditioning reduces rat myocardial ischemia reperfusion injury through an increase in NOS and a decrease in phopshorylated NHE1 levels.
Myocardial Infarction
Sphingosine 1-Phosphate Postconditioning Protects Against Myocardial Ischemia/reperfusion Injury in Rats via Mitochondrial Signaling and Akt-Gsk3? Phosphorylation.
Myocardial Infarction
Stem cell antigen 1 protects against cardiac hypertrophy and fibrosis after pressure overload.
Myocardial Infarction
Sufentanil postconditioning protects the myocardium from ischemia-reperfusion via PI3K/Akt-GSK-3? pathway.
Myocardial Infarction
The Cardioprotective Effects of Remote Ischemic Conditioning in a Rat Model of Acute Myocardial Infarction.
Myocardial Infarction
The PI3K/Akt pathway mediates the protection of SO2 preconditioning against myocardial ischemia/reperfusion injury in rats.
Myocardial Infarction
The protective role of hydrogen sulfide in myocardial ischemia-reperfusion-induced injury in diabetic rats.
Myocardial Infarction
The Protective Role of Interleukin-33 in Myocardial Ischemia and Reperfusion Is Associated with Decreased HMGB1 Expression and Up-Regulation of the P38 MAPK Signaling Pathway.
Myocardial Infarction
Tissue kallikrein infusion prevents cardiomyocyte apoptosis, inflammation and ventricular remodeling after myocardial infarction.
Myocardial Infarction
Uric acid aggravates myocardial ischemia-reperfusion injury via ROS/NLRP3 pyroptosis pathway.
Myocardial Infarction
[Activation of JAK2/STAT3 pathway by CPU0213 alleviates myocardial ischemia-reperfusion and oxidative stress injury in rats].
Myocardial Infarction
[Effect of astragalus injection on left ventricular remodeling and apoptotic gene caspase-3 in rats after myocardial infarction]
Myocardial Infarction
[Liraglutide attenuates myocardial ischemia/reperfusion injury possibly through reducing cardiomyocytes apoptosis and oxidation in rats].
Myocardial Infarction
[Mechanism of Xuefu Zhuyu Decoction in treatment of myocardial infarction based on network pharmacology and molecular docking].
Myocardial Infarction
[Role of mitochondrial permeability transition pore in mediating the effect of endomorphin-1 postconditioning against myocardial ischemia-reperfusion injury in rats].
Myocardial Ischemia
Co-localization of the cysteine protease caspase-3 with apoptotic myocytes after in vivo myocardial ischemia and reperfusion in the rat.
Myocardial Ischemia
Oligophrenin1 protects mice against myocardial ischemia and reperfusion injury by modulating inflammation and myocardial apoptosis.
Myocardial Ischemia
p38 mitogen activated protein kinase mediates both death signaling and functional depression in the heart.
Myocardial Ischemia
Proapoptotic effects of caspase-1/interleukin-converting enzyme dominate in myocardial ischemia.
Myocardial Ischemia
Role of Janus kinase 2/signal transducer and activator of transcription 3 signaling pathway in cardioprotection of exercise preconditioning.
Myocardial Ischemia
The effects of simvastatin preconditioning on the expression of caspase-3 after myocardial ischemia reperfusion injury in rats.
Myocardial Ischemia
Time-Course of the Effects of QSYQ in Promoting Heart Function in Ameroid Constrictor-Induced Myocardial Ischemia Pigs.
Myocardial Ischemia
[The effects of salidroside on the apoptosis pathway of myocardial cells in acute exhausted rats].
Myocardial Reperfusion Injury
Increased cardiomyocyte apoptosis following ischemia and reperfusion in diet-induced hypercholesterolemia: relation to Bcl-2 and Bax proteins and caspase-3 activity.
Myocardial Stunning
Inhibition of caspase-3 improves contractile recovery of stunned myocardium, independent of apoptosis-inhibitory effects.
Myocarditis
Cardiac-specific overexpression of melanoma differentiation-associated gene-5 protects mice from lethal viral myocarditis.
Myocarditis
Heme oxygenase-1 mediates oxidative stress and apoptosis in coxsackievirus b3-induced myocarditis.
Myocarditis
MicroRNA-425-3p inhibits myocardial inflammation and cardiomyocyte apoptosis in mice with viral myocarditis through targeting TGF-?1.
Myocarditis
[Expression of VCAM-1 and caspase-3 in myocardium of persons who died from viral myocarditis].
Myocarditis
[The mechanisms responsible for the therapeutic effects of anti-Fas ligand antibody on viral myocarditis in mice]
Myoclonic Epilepsies, Progressive
A novel autosomal dominant spinocerebellar ataxia (SCA16) linked to chromosome 8q22.1-24.1.
Myoclonic Epilepsies, Progressive
Dentatorubral pallidoluysian atrophy (DRPLA) protein is cleaved by caspase-3 during apoptosis.
Myoepithelioma
Evidence that transgenes encoding components of the Wnt signaling pathway preferentially induce mammary cancers from progenitor cells.
Myoma
Changes in proliferating and apoptotic markers of leiomyoma following treatment with a selective progesterone receptor modulator or gonadotropin-releasing hormone agonist.
Myoma
In vivo mechanisms of uterine myoma volume reduction with ulipristal acetate treatment.
Myoma
Processes of apoptosis and cell proliferation in uterine myomas originating from reproductive and perimenopausal women.
Myopia
[The treatment of retinal apoptosis by Caspase 3 inhibitor Ac-DEVD-CHO in experimental myopia]
Myositis
Expression of human IAP-like protein in skeletal muscle: a possible explanation for the rare incidence of muscle fiber apoptosis in T-cell mediated inflammatory myopathies.
Myxoma
Cell cycle and apoptosis regulatory proteins, proliferative markers, cell signaling molecules, CD209, and decorin immunoreactivity in low-grade myxofibrosarcoma and myxoma.
Myxoma
Tumorigenic poxviruses up-regulate intracellular superoxide to inhibit apoptosis and promote cell proliferation.
nadh:ubiquinone reductase (h+-translocating) deficiency
Prostaglandin A1 inhibits rotenone-induced apoptosis in SH-SY5Y cells.
Nasal Polyps
Differential expression of Livin, caspase-3, and second mitochondria-derived activator of caspases in chronic rhinosinusitis with nasal polyps.
Nasal Polyps
Expression and distributional patterns of the inhibitor of apoptosis protein family and caspase 3 in nasal polyps.
Nasal Polyps
Expression profiles of CD11b, galectin-1, beclin-1, and caspase-3 in nasal polyposis
Nasal Polyps
[Immunocytochemical detection of caspase 3 in various diseases of human nasal mucosa]
Nasopharyngeal Carcinoma
?-Tocotrienol induces apoptosis and inhibits proliferation of nasopharyngeal carcinoma cells.
Nasopharyngeal Carcinoma
Absence of caspase 3 activation in neoplastic cells of nasopharyngeal carcinoma biopsies predicts rapid fatal outcome.
Nasopharyngeal Carcinoma
CHM-1 Suppresses Formation of Cell Surface-associated GRP78-p85? Complexes, Inhibiting PI3K-AKT Signaling and Inducing Apoptosis of Human Nasopharyngeal Carcinoma Cells.
Nasopharyngeal Carcinoma
DNAzymes targeted to EBV-encoded latent membrane protein-1 induce apoptosis and enhance radiosensitivity in nasopharyngeal carcinoma.
Nasopharyngeal Carcinoma
Effect of RNA interference targeting human telomerase reverse transcriptase on telomerase and its related protein expression in nasopharyngeal carcinoma cells.
Nasopharyngeal Carcinoma
Isoliquiritigenin suppresses the proliferation and induced apoptosis via miR-32/LATS2/Wnt in nasopharyngeal carcinoma.
Nasopharyngeal Carcinoma
Junduqing extractive promotes the apoptosis of nasopharyngeal carcinoma cells through down-regulating Mcl-1 and Bcl-xL and up-regulating Caspase-3, Caspase-8 and Caspase-9.
Nasopharyngeal Carcinoma
MIR106A-5p upregulation suppresses autophagy and accelerates malignant phenotype in nasopharyngeal carcinoma.
Nasopharyngeal Carcinoma
Protein expression and intracellular localization of prostate apoptosis response-4 (Par-4) are associated with apoptosis induction in nasopharyngeal carcinoma cell lines.
Nasopharyngeal Carcinoma
The antitumor effect of resveratrol on nasopharyngeal carcinoma cells.
Nasopharyngeal Carcinoma
WWOX suppresses proliferation and induces apoptosis via G2 arrest and caspase 3 pathway in nasopharyngeal carcinoma cells.
Nasopharyngeal Carcinoma
[Effect of recombinant caspase-3 gene transfection on CNE2 cell apoptosis]
Nasopharyngeal Carcinoma
[Effects of EGCG on the nasopharyngeal carcinoma cell line CNE-2 and the expression of related gene].
Nasopharyngeal Carcinoma
[The effect of shRNA targeting hTERT on telomerase and the expression of PCNA and Caspase-3 in nasopharyngeal carcinoma cells]
Nasopharyngeal Carcinoma
[The inhibited effect of matrine on human nasopharyngeal carcinoma CNE2 cells and the expression of apoptosis related gene Caspase in vitro].
Nematode Infections
Activation of caspases in intestinal villus epithelial cells of normal and nematode infected rats.
Neoplasm Metastasis
5-Fluorouracil induced Fas upregulation associated with apoptosis in liver metastases of colorectal cancer patients.
Neoplasm Metastasis
A novel HSP90 inhibitor delays castrate resistant prostate cancer without altering serum PSA levels and inhibits osteoclastogenesis.
Neoplasm Metastasis
Active caspase 3 and DNA fragmentation as markers for apoptotic cell death in primary and metastatic liver tumours.
Neoplasm Metastasis
Activin receptor signaling regulates prostatic epithelial cell adhesion and viability.
Neoplasm Metastasis
Alzheimer's drug Memantine inhibits metastasis and p-Erk protein expression on 4T1 breast cancer cells.
Neoplasm Metastasis
Analysis of expression of p63 and caspase-3 and their predictive value in patients with squamous cell carcinoma of maxillary sinus.
Neoplasm Metastasis
Analysis of in vivo patterns of caspase 3 gene expression in primary hepatocellular carcinoma and its relationship to p21(WAF1) expression and hepatic apoptosis.
Neoplasm Metastasis
Antiangiogenic antithrombin induces global changes in the gene expression profile of endothelial cells.
Neoplasm Metastasis
Antitumor and radiosensitizing synergistic effects of apigenin and cryptotanshinone against solid Ehrlich carcinoma in female mice.
Neoplasm Metastasis
Apigenin Attenuates Melanoma Cell Migration by Inducing Anoikis through Integrin and Focal Adhesion Kinase Inhibition.
Neoplasm Metastasis
Basal caspase-3 activity promotes migration, invasion, and vasculogenic mimicry formation of melanoma cells.
Neoplasm Metastasis
Biological factors, tumor growth kinetics, and survival after metastasectomy for pulmonary melanoma.
Neoplasm Metastasis
Blocking circ_0013912 Suppressed Cell Growth, Migration and Invasion of Pancreatic Ductal Adenocarcinoma Cells in vitro and in vivo Partially Through Sponging miR-7-5p.
Neoplasm Metastasis
Caspase-3 enhances lung metastasis and cell migration in a protease-independent mechanism through the ERK pathway.
Neoplasm Metastasis
Caspase-3 regulates the migration, invasion and metastasis of colon cancer cells.
Neoplasm Metastasis
Clinicopathological and prognostic significance of Ki-67, caspase-3 and p53 expression in gastric carcinomas.
Neoplasm Metastasis
Clinicopathological significance of PTEN and Caspase-3 expressions in breast cancer.
Neoplasm Metastasis
Combination therapy with dacarbazine and statins improved the survival rate in mice with metastatic melanoma.
Neoplasm Metastasis
Curcumol inhibits lung adenocarcinoma growth and metastasis via inactivation of PI3K/AKT and Wnt/ß-catenin pathway.
Neoplasm Metastasis
Cytotoxicity of natural extract from Tegillarca granosa on ovarian cancer cells is mediated by multiple molecules.
Neoplasm Metastasis
Effect of homeopathic treatment on gene expression in Copenhagen rat tumor tissues.
Neoplasm Metastasis
Effects of aurothiomalate treatment on canine osteosarcoma in a murine xenograft model.
Neoplasm Metastasis
Effects of polyamine depletion by alpha-difluoromethylornithine on in vitro and in vivo biological properties of 4T1 murine mammary cancer cells.
Neoplasm Metastasis
EGCG inhibits growth, invasion, angiogenesis and metastasis of pancreatic cancer.
Neoplasm Metastasis
Elevated cleaved caspase-3 is associated with shortened overall survival in several cancer types.
Neoplasm Metastasis
Expression of caspase-3 and hypoxia inducible factor 1? in hepatocellular carcinoma complicated by hemorrhage and necrosis.
Neoplasm Metastasis
Expression of cIAP-1 correlates with nodal metastasis in squamous cell carcinoma of the tongue.
Neoplasm Metastasis
Expression of Fas ligand and caspase-3 contributes to formation of immune escape in gastric cancer.
Neoplasm Metastasis
Expression of PTEN and Caspase-3 and their clinicopathological significance in primary gastric malignant lymphoma.
Neoplasm Metastasis
Expression of SIRT1 and apoptosis-related proteins is predictive for lymph node metastasis and disease-free survival in luminal A breast cancer.
Neoplasm Metastasis
Expression of survivin, cyclinD1, p21(WAF1), caspase-3 in cervical cancer and its relation with prognosis.
Neoplasm Metastasis
Fenton-reaction-stimulative nanoparticles decorated with a reactive-oxygen-species (ROS)-responsive molecular switch for ROS amplification and triple negative breast cancer therapy.
Neoplasm Metastasis
Fluorescence lifetime imaging microscopy of chemotherapy-induced apoptosis resistance in a syngenic mouse tumor model.
Neoplasm Metastasis
Fragment N2, a caspase-3-generated RasGAP fragment, inhibits breast cancer metastatic progression.
Neoplasm Metastasis
FRMD4A upregulation in human squamous cell carcinoma promotes tumor growth and metastasis and is associated with poor prognosis.
Neoplasm Metastasis
Fructooligosaccharides and wheat bran fed at similar fermentation levels differentially affect the expression of genes involved in transport, signaling, apoptosis, cell proliferation, and oncogenesis in the colon epithelia of healthy Fischer 344 rats.
Neoplasm Metastasis
Garcinol Inhibits Cell Proliferation and Promotes Apoptosis in Pancreatic Adenocarcinoma Cells.
Neoplasm Metastasis
Identification of potential prognostic markers for vulvar cancer using immunohistochemical staining of tissue microarrays.
Neoplasm Metastasis
Intake of grape-derived polyphenols reduces C26 tumor growth by inhibiting angiogenesis and inducing apoptosis.
Neoplasm Metastasis
Interleukin-1beta and Caspase-3 expression serve as independent prognostic markers for metastasis and survival in oral squamous cell carcinoma.
Neoplasm Metastasis
In vivo and in vitro inhibition of human gastric cancer progress by upregulating Kank1 gene.
Neoplasm Metastasis
Kallistatin Inhibits Anoikis Resistance and Metastasis of Ectopic Endometrium Cells by Modulating MnSOD and Caspase 3 Signaling.
Neoplasm Metastasis
Knockdown of Livin inhibits growth and invasion of gastric cancer cells through blockade of the MAPK pathway in vitro and in vivo.
Neoplasm Metastasis
Loss of RUNX3 expression significantly affects the clinical outcome of gastric cancer patients and its restoration causes drastic suppression of tumor growth and metastasis.
Neoplasm Metastasis
Mapping Complex Traits in a Diversity Outbred F1 Mouse Population Identifies Germline Modifiers of Metastasis in Human Prostate Cancer.
Neoplasm Metastasis
Melatonin maximizes the therapeutic potential of non-preconditioned MSCs in a DEN-induced rat model of HCC.
Neoplasm Metastasis
Microenvironment effects on promoting upregulation of matrix metalloproteinases in Bcl-2-overexpressing renal cell carcinoma as a response to doxorubicin treatment inducing the production of metastasis.
Neoplasm Metastasis
MicroRNA-421 regulated by HIF-1? promotes metastasis, inhibits apoptosis, and induces cisplatin resistance by targeting E-cadherin and caspase-3 in gastric cancer.
Neoplasm Metastasis
MiR-106a-5p promotes 5-FU resistance and the metastasis of colorectal cancer by targeting TGF?R2.
Neoplasm Metastasis
Monocyte chemoattractant protein-1 modulates invasion and apoptosis of PC-3M prostate cancer cells via regulating expression of VEGF, MMP9 and caspase-3.
Neoplasm Metastasis
Nuclear androgen receptor staining in bone metastases is related to a poor outcome in prostate cancer patients.
Neoplasm Metastasis
Oxysophocarpine Retards the Growth and Metastasis of Oral Squamous Cell Carcinoma by Targeting the Nrf2/HO-1 Axis.
Neoplasm Metastasis
P53 mutation analysis of colorectal liver metastases: relation to actual survival, angiogenic status, and p53 overexpression.
Neoplasm Metastasis
Paeoniflorin, a Natural Product With Multiple Targets in Liver Diseases-A Mini Review.
Neoplasm Metastasis
Protective effect of propofol on hydrogen peroxide-induced human esophageal carcinoma via blocking the Wnt/?-catenin signaling pathway.
Neoplasm Metastasis
Protein expression differences between lung adenocarcinoma and squamous cell carcinoma with brain metastasis.
Neoplasm Metastasis
Rapid Induction of Lung Adenocarcinoma by Fibroblast Growth Factor 9 Signaling through FGF Receptor 3.
Neoplasm Metastasis
Reduction of TIP30 correlates with poor prognosis of gastric cancer patients and its restoration drastically inhibits tumor growth and metastasis.
Neoplasm Metastasis
Relationship between the expression of caspase-3 and the clinical outcome of patients with non-small cell lung cancer.
Neoplasm Metastasis
Scabraside D Derived from Sea Cucumber Induces Apoptosis and Inhibits Metastasis via iNOS and STAT-3 Expression in Human Cholangiocarcinoma Xenografts.
Neoplasm Metastasis
Selective Killing of Hypoxia-Inducible Factor-1-Active Cells Improves Survival in a Mouse Model of Invasive and Metastatic Pancreatic Cancer.
Neoplasm Metastasis
Significance of survivin, caspase-3, and VEGF expression in thyroid carcinoma.
Neoplasm Metastasis
Single-cell analysis reveals metastatic cell heterogeneity in clear cell renal cell carcinoma.
Neoplasm Metastasis
Sphere formation reverses the metastatic and cancer stem cell phenotype of the murine mammary tumour 4T1, independently of the putative cancer stem cell marker Sca-1.
Neoplasm Metastasis
The down-regulated ING5 expression in lung cancer: A potential target of gene therapy.
Neoplasm Metastasis
The promising effects of BMP2 transfected mesenchymal stem cells on human osteosarcoma.
Neoplasm Metastasis
The steroid receptor coactivator-3 is a tumor promoter in a mouse model of thyroid cancer.
Neoplasm Metastasis
Upregulation of ARHGAP30 attenuates pancreatic cancer progression by inactivating the ?-catenin pathway.
Neoplasm Metastasis
Upregulation of SATB1 is associated with the development and progression of glioma.
Neoplasm Metastasis
[Expression and significance of PCNA and Caspase-3 in the tissue of lung cancer]
Neoplasm Metastasis
[Expressions of Bcl-xl and caspase-3 in the prostate cancer tissue and their correlation].
Neoplasm Metastasis
[Impact of preoperative drug therapy on the expression of apoptosis markers in colorectal liver metastases].
Neoplasm Metastasis
[Roles of cyclooxygenase-2 and caspase-3 expression in pathogenesis of lung carcinoma: an experiment with rats]
Neoplasm, Residual
Inhibiting cycloxygenase and ornithine decarboxylase by diclofenac and alpha-difluoromethylornithine blocks cutaneous SCCs by targeting Akt-ERK axis.
Neoplasm, Residual
Percutaneous ethanol injection enhanced the efficacy of radiofrequency ablation in the treatment of HCC: an insight into the mechanism of ethanol action.
Neoplasms
"Anti-Inflammatory Effects of Probiotic Lactobacillus paracasi on Ventricles of BALB/C Mice Treated with Ovalbumin".
Neoplasms
(-)-Epigallocatechin Gallate (EGCG) Enhances the Sensitivity of Colorectal Cancer Cells to 5-FU by Inhibiting GRP78/NF-?B/miR-155-5p/MDR1 Pathway.
Neoplasms
(2Alpha,3beta)-2,3-dihydroxyolean-12-en-28-oic acid, a new natural triterpene from Olea europea, induces caspase dependent apoptosis selectively in colon adenocarcinoma cells.
Neoplasms
(9R)-9-Hydroxystearate-Functionalized Hydroxyapatite as Antiproliferative and Cytotoxic Agent toward Osteosarcoma Cells.
Neoplasms
(S)-10-Hydroxycamptothecin Inhibits Esophageal Squamous Cell Carcinoma Growth In Vitro and In Vivo Via Decreasing Topoisomerase I Enzyme Activity.
Neoplasms
1,2,3-Triazole tethered 1,2,4?trioxane trimer induces apoptosis in metastatic cancer cells and inhibits their proliferation, migration and invasion.
Neoplasms
1,2-Dichloroethane induces cerebellum granular cell apoptosis via mitochondrial pathway in vitro and in vivo.
Neoplasms
1-(2-((Z)-6-(2-(Trifluoromethyl)phenyl)hexa-3-en-1,5-diynyl)phenyl)piperidin-2-one as a new potent apoptosis agent.
Neoplasms
1-[2-(2-Methoxyphenylamino)ethylamino]-3-(naphthalene-1-yloxy)propan-2-ol as a potential anticancer drug.
Neoplasms
10-Dehydrogingerdione ameliorates renal endoplasmic reticulum/oxidative stress and apoptosis in alcoholic nephropathy induced in experimental rats.
Neoplasms
13 Cis-retinoic acid mediates apoptosis in Dalton's lymphoma ascites cells by regulating gene expression.
Neoplasms
2-APCAs, the Novel Microtubule Targeting Agents Active Against Distinct Cancer Cell Lines.
Neoplasms
20(S)-protopanaxadiol regio-selectively targets androgen receptor: anticancer effects in castration-resistant prostate tumors.
Neoplasms
3EZ, 20Ac-ingenol-induced Apoptosis in Chemoresistant Cancers With Cyclin D1 Accumulation.
Neoplasms
4-Nitrobenzylidene malononitrile reduces apoptosis-mediated liver injury in mice.
Neoplasms
5-Fluorouracil induced Fas upregulation associated with apoptosis in liver metastases of colorectal cancer patients.
Neoplasms
5-lipoxygenase deficiency reduces hepatic inflammation and tumor necrosis factor alpha-induced hepatocyte damage in hyperlipidemia-prone ApoE-null mice.
Neoplasms
5-Methyl phenazine-1-carboxylic acid: A novel bioactive metabolite by a rhizosphere soil bacterium that exhibits potent antimicrobial and anticancer activities.
Neoplasms
6-Shogaol induces apoptosis in human hepatocellular carcinoma cells and exhibits anti-tumor activity in vivo through endoplasmic reticulum stress.
Neoplasms
9-cis retinoic acid inhibits cumulus cell apoptosis during the maturation of bovine cumulus-oocyte-complexes.
Neoplasms
?-Carboline derivative TJY-16 inhibits tumor growth by inducing G2/M cell cycle arrest in glioma cells.
Neoplasms
?-Carotene synergistically enhances the anti-tumor effect of 5-Fluorouracil on esophageal squamous cell carcinoma in vivo and in vitro.
Neoplasms
?-Caryophyllene, a Compound Isolated from the Biblical Balm of Gilead (Commiphora gileadensis), Is a Selective Apoptosis Inducer for Tumor Cell Lines.
Neoplasms
?-Cyano-4-hydroxycinnamate induces apoptosis in Dalton's lymphoma cells: role of altered cell survival-regulatory mechanisms.
Neoplasms
?-Elemene inhibits 7,12-dimethylbenz(a)anthracene/12-O-tetradecanoylphorbol-13-acetate-induced skin tumorigenesis through suppression of NF-?B-associated signaling events in the mouse skin model.
Neoplasms
?-Hydroxybutyrate exacerbates lipopolysaccharide/ d-galactosamine-induced inflammatory response and hepatocyte apoptosis in mice.
Neoplasms
?-Ionone derived apoptosis inducing endoperoxides; Discovery of potent leads for anticancer agents.
Neoplasms
?-LAPachone is renoprotective in streptozotocin-induced diabetic mice via regulating the PI3K/Akt/mTOR signaling pathway.
Neoplasms
?-Linolenic Acid Reduces TNF-Induced Apoptosis in C2C12 Myoblasts by Regulating Expression of Apoptotic Proteins.
Neoplasms
?-Mangostin inhibits DMBA/TPA-induced skin cancer through inhibiting inflammation and promoting autophagy and apoptosis by regulating PI3K/Akt/mTOR signaling pathway in mice.
Neoplasms
?-Tocotrienol treatment is more effective against hypoxic tumor cells than normoxic cells: potential implications for cancer therapy.
Neoplasms
?7 nicotinic acetylcholine receptor agonist attenuates the cerebral injury in a rat model of cardiopulmonary bypass by activating the Akt/GSK3? pathway.
Neoplasms
A caspase-3 'death-switch' in colorectal cancer cells for induced and synchronous tumor apoptosis in vitro and in vivo facilitates the development of minimally invasive cell death biomarkers.
Neoplasms
A caspase-3 activatable photoacoustic probe for in vivo imaging of tumor apoptosis.
Neoplasms
A combination hybrid-based vaccination/adoptive cellular therapy to prevent tumor growth by involvement of T cells.
Neoplasms
A comparative anticancer study on procyanidin C1 against receptor positive and receptor negative breast cancer.
Neoplasms
A Comparative Study of Single and Dual Perfusion During End-ischemic Subnormothermic Liver Machine Preservation.
Neoplasms
A comparative study: the prospective influence of nanovectors in leveraging the chemopreventive potential of COX-2 inhibitors against skin cancer.
Neoplasms
A comprehensive review on the anti-cancer properties and mechanisms of action of sesamin, a lignan in sesame seeds (Sesamum indicum).
Neoplasms
A crystalline compound (BM-ANF1) from the Indian toad (Bufo melanostictus, Schneider) skin extract, induced antiproliferation and apoptosis in leukemic and hepatoma cell line involving cell cycle proteins.
Neoplasms
A dermatan sulfate-functionalized biomimetic nanocarrier for melanoma targeted chemotherapy.
Neoplasms
A DM1-doped porous gold nanoshell system for NIR accelerated redox-responsive release and triple modal imaging guided photothermal synergistic chemotherapy.
Neoplasms
A dry extract of Phyllanthus niruri protects normal cells and induces apoptosis in human liver carcinoma cells.
Neoplasms
A First-in-Human Study of Conatumumab in Adult Patients With Advanced Solid Tumors.
Neoplasms
A flavonoid component from Docynia delavayi (Franch.) Schneid represses transplanted H22 hepatoma growth and exhibits low toxic effect on tumor-bearing mice.
Neoplasms
A functional variant at the miR-885-5p binding site of CASP3 confers risk of both index and second primary malignancies in patients with head and neck cancer.
Neoplasms
A Histopathologic and Immunohistochemical Study on Liquification of Human Adipose Tissue Ex Vivo.
Neoplasms
A Homogeneous Polysaccharide from Fructus Schisandra chinensis (Turz.) Baill Induces Mitochondrial Apoptosis through the Hsp90/AKT Signalling Pathway in HepG2 Cells.
Neoplasms
A lactoferrin-derived peptide with cationic residues concentrated in a region of its helical structure induces necrotic cell death in a leukemic cell line (HL-60).
Neoplasms
A methoxyflavanone derivative from the Asian medicinal herb (Perilla frutescens) induces p53-mediated G2/M cell cycle arrest and apoptosis in A549 human lung adenocarcinoma.
Neoplasms
A molecular survey of programmed cell death in rainbow trout: Structural and functional specifications of apoptotic key molecules.
Neoplasms
A more aggressive breast cancer spheroid model coupled to an electronic capillary sensor system for a high-content screening of cytotoxic agents in cancer therapy: 3-dimensional in vitro tumor spheroids as a screening model.
Neoplasms
A Morphological and Molecular Characterization of the Spinal Cord after Ventral Root Avulsion or Distal Peripheral Nerve Axotomy Injuries in Adult Rats.
Neoplasms
A multifunctional polymeric nanotheranostic system delivers doxorubicin and imaging agents across the blood-brain barrier targeting brain metastases of breast cancer.
Neoplasms
A multiple marker analysis of apoptosis-associated protein expression in non-small cell lung cancer in a Chinese population.
Neoplasms
A network pharmacology study on the Tripteryguim wilfordii Hook for treatment of Crohn's disease.
Neoplasms
A new acetylacetone derivative inhibits breast cancer by apoptosis induction and angiogenesis inhibition.
Neoplasms
A new anticancer toxin based on HER2/neu-specific DARPin and photoactive flavoprotein miniSOG.
Neoplasms
A non-apoptotic function of caspase-3 in pharmacologically-induced differentiation of K562 cells.
Neoplasms
A novel cycloheptapeptide exerts strong anticancer activity via stimulation of multiple apoptotic pathways in caspase-3 deficient cancer cells.
Neoplasms
A novel diterpene suppresses CWR22Rv1 tumor growth in vivo through antiproliferation and proapoptosis.
Neoplasms
A novel evodiamine amino derivative as a PI3K/AKT signaling pathway modulator that induces apoptosis in small cell lung cancer cells.
Neoplasms
A novel human ex vivo model for the analysis of molecular events during lung cancer chemotherapy.
Neoplasms
A novel kefir product (PFT) inhibits Ehrlich ascites carcinoma in mice via induction of apoptosis and immunomodulation.
Neoplasms
A novel nanocomposite based on fluorescent turn-on gold nanostars for near-infrared photothermal therapy and self-theranostic caspase-3 imaging of glioblastoma tumor cell.
Neoplasms
A Novel Role of SIRT1/ FGF-21 in Taurine Protection Against Cafeteria Diet-Induced Steatohepatitis in Rats.
Neoplasms
A novel small molecule, LLL12, inhibits STAT3 phosphorylation and activities and exhibits potent growth-suppressive activity in human cancer cells.
Neoplasms
A novel small-molecule activator of procaspase-3 induces apoptosis in cancer cells and reduces tumor growth in human breast, liver and gallbladder cancer xenografts.
Neoplasms
A novel synthetic compound, 3-amino-3-(4-fluoro-phenyl)-1H-quinoline-2,4-dione, inhibits cisplatin-induced hearing loss by the suppression of reactive oxygen species: In vitro and in vivo study.
Neoplasms
A novel synthetic derivative of the natural product berbamine inhibits cell viability and induces apoptosis of human osteosarcoma cells, associated with activation of JNK/AP-1 signaling.
Neoplasms
A peptide with three hyaluronan binding motifs inhibits tumor growth and induces apoptosis.
Neoplasms
A Peptide-Based Positron Emission Tomography Probe for In Vivo Detection of Caspase Activity in Apoptotic Cells.
Neoplasms
A Phase 2 Cancer Chemoprevention Biomarker Trial of Isoflavone G-2535 (Genistein) in Presurgical Bladder Cancer Patients.
Neoplasms
A Photoacoustic Probe for the Imaging of Tumor Apoptosis by Caspase-Mediated Macrocyclization and Self-Assembly.
Neoplasms
A phthalimide derivative that inhibits centrosomal clustering is effective on multiple myeloma.
Neoplasms
A pilot window-of-opportunity study of preoperative fluvastatin in localized prostate cancer.
Neoplasms
A plant-based medicinal food inhibits the growth of human gastric carcinoma by reversing epithelial-mesenchymal transition via the canonical Wnt/?-catenin signaling pathway.
Neoplasms
A polymorphism in JMJD2C alters the cleavage by caspase-3 and the prognosis of human breast cancer.
Neoplasms
A polysaccharide from Trametes robiniophila inhibits human osteosarcoma xenograft tumor growth in vivo.
Neoplasms
A porphyrin photosensitized metal-organic framework for cancer cell apoptosis and caspase responsive theranostics.
Neoplasms
A Preclinical Assessment of Early Continuous Passive Motion and Treadmill Therapeutic Exercises for Generating Chondroprotective Effects After Anterior Cruciate Ligament Rupture.
Neoplasms
A proof of principle clinical trial to determine whether conjugated linoleic acid modulates the lipogenic pathway in human breast cancer tissue.
Neoplasms
A protective effect after clearance of orthotopic rat hepatocellular carcinoma by nanosecond pulsed electric fields.
Neoplasms
A short caspase-3 isoform inhibits chemotherapy-induced apoptosis by blocking apoptosome assembly.
Neoplasms
A small molecule Focal Adhesion Kinase (FAK) inhibitor, targeting Y397 site: 1-(2-Hydroxyethyl) -3, 5, 7-triaza-1-azoniatricyclo [3.3.1.13,7]decane; bromide effectively inhibits FAK autophosphorylation activity and decreases cancer cell viability, clonogenicity and tumor growth in vivo.
Neoplasms
A switch-on molecular biosensor for detection of caspase-3 and imaging of apoptosis of cells.
Neoplasms
A synthetic-lethality RNAi screen reveals an ERK-mTOR co-targeting pro-apoptotic switch in PIK3CA+ oral cancers.
Neoplasms
A systems pathology model for predicting overall survival in patients with refractory, advanced non-small-cell lung cancer treated with gefitinib.
Neoplasms
A tetravalent single chain diabody (CD40/HER2) efficiently inhibits tumor proliferation through recruitment of T cells and anti-HER2 functions.
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A Therapeutic Insight of Niacin and Coenzyme Q10 Against Diabetic Encephalopathy in Rats.
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A WKYMVm-containing combination elicits potent anti-tumor activity in heterotopic cancer animal model.
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A-kinase anchor protein 4 (AKAP4) a promising therapeutic target of colorectal cancer.
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a-Tocopherol modifies the expression of genes related to oxidative stress and apoptosis during invitro maturation and enhances the developmental competence of rabbit oocytes.
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Aberrant expression of OX1 receptors for orexins in colon cancers and liver metastases : an openable gate to apoptosis.
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Abrus agglutinin inhibits oral carcinogenesis through inactivation of NRF2 signaling pathway.
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Absence of caspase 3 activation in neoplastic cells of nasopharyngeal carcinoma biopsies predicts rapid fatal outcome.
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Absence of Caspase-3 Protects Pancreatic {beta}-Cells from c-Myc-induced Apoptosis without Leading to Tumor Formation.
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ABT-263 and rapamycin act cooperatively to kill lymphoma cells in vitro and in vivo.
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ABT-263 induces G1/G0-phase arrest, apoptosis and autophagy in human esophageal cancer cells in vitro.
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Acceleration of pancreatic tumorigenesis under immunosuppressive microenvironment induced by Reg3g overexpression.
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Acetylshikonin isolated from Lithospermum erythrorhizon roots inhibits dihydrofolate reductase and hampers autochthonous mammary carcinogenesis in ?16HER2 transgenic mice.
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Achillea millefolium alleviates testicular damage in paclitaxel-intoxicated rats via attenuation of testicular oxido-inflammatory stress and apoptotic responses.
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Acrylamide exposure aggravates the development of ulcerative colitis in mice through activation of NF-?B, inflammatory cytokines, iNOS, and oxidative stress.
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Acteoside attenuates TSLP-induced mast cell proliferation via down-regulating MDM2.
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Actin-sequestering protein, thymosin-beta-4 (TB4), inhibits caspase-3 activation in paclitaxel-induced tumor cell death.
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Activatable Molecular Systems Using Homologous Near-Infrared Fluorescent Probes for Monitoring Enzyme Activities in Vitro, in Cellulo, and in Vivo.
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Activatable molecular systems using homologous near-infrared fluorescent probes for monitoring enzyme activities in vitro, in cellulo, and in vivo.
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Activated Caspase 3 Expression in Remnant Disease After Neoadjuvant Chemotherapy May Predict Outcomes of Breast Cancer Patients.
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Activated protein C blocks p53-mediated apoptosis in ischemic human brain endothelium and is neuroprotective.
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Activation of actin-cleavable interleukin 1beta-converting enzyme (ICE) family protease CPP-32 during chemotherapeutic agent-induced apoptosis in ovarian carcinoma cells.
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Activation of apoptosis by 1-hydroxy-5,7-dimethoxy-2-naphthalene-carboxaldehyde, a novel compound from Aegle marmelos.
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Activation of apoptosis by rationally constructing NIR amphiphilic AIEgens: surmounting the shackle of mitochondrial membrane potential for amplified tumor ablation.
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Activation of Caspase-3 by Terpenoids and Flavonoids in Different Types of Cancer Cells.
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Activation of caspase-8 by tumour necrosis factor receptor 1 is necessary for caspase-3 activation and apoptosis in oxygen-glucose deprived cultured cortical cells.
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Activation of Multiple Molecular Mechanisms for Increasing Apoptosis in Human Glioblastoma T98G Xenograft.
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Activation of P2X(7)-mediated apoptosis Inhibits DMBA/TPA-induced formation of skin papillomas and cancer in mice.
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Activation of the CPP32 apoptotic protease by distinct signaling pathways with differential sensitivity to Bcl-xL.
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Active caspase 3 and DNA fragmentation as markers for apoptotic cell death in primary and metastatic liver tumours.
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Activity of the hypoxia-activated pro-drug TH-302 in hypoxic and perivascular regions of solid tumors and its potential to enhance therapeutic effects of chemotherapy.
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Acute tumour response to the MEK1/2 inhibitor selumetinib (AZD6244, ARRY-142886) evaluated by non-invasive diffusion-weighted MRI.
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Adeno-associated virus-mediated gene transfer of a secreted form of TRAIL inhibits tumor growth and occurrence in an experimental tumor model.
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Adenoviral-mediated interferon alpha overcomes resistance to the interferon protein in various cancer types and has marked bystander effects.
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Adenovirus arming human IL-24 inhibits neuroblastoma cell proliferation in vitro and xenograft tumor growth in vivo.
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Adenovirus-directed expression of dominant negative estrogen receptor induces apoptosis in breast cancer cells and regression of tumors in nude mice.
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Adenovirus-mediated down-regulation of X-linked inhibitor of apoptosis protein inhibits colon cancer.
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Adenovirus-mediated IL-24 confers radiosensitization to human lung adenocarcinoma in vitro and in vivo.
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Adenovirus-mediated ING4 Gene Transfer in Osteosarcoma Suppresses Tumor Growth via Induction of Apoptosis and Inhibition of Tumor Angiogenesis.
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Adenovirus-mediated ING4/PTEN double tumor suppressor gene co-transfer modified by RGD enhances antitumor activity in human nasopharyngeal carcinoma cells.
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Adenovirus-mediated p53 and ING4 gene co?transfer elicits synergistic antitumor effects through enhancement of p53 acetylation in breast cancer.
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Adenovirus-mediated transfer of caspase-3 with Fas ligand induces drastic apoptosis in U-373MG glioma cells.
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Adiponectin deficiency rescues high-fat diet-induced hepatic injury, apoptosis and autophagy loss despite persistent steatosis.
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Adiponectin receptor agonist AdipoRon induces apoptotic cell death and suppresses proliferation in human ovarian cancer cells.
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Adipose tissue biomarkers involved in early resolution of type 2 diabetes after bariatric surgery.
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Administration with hyperoside sensitizes breast cancer cells to paclitaxel by blocking the TLR4 signaling.
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ADP and other metabolites released from Acanthamoeba castellanii lead to human monocytic cell death through apoptosis and stimulate the secretion of proinflammatory cytokines.
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Advanced glycation end products induce the apoptosis of and inflammation in mouse podocytes through CXCL9-mediated JAK2/STAT3 pathway activation.
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Adzuki bean ameliorates hepatic lipogenesis and proinflammatory mediator expression in mice fed a high-cholesterol and high-fat diet to induce nonalcoholic fatty liver disease.
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Aerosolized 3-bromopyruvate inhibits lung tumorigenesis without causing liver toxicity.
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Ag/Au bimetallic nanoparticles induce apoptosis in human cancer cell lines via P53, CASPASE-3 and BAX/BCL-2 pathways.
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Ag/Au Bimetallic Nanoparticles Inhibit Tumor Growth and Prevent Metastasis in a Mouse Model.
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Aged Garlic Extract Attenuates Neuronal Injury in a Rat Model of Spinal Cord Ischemia/Reperfusion Injury.
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Aggressive fibromatosis (desmoid tumor) is derived from mesenchymal progenitor cells.
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Aging splenocyte and thymocyte apoptosis is associated with enhanced expression of p53, bax, and caspase-3.
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Agomelatine effects on fat-enriched diet induced neuroinflammation and depression-like behavior in rats.
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AKAP12 induces apoptotic cell death in human fibrosarcoma cells by regulating CDKI-cyclin D1 and caspase-3 activity.
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Akt inhibitor enhances apoptotic effect of carboplatin on human epithelial ovarian carcinoma cell lines.
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Akt kinase activation blocks apoptosis in intestinal epithelial cells by inhibiting caspase-3 after polyamine depletion.
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Alamandine protects against renal ischaemia-reperfusion injury in rats via inhibiting oxidative stress.
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Alantolactone induces cell apoptosis partially through down-regulation of testes-specific protease 50 expression.
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Alanyl-glutamine Heals Indomethacin-induced Gastric Ulceration in Rats Via Antisecretory and Anti-apoptotic Mechanisms.
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Albumin-binding caspase-cleavable prodrug that is selectively activated in radiation exposed local tumor.
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Alkylamino Phenol Derivative Induces Apoptosis by Inhibiting EGFR Signaling Pathway in Breast Cancer Cells.
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Allicin induces apoptosis in gastric cancer cells through activation of both extrinsic and intrinsic pathways.
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Allyl Isothiocyanate-Rich Mustard Seed Powder Inhibits Bladder Cancer Growth and Muscle Invasion.
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Aloe-emodin (AE) nanoparticles suppresses proliferation and induces apoptosis in human lung squamous carcinoma via ROS generation in vitro and in vivo.
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Alogliptin abates memory injuries of hepatic encephalopathy induced by acute paracetamol intoxication via switching-off autophagy-related apoptosis.
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Alpha lipoic acid exerts antioxidant effect via Nrf2/HO-1 pathway activation and suppresses hepatic stellate cells activation induced by methotrexate in rats.
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Alpha lipoic acid prevents doxorubicin-induced nephrotoxicity by mitigation of oxidative stress, inflammation, and apoptosis in rats.
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Alpha-fetoprotein antagonizes X-linked inhibitor of apoptosis protein anticaspase activity and disrupts XIAP-caspase interaction.
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Alpha-fetoprotein positively regulates cytochrome c-mediated caspase activation and apoptosome complex formation.
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Alpha-Lipoic Acid Protects Co-Exposure to Lead and Zinc Oxide Nanoparticles Induced Neuro, Immuno and Male Reproductive Toxicity in Rats.
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alphaB-crystallin promotes tumor angiogenesis by increasing vascular survival during tube morphogenesis.
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Alteration of caspase-3 (CPP32/Yama/apopain) in wild-type MCF-7, breast cancer cells.
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Alteration of Proliferation and Apoptotic Markers in Normal and Premalignant Tissue Associated with Prostate Cancer.
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Amelioration of oxidative stress and neuroinflammation in lipopolysaccharide-induced memory impairment using Rosmarinic acid in mice.
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Ameliorative Effect of Graviola (Annona muricata) on Mono Sodium Glutamate-Induced Hepatic Injury in Rats: Antioxidant, Apoptotic, Anti-inflammatory, Lipogenesis Markers, and Histopathological Studies.
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Ameliorative effect of selenium nanoparticles and fish oil on cisplatin and gamma irradiation-induced nephrotoxicity in male albino rats.
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Ameliorative effects of Carica papaya extracts against type II diabetes-induced myocardial pathology and dysfunction in albino rats.
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Ameliorative effects of crocin on paraquat-induced oxidative stress in testis of adult mice: An experimental study.
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Ameliorative Effects of Curcumin on Fibrinogen-Like Protein-2 Gene Expression, Some Oxido-Inflammatory and Apoptotic Markers in a Rat Model of l-Arginine-Induced Acute Pancreatitis.
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Ameliorative effects of pregabalin on LPS induced endothelial and cardiac toxicity.
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Ameliorative effects of sildenafil and/or febuxostat on doxorubicin-induced nephrotoxicity in rats.
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Ameliorative effects of tannic acid on carbon tetrachloride-induced liver fibrosis in vivo and in vitro.
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Ameliorative effects of telmisartan in diabetic rats with indomethacin-induced gastric ulceration.
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Ameliorative effects of thymoquinone against eye lens changes in streptozotocin diabetic rats.
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Ameliorative potential of manganese nanoparticles with low-level ionizing radiation against experimentally induced hepatocarcinogenesis.
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Amentoflavone stimulates apoptosis in B16F-10 melanoma cells by regulating bcl-2, p53 as well as caspase-3 genes and regulates the nitric oxide as well as proinflammatory cytokine production in B16F-10 melanoma cells, tumor associated macrophages and peritoneal macrophages.
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Aminomethylphosphonic acid inhibits growth and metastasis of human prostate cancer in an orthotopic xenograft mouse model.
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AMPK/mTOR-mediated inhibition of survivin partly contributes to metformin-induced apoptosis in human gastric cancer cell.
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An Appraisal of Proliferation and Apoptotic Markers in Papillary Thyroid Carcinoma: An Automated Analysis.
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An Epstein-Barr virus positive natural killer lymphoma xenograft derived for drug testing.
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An ethyl acetate fraction of Artemisia capillaris (ACE-63) induced apoptosis and anti-angiogenesis via inhibition of PI3K/AKT signaling in hepatocellular carcinoma.
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An immunohistochemical evaluation of the proteins Wnt1 and glycogen synthase kinase (GSK)-3? in invasive breast carcinomas.
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An in silico appraisal to identify high affinity anti-apoptotic synthetic tetrapeptide inhibitors targeting the mammalian caspase 3 enzyme.
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An in vitro comparative study with furyl-1,4-quinones endowed with anticancer activities.
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An in vivo anti-tumor effect of eckol from marine brown algae by improving the immune response.
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An injectable depot system for sustained intraperitoneal chemotherapy of ovarian cancer results in favorable drug distribution at the whole body, peritoneal and intratumoral levels.
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An organotin indomethacin derivative inhibits cancer cell proliferation and synergizes the antiproliferative effects of lapatinib in breast cancer cells.
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An RGD-modified MRI-visible polymeric vector for targeted siRNA delivery to hepatocellular carcinoma in nude mice.
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Analysis of caspase activities in rat mammary tumours induced by N-methyl-nitrosourea.
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Analysis of expression of p63 and caspase-3 and their predictive value in patients with squamous cell carcinoma of maxillary sinus.
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Analysis of HGF, MACC1, C-met and apoptosis-related genes in cervical carcinoma mice.
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Analysis of in vivo patterns of caspase 3 gene expression in primary hepatocellular carcinoma and its relationship to p21(WAF1) expression and hepatic apoptosis.
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Analysis of microRNA expression in canine mammary cancer stem-like cells indicates epigenetic regulation of transforming growth factor-beta signaling.
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Analysis of tumor-associated stromal cells using SCID GFP transgenic mice: contribution of local and bone marrow-derived host cells.
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Analyzing the anti-ischemia-reperfusion injury effects of ginsenoside Rb1 mediated through the inhibition of p38? MAPK.
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Androgen deprivation induces senescence characteristics in prostate cancer cells in vitro and in vivo.
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Anti-Alzheimer's Disease Molecular Mechanism of Acori Tatarinowii Rhizoma Based on Network Pharmacology.
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Anti-Amnesic Effect of Walnut via the Regulation of BBB Function and Neuro-Inflammation in A?1-42-Induced Mice.
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Anti-apoptotic and hepatoprotective effects of gomisin A on fulminant hepatic failure induced by D-galactosamine and lipopolysaccharide in mice.
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Anti-apoptotic and pro-survival effect of exercise training on early aged hypertensive rat cerebral cortex.
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Anti-apoptotic and pro-survival effects of exercise training on hypertensive hearts.
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Anti-Cancer Effect of 3-Hydroxy-?-Ionone Identified from Moringa oleifera Lam. Leaf on Human Squamous Cell Carcinoma 15 Cell Line.
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Anti-cancer effect of tectochrysin in NSCLC cells through overexpression of death receptor and inactivation of STAT3.
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Anti-Cancer Effects of Zotarolimus Combined with 5-Fluorouracil Treatment in HCT-116 Colorectal Cancer-Bearing BALB/c Nude Mice.
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Anti-Condyloma acuminata mechanism of microRNAs-375 modulates HPV in cervical cancer cells via the UBE3A and IGF-1R pathway.
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Anti-EMMPRIN antibody treatment of head and neck squamous cell carcinoma in an ex-vivo model.
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Anti-inflammatory and anti-apoptotic effect of combined treatment with methylprednisolone and amniotic membrane mesenchymal stem cells after spinal cord injury in rats.
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Anti-inflammatory effect of delphinidin on intramedullary spinal pressure in a spinal cord injury rat model.
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Anti-inflammatory Role of Mesenchymal Stem Cells in an Acute Lung Injury Mouse Model.
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Anti-inflammatory, antioxidant and anti-apoptotic activity of diosmin in acetic acid-induced ulcerative colitis.
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Anti-Melanoma Activity of Indomethacin Incorporated into Mesoporous Silica Nanoparticles.
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Anti-melanoma effect of ruthenium(II)-diphosphine complexes containing naphthoquinone ligand.
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Anti-neoplastic activity of Amblyomma sculptum, Amblyomma parvum and Rhipicephalus sanguineus tick saliva on breast tumor cell lines.
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Anti-oxidant, anti-apoptotic, anti-hypoxic and anti-inflammatory conditions induced by PTY-2 against STZ-induced stress in islets.
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Anti-oxidative and anti-inflammatory effects of cinnamaldehyde on protecting high glucose-induced damage in cultured dorsal root ganglion neurons of rats.
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Anti-PD-1 therapy redirects macrophages from an M2 to an M1 phenotype inducing regression of OS lung metastases.
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Anti-proliferative and anti-apoptotic effects of grape seed extract on chemo-resistant OVCAR-3 ovarian cancer cells.
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Anti-Proliferative Effect of Copper Oxide Nanorods Against Human Cervical Carcinoma Cells.
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Anti-tumor activity and the mechanism of SIP-S: A sulfated polysaccharide with anti-metastatic effect.
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Anti-tumor Effect of Hedgehog Signaling Inhibitor, Vismodegib, on Castration-resistant Prostate Cancer.
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Anti-tumor effect of hot aqueous extracts from Sonchus oleraceus (L.) L. and Juniperus sabina L - Two traditional medicinal plants in China.
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Anti-tumor effects of atractylenolide I isolated from Atractylodes macrocephala in human lung carcinoma cell lines.
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Anti-Tumor Effects of Ginsenoside 20(S)-Protopanaxadiol and 1,25-Dihydroxyvitamin D3 Combination in Castration Resistant Prostate Cancer.
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Anti-tumor effects of phenolic alkaloids of menispermum dauricum on gastric cancer in vivo and in vitro.
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Anti-tumor effects of progesterone in human glioblastoma multiforme: Role of PI3K/Akt/mTOR signaling.
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Anti-Tumoral Effect of a Celecoxib Low Dose on a Model of Human Medullary Thyroid Cancer In Nude Mice.
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Anti-tumorigenic activity of sophoflavescenol against Lewis lung carcinoma in vitro and in vivo.
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Antiangiogenic and Proapoptotic Activities of Atorvastatin and Ganoderma lucidum in Tumor Mouse Model via VEGF and Caspase-3 Pathways.
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Antiangiogenic and proapoptotic activity of a novel glycoprotein from U. indica is mediated by NF-kappaB and Caspase activated DNase in ascites tumor model.
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Antiangiogenic and proapoptotic effects of dietary restriction on experimental mouse and human brain tumors.
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Antiangiogenic antithrombin induces global changes in the gene expression profile of endothelial cells.
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Antiapoptotic action of carbon monoxide on cultured vascular smooth muscle cells.
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Antiapoptotic effects of estrogen in normal and cancer human cervical epithelial cells.
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Antibody-mediated FOXP3 protein therapy induces apoptosis in cancer cells in vitro and inhibits metastasis in vivo.
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Anticancer Activity a of Caspian Cobra (Naja naja oxiana) snake Venom in Human Cancer Cell Lines Via Induction of Apoptosis.
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Anticancer activity and DNA-binding properties of novel cationic Pt(II) complexes.
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Anticancer activity of bicalutamide-loaded PLGA nanoparticles in prostate cancers.
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Anticancer activity of HS-527, a novel inhibitor targeting PI3-kinase in human pancreatic cancer cells.
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Anticancer activity of recombinant Siva1 protein in human nasopharyngeal carcinoma cell line CNE-2.
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Anticancer activity of sclerotiorin, isolated from an endophytic fungus Cephalotheca faveolata Yaguchi, Nishim. & Udagawa.
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Anticancer activity of tetrandrine by inducing pro-death apoptosis and autophagy in human gastric cancer cells.
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Anticancer and cytotoxic effects of troxerutin on HeLa cell line: an in-vitro model of cervical cancer.
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Anticancer and Radiosensitization Efficacy of Nanocomposite Withania somnifera Extract in Mice Bearing Tumor Cells.
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Anticancer drug 2-methoxyestradiol protects against renal ischemia/reperfusion injury by reducing inflammatory cytokines expression.
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Anticancer Effect of Enterocin A-Colicin E1 Fusion Peptide on the Gastric Cancer Cell.
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Anticancer Effect of Mountain Ginseng on Human Breast Cancer: Comparison with Farm-Cultivated Ginseng.
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Anticancer Efficacy of a Difluorodiarylidenyl Piperidone (HO-3867) in Human Ovarian Cancer Cells and Tumor Xenografts.
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Anticancer mechanisms of doxorubicin and zoledronic acid in breast cancer tumor growth in bone.
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Anticancer targets and mechanisms of calycosin to treat nasopharyngeal carcinoma.
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Antifungal Agent Luliconazole Inhibits the Growth of Mouse Glioma-initiating Cells in Brain Explants.
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Antihyperglycemic potentials of a threatened plant, Helonias dioica: antioxidative stress responses and the signaling cascade.
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Antineoplastic effect of calycosin on osteosarcoma through inducing apoptosis showing in vitro and in vivo investigations.
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Antineoplastic effect of iodine in mammary cancer: participation of 6-iodolactone (6-IL) and peroxisome proliferator-activated receptors (PPAR).
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Antioxidant activity and apoptotic induction as mechanisms of action of Withania somnifera (Ashwagandha) against a hepatocellular carcinoma cell line.
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Antioxidant activity of growth hormone-releasing hormone antagonists in LNCaP human prostate cancer line.
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Antioxidant and antiapoptotic effects of green tea polyphenols against azathioprine-induced liver injury in rats.
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Antioxidant defense of Nrf2 vs pro-inflammatory system of NF-?B during the amoebic liver infection in hamster.
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Antioxidant effect of acetyl-l-carnitine against cisplatin-induced cardiotoxicity.
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Antioxidant effects of Spirulina supplement against lead acetate-induced hepatic injury in rats.
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Antioxidant, anti-inflammatory and anti-apoptotic effects of hydro-ethanolic extract of Cyperus esculentus L. (tigernut) on lead acetate-induced testicular dysfunction in Wistar rats.
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Antioxidant, anti-inflammatory and synergistic anti-hyperglycemic effects of Malaysian propolis and metformin in streptozotocin-induced diabetic rats.
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Antioxidant, Anti-Inflammatory, and Anti-Apoptotic Effects of Azolla pinnata Ethanolic Extract against Lead-Induced Hepatotoxicity in Rats.
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Antioxidative and anti-inflammatory neuroprotective effects of astaxanthin and canthaxanthin in nerve growth factor differentiated PC12 cells.
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Antiproliferative activity and apoptosis-inducing mechanism of constituents from Toona sinensis on human cancer cells.
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Antiproliferative activity of hamigerone and radicinol isolated from Bipolaris papendorfii.
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Antiproliferative and antimigratory activities of bisphosphonates in human breast cancer cell line MCF-7.
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Antiproliferative and apoptosis-inducing activity of Brucea javanica extract on human carcinoma cells.
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Antiproliferative and Apoptotic Effects of Shemamruthaa, a Herbal Preparation, in 7,12-Dimethylbenz(a)Anthracene-Induced Breast Cancer Rats.
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Antiproliferative Effects of Thymoquinone in MCF-7 Breast and HepG2 Liver Cancer Cells: Possible Role of Ceramide and ER Stress.
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Antiproliferative, cytotoxic and apoptotic activity of the bentonite transformation of sesquiterpene lactone glaucolide B to 5?-hydroxy-hirsutinolide on tumor cell lines.
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Antiproliferative, Cytotoxic, and Apoptotic Activity of Steroidal Oximes in Cervicouterine Cell Lines.
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Antitumor Ability of KT2 Peptide Derived from Leukocyte Peptide of Crocodile Against Human HCT116 Colon Cancer Xenografts.
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Antitumor activity of an Artemisia annua herbal preparation and identification of active ingredients.
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Antitumor activity of CKD-602, a camptothecin derivative, in a mouse glioma model.
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Antitumor activity of ginsenoside Rd in gastric cancer via up-regulation of Caspase-3 and Caspase-9.
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Antitumor activity of noscapine in human non-small cell lung cancer xenograft model.
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Antitumor activity of sulforaphane in mice model of skin cancer via blocking sulfatase-2.
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Antitumor alkyl-lysophospholipid analog edelfosine induces apoptosis in pancreatic cancer by targeting endoplasmic reticulum.
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Antitumor and angiostatic activities of the antimicrobial peptide dermaseptin B2.
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Antitumor and radiosensitizing synergistic effects of apigenin and cryptotanshinone against solid Ehrlich carcinoma in female mice.
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Antitumor Effect and Immune Response of Nanosecond Pulsed Electric Fields in Pancreatic Cancer.
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Antitumor effect of a transducible fusogenic peptide releasing multiple proapoptotic peptides by caspase-3.
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Antitumor effect of beta2-microglobulin in leukemic cell-bearing mice via apoptosis-inducing activity: activation of caspase-3 and nuclear factor-kappaB.
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Antitumor effect of TAT-oxygen-dependent degradation-caspase-3 fusion protein specifically stabilized and activated in hypoxic tumor cells.
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Antitumor effects and mechanisms of CpG ODN combined with attenuated Salmonella-delivered siRNAs against PD-1.
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Antitumor Effects and the Compatibility Mechanisms of Herb Pair Scleromitrion diffusum (Willd.) R. J. Wang-Sculellaria barbata D. Don.
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Antitumor effects and the underlying mechanism of licochalcone A combined with 5-fluorouracil in gastric cancer cells.
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Antitumor effects of (32)P-chromic-poly (L-lactide) brachytherapy in nude mice with human prostate cancer.
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Antitumor Effects of Curcumin and Glycyrrhetinic Acid-Modified Curcumin-Loaded Cationic Liposome by Intratumoral Administration.
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Antitumor effects of doxorubicin followed by zoledronic acid in a mouse model of breast cancer.
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Antitumor Effects of Ethanol Extract from Ventilago leiocarpa Benth on Sarcoma 180 Tumor-Bearing Mice and Possible Immune Mechanism.
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Antitumor effects of ginkgolic acid in human cancer cell occur via cell cycle arrest and decrease the Bcl-2/Bax ratio to induce apoptosis.
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Antitumor effects of novel compound, guttiferone K, on colon cancer by p21Waf1/Cip1-mediated G(0) /G(1) cell cycle arrest and apoptosis.
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Antitumor Effects of Trimethylellagic Acid Isolated From Sanguisorba officinalis L. on Colorectal Cancer via Angiogenesis Inhibition and Apoptosis Induction.
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Antitumor Potential of Lippia citriodora Essential Oil in Breast Tumor-Bearing Mice.
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Antitumor properties of Boswellic acid against Ehrlich ascites cells bearing mouse.
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Antitumour activity of Annona squamosa seed extracts is through the generation of free radicals and induction of apoptosis.
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Antiviral interferons induced by Newcastle disease virus (NDV) drive a tumor-selective apoptosis.
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Antrodia cinnamomea induces anti-tumor activity by inhibiting the STAT3 signaling pathway in lung cancer cells.
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APAF-1 is related to an undifferentiated state in the testicular germ cell tumor pathway.
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APE1/Ref-1 regulates STAT3 transcriptional activity and APE1/Ref-1-STAT3 dual-targeting effectively inhibits pancreatic cancer cell survival.
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Apocynin attenuates ischemia-reperfusion lung injury in an isolated and perfused rat lung model.
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Apollon gene silencing induces apoptosis in breast cancer cells through p53 stabilisation and caspase-3 activation.
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APOMAB, a La-specific monoclonal antibody, detects the apoptotic tumor response to life-prolonging and DNA-damaging chemotherapy.
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Apoptin-modified human mesenchymal stem cells inhibit growth of lung carcinoma in nude mice.
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Apoptosis and Caspase 3 Pathway Role on Anti-Proliferative Effects of Scrophulariaoxy Sepala Methanolic Extract on Caco-2 Cells.
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Apoptosis and inactivation of the PI3-kinase pathway by tetrocarcin A in breast cancers.
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Apoptosis Imaging in Oncology by Means of Positron Emission Tomography: A Review.
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Apoptosis in favourable neuroblastomas is not dependent on Fas (CD95/APO-1) expression but on activated caspase 3 (CPP32).
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Apoptosis induced by 1'-acetoxychavicol acetate in Ehrlich ascites tumor cells is associated with modulation of polyamine metabolism and caspase-3 activation.
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Apoptosis induced by ID6105, a new anthracycline (11-hydroxyaclacinomycin X, Hyrubicin), and its anti-tumor effects on experimental tumor models.
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Apoptosis inducing effects of Kuding tea polyphenols in human buccal squamous cell carcinoma cell line BcaCD885.
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Apoptosis induction effect of Apocynum venetum polyphenol on human U87 glioma cells via NF-?B pathway.
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Apoptosis induction in cancer cell lines by the carotenoid Fucoxanthinol from Pseudomonas stutzeri JGI 52.
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Apoptosis induction in lung and prostate cancer cells through silver nanoparticles synthesized from Pinus roxburghii bioactive fraction.
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Apoptosis induction in prostate cancer cells by a novel gene product, pHyde, involves caspase-3.
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Apoptosis induction of poly-S-nitrosated human serum albumin in resistant solid tumor under hypoxia can be restored by phosphodiesterase 5 inhibition.
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Apoptosis is a major cause of so-called "caseous necrosis" in mycobacterial granulomas in HIV-infected patients.
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Apoptosis is signalled early by low doses of ionising radiation in a radiation-induced bystander effect.
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Apoptosis levels increase after castration in the CWR22 human prostate cancer xenograft.
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Apoptosis of human gastric epithelial cells via caspase-3 activation in response to Helicobacter pylori infection: possible involvement of neutrophils through tumor necrosis factor alpha and soluble Fas ligands.
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Apoptosis of human hepatocarcinoma (HepG2) and neuroblastoma (SKN-SH) cells induced by polysaccharides-peptide complexes produced by submerged mycelial culture of an entomopathogenic fungus Cordyceps sphecocephala.
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Apoptosis signal-regulating kinase 1-thioredoxin complex dissociation by capsaicin causes pancreatic tumor growth suppression by inducing apoptosis.
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Apoptosis-inducing peptide loaded in PLGA nanoparticles induces anti-tumor effects in vivo.
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Apoptosis-mediated inhibition of human breast cancer cell proliferation by lemon citrus extract.
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Apoptosis-Related Factors in the Luteal Phase of the Domestic Cat and Their Involvement in the Persistence of Corpora Lutea in Lynx.
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Apoptosis-related Proteins Are Altered by Selective Tyrosine Kinase Inhibitors and Everolimus in HPV-dependent SCC.
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Apoptotic and anti-angiogenic effects of Pulsatilla koreana extract on hepatocellular carcinoma.
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Apoptotic and autophagic cell death induced by glucolaxogenin in cervical cancer cells.
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Apoptotic and proliferative characteristics of proliferation centers in lymph node sections of patients with chronic lymphocytic leukemia.
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Apoptotic caspases inhibit abscopal responses to radiation and identify a new prognostic biomarker for breast cancer patients.
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Apoptotic effect of Biophytum sensitivum on B16F-10 cells and its regulatory effects on nitric oxide and cytokine production on tumor-associated macrophages.
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Apoptotic effects of protocatechuic acid in human breast, lung, liver, cervix, and prostate cancer cells: potential mechanisms of action.
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Apoptotic Effects of Xanthium strumarium via PI3K/AKT/mTOR Pathway in Hepatocellular Carcinoma.
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Apoptotic markers and DNA damage are related to late phase of stroke: Involvement of dyslipidemia and inflammation.
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Apoptotic pathways are selectively activated by granzyme A and/or granzyme B in CTL-mediated target cell lysis.
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Apple procyanidins induce tumor cell apoptosis through mitochondrial pathway activation of caspase-3.
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Applications of daunorubicin-loaded PLGA-PLL-PEG-Tf nanoparticles in hematologic malignancies: an in vitro and in vivo evaluation.
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Aprotinin improves kidney function and decreases tubular cell apoptosis and proapoptotic signaling after renal ischemia-reperfusion.
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Aquaporin-1 inhibition reduces metastatic formation in a mouse model of melanoma.
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Aqueous Extract of Solanum nigrum Leaf Activates Autophagic Cell Death and Enhances Docetaxel-Induced Cytotoxicity in Human Endometrial Carcinoma Cells.
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Arabinoxylan rice bran (MGN-3/Biobran) enhances radiotherapy in animals bearing Ehrlich ascites carcinoma.
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Arctium lappa Root Extract Prevents Lead-Induced Liver Injury by Attenuating Oxidative Stress and Inflammation, and Activating Akt/GSK-3? Signaling.
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Argpyrimidine-modified Heat shock protein 27 in human non-small cell lung cancer: a possible mechanism for evasion of apoptosis.
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Arjunolic acid protects against DNCB-induced atopic dermatitis-like symptoms in mice by restoring a normal cytokine balance.
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Aronia melanocarpa Juice Induces a Redox-Sensitive p73-Related Caspase 3-Dependent Apoptosis in Human Leukemia Cells.
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Arsenic Trioxide Induces Apoptosis of Fibroblast-like Synoviocytes and Represents Antiarthritis Effect in Experimental Model of Rheumatoid Arthritis.
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Arsenic trioxide induces cervical cancer apoptosis, but specifically targets human papillomavirus-infected cell populations.
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Artemisia capillaris extract AC68 induces apoptosis of hepatocellular carcinoma by blocking the PI3K/AKT pathway.
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Artemisiae Iwayomogii Herba Inhibits Growth, Motility, and the PI3K/AKT/mTOR Signaling Pathway in Hepatocellular Carcinoma Cells.
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Artesunate inhibits growth and induces apoptosis in human osteosarcoma HOS cell line in vitro and in vivo.
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Artocarpus altilis (Parkinson) Fosberg Extracts and Geranyl Dihydrochalcone Inhibit STAT3 Activity in Prostate Cancer DU145 Cells.
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AS602801 sensitizes glioma cells to temozolomide and vincristine by blocking gap junction communication between glioma cells and astrocytes.
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Ascorbate potentiates the cytotoxicity of menadione leading to an oxidative stress that kills cancer cells by a non-apoptotic caspase-3 independent form of cell death.
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Ascorbyl stearate and ionizing radiation potentiate apoptosis through intracellular thiols and oxidative stress in murine T lymphoma cells.
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Asialoglycoprotein receptor-magnetic dual targeting nanoparticles for delivery of RASSF1A to hepatocellular carcinoma.
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Asiatic acid induces colon cancer cell growth inhibition and apoptosis through mitochondrial death cascade.
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Aspartate attenuates intestinal injury and inhibits TLR4 and NODs/NF-?B and p38 signaling in weaned pigs after LPS challenge.
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Aspirin Has Antitumor Effects via Expression of Calpain Gene in Cervical Cancer Cells.
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Aspirin inhibits growth of ovarian cancer by upregulating caspase-3 and downregulating bcl-2.
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Assessment of apoptosis by immunohistochemistry to active caspase-3, active caspase-7, or cleaved PARP in monolayer cells and spheroid and subcutaneous xenografts of human carcinoma.
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Assessment of apoptosis in human breast tissue using an antibody against the active form of caspase 3: relation to tumour histopathological characteristics.
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Assessment of drug delivery and anticancer potentials of nanoparticles-loaded siRNA targeting STAT3 in lung cancer, in vitro and in vivo.
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Assessment of Enhanced Thermal Effect Due to Gold Nanoparticles during MR-Guided High-Intensity Focused Ultrasound (HIFU) Procedures Using a Mouse-Tumor Model.
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Assessment of the Inhibitory Effects of Ficin-hydrolyzed Gelatin Derived from Squid (Uroteuthis duvauceli) on Breast Cancer Cell Lines and Animal Model.
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Assessment of the structural reorganization of liver and biochemical parameters of blood serum after introduction of zinc nanoparticles and its oxides.
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Association between CASP3 polymorphisms and overall cancer risk: A meta-analysis of case-control studies.
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Association of active caspase 8 with the mitochondrial membrane during apoptosis: potential roles in cleaving BAP31 and caspase 3 and mediating mitochondrion-endoplasmic reticulum cross talk in etoposide-induced cell death.
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Association of bone loss with the upregulation of survival-related genes and concomitant downregulation of Mammalian target of rapamycin and osteoblast differentiation-related genes in the peripheral blood of late postmenopausal osteoporotic women.
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Association of Casp3 microRNA Target Site (1049216) SNP With the Risk and Progress of Cervical Squamous Cell Carcinoma.
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Association of mitochondrial calpain activation with increased expression and autolysis of calpain small subunit in an early stage of apoptosis.
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Association of TP53 mutation, p53 overexpression, and p53 codon 72 polymorphism with susceptibility to apoptosis in adult patients with diffuse astrocytomas.
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Astaxanthine secured apoptotic death of PC12 cells induced by beta-amyloid peptide 25-35: its molecular action targets.
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Astilbin ameliorates deoxynivalenol-induced oxidative stress and apoptosis in intestinal porcine epithelial cells (IPEC-J2).
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Astragalus Polysaccharide Promotes Adriamycin-Induced Apoptosis in Gastric Cancer Cells.
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Atorvastatin Pretreatment Inhibits Myocardial Inflammation and Apoptosis in Swine After Coronary Microembolization.
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Atractylenolide III induces apoptosis by regulating the Bax/Bcl-2 signaling pathway in human colorectal cancer HCT-116 Cells in vitro and in vivo.
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Attenuating effect of taurine on lipopolysaccharide-induced acute lung injury in hamsters.
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Attenuation effect of polydeoxyribonucleotide on inflammatory cytokines and apoptotic factors induced by particulate matter (PM10) damage in human bronchial cells.
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Attenuation of Aluminum Chloride-Induced Neuroinflammation and Caspase Activation Through the AKT/GSK-3? Pathway by Hesperidin in Wistar Rats.
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Attenuation of cellular toxicity by calpain inhibitor induced by bacterial endotoxin: a mechanistic study using muscle precursor cells as a model system.
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Attenuation of diabetic nephropathy by tocotrienol: involvement of NFkB signaling pathway.
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Attenuation of hyperplasia in lung parenchymal and colonic epithelial cells in DMBA-induced cancer by administering Andrographis paniculata Nees extract using animal model.
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Attenuation of renoinflammatory cascade in experimental model of diabetic nephropathy by sesamol.
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Augmented adriamycin sensitivity in cells transduced with an antisense tumor necrosis factor gene is mediated by caspase-3 downstream from reactive oxygen species.
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Augmentor of liver regeneration ameliorates renal tubular epithelial cell injury after rat liver transplantation.
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Aurora B confers cancer cell resistance to TRAIL-induced apoptosis via phosphorylation of survivin.
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Autologous Bone Marrow Mononuclear Cell Transplantation Delays Progression of Carotid Atherosclerosis in Rabbits.
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Autophagy Induced by Tumor Necrosis Factor ? Mediates Intrinsic Apoptosis in Trophoblastic Cells.
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Autophagy inhibition enhances Matrine derivative MASM induced apoptosis in cancer cells via a mechanism involving reactive oxygen species-mediated PI3K/Akt/mTOR and Erk/p38 signaling.
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Autophagy Inhibition Promotes 5-Fluorouraci-Induced Apoptosis by Stimulating ROS Formation in Human Non-Small Cell Lung Cancer A549 Cells.
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Avicularin reversed multidrug-resistance in human gastric cancer through enhancing Bax and BOK expressions.
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AZD6244 (ARRY-142886), a potent inhibitor of mitogen-activated protein kinase/extracellular signal-regulated kinase kinase 1/2 kinases: mechanism of action in vivo, pharmacokinetic/pharmacodynamic relationship, and potential for combination in preclinical models.
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Azoxystrobin Induces Apoptosis of Human Esophageal Squamous Cell Carcinoma KYSE-150 Cells through Triggering of the Mitochondrial Pathway.
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B7-H4 is Inversely Correlated With T-Cell Infiltration in Clear Cell but Not Serous or Endometrioid Ovarian Cancer.
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Baicalein inhibits tumor progression by inhibiting tumor cell growth and tumor angiogenesis.
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Baicalein Neutralizes Hypercholesterolemia-Induced Aggravation of Oxidative Injury in Rats.
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Baicalin ameliorates isoproterenol-induced acute myocardial infarction through iNOS, inflammation and oxidative stress in rat.
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Baicalin attenuates myocardial ischemia-reperfusion injury through Akt/NF-?B pathway.
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Baicalin protects against zearalenone-induced chicks liver and kidney injury by inhibiting expression of oxidative stress, inflammatory cytokines and caspase signaling pathway.
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Balance between senescence and apoptosis is regulated by telomere damage-induced association between p16 and caspase-3.
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Bamboo salt has in vitro anticancer activity in HCT-116 cells and exerts anti-metastatic effects in vivo.
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Bauhinia variegata candida Fraction Induces Tumor Cell Death by Activation of Caspase-3, RIP, and TNF-R1 and Inhibits Cell Migration and Invasion In Vitro.
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Bax inhibitor-1 overexpression in prelimbic cortex protects rats against depression-like behavior induced by olfactory bulbectomy and reduces apoptotic and inflammatory signals.
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Bcl-2 promotes malignant progression in a PDGF-B-dependent murine model of oligodendroglioma.
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Beetroot red (betanin) inhibits vinyl carbamate- and benzo(a)pyrene-induced lung tumorigenesis through apoptosis.
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Behavioral, histopathological, and biochemical evaluations on the effects of cinnamaldehyde, naloxone, and their combination in morphine-induced cerebellar toxicity.
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Beneficial effects of PTP1B deficiency on brown adipocyte differentiation and protection against apoptosis induced by pro- and anti-inflammatory stimuli.
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Beraprost sodium preconditioning prevents inflammation, apoptosis, and autophagy during hepatic ischemia-reperfusion injury in mice via the P38 and JNK pathways.
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Berbamine inhibited the growth of prostate cancer cells in vivo and in vitro via triggering intrinsic pathway of apoptosis.
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Berbamine suppresses cell proliferation and promotes apoptosis in ovarian cancer partially via the inhibition of Wnt/?-catenin signaling.
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Berberine ameliorates intrahippocampal kainate-induced status epilepticus and consequent epileptogenic process in the rat: Underlying mechanisms.
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Berberine attenuates A?42-induced neuronal damage through regulating circHDAC9/miR-142-5p axis in human neuronal cells.
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Berberine in combination with doxorubicin suppresses growth of murine melanoma B16F10 cells in culture and xenograft.
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Berberine promotes antiproliferative effects of epirubicin in T24 bladder cancer cells by enhancing apoptosis and cell cycle arrest?.
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Bicarbonate transport inhibitor SITS modulates pH homeostasis triggering apoptosis of Dalton's lymphoma: implication of novel molecular mechanisms.
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Bimodal Distribution of Nuclear Factor-?B Activation and Expression of Subunits in Experimental Models of Intracerebral Hemorrhage In Vivo.
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Bioactive Components of Chinese Propolis Water Extract on Antitumor Activity and Quality Control.
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Bioactivities of ethanol extract from the Antarctic freshwater microalga, Chloromonas sp.
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Biobanking of Fresh-Frozen Human Adenocarcinomatous and Normal Colon Tissues: Which Parameters Influence RNA Quality?
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Biochemical modifications and neuronal damage in brain of young and adult rats after long-term exposure to mobile phone radiations.
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Biochemical, pathological and ultrastructural investigation of whether lamotrigine has neuroprotective efficacy against spinal cord ischemia reperfusion injury.
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Biocompatible chitosan-carbon nanocage hybrids for sustained drug release and highly efficient laser and microwave co-irradiation induced cancer therapy.
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Biodegradable Porous Silicon Nanocontainers as an Effective Drug Carrier for Regulation of the Tumor Cell Death Pathways.
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Biodistribution and Efficacy of Low Temperature-Sensitive Liposome Encapsulated Docetaxel Combined with Mild Hyperthermia in a Mouse Model of Prostate Cancer.
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Biodistribution and phototherapeutic properties of Zinc (II) 2,9,16,23-tetrakis (methoxy) phthalocyanine in vivo.
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Biological actions and mechanism of action of calbindin in the process of apoptosis.
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Biological characterization of bovine mammary epithelial cell lines immortalized by HPV16 E6/E7 and SV40T.
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Biological evaluation of a cytotoxic 2-substituted benzimidazole copper(II) complex: DNA damage, antiproliferation and apoptotic induction activity in human cervical cancer cells.
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Biological factors, tumor growth kinetics, and survival after metastasectomy for pulmonary melanoma.
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Biological Potential and Mechanism of Prodigiosin from Serratia marcescens Subsp. lawsoniana in Human Choriocarcinoma and Prostate Cancer Cell Lines.
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Biosynthesized composites of Au-Ag nanoparticles using Trapa peel extract induced ROS-mediated p53 independent apoptosis in cancer cells.
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Bis (Isothiocyanatomethyl) Benzene, A Plant Derived Anti-Neoplastic Compound: Purified from Moringa Oleifera Leaf Extract.
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Bisdemethoxycurcumin attenuates gastric adenocarcinoma growth by inducing mitochondrial dysfunction.
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Bivalent smac mimetics with a diazabicyclic core as highly potent antagonists of XIAP and cIAP1/2 and novel anticancer agents.
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Black tea polyphenols restrict benzopyrene-induced mouse lung cancer progression through inhibition of Cox-2 and induction of caspase-3 expression.
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Blockage of tropomyosin receptor kinase a (TrkA) enhances chemo-sensitivity in breast cancer cells and inhibits metastasis in vivo.
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Blocking circ_0013912 Suppressed Cell Growth, Migration and Invasion of Pancreatic Ductal Adenocarcinoma Cells in vitro and in vivo Partially Through Sponging miR-7-5p.
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Blueberry malvidin-3-galactoside suppresses hepatocellular carcinoma by regulating apoptosis, proliferation, and metastases pathways in vivo and in vitro.
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BMH-21 inhibits viability and induces apoptosis by p53-dependent nucleolar stress responses in SKOV3 ovarian cancer cells.
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Boeravinone B alleviates gut dysbiosis during myocardial infarction-induced cardiotoxicity in rats.
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Bone morphogenetic protein receptor-2 signaling promotes pulmonary arterial endothelial cell survival: implications for loss-of-function mutations in the pathogenesis of pulmonary hypertension.
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Both sunitinib and sorafenib are effective treatments for pheochromocytoma in a xenograft model.
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Botryoid odontogenic cyst. Exploration of proliferative activity, apoptosis and expression of TP53 and BCL2 compared to the histologically identical lateral periodontal and gingival cysts.
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Bovine herpesvirus VP22 induces apoptosis in neuroblastoma cells by upregulating the expression ratio of Bax to Bcl-2.
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Brain-Derived Neurotrophic Factor Levels are Lower in Chronic Stroke Patients: A Relation with Manganese-dependent Superoxide Dismutase ALA16VAL Single Nucleotide Polymorphism through Tumor Necrosis Factor-? and Caspases Pathways.
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BRD4 PROTAC degrader ARV-825 inhibits T-cell acute lymphoblastic leukemia by targeting 'Undruggable' Myc-pathway genes.
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Breast cancer prevention by green tea catechins and black tea theaflavins in the C3(1) SV40 T,t antigen transgenic mouse model is accompanied by increased apoptosis and a decrease in oxidative DNA adducts.
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Breviscapine (BVP) inhibits prostate cancer progression through damaging DNA by minichromosome maintenance protein-7 (MCM-7) modulation.
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Bruton's Tyrosine Kinase Inhibitors Prevent Therapeutic Escape in Breast Cancer Cells.
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Bufalin induces autophagy-mediated cell death in human colon cancer cells through reactive oxygen species generation and JNK activation.
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Bufalin Inhibits HCT116 Colon Cancer Cells and Its Orthotopic Xenograft Tumor in Mice Model through Genes Related to Apoptotic and PTEN/AKT Pathways.
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Butyrate induces apoptosis in murine macrophages via caspase-3, but independent of autocrine synthesis of tumor necrosis factor and nitric oxide.
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C-JUN and CPP32 (CASPASE 3) in human pancreatic cancer: relation to cell proliferation and death.
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C1q/tumor necrosis factor-related protein-6 attenuates TNF-?-induced apoptosis in salivary acinar cells via AMPK/SIRT1-modulated miR-34a-5p expression.
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Cactus pear extracts induce reactive oxygen species production and apoptosis in ovarian cancer cells.
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Cadmium induced inflammation and apoptosis of porcine epididymis via activating RAF1/MEK/ERK and NF-?B pathways.
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CAF-Secreted Annexin A1 Induces Prostate Cancer Cells to Gain Stem Cell-like Features.
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Caffeic acid phenethyl ester suppresses melanoma tumor growth by inhibiting PI3K/AKT/XIAP pathway.
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Caffeine decreases phospho-Chk1 (Ser317) and increases mitotic cells with cyclin B1 and caspase 3 in tumors from UVB-treated mice.
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Caffeine induces apoptosis of osteosarcoma cells by inhibiting AKT/mTOR/S6K, NF-?B and MAPK pathways.
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Calcineurin potentiates the activation of procaspase-3 by accelerating its proteolytic maturation.
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Caloric restriction suppresses microglial activation and prevents neuroapoptosis following cortical injury in rats.
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Camel milk rescues neurotoxic impairments induced by fenpropathrin via regulating oxidative stress, apoptotic, and inflammatory events in the brain of rats.
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Canavanine augments proapoptotic effects of arginine deprivation in cultured human cancer cells.
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Cancer cell survival following DNA damage-mediated premature senescence is regulated by mammalian target of rapamycin (mTOR)-dependent inhibition of sirtuin 1.
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Cancer during pregnancy alters the activity of rat placenta and enhances the expression of cleaved PARP, cytochrome-c and caspase 3.
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Cancer immunoediting from immunosurveillance to tumor escape in microvillus-formed niche: a study of syngeneic orthotopic rat bladder cancer model in comparison with human bladder cancer.
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Cancer stem cell marker phenotypes are reversible and functionally homogeneous in a preclinical model of pancreatic cancer.
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Cannabidiol inhibits human glioma by induction of lethal mitophagy through activating TRPV4.
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Cannabinoid type 2 receptor agonist JWH-133, attenuates Okadaic acid induced spatial memory impairment and neurodegeneration in rats.
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Canola oil inhibits breast cancer cell growth in cultures and in vivo and acts synergistically with chemotherapeutic drugs.
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Carbachol alleviates myocardial injury in septic rats through PI3K/AKT signaling pathway.
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Cardiomyocyte death in patients with end-stage heart failure before and after support with a left ventricular assist device: low incidence of apoptosis despite ubiquitous mediators.
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Cardioprotective Effects of Tannic Acid on Isoproterenol-Induced Myocardial Injury in Rats: Further Insight into 'French Paradox'.
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Cartilage oligomeric matrix protein protects cells against death by elevating members of the IAP family of survival proteins.
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CASP 3 genetic polymorphisms and risk of Hepatocellular carcinoma: a case-control study in a Chinese population.
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CASP8 (rs3834129) and CASP3 (rs4647601) polymorphisms in oropharynx cancer risk, tumor cell differentiation, and prognosis in a cohort of the Brazilian population.
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CASP9 c.-1339A>G and CASP3 c.-1191A>G polymorphisms alter susceptibility and clinical aspects of head and neck squamous cell carcinoma.
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Caspase 1, caspase 3, TNF-alpha, p53, and Hif1-alpha gene expression status of the brain tissues and hippocampal neuron loss in short-term dichlorvos exposed rats.
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Caspase 3 cleavage of the Ste20-related kinase SLK releases and activates an apoptosis-inducing kinase domain and an actin-disassembling region.
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Caspase 3-mediated stimulation of tumor cell repopulation during cancer radiotherapy.
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Caspase-2-induced apoptosis is dependent on caspase-9, but its processing during UV- or tumor necrosis factor-dependent cell death requires caspase-3.
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Caspase-3 activation, Bcl-2 contents, and soluble FAS-ligand are not related to the inflammatory marker profile in patients with sepsis and septic shock.
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Caspase-3 activity, response to chemotherapy and clinical outcome in patients with colon cancer.
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Caspase-3 and inhibitor of apoptosis protein(s) interactions in Saccharomyces cerevisiae and mammalian cells.
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Caspase-3 and survivin expression in pediatric neuroblastoma and their roles in apoptosis.
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Caspase-3 dependent mitotic checkpoint inactivation by the small molecule inducers of mitotic slippage SU6656 and geraldol.
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Caspase-3 enhances lung metastasis and cell migration in a protease-independent mechanism through the ERK pathway.
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Caspase-3 expression in tumorigenesis and prognosis of buccal mucosa squamous cell carcinoma.
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Caspase-3 expression is reduced, in the absence of cleavage, in terminally differentiated normal oral epithelium but is increased in oral squamous cell carcinomas and correlates with tumour stage.
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Caspase-3 immunocytochemical staining for pancreatic islets and pancreatic endocrine tumors.
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Caspase-3 immunohistochemical expression is a marker of apoptosis, increased grade and early recurrence in intracranial meningiomas.
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Caspase-3 inhibits the growth of breast cancer cells independent of protease activity.
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Caspase-3 knockout attenuates radiation-induced tumor repopulation via impairing the ATM/p53/Cox-2/PGE2 pathway in non-small cell lung cancer.
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Caspase-3 probes for PET imaging of apoptotic tumor response to anticancer therapy.
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Caspase-3 Promotes Diabetic Kidney Disease Through Gasdermin E-Mediated Progression to Secondary Necrosis During Apoptosis.
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Caspase-3 regulates the migration, invasion and metastasis of colon cancer cells.
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Caspase-3 status is a determinant of the differential responses to genistein between MDA-MB-231 and MCF-7 breast cancer cells.
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Caspase-3, a key apoptotic protein, as a prognostic marker in gastric cancer after curative surgery.
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Caspase-3, caspase-8, and nuclear factor-kappaB expression in human cholesteatoma.
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Caspase-3-dependent Activation of Calcium-independent Phospholipase A2 Enhances Cell Migration in Non-apoptotic Ovarian Cancer Cells.
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Caspase-3/MAPK pathways as main regulators of the apoptotic effect of the phyto-mediated synthesized silver nanoparticle from dried stem of Eleutherococcus senticosus in human cancer cells.
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Caspase-3: A primary target for natural and synthetic compounds for cancer therapy.
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Caspase-8 and caspase-7 sequentially mediate proteolytic activation of acid sphingomyelinase in TNF-R1 receptosomes.
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Caspase-8 is scarcely silenced and its activity is well correlated with the anticancer effect of tumor necrosis factor-related apoptosis-inducing ligand in gastric cancer cells.
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Cassia tora L. (Jue-ming-zi) has anticancer activity in TCA8113 cells in vitro and exerts anti-metastatic effects in vivo.
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Cationic long-chain ceramide LCL-30 induces cell death by mitochondrial targeting in SW403 cells.
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CBP-Mediated FOXO-1 Acetylation Inhibits Pancreatic Tumor Growth by Targeting SirT.
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CD47 blockade reduces ischemia/reperfusion injury and improves survival in a rat liver transplantation model.
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CDK5 Regulates Paclitaxel Sensitivity in Ovarian Cancer Cells by Modulating AKT Activation, p21Cip1- and p27Kip1-Mediated G1 Cell Cycle Arrest and Apoptosis.
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CDX1 Expression Induced by CagA-Expressing Helicobacter pylori Promotes Gastric Tumorigenesis.
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Celastrol induces the apoptosis of breast cancer cells and inhibits their invasion via downregulation of MMP-9.
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Celecoxib attenuates depressive-like behavior associated with immunological liver injury in C57BL/6 mice through TNF-? and NF-?b dependent mechanisms.
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Celecoxib inhibits growth of tumors in a syngeneic rat liver metastases model for colorectal cancer.
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Celecoxib potentiates the antianxiety and anticompulsive-like activity of fluoxetine against chronic unpredictable mild stress in experimental animals.
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Cell death in MMTV-c-myc transgenic mouse mammary tumors may not be typical apoptosis.
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Cell death induced by cytotoxic CD8+ T cells is immunogenic and primes caspase-3-dependent spread immunity against endogenous tumor antigens.
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Cell death induced by novel procaspase-3 activators can be reduced by growth factors.
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Cell viability assessed in a reproducible model of human osteoblasts derived from human adipose-derived stem cells.
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Cell-in-cell structures are more potent predictors of outcome than senescence or apoptosis in head and neck squamous cell carcinomas.
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Cell-Penetrating Peptide-Modified Gold Nanoparticles for the Delivery of Doxorubicin to Brain Metastatic Breast Cancer.
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Cellular apoptosis susceptibility gene expression in endometrial carcinoma: correlation with Bcl-2, Bax, and caspase-3 expression and outcome.
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Cellular toxicity induced by different pH levels on the R3230AC rat mammary tumour cell line. An in vitro model for investigation of the tumour destructive properties of electrochemical treatment of tumours.
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CF101, an agonist to the A3 adenosine receptor, enhances the chemotherapeutic effect of 5-fluorouracil in a colon carcinoma murine model.
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Changes in Caspase-3, B Cell Leukemia/Lymphoma-2, Interleukin-6, Tumor Necrosis Factor-? and Vascular Endothelial Growth Factor Gene Expression after Human Umbilical Cord Blood Derived Mesenchymal Stem Cells Transfusion in Pulmonary Hypertension Rat Models.
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Characterization and anti-tumor activity of saponin-rich fractions of South Korean sea cucumbers (Apostichopus japonicus).
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Characterization and antitumor activity of novel exopolysaccharide APS of Lactobacillus plantarum WLPL09 from human breast milk.
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Characterization and cytotoxic activity of apoptosis-inducing pierisin-5 protein from white cabbage butterfly.
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Characterization of genomic imbalances in diffuse large B-cell lymphoma by detailed SNP-chip analysis.
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Characterization of spontaneous breast tumor in tree shrews (Tupaia belangeri chinenesis).
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Characterization of the interleukin-1beta-converting enzyme/ced-3-family protease, caspase-3/CPP32, in Hodgkin's disease: lack of caspase-3 expression in nodular lymphocyte predominance Hodgkin's disease.
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Characterization of the Isosteroidal Alkaloid Chuanbeinone from Bulbus of Fritillaria pallidiflora as Novel Antitumor Agent In Vitro and In Vivo.
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Characterization of [(99m)Tc]Duramycin as a SPECT Imaging Agent for Early Assessment of Tumor Apoptosis.
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Characterizing the convergence of protein kinase CK2 and caspase-3 reveals isoform-specific phosphorylation of caspase-3 by CK2?': implications for pathological roles of CK2 in promoting cancer cell survival.
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Charge reversible calcium phosphate lipid hybrid nanoparticle for siRNA delivery.
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Chemoprevention of colorectal cancer by grape seed proanthocyanidin is accompanied by a decrease in proliferation and increase in apoptosis.
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Chemoprevention with Somatuline© Delays the Progression of Pancreatic Neuroendocrine Neoplasms in a Mouse Model of Multiple Endocrine Neoplasia Type 1 (MEN1).
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Chemopreventive Activity of MGN-3/Biobran Against Chemical Induction of Glandular Stomach Carcinogenesis in Rats and Its Apoptotic Effect in Gastric Cancer Cells.
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Chemopreventive and antitumor effects of benzyl isothiocynate on HCC models: A possible role of HGF /pAkt/ STAT3 axis and VEGF.
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Chemopreventive effect of kava on 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone plus benzo[a]pyrene-induced lung tumorigenesis in A/J mice.
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Chemopreventive effect of selenium and Chinese medicinal herbs on N-nitrosobis(2-oxopropyl)amine-induced hepatocellular carcinoma in Syrian hamsters.
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Chemopreventive effect of the non-psychotropic phytocannabinoid cannabidiol on experimental colon cancer.
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Chemopreventive role of arabinoxylan rice bran, MGN-3/Biobran, on liver carcinogenesis in rats.
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Chemotherapy with hybrid liposomes for human breast tumors along with apoptosis in vivo.
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Chemotherapy-induced apoptosis in a transgenic model of neuroblastoma proceeds through p53 induction.
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Chikusetsu Saponin IVa Ameliorates Cerebral Ischemia Reperfusion Injury in Diabetic Mice via Adiponectin-Mediated AMPK/GSK-3? Pathway In Vivo and In Vitro.
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CHIR-258: a potent inhibitor of FLT3 kinase in experimental tumor xenograft models of human acute myelogenous leukemia.
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Chitosan nanoparticles from Artemia salina inhibit progression of hepatocellular carcinoma in vitro and in vivo.
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Chlorella vulgaris or Spirulina platensis mitigate lead acetate-induced testicular oxidative stress and apoptosis with regard to androgen receptor expression in rats.
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Chlorpyrifos induced oxidative stress to promote apoptosis and autophagy through the regulation of miR-19a-AMPK axis in common carp.
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Chondroitin-4-sulphate reduced oxidative injury in caerulein-induced pancreatitis in mice: the involvement of NF-kappaB translocation and apoptosis activation.
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Chromic-P32 phosphate treatment of implanted pancreatic carcinoma: mechanism involved.
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Chronic in vitro exposure to 3'-azido-2', 3'-dideoxythymidine induces senescence and apoptosis and reduces tumorigenicity of metastatic mouse mammary tumor cells.
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Chronic propranolol treatment moderately attenuated development of N-methyl-N-nitrosourea-induced mammary carcinoma in female rats.
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Chronic Stress Exposure Suppresses Mammary Tumor Growth and Reduces Circulating Exosome TGF-? Content via ?-Adrenergic Receptor Signaling in MMTV-PyMT Mice.
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Chronic Unpredictable Mild Stress Accelerates the Growth of Bladder Cancer in a Xenograft Mouse Model.
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Chrysin protects against testicular toxicity caused by lead acetate in rats with its antioxidant, anti-inflammatory, and antiapoptotic properties.
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cIAP2 is highly expressed in Hodgkin-Reed-Sternberg cells and inhibits apoptosis by interfering with constitutively active caspase-3.
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Circadian Clock Protein PERIOD2 Suppresses the PI3K/Akt Pathway and Promotes Cisplatin Sensitivity in Ovarian Cancer.
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circAtp9b knockdown alleviates LPS-caused inflammation provided that microRNA-27a is upregulated.
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Circulating biomarkers of cell death after treatment with the BH-3 mimetic ABT-737 in a preclinical model of small-cell lung cancer.
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Circulating fragmented nucleosomal DNA and caspase-3 mRNA in patients with lymphoma and myeloma.
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CITCO as an Adjuvant Facilitates CHOP-Based Lymphoma Treatment in hCAR-Transgenic Mice.
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Clarithromycin is an effective immunomodulator in experimental pyelonephritis caused by pan-resistant Klebsiella pneumoniae.
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Clarithromycin: immunomodulatory therapy of experimental sepsis and acute pyelonephritis by Escherichia coli.
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Claudins 1, 3, 4, 5 and 7 in esophageal cancer: loss of claudin 3 and 4 expression is associated with metastatic behavior.
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Cleavage of caspases-1, -3, -6, -8 and -9 substrates by proteases in skeletal muscles from mice undergoing cancer cachexia.
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Cleavage of Cdc6 by caspase-3 promotes ATM/ATR kinase-mediated apoptosis of HeLa cells.
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Cleaved caspase-3 immunocytochemical staining for pancreatic islets and pancreatic endocrine tumors: A potential marker for biological malignancy.
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Cleaved Caspase-3 Transcriptionally Regulates Angiogenesis-Promoting Chemotherapy Resistance.
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Cleaved caspase-3, caspase-7 and poly (ADP-ribose) polymerase are complementarily but differentially expressed in human medulloblastomas.
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Clinical significance of caspase-3 expression in pathologic-stage I, nonsmall-cell lung cancer.
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Clinicopathologic differences between 22 cases of CD56-negative and CD56-positive subcutaneous panniculitis-like lymphoma in Japan.
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Clinicopathological significance of caspase-3 and Ki-67 expression in canine mammary gland tumours.
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Clinicopathological significance of PTEN and Caspase-3 expressions in breast cancer.
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Clozapine-induced cardiotoxicity in rats: Involvement of tumour necrosis factor alpha, NF-?? and caspase-3.
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CMTM3, located at the critical tumor suppressor locus 16q22.1, is silenced by CpG methylation in carcinomas and inhibits tumor cell growth through inducing apoptosis.
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CMV increases tubular apoptosis through the TNF-alpha-TNF-R1 pathway in a rat model of chronic renal allograft rejection.
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CNS penetration and pharmacodynamics of the CHK1 inhibitor prexasertib in a mouse Group 3 medulloblastoma model.
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Co-expression of KIT receptor and its ligand stem cell factor in Merkel cell carcinoma.
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Co-localization of PCNA, VCAM-1 and caspase-3 with nestin in xenografts derived from human anaplastic astrocytoma and glioblastoma multiforme tumor spheres.
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Co-targeting of CXCR4 and hedgehog pathways disrupts tumor-stromal crosstalk and improves chemotherapeutic efficacy in pancreatic cancer.
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Co-targeting of endothelin-A and vitamin D receptors: a novel strategy to ameliorate cisplatin-induced nephrotoxicity.
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Coadministration of auraptene and radiotherapy; a novel modality against colon carcinoma cells in vitro and in vivo.
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Coagulation factor Xa drives tumor cells into apoptosis through BH3-only protein Bim up-regulation.
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Coated chitosan nanoparticles encapsulating caspase 3 activator for effective treatment of colorectral cancer.
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Cobalt iron oxide nanoparticles induce cytotoxicity and regulate the apoptotic genes through ROS in human liver cells (HepG2).
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Cod liver oil in sodium nitrite induced hepatic injury: Does it have a potential protective effect?
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Coexistence of Aflatoxicosis with Protein Malnutrition Worsens Hepatic Oxidative Damage in Rats.
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Coexistence of high levels of apoptotic signaling and inhibitor of apoptosis proteins in human tumor cells: implication for cancer specific therapy.
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Cold-Atmospheric Plasma Induces Tumor Cell Death in Preclinical In Vivo and In Vitro Models of Human Cholangiocarcinoma.
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Combination of adenoviral virotherapy and temozolomide chemotherapy eradicates malignant glioma through autophagic and apoptotic cell death in vivo.
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Combination of Caspy2 and IP-10 Gene Therapy Significantly Improves Therapeutic Efficacy Against Murine Malignant Neoplasm Growth and Metastasis.
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Combination of DESI2 and endostatin gene therapy significantly improves antitumor efficacy by accumulating DNA lesions, inducing apoptosis and inhibiting angiogenesis.
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Combination of N-(4-hydroxyphenyl) retinamide and genistein increased apoptosis in neuroblastoma SK-N-BE2 and SH-SY5Y xenografts.
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Combination of oncolytic adenovirus targeting SATB1 and docetaxel for the treatment of castration-resistant prostate cancer.
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Combination of Quercetin and 2-Methoxyestradiol Enhances Inhibition of Human Prostate Cancer LNCaP and PC-3 Cells Xenograft Tumor Growth.
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Combination of quercetin, cinnamaldehyde and hirudin protects rat dorsal root ganglion neurons against high glucose-induced injury through Nrf-2/HO-1 activation and NF-?B inhibition.
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Combination of SL327 and Sunitinib Malate leads to an additive anti-cancer effect in doxorubicin resistant thyroid carcinoma cells.
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Combination of TNF-? and graphene oxide-loaded BEZ235 to enhance apoptosis of PIK3CA mutant colorectal cancer cells.
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Combination therapy inhibits development and progression of mammary tumours in immunocompetent mice.
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Combination therapy with dacarbazine and statins improved the survival rate in mice with metastatic melanoma.
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Combination therapy with human umbilical cord mesenchymal stem cells and angiotensin-converting enzyme 2 is superior for the treatment of acute lung ischemia-reperfusion injury in rats.
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Combination treatment with low-dose Niaspan and tissue plasminogen activator provides neuroprotection after embolic stroke in rats.
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Combination treatment with oxaliplatin and mangiferin causes increased apoptosis and downregulation of NF?B in cancer cell lines.
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Combinatorial effect of curcumin and tumor necrosis factor-?-related apoptosis-inducing ligand (TRAIL) in induction of apoptosis via inhibition of nuclear factor kappa activity and enhancement of caspase-3 activity in chronic myeloid cells: An In-vitro study.
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Combinatorial effect of zoledronic acid and irradiation on the prevention of DMBA-induced precancerogenic changes in the mammary tissues of rats.
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Combinatorial gene targeting hTERT and BI-1 in CNE-2 nasopharyngeal carcinoma cell line.
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Combined application of camptothecin and the guanylate cyclase activator YC-1: Impact on cell death and apoptosis-related proteins in ovarian carcinoma cell lines.
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Combined effects of 17?-estradiol and exercise training on cardiac apoptosis in ovariectomized rats.
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Combined effects of Lenvatinib and iodine-131 on cell apoptosis in nasopharyngeal carcinoma through inducing endoplasmic reticulum stress.
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Combined endostatin and TRAIL gene transfer suppresses human hepatocellular carcinoma growth and angiogenesis in nude mice.
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Combined inhibition of PAK7, MAP3K7 and CK2alpha kinases inhibits the growth of MiaPaCa2 pancreatic cancer cell xenografts.
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Combined modality doxorubicin-based chemotherapy and chitosan-mediated p53 gene therapy using double-walled microspheres for treatment of human hepatocellular carcinoma.
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Combined photodynamic therapy with chloroaluminum phthalocyanine and doxorubicin nanoemulsions in breast cancer model.
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Combined therapy with oncolytic adenoviruses encoding TRAIL and IL-12 genes markedly suppressed human hepatocellular carcinoma both in vitro and in an orthotopic transplanted mouse model.
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Combined treatment with acetazolamide and cisplatin enhances chemosensitivity in laryngeal carcinoma Hep-2 cells.
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Combining kallistatin gene therapy and meloxicam to treat hepatocellular carcinoma in mice.
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Combretastatin A-4 inhibits cell growth and metastasis in bladder cancer cells and retards tumour growth in a murine orthotopic bladder tumour model.
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Comparative cellular and molecular analysis of cytotoxicity and apoptosis induction by doxorubicin and Baneh in human breast cancer T47D cells.
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Comparative cytotoxic response of nickel ferrite nanoparticles in human liver HepG2 and breast MFC-7 cancer cells.
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Comparative cytotoxicity of dolomite nanoparticles in human larynx HEp2 and liver HepG2 cells.
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Comparative Evaluation of Clinical Efficacy and Safety of Collagen Laminin-Based Dermal Matrix Combined With Resveratrol Microparticles (Dermalix) and Standard Wound Care for Diabetic Foot Ulcers.
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Comparative evaluation of PLGA nanoparticle delivery system for 5-fluorouracil and curcumin on squamous cell carcinoma.
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Comparative expression of caspases and annexin V in benign and malignant ovarian tumors.
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Comparing different physical factors on serum TNF-? levels, chondrocyte apoptosis, caspase-3 and caspase-8 expression in osteoarthritis of the knee in rabbits.
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Comparison of ACINUS, caspase-3, and TUNEL as apoptotic markers in determination of tumor growth rates of clinically localized prostate cancer using image analysis.
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Comparison of caspase-3 activation in tumor cells upon treatment of chemotherapeutic drugs using capillary electrophoresis.
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Comparison of responsiveness to cancer development and anti-cancer drug in three different C57BL/6N stocks.
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Comparison of the effect of intravitreal bevacizumab and intravitreal fasudil on retinal VEGF, TNF?, and caspase 3 levels in an experimental diabetes model.
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Comparisons of the anti-tumor activity of polysaccharides from fermented mycelia and cultivated fruiting bodies of Cordyceps militaris in vitro.
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Compound Opening Arrow Mixture exerts anti-tumor effects in a mouse model of breast cancer.
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Compound Radix Sophorae Flavescentis exerts antitumor effects by inhibiting the proliferation and inducing the apoptosis of esophageal carcinoma TE-8 cells.
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Concanavalin A induces apoptosis in a dose-dependent manner by modulating thiol/disulfide homeostasis in C6 glioblastoma cells.
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Conception, synthesis, and characterization of a rofecoxib-combretastatin hybrid drug with potent cyclooxygenase-2 (COX-2) inhibiting and microtubule disrupting activities in colon cancer cell culture and xenograft models.
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Concomitance of downregulated active caspase-3 and upregulated X-chromosome linked inhibitor of apoptosis protein as a sensitive diagnostic approach for breast cancer.
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Conditional disruption of rictor demonstrates a direct requirement for mTORC2 in skin tumor development and continued growth of established tumors.
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Conditionally replicating adenovirus combined with gene-targeted radiotherapy induces apoptosis via TRAIL death receptors in MDA-MB-231 cells.
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Confocal microscopy of the mitochondrial permeability transition in necrotic and apoptotic cell death.
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Connexin-43 downregulation in G2/M phase enriched tumour cells causes extensive low-dose hyper-radiosensitivity (HRS) associated with mitochondrial apoptotic events.
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Constitutive TLR4 signalling in intestinal epithelium reduces tumor load by increasing apoptosis in APC(Min/+) mice.
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Constitutive transgene expression of Stem Cell Antigen-1 in the hair follicle alters the sensitivity to tumor formation and progression.
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Continuous Intraperitoneal Carboplatin Delivery for the Treatment of Late-Stage Ovarian Cancer.
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Contribution of RIP3 and MLKL to immunogenic cell death signaling in cancer chemotherapy.
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Control of apoptosis during angiogenesis by survivin expression in endothelial cells.
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Control of nutrient stress-induced metabolic reprogramming by PKC? in tumorigenesis.
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Controlling joint instability delays the degeneration of articular cartilage in a rat model.
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Convallatoxin, a dual inducer of autophagy and apoptosis, inhibits angiogenesis in vitro and in vivo.
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Copper oxide nanoparticles induced mitochondria mediated apoptosis in human hepatocarcinoma cells.
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Copper-induced tight junction mRNA expression changes, apoptosis and antioxidant responses via NF-?B, TOR and Nrf2 signaling molecules in the gills of fish: preventive role of arginine.
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Cordycepin inhibits cell growth and induces apoptosis in human cholangiocarcinoma.
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Cornel iridoid glycoside inhibits inflammation and apoptosis in brains of rats with focal cerebral ischemia.
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Correlation between responsiveness of neoadjuvant chemotherapy and apoptosis-associated proteins for cervical adenocarcinoma.
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Costunolide induces mitochondria-mediated apoptosis in human gastric adenocarcinoma BGC-823 cells.
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Coumarin Sulfonamides and Amides Derivatives: Design, Synthesis, and Antitumor Activity In Vitro.
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Coupled positive feedbacks provoke slow induction plus fast switching in apoptosis.
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CP-31398 prevents the growth of p53-mutated colorectal cancer cells in vitro and in vivo.
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CP-31398 restores mutant p53 tumor suppressor function and inhibits UVB-induced skin carcinogenesis in mice.
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CpG island promoter hypermethylation of the pro-apoptotic gene caspase-8 is a common hallmark of relapsed glioblastoma multiforme.
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CPP32 expression and its significance in multidrug-resistant tumor cells and their parent cells.
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Cratoxy formosum leaf extract inhibits proliferation and migration of human breast cancer MCF-7 cells.
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Crocin exerts improving effects on indomethacin-induced small intestinal ulcer by antioxidant, anti-inflammatory and anti-apoptotic mechanisms.
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Crocin induces autophagic cell death and inhibits cell invasion of cervical cancer SiHa cells through activation of PI3K/AKT.
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Crocin protects against cardiotoxicity induced by doxorubicin through TLR-2/NF-?B signal pathway in vivo and vitro.
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Crohn's disease-associated ATG16L1 T300A genotype is associated with improved survival in gastric cancer.
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Cross talk between apoptosis and invasion signaling in cancer cells through caspase-3 activation.
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Cross-immunity in Nile tilapia vaccinated with Streptococcus agalactiae and Streptococcus iniae vaccines.
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Crosstalk between Extrinsic and Intrinsic Cell Death Pathways in Pancreatic Cancer: Synergistic Action of Estrogen Metabolite and Ligands of Death Receptor Family.
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CTLA-4 is constitutively expressed on tumor cells and can trigger apoptosis upon ligand interaction.
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Cucurbita ficifolia Fruit Extract Induces Tp53/Caspase-Mediated Apoptosis in MCF-7 Breast Cancer Cells.
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Cucurbitacin B induces apoptosis by inhibition of the JAK/STAT pathway and potentiates antiproliferative effects of gemcitabine on pancreatic cancer cells.
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Cucurbitacins as inducers of cell death and a rich source of potential anticancer compounds.
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Curcumin alleviates colistin-induced nephrotoxicity and neurotoxicity in rats via attenuation of oxidative stress, inflammation and apoptosis.
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Curcumin ameliorates doxorubicin-induced cardiotoxicity by abrogation of inflammation, apoptosis, oxidative DNA damage, and protein oxidation in rats.
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Curcumin ameliorates oxaliplatin-induced chemoresistance in HCT116 colorectal cancer cells in vitro and in vivo.
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Curcumin Attenuates Inflammation, Oxidative Stress, and Ultrastructural Damage Induced by Spinal Cord Ischemia-Reperfusion Injury in Rats.
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Curcumin Combined with Oxaliplatin Effectively Suppress Colorectal Carcinoma in vivo Through Inducing Apoptosis.
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Curcumin induces Apaf-1-dependent, p21-mediated caspase activation and apoptosis.
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Curcumin inhibited the growth and invasion of human monocytic leukaemia SHI-1 cells in vivo by altering MAPK and MMP signalling.
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Curcumin suppresses constitutive activation of STAT-3 by up-regulating protein inhibitor of activated STAT-3 (PIAS-3) in ovarian and endometrial cancer cells.
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Curcumin suppresses gastric cancer by inhibiting gastrin-mediated acid secretion.
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Curcumin-induced apoptosis of human colon cancer colo 205 cells through the production of ROS, Ca2+ and the activation of caspase-3.
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Curcuminoids encapsulated liposome nanoparticles as a blue light emitting diode induced photodynamic therapeutic system for cancer treatment.
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Curcumol inhibits lung adenocarcinoma growth and metastasis via inactivation of PI3K/AKT and Wnt/ß-catenin pathway.
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CXCL8 gene silencing promotes neuroglial cells activation while inhibiting neuroinflammation through the PI3K/Akt/NF-?B-signaling pathway in mice with ischemic stroke.
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CXCR4-gp120-IIIB interactions induce caspase-mediated apoptosis of prostate cancer cells and inhibit tumor growth.
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Cyanocobalamin and/or calcitriol mitigate renal damage-mediated by tamoxifen in rats: Implication of caspase-3/NF-?B signaling pathways.
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Cyclin-dependent kinase inhibitor 3 promotes cancer cell proliferation and tumorigenesis in nasopharyngeal carcinoma by targeting P27.
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Cycling hypoxia induces chemoresistance through the activation of reactive oxygen species-mediated B-cell lymphoma extra-long pathway in glioblastoma multiforme.
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Cyclooxygenase (COX)-1 Activity Precedes the COX-2 Induction in Abeta-Induced Neuroinflammation.
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Cyclooxygenase (COX)-2 and cell cycle activity in a transgenic mouse model of Alzheimer's disease neuropathology.
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Cyclooxygenase-2 protein expression in relation to apoptotic potential and its prognostic significance in bladder urothelial carcinoma.
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Cypermethrin-Induced Nigrostriatal Dopaminergic Neurodegeneration Alters the Mitochondrial Function:A Proteomics Study.
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Cystathionine ?-synthase mediated PRRX2/IL-6/STAT3 inactivation suppresses Tregs infiltration and induces apoptosis to inhibit HCC carcinogenesis.
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Cytochrome c-dependent activation of caspase-3 by tumor necrosis factor requires induction of the mitochondrial permeability transition.
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CytoregR inhibits growth and proliferation of human adenocarcinoma cells via induction of apoptosis.
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Cytostatic/Cytotoxic Effects of 5-Fluorouridine Nucleolipids on Colon, Hepatocellular, and Renal Carcinoma Cells: in vitro Identification of a Potential Cytotoxic Multi-Anticancer Drug.
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Cytotoxic action of acetate on tumor cells of thymic origin: Role of MCT-1, pH homeostasis and altered cell survival regulation.
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Cytotoxic activity of Apomine is due to a novel membrane-mediated cytolytic mechanism independent of apoptosis in the A375 human melanoma cell line.
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Cytotoxic and Apoptotic Activities of Methanolic Subfractions of Scrophularia oxysepala against Human Breast Cancer Cell Line.
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Cytotoxic and apoptotic effects of Ebenus boissieri Barbey on human lung cancer cell line A549.
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Cytotoxic and apoptotic effects of prenylflavonoid artonin B in human acute lymphoblastic leukemia cells.
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Cytotoxic and apoptotic properties of a novel nano-toxin formulation based on biologically synthesized silver nanoparticle loaded with recombinant truncated pseudomonas exotoxin A.
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Cytotoxic and immunomodulatory effects of Ebenus boissieri Barbey on breast cancer cells.
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Cytotoxic Components Against Human Oral Squamous Cell Carcinoma Isolated from Andrographis paniculata.
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Cytotoxic effect of chlorpyrifos is associated with activation of Nrf-2/HO-1 system and inflammatory response in tongue of male Wistar rats.
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Cytotoxic effects, inflammatory response and apoptosis induction of cyclophosphamide in the peripheral blood leukocyte of blunt snout bream (Megalobrama amblycephala).
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Cytotoxic synergy between the multikinase inhibitor sorafenib and the proteasome inhibitor bortezomib in vitro: induction of apoptosis through Akt and c-Jun NH2-terminal kinase pathways.
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Cytotoxicity and pro-apoptosis activity of synthetic 1,3-thiazole incorporated phthalimide derivatives on cancer cells.
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Cytotoxicity and Pro-Apoptotic, Antioxidant and Anti-Inflammatory Activities of Geopropolis Produced by the Stingless Bee Melipona fasciculata Smith.
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Cytotoxicity of a newly synthesized nitroxide derivative of 4-ferrocenecarboxyl-2,2,6,6-tetramethylpiperidine-1-oxyl in high metastatic lung tumor cells.
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Cytotoxicity of natural extract from Tegillarca granosa on ovarian cancer cells is mediated by multiple molecules.
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D-galactosamine-induced mouse hepatic apoptosis: possible involvement with tumor necrosis factor, but not with caspase-3 activity.
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D-pinitol mitigates tumor growth by modulating interleukins and hormones and induces apoptosis in rat breast carcinogenesis through inhibition of NF-?B.
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D-Pinitol treatment induced the apoptosis in human leukemia MOLT-4 cells by improved apoptotic signaling pathway.
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D-Ribose-L-cysteine exhibits adaptogenic-like activity through inhibition of oxido-inflammatory responses and increased neuronal caspase-3 activity in mice exposed to unpredictable chronic mild stress.
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Daidzein ameliorates spinal cord ischemia/reperfusion injury-induced neurological function deficits in Sprague-Dawley rats through PI3K/Akt signaling pathway.
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Daidzein-sulfate metabolites affect transcriptional and antiproliferative activities of estrogen receptor-beta in cultured human cancer cells.
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Daphnane Diterpenoids from Daphne genkwa Inhibit PI3K/Akt/mTOR Signaling and Induce Cell Cycle Arrest and Apoptosis in Human Colon Cancer Cells.
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Dapoxetine attenuates testosterone-induced prostatic hyperplasia in rats by the regulation of inflammatory and apoptotic proteins.
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Dapsone Ameliorates Isoproterenol-Induced Myocardial Infarction via Nrf2/ HO-1; TLR4/ TNF-? Signaling Pathways and the Suppression of Oxidative Stress, Inflammation, and Apoptosis in Rats.
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Darbepoetin-alpha enhances hepatectomy-associated stimulation of colorectal liver metastatic growth.
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Darwinian dynamics of intratumoral heterogeneity: not solely random mutations but also variable environmental selection forces.
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Death by histone deacetylase inhibitor quisinostat in tongue squamous cell carcinoma via apoptosis, pyroptosis, and ferroptosis.
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Deciphering the molecular pathways of apoptosis using purified fractions from leaf extract of Basella alba through studying the regulation of apoptosis related genes.
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Decorin protein core inhibits in vivo cancer growth and metabolism by hindering epidermal growth factor receptor function and triggering apoptosis via caspase-3 activation.
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Decursin from Angelica gigas Nakai Inhibits B16F10 Melanoma Growth Through Induction of Apoptosis.
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Deep brain stimulation induces antiapoptotic and anti-inflammatory effects in epileptic rats.
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Defects at the Posttranscriptional Level Account for the Low TCR? Chain Expression Detected in Gastric Cancer Independently of Caspase-3 Activity.
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Deficiency of caspase 3 in tumor xenograft impairs therapeutic effect of measles virus Edmoston strain.
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Deficits of urothelial cell proliferation, cytoskeleton, and barrier function protein expressions in patients with recurrent and persistent urinary tract infections.
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Defining the Salvage Time Window for the Use of Ischemic Postconditioning in Skeletal Muscle Ischemia Reperfusion Injury.
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Deguelin targets multiple oncogenic signaling pathways to combat human malignancies.
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Dehydroepiandrosterone protects against acetaminophen-induced liver damage in rats by upregulation of Bcl-2 and activation of sirt signalling.
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Delayed anesthetic preconditioning protects against myocardial infarction via activation of nuclear factor-?B and upregulation of autophagy.
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Delayed Cytotoxic Effects of Methyl Jasmonate and cis-Jasmone Induced Apoptosis in Prostate Cancer Cells.
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Delayed growth of glioma by a polysaccharide from Aster tataricus involve upregulation of Bax/Bcl-2 ratio, activation of caspase-3/8/9, and downregulation of the Akt.
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Deletion of Btg1 Induces Prmt1-Dependent Apoptosis and Increased Stemness in Shh-Type Medulloblastoma Cells Without Affecting Tumor Frequency.
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Deletion of cyclooxygenase 2 in mouse mammary epithelial cells delays breast cancer onset through augmentation of type 1 immune responses in tumors.
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Delicaflavone induces apoptosis via mitochondrial pathway accompanying G2/M cycle arrest and inhibition of MAPK signaling cascades in cervical cancer HeLa cells.
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Delicaflavone induces ROS-mediated apoptosis and inhibits PI3K/AKT/mTOR and Ras/MEK/Erk signaling pathways in colorectal cancer cells.
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Delivery of improved oncolytic adenoviruses by mesenchymal stromal cells for elimination of tumorigenic pancreatic cancer cells.
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Delivery of Mixed-Lineage Kinase Domain-Like Protein by Vapor Nanobubble Photoporation Induces Necroptotic-Like Cell Death in Tumor Cells.
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delta-Opioid receptor activation attenuates oxidative injury in the ischemic rat brain.
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Deltonin, a Steroidal Saponin, Inhibits Colon Cancer Cell Growth in Vitro and Tumor Growth in Vivo via Induction of Apoptosis and Antiangiogenesis.
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Deoxynivalenol induced apoptosis and inflammation of IPEC-J2 cells by promoting ROS production.
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Deoxynivalenol induced mouse skin tumor initiation: Elucidation of molecular mechanisms in human HaCaT keratinocytes.
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Depicting Changes in Tumor Biology in Response to Cetuximab Monotherapy or Combination Therapy by Apoptosis and Proliferation Imaging Using 18F-ICMT-11 and 18F-FLT PET.
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Depression of p53-independent Akt survival signals in human oral cancer cells bearing mutated p53 gene after exposure to high-LET radiation.
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Depsipeptide (FR901228) induces histone acetylation and inhibition of histone deacetylase in chronic lymphocytic leukemia cells concurrent with activation of caspase 8-mediated apoptosis and down-regulation of c-FLIP protein.
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Desensitization of the permeability transition pore by cyclosporin a prevents activation of the mitochondrial apoptotic pathway and liver damage by tumor necrosis factor-alpha.
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Design and Synthesis of DNA-Interactive ?-Carboline-Oxindole Hybrids as Cytotoxic and Apoptosis-Inducing Agents.
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Design and Synthesis of Novel Anti-Proliferative Emodin Derivatives and Studies on their Cell Cycle Arrest, Apoptosis Pathway and Migration.
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Design and synthesis of novel N()-substituted thiosemicarbazones bearing a pyrrole unit as potential anticancer agents.
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Design and synthesis of novel tranilast analogs: Docking, antiproliferative evaluation and in-silico screening of TGF?R1 inhibitors.
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Design and validation of an orally administrated active L. fermentum-L. acidophilus probiotic formulation using colorectal cancer Apc (Min/+) mouse model.
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Design, synthesis and antitumor evaluation of new 1,8-naphthalimide derivatives targeting nuclear DNA.
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Design, synthesis and biological evaluation of cinnamic acyl shikonin derivatives.
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Design, synthesis and molecular modeling study of certain VEGFR-2 inhibitors based on thienopyrimidne scaffold as cancer targeting agents.
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Design, synthesis, biological evaluation and molecular modeling studies of 1-aryl-6-(3,4,5-trimethoxyphenyl)-3(Z)-hexen-1,5-diynes as a new class of potent antitumor agents.
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Developing a Powerful In Silico Tool for the Discovery of Novel Caspase-3 Substrates: A Preliminary Screening of the Human Proteome.
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Developing adenoviral vectors encoding therapeutic genes toxic to host cells: comparing binary and single-inducible vectors expressing truncated E2F-1.
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Development and pharmacologic characterization of deoxybromophospha sugar derivatives with antileukemic activity.
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Development of a Cationic Amphiphilic Helical Peptidomimetic (B18L) As A Novel Anti-Cancer Drug Lead.
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Development of a novel azaspirane that targets the Janus kinase-signal transducer and activator of transcription (STAT) pathway in hepatocellular carcinoma in vitro and in vivo.
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Development of an advanced nanoformulation for the intracellular delivery of a caspase-3 selective activity-based probe.
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Development of cisplatin-loaded hydrogels for trans-portal vein chemoembolization in an orthotopic liver cancer mouse model.
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Development of HPLC Method for Quantification of Sinigrin from Raphanus sativus Roots and Evaluation of Its Anticancer Potential.
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Development of immunomodulatory six base-length non-CpG motif oligonucleotides for cancer vaccination.
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Development of novel amino-quinoline-5,8-dione derivatives as NAD(P)H:quinone oxidoreductase 1 (NQO1) inhibitors with potent antiproliferative activities.
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Development of Postoperative Pain in Patients with End-Stage Knee Osteoarthritis Is Associated with Upregulation of Genes Related to Extracellular Matrix Degradation, Inflammation, and Apoptosis Measured in the Peripheral Blood before Knee Surgery.
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Development of Tailor-Made Dendrimer Ternary Complexes for Drug/Gene Co-Delivery in Cancer.
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Dexmedetomidine attenuates isoflurane-induced cognitive impairment through antioxidant, anti-inflammatory and anti-apoptosis in aging rat.
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Dexmedetomidine confers neuroprotection against transient global cerebral ischemia/reperfusion injury in rats by inhibiting inflammation through inactivation of the TLR-4/NF-?B pathway.
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Dextromethorphan Suppresses Lipopolysaccharide-Induced Epigenetic Histone Regulation in the Tumor Necrosis Factor-? Expression in Primary Rat Microglia.
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Diacerein Downregulates NLRP3/Caspase-1/IL-1? and IL-6/STAT3 Pathways of Inflammation and Apoptosis in a Rat Model of Cadmium Testicular Toxicity.
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Diatom-derived polyunsaturated aldehydes activate cell death in human cancer cell lines but not normal cells.
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Diet-induced obesity exacerbates auditory degeneration via hypoxia, inflammation, and apoptosis signaling pathways in CD/1 mice.
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Dietary fat without body weight gain increases in vivo MCF-7 human breast cancer cell growth and decreases natural killer cell cytotoxicity.
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Dietary isothiocyanate iberin inhibits growth and induces apoptosis in human glioblastoma cells.
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Dietary Mixed Cereal Grains Ameliorate the Azoxymethane and Dextran Sodium Sulfate-Induced Colonic Carcinogenesis in C57BL/6J Mice.
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Dietary olive oil and corn oil differentially affect experimental breast cancer through distinct modulation of the p21ras signaling and the proliferation-apoptosis balance.
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Dietary Polyphenols, Resveratrol and Pterostilbene Exhibit Antitumor Activity on an HPV E6-Positive Cervical Cancer Model: An in vitro and in vivo Analysis.
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Dietary protocatechuic acid abrogates male reproductive dysfunction in streptozotocin-induced diabetic rats via suppression of oxidative damage, inflammation and caspase-3 activity.
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Dietary Supplementation of L-Arginine and N-Carbamylglutamate Attenuated the Hepatic Inflammatory Response and Apoptosis in Suckling Lambs with Intrauterine Growth Retardation.
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Dietary turmeric post-treatment decreases DMBA-induced hamster buccal pouch tumor growth by altering cell proliferation and apoptosis-related markers.
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Difference in the Inhibitory Effect of Temozolomide on TJ905 Glioma Cells and Stem Cells.
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Differences in Expression of Uroplakin III, Cytokeratin 7, and Cyclooxygenase-2 in Canine Proliferative Urothelial Lesions of the Urinary Bladder.
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Different apoptotic regulation of TRAIL-caspase pathway in HBV- and HCV-related hepatocellular carcinoma.
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Different expression of apoptotic proteins between HBV-infected and non-HBV-infected hepatocellular carcinoma.
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Differential activity of caspase-3 regulates susceptibility of lung and breast tumor cell lines to Paclitaxel.
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Differential apoptotic and redox regulatory activities of curcumin and its derivatives.
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Differential caspase-3 expression in noncancerous, premalignant and cancer tissues of stomach and its clinical implication.
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Differential effects of eugenol against hepatic inflammation and overall damage induced by ischemia/re-perfusion injury.
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DIFFERENTIAL EFFICACY OF SSTR1, 2 AND 5 AGONISTS IN THE INHIBITION OF C6 GLIOMA GROWTH IN NUDE MICE.
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Differential expression of apoptosis-related proteins in various cellular components of ameloblastomas.
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Differential expression of intracellular apoptotic signaling molecules in tumor and tumor-infiltrating lymphocytes during development of invasion and/or metastasis of gastric carcinoma.
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Differential expression of mycobacterial antigen MPT64, apoptosis and inflammatory markers in multinucleated giant cells and epithelioid cells in granulomas caused by Mycobacterium tuberculosis.
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Differential inhibitory effects of conjugated linoleic acid isomers on mouse forestomach neoplasia induced by benzo(a)pyrene.
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Differential MicroRNA-34a Expression and Tumor Suppressor Function in Retinoblastoma Cells.
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Differential protection with inhibitors of caspase-8 and caspase-3 in murine models of tumor necrosis factor and Fas receptor-mediated hepatocellular apoptosis.
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Differential protein expression between esophageal squamous cell carcinoma and dysplasia, and prognostic significance of protein markers.
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Differential targets and subcellular localization of antitumor alkyl-lysophospholipid in leukemic versus solid tumor cells.
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Diffuse malignant mesothelioma of the peritoneum and pleura, analysis of markers.
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Diffusion MRI biomarkers predict the outcome of irreversible electroporation in a pancreatic tumor mouse model.
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Diindolylmethane and Lupeol Modulates Apoptosis and Cell Proliferation in N-Butyl-N-(4-Hydroxybutyl) Nitrosamine Initiated and Dimethylarsinic Acid Promoted rat Bladder Carcinogenesis.
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Dinaciclib prolongs survival in the LSL-KrasG12D/+ ; LSL-Trp53R172H/+ ; Pdx-1-Cre (KPC) transgenic murine models of pancreatic ductal adenocarcinoma.
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Dioscin attenuates hepatic ischemia-reperfusion injury in rats through inhibition of oxidative-nitrative stress, inflammation and apoptosis.
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Dioscin suppresses hepatocellular carcinoma tumor growth by inducing apoptosis and regulation of TP53, BAX, BCL2 and cleaved CASP3.
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Diphenyl difluoroketone: a curcumin derivative with potent in vivo anticancer activity.
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Direct current electrical fields induce apoptosis in oral mucosa cancer cells by NADPH oxidase-derived reactive oxygen species.
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Discovery and pharmacologic characterization of CP-724,714, a selective ErbB2 tyrosine kinase inhibitor.
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Discovery of a new binding site on human choline kinase ?1: design, synthesis, crystallographic studies, and biological evaluation of asymmetrical bispyridinium derivatives.
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Discovery of a novel class of dimeric Smac mimetics as potent IAP antagonists resulting in a clinical candidate for the treatment of cancer (AZD5582).
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Disruption of oncogenic liver-intestine cadherin (CDH17) drives apoptotic pancreatic cancer death.
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Distinct interferon-gamma and interleukin-9 expression in cutaneous and oral lichen planus.
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Distinct pro-apoptotic properties of Zhejiang saffron against human lung cancer via a caspase-8-9-3 cascade.
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Distinctive roles of PHAP proteins and prothymosin-alpha in a death regulatory pathway.
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Diterpenoid C of Radix Curcumae: An inhibitor of proliferation and inducer of apoptosis in human colon adenocarcinoma cells acting via inhibiting MAPK signaling pathway.
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Diterpenylhydroquinones from natural ent-labdanes induce apoptosis through decreased mitochondrial membrane potential.
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DLC1 suppresses distant dissemination of human hepatocellular carcinoma cells in nude mice through reduction of RhoA GTPase activity, actin cytoskeletal disruption and down-regulation of genes involved in metastasis.
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DM-1, sodium 4-[5-(4-hydroxy-3-methoxyphenyl)-3-oxo-penta-1,4-dienyl]-2-methoxy-phenolate: a curcumin analog with a synergic effect in combination with paclitaxel in breast cancer treatment.
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DNA Damage Response Proteins and Oxygen Modulate Prostaglandin E2 Growth Factor Release in Response to Low and High LET Ionizing Radiation.
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DNA targeting polyaza macrobicyclic dizinc(II) complexes promoting high in vitro caspase dependent anti-proliferative activity against human carcinoma cancer cells.
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DNA-ligase IV and DNA-protein kinase play a critical role in deficient caspases activation in apoptosis-resistant cancer cells by using doxorubicin.
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Does nicotine impact tramadol abuse? Insights from neurochemical and neurobehavioral changes in mice.
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Does structural commonality of metal complex formation by PAC-1 (anticancer), DHBNH (anti-HIV), AHL (autoinducer), and UCS1025A (anticancer) denote mechanistic similarity? Signal transduction and medical aspects.
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Donkey milk inhibits triple-negative breast tumor progression and is associated with increased cleaved-caspase-3 expression.
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Donor Preconditioning After the Onset of Brain Death With Dopamine Derivate n-Octanoyl Dopamine Improves Early Posttransplant Graft Function in the Rat.
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Dose-dependent protective effect of baicalin against testicular torsion-detorsion in rats.
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Doubling down on the PI3K-AKT-mTOR pathway enhances the antitumor efficacy of PARP inhibitor in triple negative breast cancer model beyond BRCA-ness.
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Down-regulated expression of OPCML predicts an unfavorable prognosis and promotes disease progression in human gastric cancer.
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Down-regulation of c-FLIP Enhances death of cancer cells by smac mimetic compound.
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Down-regulation of caspase 3 in breast cancer: a possible mechanism for chemoresistance.
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Down-Regulation of the Mammalian Target of Rapamycin (mTOR) Pathway Mediates the Effects of the Paeonol-Platinum(II) Complex in Human Thyroid Carcinoma Cells and Mouse SW1736 Tumor Xenografts.
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Down-Regulation of ZEB1 by miR-199a-3p Overexpression Restrains Tumor Stem-Like Properties and Mitochondrial Function of Non-Small Cell Lung Cancer.
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Downregulating lncRNA PRNCR1 ameliorates LPS-induced pulmonary vascular endothelial cell injury by modulating miR-330-5p/TLR4 axis.
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Downregulation of cyclooxygenase-1 is involved in gastric mucosal apoptosis via death signaling in portal hypertensive rats.
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Downregulation of microRNA-214 improves therapeutic potential of allogeneic bone marrow-derived mesenchymal stem cell by targeting PIM-1 in rats with acute liver failure.
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Downregulation of PLK1 by RNAi attenuates the tumorigenicity of esophageal squamous cell carcinoma cells via promoting apoptosis and inhibiting angiogenesis.
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Downregulation of thymidylate synthase and E2F1 by arsenic trioxide in mesothelioma.
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Doxorubicin hydrochloric increases tumour coagulation and end-point survival in percutaneous microwave ablation of tumours in a VX2 rabbit tumour model.
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Doxorubicin induces apoptosis in normal and tumor cells via distinctly different mechanisms. intermediacy of H(2)O(2)- and p53-dependent pathways.
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Doxorubicin, L-arginine, or their combination as a prophylactic agent against hepatic carcinoma in mice.
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Doxorubicin-loaded iron oxide nanoparticles for glioblastoma therapy: a combinational approach for enhanced delivery of nanoparticles.
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Doxorubicin/heparin composite nanoparticles for caspase-activated prodrug chemotherapy.
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Drug conjugation to hyaluronan widens therapeutic indications for ovarian cancer.
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Drug-delivering-drug platform-mediated potent protein therapeutics via a non-endo-lysosomal route.
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Drug-induced caspase-3 activation in a Ewing tumor cell line and primary Ewing tumor cells.
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DT390-triTMTP1, a novel fusion protein of diphtheria toxin with tandem repeat TMTP1 peptide, preferentially targets metastatic tumors.
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Dual mTORC1/2 Inhibition Sensitizes Testicular Cancer Models to Cisplatin Treatment.
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Dual Targeting of ERBB2/ERBB3 for the Treatment of SLC3A2-NRG1-Mediated Lung Cancer.
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Dual Targeting of Phosphoinositide 3-Kinase and Mammalian Target of Rapamycin Using NVP-BEZ235 as a Novel Therapeutic Approach in Human Ovarian Carcinoma.
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Dual-channel surface plasmon resonance monitoring of intracellular levels of the p53-MDM2 complex and caspase-3 induced by MDM2 antagonist Nutlin-3.
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Duchesnea phenolic fraction inhibits in vitro and in vivo growth of cervical cancer through induction of apoptosis and cell cycle arrest.
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Duration of brain death and cold ischemia time, but not warm ischemia time, increases expression of genes associated with apoptosis in transplanted kidneys from deceased donors.
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Dysregulation of BDNF/TrkB signaling mediated by NMDAR/Ca2+/calpain might contribute to postoperative cognitive dysfunction in aging mice.
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E mu-bcl-2 transgene facilitates spontaneous transformation of early pre-B and immunoglobulin-secreting cells but not T cells.
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E1A oncogene expression inhibits PTHrP P3 promoter activity and sensitizes human prostate cancer cells to TNF-induced apoptosis.
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E1A sensitizes cancer cells to TRAIL-induced apoptosis through enhancement of caspase activation.
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Early combined treatment with cilostazol and bone marrow-derived endothelial progenitor cells markedly attenuates pulmonary arterial hypertension in rats.
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Early prediction of tumor response to treatment: pre-clinical validation of 99mTc-duramycin.
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Echinacoside Induces Apoptosis in Human SW480 Colorectal Cancer Cells by Induction of Oxidative DNA Damages.
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Ecto-5'-Nucleotidase Overexpression Reduces Tumor Growth in a Xenograph Medulloblastoma Model.
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Ectopically expressed perforin-1 is proapoptotic in tumor cell lines by increasing caspase-3 activity and the nuclear translocation of cytochrome C.
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Effect of ?, ? momorcharin on viability, caspase activity, cytochrome c release and on cytosolic calcium levels in different cancer cell lines.
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Effect of adenovirus-mediated RNA interference of IL-1? expression on spinal cord injury in rats.
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Effect of Anacardium occidentale leaf extract on human acute lymphoblastic leukaemia cell lines.
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Effect of bevacizumab on expression level of GLI1 and ING4 in colon cancer animal model.
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Effect of Chemotherapeutic Drugs on Caspase-3 Activity, as a Key Biomarker for Apoptosis in Ovarian Tumor Cell Cultured as Monolayer. A Pilot Study.
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Effect of Chitosan Magnetic Nanoparticles Loaded with Ang2-siRNA Plasmids on the Growth of Melanoma Xenografts in Nude Mice.
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Effect of combined therapy of mesenchymal stem cells with GLP-1 receptor agonist, exenatide, on early-onset nephropathy induced in diabetic rats.
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Effect of dapagliflozin and/or L-arginine on solid tumor model in mice: The interaction between nitric oxide, transforming growth factor-beta 1, autophagy, and apoptosis.
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Effect of dietary glutamine on tumor glutathione levels and apoptosis-related proteins in DMBA-induced breast cancer of rats.
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Effect of Enterococcus faecalis 2001 on colitis and depressive-like behavior in dextran sulfate sodium-treated mice: involvement of the brain-gut axis.
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Effect of homeopathic treatment on gene expression in Copenhagen rat tumor tissues.
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Effect of imidazoline-1 receptor agonists on renal dysfunction in rats associated with chronic, sequential fructose and ethanol administration.
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EFFECT OF INTRAPERITONEAL RESUSCITATION WITH DIFFERENT CONCENTRATIONS OF SODIUM PYRUVATE ON INTESTINAL ISCHEMIA REPERFUSION INJURY IN HEMORRHAGIC SHOCK RAT.
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Effect of Maxing Shigan Tang on H1N1 Influenza A Virus-Associated Acute Lung Injury in Mice.
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Effect of miR-132-3p on sepsis-induced acute kidney injury in mice via regulating HAVCR1/KIM-1.
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Effect of Phosphorylated-Extracellular Regulated Kinase 1/2 Inhibitor on Retina from Light-induced Photoreceptor Degeneration.
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Effect of pregabalin administration upon reperfusion in a rat model of hyperglycemic stroke: Mechanistic insights associated with high-mobility group box 1.
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Effect of rapamycin (RAPA) on the growth of lung cancer and its mechanism in mice with A549.
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Effect of Sorbus domestica and its active constituents in an experimental model of colitis rats induced by acetic acid.
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Effect of strawberry (Fragaria × ananassa) leaves extract on diabetic nephropathy in rats.
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Effect of sulglycotide on the apoptotic processes associated with indomethacin-induced gastric mucosal injury.
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Effect of targeted magnetic nanoparticles containing 5-FU on expression of bcl-2, bax and caspase 3 in nude mice with transplanted human liver cancer.
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Effect of targeting mitogen-activated protein kinase on cardiac remodeling in rats.
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Effect of the GLP-1 analog exendin-4 and oxaliplatin on intrahepatic cholangiocarcinoma cell line and mouse model.
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Effect of the polyamine analogue N1,N11-diethylnorspermine on cell survival and susceptibility to apoptosis of human chondrocytes.
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Effect of the topical administration of N-(2-(4-bromophenylamino)-5-(trifluoromethyl)phenyl)nicotinamide compound in a murine subcutaneous melanoma model.
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Effect of ursolic acid treatment on apoptosis and DNA damage in isoproterenol-induced myocardial infarction.
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Effect of weimaining on apoptosis and Caspase-3 expression in a breast cancer mouse model.
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Effect-enhancing and toxicity-reducing activity of usnic acid in ascitic tumor-bearing mice treated with bleomycin.
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Effective Combined Photodynamic Therapy with Lipid Platinum Chloride Nanoparticles Therapies of Oral Squamous Carcinoma Tumor Inhibition.
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Effective enhancement of X-ray-induced apoptosis in human cancer cells with mutated p53 by siRNA targeting XIAP.
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Effects of 14 single herbs on the induction of caspase-3 in tumor cells: a brief review.
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Effects of a 15% orange-pulp diet on tumorigenesis and immune response in rats with colon tumors.
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Effects of adenovirus vectors mediated human lactoferrin cDNA on mice bearing EMT6 breast carcinoma.
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Effects of alpha-santalol on proapoptotic caspases and p53 expression in UVB irradiated mouse skin.
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Effects of Androgen Receptor Inhibition on Kanamycin-Induced Hearing Loss in Rats.
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Effects of aurothiomalate treatment on canine osteosarcoma in a murine xenograft model.
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Effects of bufalin and cinobufagin on the proliferation of androgen dependent and independent prostate cancer cells.
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Effects of bufalin on the mTOR/p70S6K pathway and apoptosis in esophageal squamous cell carcinoma in nude mice.
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Effects of carboxymethyl chitosan oligosaccharide on regulating immunologic function and inhibiting tumor growth.
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Effects of chidamide and its combination with decitabine on proliferation and apoptosis of leukemia cell lines.
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Effects of chlorella on activities of protein tyrosine phosphatases, matrix metalloproteinases, caspases, cytokine release, B and T cell proliferations, and phorbol ester receptor binding.
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Effects of Cyclin D1 Gene Silencing on cell Proliferation, cell Cycle and Apoptosis of Hepatocellular Carcinoma Cells.
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Effects of Different Chromium Compounds on Hematology and Inflammatory Cytokines in Rats Fed High-Fat Diet.
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Effects of enriched environment on COX-2, leptin and eicosanoids in a mouse model of breast cancer.
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Effects of Ganoderma lucidum Polysaccharides on Different Pathways Involved in the Development of Spinal Cord Ischemia Reperfusion Injury: Biochemical, Histopathologic, and Ultrastructural Analysis in a Rat Model.
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Effects of Hesperidin on H?O?-Treated Chondrocytes and Cartilage in a Rat Osteoarthritis Model.
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Effects of Huaier Extract on Ameliorating Colitis-Associated Colorectal Tumorigenesis in Mice.
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Effects of humanin on experimental colitis induced by 2,4,6-trinitrobenzene sulphonic acid in rats.
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Effects of ischemic preconditioning on myocardium Caspase-3, SOCS-1, SOCS-3, TNF-? and IL-6 mRNA expression levels in myocardium IR rats.
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Effects of isoflurane preconditioning in the delayed phase on myocardial tumor necrosis factor alpha levels and caspase-3 protein expression in a rabbit model of ischemia-reperfusion injury.
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Effects of kinetin riboside on proliferation and proapoptotic activities in human normal and cancer cell lines.
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Effects of MicroRNA-132 Transfection on the Proliferation and Apoptosis of Human Liver Cancer Cells in vitro and in vivo.
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Effects of miR-155 antisense oligonucleotide on breast carcinoma cell line MDA-MB-157 and implanted tumors.
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Effects of Molecular Hydrogen on Methamphetamine-Induced Neurotoxicity and Spatial Memory Impairment.
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Effects of Oxymatrine on the Proliferation and Apoptosis of Human Hepatoma Carcinoma Cells.
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Effects of polyamine depletion by alpha-difluoromethylornithine on in vitro and in vivo biological properties of 4T1 murine mammary cancer cells.
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Effects of propofol on proliferation and apoptosis of cardia cancer cells via MAPK/ERK signaling pathway.
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Effects of Recombinant Circularly Permuted Tumor Necrosis Factor (TNF)-Related Apoptosis-Inducing Ligand (TRAIL) (Recombinant Mutant Human TRAIL) in Combination with 5-Fluorouracil in Human Colorectal Cancer Cell Lines HCT116 and SW480.
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Effects of rosmarinic acid on immunoregulatory activity and hepatocellular carcinoma cell apoptosis in H22 tumor-bearing mice.
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Effects of salvianolic acid a on oxidative stress and liver injury induced by carbon tetrachloride in rats.
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Effects of sequential treatments with chemotherapeutic drugs followed by TRAIL on prostate cancer in vitro and in vivo.
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Effects of short-hairpin RNA-inhibited ?-catenin expression on the growth of human multiple myeloma cells in vitro and in vivo.
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Effects of short-term finasteride on apoptotic factors and androgen receptors in prostate cancer cells.
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Effects of Smac gene over-expression on the radiotherapeutic sensitivities of cervical cancer cell line HeLa.
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Effects of soybean isoflavone on intestinal antioxidant capacity and cytokines in young piglets fed oxidized fish oil.
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Effects of sustained and intermittent paclitaxel therapy on tumor repopulation in ovarian cancer.
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Effects of the novel non-steroidal anti-inflammatory compound [N-(2-thiolethyl)-2- {2- [N'- (2,6- dichlorophenyl) amino] phenyl}acetamide on cytokines and apoptosis in ischaemic rat brain.
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Effects of the proteasome inhibitor PS-341 on apoptosis and angiogenesis in orthotopic human pancreatic tumor xenografts.
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Effects of trans-resveratrol on type 1 diabetes-induced up-regulation of apoptosis and mitogen-activated protein kinase signaling in retinal pigment epithelium of Dark Agouti rats.
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Effects of treatment of rats with indole-3-carbinol on apoptosis in the mammary gland and mammary adenocarcinomas.
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Effects of Zhichan powder on signal transduction and apoptosis-associated gene expression in the substantia nigra of Parkinson's disease rats.
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Efficacy and mechanism of steep pulse irreversible electroporation technology on xenograft model of nude mice: a preclinical study.
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Efficacy of Aerosolized Celecoxib Encapsulated Nanostructured Lipid Carrier in Non-small Cell Lung Cancer in Combination with Docetaxel.
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Efficacy of Carboplatin Alone and in Combination with ABT888 in Intracranial Murine Models of BRCA-Mutated and BRCA-Wild-Type Triple-Negative Breast Cancer.
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Efficacy of intratumoral chemotherapy using arsenic trioxide (As2O3) sustained release tablets for the treatment of neurogliocytoma in nude mice.
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Efficacy of melatonin, IL-25 and siIL-17B in tumorigenesis-associated properties of breast cancer cell lines.
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Efficacy Screening of Gloriosa Superba Extracts in a Murine Pancreatic Cancer Model Using (18)F-FDG PET/CT for Monitoring Treatment Response.
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Efficiency of newly formulated camptothecin with ?-cyclodextrin-EDTA-Fe3O4 nanoparticle-conjugated nanocarriers as an anti-colon cancer (HT29) drug.
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Efficient eradication of hormone-resistant human prostate cancers by inactivated Sendai virus particle.
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Efficient lysis of rhabdomyosarcoma cells by cytokine-induced killer cells: implications for adoptive immunotherapy after allogeneic stem cell transplantation.
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EGCG inhibits growth, invasion, angiogenesis and metastasis of pancreatic cancer.
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EGFR inhibitor C225 increases the radiosensitivity of human lung squamous cancer cells.
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EGR-1 plays a protective role in AMPK inhibitor compound C-induced apoptosis through ROS-induced ERK activation in skin cancer cells.
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EGR2 induces apoptosis in various cancer cell lines by direct transactivation of BNIP3L and BAK.
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eIF4E-phosphorylation-mediated Sox2 upregulation promotes pancreatic tumor cell repopulation after irradiation.
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Electroacupuncture inhibits apoptosis of splenic lymphocytes in traumatized rats through modulation of the TNF-?/NF-?B signaling pathway.
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Electrochemotherapy with Irreversible Electroporation and FOLFIRINOX Improves Survival in Murine Models of Pancreatic Adenocarcinoma.
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Elevated cleaved caspase-3 is associated with shortened overall survival in several cancer types.
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Elevated tumor LDLR expression accelerates LDL cholesterol-mediated breast cancer growth in mouse models of hyperlipidemia.
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Ellagic Acid Induces Novel and Atypical PKC Isoforms and Promotes Caspase-3 Dependent Apoptosis by Blocking Energy Metabolism.
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Ellagic acid, a polyphenolic compound, selectively induces ROS-mediated apoptosis in cancerous B-lymphocytes of CLL patients by directly targeting mitochondria.
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Elucidation of mechanisms underlying the protective effects of olive leaf extract against lead-induced neurotoxicity in Wistar rats.
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Elucidation of molecular targets of mammary cancer chemoprevention in the rat by organoselenium compounds using cDNA microarray.
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EMAP-II-dependent lymphocyte killing is associated with hypoxia in colorectal cancer.
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Embelin Suppresses Growth of Human Pancreatic Cancer Xenografts, and Pancreatic Cancer Cells Isolated from KrasG12D Mice by Inhibiting Akt and Sonic Hedgehog Pathways.
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Emerging Role of Lymphocyte Antigen-6 Family of Genes in Cancer and Immune Cells.
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Encapsulation of a new quinoxaline derivative in PLGA alters the pattern of its anticancer potency and induces apoptosis.
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Endostatin sensitizes p53-deficient non-small-cell lung cancer to genotoxic chemotherapy by targeting DNA-dependent protein kinase catalytic subunit.
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Endothelial cell surface ATP synthase-triggered caspase-apoptotic pathway is essential for k1-5-induced antiangiogenesis.
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Endothelin-1 receptor antagonists prevent the development of pulmonary emphysema in rats.
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Endowing Indole-Based Tubulin Inhibitors with an Anchor for Derivatization: Highly Potent 3-Substituted Indolephenstatins and Indoleisocombretastatins.
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Enhanced antitumor and anti-angiogenic effects of metronomic Vinorelbine combined with Endostar on Lewis lung carcinoma.
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Enhanced antitumor efficacy of a DR5-specific TRAIL variant over recombinant human TRAIL in a bioluminescent ovarian cancer xenograft model.
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Enhanced apoptotic effects by downregulating Mcl-1: Evidence for the improvement of photodynamic therapy with Celecoxib.
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Enhanced Bax upregulating in mitochondria for deep tumor therapy based on SO2 prodrug loaded Au-Ag hollow nanotriangles.
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Enhanced cytotoxicity and activation of ROS-dependent c-Jun NH2-Terminal Kinase and Caspase-3 by low doses of Tetrandrine loaded nanoparticles in Lovo cells ---a possible Trojan strategy against cancer.
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Enhanced docetaxel-mediated cytotoxicity in human prostate cancer cells through knockdown of cofilin-1 by carbon nanohorn delivered siRNA.
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Enhanced effect of gemcitabine by emodin against pancreatic cancer in vivo via cytochrome C-regulated apoptosis.
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Enhanced GSTP1 expression in transitional cell carcinoma of urinary bladder is associated with altered apoptotic pathways.
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Enhanced Immunotherapy Based on Photodynamic Therapy for Both Primary and Lung Metastasis Tumor Eradication.
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Enhanced in vivo targeting of estrogen receptor alpha signaling in murine mammary adenocarcinoma by nilotinib/rosuvastatin novel combination.
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Enhanced protection against pulmonary hypertension with sildenafil and endothelial progenitor cell in rats.
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Enhanced radiosensitivity of non-small-cell lung cancer (NSCLC) by adenovirus-mediated ING4 gene therapy.
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Enhanced suppression of proliferation and migration in highly-metastatic lung cancer cells by combination of valproic acid and coumarin-3-carboxylic acid and its molecular mechanisms of action.
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Enhanced therapeutic effect of an antiangiogenesis peptide on lung cancer in vivo combined with salmonella VNP20009 carrying a Sox2 shRNA construct.
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Enhanced tumor suppression by adenoviral PTEN gene therapy combined with cisplatin chemotherapy in small-cell lung cancer.
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Enhancement of paclitaxel-mediated cytotoxicity in lung cancer cells by 17-allylamino geldanamycin: in vitro and in vivo analysis.
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Enhancing responsiveness of pancreatic cancer cells to gemcitabine treatment under hypoxia by heme oxygenase-1 inhibition.
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Enhancing the Anticancer Activity of Antrodia cinnamomea in Hepatocellular Carcinoma Cells via Cocultivation With Ginger: The Impact on Cancer Cell Survival Pathways.
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Enhancing the in vitro and in vivo activity of itraconazole against breast cancer using miltefosine-modified lipid nanocapsules.
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Enoxaparin attenuates doxorubicin induced cardiotoxicity in rats via interfering with oxidative stress, inflammation and apoptosis.
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Ent-Dihydrotucumanoic acid promotes apoptosis in PC-3 human prostate cancer cells.
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Enterocyte proliferation and apoptosis in the caudal small intestine is influenced by the composition of colonizing commensal bacteria in the neonatal gnotobiotic pig.
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Epidermal growth factor receptor mutation status in cell-free DNA supernatant of bronchial washings and brushings.
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Epigallocatechin-3-gallate pretreatment attenuates doxorubicin-induced cardiotoxicity in rats: A mechanistic study.
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Epigallocatechin-3-Gallate: The Prospective Targeting of Cancer Stem Cells and Preventing Metastasis of Chemically-Induced Mammary Cancer in Rats.
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Epigenetic inactivation of BCL6B, a novel functional tumour suppressor for gastric cancer, is associated with poor survival of gastric cancer.
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Epigenetic modulation of endogenous tumor suppressor expression in lung cancer xenografts suppresses tumorigenicity.
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Epigenetics-Based Tumor Cells Pyroptosis for Enhancing the Immunological Effect of Chemotherapeutic Nanocarriers.
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Epithelial derived-matrix metalloproteinase (MMP9) exhibits a novel defensive role of tumor suppressor in colitis associated cancer by activating MMP9-Notch1-ARF-p53 axis.
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Epithelial ovarian cancer: feasibility of image-guided intratumoral radiofrequency hyperthermia-enhanced direct gene therapy.
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ErbB2 Targeted Epigenetic Modulation: Anti-tumor Efficacy of the ADC Trastuzumab-HDACi ST8176AA1.
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Erianin inhibits human cervical cancer cell through regulation of tumor protein p53 via the extracellular signal-regulated kinase signaling pathway.
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Erythrocyte-Derived Theranostic Nanoplatforms for Near Infrared Fluorescence Imaging and Photodestruction of Tumors.
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Erythropoietin Pretreatment Attenuates Seawater Aspiration-Induced Acute Lung Injury in Rats.
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Erythropoietin suppresses the activation of pro-apoptotic genes in head and neck squamous cell carcinoma xenografts exposed to surgical trauma.
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Esculentoside A suppresses breast cancer stem cell growth through stemness attenuation and apoptosis induction by blocking IL-6/STAT3 signaling pathway.
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Essential Oil from the Resin of Protium heptaphyllum: Chemical Composition, Cytotoxicity, Antimicrobial Activity, and Antimutagenicity.
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Estrogen and soy isoflavonoids decrease sensitivity of medulloblastoma and central nervous system primitive neuroectodermal tumor cells to chemotherapeutic cytotoxicity.
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Estrogen receptor ? (ESR1) over-expression mediated apoptosis in Hep3B cells by binding with SP1 proteins.
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Estrogen receptor beta enhances chemotherapy response of GBM cells by down regulating DNA damage response pathways.
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Estrone-salicylaldehyde N-methylated thiosemicarbazone hybrids and their copper complexes: solution structure, stability and anticancer activity in tumour spheroids.
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Ethanolic extracts of Pluchea indica (L.) leaf pretreatment attenuates cytokine-induced ?-cell apoptosis in multiple low-dose streptozotocin-induced diabetic mice.
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Etoposide-Induced Apoptosis in Cancer Cells Can Be Reinforced by an Uncoupled Link between Hsp70 and Caspase-3.
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Eucalyptus kino: a treasure trove of polyphenols eradicating tumors in-vivo by elevating caspase-3 level, inhibiting TGF-? and NF-?b gene expression.
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Eugenol promotes functional recovery and alleviates inflammation, oxidative stress, and neural apoptosis in a rat model of spinal cord injury.
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Eupafolin Suppresses Esophagus Cancer Growth by Targeting T-LAK Cell-Originated Protein Kinase.
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Evaluation of Anti-Inflammatory and Antiapoptotic Effects of Bone Marrow and Adipose-Derived Mesenchymal Stem Cells in Acute Alkaline Corneal Burn.
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Evaluation of anti-tumorigenic activity of BP3B against colon cancer with patient-derived tumor xenograft model.
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Evaluation of apoptogenic adenovirus type 5 oncolytic vectors in a Syrian hamster head and neck cancer model.
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Evaluation of Apoptosis Induction by Newcastle Disease Virus LaSota Strain in Human Breast Carcinoma Cells.
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Evaluation of apoptosis-associated protein (Bcl-2, Bax, cleaved caspase-3 and p53) expression in canine mammary tumors: An immunohistochemical and prognostic study.
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Evaluation of Bcl-2, Bcl-x and cleaved caspase-3 in malignant peripheral nerve sheath tumors and neurofibromas.
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Evaluation of Carcinogenic Potential of Diuron in a Rat Mammary Two-Stage Carcinogenesis Model.
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Evaluation of gemfibrozil effects on a marine fish (Sparus aurata) combining gene expression with conventional endocrine and biochemical endpoints.
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Evaluation of genotoxic and apoptotic potential of Hypericum adenotrichum Spach. in vitro.
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Evaluation of in vitro anticancer activity of Ocimum basilicum, Alhagi maurorum, Calendula officinalis and their parasite Cuscuta campestris.
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Evaluation of Iodine-125 Interstitial Brachytherapy Using Micro-Positron Emission Tomography/Computed Tomography with 18F-Fluorodeoxyglucose in Hepatocellular Carcinoma HepG2 Xenografts.
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Evaluation of Loading Strategies to Improve Tumor Uptake of Gemcitabine in a Murine Orthotopic Bladder Cancer Model Using Ultrasound and Microbubbles.
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Evaluation of miRNAs Related with Nuclear Factor Kappa B Pathway in Lipopolysaccharide Induced Acute Respiratory Distress Syndrome.
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Evaluation of MMP2 and Caspase-3 expression in 107 cases of papillary thyroid carcinoma and its association with prognostic factors.
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Evaluation of naproxen and cromolyn activities against cancer cells viability, proliferation, apoptosis, p53 and gene expression of survivin and caspase-3.
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Evaluation of p53, Caspase-3, Bcl-2, and Ki-67 markers in oral squamous cell carcinoma and premalignant epithelium in a sample from Alava Province (Spain).
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Evaluation of redox and bioenergetics states in the liver of vitamin A-treated rats.
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Evaluation of targeted arterial delivery of the branched chain fatty acid 12-methyltetradecanoic acid as a novel therapy for solid tumors.
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Evaluation of the Cytotoxic and Apoptogenic Effects of Glabridin and Its Effect on Cytotoxicity and Apoptosis Induced by Doxorubicin Toward Cancerous Cells.
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Evaluation of the neuroprotective effect of chrysin via modulation of endogenous biomarkers in a rat model of spinal cord injury.
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Evaluation of the Potential Diagnostic Utility of the Determination of Selected Caspases-Markers Involved in the Regulation of Apoptosis-In Patients with Ovarian Cancer.
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Evaluation of therapeutic effects of natural killer (NK) cell-based immunotherapy in mice using in vivo apoptosis bioimaging with a caspase-3 sensor.
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Evaluation of [(18)F]CP18 as a Substrate-Based Apoptosis Imaging Agent for the Assessment of Early Treatment Response in Oncology.
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Everolimus (RAD001) and anti-angiogenic cyclophosphamide show long-term control of gastric cancer growth in vivo.
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Evidence for the mode of action of the highly cytotoxic Streptomyces polyketide kendomycin.
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Evidence of securin-mediated resistance to gefitinib-induced apoptosis in human cancer cells.
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Evidence that transgenes encoding components of the Wnt signaling pathway preferentially induce mammary cancers from progenitor cells.
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Evodiamine activates cellular apoptosis through suppressing PI3K/AKT and activating MAPK in glioma.
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EWS Knockdown and Taxifolin Treatment Induced Differentiation and Removed DNA Methylation from p53 Promoter to Promote Expression of Puma and Noxa for Apoptosis in Ewing's Sarcoma.
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Ex-vivo perfusion as a successful strategy for reduction of ischemia-reperfusion injury in prolonged muscle flap preservation - A gene expression study.
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Examining the effector mechanisms of Xuebijing injection on COVID-19 based on network pharmacology.
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Exercise training enhances tumor necrosis factor-alpha-induced expressions of anti-apoptotic genes without alterations in caspase-3 activity in rat epididymal adipocytes.
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Exfoliated graphene nanosheets: pH-sensitive drug carrier and anti-cancer activity.
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Exogenous fatty acid binding protein 4 promotes human prostate cancer cell progression.
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Exosomes Derived From Adipose-Derived Mesenchymal Stem Cells Ameliorate Radiation-Induced Brain Injury by Activating the SIRT1 Pathway.
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Exosomes derived from circRNA Rtn4-modified BMSCs attenuate TNF-?-induced cytotoxicity and apoptosis in murine MC3T3-E1 cells by sponging miR-146a.
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Experimental photodynamic therapy for liver cancer cell-implanted nude mice by an indole-3-acetic acid and intense pulsed light combination.
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Exploring new applications of tulip tree (Liriodendron tulipifera L.): leaf essential oil as apoptotic agent for human glioblastoma.
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Exploring the protective role of apocynin, a specific NADPH oxidase inhibitor, in cisplatin-induced cardiotoxicity in rats.
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Exposure of pregnant sows to deoxynivalenol during 35-70 days of gestation does not affect pathomorphological and immunohistochemical properties of fetal organs.
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Expression and mechanisms of long non-coding RNA genes MEG3 and ANRIL in gallbladder cancer.
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Expression and prognostic significance of osteopontin and caspase-3 in hepatocellular carcinoma patients after curative resection.
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Expression levels of apoptosis-related proteins predict clinical outcome in anaplastic large cell lymphoma.
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Expression levels of cleaved caspase-3 and caspase-3 in tumorigenesis and prognosis of oral tongue squamous cell carcinoma.
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Expression of apoptosis related proteins during malignant progression in chronic ulcerative colitis.
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Expression of Bax and apoptosis-related proteins in human esophageal squamous cell carcinoma including dysplasia.
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Expression of caspase-3 and -7 does not correlate with the extent of apoptosis in primary breast carcinomas.
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Expression of caspase-3 and hypoxia inducible factor 1? in hepatocellular carcinoma complicated by hemorrhage and necrosis.
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Expression of caspases 3, 6 and 8 is increased in parallel with apoptosis and histological aggressiveness of the breast lesion.
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Expression of caspases-3, -6 and -8 and their relation to apoptosis in non-small cell lung carcinoma.
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Expression of cIAP-1 correlates with nodal metastasis in squamous cell carcinoma of the tongue.
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Expression of cysteine protease protein 32 in prostatic adenocarcinoma correlates with tumor grade.
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Expression of endothelial and inducible nitric oxide synthase and caspase-3 in tonsillar cancer, chronic tonsillitis and healthy tonsils.
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Expression of Fas ligand and caspase-3 contributes to formation of immune escape in gastric cancer.
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Expression of Inflammatory and Cell Death Program Genes and Comet DNA Damage Assay Induced by Escherichia coli in Layer Hens.
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Expression of long intergenic non-coding RNA, regulator of reprogramming, and its prognostic value in patients with glioblastoma.
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Expression of Matrix Metalloproteinase-2, but not Caspase-3, Facilitates Distinction between Benign and Malignant Thyroid Follicular Neoplasms.
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Expression of multiple apoptosis-regulatory genes in human breast cancer cell lines and primary tumors.
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Expression of neurodegenerative disease-related proteins and caspase-3 in glioneuronal tumours.
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Expression of pro-inflammatory cytokine and caspase genes promotes neuronal apoptosis in pontine reticular formation after spinal cord transection.
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Expression of programmed cell death 5 protein inhibits progression of lung carcinoma in vitro and in vivo via the mitochondrial apoptotic pathway.
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Expression of PTEN and Caspase-3 and their clinicopathological significance in primary gastric malignant lymphoma.
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Expression of PTEN and FHIT is involved in regulating the balance between apoptosis and proliferation in lung carcinomas.
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Expression of survivin, cyclinD1, p21(WAF1), caspase-3 in cervical cancer and its relation with prognosis.
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Expression of survivin, p53, and caspase 3 in Barrett's esophagus carcinogenesis.
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Expression of the active caspase-3 in children and adolescents with classical Hodgkin lymphoma.
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Expression of the antiapoptotic gene seladin-1 and octreotide-induced apoptosis in growth hormone-secreting and nonfunctioning pituitary adenomas.
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Expression of the hematopoietic stem cell antigen Sca-1 (LY-6A/E) in liver sinusoidal endothelial cells: possible function of Sca-1 in endothelial cells.
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Expression of the pro-apoptotic caspase 3/CPP32 in cutaneous basal and squamous cell carcinomas.
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Expression of TLR-2 in hepatocellular carcinoma is associated with tumour proliferation, angiogenesis and Caspase-3 expression.
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Expression of tumor necrosis factor alpha converting enzyme in endocrine cancers.
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Expression of tumour necrosis factor-related apoptosis-inducing ligand and caspase-3 in relation to grade of inflammation and stage of fibrosis in chronic hepatitis C.
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Expression patterns of miR-221 and its target Caspase-3 in different cancer cell lines.
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Expressional changes after histone deacetylase inhibition by valproic acid in LNCaP human prostate cancer cells.
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Extra copies of chromosomes 16 and X in invasive breast carcinomas are related to aggressive phenotype and poor prognosis.
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Extracellular 2'5'-oligoadenylate synthetase 2 mediates T-cell receptor CD3-? chain down-regulation via caspase-3 activation in oral cancer.
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Extracellular matrix metalloproteinase inducer (CD147) confers resistance of breast cancer cells to Anoikis through inhibition of Bim.
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Extract Derived from Cedrus atlantica Acts as an Antitumor Agent on Hepatocellular Carcinoma Growth In Vitro and In Vivo.
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Extraction, Characterization, Antitumor and Immunological Activities of Hemicellulose Polysaccharide from Astragalus radix Herb Residue.
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Extracts of Qizhu decoction inhibit hepatitis and hepatocellular carcinoma in vitro and in C57BL/6 mice by suppressing NF-?B signaling.
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Facile Synthesis of Zn-Doped Bi2O3 Nanoparticles and Their Selective Cytotoxicity toward Cancer Cells.
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Facio-Genital Dysplasia-5 Regulates Matrix Adhesion and Survival of Human Endothelial Cells.
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Failure of activation of caspase-9 induces a higher threshold for apoptosis and cisplatin resistance in testicular cancer.
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FAK activates AKT-mTOR signaling to promote the growth and progression of MMTV-Wnt1-driven basal-like mammary tumors.
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FAM60A promotes cisplatin resistance in lung cancer cells by activating SKP2 expression.
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Fas (CD95)- and tumor necrosis factor-mediated apoptosis in liver endothelial cells: role of caspase-3 and the p38 MAPK.
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Fas, FasL, and cleaved caspases 8 and 3 in glioblastomas: A tissue microarray-based study.
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Fas-induced pulmonary apoptosis and inflammation during indirect acute lung injury.
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Fas-mediated pathway and apoptosis in normal, hyperplastic, and neoplastic endometrium.
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Fast Activation and Tracing of Caspase-3 Involved Cell Apoptosis by Combined Electrostimulation and Smart Signal-Amplified SERS Nanoprobes.
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Feasibility outcomes of a presurgical randomized controlled trial exploring the impact of caloric restriction and increased physical activity versus a wait-list control on tumor characteristics and circulating biomarkers in men electing prostatectomy for prostate cancer.
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Features of the Copy Number Variation of Certain Genes in Tumor Cells in Patients with Serous Ovarian Adenocarcinoma.
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Ferulic acid enhances the radiation sensitivity of lung and liver carcinoma cells by collapsing redox homeostasis: mechanistic involvement of Akt/p38 MAPK signalling pathway.
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FGF9/FGFR1 promotes cell proliferation, epithelial-mesenchymal transition, M2 macrophage infiltration and liver metastasis of lung cancer.
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Fish oil administration mediates apoptosis of Walker 256 tumor cells by modulation of p53, Bcl-2, caspase-7 and caspase-3 protein expression.
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FLAG-tagged CD19-specific CAR-T cells eliminate CD19-bearing solid tumor cells in vitro and in vivo.
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Flavokawain C exhibits anti-tumor effects on in vivo HCT 116 xenograft and identification of its apoptosis-linked serum biomarkers via proteomic analysis.
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Flavonoid components in Scutellaria baicalensis inhibit nicotine-induced proliferation, metastasis and lung cancer-associated inflammation in vitro.
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Flower extract of Allium atroviolaceum triggered apoptosis, activated caspase-3 and down-regulated antiapoptotic Bcl-2 gene in HeLa cancer cell line.
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Fluorescence lifetime imaging microscopy of chemotherapy-induced apoptosis resistance in a syngenic mouse tumor model.
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Fluoride and diethylnitrosamine coexposure enhances oxido-inflammatory responses and caspase-3 activation in liver and kidney of adult rats.
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Fluorogenic Substrates for In Situ Monitoring of Caspase-3 Activity in Live Cells.
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Fluvastatin reduces proliferation and increases apoptosis in women with high grade breast cancer.
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FR901228, a novel histone deacetylase inhibitor, induces cell cycle arrest and subsequent apoptosis in refractory human pancreatic cancer cells.
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Free Radical Production, Inflammation and Apoptosis in Patients Treated With Titanium Mandibular Fixations-An Observational Study.
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FTY720 induces necrotic cell death and autophagy in ovarian cancer cells: A protective role of autophagy.
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FTY720, a fungus metabolite, inhibits in vivo growth of androgen-independent prostate cancer.
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Fumonisin B1-induced apoptosis is associated with delayed inhibition of protein kinase C, nuclear factor-kappaB and tumor necrosis factor alpha in LLC-PK1 cells.
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Functional genomic characterization of delipidation elicited by trans-10, cis-12-conjugated linoleic acid (t10c12-CLA) in a polygenic obese line of mice.
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Functional protection of pentoxifylline against spinal cord ischemia/reperfusion injury in rabbits: necrosis and apoptosis effects.
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Functions of the AP-2? gene in activating apoptosis and inhibiting proliferation of gastric cancer cells both
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Fungus-mediated synthesis of silver nanoparticles and evaluation of antitumor activity.
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Fuzheng Qingjie Granules Inhibit Growth of Hepatoma Cells via Inducing Mitochondria-Mediated Apoptosis and Enhancing Immune Function.
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G6PD downregulation triggered growth inhibition and induced apoptosis by regulating STAT3 signaling pathway in esophageal squamous cell carcinoma.
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GABA tea prevents cardiac fibrosis by attenuating TNF-alpha and Fas/FasL-mediated apoptosis in streptozotocin-induced diabetic rats.
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Galangin Inhibits Gastric Cancer Growth Through Enhancing STAT3 Mediated ROS Production.
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Galangin suppresses human laryngeal carcinoma via modulation of caspase-3 and AKT signaling pathways.
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Galectin-1 exhibits a protective effect against hepatotoxicity induced by dextran sulfate sodium in mice.
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Gallic acid from Terminalia chebula inhibited the growth of esophageal carcinoma cells by suppressing the Hippo signal pathway.
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Gallic Acid Hindered Lung Cancer Progression by Inducing Cell Cycle Arrest and Apoptosis in A549 Lung Cancer Cells via PI3K/Akt Pathway.
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Gallic Acid Impedes Non-Small Cell Lung Cancer Progression via Suppression of EGFR-Dependent CARM1-PELP1 Complex.
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Gallic acid induces apoptosis via caspase-3 and mitochondrion-dependent pathways in vitro and suppresses lung xenograft tumor growth in vivo.
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Gallic acid potentiates the apoptotic effect of paclitaxel and carboplatin via overexpression of Bax and P53 on the MCF-7 human breast cancer cell line.
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Gamma-aminobutyric acid induces tumor cells apoptosis via GABABR1·?-arrestins·JNKs signaling module.
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Gamma-Glutamyl Cysteine Attenuates Tissue Damage and Enhances Tissue Regeneration in a rat Model of Lead-Induced Nephrotoxicity.
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Gamma-tocopherol enhances apoptotic effects of lovastatin in human colorectal carcinoma cell line (HT29).
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Ganglion cells apoptosis in diabetic rats as early prediction of glaucoma: a study of Brn3b gene expression and association with change of quantity of NO, caspase-3, NF-?B, and TNF-?.
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Ganoderma atrum polysaccharide induces anti-tumor activity via the mitochondrial apoptotic pathway related to activation of host immune response.
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Ganoderma atrum polysaccharide induces antitumor activity via the mitochondrial apoptotic pathway related to activation of host immune response.
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Ganodermanontriol inhibits expression of special AT rich sequence binding protein 1 gene in human hepatocellular carcinoma.
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Gap junction enhancer increases efficacy of cisplatin to attenuate mammary tumor growth.
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Garcinol Inhibits Cell Proliferation and Promotes Apoptosis in Pancreatic Adenocarcinoma Cells.
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Gastroprotective effects of oleuropein and thymol on indomethacin-induced gastric ulcer in Sprague-Dawley rats.
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Gefitinib inhibits malignant melanoma cells through the VEGF/AKT signaling pathway.
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Gemcitabine Mechanism of Action Confounds Early Assessment of Treatment Response by 3'-Deoxy-3'-[18F]Fluorothymidine in Preclinical Models of Lung Cancer.
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Gemcitabine-based therapy for pancreatic cancer using the squalenoyl nucleoside monophosphate nanoassemblies.
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Gene expression analysis for predicting gemcitabine sensitivity in pancreatic cancer patients.
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Gene expression profiling analysis contributes to understanding the association between non-syndromic cleft lip and palate, and cancer.
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Gene transfer of constitutively active caspase-3 induces apoptosis in a human hepatoma cell line.
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Generation of reactive oxygen species by polyenylpyrroles derivatives causes DNA damage leading to G2/M arrest and apoptosis in human oral squamous cell carcinoma cells.
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Genetic variant in CASP3 affects promoter activity and risk of esophageal squamous cell carcinoma.
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Genotoxic, cytostatic, antineoplastic and apoptotic effects of newly synthesized antitumour steroidal esters.
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Geraniol isolated from lemon grass to mitigate doxorubicin-induced cardiotoxicity through Nrf2 and NF-?B signaling.
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Germacrone Inhibits Cell Proliferation and Induces Apoptosis in Human Esophageal Squamous Cell Carcinoma Cells.
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Ginger (
Zingiber
officinale
) prevents severe damage to the lungs due to hyperoxia and
inflammation
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Ginger (Zingiber officinale Roscoe) for the treatment and prevention of necrotizing enterocolitis.
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Gingko Biloba protects cardiomyocytes against acute doxorubicin induced cardiotoxicity by suppressing oxidative stress.
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Ginkgetin aglycone attenuates the apoptosis and inflammation response through nuclear factor-kB signaling pathway in ischemic-reperfusion injury.
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Ginkgo biloba extract (EGb 761) induces apoptosis by the activation of caspase-3 in oral cavity cancer cells.
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Ginkgo biloba Extract Reduces Hippocampus Inflammatory Responses, Improves Cardiac Functions And Depressive Behaviors In A Heart Failure Mouse Model.
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Ginsenoside Rb2 Ameliorates LPS-Induced Inflammation and ER Stress in HUVECs and THP-1 Cells via the AMPK-Mediated Pathway.
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Ginsenoside Rh1 Induces MCF-7 Cell Apoptosis and Autophagic Cell Death through ROS-Mediated Akt Signaling.
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Glial-specific retrovirally mediated gas1 gene expression induces glioma cell apoptosis and inhibits tumor growth in vivo.
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Glioma-induced inhibition of caspase-3 in microglia promotes a tumor-supportive phenotype.
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Glioma-targeted therapy using Cilengitide nanoparticles combined with UTMD enhanced delivery.
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Glucocorticoids potently block tumour necrosis factor-alpha- and lipopolysaccharide-induced apoptotic cell death in bovine glomerular endothelial cells upstream of caspase 3 activation.
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Glutathiolation regulates tumor necrosis factor-alpha-induced caspase-3 cleavage and apoptosis: key role for glutaredoxin in the death pathway.
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Glutathione S-Transferase pi-1 Knockdown Reduces Pancreatic Ductal Adenocarcinoma Growth by Activating Oxidative Stress Response Pathways.
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Glycerol enhances CDDP-induced growth inhibition of thyroid anaplastic carcinoma tumor carrying mutated p53 gene.
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Glycosylation of anthocyanins enhances the apoptosis of colon cancer cells by handicapping energy metabolism.
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GOLPH3 inhibition reverses oxaliplatin resistance of colon cancer cells via suppression of PI3K/AKT/mTOR pathway.
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Gonadotropin-mediated chemoresistance: Delineation of molecular pathways and targets.
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Gramine inhibits angiogenesis and induces apoptosis via modulation of TGF-? signalling in 7,12 dimethylbenz[a]anthracene (DMBA) induced hamster buccal pouch carcinoma.
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Granzyme B leakage-induced apoptosis is a crucial mechanism of cell death in nasal-type NK/T-cell lymphoma.
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Grape proanthocyanidins induce apoptosis by loss of mitochondrial membrane potential of human non-small cell lung cancer cells in vitro and in vivo.
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Grape seed proanthocyanidins induce apoptosis and inhibit metastasis of highly metastatic breast carcinoma cells.
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Grape seeds and skin induce tumor growth inhibition via G1-phase arrest and apoptosis in mice inoculated with Ehrlich ascites carcinoma.
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Graphene-modified CePO4 nanorods effectively treat breast cancer-induced bone metastases and regulate macrophage polarization to improve osteo-inductive ability.
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Green tea polyphenol targets the mitochondria in tumor cells inducing caspase 3-dependent apoptosis.
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Grifola frondosa polysaccharides induce breast cancer cell apoptosis via the mitochondrial-dependent apoptotic pathway.
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Ground-glass opacity-featured lung adenocarcinoma has no response to chemotherapy.
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Growth Hormone Protects the Intestine Preserving Radiotherapy Efficacy on Tumors: A Short-Term Study.
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Growth inhibition and apoptotic effect of alpha-eleostearic acid on human breast cancer cells.
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Growth inhibition of colon cancer cells by transfection of dominant-negative apoptosis signal-regulating kinase-1.
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Growth inhibitory and antimetastatic effect of green tea polyphenols on metastasis-specific mouse mammary carcinoma 4T1 cells in vitro and in vivo systems.
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Growth suppression of human lung cancer cells and implanted tumors by adenovirus-mediated transfer of the PTEN gene.
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Growth, invasion, metastasis, differentiation, angiogenesis and apoptosis of gastric cancer regulated by expression of PTEN encoding products.
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GSK2801, a BAZ2/BRD9 Bromodomain Inhibitor, Synergizes with BET Inhibitors to Induce Apoptosis in Triple-Negative Breast Cancer.
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Gypenosides induced G0/G1 arrest via inhibition of cyclin E and induction of apoptosis via activation of caspases-3 and -9 in human lung cancer A-549 cells.
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Hax-1: a regulator of calcium signaling and apoptosis progression with multiple roles in human disease.
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Hazelnut and neuroprotection: Improved memory and hindered anxiety in response to intra-hippocampal A? injection.
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HBXIP, a binding protein of HBx, regulates maintenance of the G2/M phase checkpoint induced by DNA damage and enhances sensitivity to doxorubicin-induced cytotoxicity.
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HDAC11 deletion reduces fructose-induced cardiac dyslipidemia, apoptosis and inflammation by attenuating oxidative stress injury.
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Heart and iron deficiency anaemia in rats with renal insufficiency: the role of hepcidin.
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Heat shock protein 70-2 (HSP70-2) a novel cancer testis antigen that promotes growth of ovarian cancer.
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Heat-induced apoptosis via caspase-3 activation in tumour cells carrying mutant p53.
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Heat-induced p53-dependent signal transduction and its role in hyperthermic cancer therapy.
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Helicobacter pylori infection combined with DENA revealed altered expression of p53 and 14-3-3 isoforms in Gulo(-/-) mice.
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Hematopoietic stem cells and endothelial cell precursors express Tie-2, CD31 and CD45.
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Heparin-functionalized Pluronic nanoparticles to enhance the antitumor efficacy of sorafenib in gastric cancers.
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Hepatic arterial infusion but not systemic application of cetuximab in combination with oxaliplatin significantly reduces growth of CC531 colorectal rat liver metastases.
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Hepatoprotective effect of arjunolic acid against cisplatin-induced hepatotoxicity: Targeting oxidative stress, inflammation, and apoptosis.
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Hepatoprotective effects of IL-22 on fulminant hepatic failure induced by d-galactosamine and lipopolysaccharide in mice.
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Hepatoprotective Effects of Soybean Embryo by Enhancing Adiponectin-Mediated AMP-Activated Protein Kinase ? Pathway in High-Fat and High-Cholesterol Diet-Induced Nonalcoholic Fatty Liver Disease.
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Hepatoprotective effects of syringin on fulminant hepatic failure induced by D-galactosamine and lipopolysaccharide in mice.
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Hepatorenal protective effects of protocatechuic acid in rats administered with anticancer drug methotrexate.
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Herbal extract "Songyou Yin" inhibits tumor growth and prolongs survival in nude mice bearing human hepatocellular carcinoma xenograft with high metastatic potential.
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Herbal formula of Bushen Jianpi combined with sorafenib inhibits hepatocellular carcinoma growth by promoting cell apoptosis and blocking the cell cycle.
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Heterogeneous susceptibility to spontaneous and induced apoptosis characterizes two related transplantable melanomas with different biological properties.
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HGS-ETR1, a fully human TRAIL-receptor 1 monoclonal antibody, induces cell death in multiple tumour types in vitro and in vivo.
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High dosing of ?-tocopherol inhibits rat liver regeneration by modifying signal transducer and activator of transcription protein expression and its correlation with cell redox state and retinoid metabolism.
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High Fat Diet Increases and the Polyphenol, S17834, Decreases Acetylation of the SirT1-Dependent Lysine-382 on p53 and Apoptotic Signaling in Atherosclerotic Lesion-Prone Aortic Endothelium of Normal Mice.
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High iodine effects on the proliferation, apoptosis, and migration of papillary thyroid carcinoma cells as a result of autophagy induced by BRAF kinase.
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High levels of expression and nuclear localization of interleukin-1 beta converting enzyme (ICE) and CPP32 in favorable human neuroblastomas.
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High-intensity focused ultrasound enhances the effect of bufalin by inducing apoptosis in pancreatic cancer cells.
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High-Refined-Carbohydrate and High-Fat Diets Induce Comparable Hepatic Tumorigenesis in Male Mice.
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Higher Anti-Tumor Efficacy of the Dual HER3-EGFR Antibody MEHD7945a Combined with Ionizing Irradiation in Cervical Cancer Cells.
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Highly bioavailable curcumin powder suppresses articular cartilage damage in rats with mono-iodoacetate (MIA)-induced osteoarthritis.
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Highly potent monomethyl auristatin E prodrug activated by caspase-3 for the chemoradiotherapy of triple-negative breast cancer.
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Hiltonol Cocktail Kills Lung Cancer Cells by Activating Cancer-Suppressors, PKR/OAS, and Restraining the Tumor Microenvironment.
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Hinokitiol, a natural tropolone derivative, offers neuroprotection from thromboembolic stroke in vivo.
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Hippophae rhamnoides polysaccharides protect IPEC-J2 cells from LPS-induced inflammation, apoptosis and barrier dysfunction in vitro via inhibiting TLR4/NF-?B signaling pathway.
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Hispolon Induces Apoptosis through JNK1/2-mediated Activation of a Caspase-8, -9, and -3-dependent Pathway in Acute Myeloid Leukemia (AML) Cells and Inhibits AML Xenograft Tumor Growth in Vivo.
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Hispolon Induces Apoptosis, Suppresses Migration and Invasion of Glioblastoma Cells and Inhibits GBM Xenograft Tumor Growth In Vivo.
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Histologic evaluation of Ki-67 and cleaved caspase-3 expression in feline mammary carcinoma.
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Hitting two oncogenic machineries in cancer cells: cooperative effects of the multi-kinase inhibitor ponatinib and the BET bromodomain blockers JQ1 or dBET1 on human carcinoma cells.
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Host-Defense Peptides Caerin 1.1 and 1.9 Stimulate TNF-Alpha-Dependent Apoptotic Signals in Human Cervical Cancer HeLa Cells.
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HS-104, a PI3K inhibitor, enhances the anticancer efficacy of gemcitabine in pancreatic cancer.
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HSF1 blockade-induced tumor thermotolerance abolishment is mediated by JNK-dependent caspase-3 activation.
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HSP60 mediates the neuroprotective effects of curcumin by suppressing microglial activation.
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HSP70 inhibitor combined with cisplatin suppresses the cervical cancer proliferation in vitro and transplanted tumor growth: An experimental study.
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HuGE systematic review and meta-analysis demonstrate association of CASP-3 and CASP-7 genetic polymorphisms with cancer risk.
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Human amniotic membrane derived-mesenchymal stem cells induce C6 glioma apoptosis in vivo through the Bcl-2/caspase pathways.
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Human bcl-2 Expression, Cleaved Caspase-3, and KSHV LANA-1 in Kaposi Sarcoma Lesions.
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Human biliverdin reductase regulates the molecular mechanism underlying cancer development.
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Human Biofield Therapy Modulates Tumor Microenvironment and Cancer Stemness in Mouse Lung Carcinoma.
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Human breast tissue disposition and bioactivity of limonene in women with early-stage breast cancer.
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Human Chorionic Gonadotropin Suppresses Human Breast Cancer Cell Growth Directly via p53-mediated Mitochondrial Apoptotic Pathway and Indirectly via Ovarian Steroid Secretion.
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Human colorectal cancer cells induce vascular smooth muscle cell apoptosis in an exocrine manner.
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Human lung cancer-derived microparticles enhanced angiogenesis and growth of hepatoma cells in rodent lung parenchyma.
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Human mast cells induce caspase-independent DNA fragmentation in leukemic T cells.
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Human V?2V?2 T cells limit breast cancer growth by modulating cell survival-, apoptosis-related molecules and microenvironment in tumors.
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Huxie Huaji Ointment Induced Apoptosis of Liver Cancer Cells In Vivo and In Vitro by Activating the Mitochondrial Pathway.
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Hybrid Benzoxazole-Coumarin Compounds Induce Death Receptor-Mediated Switchable Apoptotic and Necroptotic Cell Death on HN-5 Head and Neck Cancer Cell Line.
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Hybridized quinoline derivatives as anticancer agents: Design, Synthesis, biological evaluation and molecular docking.
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Hydrogen as additive of HTK solution fortifies myocardial preservation in grafts with prolonged cold ischemia.
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Hydrogen coadministration slows the development of COPD-like lung disease in a cigarette smoke-induced rat model.
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Hydrogen saline offers neuroprotection by reducing oxidative stress in a focal cerebral ischemia-reperfusion rat model.
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Hydrogen Sulfide Ameliorates Lipopolysaccharide-Induced Memory Impairment in Mice by Reducing Apoptosis, Oxidative, and Inflammatory Effects.
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Hydrogen sulfide attenuates myocardial fibrosis in diabetic rats through the JAK/STAT signaling pathway.
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Hydrogen sulfide slows down progression of experimental Alzheimer's disease by targeting multiple pathophysiological mechanisms.
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Hydrogen-Rich Saline Attenuated Subarachnoid Hemorrhage-Induced Early Brain Injury in Rats by Suppressing Inflammatory Response: Possible Involvement of NF-?B Pathway and NLRP3 Inflammasome.
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Hydroxamic Acid Derivatives of ?-Carboline/Hydroxycinnamic Acid Hybrids Inducing Apoptosis and Autophagy through the PI3K/Akt/mTOR Pathways.
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Hydroxysafflor Yellow A mitigated myocardial ischemia/reperfusion injury by inhibiting the activation of the JAK2/STAT1 pathway.
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Hyperbaric oxygen suppressed tumor progression through the improvement of tumor hypoxia and induction of tumor apoptosis in A549-cell-transferred lung cancer.
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Hyperhomocysteinemia inhibits tibial fracture healing in rats through PI3K/AKT signaling pathway.
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Hypericin induced death receptor-mediated apoptosis in photoactivated tumor cells.
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Hyperoside attenuates neuroinflammation, cognitive impairment and oxidative stress via suppressing TNF-?/NF-?B/caspase-3 signaling in type 2 diabetes rats.
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Hyperthermia Suppresses Post - In Vitro Proliferation and Tumor Growth in Murine Malignant Melanoma and Colon Carcinoma.
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Hypothyroidism reduces mammary tumor progression via ?-catenin-activated intrinsic apoptotic pathway in rats.
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Hypoxia-Inducible Factor 1-? (HIF-1?) Induces Apoptosis of Human Uterosacral Ligament Fibroblasts Through the Death Receptor and Mitochondrial Pathways.
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IAP-family protein survivin inhibits caspase activity and apoptosis induced by Fas (CD95), Bax, caspases, and anticancer drugs.
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Ibuprofen abates cypermethrin-induced expression of pro-inflammatory mediators and mitogen-activated protein kinases and averts the nigrostriatal dopaminergic neurodegeneration.
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Identification and biological evaluation of novel benzothiazole derivatives bearing a pyridine-semicarbazone moiety as apoptosis inducers via activation of procaspase-3 to caspase-3.
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Identification and characterization of a novel cytokine, THANK, a TNF homologue that activates apoptosis, nuclear factor-kappaB, and c-Jun NH2-terminal kinase.
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Identification of a cell-wall peptidase (NlpC/P60) from Nocardia seriolae which induce apoptosis in fathead minnow cells.
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Identification of an antitumor effect of demethylzeylasteral on human gastric cancer cells.
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Identification of cytotoxic mediators and their putative role in the signaling pathways during docosahexaenoic acid (DHA)-induced apoptosis of cancer cells.
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Identification of molecular markers for metastasis-related genes in primary breast cancer cells.
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Identification of NEEP21, encoding neuron-enriched endosomal protein of 21 kDa, as a transcriptional target of tumor suppressor p53.
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Identification of novel molecular regulators of tumor necrosis factor-related apoptosis-inducing ligand (TRAIL)-induced apoptosis in breast cancer cells by RNAi screening.
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Identification of polymorphisms in the Caspase-3 gene and their association with lung cancer risk.
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Identification of potential prognostic markers for vulvar cancer using immunohistochemical staining of tissue microarrays.
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Identification of tumor endothelial cells with high aldehyde dehydrogenase activity and a highly angiogenic phenotype.
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Identification of UNC5A as a novel transcriptional target of tumor suppressor p53 and a regulator of apoptosis.
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IEX-1 suppressed apoptotic damage in human intestinal epithelial Caco-2 cells induced by coculturing with macrophage-like THP-1 cells.
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IFN-?-primed human bone marrow mesenchymal stem cells induce tumor cell apoptosis in vitro via tumor necrosis factor-related apoptosis-inducing ligand.
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IFN-?-secreting-mesenchymal stem cells exert an antitumor effect in vivo via the TRAIL pathway.
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Ifosfamide-loaded lipid-core-nanocapsules to increase the anticancer efficacy in MG63 osteosarcoma cells.
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IGF-I receptor activation and BCL-2 overexpression prevent early apoptotic events in human neuroblastoma.
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IGFBP-3 Regulates Esophageal Tumor Growth Through IGF-Dependent and Independent Mechanisms.
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IL-27 enhances the survival of tumor antigen-specific CD8+ T cells and programs them into IL-10-producing, memory precursor-like effector cells.
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IL-29 Exhibits Anti-Tumor Effect on Pan-48 Pancreatic Cancer Cells by Up-regulation of P21 and Bax.
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Imaging biomarkers predict response to anti-HER2 (ErbB2) therapy in preclinical models of breast cancer.
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Imaging Caspase-3 Activation as a Marker of Apoptosis-Targeted Treatment Response in Cancer.
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Imbalance in Protein Thiol Redox Regulation and Cancer-Preventive Efficacy of Selenium.
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Imbalance of the mitochondrial pro- and anti-apoptotic mediators in neuroblastoma tumours with unfavourable biology.
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Immune Responses Raised in an Experimental Colon Carcinoma Model Following Oral Administration of Lactobacillus casei.
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Immune-system-dependent anti-tumor activity of a plant-derived polyphenol rich fraction in a melanoma mouse model.
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Immunization against HIF-1? Inhibits the Growth of Basal Mammary Tumors and Targets Mammary Stem Cells In Vivo.
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Immunocytochemical detection of members of the caspase cascade of apoptosis in childhood medulloblastomas.
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Immunocytochemical detection of members of the caspase cascade of apoptosis in high-grade astrocytomas.
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Immunocytochemical expression of a panel of markers in pleural effusions from patients with primary lung adenocarcinoma.
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Immunoexpression of cleaved caspase-3 shows lower apoptotic area indices in lip carcinomas than in intraoral cancer.
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Immunoexpression of DIABLO, AIF and cytochrome C in gastric adenocarcinoma assessed by tissue Microarray.
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Immunohistochemical analysis of the expression of TNF-alpha, TGF-beta, and caspase-3 in subcutaneous tissue of patients with HIV Lipodystrophy Syndrome.
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Immunohistochemical evaluation of cell proliferation antigen Ki-67 and apoptosis-related proteins Bcl-2 and caspase-3 in oral granular cell tumor.
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Immunohistochemical examination of anti-inflammatory and anti-apoptotic effects of hesperetin on trinitrobenzene sulfonic acid induced colitis in rats.
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Immunohistochemical expression of caspase-1 and -9, uncleaved caspase-3 and -6, cleaved caspase-3 and -6 as well as Bcl-2 in benign epithelium and cancer of the prostate.
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Immunohistochemical expression of caspases 9 and 3 in adenoid cystic carcinoma of salivary glands and association with clinicopathological parameters.
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Immunohistochemical heterogeneity of breast carcinomas negative for estrogen receptors, progesterone receptors and Her2/neu (basal-like breast carcinomas).
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Immunohistochemical investigation of cell cycle and apoptosis regulators (Survivin, beta-Catenin, P53, Caspase 3) in canine appendicular osteosarcoma.
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Immunohistochemical localization of caspase-3 correlates with clinical outcome in B-cell diffuse large-cell lymphoma.
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Immunohistochemical markers associated with brain metastases in patients with nonsmall cell lung carcinoma.
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Immunohistochemical study of NF-?B p65, c-IAP2 and caspase-3 expression in cervical cancer.
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Immunohistochemistry panel segregates molecular types of hepatocellular carcinoma in Brazilian autopsy cases.
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Immunolocalization of the ICE/Ced-3-family protease, CPP32 (Caspase-3), in non-Hodgkin's lymphomas, chronic lymphocytic leukemias, and reactive lymph nodes.
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Immunological protection against HPV16 E7-expressing human esophageal cancer cell challenge by a novel HPV16-E6/E7 fusion protein based-vaccine in a Hu-PBL-SCID mouse model.
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Immunophenotypic profiling of nonsmall cell lung cancer progression using the tissue microarray approach.
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Immunoreactivity to caspase-3, caspase-7, caspase-8, and caspase-9 forms is frequently lost in human prostate tumors.
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Impact of binary waterborne mixtures of nickel and zinc on hypothalamic-pituitary-testicular axis in rats.
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Impact of Bupivacaine on malignant proliferation, apoptosis and autophagy of human colorectal cancer SW480 cells through regulating NF-?B signaling path.
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Impact of L-carnitine and Selenium Treatment on Testicular Apoptosis in Rats Exposed to 2.45 GHz Microwave Energy.
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Impact of short-term Dutasteride treatment on prostate-specific membrane antigen expression in a mouse xenograft model.
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Implications of cleaved caspase 3 and AIF expression in colorectal cancer based on patient age.
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Improved cytotoxic T-lymphocyte immune responses to a tumor antigen by vaccines co-expressing the SLAM-associated adaptor EAT-2.
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In animal models, psychosocial stress-induced (neuro)inflammation, apoptosis and reduced neurogenesis are associated to the onset of depression.
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In silico analysis of the association of hsa-miR-16 expression and cell survival in MDA-MB-231 breast cancer cells subjected to photodynamic therapy.
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In silico and in vitro analysis of coumarin derivative induced anticancer effects by undergoing intrinsic pathway mediated apoptosis in human stomach cancer.
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In silico database screening of potential targets and pathways of compounds contained in plants used for psoriasis vulgaris.
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In situ activation and monitoring of the evolution of the intracellular caspase family.
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In Situ Gel Loaded with Chitosan-Coated Simvastatin Nanoparticles: Promising Delivery for Effective Anti-Proliferative Activity against Tongue Carcinoma.
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In Situ Imaging of Cellular Reactive Oxygen Species and Caspase-3 Activity Using a Multifunctional Theranostic Probe for Cancer Diagnosis and Therapy.
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In utero transplantation of neural stem cells ameliorates maternal inflammation-induced prenatal white matter injury.
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In vitro and in vivo anti-cancer activities of Kuding tea (Ilex kudingcha C.J. Tseng) against oral cancer.
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In vitro and in vivo antitumor activity of bulbus fritillariae cirrhosae and preliminary investigation of its mechanism.
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In vitro and in vivo antitumor effects of acetylshikonin isolated from Arnebia euchroma (Royle) Johnst (Ruanzicao) cell suspension cultures.
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In vitro and in vivo antitumor effects of the Egyptian scorpion Androctonus amoreuxi venom in an Ehrlich ascites tumor model.
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In vitro and in vivo delivery of novel anticancer fusion protein MULT1E/FasTI via adenoviral vectors.
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In vitro and in vivo effects of the carbon monoxide-releasing molecule, CORM-3, in the xenogeneic pig-to-primate context.
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In vitro and in vivo evaluation of the antitumor efficiency of resveratrol against lung cancer.
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In Vitro and In Vivo Evaluation of the Caspase-3 Substrate-Based Radiotracer [(18)F]-CP18 for PET Imaging of Apoptosis in Tumors.
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In vitro and in vivo evaluation of tumor targeting styrene-maleic acid copolymer-pirarubicin micelles: Survival improvement and inhibition of liver metastases.
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In vitro and in vivo induction of apoptosis by capsaicin in pancreatic cancer cells is mediated through ROS generation and mitochondrial death pathway.
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In vitro and in vivo inhibition of neuroblastoma tumor cell growth by AKT inhibitor perifosine.
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In vitro and in vivo inhibitory effects of a Pleurotus eryngii protein on colon cancer cells.
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In vitro anti-tumor effect of high-fluence low-power laser light on apoptosis of human colorectal cancer cells.
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In vitro Anticancer Effects of Stilbene Derivatives: Mechanistic Studies on HeLa and MCF-7 Cells.
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In vitro antitumor mechanism of a novel cyclin-dependent kinase inhibitor CDKI-83.
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In vitro cytotoxic potential of friedelin in human MCF-7 breast cancer cell: Regulate early expression of Cdkn2a and pRb1, neutralize mdm2-p53 amalgamation and functional stabilization of p53.
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In vitro inhibition of fatty acid synthase by 1,2,3,4,6-penta-O-galloyl-?-d-glucose plays a vital role in anti-tumour activity.
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In vitro model of normal, immortalized ovarian surface epithelial and ovarian cancer cells for chemoprevention of ovarian cancer.
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In vitro relationship between serum protein binding to beta-carboline alkaloids: a comparative cytotoxic, spectroscopic and calorimetric assays.
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In vivo activity and pharmacokinetics of nemorosone on pancreatic cancer xenografts.
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In vivo and in vitro assessment of host-parasite interaction between the parasitic copepod Brachiella thynni (Copepoda; Lernaeopodidae) and the farmed Atlantic bluefin tuna (Thunnus thynnus).
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In vivo and in vitro maturation of rabbit oocytes differently affects the gene expression profile, mitochondrial distribution, apoptosis and early embryo development.
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In vivo anti-V-ATPase antibody treatment delays ovarian tumor growth by increasing antitumor immune responses.
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In vivo effects of focused shock waves on tumor tissue visualized by fluorescence staining techniques.
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In vivo evidence of gamma-tocotrienol as a chemosensitizer in the treatment of hormone-refractory prostate cancer.
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In vivo imaging of early stage apoptosis by measuring real-time caspase-3/7 activation.
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In vivo murine breast cancer targeting by magnetic iron nanoparticles involving L. GG cytoplasmic fraction.
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In vivo photoacoustic imaging of chemotherapy-induced apoptosis in squamous cell carcinoma using a near-infrared caspase-9 probe.
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In vivo targeting of SF/HGF and c-met expression via U1snRNA/ribozymes inhibits glioma growth and angiogenesis and promotes apoptosis.
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In Vivo therapeutic potential of mesenchymal stem cell-derived extracellular vesicles with optical imaging reporter in tumor mice model.
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In- and ex-vivo molecular imaging of apoptosis to assess sensitivity of non-small cell lung cancer to EGFR inhibitors using probe-based confocal laser endomicroscopy.
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In-vitro Morphological Assessment of Apoptosis Induced by Nimbolide; A Limonoid from Azadirachta Indica (Neem Tree).
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In-vivo transfection of pcDNA3.1-IGFBP7 inhibits melanoma growth in mice through apoptosis induction and VEGF downexpression.
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Increased apoptosis in high-fat diet-induced nonalcoholic steatohepatitis in rats is associated with c-Jun NH2-terminal kinase activation and elevated proapoptotic Bax.
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Increased baseline RUNX2, caspase 3 and p21 gene expressions in the peripheral blood of disease-modifying anti-rheumatic drug-naïve rheumatoid arthritis patients are associated with improved clinical response to methotrexate therapy.
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Increased expression of Apaf-1 and procaspase-3 and the functionality of intrinsic apoptosis apparatus in non-small cell lung carcinoma.
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Increased HMGB1 and cleaved caspase-3 stimulate the proliferation of tumor cells and are correlated with the poor prognosis in colorectal cancer.
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Increased Hsp27 after androgen ablation facilitates androgen-independent progression in prostate cancer via signal transducers and activators of transcription 3-mediated suppression of apoptosis.
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Increased Numb protein expression predicts poor clinical outcomes in esophageal squamous cell carcinoma patients.
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Increased Occurrence of Caspase-Dependent Apoptosis in Unfavorable Neuroblastomas.
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Increased sensitivity of T lymphocytes to tumor necrosis factor receptor 1 (TNFR1)- and TNFR2-mediated apoptosis in HIV infection: relation to expression of Bcl-2 and active caspase-8 and caspase-3.
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Increased tumor necrosis factor-?, cleaved caspase 3 levels and insulin receptor substrate-1 phosphorylation in the ?(1)-adrenergic receptor knockout mouse.
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Increased type II collagen degradation and very early focal cartilage degeneration is associated with upregulation of chondrocyte differentiation related genes in early human articular cartilage lesions.
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Inducing Apoptosis of Cancer Cells Using Sea Pen Virgularia gustaviana Extract Which is Comparable to Cembrane Diterpene Sarcophine.
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Inducing G2/M Cell Cycle Arrest and Apoptosis through Generation Reactive Oxygen Species (ROS)-Mediated Mitochondria Pathway in HT-29 Cells by Dentatin (DEN) and Dentatin Incorporated in Hydroxypropyl-?-Cyclodextrin (DEN-HP?CD).
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Induction of antiproliferative effect by diosgenin through activation of p53, release of apoptosis-inducing factor (AIF) and modulation of caspase-3 activity in different human cancer cells.
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Induction of apoptosis and down-regulation of Bcl-XL in cancer cells by a novel small molecule, 2[[3-(2,3-dichlorophenoxy)propyl]amino]ethanol.
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Induction of apoptosis and ubiquitin hydrolase gene expression by human serum factors in the early phase of acute myocardial infarction.
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Induction of apoptosis by Centaurea nerimaniae extract in HeLa and MDA-MB-231 cells by a caspase-3 pathway.
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Induction of apoptosis by Cordyceps militaris through activation of caspase-3 in leukemia HL-60 cells.
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Induction of Apoptosis by pierisin-6 in HPV positive HeLa and HepG2 Cancer Cells is mediated by the caspase-3 dependent mitochondrial pathway.
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Induction of apoptosis in cancer cells by NiZn ferrite nanoparticles through mitochondrial cytochrome C release.
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Induction of apoptosis in cancer cells through N-acetyl-l-leucine-modified polyethylenimine-mediated p53 gene delivery.
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Induction of apoptosis in human cancer cells by TZT-1027, an antimicrotubule agent.
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Induction of Apoptosis in Human Hepatocarcinoma SMMC-7721 Cells In Vitro by Psoralen from Psoralea corylifolia.
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Induction of apoptosis in human tumor cells after exposure to Auger electrons: comparison with gamma-ray exposure.
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Induction of colon and cervical cancer cell death by cinnamic acid derivatives is mediated through the inhibition of Histone Deacetylases (HDAC).
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Induction of death receptor ligand-mediated apoptosis in epithelial ovarian carcinoma: The search for sensitizing agents.
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Induction of Mitochondrial Pathways and Endoplasmic Reticulum Stress for Increasing Apoptosis in Ectopic and Orthotopic Neuroblastoma Xenografts.
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Induction of protective and therapeutic anti-cancer immunity by using bispecific anti-idiotype antibody G22-I50 for nasopharyngeal carcinoma.
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Induction of ROS Overload by Alantolactone Prompts Oxidative DNA Damage and Apoptosis in Colorectal Cancer Cells.
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Induction of sirtuin-1 signaling by resveratrol induces human chondrosarcoma cell apoptosis and exhibits antitumor activity.
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Induction of telomere shortening and cellular apoptosis by sodium meta-arsenite in human cancer cell lines.
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Infantile digital fibroma/fibromatosis: a clinicopathologic and immunohistochemical study of 69 tumors from 57 patients with long-term follow-up.
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Infiltrating CTLs in human glioblastoma establish immunological synapses with tumorigenic cells.
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Inflammation induction of dickkopf-1 mediates chondrocyte apoptosis in osteoarthritic joint.
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Inflammation-induced Occludin Downregulation Limits Epithelial Apoptosis by Suppressing Caspase 3 Expression.
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Inflammatory cytokines, apoptotic, tissue injury and remodeling biomarkers in children with congenital heart disease.
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Influence of Canine Macrophage-derived Extracellular Vesicles on Apoptosis in Canine Melanoma and Osteosarcoma Cell Lines.
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Influence of Capsaicin on Inflammatory Cytokines Induced by Lipopolysaccharide in Myoblast Cells Under In vitro Environment.
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Influence of COX-2 inhibition by rofecoxib on serum and tumor progastrin and gastrin levels and expression of PPARgamma and apoptosis-related proteins in gastric cancer patients.
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Influence of gastrin on the expression of cyclooxygenase-2, hepatocyte growth factor and apoptosis-related proteins in gastric epithelial cells.
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Influence of survivin and caspase-3 on cell apoptosis and prognosis in gastric carcinoma.
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Influenza Virus PB1-F2 Protein Induces Cell Death through Mitochondrial ANT3 and VDAC1.
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Inhalation Delivery and Anti-tumor Activity of Celecoxib in Human Orthotopic Non-Small Cell Lung Cancer Xenograft Model.
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Inhaled carbon monoxide prevents acute kidney injury in pigs after cardiopulmonary bypass by inducing a heat shock response.
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Inhibiting a spinal cord signaling pathway protects against ischemia injury in rats.
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Inhibiting aberrant p53-PUMA feedback loop activation attenuates ischaemia reperfusion-induced neuroapoptosis and neuroinflammation in rats by downregulating caspase 3 and the NF-?B cytokine pathway.
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Inhibiting systemic autophagy during interleukin 2 immunotherapy promotes long-term tumor regression.
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Inhibition of 4E-BP1 sensitizes U87 glioblastoma xenograft tumors to irradiation by decreasing hypoxia tolerance.
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Inhibition of apoptosis in human tumour cells by the tumour-associated serpin, SCC antigen-1.
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Inhibition of AURKA Reduces Proliferation and Survival of Gastrointestinal Cancer Cells With Activated KRAS by Preventing Activation of RPS6KB1.
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Inhibition of Aurora-A results in increased cell death in 3-dimensional culture microenvironment, reduced migration and is associated with enhanced radiosensitivity in human nasopharyngeal carcinoma.
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Inhibition of autophagy exerts anti-colon cancer effects via apoptosis induced by p53 activation and ER stress.
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Inhibition of autotaxin with GLPG1690 increases the efficacy of radiotherapy and chemotherapy in a mouse model of breast cancer.
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Inhibition of basal-like breast cancer growth by FTY720 in combination with epidermal growth factor receptor kinase blockade.
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Inhibition of cathepsin S attenuates myocardial ischemia/reperfusion injury by suppressing inflammation and apoptosis.
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Inhibition of cell proliferation by mild hyperthermia at 43?C with Paris Saponin I in the lung adenocarcinoma cell line PC-9.
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Inhibition of DNA methylation attenuates low-dose cadmium-induced cardiac contractile and intracellular Ca(2+) anomalies.
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Inhibition of fibroblast growth factor 19 reduces tumor growth by modulating beta-catenin signaling.
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Inhibition of histone deacetylases by chlamydocin induces apoptosis and proteasome-mediated degradation of survivin.
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Inhibition of HMGB1 protects the retina from ischemia-reperfusion, as well as reduces insulin resistance proteins.
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Inhibition of human breast cancer cell growth and enzymatic activity by a fermented nutraceutical: an in vitro and in vivo study .
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Inhibition of hydrogen sulfide synthesis provides protection for severe acute pancreatitis rats via apoptosis pathway.
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Inhibition of LncRNA Vof-16 expression promotes nerve regeneration and functional recovery after spinal cord injury.
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Inhibition of lung cancer in diethylnitrosamine-induced mice by Rhizoma paridis saponins.
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Inhibition of nuclear factor-kappaB augments antitumor activity of adenovirus-mediated melanoma differentiation-associated gene-7 against lung cancer cells via mitogen-activated protein kinase kinase kinase 1 activation.
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Inhibition of p62/SQSTM1 sensitizes small-cell lung cancer cells to cisplatin-induced cytotoxicity by targeting NEDD9 expression.
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Inhibition of phosphotidylinositol-3 kinase pathway by a novel naphthol derivative of betulinic acid induces cell cycle arrest and apoptosis in cancer cells of different origin.
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Inhibition of poly(ADP-ribose) polymerase (PARP) induces apoptosis in lung cancer cell lines.
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Inhibition of proliferation and migration of luminal and claudin-low breast cancer cells by PDGFR inhibitors.
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Inhibition of proliferation of PC3 cells by the branched-chain fatty acid, 12-methyltetradecanoic acid, is associated with inhibition of 5-lipoxygenase.
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Inhibition of proliferation of prostate cancer cell line, PC-3, in vitro and in vivo using (-)-gossypol.
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Inhibition of Protein Kinase R by C16 Protects the Retinal Ganglion Cells from Hypoxia-induced Oxidative Stress, Inflammation, and Apoptosis.
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Inhibition of RANKL blocks skeletal tumor progression and improves survival in a mouse model of breast cancer bone metastasis.
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Inhibition of Signal Transducer and Activator of Transcription 3 and Cyclooxygenase-2 Is Involved in Radiosensitization of Cepharanthine in HeLa Cells.
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Inhibition of Stat3 activation suppresses caspase-3 and the ubiquitin-proteasome system, leading to preservation of muscle mass in cancer cachexia.
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Inhibition of the JAK/STAT pathway with ruxolitinib overcomes cisplatin resistance in non-small-cell lung cancer NSCLC.
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Inhibition of the p38 MAPK pathway attenuates renal injury in pregnant rats with acute necrotizing pancreatitis.
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Inhibition of tumor growth by recombinant adenovirus containing human lactoferrin through inducing tumor cell apoptosis in mice bearing EMT6 breast cancer.
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Inhibition of tumor progression by oral piceatannol in mouse 4T1 mammary cancer is associated with decreased angiogenesis and macrophage infiltration.
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Inhibitory activity of acteoside in melanoma via regulation of the ER?-Ras/Raf1-STAT3 pathway.
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Inhibitory Effect of a ?-Tocopherol-Rich Mixture of Tocopherols on the Formation and Growth of LNCaP Prostate Tumors in Immunodeficient Mice.
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Inhibitory Effect of Lentivirus-Mediated Gag-Caspase-8 on the Growth of HER-2-Overexpressing Primary Human Breast Cancer Cells.
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Inhibitory Effect of Orally Administered 5-Aminolevulinic Acid on Prostate Carcinogenesis in the FVB-Transgenic Adenocarcinoma of a Mouse Prostate (FVB-TRAMP) Model.
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Inhibitory effect of polyphenol cyanidin on TNF-alpha-induced apoptosis through multiple signaling pathways in endothelial cells.
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Inhibitory effect of voluntary running wheel exercise on the growth of human pancreatic Panc-1 and prostate PC-3 xenograft tumors in immunodeficient mice.
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Inhibitory Effects of Different Forms of Tocopherols, Tocopherol Phosphates, and Tocopherol Quinones on Growth of Colon Cancer Cells.
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Inhibitory Effects of Nobiletin on Hepatocellular Carcinoma In Vitro and In Vivo.
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Inhibitory effects of phenolic alkaloids of menispermum dauricum on gastric cancer in vivo.
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Inhibitory effects of resveratrol and pterostilbene on human colon cancer cells: a side-by-side comparison.
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Inhibitory effects of the ultrasound-targeted microbubble destruction-mediated herpes simplex virus-thymidine kinase/ganciclovir system on ovarian cancer in mice.
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Inhibitory mechanisms of Agaricus blazei Murill on the growth of prostate cancer in vitro and in vivo.
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Inhibitory role of peroxisome proliferator-activated receptor gamma in hepatocarcinogenesis in mice and in vitro.
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Inotodiol inhibits cells migration and invasion and induces apoptosis via p53-dependent pathway in HeLa cells.
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Insulin-like growth factor binding protein-related protein 1 (IGFBP-rP1) has potential tumour-suppressive activity in human lung cancer.
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Insulin-like growth factor-1 binding protein 3 (IGFBP-3) promotes recovery from trauma-induced expression of inflammatory and apoptotic factors in retina.
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Insulin-Mediated Inhibition of p38 Mitogen-Activated Protein Kinase Protects Cardiomyocytes in Severe Burns.
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Intake of grape-derived polyphenols reduces C26 tumor growth by inhibiting angiogenesis and inducing apoptosis.
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Integrating virtual screening and biochemical experimental approach to identify potential anti-cancer agents from drug databank.
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Integration of Ca2+ signaling regulates the breast tumor cell response to simvastatin and doxorubicin.
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Integrative findings indicate anti-tumor biotargets and molecular mechanisms of calycosin against osteosarcoma.
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Integrin ?v?6-specific therapy for pancreatic cancer developed from foot-and-mouth-disease virus.
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Integrin-linked kinase regulates cell proliferation and tumour growth in murine colitis-associated carcinogenesis.
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Integrin?1 modulates tumour resistance to gemcitabine and serves as an independent prognostic factor in pancreatic adenocarcinomas.
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Interaction between tumour-infiltrating B cells and T cells controls the progression of hepatocellular carcinoma.
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Interferon-gamma targets cancer cells and osteoclasts to prevent tumor-associated bone loss and bone metastases.
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Interleukin-10 plasmid DNA inhibits subcutaneous tumor growth of Colon26 adenocarcinoma in mice.
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Interleukin-13 interferes with activation-induced t-cell apoptosis by repressing p53 expression.
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Interleukin-17 receptor-like gene is a novel antiapoptotic gene highly expressed in androgen-independent prostate cancer.
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Interleukin-27 Gene Delivery Targeting IL-6R?-Expressing Cells as a Stress Response Therapy.
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Interleukin-32 enhances cytotoxic effect of natural killer cells to cancer cells via activation of death receptor 3.
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Intermittent and continuous imatinib in a human GIST xenograft model carrying KIT exon 17 resistance mutation D816H.
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Interstitial chemotherapy using thermosensitive gel-coated ricin in nude mice bearing a human hepatoma.
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Intestinal neoplasia induced by low dietary folate is associated with altered tumor expression profiles and decreased apoptosis in mouse normal intestine.
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Intestinal probiotics E. coli Nissle 1917 as a targeted vehicle for delivery of p53 and Tum-5 to solid tumors for cancer therapy.
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Intra-arterially infused carbon dioxide-saturated solution for sensitizing the anticancer effect of cisplatin in a rabbit VX2 liver tumor model.
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Intrabodies targeting human papillomavirus 16 E6 and E7 oncoproteins for therapy of established HPV-associated tumors.
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Intracerebral administration of ultrasound-induced dissolution of lipid-coated GDNF microbubbles provides neuroprotection in a rat model of Parkinson's disease.
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Intramammary lipopolysaccharide infusion alters gene expression but does not induce lysis of the bovine corpus luteum.
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Intranasal Piperine-Loaded Chitosan Nanoparticles as Brain-Targeted Therapy in Alzheimer's Disease: Optimization, Biological Efficacy, and Potential Toxicity.
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Intranasal Tadalafil nanoemulsions: formulation, characterization and pharmacodynamic evaluation.
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Intratumoral talimogene laherparepvec injection with concurrent preoperative radiation in patients with locally advanced soft-tissue sarcoma of the trunk and extremities: phase IB/II trial.
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Intravenous administration of human amniotic mesenchymal stem cells improves outcomes in rats with acute traumatic spinal cord injury.
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Intravital molecular imaging reveals the restrained capacity of CTLs in the killing of tumor cells in the liver.
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Inverse correlation of apoptotic and angiogenic markers in squamous cell carcinoma of the head and neck.
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Investigating isoquinoline derivatives for inhibition of inhibitor of apoptosis proteins for ovarian cancer treatment.
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Investigating the Multitarget Pharmacological Mechanism of Ursolic Acid Acting on Colon Cancer: A Network Pharmacology Approach.
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Investigation of intravenous delivery of nanoliposomal topotecan for activity against orthotopic glioblastoma xenografts.
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Investigation of platinum nanoparticle properties against U87 glioblastoma multiforme.
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Investigation of the Inhibitory Effect of Platycodin D in Human Transitional Cell Carcinoma Cell Line 5637.
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Investigation of the protective role of chrysin within the framework of oxidative and inflammatory markers in experimental testicular ischaemia/reperfusion injury in rats.
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Involvement of CASP3 promoter polymorphism (-1337 C?>?G) in the development and progression of non-small cell lung cancer.
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Involvement of caspase-3, lipid peroxidation and TNF-alpha in causing apoptosis of macrophages by coordinately expressed Salmonella phenotype under stress conditions.
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Involvement of Fas (CD95/APO-1) and Fas ligand in apoptosis induced by ganciclovir treatment of tumor cells transduced with herpes simplex virus thymidine kinase.
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Involvement of Nrf2/HO-1 antioxidant signaling and NF-?B inflammatory response in the potential protective effects of vincamine against methotrexate-induced nephrotoxicity in rats: cross talk between nephrotoxicity and neurotoxicity.
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In vivo and in vitro inhibition of human gastric cancer progress by upregulating Kank1 gene.
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In vivo anticancer effects of Momordica charantia seed fat on hepatocellular carcinoma in a rat model.
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In vivo treatment of HCV core-positive HepG2 cells with the transfer of recombinant caspase-3 using a 2'-5' OAS promoter.
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Ionically-crosslinked milk protein nanoparticles as flutamide carriers for effective anticancer activity in prostate cancer-bearing rats.
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Ionizing radiation enhances the therapeutic potential of TRAIL in prostate cancer in vitro and in vivo: Intracellular mechanisms.
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Irbesartan mitigates acute liver injury, oxidative stress, and apoptosis induced by acetaminophen in mice.
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Irisin Contributes to the Hepatoprotection of Dexmedetomidine during Intestinal Ischemia/Reperfusion.
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Irradiation-dependent effects on tumor perfusion and endogenous and exogenous hypoxia markers in an A549 xenograft model.
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Irregularly shaped inclusion cysts display increased expression of Ki67, Fas, Fas ligand, and procaspase-3 but relatively little active caspase-3.
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Isolation and characterization of a novel gene, hRFI, preferentially expressed in esophageal cancer.
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Isolation and Functional Characterization of Single Domain Antibody Modulators of Caspase-3 and Apoptosis.
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Isolation of 4,4'-bond secalonic acid D from the marine-derived fungus Penicillium oxalicum with inhibitory property against hepatocellular carcinoma.
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Isolation of fatty acids with anticancer activity from Protaetia brevitarsis larva.
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Isolation, Formulation, and Efficacy Enhancement of Morin Emulsified Carriers Against Lung Toxicity in Rats.
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Isolinderalactone regulates the BCL-2/caspase-3/PARP pathway and suppresses tumor growth in a human glioblastoma multiforme xenograft mouse model.
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Isosteviol Sodium Protects Against Permanent Cerebral Ischemia Injury in Mice via Inhibition of NF-?B-Mediated Inflammatory and Apoptotic Responses.
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Istaroxime Inhibits Motility and Down-Regulates Orai1 Expression, SOCE and FAK Phosphorylation in Prostate Cancer Cells.
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Jinzhi protects lipopolysaccharide-treated mice against mortality by repairing intestinal mucosal barrier damage and intestinal microecology.
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JTC801 Induces pH-dependent Death Specifically in Cancer Cells and Slows Growth of Tumors in Mice.
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Jurkat cells respond to biotin deficiency with increased nuclear translocation of NF-kappaB, mediating cell survival.
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Kadsura heteroclita stem ethanol extract protects against carbon tetrachloride-induced liver injury in mice via suppression of oxidative stress, inflammation, and apoptosis.
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Kaempferol and quercetin, components of Ginkgo biloba extract (EGb 761), induce caspase-3-dependent apoptosis in oral cavity cancer cells.
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Ketogenic diet combined with antioxidant N-acetylcysteine inhibits tumor growth in a mouse model of anaplastic thyroid cancer.
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Ki-67 is a Prognostic Biomarker of Survival after Radiofrequency Ablation of Liver Malignancies.
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Kinetin riboside preferentially induces apoptosis by modulating Bcl-2 family proteins and caspase-3 in cancer cells.
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Knockdown of ghrelin-O-acyltransferase attenuates colitis through the modulation of inflammatory factors and tight junction proteins in the intestinal epithelium.
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Knockdown of Livin inhibits growth and invasion of gastric cancer cells through blockade of the MAPK pathway in vitro and in vivo.
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Knockdown of long noncoding RNA XIST mitigates the apoptosis and inflammatory injury of microglia cells after spinal cord injury through miR-27a/Smurf1 axis.
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Knockdown of NF-E2-related factor 2 inhibits the proliferation and growth of U251MG human glioma cells in a mouse xenograft model.
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Kukoamine A inhibits human glioblastoma cell growth and migration through apoptosis induction and epithelial-mesenchymal transition attenuation.
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Kushen flavonoids induce apoptosis in tumor cells by inhibition of NF-kappaB activation and multiple receptor tyrosine kinase activities.
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l-theanine alleviates liver and kidney dysfunction in septic rats induced by cecal ligation and puncture.
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l-Theanine improves functional recovery after traumatic spinal cord injury in rats.
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Label-Free and Homogenous Detection of Caspase-3-Like Proteases by Disrupting Homodimerization-Directed Bipartite Tetracysteine Display.
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Label-Free Infrared Spectral Histology of Skin Tissue Part II: Impact of a Lumican-Derived Peptide on Melanoma Growth.
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Lactacystin, a proteasome inhibitor, potentiates the apoptotic effect of parthenolide, an inhibitor of NFkappaB activation, on drug-resistant mouse leukemia L1210 cells.
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Lamin B, caspase-3 activity, and apoptosis induction by a combination of HMG-CoA reductase inhibitor and COX-2 inhibitors: a novel approach in developing effective chemopreventive regimens.
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Lamin B2 promotes the progression of triple negative breast cancer via mediating cell proliferation and apoptosis.
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Large-scale preparation of active caspase-3 in E. coli by designing its thrombin-activatable precursors.
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LC3B upregulation by NANOG promotes immune resistance and stem-like property through hyperactivation of EGFR signaling in immune-refractory tumor cells.
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LCL161 increases paclitaxel-induced apoptosis by degrading cIAP1 and cIAP2 in NSCLC.
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Lentiviral delivery of novel fusion protein IL12/FasTI for cancer immune/gene therapy.
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Lentivirus-mediated RNA interference targeting E2F-1 inhibits human gastric cancer MGC-803 cell growth in vivo.
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Leptin and camel milk abate oxidative stress status, genotoxicity induced in valproic acid rat model of autism.
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Leptin as a novel profibrogenic cytokine in hepatic stellate cells: mitogenesis and inhibition of apoptosis mediated by extracellular regulated kinase (Erk) and Akt phosphorylation.
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Let-7a microRNA suppresses therapeutics-induced cancer cell death by targeting caspase-3.
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Levels of Hepatic Activating Transcription Factor 6 and Caspase-3 Are Downregulated in Mice after Excessive Training.
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Levosimendan suppresses oxidative injury, apoptotic signaling and mitochondrial degeneration in streptozotocin-induced diabetic cardiomyopathy.
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LFC131 peptide-conjugated polymeric nanoparticles for the effective delivery of docetaxel in CXCR4 overexpressed lung cancer cells.
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LFM-A13, a potent inhibitor of polo-like kinase, inhibits breast carcinogenesis by suppressing proliferation activity and inducing apoptosis in breast tumors of mice.
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Licochalcone A attenuates abdominal aortic aneurysm induced by angiotensin II via regulating the miR-181b/SIRT1/HO-1 signaling.
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Licochalcone E present in licorice suppresses lung metastasis in the 4T1 mammary orthotopic cancer model.
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Licorice Ameliorates Cisplatin-Induced Hepatotoxicity Through Antiapoptosis, Antioxidative Stress, Anti-Inflammation, and Acceleration of Metabolism.
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Light-emitting diode irradiation induces AKT/mTOR-mediated apoptosis in human pancreatic cancer cells and xenograft mouse model.
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Limaprost reduces motor disturbances by increasing the production of insulin-like growth factor I in rats subjected to spinal cord injury.
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LINC00612/miR-31-5p/Notch1 Axis Regulates Apoptosis, Inflammation, and Oxidative Stress in Human Pulmonary Microvascular Endothelial Cells Induced by Cigarette Smoke Extract.
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Lipophilic Grape Seed Proanthocyanidin Exert Anti-Proliferative and Pro-apoptotic Effects on PC3 Human Prostate Cancer Cells and Suppresses PC3 Xenograft Tumor Growth in Vivo.
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Lipopolysaccharides promote pulmonary fibrosis in silicosis through the aggravation of apoptosis and inflammation in alveolar macrophages.
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Liposomal 2-Methoxyestradiol Nanoparticles for Treatment of Uterine Leiomyoma in a Patient-Derived Xenograft Mouse Model.
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Liposomal doxorubicin increases radiofrequency ablation-induced tumor destruction by increasing cellular oxidative and nitrative stress and accelerating apoptotic pathways.
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Lipotropes enhance the anti-proliferative effect of chemotherapeutic drugs in MCF-7 human breast cancer cells.
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Lipoxin A4 protects rat skin flaps against ischemia-reperfusion injury through inhibiting cell apoptosis and inflammatory response induced by endoplasmic reticulum stress.
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Liraglutide ameliorates cardiotoxicity induced by doxorubicin in rats through the Akt/GSK-3? signaling pathway.
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Lithocarpus Polystachyus Rehd Leaf Aqueous Extract Inhibits Human Breast Cancer Growth In Vitro and In Vivo.
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Liver Injury and Tumor-Inhibiting Effect of Sequential Transcatheter Arterial Chemoembolization and Portal Venous Embolization on Rabbit VX2 Liver Carcinoma.
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Livin and caspase-3 expression are negatively correlated in cervical squamous cell cancer.
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Lixisenatide, a novel GLP-1 analog, protects against cerebral ischemia/reperfusion injury in diabetic rats.
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LncRNA NEAT1 regulates cervical carcinoma proliferation and invasion by targeting AKT/PI3K.
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LncRNA PCAT6 regulates the progression of pituitary adenomas by regulating the miR-139-3p/BRD4 axis.
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LncRNA SNHG15 Knockdown Protects Against OGD/R-Induced Neuron Injury by Downregulating TP53INP1 Expression via Binding to miR-455-3p.
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LncRNA THUMPD3-AS1 enhances the proliferation and inflammatory response of chondrocytes in osteoarthritis.
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LncRNA TUG1 acts as a tumor suppressor in human glioma by promoting cell apoptosis.
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Loading of doxorubicin and thymoquinone with F2 gel nanofibers improves the antitumor activity and ameliorates doxorubicin-associated nephrotoxicity.
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Local ablation of gastric cancer by reconstituted apolipoprotein B lipoparticles carrying epigenetic drugs.
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Localized therapy using anti-PD-L1 anchored and NIR-responsive hollow gold nanoshell (HGNS) loaded with doxorubicin (DOX) for the treatment of locally advanced melanoma.
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Location in the large bowel influences the APC mutations observed in FAP adenomas.
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Long noncoding RNA hypoxia-inducible factor 1 alpha-antisense RNA 1 promotes tumor necrosis factor-?-induced apoptosis through caspase 3 in Kupffer cells.
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Long noncoding RNA LINC00662-miR-15b-5p mediated GPR120 dysregulation contributes to osteoarthritis.
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Long-term fluorescence lifetime imaging of a genetically encoded sensor for caspase-3 activity in mouse tumor xenografts.
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Loss of caspase-3 sensitizes colon cancer cells to genotoxic stress via RIP1-dependent necrosis.
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Loss of p75 neurotrophin receptor expression accompanies malignant progression to human and murine retinoblastoma.
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Loss of programmed cell death 10 activates tumor cells and leads to temozolomide-resistance in glioblastoma.
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Loss of RUNX3 expression significantly affects the clinical outcome of gastric cancer patients and its restoration causes drastic suppression of tumor growth and metastasis.
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Low carbohydrate diets containing soy protein and fish oil slow the growth of established NNK-induced lung tumors.
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Low concentration of chloroquine enhanced efficacy of cisplatin in the treatment of human ovarian cancer dependent on autophagy.
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Low concentrations of trichosanthin induce apoptosis and cell cycle arrest via c-Jun N-terminal protein kinase/mitogen-activated protein kinase activation.
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Low dose radiation increased the therapeutic efficacy of cyclophosphamide on S(180) sarcoma bearing mice.
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Low levels of Caspase-3 predict favourable response to 5FU-based chemotherapy in advanced colorectal cancer: Caspase-3 inhibition as a therapeutic approach.
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Low-Dose Metformin Reprograms the Tumor Immune Microenvironment in Human Esophageal Cancer: Results of a Phase II Clinical Trial.
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Low-dose naltrexone inhibits colorectal cancer progression and promotes apoptosis by increasing M1-type macrophages and activating the Bax/Bcl-2/caspase-3/PARP pathway.
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Lowering Etoposide Doses Shifts Cell Demise From Caspase-Dependent to Differentiation and Caspase-3-Independent Apoptosis via DNA Damage Response, Inducing AML Culture Extinction.
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LPS-induced TNF? factor (LITAF) in the snail Cipangopaludina chinensis: gene cloning and its apoptotic effect on NCI-H446 cells.
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Lung cancer in mice induced by the jaagsiekte sheep retrovirus envelope protein is not maintained by rare cancer stem cells, but tumorigenicity does correlate with Wnt pathway activation.
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Luteolin and 5-flurouracil act synergistically to induce cellular weapons in experimentally induced Solid Ehrlich Carcinoma: Realistic role of P53; a guardian fights in a cellular battle.
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Luteolin and Gemcitabine Protect Against Pancreatic Cancer in an Orthotopic Mouse Model.
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Luteolin protects against testicular injury induced by lead acetate by activating the Nrf2/HO-1 pathway.
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Ly6E/K Signaling to TGF? Promotes Breast Cancer Progression, Immune Escape, and Drug Resistance.
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Lycopene abrogates A?(1-42)-mediated neuroinflammatory cascade in an experimental model of Alzheimer's disease.
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Lycopene attenuates aluminum-induced hippocampal lesions by inhibiting oxidative stress-mediated inflammation and apoptosis in the rat.
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Lycopene supplementation protects vascular dementia gerbils against the impairment of learning and memory.
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Lysine 53 Acetylation of Cytochrome c in Prostate Cancer: Warburg Metabolism and Evasion of Apoptosis.
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Lysionotin induces apoptosis of hepatocellular carcinoma cells via caspase-3 mediated mitochondrial pathway.
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Lysosomal and mitochondrial permeabilization mediates zinc(II) cationic phthalocyanine phototoxicity.
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M1 and M2 macrophages derived from THP-1 cells differentially modulate the response of cancer cells to etoposide.
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M1 macrophage-derived exosome-encapsulated cisplatin can enhance its anti-lung cancer effect.
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M867, a novel selective inhibitor of caspase-3 enhances cell death and extends tumor growth delay in irradiated lung cancer models.
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Macrophage inflammatory protein-2 promotes angiogenesis, cell migration, and tumor growth in hepatic metastasis.
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Macrophage migration inhibitory factor siRNA inhibits hepatic metastases of colorectal cancer cells.
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Macrophages mediate gemcitabine resistance of pancreatic adenocarcinoma by upregulating cytidine deaminase.
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Magnetic nanoparticle-mediated hyperthermia therapy induces tumour growth inhibition by apoptosis and Hsp90/AKT modulation.
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Magnetic resonance imaging assessment of effective ablated volume following high intensity focused ultrasound.
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Malaysian Propolis and Metformin Synergistically Mitigate Kidney Oxidative Stress and Inflammation in Streptozotocin-Induced Diabetic Rats.
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Malaysian propolis, metformin and their combination, exert hepatoprotective effect in streptozotocin-induced diabetic rats.
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Manganese suppresses oxidative stress, inflammation and caspase-3 activation in rats exposed to chlorpyrifos.
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MAPT (Tau) expression is a biomarker for an increased rate of survival in pediatric neuroblastoma.
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Marchantin C, a novel microtubule inhibitor from liverwort with anti-tumor activity both in vivo and in vitro.
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Marine guanidine alkaloids crambescidins inhibit tumor growth and activate intrinsic apoptotic signaling inducing tumor regression in a colorectal carcinoma zebrafish xenograft model.
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Marked suppression of tumor growth by FTY720 in a rat liver tumor model: the significance of down-regulation of cell survival Akt pathway.
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Mast cell stabilizer modulates Sirt1/Nrf2/TNF pathway and inhibits oxidative stress, inflammation, and apoptosis in rat model of cyclophosphamide hepatotoxicity.
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Maternal N-acetyl-cysteine prevents neonatal brain injury associated with necrotizing enterocolitis in a rat model.
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Maternal pomegranate juice attenuates maternal inflammation-induced fetal brain injury by inhibition of apoptosis, neuronal nitric oxide synthase, and NF-?B in a rat model.
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Matrine induces apoptosis in multiple colorectal cancer cell lines in vitro and inhibits tumour growth with minimum side effects in vivo via Bcl-2 and caspase-3.
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Matrine inhibits diethylnitrosamine-induced HCC proliferation in rats through inducing apoptosis via p53, Bax-dependent caspase-3 activation pathway and down-regulating MLCK overexpression.
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mda-7/IL-24 induces apoptosis in human GBC-SD gallbladder carcinoma cells via mitochondrial apoptotic pathway.
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MDA7 combined with targeted attenuated Salmonella vector SL7207/pBud-VP3 inhibited growth of gastric cancer cells.
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MDR1 and cytochrome P450 gene-expression profiles as markers of chemosensitivity in human chronic myelogenous leukemia cells treated with cisplatin and Ru(III) metallocomplexes.
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Mechanical deformation induced apoptosis in human proximal renal tubular epithelial cells is caspase dependent.
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Mechanism of retinoblastoma tumor cell death after focal chemotherapy, radiation, and vascular targeting therapy in a mouse model.
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Mechanisms involved in the possible nephroprotective effect of rutin and low dose ? irradiation against cisplatin-induced nephropathy in rats.
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Mechanisms of autophagy and apoptosis mediated by JAK2 signaling pathway after spinal cord injury of rats.
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Mechanisms of Cell Killing Response from Low Linear Energy Transfer (LET) Radiation Originating from (177)Lu Radioimmunotherapy Targeting Disseminated Intraperitoneal Tumor Xenografts.
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Mechanisms of microglia-mediated neurotoxicity in a new model of the stroke penumbra.
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Mechanisms of naringenin-induced apoptotic cascade in cancer cells: involvement of estrogen receptor alpha and beta signalling.
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Mechanisms of Yangjing Capsule in Leydig Cell Apoptosis and Testosterone Synthesis via Promoting StAR Expression.
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Mechanisms underlying the promotion of functional recovery by deferoxamine after spinal cord injury in rats.
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Mechanisms underlying the protective effect of leukotriene receptor antagonist montelukast against doxorubicin induced testicular injury in rats.
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Melanocortin MC? receptor agonists counteract late inflammatory and apoptotic responses and improve neuronal functionality after cerebral ischemia.
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Melanocortins counteract inflammatory and apoptotic responses to prolonged myocardial ischemia/reperfusion through a vagus nerve-mediated mechanism.
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Melanoma differentiation associated gene-7/interleukin-24 induces caspase-3 denitrosylation to facilitate the activation of cancer cell apoptosis.
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Melatonin alleviates liver steatosis induced by prenatal dexamethasone exposure and postnatal high-fat diet.
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Melatonin and IL-25 modulate apoptosis and angiogenesis mediators in metastatic (CF-41) and non-metastatic (CMT-U229) canine mammary tumour cells.
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Melatonin inhibits cholangiocarcinoma and reduces liver injury in Opisthorchis viverrini-infected and N-nitrosodimethylamine-treated hamsters.
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Melatonin reduces bacterial translocation and apoptosis in trinitrobenzene sulphonic acid-induced colitis of rats.
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Melatonin reduces pancreatic tumor cell viability by altering mitochondrial physiology.
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Membrane Androgen Receptor ZIP9 Induces Croaker Ovarian Cell Apoptosis via Stimulatory G Protein Alpha Subunit and MAP Kinase Signaling.
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Mertensene, a Halogenated Monoterpene, Induces G2/M Cell Cycle Arrest and Caspase Dependent Apoptosis of Human Colon Adenocarcinoma HT29 Cell Line through the Modulation of ERK-1/-2, AKT and NF-?B Signaling.
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Mesenchymal stem cells therapy enhances the efficacy of pregabalin and prevents its motor impairment in paclitaxel-induced neuropathy in rats: Role of Notch1 receptor and JAK/STAT signaling pathway.
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Mesenchymal stem cells with rhBMP-2 inhibits the growth of canine osteosarcoma cells.
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Meso-dihydroguaiaretic acid induces apoptosis and inhibits cell migration via p38 activation and EGFR/Src/intergrin ?3 downregulation in breast cancer cells.
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Mesoporous silica integrated with Fe3O4 and palmitoyl ascorbate as a new nano-Fenton reactor for amplified tumor oxidation therapy.
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Metabolic phenotype and adipose tissue inflammation in patients with chronic obstructive pulmonary disease.
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Metallic gold reduces TNFalpha expression, oxidative DNA damage and pro-apoptotic signals after experimental brain injury.
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Metallothionein induction reduces caspase-3 activity and TNFalpha levels with preservation of cognitive function and intact hippocampal neurons in carmustine-treated rats.
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Metastatic Cells Can Escape the Proapoptotic Effects of TNF-? through Increased Autocrine IL-6/STAT3 Signaling.
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Metastatic osteosarcoma induced by inactivation of Rb and p53 in the osteoblast lineage.
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Metformin and melatonin improve histopathological outcome of NMU-induced mammary tumors in rats.
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Metformin and melatonin inhibit DMBA-induced mammary tumorigenesis in rats fed a high-fat diet.
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Metformin and trimetazidine ameliorate diabetes-induced cognitive impediment in status epileptic rats.
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Metformin Attenuates Ischemia-reperfusion Injury of Fatty Liver in Rats Through Inhibition of the TLR4/NF-?B Axis
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Metformin potentiates the anticancer activities of gemcitabine and cisplatin against cholangiocarcinoma cells in vitro and in vivo.
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METH-Induced Neurotoxicity Is Alleviated by Lactulose Pretreatment Through Suppressing Oxidative Stress and Neuroinflammation in Rat Striatum.
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Methods for simultaneous measurement of apoptosis and cell surface phenotype of epithelial cells in effusions by flow cytometry.
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METTL14 Overexpression Promotes Osteosarcoma Cell Apoptosis and Slows Tumor Progression via Caspase 3 Activation.
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Micelle-encapsulated thiostrepton as an effective nanomedicine for inhibiting tumor growth and for suppressing FOXM1 in human xenografts.
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Micro RNA 34a and Let-7a Expression in Human Breast Cancers is Associated with Apoptotic Expression Genes.
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Microparticles generated during chronic cerebral ischemia increase the permeability of microvascular endothelial barriers in vitro.
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Micropropagation Effect on the Anti-carcinogenic Activitiy of Polyphenolics from Mexican Oregano (Poliomintha glabrescens Gray) in Human Colon Cancer Cells HT-29.
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MicroRNA regulation of viral immunity, latency, and carcinogenesis of selected tumor viruses and HIV.
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MicroRNA-107 may regulate lung cancer cell proliferation and apoptosis by targeting TP53 regulated inhibitor of apoptosis 1.
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MicroRNA-140-5p inhibits salivary adenoid cystic carcinoma progression and metastasis via targeting survivin.
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MicroRNA-33-5p inhibits cholesterol efflux in vascular endothelial cells by regulating citrate synthase and ATP-binding cassette transporter A1.
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MicroRNA-34a suppresses aggressiveness of hepatocellular carcinoma by modulating E2F1, E2F3, and Caspase-3.
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MicroRNA-369 attenuates hypoxia-induced cardiomyocyte apoptosis and inflammation via targeting TRPV3.
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MicroRNA-378 promotes cell survival, tumor growth, and angiogenesis by targeting SuFu and Fus-1 expression.
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MicroRNA-421 Inhibits Apoptosis by Downregulating Caspase-3 in Human Colorectal Cancer.
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MicroRNA-520a-3p suppresses non-small-cell lung carcinoma by inhibition of High Mobility Group Box 1 (HMGB1).
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MicroRNA?34a expression affects breast cancer invasion in vitro and patient survival via downregulation of E2F1 and E2F3 expression.
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Midkine protects hepatocellular carcinoma cells against TRAIL-mediated apoptosis through down-regulation of caspase-3 activity.
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Mild hypothermia in rat with acute myocardial ischaemia-reperfusion injury complicating severe sepsis.
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Milk fat globule membrane isolate induces apoptosis in HT-29 human colon cancer cells.
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Minicapsules encapsulating nanoparticles for targeting, apoptosis induction and treatment of colon cancer.
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Minocycline neuroprotects, reduces microgliosis, and inhibits caspase protease expression early after spinal cord injury.
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MiR-146b-3p protects against AR42J cell injury in cerulein-induced acute pancreatitis model through targeting Anxa2.
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miR-152 functions as a tumor suppressor in colorectal cancer by targeting PIK3R3.
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miR-187-5p/apaf-1 axis was involved in oxidative stress-mediated apoptosis caused by ammonia via mitochondrial pathway in chicken livers.
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miR-202 Promotes Cell Apoptosis in Esophageal Squamous Cell Carcinoma by Targeting HSF2.
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miR-205-3p promotes proliferation and reduces apoptosis of breast cancer MCF-7 cells and is associated with poor prognosis of breast cancer patients.
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MiR-20b promotes osteocyte apoptosis in rats with steroid-induced necrosis of the femoral head through BMP signaling pathway.
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MiR-21 indicates poor prognosis in tongue squamous cell carcinomas as an apoptosis inhibitor.
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miR-21 promotes growth, invasion and migration of lung cancer cells by AKT/P-AKT/cleaved-caspase 3/MMP-2/MMP-9 signaling pathway.
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MiR-212 Attenuates MPP?-Induced Neuronal Damage by Targeting KLF4 in SH-SY5Y Cells.
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miR-224 Is Significantly Upregulated and Targets Caspase-3 and Caspase-7 During Colorectal Carcinogenesis.
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miR-34 inhibits growth and promotes apoptosis of osteosarcoma in nude mice through targetly regulating TGIF2 expression.
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miR-34b inhibits the migration/invasion and promotes apoptosis of non-small-cell lung cancer cells by YAF2.
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MiR-421 regulates apoptosis of BGC-823 gastric cancer cells by targeting caspase-3.
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MIR106A-5p upregulation suppresses autophagy and accelerates malignant phenotype in nasopharyngeal carcinoma.
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miRNA-21 Expression in the Serum of Elderly Patients with Acute Myocardial Infarction.
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miRNA-mediated apoptosis activation through TMEM 48 inhibition in A549 cell line.
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Mitigating effect of biotin against irradiation-induced cerebral cortical and hippocampal damage in the rat brain tissue.
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Mitochondria-targeted betulinic and ursolic acid derivatives: synthesis and anticancer activity.
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Mitochondrial dysfunction-induced apoptosis in breast carcinoma cells through a pH-dependent intracellular quercetin NDDS of PVPylated-TiO2NPs.
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Mitochondrial induced and self-monitored intrinsic apoptosis by antitumor theranostic prodrug: in vivo imaging and precise cancer treatment.
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Mitogen-activated protein kinase phosphatase-1 prevents lipopolysaccharide-induced apoptosis in immature rat intestinal epithelial cells.
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Mitogenic and antiapoptotic actions of hepatocyte growth factor through ERK, STAT3, and AKT in endothelial cells.
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Mitotic catastrophe triggered in human cancer cells by the viral protein apoptin.
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Mixed tocopherols prevent mammary tumorigenesis by inhibiting estrogen action and activating PPAR-gamma.
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MLH1 mismatch repair gene product is associated with apoptotic potential of urothelial bladder carcinomas.
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Moderate DNA hypomethylation suppresses intestinal tumorigenesis by promoting caspase-3 expression and apoptosis.
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Modification of IL-24 by tumor penetrating peptide iRGD enhanced its antitumor efficacy against non-small cell lung cancer.
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Modulated Electro-Hyperthermia Facilitates NK-Cell Infiltration and Growth Arrest of Human A2058 Melanoma in a Xenograft Model.
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Modulated Electro-Hyperthermia Induces a Prominent Local Stress Response and Growth Inhibition in Mouse Breast Cancer Isografts.
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Modulated Electro-Hyperthermia Resolves Radioresistance of Panc1 Pancreas Adenocarcinoma and Promotes DNA Damage and Apoptosis In Vitro.
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Modulating effect of lupeol on the expression pattern of apoptotic markers in 7, 12-dimethylbenz(a)anthracene induced oral carcinogenesis.
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Modulating NF-?B, MAPK, and PI3K/AKT signaling by ergothioneine attenuates iron overload-induced hepatocellular injury in rats.
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Modulation by budesonide of DNA methylation and mRNA expression in mouse lung tumors.
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Modulation by proinflammatory cytokines of Fas/Fas ligand-mediated apoptotic cell death of synovial cells in patients with rheumatoid arthritis (RA).
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Modulation of effector caspase cleavage determines response of breast and lung tumor cell lines to chemotherapy.
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Modulation of Gene-Expression Profiles Associated with Sodium Arsenite-Induced Cardiotoxicity by p-Coumaric Acid, a Common Dietary Polyphenol.
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Modulation of heme oxygenase-1 expression and activity affects streptozotocin-induced diabetic nephropathy in rats.
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Modulation of key signal transduction molecules by a novel peptide combination effective for the treatment of gastrointestinal carcinomas.
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Modulation of pro-apoptotic effects and mitochondrial potential on B16F10 cells by DODAC/PHO-S liposomes.
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Modulation of the Unfolded Protein Response by Tauroursodeoxycholic Acid Counteracts Apoptotic Cell Death and Fibrosis in a Mouse Model for Secondary Biliary Liver Fibrosis.
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Modulator effects of meloxicam against doxorubicin-induced nephrotoxicity in mice.
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Modulatory effects of perindopril on cisplatin-induced nephrotoxicity in mice: Implication of inflammatory cytokines and caspase-3 mediated apoptosis.
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Modulatory effects of some natural products on hepatotoxicity induced by combination of sodium valproate and paracetamol in rats.
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Molecular Action of Inflammation and Oxidative Stress in Hyperglycemic Rats: Effect of Different Concentrations of Pterocarpus marsupiums Extract.
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Molecular cloning and characterization of a novel caspase-3 variant that attenuates apoptosis induced by proteasome inhibition.
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Molecular design and anti-melanoma activity of a novel bullfrog antibacterial peptide RGD-chimera.
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Molecular Docking Analysis of Caspase-3 Activators as Potential Anticancer Agents.
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Molecular evidence of apoptotic death in malignant brain tumors including glioblastoma multiforme: upregulation of calpain and caspase-3.
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Molecular imaging of akt enables early prediction of response to molecular targeted therapy.
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Molecular imaging of therapeutic response to epidermal growth factor receptor blockade in colorectal cancer.
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Molecular mechanism of epigallocatechin-3-gallate in human esophageal squamous cell carcinoma in vitro and in vivo.
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Molecular mechanisms contributing to the protective effect of levosimendan in liver ischemia-reperfusion injury.
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Molecular predictors of human nervous system cancer responsiveness to enediyne chemotherapy.
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Molecular Targets and Mechanisms of Scutellariae radix-Coptidis rhizoma Drug Pair for the Treatment of Ulcerative Colitis Based on Network Pharmacology and Molecular Docking.
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Molecular, anatomical, and biochemical events associated with neurodegeneration in mice with Niemann-Pick type C disease.
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Molecularly Targeted Therapy of Human Hepatocellular Carcinoma Xenografts with Radio-iodinated Anti-VEGFR2 Murine-Human Chimeric Fab.
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Momordica charantia L. induces non-apoptotic cell death in human MDA-MB-436 breast and A549 lung cancer cells by disrupting energy metabolism and exacerbating reactive oxygen species' generation.
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Monitoring Apoptosis of Breast Cancer Xenograft After Paclitaxel Treatment With 99mTc-Labeled Duramycin SPECT/CT.
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Monitoring caspase-3 activation with a multimodality imaging sensor in living subjects.
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Monitoring of tumor response to chemotherapy in vivo by a novel small-molecule detector of apoptosis.
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Montelukast rescues primary neurons against A?1-42-induced toxicity through inhibiting CysLT1R-mediated NF-?B signaling.
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Morin protects against acrylamide-induced neurotoxicity in rats: an investigation into different signal pathways.
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Morinda citrifolia (Noni) Juice Suppresses A549 Human Lung Cancer Cells via Inhibiting AKT/Nuclear Factor-? B Signaling Pathway.
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Morphophenotypic characteristics of intralymphatic cancer and stromal cells susceptible to lymphogenic metastasis.
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Morusin inhibits human cervical cancer stem cell growth and migration through attenuation of NF-?B activity and apoptosis induction.
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MoS2-ZnO nanocomposites as highly functional agents for anti-angiogenic and anti-cancer theranostics.
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MRI Evaluation of the effects of Whole Brain Radiotherapy on Breast Cancer Brain Metastasis.
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mRNA Expression of Bax, Bcl-2, p53, Cathepsin B, Caspase-3 and Caspase-9 in the HepG2 Cell Line Following Induction by a Novel Monoclonal Ab Hep88 mAb: Cross-Talk for Paraptosis and Apoptosis.
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MT-4 suppresses resistant ovarian cancer growth through targeting tubulin and HSP27.
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mTOR, S6 and AKT expression in relation to proliferation and apoptosis/autophagy in glioma.
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Mullerian inhibiting substance suppresses tumor growth in the C3(1)T antigen transgenic mouse mammary carcinoma model.
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Multi-Förster Resonance Energy Transfer-Based Fluorescent Probe for Spatiotemporal Matrix Metalloproteinase-2 and Caspase-3 Imaging.
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Multi-targeted protection of acetaminophen-induced hepatotoxicity in mice by tannic acid.
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Multidrug resistance reversal effect of DMC derived from buds of Cleistocalyx operculatus in human hepatocellular tumor xenograft model.
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Multifunctional nanocarrier mediated co-delivery of doxorubicin and siRNA for synergistic enhancement of glioma apoptosis in rat.
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Multifunctional Thio-Stabilized Gold Nanoparticles for Near-Infrared Fluorescence Detection and Imaging of Activated Caspase-3.
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Multimodal Imaging Techniques to Evaluate the Anticancer Effect of Cold Atmospheric Pressure Plasma.
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Multiple effects of hyperbaric oxygen on the expression of HIF-1 alpha and apoptotic genes in a global ischemia-hypotension rat model.
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Multiple species of CPP32 and Mch2 are the major active caspases present in apoptotic cells.
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Myenteric plexuses atrophy in the vicinity of colorectal cancer tissue is not caused by apoptosis or necrosis.
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Myo-InositolTrisPyroPhosphate Treatment Leads to HIF-1? Suppression and Eradication of Early Hepatoma Tumors in Rats.
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Myristica fragrans seed extract reverses scopolamine-induced cortical injury via stimulation of HO-1 expression in male rats.
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Myrtol improves post-traumatic knee osteoarthritis by regulation of reactive oxygen species, transforming growth factor ?1 and apoptosis in a mouse model.
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Myrtucommulone from Myrtus communis induces apoptosis in cancer cells via the mitochondrial pathway involving caspase-9.
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MytiLec, a Mussel R-Type Lectin, Interacts with Surface Glycan Gb3 on Burkitt's Lymphoma Cells to Trigger Apoptosis through Multiple Pathways.
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N-(4-Hydroxyphenyl) Retinamide Potentiated Anti-tumor Efficacy of Genistein in Human Ewing's Sarcoma Xenografts.
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N-acetylcysteine administration confers lung protection in different phases of lung ischaemia-reperfusion injury.
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N-acetylcysteine attenuates ventilator-induced lung injury in an isolated and perfused rat lung model.
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N-Adamantyl-4-Methylthiazol-2-Amine Attenuates Glutamate-Induced Oxidative Stress and Inflammation in the Brain.
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N-Caffeoyltyramine arrests growth of U937 and Jurkat cells by inhibiting protein tyrosine phosphorylation and inducing caspase-3.
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Nano-chemotherapy using cationic liposome that strategically targets the cell membrane potential of pancreatic cancer cells with negative charge.
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Nano-Curcumin Protects Against Sodium Nitrite-Induced Lung Hypoxia Through Modulation of Mitogen-Activated Protein Kinases/c-Jun NH2-Terminal Kinase Signaling Pathway.
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Nanoconjugation: A Materials Approach to Enhance Epidermal Growth Factor Induced Apoptosis.
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Nanoelectroablation of Murine Tumors Triggers a CD8-Dependent Inhibition of Secondary Tumor Growth.
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Nanographene oxide-hyaluronic acid conjugate for photothermal ablation therapy of skin cancer.
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Nanomedicine-based paclitaxel induced apoptotic signaling pathways in A562 leukemia cancer cells.
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Nanomelanin Potentially Protects the Spleen from Radiotherapy-Associated Damage and Enhances Immunoactivity in Tumor-Bearing Mice.
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Naringenin improves the healing process of thermally-induced skin damage in rats.
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Naringenin pre-treatment inhibits neuroapoptosis and ameliorates cognitive impairment in rats exposed to isoflurane anesthesia by regulating the PI3/Akt/PTEN signalling pathway and suppressing NF-?B-mediated inflammation.
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Natural Infection with Rabies Virus: A Histopathological and Immunohistochemical Study of Human Brains.
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Natural killer cell-derived exosome-entrapped paclitaxel can enhance its anti-tumor effect.
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Natural product triptolide induces GSDME-mediated pyroptosis in head and neck cancer through suppressing mitochondrial hexokinase-??.
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Naturally occurring benzoic acid derivatives retard cancer cell growth by inhibiting histone deacetylases (HDAC).
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Nature and mechanisms of hepatocyte apoptosis induced by D-galactosamine/lipopolysaccharide challenge in mice.
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Navitoclax (ABT 263) and Bendamustine ± Rituximab Induce Enhanced Killing of Non-Hodgkin's Lymphoma Tumors in Vivo.
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Neem leaf preparation induces apoptosis of tumor cells by releasing cytotoxic cytokines from human peripheral blood mononuclear cells.
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Nephroprotective effect of saxagliptin against gentamicin-induced nephrotoxicity, emphasis on anti-oxidant, anti-inflammatory and anti-apoptic effects.
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Nephroprotective effect of telmisartan in rats with ischemia/reperfusion renal injury.
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Nephroprotective effects of chlorogenic acid against sodium arsenite-induced oxidative stress, inflammation, and apoptosis.
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Nephroprotective potential of carnitine against glycerol and contrast-induced kidney injury in rats through modulation of oxidative stress, proinflammatory cytokines, and apoptosis.
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Nesfatin-1 ameliorates testicular injury and supports gonadal function in rats induced with testis torsion.
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Network Pharmacology Analysis of Traditional Chinese Medicine Formula Shuang Di Shou Zhen Tablets Treating Nonexudative Age-Related Macular Degeneration.
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Network-Based Systems Analysis Explains Sequence-Dependent Synergism of Bortezomib and Vorinostat in Multiple Myeloma.
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Neurobehavioural and biochemical responses associated with exposure to binary waterborne mixtures of zinc and nickel in rats.
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Neuroblastoma chemotherapy can be augmented by immunotargeting O-acetyl-GD2 tumor-associated ganglioside.
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Neuroprotection by the Traditional Chinese Medicine, Tao-Hong-Si-Wu-Tang, against Middle Cerebral Artery Occlusion-Induced Cerebral Ischemia in Rats.
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Neuroprotection of netrin-1 on neurological recovery via Wnt/?-catenin signaling pathway after spinal cord injury.
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Neuroprotective effect of chlorogenic acid in global cerebral ischemia-reperfusion rat model.
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Neuroprotective Effect of Cinnamaldehyde on Secondary Brain Injury After Traumatic Brain Injury in a Rat Model.
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Neuroprotective effect of curcumin nanoparticles against rat model of status epilepticus induced by pilocarpine.
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Neuroprotective Effect of Electric Conduction Treatment on Hippocampus Cell Apoptosis in KA Induced Acute Temporal Lobe Epileptic Rats.
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Neuroprotective effect of ginger in the brain of streptozotocin-induced diabetic rats.
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Neuroprotective effect of heat shock protein 60 on matrine-suppressed microglial activation.
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Neuroprotective effect of l-theanine in a rat model of chronic constriction injury of sciatic nerve-induced neuropathic pain.
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Neuroprotective effect of melatonin against hypoxia-induced retinal ganglion cell death in neonatal rats.
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Neuroprotective effect of N-acetyl cysteine against streptozotocin-induced memory dysfunction and oxidative damage in rats.
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Neuroprotective Effect of Plasminogen Activator Inhibitor-1 Antagonist in the Rat Model of Mild Traumatic Brain Injury.
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Neuroprotective effects of bee venom acupuncture therapy against rotenone-induced oxidative stress and apoptosis.
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Neuroprotective effects of eugenol against aluminiuminduced toxicity in the rat brain.
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Neuroprotective effects of exogenous methane in a rat model of acute carbon monoxide poisoning.
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Neuroprotective effects of Ganoderma lucidum polysaccharides against traumatic spinal cord injury in rats.
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Neuroprotective Effects of Platonin, a Therapeutic Immunomodulating Medicine, on Traumatic Brain Injury in Mice after Controlled Cortical Impact.
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Neuroprotective Effects of Pregabalin Against Spinal Cord Ischemia-Reperfusion Injury in Rats.
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Neuroprotective effects of rosuvastatin against traumatic spinal cord injury in rats.
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Neuroprotective effects of the new Na channel blocker rs100642 in global ischemic brain injury.
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Neuroprotective effects of thymoquinone against spinal cord ischemia-reperfusion injury by attenuation of inflammation, oxidative stress, and apoptosis.
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Neuroprotective Effects of Xanthohumol, a Prenylated Flavonoid from Hops (Humulus lupulus), in Ischemic Stroke of Rats.
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Neuroprotective mechanisms of puerarin in middle cerebral artery occlusion-induced brain infarction in rats.
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Neuroprotective mechanisms of rutin for spinal cord injury through anti-oxidation and anti-inflammation and inhibition of p38 mitogen activated protein kinase pathway.
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Neuroprotective mechanisms of selenium against arsenic-induced behavioral impairments in rats.
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Neuroprotective potential of fisetin in an experimental model of spinal cord injury: via modulation of NF-?B/I?B? pathway.
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Neuroprotective role of galantamine with/without physical exercise in experimental autoimmune encephalomyelitis in rats.
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New (E)-1-alkyl-1H-benzo[d]imidazol-2-yl)methylene)indolin-2-ones: Synthesis, in vitro cytotoxicity evaluation and apoptosis inducing studies.
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New chalcone derivative exhibits antiproliferative potential by inducing G2/M cell cycle arrest, mitochondrial-mediated apoptosis and modulation of MAPK signalling pathway.
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New pathways driving the experimental hepatoprotective action of tempol (4-hydroxy-2,2,6,6-tetramethylpiperidine-1-oxyl) against acute hepatotoxicity.
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NF-?B pathway took part in the development of apoptosis mediated by miR-15a and oxidative stress via mitochondrial pathway in ammonia-treated chicken splenic lymphocytes.
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Nicotine-encapsulated poly(lactic-co-glycolic) acid nanoparticles improve neuroprotective efficacy against MPTP-induced parkinsonism.
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Nifedipine and nimodipine protect dopaminergic substantia nigra neurons against axotomy-induced cell death in rat vibrosections via modulating inflammatory responses.
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Nimbolide prevents myocardial damage by regulating cardiac biomarkers, antioxidant level, and apoptosis signaling against doxorubicin-induced cardiotoxicity in rats.
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NIR Stimulus-Responsive PdPt Bimetallic Nanoparticles for Drug Delivery and Chemo-Photothermal Therapy.
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NIR-triggered high-efficient photodynamic and chemo-cascade therapy using caspase-3 responsive functionalized upconversion nanoparticles.
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Nitric oxide protects human extravillous trophoblast cells from apoptosis by a cyclic GMP-dependent mechanism and independently of caspase 3 nitrosylation.
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Nitrogen Permease Regulator-Like-2 Exhibited Anti-Tumor Effects And Enhanced The Sensitivity Of Colorectal Cancer Cells To Oxaliplatin And 5-Fluorouracil.
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Nitrosative and oxidative stress induced heme oxygenase-1 accumulation in rat mesangial cells.
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NNK-induced DNA methyltransferase 1 in lung tumorigenesis in A/J mice and inhibitory effects of (-)-epigallocatechin-3-gallate.
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Nodal marginal zone lymphoma: a heterogeneous tumor: a comprehensive analysis of a series of 27 cases.
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Noninvasive imaging of apoptosis induced by adenovirus-mediated cancer gene therapy using a caspase-3 biosensor in living subjects.
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Novel ?-Carboline/Hydroxamic Acid Hybrids Targeting Both Histone Deacetylase and DNA Display High Anticancer Activity via Regulation of the p53 Signaling Pathway.
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Novel Bioinformatics-Based Approach for Proteomic Biomarkers Prediction of Calpain-2 &Caspase-3 Protease Fragmentation: Application to ?II-Spectrin Protein.
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Novel ent-Kaurane Diterpenoid from Rubus corchorifolius L. f. Inhibits Human Colon Cancer Cell Growth via Inducing Cell Cycle Arrest and Apoptosis.
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Novel FTS-diamine/cinnamic acid hybrids inhibit tumor cell proliferation and migration and promote apoptosis via blocking Ras-related signaling in vitro.
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Novel piperine-loaded Tween-integrated monoolein cubosomes as brain-targeted oral nanomedicine in Alzheimer's disease: pharmaceutical, biological, and toxicological studies.
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Novel Polymeric Hybrid Nanocarrier for Curcumin and Survivin shRNA Co-delivery Augments Tumor Penetration and Promotes Synergistic Tumor Suppression.
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Novel polysaccharide extracted from Sipunculus nudus inhibits HepG2 tumour growth in vivo by enhancing immune function and inducing tumour cell apoptosis.
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Novel proapoptotic agent SM-1 enhances the inhibitory effect of 5-fluorouracil on colorectal cancer cells in vitro and in vivo.
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Novel Resveratrol-Based Aspirin Prodrugs: Synthesis, Metabolism, and Anticancer Activity.
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Novel role of kallistatin in vascular repair by promoting mobility, viability, and function of endothelial progenitor cells.
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Novel targeted mtLivin nanoparticles treatment for disseminated diffuse large B-cell lymphoma.
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Novel tetrahydroacridine derivatives inhibit human lung adenocarcinoma cell growth by inducing G1 phase cell cycle arrest and apoptosis.
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NOX5-L can stimulate proliferation and apoptosis depending on its levels and cellular context, determining cancer cell susceptibility to cisplatin.
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Nuclear factor-kappaB mediates Kupffer cell apoptosis through transcriptional activation of Fas/FasL.
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Nuclear Respiratory Factor 1 (NRF1) Transcriptional Activity-Driven Gene Signature Association with Severity of Astrocytoma and Poor Prognosis of Glioblastoma.
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Nucleus pulposus-induced apoptosis in dorsal root ganglion following experimental disc herniation in rats.
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NVP-LDE-225 (Erismodegib) inhibits epithelial-mesenchymal transition and human prostate cancer stem cell growth in NOD/SCID IL2R? null mice by regulating Bmi-1 and microRNA-128.
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Oct-4 expression maintained cancer stem-like properties in lung cancer-derived CD133-positive cells.
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Octreotide promotes apoptosis in human somatotroph tumor cells by activating somatostatin receptor type 2.
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OMP31 of Brucella melitensis 16M impairs the apoptosis of macrophages triggered by TNF-?.
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On the protective effect of omega-3 against propionic acid-induced neurotoxicity in rat pups.
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Oncogenic miR-137 contributes to cisplatin resistance via repressing CASP3 in lung adenocarcinoma.
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Oncogenic role of miR-155 in anaplastic large cell lymphoma lacking the t(2;5) translocation.
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Oncolytic Newcastle disease virus delivered by Mesenchymal stem cells-engineered system enhances the therapeutic effects altering tumor microenvironment.
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Oncolytic vesicular stomatitis virus induces apoptosis in U87 glioblastoma cells by a type II death receptor mechanism and induces cell death and tumor clearance in vivo.
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Optical imaging and anticancer chemotherapy through carbon dot created hollow mesoporous silica nanoparticles.
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Optical metabolic imaging identifies glycolytic levels, subtypes, and early-treatment response in breast cancer.
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Optimization of boron neutron capture therapy for the treatment of undifferentiated thyroid cancer.
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Oral administration of benzyl-isothiocyanate inhibits solid tumor growth and lung metastasis of 4T1 murine mammary carcinoma cells in BALB/c mice.
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Oral glutamine protects against acute doxorubicin-induced cardiotoxicity of tumor-bearing rats.
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Oral silibinin inhibits in vivo human bladder tumor xenograft growth involving down-regulation of survivin.
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Oral treatment of the TRAMP mice with doxazosin suppresses prostate tumor growth and metastasis.
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Oral treatment with herbal formula B307 alleviates cardiac failure in aging R6/2 mice with Huntington's disease via suppressing oxidative stress, inflammation, and apoptosis.
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Oral treatment with the herbal formula B307 alleviates cardiac toxicity in doxorubicin-treated mice via suppressing oxidative stress, inflammation, and apoptosis.
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Orally administered green tea polyphenols prevent ultraviolet radiation-induced skin cancer in mice through activation of cytotoxic T cells and inhibition of angiogenesis in tumors.
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Oregano demonstrates distinct tumour-suppressive effects in the breast carcinoma model.
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Organotypic slice cultures of pancreatic ductal adenocarcinoma preserve the tumor microenvironment and provide a platform for drug response.
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Oridonin Enhances Radiation-Induced Cell Death by Promoting DNA Damage in Non-Small Cell Lung Cancer Cells.
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Outer membrane proteins of wild-type and intimin-deficient enteropathogenic Escherichia coli induce Hep-2 cell death through intrinsic and extrinsic pathways of apoptosis.
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Outgrowth of human liver metastases after resection of the primary colorectal tumor: a shift in the balance between apoptosis and proliferation.
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Ovarian tumor initiating cell populations persist following paclitaxel and carboplatin chemotherapy treatment in vivo.
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Over-expression of calpastatin inhibits calpain activation and attenuates myocardial dysfunction during endotoxaemia.
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Overexpressed targeting protein for Xklp2 (TPX2) serves as a promising prognostic marker and therapeutic target for gastric cancer.
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Overexpression of Bcl-2 inhibits nuclear localization of annexin I during tumor necrosis factor-alpha-mediated apoptosis in porcine renal LLC-PK1 cells.
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Overexpression of cellular repressor of E1A-stimulated genes inhibits TNF-?-induced apoptosis via NF-?B in mesenchymal stem cells.
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Overexpression of DLC-1 induces cell apoptosis and proliferation inhibition in the renal cell carcinoma.
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Overexpression of IRS-4 Correlates with Procaspase 3 Levels in Tumoural Tissue of Patients with Colorectal Cancer.
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Overexpression of modified human TR?1 suppresses the growth of hepatocarcinoma SK-hep1 cells in vitro and in xenograft models.
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Oxidative stress is related to the formation of Antoni B patterns and eosinophilic hyaline droplets in schwannomas.
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Oxygen-charged HTK-F6H8 emulsion reduces ischemia-Reperfusion injury in kidneys from brain-dead Pigs.
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Oxytocin mediates the beneficial effects of the exercise training on breast cancer.
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P-glycoprotein expression does not change the apoptotic pathway induced by curcumin in HL-60 cells.
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P21 activated kinase-1 mediates transforming growth factor ?1-induced prostate cancer cell epithelial to mesenchymal transition.
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p38 mitogen activated protein kinase mediates both death signaling and functional depression in the heart.
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P53 mutation analysis of colorectal liver metastases: relation to actual survival, angiogenic status, and p53 overexpression.
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p53 signaling is involved in leptin-induced growth of hepatic and breast cancer cells.
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P73 and caspase-cleaved p73 fragments localize to mitochondria and augment TRAIL-induced apoptosis.
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PAC-1 activates procaspase-3 in vitro through relief of zinc-mediated inhibition.
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PAC-1 and its derivative WF-210 Inhibit Angiogenesis by inhibiting VEGF/VEGFR pathway.
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PACAP and a novel stable analog protect rat brain from ischemia: Insight into the mechanisms of action.
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Paclitaxel induces apoptosis in leukemia cells through a JNK activation-dependent pathway.
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Paeoniflorin attenuates hepatic ischemia/reperfusion injury via anti-oxidative, anti-inflammatory and anti-apoptotic pathways.
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Paeoniflorin targets apoptosis and ameliorates fibrosis in murine schistosomiasis mansoni: A novel insight.
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Paeonol inhibits proliferation and induces cell apoptosis of human T24 and 5637 bladder cancer cells in vitro and in vivo.
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Pain Input After Spinal Cord Injury (SCI) Undermines Long-Term Recovery and Engages Signal Pathways That Promote Cell Death.
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Pancreatic damage induced by cigarette smoke: the specific pathological effects of cigarette smoke in the rat model.
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Pannus inflammation in sacroiliitis following immune pathological injury and radiological structural damage: a study of 193 patients with spondyloarthritis.
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Paradoxical cardiotoxicity of intraperitoneally-injected epigallocatechin gallate preparation in diabetic mice.
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Paradoxical effects of T-cadherin on squamous cell carcinoma: up- and down-regulation increase xenograft growth by distinct mechanisms.
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Parasporin-2 from a New Bacillus thuringiensis 4R2 Strain Induces Caspases Activation and Apoptosis in Human Cancer Cells.
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Paroxetine combined with fluorouracil plays a therapeutic role in mouse models of colorectal cancer with depression through inhibiting IL-22 expression to regulate the MAPK signaling pathway.
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Parthenolide Induces Reactive Oxygen Species-Mediated Autophagic Cell Death in Human Osteosarcoma Cells.
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Pathway-focused gene expression profiles and immunohistochemistry detection identify contrasting association of caspase 3 (CASP3) expression with prognosis in pediatric classical Hodgkin lymphoma.
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PCC0208023, a potent SHP2 allosteric inhibitor, imparts an antitumor effect against KRAS mutant colorectal cancer.
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Pediatric and adult glioblastoma radiosensitization induced by PI3K/mTOR inhibition causes early metabolic alterations detected by nuclear magnetic resonance spectroscopy.
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Pegylated folate and peptide-decorated graphene oxide nanovehicle for in vivo targeted delivery of anticancer drugs and therapeutic self-monitoring.
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PEGylated lipid bilayer-supported mesoporous silica nanoparticle composite for synergistic co-delivery of axitinib and celastrol in multi-targeted cancer therapy.
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Pegylated liquisomes: A novel combined passive targeting nanoplatform of L-carnosine for breast cancer.
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Penehyclidine hydrochloride exerts protective effects in rats with acute lung injury via the Fas/FasL signaling pathway.
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Penfluridol suppresses glioblastoma tumor growth by Akt-mediated inhibition of GLI1.
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Perfluorononanoic acid-induced apoptosis in rat spleen involves oxidative stress and the activation of caspase-independent death pathway.
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Perilaldehyde activates AMP-activated protein kinase to suppress the growth of gastric cancer via induction of autophagy.
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Peroxiredoxin I deficiency increases keratinocyte apoptosis in a skin tumor model via the ROS-p38 MAPK pathway.
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Peroxisome proliferator-activated receptor beta (delta)-dependent regulation of ubiquitin C expression contributes to attenuation of skin carcinogenesis.
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pH-Induced Folding of the Caspase-Cleaved Par-4 Tumor Suppressor: Evidence of Structure Outside of the Coiled Coil Domain.
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Phagocytosis (cannibalism) of apoptotic neutrophils by tumor cells in gastric micropapillary carcinomas.
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Pharmacodynamic markers and clinical results from the phase 2 study of the SMAC mimetic birinapant in women with relapsed platinum-resistant or -refractory epithelial ovarian cancer.
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Pharmacodynamics effects of CDK4/6 inhibitor LEE011 (ribociclib) in high-risk, localised prostate cancer: a study protocol for a randomised controlled phase II trial (LEEP study: LEE011 in high-risk, localised Prostate cancer).
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Pharmacodynamics of cisplatin-loaded PLGA nanoparticles administered to tumor-bearing mice.
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Pharmacokinetic and phototherapeutic studies of monocationic methoxyphenylporphyrin derivative.
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Pharmacokinetics, Tissue Localization, Toxicity, and Treatment Efficacy in the First Small Animal (Rabbit) Model of Intra-Arterial Chemotherapy for Retinoblastoma.
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Pharmacologic blockade of FAK autophosphorylation decreases human glioblastoma tumor growth and synergizes with temozolomide.
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PHD3 regulates differentiation, tumour growth and angiogenesis in pancreatic cancer.
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Phellinus linteus extract sensitizes advanced prostate cancer cells to apoptosis in athymic nude mice.
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Phenazine-1-carboxamide (PCN) from Pseudomonas sp. strain PUP6 selectively induced apoptosis in lung (A549) and breast (MDA MB-231) cancer cells by inhibition of antiapoptotic Bcl-2 family proteins.
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Phenethyl isothiocyanate potentiates anti-tumour effect of doxorubicin through Akt-dependent pathway.
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Phenformin has anti-tumorigenic effects in human ovarian cancer cells and in an orthotopic mouse model of serous ovarian cancer.
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Phenolic Compounds of Catalpa speciosa, Taxus cuspidate, and Magnolia acuminata have Antioxidant and Anticancer Activity.
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Phenotypic characterization of BRCA1 and BRCA2 tumors based in a tissue microarray study with 37 immunohistochemical markers.
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Phenoxazine derivative, 2-amino-4,4alpha-dihydro-4alpha,7-dimethyl-3H-phenoxazine-3-one suppresses growth of human retinoblastoma cell line Y79 in vitro and in vivo.
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Phorate-induced oxidative stress, DNA damage and transcriptional activation of p53 and caspase genes in male Wistar rats.
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Phorbol Esters from Jatropha Meal Triggered Apoptosis, Activated PKC-?, Caspase-3 Proteins and Down-Regulated the Proto-Oncogenes in MCF-7 and HeLa Cancer Cell Lines.
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Phosphatidylinositol 3-kinases inhibitor LY294002 potentiates the cytotoxic effects of doxorubicin, vincristine, and etoposide in a panel of cancer cell lines.
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Phosphoribosylpyrophosphate Synthetase 1 Knockdown Suppresses Tumor Formation of Glioma CD133+ Cells Through Upregulating Cell Apoptosis.
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Phosphorylated c-MYC expression in Alzheimer disease, Pick's disease, progressive supranuclear palsy and corticobasal degeneration.
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Phosphorylated ERalpha, HIF-1alpha, and MAPK signaling as predictors of primary endocrine treatment response and resistance in patients with breast cancer.
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Phosphorylated histone H3, Ki-67, p21, fatty acid synthase, and cleaved caspase-3 expression in benign and atypical granular cell tumors.
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Phosphorylation-regulated cleavage of the tumor suppressor PTEN by caspase-3: implications for the control of protein stability and PTEN-protein interactions.
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Photo-click construction of a targetable and activatable two-photon probe imaging protease in apoptosis.
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Photobiomodulation therapy improved functional recovery and overexpression of interleukins-10 after contusion spinal cord injury in rats.
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Photodynamic therapy agent with a built-in apoptosis sensor for evaluating its own therapeutic outcome in situ.
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Photodynamic therapy with the phthalocyanine photosensitizer Pc 4 of SW480 human colon cancer xenografts in athymic mice.
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Photodynamic therapy with the phthalocyanine photosensitizer Pc 4: The case experience with preclinical mechanistic and early clinical-translational studies.
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Photothermal therapy mediated by gum Arabic-conjugated gold nanoparticles suppresses liver preneoplastic lesions in mice.
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Physalin B from Physalis angulata triggers the NOXA-related apoptosis pathway of human melanoma A375 cells.
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Physalis alkekengi L. Extract Reduces the Oxidative Stress, Inflammation and Apoptosis in Endothelial Vascular Cells Exposed to Hyperglycemia.
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Physical and cognitive training attenuate hippocampal ischemia-induced memory impairments in rat.
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Pilot in vitro and in vivo study on a mouse model to evaluate the safety of transcutaneous low-frequency electrical nerve stimulation on cervical cancer patients.
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Pinocembrin ex vivo preconditioning improves the therapeutic efficacy of endothelial progenitor cells in monocrotaline-induced pulmonary hypertension in rats.
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Pinpointing differences in cisplatin-induced apoptosis in adherent and non-adherent cancer cells.
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Pinus Roxburghii essential oil anticancer activity and chemical composition evaluation.
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Pivotal role of TLR4 receptors in alcohol-induced neuroinflammation and brain damage.
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Platelet-activating factor receptor (PAF-R)-dependent pathways control tumour growth and tumour response to chemotherapy.
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Platinum nanoparticles induced genotoxicity and apoptotic activity in human normal and cancer hepatic cells via oxidative stress-mediated Bax/Bcl-2 and caspase-3 expression.
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Platinum(II) Iodido Complexes of 7-Azaindoles with Significant Antiproliferative Effects: An Old Story Revisited with Unexpected Outcomes.
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Pleurotus nebrodensis polysaccharide(PN50G) evokes A549 cell apoptosis by the ROS/AMPK/PI3K/AKT/mTOR pathway to suppress tumor growth.
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PND-1186 FAK inhibitor selectively promotes tumor cell apoptosis in three-dimensional environments.
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Pogostone Induces Autophagy and Apoptosis Involving PI3K/Akt/mTOR Axis in Human Colorectal Carcinoma HCT116 cells.
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Polo-like kinase 1 contributes to the tumorigenicity of BEL-7402 hepatoma cells via regulation of Survivin expression.
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Poly C Binding Protein 1 Regulates p62/SQSTM1 mRNA Stability and Autophagic Degradation to Repress Tumor Progression.
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Poly C binding protein 1 represses autophagy through downregulation of LC3B to promote tumor cell apoptosis in starvation.
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Poly-l-Lysine inhibits VEGF and c-Myc mediated tumor-angiogenesis and induces apoptosis in 2D and 3D tumor microenvironment of both MDA-MB-231 and B16F10 induced mice model.
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Polyamine depletion reduces TNFalpha/MG132-induced apoptosis in bone marrow stromal cells.
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Polycaprolactone/polysialic acid hybrid, multifunctional nanofiber scaffolds for treatment of spinal cord injury.
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Polyclonal rabbit anti-human ovarian cancer globulins inhibit tumor growth through apoptosis involving the caspase signaling.
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Polydatin Encapsulated Poly [Lactic-co-glycolic acid] Nanoformulation Counteract the 7,12-Dimethylbenz[a] Anthracene Mediated Experimental Carcinogenesis through the Inhibition of Cell Proliferation.
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Polydatin Increases Radiosensitivity by Inducing Apoptosis of Stem Cells in Colorectal Cancer.
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Polydatin inhibits cell proliferation, invasion and migration, and induces cell apoptosis in hepatocellular carcinoma.
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Polydatin protects against lipopolysaccharide-induced fulminant hepatic failure in D-galactosamine-sensitized mice.
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Polyethylene glycol inhibits intestinal neoplasia and induces epithelial apoptosis in Apc(min) mice.
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Polygonum cuspidatum stem extract (PSE) ameliorates dry eye disease by inhibiting inflammation and apoptosis.
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Polymer-lipid hybrid nanoparticles-based paclitaxel and etoposide combinations for the synergistic anticancer efficacy in osteosarcoma.
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Polymeric micelles for potentiated antiulcer and anticancer activities of naringin.
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Polymorphisms and haplotypes in the caspase-3, caspase-7, and caspase-8 genes and risk for endometrial cancer: a population-based, case-control study in a Chinese population.
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Polysaccharides Extracted from Rhizoma Pleionis Have Antitumor Properties In Vitro and in an H22 Mouse Hepatoma Ascites Model In Vivo.
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Polysaccharides from the peels of Citrus aurantifolia induce apoptosis in transplanted H22 cells in mice.
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Polyvalent Folate-Dendrimer-Coated Iron Oxide Theranostic Nanoparticles for Simultaneous Magnetic Resonance Imaging and Precise Cancer Cell Targeting.
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Pomegranate exerts chemoprevention of experimentally induced mammary tumorigenesis by suppression of cell proliferation and induction of apoptosis.
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Positron emission tomography imaging of drug-induced tumor apoptosis with a caspase-triggered nanoaggregation probe.
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Possible curative role of curcumin and silymarin against nephrotoxicity induced by gamma-rays in rats.
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Possible in vivo mechanisms involved in photodynamic therapy using tetrapyrrolic macrocycles.
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Possible interactions between the NS-1 protein and tumor necrosis factor alpha pathways in erythroid cell apoptosis induced by human parvovirus B19.
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Possible mechanisms of Leukoagglutinin induced apoptosis in human cells in vitro.
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Possible Protective Effect of Diacerein on Doxorubicin-Induced Nephrotoxicity in Rats.
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Possible role of apoptosis in the pathogenesis and clinical evolution of radicular cyst: an immunohistochemical study.
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Post-traumatic caspase-3 expression in the adjacent areas of growth plate injury site: a morphological study.
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Posttranslational and Therapeutic Control of Gasdermin-Mediated Pyroptosis and Inflammation.
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Potent Antitumor Activity of Oncolytic Adenovirus Expressing mda-7/IL-24 for Colorectal Cancer.
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Potent antitumor activity of oncolytic adenovirus expressing mda-7/IL-24 for colorectal cancer.
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Potent antitumor effect elicited by RGD-mda-7, an mda-7/IL-24 mutant, via targeting the integrin receptor of tumor cells.
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Potent inhibition of Lewis lung cancer growth by heyneanol A from the roots of Vitis amurensis through apoptotic and anti-angiogenic activities.
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Potential advantages of Chinese medicine Taohong Siwu Decoction () combined with tissue-plasminogen activator for alleviating middle cerebral artery occlusion-induced embolic stroke in rats.
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Potential anticancer activities of Rhus coriaria (sumac) extract against human cancer cell lines.
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Potential anticancer activity and mechanism of action of nanoformulated curcumin in experimental Ehrlich ascites carcinoma-bearing animals.
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Potential immunomodulatory and antioxidant effects of walnut Juglans regia vegetable oil against lead-mediated hepatic damage and their interaction with lipase activity in rats.
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Potential mechanism of cell death in the developing rat brain induced by propofol anesthesia.
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Potential Molecular Mechanisms of Plantain in the Treatment of Gout and Hyperuricemia Based on Network Pharmacology.
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Potential role of Notch1 signaling pathway in laryngeal squamous cell carcinoma cell line Hep-2 involving proliferation inhibition, cell cycle arrest, cell apoptosis, and cell migration.
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Potential small-molecule activators of caspase-7 identified using yeast-based caspase-3 and -7 screening assays.
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Precancerous stem cells have the potential for both benign and malignant differentiation.
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Preclinical activity of a novel multiple tyrosine kinase and aurora kinase inhibitor, ENMD-2076, against multiple myeloma.
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Preclinical colorectal cancer chemopreventive efficacy and p53-modulating activity of 3',4',5'-trimethoxyflavonol, a quercetin analogue.
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Preclinical evaluation of destruxin B as a novel Wnt signaling target suppressing proliferation and metastasis of colorectal cancer using non-invasive bioluminescence imaging.
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Preclinical evaluation of novel triphenylphosphonium salts with broad-spectrum activity.
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Preclinical studies identify non-apoptotic low-level caspase-3 as therapeutic target in pemphigus vulgaris.
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Preconditioning Exercise in Rats Attenuates Early Brain Injury Resulting from Subarachnoid Hemorrhage by Reducing Oxidative Stress, Inflammation, and Neuronal Apoptosis.
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Prediction of proapoptotic anticancer therapeutic response in vivo based on cell death visualization and TRAIL death ligand-receptor interaction.
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Prefrontal Cortex and Hippocampus Inflammation in Mice Fed High-Carbohydrate or High-Fat Diets.
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Pregabalin and lacosamide ameliorate paclitaxel-induced peripheral neuropathy via inhibition of JAK/STAT signaling pathway and Notch-1 receptor.
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Premortem autophagy determines the immunogenicity of chemotherapy-induced cancer cell death.
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Preoperative Somatostatin Analogue Treatment Might Trigger Apoptosis and Autophagy in Tumor Tissues of Patients with Acromegaly: A Pilot Study.
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Preparation and Characterization of Fe3O4@MTX Magnetic Nanoparticles for Thermochemotherapy of Primary Central Nervous System Lymphoma in vitro and in vivo.
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Preparation of two organoselenium compounds and their induction of apoptosis to SMMC-7221 cells.
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Preparation, Characterization and In-vitro Biological Evaluation of Novel Curcumin Derivatives as Cytotoxic and Apoptosis-Inducing Agents.
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Preparation, Optimization and In-Vitro Evaluation of Curcumin-Loaded Niosome@calcium Alginate Nanocarrier as a New Approach for Breast Cancer Treatment.
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Preponderance of cells with stem cell characteristics in metastasising mouse mammary tumours induced by deregulated EphB4 and ephrin-B2 expression.
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Pretreatment with insulin enhances anticancer functions of 5-fluorouracil in human esophageal and colonic cancer cells.
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Prevention of Barrett Esophagus and Esophageal Adenocarcinoma by Smoothened Inhibitor in a Rat Model of Gastroesophageal Reflux Disease.
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Preventive and therapeutic effects of oleuropein against carbon tetrachloride-induced liver damage in mice.
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Primula auriculata Extracts Exert Cytotoxic and Apoptotic Effects against HT-29 Human Colon Adenocarcinoma Cells.
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Pro-apoptotic activity of imidazole derivatives mediated by up-regulation of Bax and activation of CAD in Ehrlich Ascites Tumor cells.
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Pro-apoptotic effects of Kangfuxin on human stomach cancer cells and its underlying mechanism.
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Pro-apoptotic function of HBV X protein is mediated by interaction with c-FLIP and enhancement of death-inducing signal.
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Pro-apoptotic Sorafenib signaling in murine hepatocytes depends on malignancy and is associated with PUMA expression in vitro and in vivo.
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Probing the selective antitumor activity of 22-oxo-26-selenocyanocholestane derivatives.
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Procaspase-3 activation as an anti-cancer strategy: structure-activity relationship of procaspase-activating compound 1 (PAC-1) and its cellular co-localization with caspase-3.
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Procaspase-3 Overexpression in Cancer: A Paradoxical Observation with Therapeutic Potential.
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Progesterone and 1,25-dihydroxyvitamin D? inhibit endometrial cancer cell growth by upregulating semaphorin 3B and semaphorin 3F.
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Progesterone Inhibits the Growth of Human Neuroblastoma: In Vitro and In Vivo Evidence.
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Prognostic effect of activated EGFR expression in human colon carcinomas: comparison with EGFR status.
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Prognostic markers of low-grade squamous intraepithelial lesions: the role of topoisomerase IIalpha and active caspase-3.
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Prognostic significance of apoptotic cell death in bladder cancer: a tissue microarray study on 179 urothelial carcinomas from cystectomy specimens.
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Prognostic significance of caspase-3 expression in primary resected esophageal squamous cell carcinoma.
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Prognostic significance of micropapillary pattern in lung adenocarcinoma and expression of apoptosis-related markers: caspase-3, bcl-2, and p53.
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Prognostic value of Caspase-3 expression in cancers of digestive tract: a meta-analysis and systematic review.
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Prognostic value of inhibitors of apoptosis proteins (IAPs) and caspases in prostate cancer: caspase-3 forms and XIAP predict biochemical progression after radical prostatectomy.
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Prognostic value of microsatellite instability determined by immunohistochemical staining of hMSH2 and hMSH6 in urothelial carcinoma of the bladder.
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Programmed Cell Death 6 (PDCD6) Protein Interacts with Death-Associated Protein Kinase 1 (DAPk1): Additive Effect on Apoptosis via Caspase-3 Dependent Pathway
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Programmed cell death 6 (PDCD6) protein interacts with death-associated protein kinase 1 (DAPk1): additive effect on apoptosis via caspase-3 dependent pathway.
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Programming cell pyroptosis with biomimetic nanoparticles for solid tumor immunotherapy.
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Proliferation and apoptosis of tumour cells before and after neoadjuvant therapy for high-grade extremity sarcomas: divergent associations with tumour response and prognosis.
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Prolonged survival and delayed progression of pancreatic intraepithelial neoplasia in LSL-KrasG12D/+;Pdx-1-Cre mice by vitamin E ?-tocotrienol.
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Promotion of mitotic catastrophe via activation of PTEN by paclitaxel with supplement of mulberry water extract in bladder cancer cells.
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Prophylactic effects of ellagic acid and rosmarinic acid on doxorubicin-induced neurotoxicity in rats.
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Propolis ameliorates tumor Nerosis factor-?, nitric oxide levels, caspase-3 and nitric oxide synthase activities in Kainic acid mediated excitotoxicity in rat brain.
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Prostate cancer cell growth characteristics in serum and prostate-conditioned media from moderate-intensity exercise-trained healthy and tumor-bearing rats.
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Protease-activated receptor-1 (hPar1), a survival factor eliciting tumor progression.
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Proteasome inhibition with bortezomib induces cell death in GBM stem-like cells and temozolomide-resistant glioma cell lines, but stimulates GBM stem-like cells' VEGF production and angiogenesis.
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Protection by Bcl-2 against apoptotic but not autophagic cell death after photodynamic therapy.
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Protection of mitochondrial perturbation by human T-lymphotropic virus type 1 tax through induction of Bcl-xL expression.
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Protective effect and molecular mechanism of liquiritin on oxybuprocaine-induced apoptosis of human corneal endothelial cells.
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Protective effect of 5-HT7 receptor activation against glutamate-induced neurotoxicity in human neuroblastoma SH-SY5Y cells via antioxidative and antiapoptotic pathways.
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Protective effect of aqueous seed extract of Vitis Vinifera against oxidative stress, inflammation and apoptosis in the pancreas of adult male rats with diabetes mellitus.
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Protective effect of Coriandrum sativum extract against inflammation and apoptosis in liver ischemia reperfusion injury.
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Protective effect of dipeptidyl peptidase-4 inhibitors in testicular torsion/detorsion in rats: a possible role of HIF-1? and nitric oxide.
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Protective effect of epigallocatechin gallate, a major constituent of green tea, against renal ischemia-reperfusion injury in rats.
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Protective effect of irbesartan against doxorubicin-induced nephrotoxicity in rats: implication of AMPK, PI3K/Akt, and mTOR signaling pathways.
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Protective Effect of Naringenin against Lipopolysaccharide-Induced Acute Lung Injury in Rats.
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Protective effect of peroxisome proliferator activator receptor (PPAR)-? and -? ligands against methotrexate-induced nephrotoxicity.
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Protective effect of proanthocyanidins against doxorubicin-induced nephrotoxicity in rats.
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Protective effect of Rosuvastatin on Azithromycin induced cardiotoxicity in a rat model.
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Protective effect of Salvia miltiorrhiza and Carthamus tinctorius extract against lipopolysaccharide-induced liver injury.
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Protective effect of telmisartan treatment against arsenic-induced testicular toxicity in rats.
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Protective effect of the traditional Chinese medicine xuesaitong on intestinal ischemia-reperfusion injury in rats.
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Protective effect of vascular endothelial growth factor against cardiopulmonary bypass-associated acute kidney injury in beagles.
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Protective effect of zinc on N-methyl-N-nitrosourea and testosterone-induced prostatic intraepithelial neoplasia in the dorsolateral prostate of Sprague Dawley rats.
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Protective effects and mechanism of curcumin on myocardial injury induced by coronary microembolization.
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Protective effects of ?-casofensin, a bioactive peptide from bovine ?-casein, against indomethacin-induced intestinal lesions in rats.
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Protective effects of a free radical scavenger, MCI-186, on high-glucose-induced dysfunction of human dermal microvascular endothelial cells.
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Protective effects of Asiaticoside on acute liver injury induced by lipopolysaccharide/D-galactosamine in mice.
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Protective Effects of Carvedilol and Vitamin C against Azithromycin-Induced Cardiotoxicity in Rats via Decreasing ROS, IL1-?, and TNF-? Production and Inhibiting NF-?B and Caspase-3 Expression.
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Protective Effects of Irbesartan, an Angiotensin Receptor Blocker with PPAR? Agonistic Activity, against Estradiol Benzoate-Induced Endometrial Hyperplasia and Atypia in Female Rats via Modulation of TNF?/Survivin Pathway.
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Protective Effects of Luteolin on Lipopolysaccharide-Induced Acute Renal Injury in Mice.
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Protective effects of melanocortins on short-term changes in a rat model of traumatic brain injury*
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Protective effects of miR-155-5p silencing on IFN-?-induced apoptosis and inflammation in salivary gland epithelial cells.
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Protective effects of propofol on endotoxemia-induced acute kidney injury in rats.
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Protective effects of pterostilbene against acetaminophen-induced hepatotoxicity in rats.
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Protective effects of salidroside against acetaminophen-induced toxicity in mice.
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Protective effects of St. John's wort in the hepatic ischemia/reperfusion injury in rats.
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Protective effects of tannic acid on pressure overload-induced cardiac hypertrophy and underlying mechanisms in rats.
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Protective effects of the ethanolic extract of Melia toosendan fruit against colon cancer.
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Protective Effects of the Third Generation Vasodilatory ?eta - Blocker Nebivolol against D-Galactosamine - Induced Hepatorenal Syndrome in Rats.
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Protective Effects of [6]-Paradol on Histological Lesions and Immunohistochemical Gene Expression in DMBA Induced Hamster Buccal Pouch Carcinogenesis.
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Protective Role of Loranthus regularis against Liver Dysfunction, Inflammation, and Oxidative Stress in Streptozotocin Diabetic Rat Model.
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Protein A-induced apoptosis of cancer cells is effected by soluble immune mediators.
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Protein kinase C-eta regulates resistance to UV- and gamma-irradiation-induced apoptosis in glioblastoma cells by preventing caspase-9 activation.
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Proteolysis of the mismatch repair protein MLH1 by caspase-3 promotes DNA damage-induced apoptosis.
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Proteomic and transcriptomic study on the action of a cytotoxic saponin (Polyphyllin D): induction of endoplasmic reticulum stress and mitochondria-mediated apoptotic pathways.
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Proteomic characterization of EL4 lymphoma-derived tumors upon chemotherapy treatment reveals potential roles for lysosomes and caspase-6 during tumor cell death in vivo.
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Proteomics analyses of human optic nerve head astrocytes following biomechanical strain.
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Protocadherin 17 acts as a tumor suppressor inducing tumor cell apoptosis and autophagy, and is frequently methylated in gastric and colorectal cancers.
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Protocatechuic acid inhibits testicular and epididymal toxicity associated with methotrexate in rats.
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Pt(II) complexes of a combretastatin A-4 analogous chalcone: effects of conjugation on cytotoxicity, tumor specificity, and long-term tumor growth suppression.
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PTEN modulates vascular endothelial growth factor-mediated signaling and angiogenic effects.
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Pterostilbene inhibits hepatocellular carcinoma through p53/SOD2/ROS-mediated mitochondrial apoptosis.
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Pterostilbene Inhibits the Growth of Human Esophageal Cancer Cells by Regulating Endoplasmic Reticulum Stress.
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Pulmonary pathobiology induced by zinc oxide nanoparticles in mice: A 24-hour and 28-day follow-up study.
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Pure anti-tumor effect of zoledronic acid in naïve bone-only metastatic and locally advanced breast cancer: proof from the "biological window therapy".
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Purification, characterization and anti-tumor activity of a pectic-type polysaccharide isolated from Ficus pandurata H.
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Purified compounds from marine organism sea pen induce apoptosis in human breast cancer cell MDA-MB-231 and cervical cancer cell Hela.
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Purified human plasma glycosaminoglycans reduced NF-kappaB activation, pro-inflammatory cytokine production and apoptosis in LPS-treated chondrocytes.
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Purple corn color suppresses Ras protein level and inhibits 7,12-dimethylbenz[a]anthracene-induced mammary carcinogenesis in the rat.
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Putative tumor suppressor cytoglobin promotes aryl hydrocarbon receptor ligand-mediated triple negative breast cancer cell death.
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Pyrroloquinoline Quinone Induces Cancer Cell Apoptosis via Mitochondrial-Dependent Pathway and Down-Regulating Cellular Bcl-2 Protein Expression.
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Qizhen capsule inhibits colorectal cancer by inducing NAG-1/GDF15 expression that mediated via MAPK/ERK activation.
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Quantitative Prostate MRI Analysis Following Fluvastatin Therapy for Localized Prostate Cancer - A Pilot Study.
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Quantitatively determined survivin expression levels are of prognostic value in human gliomas.
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Quercetin enhances apoptotic effect of tumor necrosis factor-related apoptosis-inducing ligand (TRAIL) in ovarian cancer cells through reactive oxygen species (ROS) mediated CCAAT enhancer-binding protein homologous protein (CHOP)-death receptor 5 pathway.
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Quercetin Mediated Reduction of Angiogenic Markers and Chaperones in DLA-Induced Solid Tumours.
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Quercus Suber L. Cork Extracts Induce Apoptosis in Human Myeloid Leukaemia HL-60 Cells.
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Quxie Capsule Inhibits Colon Tumor Growth Partially Through Foxo1-Mediated Apoptosis and Immune Modulation.
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Rabaptin-5 is a novel fusion partner to platelet-derived growth factor beta receptor in chronic myelomonocytic leukemia.
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Radiation-Induced RhoGDI? Cleavage Leads to Perturbation of Cell Polarity: A Possible Link to Cancer Spreading.
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Radiation-synthesis of chitosan/poly (acrylic acid) nanogel for improving the antitumor potential of rutin in hepatocellular carcinoma.
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Radiofrequency at 2.45 GHz increases toxicity, pro-inflammatory and pre-apoptotic activity caused by black carbon in the RAW 264.7 macrophage cell line.
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Radiopharmacological evaluation of a caspase-3 responsive probe with optimized pharmacokinetics for PET imaging of tumor apoptosis.
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Radiosensitizer sanazole (AK-2123) enhances gamma-radiation-induced apoptosis in murine fibrosarcoma.
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Radix Tetrastigma Extracts Enhance the Chemosensitivity in Triple-Negative Breast Cancer Via Inhibiting PI3K/Akt/mTOR-Mediated Autophagy.
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Radix Tetrastigma Inhibits the Non-Small Cell Lung Cancer via Bax/Bcl-2/Caspase-9/Caspase-3 Pathway.
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Raised expression of the antiapoptotic protein ped/pea-15 increases susceptibility to chemically induced skin tumor development.
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RANK ligand inhibition plus docetaxel improves survival and reduces tumor burden in a murine model of prostate cancer bone metastasis.
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Rapid Imaging of Tumor Cell Death in vivo using the C2A domain of Synaptotagmin-I.
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Rapid tumor inhibition via magnetic hyperthermia regulated by caspase 3 with time-dependent clearance of iron oxide nanoparticles.
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RasGRP3 in peripheral blood mononuclear cells is associated with disease activity and implicated in the development of systemic lupus erythematosus.
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Rational design of caspase-responsive smart molecular probe for positron emission tomography imaging of drug-induced apoptosis.
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RbAp48 is a critical mediator controlling the transforming activity of human papillomavirus type 16 in cervical cancer.
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Reactive nitrogen intermediates and monokines induce caspase-3 mediated macrophage apoptosis by anaerobically stressed Salmonella typhi.
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Reactive oxygen species-mediated regulation of eNOS and iNOS expression in multicellular prostate tumor spheroids.
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Real Time Detection of In Vitro Tumor Cell Apoptosis Induced by CD8+ T Cells to Study Immune Suppressive Functions of Tumor-infiltrating Myeloid Cells.
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Receptor interacting protein kinases-dependent necroptosis as a new, potent mechanism for elimination of the endothelial cells during luteolysis in cow.
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Reciprocal complementation of the tumoricidal effects of radiation and natural killer cells.
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Recombinant Antisense C-myc Adenovirus Increase in vitro Sensitivity of Osteosarcoma MG-63 Cells to Cisplatin.
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Recombinant mistletoe lectin induces p53-independent apoptosis in tumour cells and cooperates with ionising radiation.
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Reconstitution of caspase-3 confers low glucose-enhanced tumor necrosis factor-related apoptosis-inducing ligand cytotoxicity and Akt cleavage.
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Reconstitution of caspase-3 sensitizes MCF-7 breast cancer cells to radiation therapy.
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Reconstitution of human MCF-7 breast cancer cells with caspase-3 does not sensitize them to action of CDK inhibitors.
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RedOx status, proteasome and APEH: insights into anticancer mechanisms of t10,c12-conjugated linoleic acid isomer on A375 melanoma cells.
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Reduced expression of caspase-8 and cleaved caspase-3 in pancreatic ductal adenocarcinoma cells.
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Reduced liver injury and cytokine release after transplantation of preconditioned intestines.
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Reduced tumor growth in vivo and increased c-Abl activity in PC3 prostate cancer cells overexpressing the Shb adapter protein.
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Reduction of graphene oxide by resveratrol: a novel and simple biological method for the synthesis of an effective anticancer nanotherapeutic molecule.
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Reduction of TIP30 correlates with poor prognosis of gastric cancer patients and its restoration drastically inhibits tumor growth and metastasis.
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Regression of glioma tumor growth in F98 and U87 rat glioma models by the Nitrone OKN-007.
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Regulation of apoptosis by p53-inducible transmembrane protein containing sushi domain.
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Regulation of cell apoptosis and proliferation in pancreatic cancer through PI3K/Akt pathway via Polo-like kinase 1.
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Regulation of isocyanate-induced apoptosis, oxidative stress, and inflammation in cultured human neutrophils : Isocyanate-induced neutrophils apoptosis.
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Regulation of Sirtuin 3-Mediated Deacetylation of Cyclophilin D Attenuated Cognitive Dysfunction Induced by Sepsis-Associated Encephalopathy in Mice.
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Relationship between intracellular pH, metabolic co-factors and caspase-3 activation in cancer cells during apoptosis.
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Relationship between the expression of caspase-3 and the clinical outcome of patients with non-small cell lung cancer.
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Relevance of a new rat model of osteoblastic metastases from prostate carcinoma for preclinical studies using zoledronic acid.
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Remarkable apoptotic pathway of Hemiscorpius lepturus scorpion venom on CT26 cell line.
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Renoprotective effect of Hypericum perforatum against diabetic nephropathy in rats: Insights in the underlying mechanisms.
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Renoprotective effect of local sildenafil administration in renal ischaemia-reperfusion injury: A randomised controlled canine study.
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Renoprotective effects of angiotensin receptor blocker and stem cells in acute kidney injury: Involvement of inflammatory and apoptotic markers.
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Reovirus-associated reduction of microRNA-let-7d is related to the increased apoptotic death of cancer cells in clinical samples.
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Repression of caspase-3 and RNA-binding protein HuR cleavage by cyclooxygenase-2 promotes drug resistance in oral squamous cell carcinoma.
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Repression of tumor necrosis factor-related apoptosis-inducing ligand (TRAIL) but not its receptors during oral cancer progression.
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Repurposing the serotonin agonist Tegaserod as an anticancer agent in melanoma: molecular mechanisms and clinical implications.
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Research on protective mechanism of ibuprofen in myocardial ischemia-reperfusion injury in rats through the PI3K/Akt/mTOR signaling pathway.
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Resistance exercise improves short-term memory through inactivation of NF-?B pathway in mice with Parkinson disease.
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RESISTANCE TO FAS-MEDIATED APOPTOSIS IN MALIGNANT TUMOURS IS RESCUED BY KN-93 AND CISPLATIN VIA DOWNREGULATION OF c-FLIP EXPRESSION AND PHOSPHORYLATION.
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Resolvin D1 protects against cadmium chloride-induced memory loss and hippocampal damage in rats: A comparison with docosahexaenoic acid.
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Resveratrol Induces Premature Senescence in Lung Cancer Cells via ROS-Mediated DNA Damage.
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Resveratrol: Isolation, and Its Nanostructured, Inhibits Cell Proliferation, Induces Cell Apoptosis in Certain Human Cell Lines Carcinoma and Exerts Protective Effect Against Paraquat-Induced Hepatotoxicity.
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Retinoic acid amide inhibits JAK/STAT pathway in lung cancer which leads to apoptosis.
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Revealing the therapeutic targets and molecular mechanisms of emodin-treated coronavirus disease 2019 via a systematic study of network pharmacology.
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Reversal of multidrug resistance by magnetic Fe3O4 nanoparticle copolymerizating daunorubicin and 5-bromotetrandrine in xenograft nude-mice.
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Reversal of Multidrug Resistance in Xenograft Nude-mice by Magnetic Fe(3)O(4) Nanoparticles Combined with Daunorubicin and 5-Bromotetrandrine.
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Reversible glutathiolation of caspase-3 by glutaredoxin as a novel redox signaling mechanism in tumor necrosis factor-alpha-induced cell death.
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RF hyperthermia by encapsulated Fe3O4 nanoparticles induces cancer cell death via time-dependent caspase-3 activation.
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Ricinus communis agglutinin I leads to rapid down-regulation of VEGFR-2 and endothelial cell apoptosis in tumor blood vessels.
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Role of ATP in trauma-associated cytokine release and apoptosis by P2X7 ion channel stimulation.
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Role of ATP-Sensitive Potassium Channel (KATP) and eNOS in Mediating the Protective Effect of Nicorandil in Cyclophosphamide-Induced Cardiotoxicity.
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Role of autophagy in temozolomide-induced cytotoxicity for malignant glioma cells.
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Role of caspase-3 and nitric oxide synthase-2 in gastric mucosal injury induced by indomethacin: effect of sucralfate.
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Role of Caspases, Bax and Bcl-2 in Chrysin-Induced Apoptosis in the A549 Human Lung Adenocarcinoma Epithelial Cells.
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Role of cellular zinc in programmed cell death: temporal relationship between zinc depletion, activation of caspases, and cleavage of Sp family transcription factors.
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Role of ellagic acid in regulation of apoptosis by modulating novel and atypical PKC in lymphoma bearing mice.
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Role of high-mobility group B1 in myocardial injury induced by coronary microembolization in rats.
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Role of leucine-rich pentatricopeptide repeat motif-containing protein (LRPPRC) for anti-apoptosis and tumourigenesis in cancers.
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Role of LPA and the Hippo pathway on apoptosis in salivary gland epithelial cells.
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Role of mitogen-activated protein kinases in S-nitrosoglutathione-induced macrophage apoptosis.
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Role of nitrergic and endothelin pathways modulations in cisplatin-induced nephrotoxicity in male rats.
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Role of nuclear factor-kappaB in volatile anaesthetic preconditioning with sevoflurane during myocardial ischaemia/reperfusion.
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Role of poly(ADP-ribose) polymerase (PARP) cleavage in apoptosis. Caspase 3-resistant PARP mutant increases rates of apoptosis in transfected cells.
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Role of thymoquinone and ebselen in the prevention of sodium arsenite-induced nephrotoxicity in female rats.
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Roles of oxidative stress, apoptosis, and inflammation in metal-induced dysfunction of beta pancreatic cells isolated from CD1 mice.
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Rosiglitazone enhances the radiosensitivity of p53-mutant HT-29 human colorectal cancer cells.
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RPB5-mediating protein promotes the progression of non-small cell lung cancer by regulating the proliferation and invasion.
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Ru(II)-Thymine Complex Causes Cell Growth Inhibition and Induction of Caspase-Mediated Apoptosis in Human Promyelocytic Leukemia HL-60 Cells.
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RU486-inducible retrovirus-mediated caspase-3 overexpression is cytotoxic to bcl-xL-expressing myeloma cells in vitro and in vivo.
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Rumex japonicus Houtt. alleviates dextran sulfate sodium-induced colitis by protecting tight junctions in mice.
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Ruthenium(II) p-cymene complex bearing 2,2'-dipyridylamine targets caspase 3 deficient MCF-7 breast cancer cells without disruption of antitumor immune response.
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Ruthenium-loaded mesoporous silica as tumor microenvironment-response nano-fenton reactors for precise cancer therapy.
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Rutin, a quercetin glycoside, alleviates acute endotoxemic kidney injury in C57BL/6 mice via suppression of inflammation and up-regulation of antioxidants and SIRT1.
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S-allylcysteine, a water-soluble garlic derivative, suppresses the growth of a human androgen-independent prostate cancer xenograft, CWR22R, under in vivo conditions.
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S-allylmercaptocysteine promotes MAPK inhibitor-induced apoptosis by activating the TGF-? signaling pathway in cancer cells.
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S100A4 promotes pancreatic cancer progression through a dual signaling pathway mediated by Src and focal adhesion kinase.
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Safe and targeted anticancer efficacy of a novel class of antioxidant-conjugated difluorodiarylidenyl piperidones: differential cytotoxicity in healthy and cancer cells.
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Safflower polysaccharide induces NSCLC cell apoptosis by inhibition of the Akt pathway.
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Safflower polysaccharide inhibits the development of tongue squamous cell carcinoma.
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Safflower seed extract synergizes the therapeutic effect of cisplatin and reduces cisplatin-induced nephrotoxicity in human colorectal carcinoma RKO cells and RKO-transplanted mice.
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Safranal, a constituent of saffron, exerts gastro-protective effects against indomethacin-induced gastric ulcer.
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Safranal, an active ingredient of saffron, attenuates cognitive deficits in amyloid ?-induced rat model of Alzheimer's disease: underlying mechanisms.
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Saikosaponin D inhibits proliferation of human osteosarcoma cells via the p53 signaling pathway.
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Saikosaponin-A induces apoptosis of cervical cancer through mitochondria- and endoplasmic reticulum stress-dependent pathway in vitro and in vivo: involvement of PI3K/AKT signaling pathway.
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Salmonella typhimurium with ?-radiation induced H2AX phosphorylation and apoptosis in melanoma.
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Salvianolic acid B attenuates hepatocyte apoptosis by regulating mediators in death receptor and mitochondrial pathways.
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Salvianolic acid B attenuates lipopolysaccharide-induced acute lung injury in rats through inhibition of apoptosis, oxidative stress and inflammation.
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Sann-Joong-Kuey-Jian-Tang decreases the protein expression of Mcl?1 and TCTP and increases that of TNF-? and Bax in BxPC?3 pancreatic carcinoma cells.
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Sann-Joong-Kuey-Jian-Tang inhibits hepatocellular carcinoma Hep-G2 cell proliferation by increasing TNF-?, Caspase-8, Caspase- 3 and Bax but by decreasing TCTP and Mcl-1 expression in vitro.
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Sann-Joong-Kuey-Jian-Tang up-regulates the protein expression of Fas and TNF-? in colo 205 cells in vivo and in vitro.
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Saururus chinensis Baill inhibits proliferation and invasion of human renal cell carcinoma cells through inhibition of inhibitor of apoptosis protein.
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Saxagliptin defers thioacetamide-induced hepatocarcinogenesis in rats: A novel suppressive impact on Wnt/Hedgehog/Notch1 signaling.
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SB203580 Modulates p38 MAPK Signaling and Dengue Virus-Induced Liver Injury by Reducing MAPKAPK2, HSP27, and ATF2 Phosphorylation.
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SB365 inhibits angiogenesis and induces apoptosis of hepatocellular carcinoma through modulation of PI3K/Akt/mTOR signaling pathway.
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Sca-1 enriches for a cancer stem cell-like subpopulation in mouse gastric cancer.
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Sca-1 identifies the tumor-initiating cells in mammary tumors of BALB-neuT transgenic mice.
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Scabraside D Derived from Sea Cucumber Induces Apoptosis and Inhibits Metastasis via iNOS and STAT-3 Expression in Human Cholangiocarcinoma Xenografts.
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Scientific validation of cardioprotective attribute by standardized extract of Bombyx mori against doxorubicin-induced cardiotoxicity in murine model.
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Screening of a novel octamer peptide, CNSCWSKD, that induces caspase-dependent cell death.
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Screening of caspase-3 inhibitors from natural molecule database using e-pharmacophore and docking studies.
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Scutellaria barbata D. Don extract synergizes the antitumor effects of low dose 5-fluorouracil through induction of apoptosis and metabolism.
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Se-methylselenocysteine activates caspase-3 in mouse mammary epithelial tumor cells in vitro.
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Searching in mother nature for anti-cancer activity: anti-proliferative and pro-apoptotic effect elicited by green barley on leukemia/lymphoma cells.
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Secondary metabolic profiles and anticancer actions from fruit extracts of immature pomegranates.
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Secretion of IL-16 through TNFR1 and calpain-caspase signaling contributes to MRSA pneumonia.
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Seladin-1 and testicular germ cell tumours: new insights into cisplatin responsiveness.
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Selected Clinical Features Fail to Predict Inflammatory Gene Expressions for TNF-?, TNFR1, NSMAF, Casp3 and IL-8 in Tendons of Patients with Rotator Cuff Tendinopathy.
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Selected gene profiles of stressed NSC-34 cells and rat spinal cord following peripheral nerve reconstruction and minocycline treatment.
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Selective ablation of ligament of Marshall inhibits ventricular arrhythmias during acute myocardial infarction: Possible mechanisms.
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Selective cytotoxic activity and protective effects of sodium ascorbate against hepatocellular carcinoma through its effect on oxidative stress and apoptosis in vivo and in vitro.
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Selective ETA receptor blockade protects against cisplatin-induced acute renal failure in male rats.
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Selective induction of apoptosis in various cancer cells irrespective of drug sensitivity through a copper chelate, copper N-(2 hydroxy acetophenone) glycinate: crucial involvement of glutathione.
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Selective Inhibitors of CYP2J2 Related to Terfenadine Exhibit Activity Strongly against Human Cancers in vitro and in vivo.
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Selective involvement of caspase-3 in ceramide induced apoptosis in AK-5 tumor cells.
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Selective proapoptotic activity of polyphenols from red wine on teratocarcinoma cell, a model of cancer stem-like cell.
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Selenium-Containing Polysaccharide-Protein Complex in Se-Enriched Ulva fasciata Induces Mitochondria-Mediated Apoptosis in A549 Human Lung Cancer Cells.
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Selenoprotein Genes Exhibit Differential Expression Patterns Between Hepatoma HepG2 and Normal Hepatocytes LO2 Cell Lines.
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Self-assembled nucleo-tripeptide hydrogels provide local and sustained doxorubicin release.
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Self-nanoemulsifying drug-delivery systems for potentiated anti-inflammatory activity of diacerein.
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Self-Triggered Apoptosis Enzyme Prodrug Therapy (STAEPT): Enhancing Targeted Therapies via Recurrent Bystander Killing Effect by Exploiting Caspase-Cleavable Linker.
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SEMA4D Knockdown Attenuates ?-Catenin-Dependent Tumor Progression in Colorectal Cancer.
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Sensitive and selective plasmon ruler nanosensors for monitoring the apoptotic drug response in leukemia.
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Sensitivity to differential NRF1 gene signatures contributes to breast cancer disparities.
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Sensitization by glycerol for CDDP-therapy against human cultured cancer cells and tumors bearing mutated p53 gene.
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Sensitization of colorectal cancer to irinotecan therapy by PARP inhibitor rucaparib.
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Sevoflurane anesthesia alters cognitive function by activating inflammation and cell death in rats.
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Sevoflurane prevents liver inflammatory response induced by lung ischemia-reperfusion.
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Sevoflurane Protects against Intestinal Ischemia-Reperfusion Injury by Activating Peroxisome Proliferator-Activated Receptor Gamma/Nuclear Factor-?B Pathway in Rats.
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SH-5, an AKT inhibitor potentiates apoptosis and inhibits invasion through the suppression of anti-apoptotic, proliferative and metastatic gene products regulated by IkappaBalpha kinase activation.
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Sh3bp2 Gain-Of-Function Mutation Ameliorates Lupus Phenotypes in B6.MRL-Faslpr Mice.
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Shexiang Tongxin dropping pill protects against sodium laurate-induced coronary microcirculatory dysfunction in rats.
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Shikonin induces tumor apoptosis in glioma cells via endoplasmic reticulum stress, and Bax/Bak mediated mitochondrial outer membrane permeability.
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Shiquan Yuzhen Decoction inhibits angiogenesis and tumor apoptosis caused by non-small cell lung cancer and promotes immune response.
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Shogaols at proapoptotic concentrations induce G(2)/M arrest and aberrant mitotic cell death associated with tubulin aggregation.
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Short interfering RNA against the PDCD5 attenuates cell apoptosis and caspase-3 activity induced by Bax overexpression.
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Showing NAFLD, as a key connector disease between Alzheimer's disease and diabetes via analysis of systems biology.
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Shrimp shells extracted chitin in silver nanoparticle synthesis: Expanding its prophecy towards anticancer activity in human hepatocellular carcinoma HepG2 cells.
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Shuttling SLC2A4RG is regulated by 14-3-3? to modulate cell survival via caspase-3 and caspase-6 in human glioma.
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Shuxuetong injection protects cerebral microvascular endothelial cells against oxygen-glucose deprivation reperfusion.
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Sialic acid surface decoration enhances cellular uptake and apoptosis-inducing activity of selenium nanoparticles.
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Sigma-2 receptor ligand as a novel method for delivering a SMAC mimetic drug for treating ovarian cancer.
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Sildenafil increases chemotherapeutic efficacy of doxorubicin in prostate cancer and ameliorates cardiac dysfunction.
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Sildenafil potentiates the antitumor activity of cisplatin by induction of apoptosis and inhibition of proliferation and angiogenesis.
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Sildenafil protects against nitric oxide deficiency-related nephrotoxicity in cyclosporine A treated rats.
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Silencing Bcl-2 in models of mantle cell lymphoma is associated with decreases in cyclin D1, nuclear factor-kappaB, p53, bax, and p27 levels.
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Silencing long non-coding RNA, differentiation antagonizing non-protein coding RNA promotes apoptosis and inhibits tumor growth in colon cancer.
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Silencing of Fas, but not caspase-8, in lung epithelial cells ameliorates pulmonary apoptosis, inflammation, and neutrophil influx after hemorrhagic shock and sepsis.
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Silencing of HSulf-2 expression in MCF10DICS.com cells attenuate ductal carcinoma in situ progression to invasive ductal carcinoma in vivo.
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Silencing the gene encoding C/EBP homologous protein lessens acute brain injury following ischemia/reperfusion.
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Silibinin Inhibits Tumor Growth through Downregulation of Extracellular Signal-Regulated Kinase and Akt in Vitro and in Vivo in Human Ovarian Cancer Cells.
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Silibinin protects against photocarcinogenesis via modulation of cell cycle regulators, mitogen-activated protein kinases, and Akt signaling.
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Silver nanoparticles provoke apoptosis of Dalton's ascites lymphoma in vivo by mitochondria dependent and independent pathways.
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Simulating sleep apnea by exposure to intermittent hypoxia induces inflammation in the lung and liver.
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Simultaneous measurement of perillyl alcohol and its metabolite perillic acid in plasma and lung after inhalational administration in Wistar rats.
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Simvastatin Alleviates Intestinal Ischemia/Reperfusion Injury by Modulating Omi/HtrA2 Signaling Pathways.
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Simvastatin Protects Hepatocytes From Apoptosis by Suppressing the TNF-?/Caspase-3 Signaling Pathway in Mice With Burn Injury.
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Simvastatin treatment ameliorates injury of rat testes induced by cadmium toxicity.
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Single-cell microinjection assay indicates that 7-hydroxycoumarin induces rapid activation of caspase-3 in A549 cancer cells.
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Single-molecule sensing of caspase activation in live cells via plasmon coupling nanotechnology.
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Single-Photon Emission Computed Tomographic Imaging of the Early Time Course of Therapy-Induced Cell Death Using Technetium 99m Tricarbonyl His-Annexin A5 in a Colorectal Cancer Xenograft Model.
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Single-photon emission computed tomographic imaging of the early time course of therapy-induced cell death using technetium 99m tricarbonyl His-annexin A5 in a colorectal cancer xenograft model.
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Sinoporphyrin Sodium-Mediated Sonodynamic Therapy Inhibits RIP3 Expression and Induces Apoptosis in the H446 Small Cell Lung Cancer Cell Line.
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Sirt-1 is required for the inhibition of apoptosis and inflammatory responses in human tenocytes.
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SIRT1 exerts neuroprotective effects by attenuating cerebral ischemia/reperfusion-induced injury via targeting p53/microRNA-22.
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Sitagliptin ameliorates thioacetamide-induced acute liver injury via modulating TLR4/NF-KB signaling pathway in mice.
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Skeletal muscle apoptosis is not increased in gastric cancer patients with mild-moderate weight loss.
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SKLB-M8 induces apoptosis through the AKT/mTOR signaling pathway in melanoma models and inhibits angiogenesis with decrease of ERK1/2 phosphorylation.
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SL-01, an oral gemcitabine derivative, inhibited human cancer growth more potently than gemcitabine.
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Slug promotes survival during metastasis through suppression of Puma-mediated apoptosis.
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SM-1, a novel PAC-1 derivative, activates procaspase-3 and causes cancer cell apoptosis.
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Small molecule XIAP inhibitors enhance TRAIL-induced apoptosis and antitumor activity in preclinical models of pancreatic carcinoma.
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Small-molecule activation of procaspase-3 to caspase-3 as a personalized anticancer strategy.
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SNS-314, a pan-Aurora kinase inhibitor, shows potent anti-tumor activity and dosing flexibility in vivo.
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Sodium Danshensu promotes the healing of stage 2 pressure injury wounds in ischemia/reperfusion injury rat models: possible regulation of apoptosis and inflammatory response.
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Sodium hydrogen sulfide upregulates cystathionine ?-synthase and protects striatum against 3-nitropropionic acid-induced neurotoxicity in rats.
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Sodium Tanshinone IIA Sulfonate Attenuates Tumor Oxidative Stress and Promotes Apoptosis in an Intermittent Hypoxia Mouse Model.
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Solanine induces mitochondria-mediated apoptosis in human pancreatic cancer cells.
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Soybean Glycinin- and ?-Conglycinin-Induced Intestinal Damage in Piglets via the p38/JNK/NF-?B Signaling Pathway.
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SPARC functions as an anti-stress factor by inactivating p53 through Akt-mediated MDM2 phosphorylation to promote melanoma cell survival.
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Spatiotemporal expression profile of proteases and immunological, angiogenic, hormonal and apoptotic mediators in rat placenta before and during intrauterine trophoblast migration.
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Specific cleavage of Mcl-1 by caspase-3 in tumor necrosis factor-related apoptosis-inducing ligand (TRAIL)-induced apoptosis in Jurkat leukemia T cells.
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Sphere formation reverses the metastatic and cancer stem cell phenotype of the murine mammary tumour 4T1, independently of the putative cancer stem cell marker Sca-1.
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Sphingosine 1-phosphate antagonizes apoptosis of human leukemia cells by inhibiting release of cytochrome c and Smac/DIABLO from mitochondria.
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Sphingosine kinase 2 inhibitor ABC294640 displays anti-epithelial ovarian cancer activities in vitro and in vivo.
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Spillover of cytokines and reactive oxygen species in ventilator-induced lung injury associated with inflammation and apoptosis in distal organs.
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Spirooxindole-pyrrolidine heterocyclic hybrids promotes apoptosis through activation of caspase-3.
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Spirulina platensis prevents hyperglycemia in rats by modulating gluconeogenesis and apoptosis via modification of oxidative stress and MAPK-pathways.
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Spontaneous apoptosis of Reed-Sternberg and Hodgkin cells; clinical and pathological implications in patients with Hodgkin's disease.
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ST-11: A New Brain-Penetrant Microtubule-Destabilizing Agent with Therapeutic Potential for Glioblastoma Multiforme.
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Stable silencing of ROR1 regulates cell cycle, apoptosis, and autophagy in a lung adenocarcinoma cell line.
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Stable transfection of extrinsic Smac gene enhances apoptosis-inducing effects of chemotherapeutic drugs on gastric cancer cells.
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Stat3-siRNA induces Fas-mediated apoptosis in vitro and in vivo in breast cancer.
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Staurosporine-induced death of MCF-7 human breast cancer cells: a distinction between caspase-3-dependent steps of apoptosis and the critical lethal lesions.
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Stem cell antigen-1 deficiency enhances the chemopreventive effect of peroxisome proliferator-activated receptor? activation.
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Stem cell antigen-1 enhances tumorigenicity by disruption of growth differentiation factor-10 (GDF10)-dependent TGF-beta signaling.
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Stereoisomers of Astaxanthin Inhibit Human Colon Cancer Cell Growth by Inducing G2/M Cell Cycle Arrest and Apoptosis.
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Steroids from Helleborus caucasicus reduce cancer cell viability inducing apoptosis and GRP78 down-regulation.
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Stimulation of ACE2/ANG(1-7)/Mas Axis by Diminazene Ameliorates Alzheimer's Disease in the D-Galactose-Ovariectomized Rat Model: Role of PI3K/Akt Pathway.
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Stimulation of microglial metabotropic glutamate receptor mGlu2 triggers tumor necrosis factor alpha-induced neurotoxicity in concert with microglial-derived Fas ligand.
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STING Ligand c-di-GMP Improves Cancer Vaccination against Metastatic Breast Cancer.
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Stomach cancer highly expresses both initiator and effector caspases; an immunohistochemical study.
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Strawberry Leaf Extract Treatment Alleviates Cognitive Impairment by Activating Nrf2/HO-1 Signaling in Rats With Streptozotocin-Induced Diabetes.
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Stroma-dependent apoptosis in clonal hematopoietic precursors correlates with expression of PYCARD.
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Stromal Features of the Primary Tumor Are Not Prognostic in Genetically Engineered Mice of Pancreatic Cancer.
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Structural Analysis of the cl-Par-4 Tumor Suppressor as a Function of Ionic Environment.
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Structural Change in Microbiota by a Probiotic Cocktail Enhances the Gut Barrier and Reduces Cancer via TLR2 Signaling in a Rat Model of Colon Cancer.
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Structurally related antitumor effects of flavanones in vitro and in vivo: involvement of caspase 3 activation, p21 gene expression, and reactive oxygen species production.
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Structure-based virtual screening, biological evaluation and biophysical study of novel Mcl-1 inhibitors.
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Stryphnodendron adstringens ("Barbatimão") Leaf Fraction: Chemical Characterization, Antioxidant Activity, and Cytotoxicity Towards Human Breast Cancer Cell Lines.
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Study of RNA Interference Targeting NET-1 Combination with Sorafenib for Hepatocellular Carcinoma Therapy In Vitro and In Vivo.
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Study on antitumor, antioxidant and immunoregulatory activities of the purified polyphenols from pinecone of Pinus koraiensis on tumor-bearing S180 mice in vivo.
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Study on the anti-hepatocarcinoma effect and molecular mechanism of Prunella vulgaris total flavonoids.
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Study on the mechanism of photodynamic therapy mediated by 5-aminoketovalerate in human ovarian cancer cell line.
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Study on the Molecular Mechanisms Against Human Breast Cancer from Insight of Elemental Distribution in Tissue Based on Laser-Induced Breakdown Spectroscopy (LIBS).
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Subnormothermic machine perfusion protects steatotic livers against preservation injury: a potential for donor pool increase?
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Substitution at the indole 3 position yields highly potent indolecombretastatins against human tumor cells.
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Suicide HSVtk gene delivery by neurotensin-polyplex nanoparticles via the bloodstream and GCV Treatment specifically inhibit the growth of human MDA-MB-231 triple negative breast cancer tumors xenografted in athymic mice.
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Sulindac enhances adenoviral vector expressing mda-7/IL-24-mediated apoptosis in human lung cancer.
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Sunitinib malate inhibits intestinal tumor development in male ApcMin/+ mice by down-regulating inflammation-related factors with suppressing ?-cateinin/c-Myc pathway and re-balancing Bcl-6 and Caspase-3.
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Superficial synthesis of photoactive copper sulfide quantum dots loaded nano-graphene oxide sheets combined with near infrared (NIR) laser for enhanced photothermal therapy on breast cancer in nursing care management.
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Superior in vivo inhibitory efficacy of methylseleninic acid against human prostate cancer over selenomethionine or selenite.
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Suppression of apoptosis by glucocorticoids in glomerular endothelial cells: effects on proapoptotic pathways.
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Suppression of autophagy by CDCP1 signaling is essential for anchorage-independent survival of lung cancer cells.
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Suppression of cell transformation and induction of apoptosis by caffeic acid phenethyl ester.
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Suppression of colorectal tumorigenesis by recombinant Bacteroides fragilis enterotoxin-2 in vivo.
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Suppression of Metastatic Melanoma Growth in Lung by Modulated Electro-Hyperthermia Monitored by a Minimally Invasive Heat Stress Testing Approach in Mice.
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Suppression of NF-?B and NF-?B-Regulated Gene Expression by Apigenin through I?B? and IKK Pathway in TRAMP Mice.
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Suppression of NF-kappa B survival signaling by nitrosylcobalamin sensitizes neoplasms to the anti-tumor effects of Apo2L/TRAIL.
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Suppression of NF-kappabeta signaling pathway by tocotrienol can prevent diabetes associated cognitive deficits.
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Suppression of proliferation and migration in highly-metastatic lung cancer cells as well as tumor growth by a new synthesized compound TBrC and its molecular mechanisms of action.
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Suppression of the p66shc adapter protein by protocatechuic acid prevents the development of lung injury induced by intestinal ischemia reperfusion in mice.
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Suppression of tumor proliferation and angiogenesis of hepatocellular carcinoma by HS-104, a novel phosphoinositide 3-kinase inhibitor.
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Suppression of vascular endothelial growth factor-mediated endothelial cell protection by survivin targeting.
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Suppressor of cytokine signaling 1 inhibits apoptosis of islet grafts through caspase 3 and apoptosis-inducing factor pathways in rats.
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Suramin decreases injury and improves regeneration of ethanol-induced steatotic partial liver grafts.
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Surface Functionalization of Green-synthesized Reduced Graphene Oxide with PPIX Enhances Photosensitization of Cancer Cells.
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Surgical removal of the parametrial fat pads stimulates apoptosis and inhibits UVB-induced carcinogenesis in mice fed a high-fat diet.
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Survey of the effect of doxorubicin and flavonoid extract of white Morus alba leaf on apoptosis induction in a-172 GBM cell line.
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Survivin and Related Proteins in Canine Mammary Tumors: Immunohistochemical Expression.
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Survivin splice variants are not essential for mitotic progression or inhibition of apoptosis induced by doxorubicin and radiation.
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Susceptibility of Asialoglycoprotein Receptor-Deficient Mice to Lps/Galactosamine Liver Injury and Protection by Betaine Administration.
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Susceptibility to Fas and tumor necrosis factor-alpha receptor mediated apoptosis of anti-CD3/anti-CD28-activated umbilical cord blood T cells.
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Sustained inhibition of tumor growth and prolonged survival following sequential administration of doxorubicin and zoledronic acid in a breast cancer model.
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Sustained tumour eradication after induced caspase-3 activation and synchronous tumour apoptosis requires an intact host immune response.
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Swainsonine Activates Mitochondria-mediated Apoptotic Pathway in Human Lung Cancer A549 Cells and Retards the Growth of Lung Cancer Xenografts.
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Swainsonine promotes apoptosis in human oesophageal squamous cell carcinoma cells in vitro and in vivo through activation of mitochondrial pathway.
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Switching off HER-2/neu in a tetracycline-controlled mouse tumor model leads to apoptosis and tumor-size-dependent remission.
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Sym004, a novel EGFR antibody mixture, can overcome acquired resistance to cetuximab.
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Sympathectomy reduces tumor weight and affects expression of tumor-related genes in melanoma tissue in the mouse.
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Syndecan-1 knockdown in endometrial epithelial cells alters their apoptotic protein profile and enhances the inducibility of apoptosis.
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Synergic effect of 3'-azido-3'-deoxythymidine and arsenic trioxide in suppressing hepatoma cells.
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Synergistic anti-colon cancer effect of glycyrol and butyrate is associated with the enhanced activation of caspase-3 and structural features of glycyrol.
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Synergistic anti-tumour effects of Clostridium butyricum in combination with apatinib in CT26 colorectal tumour-bearing mice.
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Synergistic anticancer effects of combined ?-tocotrienol and oridonin treatment is associated with the induction of autophagy.
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Synergistic Anticancer Effects of Formononetin and Temozolomide on Glioma C6 Cells.
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Synergistic anticancer efficacy of MEK inhibition and dual PI3K/mTOR inhibition in castration-resistant prostate cancer.
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Synergistic antiproliferative effect of arsenic trioxide combined with bortezomib in HL60 cell line and primary blasts from patients affected by myeloproliferative disorders.
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Synergistic antiproliferative effects of an mTOR inhibitor (rad001) plus gemcitabine on cholangiocarcinoma by decreasing choline kinase activity.
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Synergistic Effect of Celecoxib on TRAIL-induced Apoptosis in Hepatocellular Carcinoma Cells.
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Synergistic efficacy of ?-radiation together with gallium trichloride and/or doxorubicin against Ehrlich carcinoma in female mice.
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Synergistic induction of apoptosis by combination treatment with mesupron and auranofin in human breast cancer cells.
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Synergistic interactions of chemotherapeutic drugs and tumor necrosis factor-related apoptosis-inducing ligand/Apo-2 ligand on apoptosis and on regression of breast carcinoma in vivo.
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Synergistic neuroprotective effects of hyperbaric oxygen and methylprednisolone following contusive spinal cord injury in rat.
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Synergistic role of Caspase-8 and Caspase-3 expressions: Prognostic and predictive biomarkers in colorectal cancer.
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Synthesis and antiproliferative evaluation of certain indeno[1,2-c]quinoline derivatives. Part 2.
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Synthesis and Antitumor Activity of Doxycycline Polymeric Nanoparticles: Effect on Tumor Apoptosis in Solid Ehrlich Carcinoma.
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Synthesis and antitumor activity of pyrido [2,3-d]pyrimidine and pyrido[2,3-d] [1,2,4]triazolo[4,3-a]pyrimidine derivatives that induce apoptosis through G1 cell-cycle arrest.
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Synthesis and apoptotic activity of new pyrazole derivatives in cancer cell lines.
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Synthesis and biological evaluation of andrographolide analogues as anti-cancer agents.
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Synthesis and structure-activity relationship of N-(piperidin-4-yl)benzamide derivatives as activators of hypoxia-inducible factor 1 pathways.
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Synthesis of 1-acetyl-3-(2-thienyl)-5-aryl-2-pyrazoline derivatives and evaluation of their anticancer activity.
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Synthesis of 26-hydroxy-22-oxocholestanic frameworks from diosgenin and hecogenin and their in vitro antiproliferative and apoptotic activity on human cervical cancer CaSki cells.
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Synthesis of a new ent-cyclozonarone angular analog, and comparison of its cytotoxicity and apoptotic effects with ent-cyclozonarone.
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Synthesis of New N(1)-Substituted-5-aryl-3-(3,4,5-trimethoxyphenyl)-2-pyrazoline Derivatives as Antitumor Agents Targeting the Colchicine Site on Tubulin.
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Synthesis of Novel Xanthone Analogues and Their Growth Inhibitory Activity Against Human Lung Cancer A549 Cells.
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Synthesis of steroidal imidazolidinthiones as potential apoptotic agents: Investigation by theoretical and experimental studies.
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Synthesis of the steroidal glycoside (25R)-3?,16?-diacetoxy-12,22-dioxo-5?-cholestan-26-yl ?-D-glucopyranoside and its anti-cancer properties on cervicouterine HeLa, CaSki, and ViBo cells.
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Synthesis of Tolmetin Hydrazide-Hydrazones and Discovery of a Potent Apoptosis Inducer in Colon Cancer Cells.
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Synthesis, Anticancer Activity, Effect on Cell Cycle Profile, and Apoptosis-Inducing Ability of Novel Hexahydrocyclooctathieno[2,3-d]pyrimidine Derivatives.
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Synthesis, Cancer-Selective Antiproliferative and Apoptotic Effects of Some (±)-Naringenin Cycloaminoethyl Derivatives.
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Synthesis, characterization and antitumor activity of Ln(III) complexes with hydrazone Schiff base derived from 2-acetylpyridine and isonicotinohydrazone.
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Synthesis, characterization and evaluation of resveratrol-loaded functionalized carbon nanotubes as a novel delivery system in radiation enteropathy.
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Synthesis, cytotoxicity, and pro-apoptosis activity of etodolac hydrazide derivatives as anticancer agents.
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Synthesis, structure-activity relationship and biological evaluation of 2,4,5-trisubstituted pyrimidine CDK inhibitors as potential anti-tumour agents.
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Systemic administration of autologous adipose-derived mesenchymal stem cells alleviates hepatic ischemia-reperfusion injury in rats.
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Systemic delivery of axitinib with nanohybrid liposomal nanoparticles inhibits hypoxic tumor growth.
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SYUNZ-16, a newly synthesized alkannin derivative, induces tumor cells apoptosis and suppresses tumor growth through inhibition of PKB/AKT kinase activity and blockade of AKT/FOXO signal pathway.
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Syzygium samarangense leaf extract mitigates indomethacin-induced gastropathy via the NF-?B signaling pathway in rats.
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T-bet transduction enhances anti-tumor efficacy of IFN-producing dendritic cell (IKDC) against hepatocellular carcinoma via apoptosis induction.
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t-Darpp promotes cancer cell survival by up-regulation of Bcl2 through Akt-dependent mechanism.
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Tadpole serum activity (Rana catesbeian a) in caspase-3 as a marker of the role of apoptosis and total cytotoxic T lymphocytes in albino rats' epithelial cells induced by neoplasia.
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TAK1 kinase determines TRAIL sensitivity by modulating reactive oxygen species and cIAP.
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Tambulin Targets Histone Deacetylase 1 Inhibiting Cell Growth and Inducing Apoptosis in Human Lung Squamous Cell Carcinoma.
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Tanshinone IIA inhibits human gastric carcinoma AGS cell growth by decreasing BiP, TCTP, Mcl?1 and Bcl?xL and increasing Bax and CHOP protein expression.
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Tanshinone IIA inhibits human hepatocellular carcinoma J5 cell growth by increasing Bax and caspase 3 and decreasing CD31 expression in vivo.
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Targeted apoptotic effects of thymoquinone and tamoxifen on XIAP mediated Akt regulation in breast cancer.
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Targeted delivery of 20(S)-ginsenoside Rg3-based polypeptide nanoparticles to treat colon cancer.
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Targeted H(+)-Triggered Bubble-Generating Nanosystems for Effective Therapy in Cancer Cells.
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Targeted knockdown of Bcl2 in tumor cells using a synthetic TRAIL 3'-UTR microRNA.
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Targeted photodynamic therapy agent with a built-in apoptosis sensor for in vivo near-infrared imaging of tumor apoptosis triggered by its photosensitization in situ.
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Targeted Photodynamic Therapy of Human Head and Neck Squamous Cell Carcinoma with Anti-epidermal Growth Factor Receptor Antibody Cetuximab and Photosensitizer IR700DX in the Mouse Skin-fold Window Chamber Model.
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Targeted theranostic platinum(IV) prodrug with a built-in aggregation-induced emission light-up apoptosis sensor for noninvasive early evaluation of its therapeutic responses in situ.
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Targeting AKT with the proapoptotic peptide, TAT-CTMP: A novel strategy for the treatment of human pancreatic adenocarcinoma.
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Targeting Cancer Cell Metabolism with Metformin, Dichloroacetate and Memantine in Glioblastoma (GBM).
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Targeting CD47 and Autophagy Elicited Enhanced Antitumor Effects in Non-Small Cell Lung Cancer.
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Targeting dna double strand break repair with hyperthermia and dna-pkcs inhibition to enhance the effect of radiation treatment.
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Targeting FGFR Pathway in Human Hepatocellular Carcinoma: Expressing pFGFR and pMET for Antitumor Activity.
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Targeting IL-10, ZO-1 gene expression and IL-6/STAT-3 trans-signaling by a combination of atorvastatin and mesalazine to enhance anti-inflammatory effects and attenuates progression of oxazolone-induced colitis.
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Targeting Lyn tyrosine kinase through protein fusions encompassing motifs of Cbp (Csk-binding protein) and the SOCS box of SOCS1.
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Targeting of AML1-ETO in t(8;21) leukemia by oridonin generates a tumor suppressor-like protein.
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Targeting procaspase-3 with WF-208, a novel PAC-1 derivative, causes selective cancer cell apoptosis.
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Targeting the insulin-like growth factor-1 receptor by picropodophyllin for lung cancer chemoprevention.
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Targeting the Somatostatin Receptor 2 with the Miniaturized Drug Conjugate, PEN-221: A Potent and Novel Therapeutic for the Treatment of Small Cell Lung Cancer.
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Targeting the XIAP/caspase-7 complex selectively kills caspase-3-deficient malignancies.
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Tat-SmacN7 induces radiosensitization in cancer cells through the activation of caspases and induction of apoptosis.
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Taurine induces the apoptosis of breast cancer cells by regulating apoptosis-related proteins of mitochondria.
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Tauroursodeoxycholic acid inhibits experimental colitis by preventing early intestinal epithelial cell death.
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Telmisartan prevents aneurysm progression in the rat by inhibiting proteolysis, apoptosis and inflammation.
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Telomerase antagonist imetelstat increases radiation sensitivity in esophageal squamous cell carcinoma.
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Testosterone induces apoptosis in cardiomyocytes by increasing proapoptotic signaling involving tumor necrosis factor-? and renin angiotensin system.
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Tetrahydropteridines suppress gene expression and induce apoptosis of activated RAW264.7 cells via formation of hydrogen peroxide.
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Tetramer formation by the caspase-activated fragment of the Par-4 tumor suppressor.
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Tetrandrine attenuates lipopolysaccharide-induced fulminant hepatic failure in D-galactosamine-sensitized mice.
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TGF-?1 protection against A?1-42-induced hippocampal neuronal inflammation and apoptosis by T?R-I.
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The activity of zoledronic Acid on neuroblastoma bone metastasis involves inhibition of osteoclasts and tumor cell survival and proliferation.
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The ameliorative role of Physalis pubescens L. against neurological impairment associated with streptozotocin induced diabetes in rats.
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The anti-apoptotic activity of BAG3 is restricted by caspases and the proteasome.
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The Anti-Cancer Effects of a Zotarolimus and 5-Fluorouracil Combination Treatment on A549 Cell-Derived Tumors in BALB/c Nude Mice.
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The anti-inflammatory and anti-apoptotic effects of nesfatin-1 in the traumatic rat brain.
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The anti-tumor activities of cerebrosides derived from sea cucumber Acaudina molpadioides and starfish Asterias amurensis in vitro and in vivo.
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The anti-tumor effect of fibrin glue containing temozolomide against malignant glioma.
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The anti-tumor properties of two tumstatin peptide fragments in human gastric carcinoma.
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The antidepressant amitriptyline shows potent therapeutic activity against multiple myeloma.
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THE ANTIOXIDANT AND ANTIAPOPTOTIC EFFECT OF BORIC ACID ON HEPATOXICITY IN CHRONIC ALCOHOL-FED RATS.
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The antipsychotic agent trifluoperazine hydrochloride suppresses triple-negative breast cancer tumor growth and brain metastasis by inducing G0/G1 arrest and apoptosis.
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The antitumor effect of folic acid conjugated-Auricularia auricular polysaccharide-cisplatin complex on cervical carcinoma cells in nude mice.
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The antitumor effect of suicide gene therapy using Bifidobacterium infantis-mediated herpes simplex virus thymidine kinase/ganciclovir in a nude mice model of renal cell carcinoma.
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The bioactive ingredients in Actinidia chinensis Planch. Inhibit liver cancer by inducing apoptosis.
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The biochemical and morphological alterations following administration of melatonin, retinoic acid and Nigella sativa in mammary carcinoma: an animal model.
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The Birc6 (Bruce) gene regulates p53 and the mitochondrial pathway of apoptosis and is essential for mouse embryonic development.
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The Caspase-3/PKC?/Akt/VEGF-A Signaling Pathway Mediates Tumor Repopulation during Radiotherapy.
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The Chemokine Platelet factor-4 variant (PF-4var)/CXCL4L1 Inhibits Diabetes-induced Blood-retinal Barrier Breakdown.
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The chemopreventive effect of thymol against dimethylhydrazine and/or high fat diet-induced colon cancer in rats: Relevance to NF-?B.
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The combination effects of Shen-Ling-Bai-Zhu on promoting apoptosis of transplanted H22 hepatocellular carcinoma in mice receiving chemotherapy.
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The combination of everolimus and zoledronic acid increase the efficacy of gemcitabine in a mouse model of pancreatic adenocarcinoma.
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The combination of intravenous Reolysin and gemcitabine induces reovirus replication and endoplasmic reticular stress in a patient with KRAS-activated pancreatic cancer.
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The critical role of autophagy in cadmium-induced immunosuppression regulated by endoplasmic reticulum stress-mediated calpain activation in RAW264.7 mouse monocytes.
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The cyclin-dependent kinase inhibitor roscovitine and the nucleoside analog sangivamycin induce apoptosis in caspase-3 deficient breast cancer cells independent of caspase mediated P-glycoprotein cleavage: implications for therapy of drug resistant breast cancers.
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The cyclooxygenase-2 inhibitor celecoxib induces apoptosis by blocking Akt activation in human prostate cancer cells independently of Bcl-2.
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The cyclooxygenase-2 inhibitor NS-398 inhibits proliferation and induces apoptosis in human osteosarcoma cells via downregulation of the survivin pathway.
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The cytoprotective effects of addition of activated protein C into preservation solution on small-for-size grafts in rats.
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The cytotoxic effect of Eucheuma serra agglutinin (ESA) on cancer cells and its application to molecular probe for drug delivery system using lipid vesicles.
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The death of human cancer cells following photodynamic therapy: apoptosis competence is necessary for Bcl-2 protection but not for induction of autophagy.
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The dietary flavonol fisetin enhances the apoptosis-inducing potential of TRAIL in prostate cancer cells.
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The dual anti-inflammatory and antioxidant activities of natural honey promote cell proliferation and neural regeneration in a rat model of colitis.
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The E3 Ubiquitin Ligase ARIH1 Protects against Genotoxic Stress by Initiating a 4EHP-Mediated mRNA Translation Arrest.
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The Effect of CASP3 rs4647610 and rs4647602 Polymorphisms on Tumour Size and Cancer Stage in Papillary Thyroid Carcinoma.
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The effect of cyclosporin on cell division and apoptosis in human oral keratinocytes.
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The effect of MEK1/2 inhibitors on cisplatin-induced acute kidney injury (AKI) and cancer growth in mice.
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The Effect of Pentoxifylline on Passive Avoidance Learning and Expression of Tumor Necrosis Factor-Alpha and Caspase-3 in the Rat Hippocampus Following Lipopolysaccharide-Induced Inflammation.
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The effect of quercetin nanoparticle on cervical cancer progression by inducing apoptosis, autophagy and anti-proliferation via JAK2 suppression.
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The effect of salmon calcitonin against glutamate-induced cytotoxicity in the C6 cell line and the roles the inflammatory and nitric oxide pathways play.
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The effect of sildenafil on right ventricular remodeling in a rat model of monocrotaline-induced right ventricular failure.
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The effect of white tea on serum TNF-?/NF-?B and immunohistochemical parameters in cisplatin-related renal dysfunction in female rats.
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The effects of a polyphenol present in olive oil, oleuropein aglycone, in an experimental model of spinal cord injury in mice.
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The effects of dihydroxyphenyl lactic acid on alleviating blood-brain barrier injury following subarachnoid hemorrhage in rats.
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The effects of safranal, a constitute of saffron, and metformin on spatial learning and memory impairments in type-1 diabetic rats: behavioral and hippocampal histopathological and biochemical evaluations.
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The Effects of Selenium in Acrylamide-Induced Nephrotoxicity in Rats: Roles of Oxidative Stress, Inflammation, Apoptosis, and DNA Damage.
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The effects of vitamin A supplementation for 3 months on adult rat nigrostriatal axis: Increased monoamine oxidase enzyme activity, mitochondrial redox dysfunction, increased ?-amyloid(1-40) peptide and TNF-? contents, and susceptibility of mitochondria to an in vitro H(2)O(2) challenge.
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The efficacy of oleuropein against non-steroidal anti-inflammatory drug induced toxicity in rat kidney.
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The Escalation of Osteosarcoma Stem Cells Apoptosis After the Co-Cultivation of Peripheral Blood Mononuclear Cells Sensitized with Mesenchymal Stem Cells Secretome and Colony Stimulating Factor-2 in vitro.
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The essential role of the mitochondria-dependent death-signaling cascade in chemotherapy-induced potentiation of Apo2L/TRAIL cytotoxicity in cultured thoracic cancer cells: amplified caspase 8 is indispensable for combination-mediated massive cell death.
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The expression of AIB1 correlates with cellular proliferation in human prolactinomas.
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The extrinsic apoptotic signaling pathway in gastric adenocarcinomas assessed by tissue microarray.
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The Fractionated Toona sinensis Leaf Extract Induces Apoptosis of Human Osteosarcoma Cells and Inhibits Tumor Growth in a Murine Xenograft Model.
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The Growing Complexity of Cancer Cell Response to DNA-Damaging Agents: Caspase 3 Mediates Cell Death or Survival?
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The growth inhibitory effect of mesenchymal stem cells on tumor cells in vitro and in vivo.
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The HDAC inhibitor panobinostat (LBH589) inhibits mesothelioma and lung cancer cells in vitro and in vivo with particular efficacy for small cell lung cancer.
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The hepatitis B virus-X protein activates a phosphatidylinositol 3-kinase-dependent survival signaling cascade.
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The Hepatoprotective Effect of Haoqin Qingdan Decoction against Liver Injury Induced by a Chemotherapeutic Drug Cyclophosphamide.
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The histone deacetylase inhibitor vorinostat selectively sensitizes fibrosarcoma cells to chemotherapy.
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The Identification of a Novel Unsymmetrical Azine as an Apoptosis Inducer in Colorectal Cancer.
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The in vitro and in vivo antitumor activity of adenovirus-mediated interleukin-24 expression for laryngocarcinoma.
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The in vivo anti-leukemia activity of N-(1-Pyrenlyl) maleimide in a bioluminescent mouse model.
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The inducing of caspase and Bcl-2 pathway with royal jelly decreases the muscle tissue damage exposed with fluoride in rats.
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The induction of autophagy against mitochondria-mediated apoptosis in lung cancer cells by a ruthenium (II) imidazole complex.
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The induction of the TNFalpha death domain signaling pathway in Alzheimer's disease brain.
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The induction of tumor apoptosis in B16 melanoma following STAT3 siRNA delivery with a lipid-substituted polyethylenimine.
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The influence of early hemodynamic optimization on biomarker patterns of severe sepsis and septic shock.
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The Inhibitory Effects of Recombinant Hespintor Combined with Sorafenib on Transplanted Human Hepatoma in Nude Mice, and Transcriptional Regulation of Hespintor Based on RNA-Seq.
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The Inhibitory Efficacy of Methylseleninic Acid Against Colon Cancer Xenografts in C57BL/6 Mice.
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The Interaction between Reactive Peritoneal Mesothelial Cells and Tumor Cells via Extracellular Vesicles Facilitates Colorectal Cancer Dissemination.
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The interaction between the light source dose and caspase-dependent and -independent apoptosis in human SK-MEL-3 skin cancer cells following photodynamic therapy with zinc phthalocyanine: A comparative study.
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The interrelationship between gasotransmitters and lead-induced renal toxicity in rats.
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The interrelationship between HER2 and CASP3/8 with apoptosis in different cancer cell lines.
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The involvement of TNF-alpha-related apoptosis-inducing ligand in the enhanced cytotoxicity of IFN-beta-stimulated human dendritic cells to tumor cells.
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The latex sap of the 'Old World Plant' Lagenaria siceraria with potent lectin activity mitigates neoplastic malignancy targeting neovasculature and cell death.
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The long noncoding RNA XIAP-AS1 promotes XIAP transcription by XIAP-AS1 interacting with Sp1 in gastric cancer cells.
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The lower intestinal tract-specific induction of heme oxygenase-1 by glutamine protects against endotoxemic intestinal injury.
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The marine alkaloid naamidine A promotes caspase-dependent apoptosis in tumor cells.
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The mechanism of and the association between interleukin-27 and chemotherapeutic drug sensitivity in lung cancer.
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The mechanism of PDA/PEI/5-Fu coated esophageal stent material on inhibiting cancer associated pathological cells.
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The mechanisms of baicalin ameliorate obesity and hyperlipidemia through a network pharmacology approach.
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The Membrane-Bound Form of IL-17A Promotes the Growth and Tumorigenicity of Colon Cancer Cells.
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The Microbiota-Derived Metabolite of Quercetin, 3,4-Dihydroxyphenylacetic Acid Prevents Malignant Transformation and Mitochondrial Dysfunction Induced by Hemin in Colon Cancer and Normal Colon Epithelia Cell Lines.
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The mitochondria-targeting antioxidant MitoQ alleviated Lipopolysaccharide/ D-galactosamine-induced acute liver injury in mice.
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The mitochondrial permeability transition is required for tumor necrosis factor alpha-mediated apoptosis and cytochrome c release.
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The mixed human umbilical cord blood-derived mesenchymal stem cells show higher antitumor effect against C6 cells than the single in vitro.
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The mycotoxin fumonisin B1 transiently activates nuclear factor-kappaB, tumor necrosis factor alpha and caspase 3 via protein kinase Calpha-dependent pathway in porcine renal epithelial cells.
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The neuroprotective effects of Tao-Ren-Cheng-Qi Tang against embolic stroke in rats.
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The new-generation proteasome inhibitor oprozomib increases the sensitivity of cervical cancer cells to cisplatin-induced apoptosis.
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The newly synthesized anticancer drug HUHS1015 is useful for treatment of human gastric cancer.
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The nitrosteroid NCX 1015, a prednisolone derivative, improves recovery of function in rats after spinal cord injury.
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The nonthiazolidinedione tyrosine-based peroxisome proliferator-activated receptor gamma ligand GW7845 induces apoptosis and limits migration and invasion of rat and human glioma cells.
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The novel Akt inhibitor Palomid 529 (P529) enhances the effect of radiotherapy in prostate cancer.
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The Novel Histone Deacetylase Inhibitor, OBP-801, Induces Apoptosis in Rhabdoid Tumors by Releasing the Silencing of NOXA.
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The novel HSP90 inhibitor STA-1474 exhibits biologic activity against osteosarcoma cell lines.
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The novel indole compound SK228 induces apoptosis and FAK/Paxillin disruption in tumor cell lines and inhibits growth of tumor graft in the nude mouse.
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The novel mechanism of anticancer effect on gastric cancer through inducing G0/G1 cell cycle arrest and caspase-dependent apoptosis in vitro and in vivo by methionine enkephalin.
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The novel melphalan prodrug J1 inhibits neuroblastoma growth in vitro and in vivo.
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The novel SOD mimetic GC4419 increases cancer cell killing with sensitization to ionizing radiation while protecting normal cells.
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The novel strategy for concurrent chemoradiotherapy by conjugating the apoptotic cell-binding moiety to caspase-3 activated doxorubicin prodrug.
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The novel thiosemicarbazone, di-2-pyridylketone 4-cyclohexyl-4-methyl-3-thiosemicarbazone (DpC), inhibits neuroblastoma growth in vitro and in vivo via multiple mechanisms.
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The pattern of CPP32/caspase-3 expression reflects the biological behavior of the human pancreatic duct cell tumors.
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The PI3K-NF-kappaB signal transduction pathway is involved in mediating the anti-inflammatory effect of IB-MECA in adjuvant-induced arthritis.
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The Possible Contribution of P-Glycoprotein in the Protective Effect of Paeonol against Methotrexate-Induced Testicular Injury in Rats.
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The potential curative effect of rebamipide in hepatic ischemia/reperfusion injury.
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The potential protective and therapeutic effects of platelet-rich plasma on ischemia/reperfusion injury following experimental torsion/detorsion of testis in the Albino rat model.
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The potential protective effect of modafinil in intestinal ischemic reperfusion-induced in rats.
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The Potential Protective Effects of Diosmin on Streptozotocin-Induced Diabetic Cardiomyopathy in Rats.
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The potential relationship between gasotransmitters and oxidative stress, inflammation and apoptosis in lead-induced hepatotoxicity in rats.
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The potential toxicity of food-added sodium benzoate in mice is concentration-dependent.
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The Potentized Homeopathic Drug, Lycopodium clavatum (5C and 15C) Has Anti-cancer Effect on HeLa Cells In Vitro.
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The Pro-Apoptotic Activity of Tamarixetin on Liver Cancer Cells Via Regulation Mitochondrial Apoptotic Pathway.
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The proapoptotic tumor suppressor protein kinase C-delta is lost in human squamous cell carcinomas.
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The proinflammatory cytokine interleukin-18 alters multiple signaling pathways to inhibit natural killer cell death.
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The promising effects of BMP2 transfected mesenchymal stem cells on human osteosarcoma.
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The protective activity of mesothelial cells against peritoneal growth of gastrointestinal tumors: The role of soluble ICAM-1.
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The protective effect of cannabinoid type 2 receptor activation on renal ischemia-reperfusion injury.
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The protective effects of angiotensin-converting enzyme inhibitor against cecal ligation and puncture-induced sepsis via oxidative stress and inflammation.
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The protective effects of sumatriptan on vincristine - induced peripheral neuropathy in a rat model.
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The protective mechanism underlying total flavones of Dracocephalum (TFD) effects on rat cerebral ischemia reperfusion injury.
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The retinoid derivant ECPIRM selectively exhibited anti-proliferation effects in cutaneous T-Cell lymphoma via ITK-mediated signaling pathway.
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The rigid steroid 21-hydroxy-6,19-epoxyprogesterone (21OH-6,19OP) is a dissociated glucocorticoid receptor modulator potentially useful as a novel coadjuvant in breast cancer chemotherapy.
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The role of caspase family protease, caspase-3 on cisplatin-induced apoptosis in cisplatin-resistant A431 cell line.
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The role of exosomal miR-375-3p: A potential suppressor in bladder cancer via the Wnt/?-catenin pathway.
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The Role of Pyruvate Dehydrogenase Kinase-4 (PDK4) in Bladder Cancer and Chemoresistance.
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The role of stem cell antigen-1/Lymphocyte antigen 6A-2/6E-1 knock out in murine epidermis.
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The ruthenium complexes cis-(dichloro)tetramineruthenium(III) chloride and cis-tetraammine(oxalato)ruthenium(III) dithionate overcome resistance inducing apoptosis on human lung carcinoma cells (A549).
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The sirtuin 1 activator SRT1720 alleviated endotoxin-induced fulminant hepatitis in mice.
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The small heat shock protein alpha B-crystallin is a novel inhibitor of TRAIL-induced apoptosis that suppresses the activation of caspase-3.
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The splicing FK506-binding protein-51 isoform plays a role in glioblastoma resistance through programmed cell death ligand-1 expression regulation.
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The study of effect and mechanism of 630-nm laser on human lung adenocarcinoma cell xenograft model in nude mice mediated by hematoporphyrin derivatives.
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The suppression of torulene and torularhodin treatment on the growth of PC-3 xenograft prostate tumors.
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The synthetic retinoid adapalene inhibits proliferation and induces apoptosis in colorectal cancer cells in vitro.
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The thalidomide analogue, CC-4047, induces apoptosis signaling and growth arrest in childhood acute lymphoblastic leukemia cells in vitro and in vivo.
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The Therapeutic Potential of Conditioned Medium from Human Breast Milk Stem Cells in Treating Spinal Cord Injury.
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The therapeutic role of inhibition of miR-328 on pulmonary carcinoma induced by chlamydia pneumoniae through targeting histone H2AX.
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The Tomato Glycoalkaloid ?-Tomatine Induces Caspase-Independent Cell Death in Mouse Colon Cancer CT-26 Cells and Transplanted Tumors in Mice.
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The tyrphostin AG1478 inhibits proliferation and induces death of liver tumor cells through EGF receptor-dependent and independent mechanisms.
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The Underlying Mechanism of Paeonia lactiflora Pall. in Parkinson's Disease Based on a Network Pharmacology Approach.
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The up-regulated lncRNA DLX6-AS1 in colorectal cancer promotes cell proliferation, invasion and migration via modulating PI3K/AKT/mTOR pathway.
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The upregulated ?-catulin expression was involved in head-neck squamous cell carcinogenesis by promoting proliferation, migration, invasion, and epithelial to mesenchymal transition.
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Therapeutic effect and apoptosis mechanism of lung-tonifying and expectorant decoction on lung cancer rats with Qi deficiency and blood stasis.
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Therapeutic Effect of IL-4 Receptor-Targeting Pro-Apoptotic Peptide (AP1-ELP-KLAK) in Glioblastoma Tumor Model.
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Therapeutic effect of methylprednisolone combined with high frequency electrotherapy on acute spinal cord injury in rats.
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Therapeutic Effect of Supercritical CO2 Extracts of Curcuma Species with Cancer Drugs in Rhabdomyosarcoma Cell Lines.
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Therapeutic effect of urine-derived stem cells for protamine/lipopolysaccharide-induced interstitial cystitis in a rat model.
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Therapeutic efficacy of PUMA for malignant glioma cells regardless of p53 status.
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Therapeutic potential of new 4-hydroxy-tamoxifen-loaded pH-gradient liposomes in a multiple myeloma experimental model.
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Therapy of Smac mimetic SM-164 in combination with gemcitabine for pancreatic cancer.
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Thiamine Alleviates High-Concentrate-Diet-Induced Oxidative Stress, Apoptosis, and Protects the Rumen Epithelial Barrier Function in Goats.
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Thiazolidinedione "Magic Bullets" Simultaneously Targeting PPAR? and HDACs: Design, Synthesis, and Investigations of their In Vitro and In Vivo Antitumor Effects.
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Thioredoxin-Interacting Protein: a Novel Target for Neuroprotection in Experimental Thromboembolic Stroke in Mice.
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Three apoptotic genes are upregulated in a patient with Alzheimer's disease and well-differentiated squamous cell carcinoma.
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Three phytosterols from sweet potato inhibit MCF7-xenograft-tumor growth through modulating gut microbiota homeostasis and SCFAs secretion.
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Three-dimensional culture of mouse renal carcinoma cells in agarose macrobeads selects for a subpopulation of cells with cancer stem cell or cancer progenitor properties.
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Thrombospondin-1-induced apoptosis of brain microvascular endothelial cells can be mediated by TNF-R1.
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Thymoquinone ameliorates testicular tissue inflammation induced by chronic administration of oral sodium nitrite.
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Thymoquinone as an anticancer agent: evidence from inhibition of cancer cells viability and invasion in vitro and tumor growth in vivo.
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Thymoquinone enhances cisplatin-response through direct tumor effects in a syngeneic mouse model of ovarian cancer.
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Thymoquinone reduces mouse colon tumor cell invasion and inhibits tumor growth in murine colon cancer models.
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Thymoquinone reduces spinal cord injury by inhibiting inflammatory response, oxidative stress and apoptosis via PPAR-? and PI3K/Akt pathways.
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Thyroid status modulates T lymphoma growth via cell cycle regulatory proteins and angiogenesis.
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Time course of apoptotic tumor response after a single dose of chemotherapy: comparison with 99mTc-annexin V uptake and histologic findings in an experimental model.
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Time course of Paclitaxel-induced apoptosis in an experimental model of virus-induced breast cancer.
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Time course profiling of the retinal transcriptome after optic nerve transection and optic nerve crush.
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Time-lapse observation of cellular function with fluorescent probe reveals novel CTL-target cell interactions.
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Tissue responses to hexyl 5-aminolevulinate-induced photodynamic treatment in syngeneic orthotopic rat bladder cancer model: possible pathways of action.
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TNF potentiates anticancer activity of bortezomib (Velcade) through reduced expression of proteasome subunits and dysregulation of unfolded protein response.
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TNF-? produced by SEC2 mutant (SAM-3)-activated human T cells induces apoptosis of HepG2 cells.
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TNF-alpha stimulates caspase-3 activation and apoptotic cell death in primary septo-hippocampal cultures.
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TNF?-induced lysosomal membrane permeability is downstream of MOMP and triggered by caspase-mediated NDUFS1 cleavage and ROS formation.
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TNFAIP8 Deficiency Exacerbates Acute Graft Versus Host Disease in a Murine Model of Allogeneic Hematopoietic Cell Transplantation.
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Toll like receptor 4 signaling pathway participated in Salmonella lipopolysaccharide-induced spleen injury in young chicks.
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Toll-like receptor 4 mediates the antitumor host response induced by Ganoderma atrum polysaccharide.
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Toxicity of Pekinenin C from Euphorbia Pekinensis Radix on Rat Small Intestinal Crypt Epithelial Cell and Its Apoptotic Mechanism.
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TPGS/Phospholipids Mixed Micelles for Delivery of Icariside II to Multidrug-Resistant Breast Cancer.
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Traditional Chinese medicine, Xue-Fu-Zhu-Yu decoction, potentiates tissue plasminogen activator against thromboembolic stroke in rats.
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Transcatheter arterial chemoembolization (TACE) with iRGD peptide in rabbit VX2 liver tumor.
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Transcript expression and genetic variability analysis of caspases in breast carcinomas suggests CASP9 as the most interesting target.
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Transcriptome profile analysis reveals cardiotoxicity of maduramicin in primary chicken myocardial cells.
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Transcutaneous application of carbon dioxide (CO2) induces mitochondrial apoptosis in human malignant fibrous histiocytoma in vivo.
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Transduction motif analysis of gastric cancer based on a human signaling network.
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Transferrin-Conjugated Erianin-Loaded Liposomes Suppress the Growth of Liver Cancer by Modulating Oxidative Stress.
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Transferrin-conjugated liposomes loaded with carnosic acid inhibit liver cancer growth by inducing mitochondria-mediated apoptosis.
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Transferrin-Functionalized Microemulsions Coloaded with Coix Seed Oil and Tripterine Deeply Penetrate To Improve Cervical Cancer Therapy.
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Transformation of patchouli alcohol to ?-patchoulene by gastric juice: ?-patchoulene is more effective in preventing ethanol-induced gastric injury.
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Transglutaminase 2 suppresses apoptosis by modulating caspase 3 and NF-kappaB activity in hypoxic tumor cells.
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Transient Exposure of Mammary Tumors to PD184352 and UCN-01 Causes Tumor Cell Death In Vivo and Prolonged Suppression of Tumor Regrowth.
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Translational regulation of XIAP expression and cell survival during hypoxia in human cholangiocarcinoma.
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Transplantation of a Novel Recombinant Adeno-Associated Virus (pAAV-HE1B19K-TE1A) Demonstrates Higher Anti-Tumor Effects in Tumor Cells.
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Transplantation of viable mitochondria attenuates neurologic injury after spinal cord ischemia.
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Treadmill Running Improves Spatial Learning Memory Through Inactivation of Nuclear Factor Kappa B/Mitogen-Activated Protein Kinase Signaling Pathway in Amyloid-?-Induced Alzheimer Disease Rats.
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Treatment of chronic kidney disease using a traditional Chinese medicine, Flos Abelmoschus manihot (Linnaeus) Medicus (Malvaceae).
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Treatment of undifferentiated colorectal cancer cells with fish-oil derived docosahexaenoic acid triggers caspase-3 activation and apoptosis.
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Treatment with catalpol protects against cisplatin-induced renal injury through Nrf2 and NF-?B signaling pathways.
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Treatment with ginseng total saponins reduces the secondary brain injury in rat after cortical impact.
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Treatment-induced tumor cell apoptosis following high-intensity interval training and saffron aqueous extract in mice with breast cancer.
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Trehalose enhances the antitumor potential of methotrexate against mice bearing Ehrlich ascites carcinoma.
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Triacontanoic ester of 5''-hydroxyjustisolin: Tumour suppressive role in cervical cancer via Bcl-2, BAX and caspase-3 mediated signalling.
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Trichosanthin cooperates with Granzyme B to restrain tumor formation in tongue squamous cell carcinoma.
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Trichosanthin inhibits breast cancer cell proliferation in both cell lines and nude mice by promotion of apoptosis.
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Trichothecin induces cell death in NF-?B constitutively activated human cancer cells via inhibition of IKK? phosphorylation.
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Triclabendazole Induces Pyroptosis by Activating Caspase-3 to Cleave GSDME in Breast Cancer Cells.
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Trimodal cancer treatment: beneficial effects of combined antiangiogenesis, radiation, and chemotherapy.
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Triptolide circumvents drug-resistant effect and enhances 5-fluorouracil antitumor effect on KB cells.
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Triptolide modulates tumour-colonisation and anti-tumour effect of attenuated Salmonella encoding DNase I.
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Triptolide sensitizes cisplatin-resistant human epithelial ovarian cancer by inhibiting the phosphorylation of AKT.
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Tualang Honey Reduced Neuroinflammation and Caspase-3 Activity in Rat Brain after Kainic Acid-Induced Status Epilepticus.
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Tumor apoptosis induced by ruthenium(II)-ketoconazole is enhanced in nonsusceptible carcinoma by monoclonal antibody to EGF receptor.
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Tumor cell sensitization to apoptotic stimuli by selective inhibition of specific Akt/PKB family members.
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Tumor cell-released autophagosomes (TRAP) enhance apoptosis and immunosuppressive functions of neutrophils.
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Tumor cells expressing a fusion protein of MULT1 and Fas are rejected in vivo by apoptosis and NK cell activation.
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Tumor control in a model of bone marrow transplantation and acute liver-infiltrating B-cell lymphoma: an unpredicted novel function of cytomegalovirus.
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Tumor development in rats and cancer cachexia are reduced by treatment with botryosphaeran by increasing apoptosis and improving the metabolic profile.
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Tumor growth suppressive effect of IL-4 through p21-mediated activation of STAT6 in IL-4R? overexpressed melanoma models.
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Tumor necrosis factor-? disruption of brain endothelial cell barrier is mediated through matrix metalloproteinase-9.
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Tumor necrosis factor-alpha-induced apoptosis in olfactory epithelium in vitro: possible roles of caspase 1 (ICE), caspase 2 (ICH-1), and caspase 3 (CPP32).
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Tumor necrosis factor-related apoptosis-inducing ligand inhibits the growth and aggressiveness of colon carcinoma via the exogenous apoptosis signaling pathway.
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Tumor regression induced by photodynamic treatment with chlorin p(6) in hamster cheek pouch model of oral carcinogenesis: Dependence of mode of tumor cell death on the applied drug dose.
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Tumor regression mechanisms by IL-13 receptor-targeted cancer therapy involve apoptotic pathways.
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Tumor suppressor p53 induces apoptosis of host lymphocytes experimentally infected by Leishmania major, by activation of Bax and caspase-3: a possible survival mechanism for the parasite.
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Tumor-induced apoptosis of T lymphocytes: elucidation of intracellular apoptotic events.
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Tumor-infiltrated immune response correlates with alterations in the apoptotic and cell cycle pathways in Hodgkin and Reed-Sternberg cells.
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Tumor-specific gene expression using the survivin promoter is further increased by hypoxia.
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Tumor-targeting, pH-sensitive nanoparticles for docetaxel delivery to drug-resistant cancer cells.
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Tumoral response and tumoral phenotypic changes in a rat model of diethylnitrosamine-induced hepatocellular carcinoma after salirasib and sorafenib administration.
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Tumoricidal activity of combining the agonistic DR5 antibody D-6 with cisplatin in C30 cisplatin-resistant ovarian cancer in vitro and in vivo.
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Tumour necrosis factor-alpha- vs. growth factor deprivation-promoted cell death: different receptor requirements for mediating nerve growth factor-promoted rescue.
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Tumour necrosis factor-related apoptosis-inducing ligand (TRAIL) loss in canine mammary carcinoma.
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Tuning of apoptosis-mediator gene transcription in HepG2 human hepatoma cells through an adenosine signal.
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Tuning of mRNA stability through altering 3'-UTR sequences generates distinct output expression in a synthetic circuit driven by p53 oscillations.
Neoplasms
Turmeric and vitamin C mitigate testicular atrophy induced by lead diacetate via regulation of GRP-78/17?-HSD pathways in rat's model.
Neoplasms
Two novel compounds of vanadium and molybdenum with carnitine exhibiting potential pharmacological use.
Neoplasms
Two Trichothecene Mycotoxins from Myrothecium roridum Induce Apoptosis of HepG-2 Cells via Caspase Activation and Disruption of Mitochondrial Membrane Potential.
Neoplasms
Two-photon imaging of intratumoral CD8 T cell cytotoxic activity during adoptive T cell therapy in mice.
Neoplasms
U1 Adaptors suppress the KRAS-MYC oncogenic axis in human pancreatic cancer xenografts.
Neoplasms
Ubiquitin-Associated (UBA) Domain in Human Fas Associated Factor 1 Inhibits Tumor Formation by Promoting Hsp70 Degradation.
Neoplasms
Ulinastatin attenuates isoflurane-induced cognitive dysfunction in aged rats by inhibiting neuroinflammation and ?-amyloid peptide expression in the brain.
Neoplasms
Ultrasound-induced release of GDNF from lipid coated microbubbles injected into striatum reduces hypoxic-ischemic injury in neonatal rats.
Neoplasms
Unbiased selection of bone marrow derived cells as carriers for cancer gene therapy.
Neoplasms
Understanding the mechanism of amygdalin's multifunctional anti-cancer action using computational approach.
Neoplasms
Unveiling the role of novel biogenic functionalized CuFe hybrid nanocomposites in boosting anticancer, antimicrobial and biosorption activities.
Neoplasms
Up-regulation of autophagy is a mechanism of resistance to chemotherapy and can be inhibited by pantoprazole to increase drug sensitivity.
Neoplasms
Up-regulation of Tight-Junction Proteins by p38 Mitogen-Activated Protein Kinase/p53 Inhibition Leads to a Reduction of Injury to the Intestinal Mucosal Barrier in Severe Acute Pancreatitis.
Neoplasms
Up-regulation of tumor necrosis factor-? pathway survival genes and of the receptor TNFR2 in gastric cancer.
Neoplasms
Up-regulation of UVRAG by HDAC1 Inhibition Attenuates 5FU-induced Cell Death in HCT116 Colorectal Cancer Cells.
Neoplasms
Upregulated microRNA-31 inhibits oxidative stress-induced neuronal injury through the JAK/STAT3 pathway by binding to PKD1 in mice with ischemic stroke.
Neoplasms
Upregulation of CASP genes in human tumor cells undergoing etoposide-induced apoptosis.
Neoplasms
Upregulation of caspase-3 expression in esophageal cancer correlates with favorable prognosis: an immunohistochemical study from a high incidence area in northern China.
Neoplasms
Upregulation of heme oxygenase-1 with hemin prevents D-galactosamine and lipopolysaccharide-induced acute hepatic injury in rats.
Neoplasms
Upregulation of let-7f-5p promotes chemotherapeutic resistance in colorectal cancer by directly repressing several pro-apoptotic proteins.
Neoplasms
Upregulation Of miR-149-3p Suppresses Spinal Chordoma Malignancy By Targeting Smad3.
Neoplasms
Ursolic acid inhibits proliferation and induces apoptosis of cancer cells in vitro and in vivo.
Neoplasms
Ursolic acid inhibits the initiation, progression of prostate cancer and prolongs the survival of TRAMP mice by modulating pro-inflammatory pathways.
Neoplasms
Ursolic acid inhibits tumor angiogenesis and induces apoptosis through mitochondrial-dependent pathway in Ehrlich ascites carcinoma tumor.
Neoplasms
Use of interfering RNA to investigate the role of endogenous gastrin in the survival of gastrointestinal cancer cells.
Neoplasms
Use of Molecular Biomarkers to Quantify the Spatial Distribution of Effects of Anticancer Drugs in Solid Tumors.
Neoplasms
Use of rhenium-188 for in vivo imaging and treatment of human cervical cancer cells transfected with lentivirus expressing sodium iodide symporter.
Neoplasms
Using Pharmacokinetic Profiles and Digital Quantification of Stained Tissue Microarrays as a Medium-Throughput, Quantitative Method for Measuring the Kinetics of Early Signaling Changes Following Integrin-Linked Kinase Inhibition in an In Vivo Model of Cancer.
Neoplasms
Utility of a Novel Three-Dimensional and Dynamic (3DD) Cell Culture System for PK/PD Studies: Evaluation of a Triple Combination Therapy at Overcoming Anti-HER2 Treatment Resistance in Breast Cancer.
Neoplasms
UV-Emitting Upconversion-Based TiO2 Photosensitizing Nanoplatform: Near-Infrared Light Mediated in Vivo Photodynamic Therapy via Mitochondria-Involved Apoptosis Pathway.
Neoplasms
Vaccarin alleviates hypertension and nephropathy in renovascular hypertensive rats.
Neoplasms
Vaccine-stimulated, adoptively transferred CD8+ T cells traffic indiscriminately and ubiquitously while mediating specific tumor destruction.
Neoplasms
Vagus nerve mediates the protective effects of melanocortins against cerebral and systemic damage after ischemic stroke.
Neoplasms
Vagus nerve stimulation attenuates myocardial ischemia/reperfusion injury by inhibiting the expression of interleukin-17A.
Neoplasms
Valproic acid triggers radiation-induced abscopal effect by modulating the unirradiated tumor immune microenvironment in a rat model of breast cancer.
Neoplasms
Vanillin mitigates the adverse impact of cisplatin and methotrexate on rat kidneys.
Neoplasms
Variation within three apoptosis associated genes as potential risk factors for Achilles tendinopathy in a British based case-control cohort.
Neoplasms
Vasculogenic mimicry: Possible role of effector caspase-3, caspase-6 and caspase-7.
Neoplasms
Vasoactive intestinal peptide inhibits TNF-alpha-induced apoptotic events in acinar cells from nonobese diabetic mice submandibular glands.
Neoplasms
Vasoinhibin, an N-terminal Prolactin Fragment, Directly Inhibits Cardiac Angiogenesis in Three-dimensional Heart Culture.
Neoplasms
VEGI, a new member of the TNF family activates nuclear factor-kappa B and c-Jun N-terminal kinase and modulates cell growth.
Neoplasms
Venlafaxine Mitigates Depressive-Like Behavior in Ovariectomized Rats by Activating the EPO/EPOR/JAK2 Signaling Pathway and Increasing the Serum Estradiol Level.
Neoplasms
Venous congestion induces mucosal apoptosis via tumor necrosis factor-alpha-mediated cell death in the rat small intestine.
Neoplasms
Verapamil augments the neuroprotectant action of berberine in rat model of transient global cerebral ischemia.
Neoplasms
Verbascoside Inhibits Glioblastoma Cell Proliferation, Migration and Invasion While Promoting Apoptosis Through Upregulation of Protein Tyrosine Phosphatase SHP-1 and Inhibition of STAT3 Phosphorylation.
Neoplasms
Verticillin A Inhibits Leiomyosarcoma and Malignant Peripheral Nerve Sheath Tumor Growth via Induction of Apoptosis.
Neoplasms
Viability Assessment Following Anticancer Treatment Requires Single-Cell Visualization.
Neoplasms
Vinpocetine ameliorates L-arginine induced acute pancreatitis via Sirt1/Nrf2/TNF pathway and inhibition of oxidative stress, inflammation, and apoptosis.
Neoplasms
Visible light-induced apoptosis activatable nanoparticles of photosensitizer-DEVD-anticancer drug conjugate for targeted cancer therapy.
Neoplasms
Vitamin A deficiency in K14E7HPV expressing transgenic mice facilitates the formation of malignant cervical lesions.
Neoplasms
Vitamin A supplementation at pharmacological doses induces nitrosative stress on the hypothalamus of adult Wistar rats.
Neoplasms
Vitexin attenuates acute doxorubicin cardiotoxicity in rats via the suppression of oxidative stress, inflammation and apoptosis and the activation of FOXO3a.
Neoplasms
Vochysia tucanorum Mart. butanol fraction presents antitumoral activity in vivo and prevents the installation of cachexia in solid Ehrlich tumor model.
Neoplasms
Voreloxin, formerly SNS-595, has potent activity against a broad panel of cancer cell lines and in vivo tumor models.
Neoplasms
VP1 of foot-and-mouth disease virus induces apoptosis via the Akt signaling pathway.
Neoplasms
Weightlessness induced apoptosis in normal thyroid cells and papillary thyroid carcinoma cells via extrinsic and intrinsic pathways.
Neoplasms
Wikstromol from Wikstroemia indica induces apoptosis and suppresses migration of MDA-MB-231 cells via inhibiting PI3K/Akt pathway.
Neoplasms
Withaferin A Synergizes the Therapeutic Effect of Doxorubicin through ROS-Mediated Autophagy in Ovarian Cancer.
Neoplasms
Xueshuantong for Injection (Lyophilized, ) Alleviates Streptozotocin-Induced Diabetic Retinopathy in Rats.
Neoplasms
Xueshuantong for Injection Ameliorates Diabetic Nephropathy in a Rat Model of Streptozotocin-Induced Diabetes.
Neoplasms
Young Barley Indicates Antitumor Effects in Experimental Breast Cancer In Vivo and In Vitro.
Neoplasms
YQWY Decoction Improves Myocardial Remodeling via Activating the IL-10/Stat3 Signaling Pathway.
Neoplasms
ZFAS1 knockdown inhibits ?broblast-like synoviocyte proliferation, migration, invasion and inflammation, and promotes apoptosis via miR-3926/FSTL1 in rheumatoid arthritis.
Neoplasms
Zinc inhibits Bax and Bak activation and cytochrome c release induced by chemical inducers of apoptosis but not by death-receptor-initiated pathways.
Neoplasms
Zinc Oxide Nanoparticle Induces Apoptosis in Human Epidermoid Carcinoma Cells Through Reactive Oxygen Species and DNA Degradation.
Neoplasms
Zinc Oxide Nanoparticle Synergizes Sorafenib Anticancer Efficacy with Minimizing Its Cytotoxicity.
Neoplasms
Zinc oxide nanoparticles as a novel anticancer approach; in vitro and in vivo evidence.
Neoplasms
Zinc protoporphyrin IX, a heme oxygenase-1 inhibitor, demonstrates potent antitumor effects but is unable to potentiate antitumor effects of chemotherapeutics in mice.
Neoplasms
Zinc supplementation inhibits hepatic apoptosis in mice subjected to a long-term ethanol exposure.
Neoplasms
Zingerone protects liver and kidney tissues by preventing oxidative stress, inflammation, and apoptosis in methotrexate-treated rats.
Neoplasms
Zirconia Nanoparticles Induce HeLa Cell Death Through Mitochondrial Apoptosis and Autophagy Pathways Mediated by ROS.
Neoplasms
Zoledronic acid prevents the hepatic changes associated with high fat diet in rats; the potential role of mevalonic acid pathway in nonalcoholic steatohepatitis.
Neoplasms
[18F]-C-SNAT4: an improved caspase-3-sensitive nanoaggregation PET tracer for imaging of tumor responses to chemo- and immunotherapies.
Neoplasms
[18F]ML-10 PET imaging fails to assess early response to neoadjuvant chemotherapy in a preclinical model of triple negative breast cancer.
Neoplasms
[6]-Gingerol induces caspase 3 dependent apoptosis and autophagy in cancer cells: Drug-DNA interaction and expression of certain signal genes in HeLa cells.
Neoplasms
[99mTc]Tc-duramycin, a potential molecular probe for early prediction of tumor response after chemotherapy.
Neoplasms
[Adenovirus mediated IL-24 gene expression suppresses gastric cancer cell growth in vitro]
Neoplasms
[Anti-hepatoma effects of Smac analogue Birinapant and its related molecular mechanism].
Neoplasms
[Anti-tumor and immune-modulating effect of Jiawei Sijunzi decoction in mice bearing hepatoma H22 tumor].
Neoplasms
[Anti-tumor effect of monkshood polysaccharide with adriamycin long circulating temperature-sensitive liposome and its mechanism]
Neoplasms
[Antitumor Activity of TRAIL-Mu3 Protein in vitro and in vivo and the Mechanisms].
Neoplasms
[Antitumor effects of AZD2014, a dual mTORC1/2 inhibitor, against human hepatocellular carcinoma xenograft in nude mice].
Neoplasms
[Apoptosis mechanism of taxol combined with resveratrol on human laryngeal carcinoma Hep-2 cells].
Neoplasms
[Aspirin inhibits the proliferation of breast cancer cells via inducing apoptosis and autophagy].
Neoplasms
[Biological implications of the inhibition of survivin by RNA interference in human androgen-independent prostate carcinoma with highly metastatic potential]
Neoplasms
[Caspase-3 expression in the tissues of experimental melanoma and its metastases during matrix metalloproteinase-9 inhibition].
Neoplasms
[Cholinergic anti-inflammatory pathway involves in the neuroprotective effect of huperzine A on sepsis-associated encephalopathy].
Neoplasms
[Construction of autocatalytic caspase-3 driven by amplified human telomerase reverse transcriptase promoter and its enhanced efficacy of inducing apoptosis in human ovarian carcinoma]
Neoplasms
[Development of an experimental model for the study of the effects of cryotherapy on lung tumours]
Neoplasms
[Effect of Fei-Liu-Ping ointment combined with cyclophosphamide on lung cancer cell proliferation and acidic microenvironment].
Neoplasms
[Effect of freeze-dried sea cucumber powder of eastern sea on tumor and immune index of S180-bearing mouse]
Neoplasms
[Effect of fuzheng yiliu granule on H22 tumor cell apoptosis, p53 and caspase-3 gene expression in mice]
Neoplasms
[Effect of moxa-burning heat stimulating Liangmen (ST 21) and Zusanli (ST 36) on proliferation and apoptosis signaling proteins in rats with stress-induced gastric ulcer].
Neoplasms
[Effect of p38MAPK gene silencing on expression of oncogenes and apoptotic genes induced by PM(2.5) in hepatocytes].
Neoplasms
[Effect of phenelzine on the proliferation, apoptosis and histone methylation and acetylation of Molt-4 cells].
Neoplasms
[Effect of quercetin on the expression and growth of caspase-3 in lung adenocarcinoma cancer cell line A549.]
Neoplasms
[Effect of the change of caspase-3 activity on the neoadjuvant chemotherapy-induced apoptosis of large-intestinal carcinoma cells]
Neoplasms
[Effect of ulinastatin on apoptosis in ileal mucosa of rats with hemorrhagic shock.]
Neoplasms
[Effect on induction of differentiation of Tca8113 cells affected by abscisic acid in vitro]
Neoplasms
[Effects of hydrogen inhalation on serum pro-inflammatory factors and intestinal injury in mice with severe sepsis].
Neoplasms
[Effects of indole-3-carbinol on the outcome of tumor and the changes of anti-oxidative system in null mice grafted with nasopharyngeal carcinoma]
Neoplasms
[Effects of interstitial chemotherapy using thermosensitive gel-coated ricin on hepatoma H22-bearing mice.]
Neoplasms
[Effects of Sanchinoside R1 on Growth Invasion and Migration of HL-60 Cells and Survival of AML Model Mice].
Neoplasms
[Expression and clinical significance of caspase-3,survivin and k-ras in non-small cell lung cancer.]
Neoplasms
[Expression and clinical significance of Xiap and Caspase-3 protien in primary epithelia ovarian cancer].
Neoplasms
[Expression and prognostic significance of survivin and caspase-3 in esophageal squamous-cell carcinoma and their relationship with HSPs expression]
Neoplasms
[Expression characteristics of inflammatory and apoptosis factors and regulatory effect of anemoside B4 in mice with acute kidney injury].
Neoplasms
[Expression of Kai1 and FasL in non-small cell lung cancer and its clinicopathological significance.]
Neoplasms
[Expression of survivin and its correlation to angiogenesis in oral squamous cell carcinoma]
Neoplasms
[Expression of tumor necrosis factor-alpha and caspase-3 protein in monocytes adjacent to the invaded Echinococcus multilocularis in liver].
Neoplasms
[Features of a necrotic and inflammatory process in different forms of nonalcoholic fatty liver disease].
Neoplasms
[FUNCTIONAL ACTIVITY OF EHRLICH CARCINOMA CELLS AFTER TREATMENT WITH HYBRID NANOCOMPLEXES CONTAINING ORTHOVANADATES OF RARE-EARTH ELEMENTS, CHOLESTEROL AND LUMINESCENT DYE].
Neoplasms
[Gene apoptosis expression profiles in liver cancer and their comparison to normal peri-cancerous liver tissues]
Neoplasms
[Impact of preoperative drug therapy on the expression of apoptosis markers in colorectal liver metastases].
Neoplasms
[Implication of alternative splice transcripts of caspase-3 and survivin in chemoresistance]
Neoplasms
[In vitro and in vivo inhibitory effect of Ad-ING4 gene on proliferation of human prostate cancer PC-3 cells]
Neoplasms
[Inhibitory effect of knocking down microRNA-221 and microRNA-222 on glioma cell growth in vitro and in vivo]
Neoplasms
[Inhibitory effects of Aspisol on growth of transplanted breast cancer in C3H mice]
Neoplasms
[Inhibitory effects of curcumin on apoptosis of human ovary cancer cell line A2780 and its molecular mechanism]
Neoplasms
[Interleukin 24 inhibits growth and induces apoptosis of osteosarcoma cells MG-63 in vitro and in vivo]
Neoplasms
[Intervention of Catalpol on High-fat Diet Induced Nonalcoholic Fatty Liver Disease in Mice].
Neoplasms
[Knock-down of DAB2 interacting protein (DAB2IP) promotes proliferation and inhibits apoptosis of bladder cancer cells].
Neoplasms
[Mechanism of photodynamic therapy against human esophageal carcinoma xenografts in nude mice]
Neoplasms
[miR-455 Inhibits HepG2 Cell Proliferation and Promotes Apoptosis by Targeting RhoC].
Neoplasms
[NS398 induced apoptosis in pancreatic carcinoma cell strain BxPC-3 through a COX-2-in dependent pathway]
Neoplasms
[PHARMACOLOGICAL CORRECTION OF APOPTOSIS LEVEL OF CORTICAL NEURONS IN AGED HER2/NEU TRANSGENIC MICE].
Neoplasms
[Protective effect of sodium 4-phenylbutyrate on rats with acute respiratory distress syndrome related right ventricular dysfunction by alleviating endoplasmic reticulum stress].
Neoplasms
[Protective effects of short-term and long-term exercise preconditioning on myocardial injury in rats].
Neoplasms
[Regulation of content of cytokines in blood serum and of caspase-3 activity in brains of old rats in model of sharp hypoxic hypoxia with Cortexin and Pinealon].
Neoplasms
[Role of ?-toxin-induced apoptosis of umbilical vein endothelial cells in vertical infection of Staphylococcus aureus L-form].
Neoplasms
[Role of proteins in Fas-mediated apoptosis in tumor cells and lymphocytes co-cultured in vitro]
Neoplasms
[Rosiglitazone and all-trans retinoic acid inhibit human myeloma cell proliferation via apoptosis signaling pathway modulation]
Neoplasms
[Sitagliptin inhibits cell apoptosis and inflammation of renal tissues in diabetic nephropathy model rats].
Neoplasms
[Specific Antitumor Effect of Adeno-Associated Virus Vector Carrying TRAIL Gene under the Control of hTERT Promoter.]
Neoplasms
[Studies on mechanism of myricetin-induced apoptosis in human hepatocellular carcinoma HepG-2 cells]
Neoplasms
[Study on Apoptosis of Oral Squamous Carcinoma Cell line KB and KBv200 induced by Survivin RNAi.]
Neoplasms
[Study on synergistic anti-tumor effect of Shuangdan Capsules combined with 5-FU on hepatocellular carcinoma cells Huh-7 and xenograft mice].
Neoplasms
[Synergistic Effect of 2-deoxy-D-glucose Combined with Hydroxycamptothecin on Apoptosis of Breast Cancer Cells].
Neoplasms
[Synergistic role between rhIL-2 and adriamycin long circulating temperature-sensitive liposome in targeting therapy on tumor.]
Neoplasms
[Targeted tumor suppression by a secreted fusion protein consisting of anti- erbB2 antibody and reversed caspase-3 to SKBr3 cells]
Neoplasms
[Technetium-99m labeled synaptotagmin I C2A detection of paclitaxel-induced apoptosis in non-small cell lung cancer]
Neoplasms
[The effect of caspase-3 inhibitor on the concentrations of serum inflammatory cytokines in sepsis related acute kidney injury induced by peritoneal cavity infection in mice.]
Neoplasms
[The effects of Xuebijing injection on apoptosis and expression of regulatory factors TNF-??NF-?B and Caspase-3 expression in the lung tissues of acute paraquat-induced rats].
Neoplasms
[The efficacy of autocatalytic casapse-3 driven by human telomerase reverse transcriptase promoter on human ovarian carcinoma]
Neoplasms
[The long coding RNA GSTM3TV2 acts an oncogene to promote chemoresistance in pancreatic cancer].
Neoplasms
[The relationship between caspase-3 expression and cell proliferation in rat lung squamous cell carcinoma.]
Neoplasms
[The role of Hsp70 chaperone in the reaction of human leukemic cells to anticancer drugs]
Neoplasms
[The synergism and mechanism of action of rClone30-hDR5 in combination with TRAIL on HCC].
Neoplasms
[Tumor necrosis factor-alpha, caspase-3 expression and hepatocyte apoptosis in fulminanting hepatic failure]
Neoplasms
[Tumor suppression of a constitutively active caspase-3 in the SKBr-3 breast carcinoma xenograft mice model]
Neoplasms
[Up-Regulation of Bax/BCL-2 Ratio by 2-Methoxyestradiol Induces Apoptosis in Lymphoma Raji Cells].
Neoplasms
{beta}2-Microglobulin Is a Signaling and Growth-Promoting Factor for Human Prostate Cancer Bone Metastasis.
Neoplasms, Germ Cell and Embryonal
Failure of activation of caspase-9 induces a higher threshold for apoptosis and cisplatin resistance in testicular cancer.
Neoplasms, Squamous Cell
Association of Casp3 microRNA Target Site (1049216) SNP With the Risk and Progress of Cervical Squamous Cell Carcinoma.
Neoplasms, Squamous Cell
Livin and caspase-3 expression are negatively correlated in cervical squamous cell cancer.
Neoplastic Cells, Circulating
Circulating fragmented nucleosomal DNA and caspase-3 mRNA in patients with lymphoma and myeloma.
Nephritis
A shift in the Bax/Bcl-2 balance may activate caspase-3 and modulate apoptosis in experimental glomerulonephritis.
Nephritis
Apoptosis and caspase-3 in experimental anti-glomerular basement membrane nephritis.
Nephritis
Effects of caspase inhibition on the progression of experimental glomerulonephritis.
Nephrosclerosis
Nipradilol prevents L-NAME-exacerbated nephrosclerosis with decreasing of caspase-3 expression in SHR.
Nervous System Diseases
A facile method to prepare large quantities of active caspase-3 overexpressed by auto-induction in the C41(DE3) strain.
Nervous System Diseases
Deletion of JDP2 improves neurological outcomes of traumatic brain injury (TBI) in mice: Inactivation of Caspase-3.
Nervous System Diseases
Induction of oxidative and nitrosative damage leads to cerebrovascular inflammation in an animal model of mild traumatic brain injury induced by primary blast.
Nervous System Diseases
Neuroprotective effects of novel nitrones: In vitro and in silico studies.
Nervous System Diseases
Selective detection and inhibition of active caspase-3 in cells with optimized peptides.
Neural Tube Defects
Rare mutations inapoptosis related genes APAF1, CASP9, and CASP3 contribute to human neural tube defects.
Neural Tube Defects
The role of cell death in regulating the size and shape of the mammalian forebrain.
Neural Tube Defects
Valproic acid-induced DNA damage increases embryonic p27(KIP1) and caspase-3 expression: A mechanism for valproic-acid induced neural tube defects.
Neuralgia
Restoration of Cingulate Long-Term Depression by Enhancing Non-apoptotic Caspase 3 Alleviates Peripheral Pain Hypersensitivity.
Neuralgia
Sesamol Suppresses Neuro-Inflammatory Cascade in Experimental Model of Diabetic Neuropathy.
Neuralgia
Synthesis, ??, ??-receptors binding affinity and antiproliferative action of new C1-substituted adamantanes.
Neuralgia
Tocotrienol attenuates oxidative-nitrosative stress and inflammatory cascade in experimental model of diabetic neuropathy.
Neurilemmoma
4'-iodo-4'-deoxydoxorubicin and tetracyclines disrupt transthyretin amyloid fibrils in vitro producing noncytotoxic species: screening for TTR fibril disrupters.
Neurilemmoma
Deposition of transthyretin in early stages of familial amyloidotic polyneuropathy: evidence for toxicity of nonfibrillar aggregates.
Neurilemmoma
Gene therapy with apoptosis-associated speck-like protein (ASC), a newly described schwannoma tumor suppressor, inhibits schwannoma growth in vivo.
Neurilemmoma
Oxidized low-density lipoprotein (oxLDL) induces cell death in neuroblastoma and survival autophagy in schwannoma cells.
Neuroblastoma
1,2-bis(2-aminophenoxy)ethane-N,N,N'N'-tetraacetic acid (BAPTA-AM) inhibits caffeine-induced apoptosis in human neuroblastoma cells.
Neuroblastoma
1-Methyl-4-phenylpyridinium (MPP+)-induced apoptosis and mitochondrial oxidant generation: role of transferrin-receptor-dependent iron and hydrogen peroxide.
Neuroblastoma
1-trichloromethyl-1,2,3,4-tetrahydro-beta-carboline (TaClo) induces apoptosis in human neuroblastoma cell lines.
Neuroblastoma
1-trichloromethyl-1,2,3,4-tetrahydro-beta-carboline-induced apoptosis in the human neuroblastoma cell line SK-N-SH.
Neuroblastoma
10-Hydroxycamptothecin induces apoptosis in human neuroblastoma SMS-KCNR cells through p53, cytochrome c and caspase 3 pathways.
Neuroblastoma
5'-aminoimidazole-4-carboxamide riboside induces apoptosis in human neuroblastoma cells.
Neuroblastoma
A highly bioactive lignophenol derivative from bamboo lignin exhibits a potent activity to suppress apoptosis induced by oxidative stress in human neuroblastoma SH-SY5Y cells.
Neuroblastoma
A novel evidence of different mechanisms of lithium and valproate neuroprotective action on human SY5Y neuroblastoma cells: caspase-3 dependency.
Neuroblastoma
Activated double-stranded RNA-dependent protein kinase and neuronal death in models of Alzheimer's disease.
Neuroblastoma
Activation of caspase-3 alone is insufficient for apoptotic morphological changes in human neuroblastoma cells.
Neuroblastoma
Active c-jun N-terminal kinase induces caspase cleavage of tau and additional phosphorylation by GSK-3beta is required for tau aggregation.
Neuroblastoma
Activin receptor signaling regulates prostatic epithelial cell adhesion and viability.
Neuroblastoma
Acute exposure to lead acetate activates microglia and induces subsequent bystander neuronal death via caspase-3 activation.
Neuroblastoma
Amyloid ?1-42 (A?1-42) Induces the CDK2-Mediated Phosphorylation of Tau through the Activation of the mTORC1 Signaling Pathway While Promoting Neuronal Cell Death.
Neuroblastoma
Anti-cancer effects of thymoquinone in mouse neuroblastoma (Neuro-2a) cells through caspase-3 activation with down-regulation of XIAP.
Neuroblastoma
Antioxidant and Neuroprotective Potential of the Brown Seaweed Bifurcaria bifurcata in an in vitro Parkinson's Disease Model.
Neuroblastoma
Antioxidant effect of acetyl-l-carnitine against cisplatin-induced cardiotoxicity.
Neuroblastoma
Apoptosis in favourable neuroblastomas is not dependent on Fas (CD95/APO-1) expression but on activated caspase 3 (CPP32).
Neuroblastoma
Apoptosis induced by endoplasmic reticulum stress depends on activation of caspase-3 via caspase-12.
Neuroblastoma
Apoptotic signaling in dopamine-induced cell death: the role of oxidative stress, p38 mitogen-activated protein kinase, cytochrome c and caspases.
Neuroblastoma
Arsenic trioxide induces apoptosis in neuroblastoma cell lines through the activation of caspase 3 in vitro.
Neuroblastoma
Bcl-x L blocks mitochondrial multiple conductance channel activation and inhibits 6-OHDA-induced death in SH-SY5Y cells.
Neuroblastoma
Ca(2+)-independent caspase-3 but not Ca(2+)-dependent caspase-2 activation induced by oxidative stress leads to SH-SY5Y human neuroblastoma cell apoptosis.
Neuroblastoma
Calcium/calmodulin-dependent protein kinase IV is cleaved by caspase-3 and calpain in SH-SY5Y human neuroblastoma cells undergoing apoptosis.
Neuroblastoma
Caspase-3 activation induced by inhibition of mitochondrial complex I is facilitated by glycogen synthase kinase-3beta and attenuated by lithium.
Neuroblastoma
Caspase-3 and survivin expression in pediatric neuroblastoma and their roles in apoptosis.
Neuroblastoma
CdSe quantum dots induce apoptosis in human neuroblastoma cells via mitochondrial-dependent pathways and inhibition of survival signals.
Neuroblastoma
Cell death in amyotrophic lateral sclerosis: interplay between neuronal and glial cells.
Neuroblastoma
Ceramide Sphingolipid Signaling Mediates Tumor Necrosis Factor (TNF)-Dependent Toxicity via Caspase Signaling in Dopaminergic Neurons.
Neuroblastoma
Characterization of Chikungunya virus infection in human neuroblastoma SH-SY5Y cells: role of apoptosis in neuronal cell death.
Neuroblastoma
Characterization of phenothiazine-induced apoptosis in neuroblastoma and glioma cell lines: clinical relevance and possible application for brain-derived tumors.
Neuroblastoma
Chronic Treatment with Anesthetic Propofol Improves Cognitive Function and Attenuates Caspase Activation in Both Aged and Alzheimer's Disease Transgenic Mice.
Neuroblastoma
Chrysanthemum morifolium Ramat (CM) extract protects human neuroblastoma SH-SY5Y cells against MPP(+)-induced cytotoxicity.
Neuroblastoma
Citicoline increases glutathione redox ratio and reduces caspase-3 activation and cell death in staurosporine-treated SH-SY5Y human neuroblastoma cells.
Neuroblastoma
Cordycepin induces apoptosis and autophagy in human neuroblastoma SK-N-SH and BE(2)-M17 cells.
Neuroblastoma
CRISPR/Cas9 nickase mediated targeting of urokinase receptor gene inhibits neuroblastoma cell proliferation.
Neuroblastoma
Cryptic amyloidogenic elements in mutant NEFH causing Charcot-Marie-Tooth 2 trigger aggresome formation and neuronal death.
Neuroblastoma
Curcumin inhibits oxidative stress-induced TRPM2 channel activation, calcium ion entry and apoptosis values in SH-SY5Y neuroblastoma cells: Involvement of transfection procedure.
Neuroblastoma
Cytoprotective effects of phenolic acids on methylglyoxal-induced apoptosis in Neuro-2A cells.
Neuroblastoma
Degradation of the type I inositol 1,4,5-trisphosphate receptor by caspase-3 in SH-SY5Y neuroblastoma cells undergoing apoptosis.
Neuroblastoma
Different mechanisms of NMDA-mediated protection against neuronal apoptosis: a stimuli-dependent effect.
Neuroblastoma
Differential induction of apoptosis by antidepressants in glioma and neuroblastoma cell lines: evidence for p-c-Jun, cytochrome c, and caspase-3 involvement.
Neuroblastoma
DNA binding studies of novel Copper(II) complexes containing L-tryptophan as chiral auxiliary: in vitro antitumor activity of Cu-Sn2 complex in human neuroblastoma cells.
Neuroblastoma
DNA damage induces cdk2 protein levels and histone H2B phosphorylation in SH-SY5Y neuroblastoma cells.
Neuroblastoma
Effects of the Fas/Fas-L pathway on fluoride-induced apoptosis in SH-SY5Y cells.
Neuroblastoma
Enteric glial cells protect neurons from oxidative stress in part via reduced glutathione.
Neuroblastoma
Enzymatic Spermine Metabolites Induce Apoptosis Associated with Increase of p53, caspase-3 and miR-34a in Both Neuroblastoma Cells, SJNKP and the N-Myc-Amplified Form IMR5.
Neuroblastoma
Expression of short-form caspase 8 correlates with decreased sensitivity to Fas-mediated apoptosis in neuroblastoma cells.
Neuroblastoma
Ginsenoside Re protects methamphetamine-induced mitochondrial burdens and proapoptosis via genetic inhibition of protein kinase C ? in human neuroblastoma dopaminergic SH-SY5Y cell lines.
Neuroblastoma
Glia maturation factor overexpression in neuroblastoma cells activates glycogen synthase kinase-3beta and caspase-3.
Neuroblastoma
GSK3 promotes arsenite-induced apoptosis via facilitation of mitochondria disruption.
Neuroblastoma
Heterocyclic thioureylenes protect from calcium-dependent neuronal cell death.
Neuroblastoma
High levels of expression and nuclear localization of interleukin-1 beta converting enzyme (ICE) and CPP32 in favorable human neuroblastomas.
Neuroblastoma
Histone deacetylase 4 promotes ubiquitin-dependent proteasomal degradation of Sp3 in SH-SY5Y cells treated with di(2-ethylhexyl)phthalate (DEHP), determining neuronal death.
Neuroblastoma
HRD1 Levels Increased by Zonisamide Prevented Cell Death and Caspase-3 Activation Caused by Endoplasmic Reticulum Stress in SH-SY5Y Cells.
Neuroblastoma
Hypoxia Affects Neprilysin Expression Through Caspase Activation and an APP Intracellular Domain-dependent Mechanism.
Neuroblastoma
Identification of genes associated with paraquat-induced toxicity in SH-SY5Y cells by PCR array focused on apoptotic pathways.
Neuroblastoma
IGF-I receptor activation and BCL-2 overexpression prevent early apoptotic events in human neuroblastoma.
Neuroblastoma
In Vitro Anti-Neuroblastoma Activity of Thymoquinone Against Neuro-2a Cells via Cell-cycle Arrest.
Neuroblastoma
Increased p53 levels without caspase-3 activity and change of cell viability in 6-hydroxydopamine-treated CV1-P cells.
Neuroblastoma
Induction of apoptotic cell death by mycelium extracts of Phellinus linteus in human neuroblastoma cells.
Neuroblastoma
Infected cell protein 0 encoded by bovine herpesvirus 1 can activate caspase 3 when overexpressed in transfected cells.
Neuroblastoma
Inhibition of DNA Repair Protein Ku70 in High-Glucose Environment Aggravates the Neurotoxicity Induced by Bupivacaine in SH-SY5Y Cells.
Neuroblastoma
Inhibition of gamma ray-induced apoptosis by stimulatory heterotrimeric GTP binding protein involves Bcl-xL down-regulation in SH-SY5Y human neuroblastoma cells.
Neuroblastoma
Inhibition of glycogen synthase kinase-3 protects cells from intrinsic but not extrinsic oxidative stress.
Neuroblastoma
Insulin receptor substrate-1 and -2 mediate resistance to glucose-induced caspase-3 activation in human neuroblastoma cells.
Neuroblastoma
Insulin-like growth factor I is the key growth factor in serum that protects neuroblastoma cells from hyperosmotic-induced apoptosis.
Neuroblastoma
Interleukin 1alpha and interleukin 6 protect human neuronal SH-SY5Y cells from oxidative damage.
Neuroblastoma
Involvement of hemeoxygenase-1 in di(2-ethylhexyl) phthalate (DEHP)-induced apoptosis of Neuro-2a cells.
Neuroblastoma
Isobavachalcone, a chalcone constituent of Angelica keiskei, induces apoptosis in neuroblastoma.
Neuroblastoma
Japanese encephalitis virus infection activates caspase-8 and -9 in a FADD-independent and mitochondrion-dependent manner.
Neuroblastoma
JNK-dependent phosphorylation of c-Jun on serine 63 mediates nitric oxide-induced apoptosis of neuroblastoma cells.
Neuroblastoma
Lig-8, a highly bioactive lignophenol derivative from bamboo lignin, exhibits multifaceted neuroprotective activity.
Neuroblastoma
Mangiferin prevents the impairment of mitochondrial dynamics and an increase in oxidative stress caused by excessive fluoride in SH-SY5Y cells.
Neuroblastoma
Molecular predictors of human nervous system cancer responsiveness to enediyne chemotherapy.
Neuroblastoma
Molecular Regulations Induced by Acrolein in Neuroblastoma SK-N-SH Cells: Relevance to Alzheimer's Disease.
Neuroblastoma
Molecular regulations induced by acrolein in neuroblastoma SK-N-SH cells: relevance to Alzheimer's disease.
Neuroblastoma
mTOR/p70S6k signalling alteration by Abeta exposure as well as in APP-PS1 transgenic models and in patients with Alzheimer's disease.
Neuroblastoma
Muscarinic receptor activation protects cells from apoptotic effects of DNA damage, oxidative stress, and mitochondrial inhibition.
Neuroblastoma
Neuroblastoma chemotherapy can be augmented by immunotargeting O-acetyl-GD2 tumor-associated ganglioside.
Neuroblastoma
Neuroprotective effects of phloretin and its glycosylated derivative on rotenone-induced toxicity in human SH-SY5Y neuronal-like cells.
Neuroblastoma
Neuroprotective Effects of Selected Microbial-Derived Phenolic Metabolites and Aroma Compounds from Wine in Human SH-SY5Y Neuroblastoma Cells and Their Putative Mechanisms of Action.
Neuroblastoma
Neurorescue Activity, APP Regulation and Amyloid-beta Peptide Reduction by Novel Multi-Functional Brain Permeable Iron- Chelating- Antioxidants, M-30 and Green Tea Polyphenol, EGCG.
Neuroblastoma
Nordihydroguaiaretic acid inhibits insulin-like growth factor signaling, growth, and survival in human neuroblastoma cells.
Neuroblastoma
Novel action of epidermal growth factor on caspase 3 and its potential as a chemotherapeutic adjunct for neuroblastoma.
Neuroblastoma
Oncolytic adenovirus-mediated short hairpin RNA targeting MYCN gene induces apoptosis by upregulating RKIP in neuroblastoma.
Neuroblastoma
Overexpression of tau leads to the stimulation of neurite outgrowth, the activation of caspase 3 activity, and accumulation and phosphorylation of tau in neuroblastoma cells on cAMP treatment.
Neuroblastoma
PEST-containing nuclear protein mediates the proliferation, migration, and invasion of human neuroblastoma cells through MAPK and PI3K/AKT/mTOR signaling pathways.
Neuroblastoma
Phosphorylated c-MYC expression in Alzheimer disease, Pick's disease, progressive supranuclear palsy and corticobasal degeneration.
Neuroblastoma
PKA Inhibitor H89 (N-[2-p-bromocinnamylamino-ethyl]-5-isoquinolinesulfonamide) Attenuates Synaptic Dysfunction and Neuronal Cell Death following Ischemic Injury.
Neuroblastoma
Protection against 1-methyl-4-phenylpyridinium ion (MPP(+))-induced apoptosis by water extract of ginseng (Panax ginseng C.A. Meyer) in SH-SY5Y cells.
Neuroblastoma
Protective effect of Acanthopanax senticosus against ethanol-induced apoptosis of human neuroblastoma cell line SK-N-MC.
Neuroblastoma
Protective effect of Hypericum perforatum Linn (St. John's wort) against hydrogen peroxide-induced apoptosis on human neuroblastoma cells.
Neuroblastoma
Protective effect of L-deprenyl against apoptosis induced by okadaic acid in cultured neuronal cells.
Neuroblastoma
Protective effects of the antiparkinsonian drugs talipexole and pramipexole against 1-methyl-4-phenylpyridinium-induced apoptotic death in human neuroblastoma SH-SY5Y cells.
Neuroblastoma
Pyrido[2',1':2,3]imidazo[4,5-c]isoquinolin-5-amines as Potential Cytotoxic Agents against Human Neuroblastoma.
Neuroblastoma
Quercetin protects neuroblastoma SH-SY5Y cells against oxidative stress by inhibiting expression of Krüppel-like factor 4.
Neuroblastoma
Reovirus-induced neuronal apoptosis is mediated by caspase 3 and is associated with the activation of death receptors.
Neuroblastoma
Rosuvastatin reduces caspase-3 activity and up-regulates alpha-secretase in human neuroblastoma SH-SY5Y cells exposed to A beta.
Neuroblastoma
SapC-DOPS nanovesicles induce Smac- and Bax-dependent apoptosis through mitochondrial activation in neuroblastomas.
Neuroblastoma
Size and morphology of toxic oligomers of amyloidogenic proteins: a case study of human stefin B.
Neuroblastoma
Sodium valproate potentiates staurosporine-induced apoptosis in neuroblastoma cells via Akt/survivin independently of HDAC inhibition.
Neuroblastoma
Sparstolonin B, a novel plant derived compound, arrests cell cycle and induces apoptosis in N-myc amplified and N-myc nonamplified neuroblastoma cells.
Neuroblastoma
Stable cell lines expressing high levels of the herpes simplex virus type 1 LAT are refractory to caspase 3 activation and DNA laddering following cold shock induced apoptosis.
Neuroblastoma
Staurosporine- and H-7-induced cell death in SH-SY5Y neuroblastoma cells is associated with caspase-2 and caspase-3 activation, but not with activation of the FAS/FAS-L-caspase-8 signaling pathway.
Neuroblastoma
Structural analysis of disease-related TDP-43 D169G mutation: linking enhanced stability and caspase cleavage efficiency to protein accumulation.
Neuroblastoma
Suppressive effect of nobiletin, a citrus polymethoxyflavonoid that downregulates thioredoxin-interacting protein expression, on tunicamycin-induced apoptosis in SK-N-SH human neuroblastoma cells.
Neuroblastoma
Targeting aberrant PI3K/Akt activation by PI103 restores sensitivity to TRAIL-induced apoptosis in neuroblastoma.
Neuroblastoma
Testing the therapeutic potential of doxycycline in a Drosophila melanogaster model of Alzheimer disease.
Neuroblastoma
The mechanisms of oxidative DNA damage and apoptosis induced by norsalsolinol, an endogenous tetrahydroisoquinoline derivative associated with Parkinson's disease.
Neuroblastoma
The novel anti-neuroblastoma agent PF403, inhibits proliferation and invasion in vitro and in brain xenografts.
Neuroblastoma
The P2X7 receptor sustains the growth of human neuroblastoma cells through a substance P-dependent mechanism.
Neuroblastoma
The Pivotal Role of Ca(2+) Homeostasis in PBDE-47-Induced Neuronal Apoptosis.
Neuroblastoma
The regulation of apoptosis by the downstream regulatory element antagonistic modulator/potassium channel interacting Protein 3 (DREAM/KChIP3) through interactions with hexokinase I.
Neuroblastoma
The use of L-serine to prevent ?-methylamino-L-alanine (BMAA)-induced proteotoxic stress in vitro.
Neuroblastoma
Therapeutic targets and potential of the novel brain- permeable multifunctional iron chelator-monoamine oxidase inhibitor drug, M-30, for the treatment of Alzheimer's disease.
Neuroblastoma
TNF-? contributes to caspase-3 independent apoptosis in neuroblastoma cells: role of NFAT.
Neuroblastoma
TRAIL resistance in human neuroblastoma SK-N-AS cells is dependent on protein kinase C and involves inhibition of caspase-3 proteolytic processing.
Neuroblastoma
Xanthoangelol, a major chalcone constituent of Angelica keiskei, induces apoptosis in neuroblastoma and leukemia cells.
Neuroblastoma
[Exogenous antizyme 1 gene transfection inhibits proliferation and promotes apoptosis of human neuroblastoma SH-SY5Y cells in vitro]
Neuroblastoma
[Inhibition of tissue factor by siRNA enhances doxorubicin-induced apoptosis in human neuroblastoma]
Neurodegenerative Diseases
Actinomycetes for marine drug discovery isolated from mangrove soils and plants in China.
Neurodegenerative Diseases
Apoptotic proteins in the temporal cortex in schizophrenia: high Bax/Bcl-2 ratio without caspase-3 activation.
Neurodegenerative Diseases
Herpes Simplex Virus Type 1 Neuronal Infection Elicits Cellular and Molecular Mechanisms of Neuroinflammation and Neurodegeneration in in vitro and in vivo Mice Models.
Neurodegenerative Diseases
Identification of potent caspase-3 inhibitors for treatment of multi- neurodegenerative diseases using pharmacophore modeling and docking approaches.
Neurodegenerative Diseases
Implication of Caspase-3 as a Common Therapeutic Target for Multineurodegenerative Disorders and Its Inhibition Using Nonpeptidyl Natural Compounds.
Neurodegenerative Diseases
Inhibition of calpain and caspase-3 prevented apoptosis and preserved electrophysiological properties of voltage-gated and ligand-gated ion channels in rat primary cortical neurons exposed to glutamate.
Neurodegenerative Diseases
Label-Free and Homogenous Detection of Caspase-3-Like Proteases by Disrupting Homodimerization-Directed Bipartite Tetracysteine Display.
Neurodegenerative Diseases
Large-scale preparation of active caspase-3 in E. coli by designing its thrombin-activatable precursors.
Neurodegenerative Diseases
Memantine Can Reduce Ethanol-Induced Caspase-3 Activity and Apoptosis in H4 Cells by Decreasing Intracellular Calcium.
Neurodegenerative Diseases
Neuronally Enriched RUFY3 Is Required for Caspase-Mediated Axon Degeneration.
Neurodegenerative Diseases
Neuroprotective effects of echinacoside in the mouse MPTP model of Parkinson's disease.
Neurodegenerative Diseases
Neuroprotective effects of MAPK/ERK1/2 and calpain inhibitors on lactacystin-induced cell damage in primary cortical neurons.
Neurodegenerative Diseases
Nicotinamide Inhibits Ethanol-Induced Caspase-3 and PARP-1 Over-activation and Subsequent Neurodegeneration in the Developing Mouse Cerebellum.
Neurodegenerative Diseases
Pharmacophore Modeling and Docking Studies on Some Nonpeptide-Based Caspase-3 Inhibitors.
Neurodegenerative Diseases
Prospective clinical biomarkers of caspase-mediated apoptosis associated with neuronal and neurovascular damage following stroke and other severe brain injuries: Implications for chronic neurodegeneration.
Neurodegenerative Diseases
Protective effect of Diosmin on LPS-induced apoptosis in PC12 cells and inhibition of TNF- ? expression.
Neurodegenerative Diseases
PTK2/FAK regulates UPS impairment via SQSTM1/p62 phosphorylation in TARDBP/TDP-43 proteinopathies.
Neurodegenerative Diseases
Role of Caspase-3-Mediated Apoptosis in Chronic Caspase-3-Cleaved Tau Accumulation and Blood-Brain Barrier Damage in the Corpus Callosum after Traumatic Brain Injury in Rats.
Neurodegenerative Diseases
Self-assembled complex of probe peptide -E. Coli RNA I conjugate and nano graphene oxide for apoptosis diagnosis.
Neurodegenerative Diseases
Sulforaphane-Enriched Broccoli Sprouts Pretreated by Pulsed Electric Fields Reduces Neuroinflammation and Ameliorates Scopolamine-Induced Amnesia in Mouse Brain through Its Antioxidant Ability via Nrf2-HO-1 Activation.
Neurodegenerative Diseases
Synergetic activation of p38 mitogen-activated protein kinase and caspase-3-like proteases for execution of calyculin A-induced apoptosis but not N-methyl-d-aspartate-induced necrosis in mouse cortical neurons.
Neurodegenerative Diseases
Targeted imaging of activated caspase-3 in the central nervous system by a dual functional nano-device.
Neurodegenerative Diseases
The forkhead transcription factor FOXO3a controls microglial inflammatory activation and eventual apoptotic injury through caspase 3.
Neuroectodermal Tumors, Primitive
Antiangiogenic and proapoptotic effects of dietary restriction on experimental mouse and human brain tumors.
Neuroectodermal Tumors, Primitive
Resistance to TRAIL-induced apoptosis in primitive neuroectodermal brain tumor cells correlates with a loss of caspase-8 expression.
Neuroendocrine Tumors
Effect of everolimus on the expression of Ki-67 and caspase-3 in patients with neuroendocrine tumors.
Neurofibroma
Evaluation of Bcl-2, Bcl-x and cleaved caspase-3 in malignant peripheral nerve sheath tumors and neurofibromas.
Neurofibrosarcoma
Evaluation of Bcl-2, Bcl-x and cleaved caspase-3 in malignant peripheral nerve sheath tumors and neurofibromas.
Neuroinflammatory Diseases
Activation of GSK-3? and Caspase-3 Occurs in Nigral Dopamine Neurons during the Development of Apoptosis Activated by a Striatal Injection of 6-Hydroxydopamine.
Neuroinflammatory Diseases
Acute LPS sensitization and continuous infusion exacerbates hypoxic brain injury in a piglet model of neonatal encephalopathy.
Neuroinflammatory Diseases
Angiotensin II Receptor Blockers Attenuate Lipopolysaccharide-Induced Memory Impairment by Modulation of NF-?B-Mediated BDNF/CREB Expression and Apoptosis in Spontaneously Hypertensive Rats.
Neuroinflammatory Diseases
Annexin A1 Bioactive Peptide Promotes Resolution of Neuroinflammation in a Rat Model of Exsanguinating Cardiac Arrest Treated by Emergency Preservation and Resuscitation.
Neuroinflammatory Diseases
Anthocyanins Improve Hippocampus-Dependent Memory Function and Prevent Neurodegeneration via JNK/Akt/GSK3? Signaling in LPS-Treated Adult Mice.
Neuroinflammatory Diseases
Anti-Amnesic Effect of Walnut via the Regulation of BBB Function and Neuro-Inflammation in A?1-42-Induced Mice.
Neuroinflammatory Diseases
Apelin-13 attenuates spatial memory impairment by anti-oxidative, anti-apoptosis, and anti-inflammatory mechanism against ethanol neurotoxicity in the neonatal rat hippocampus.
Neuroinflammatory Diseases
Assessment of the Effects of MPTP and Paraquat on Dopaminergic Neurons and Microglia in the Substantia Nigra Pars Compacta of C57BL/6 Mice.
Neuroinflammatory Diseases
Avenanthramide-C Restores Impaired Plasticity and Cognition in Alzheimer's Disease Model Mice.
Neuroinflammatory Diseases
Cortisol-induced immune suppression by a blockade of lymphocyte egress in traumatic brain injury.
Neuroinflammatory Diseases
Cyclooxygenase (COX)-1 Activity Precedes the COX-2 Induction in Abeta-Induced Neuroinflammation.
Neuroinflammatory Diseases
Dysfunctional cerebrovascular tone contributes to cognitive impairment in a non-obese rat model of prediabetic challenge: Role of suppression of autophagy and modulation by anti-diabetic drugs.
Neuroinflammatory Diseases
Ethanol extract of Scutellaria baicalensis Georgi prevents oxidative damage and neuroinflammation and memorial impairments in artificial senescense mice.
Neuroinflammatory Diseases
Hazelnut and neuroprotection: Improved memory and hindered anxiety in response to intra-hippocampal A? injection.
Neuroinflammatory Diseases
Increased levels of bioactive IL-16 correlate with disease activity during relapsing experimental autoimmune encephalomyelitis (EAE).
Neuroinflammatory Diseases
Inhibiting aberrant p53-PUMA feedback loop activation attenuates ischaemia reperfusion-induced neuroapoptosis and neuroinflammation in rats by downregulating caspase 3 and the NF-?B cytokine pathway.
Neuroinflammatory Diseases
Inhibition of serine palmitoyltransferase by a small organic molecule promotes neuronal survival after astrocyte amyloid beta 1-42 injury.
Neuroinflammatory Diseases
Long Non-coding RNA TUG1 Promotes Parkinson's Disease via Modulating MiR-152-3p/PTEN Pathway.
Neuroinflammatory Diseases
Lycopene attenuates aluminum-induced hippocampal lesions by inhibiting oxidative stress-mediated inflammation and apoptosis in the rat.
Neuroinflammatory Diseases
MicroRNA-125b mimic inhibits ischemia reperfusion-induced neuroinflammation and aberrant p53 apoptotic signalling activation through targeting TP53INP1.
Neuroinflammatory Diseases
MicroRNA-206 relieves irradiation-induced neuroinflammation by regulating connexin 43.
Neuroinflammatory Diseases
Neuroprotective effects of hydrogen inhalation in an experimental rat intracerebral hemorrhage model.
Neuroinflammatory Diseases
Neuroprotective Potential of Berberine Against Doxorubicin-Induced Toxicity in Rat's Brain.
Neuroinflammatory Diseases
Nicotine-Induced Neuroprotection against Cognitive Dysfunction after Partial Hepatectomy Involves Activation of BDNF/TrkB Signaling Pathway and Inhibition of NF-?B Signaling Pathway in Aged Rats.
Neuroinflammatory Diseases
Pharmacological doses of melatonin impede cognitive decline in tau-related Alzheimer models, once tauopathy is initiated, by restoring the autophagic flux.
Neuroinflammatory Diseases
Protective Effects of 1-Methylnicotinamide on A?1-42-Induced Cognitive Deficits, Neuroinflammation and Apoptosis in Mice.
Neuroinflammatory Diseases
SIRT1 Mediates Apelin-13 in Ameliorating Chronic Normobaric Hypoxia-induced Anxiety-like Behavior by Suppressing NF-?B Pathway in Mice Hippocampus.
Neuroinflammatory Diseases
Spinal caspase-3 contributes to tibial fracture-associated postoperative allodynia via up-regulation of LRRTM1 expression in mice.
Neuroinflammatory Diseases
Tachykinin NK1 receptor antagonist L-733,060 and substance P deletion exert neuroprotection through inhibiting oxidative stress and cell death after traumatic brain injury in mice.
Neuroinflammatory Diseases
TNFR1-JNK signaling is the shared pathway of neuroinflammation and neurovascular damage after LPS-sensitized hypoxic-ischemic injury in the immature brain.
Neuroinflammatory Diseases
Tualang Honey Reduced Neuroinflammation and Caspase-3 Activity in Rat Brain after Kainic Acid-Induced Status Epilepticus.
Neuroinflammatory Diseases
Uric Acid Neuroprotection Associated to IL-6/STAT3 Signaling Pathway Activation in Rat Ischemic Stroke.
Neurologic Manifestations
Activation of autophagy improved the neurologic outcome after cardiopulmonary resuscitation in rats.
Neurologic Manifestations
Effect of Sargentodoxa cuneata total phenolic acids on focal cerebral ischemia reperfusion injury rats model.
Neurologic Manifestations
Effects of heme oxygenase 1 on brain edema and neurologic outcome after cardiopulmonary resuscitation in rats.
Neurologic Manifestations
Hypothermia-induced neuroprotection is associated with reduced mitochondrial membrane permeability in a swine model of cardiac arrest.
Neurologic Manifestations
Inhibition of apoptosis by hyperbaric oxygen in a rat focal cerebral ischemic model.
Neurologic Manifestations
Neuroprotective effect of ginkgetin in experimental cerebral ischemia/reperfusion via apoptosis inhibition and PI3K/Akt/mTOR signaling pathway activation.
Neurologic Manifestations
Neuroprotective effects of hydrogen inhalation in an experimental rat intracerebral hemorrhage model.
Neurologic Manifestations
PD98059 Protects Brain against Cells Death Resulting from ROS/ERK Activation in a Cardiac Arrest Rat Model.
Neurologic Manifestations
Trans-activator of transcription-mediated delivery of NEP1-40 protein into brain has a neuroprotective effect against focal cerebral ischemic injury via inhibition of neuronal apoptosis.
Neutropenia
G-CSF improves murine G6PC3-deficient neutrophil function by modulating apoptosis and energy homeostasis.
Newcastle Disease
Biochemical Variations in Cytolytic Activity of Ortho- and Paramyxoviruses in Human Lung Tumor Cell Culture.
Non-alcoholic Fatty Liver Disease
Apoptosis markers in liver biopsy of nonalcoholic steatohepatitis in pediatric patients.
Non-alcoholic Fatty Liver Disease
Autophagy in ovary and polycystic ovary syndrome: role, dispute and future perspective.
Non-alcoholic Fatty Liver Disease
Caspase 3, 6, 8, and 9 Gene Expression in Peripheral Blood Leukocytes and Plasma Concentrations of IL-6 and TNF-? in Carriers of Different Polymorphic Marker -174G>C Genotypes of IL6 Gene Associated with the Risk of Nonalcoholic Steatohepatitis.
Non-alcoholic Fatty Liver Disease
Foxp3 expression in liver correlates with the degree but not the cause of inflammation.
Non-alcoholic Fatty Liver Disease
Garlic-Derived S-Allylmercaptocysteine Ameliorates Nonalcoholic Fatty Liver Disease in a Rat Model through Inhibition of Apoptosis and Enhancing Autophagy.
Non-alcoholic Fatty Liver Disease
High-fat diet decreases activity of the oxidative phosphorylation complexes and causes nonalcoholic steatohepatitis in mice.
Non-alcoholic Fatty Liver Disease
Is alanine aminotransferase level a surrogate biomarker of hepatic apoptosis in nonalcoholic fatty liver disease?
Non-alcoholic Fatty Liver Disease
Network pharmacology analysis of Chaihu Lizhong Tang treating non-alcoholic fatty liver disease.
Non-alcoholic Fatty Liver Disease
Network Pharmacology-Based Investigation of the Therapeutic Mechanisms of Action of Danning Tablets in Nonalcoholic Fatty Liver Disease.
Non-alcoholic Fatty Liver Disease
PPAR ? inhibition protects against palmitic acid-LPS induced lipidosis and injury in cultured hepatocyte L02 cell.
Non-alcoholic Fatty Liver Disease
Ziziphus spina-christi (L.) fortified with Camellia sinensis mediates apoptosis, Notch-1 signaling, and mitigates obesity-induced non-alcoholic fatty liver.
Non-alcoholic Fatty Liver Disease
[Effects of three Wenyang Jianpi Tang on cell proliferation and apoptosis of nonalcoholic fatty liver cells].
Non-alcoholic Fatty Liver Disease
[Intervention of Catalpol on High-fat Diet Induced Nonalcoholic Fatty Liver Disease in Mice].
Non-alcoholic Fatty Liver Disease
[Pathogenesis and treatment of non-alcoholic fatty liver disease.]
non-specific serine/threonine protein kinase deficiency
ROCK1 Deficiency Enhances Protective Effects of Antioxidants against Apoptosis and Cell Detachment.
Obesity
Early Morphological and Functional Reorganization of the Articular Cartilage in Rats with Experimental Osteoarthrosis of Different Genesis.
Obesity
Effect of obesity reduction on preservation of heart function and attenuation of left ventricular remodeling, oxidative stress and inflammation in obese mice.
Obesity
Estrogen inhibits the effects of obesity and alcohol on mammary tumors and fatty liver.
Obesity
High-fat diet feeding causes rapid, non-apoptotic cleavage of caspase-3 in astrocytes.
Obesity
Maternal obesity in mice not only affects fresh embryo quality but also aggravates injury due to vitrification.
Obesity
Protective Effect of Gymnema sylvestre Ethanol Extract on High Fat Diet-induced Obese Diabetic Wistar Rats.
Obesity
The coexistence of nocturnal sustained hypoxia and obesity additively increases cardiac apoptosis.
Obesity
The effect of high fat diet-induced obesity on cardiovascular toxicity in wistar albino rats.
Obesity
The effect of metformin on biomarkers and survivals for breast cancer- a systematic review and meta-analysis of randomized clinical trials.
Obstetric Labor, Premature
Preconditioning the uterine unfolded protein response maintains non-apoptotic Caspase 3-dependent quiescence during pregnancy.
Ocular Hypertension
Alpha B-crystallin improved survival of retinal ganglion cells in a rat model of acute ocular hypertension.
Ocular Hypertension
Caspase activation and amyloid precursor protein cleavage in rat ocular hypertension.
Ocular Hypertension
The effects of intravitreal H2 S application on apoptosis in the retina and cornea in experimental glaucoma model.
Odontogenic Cysts
Botryoid odontogenic cyst. Exploration of proliferative activity, apoptosis and expression of TP53 and BCL2 compared to the histologically identical lateral periodontal and gingival cysts.
Odontogenic Cysts
Immunohistochemical profile of the anti-apoptosis, apoptosis and proliferation markers Bcl-2, caspase-3, p53, and Ki-67 in botryoid odontogenic cysts compared to lateral periodontal cysts and gingival cysts of the adult.
Odontogenic Cysts
Role of HIF-1? and CASPASE-3 in cystogenesis of odontogenic cysts and tumors.
Odontogenic Tumors
Role of HIF-1? and CASPASE-3 in cystogenesis of odontogenic cysts and tumors.
Oligodendroglioma
DNA replication licensing and cell cycle kinetics of oligodendroglial tumours.
Oligospermia
Caspase-3 detection in human testicular spermatozoa from azoospermic and non-azoospermic patients.
Oligospermia
Long-term apoptotic cell death process with increased expression and activation of caspase-3 and -6 in adult rat germ cells exposed in utero to flutamide.
Olivopontocerebellar Atrophies
Cell death signaling in the cerebellum in Creutzfeldt-Jakob disease.
Ophthalmoplegia, Chronic Progressive External
Apoptosis is suspended in muscle of mitochondrial encephalomyopathies.
Ophthalmoplegia, Chronic Progressive External
[Expressions of PDCD5 and other apoptosis-related proteins in muscle of patients with mitochondrial cytopathy]
Optic Atrophy, Autosomal Dominant
A negative electroretinogram (ERG) in a case of probable multiple system atrophy (MSA).
Optic Atrophy, Autosomal Dominant
Arsenic-induced cardiotoxicity correlates with mitochondrial damage and trace elements imbalance in broiler chickens.
Optic Atrophy, Hereditary, Leber
A negative electroretinogram (ERG) in a case of probable multiple system atrophy (MSA).
Optic Nerve Diseases
A negative electroretinogram (ERG) in a case of probable multiple system atrophy (MSA).
Optic Nerve Diseases
Proteomics analyses of human optic nerve head astrocytes following biomechanical strain.
Optic Nerve Injuries
Apoptotic Retinal Ganglion Cell Death After Optic Nerve Transection or Crush in Mice: Delayed RGC Loss With BDNF or a Caspase 3 Inhibitor.
Optic Nerve Injuries
Caspase-3 inhibitor Z-DEVD-FMK enhances retinal ganglion cell survival and vision restoration after rabbit traumatic optic nerve injury.
Optic Nerve Injuries
Correlations of SDF-1 and CXCR4 levels with caspase-3 expression in the retina of rats after optic nerve injury.
Optic Nerve Injuries
Effect of GDNF gene transfer into axotomized retinal ganglion cells using in vivo electroporation with a contact lens-type electrode.
Optic Nerve Injuries
Low-dose carbon monoxide inhalation protects neuronal cells from apoptosis after optic nerve crush.
Optic Nerve Injuries
[Experimental study on treatment of rabbits optic nerve injury with Caspase-3 inhibitor z-DEVD-fmk].
Optic Neuropathy, Ischemic
[Acupuncture of intraorbital and extraorbital acupoints reduces apoptosis of retinal ganglion by down-regulating expression of Caspase-3 and ratio of Bax/Bcl-2 in rabbits with nonarteritis anterior ischemic optic neuropathy].
Optic Neuropathy, Ischemic
[Caspase inhibition: From cellular biology and thanatology to potential clinical agents].
Oral Submucous Fibrosis
Caspase-3 expression in normal oral epithelium, oral submucous fibrosis and oral squamous cell carcinoma.
Oropharyngeal Neoplasms
CASP8 (rs3834129) and CASP3 (rs4647601) polymorphisms in oropharynx cancer risk, tumor cell differentiation, and prognosis in a cohort of the Brazilian population.
Osteoarthritis
ATF6 upregulates XBP1S and inhibits ER stress-mediated apoptosis in osteoarthritis cartilage.
Osteoarthritis
BMP-7 protects against progression of cartilage degeneration after impact injury.
Osteoarthritis
Calcyclin (S100A6) Attenuates Inflammatory Response and Mediates Apoptosis of Chondrocytes in Osteoarthritis via the PI3K/AKT Pathway.
Osteoarthritis
COL2A1 and Caspase-3 as Promising Biomarkers for Osteoarthritis Prognosis in an Equus asinus Model.
Osteoarthritis
Combination of preconditioned adipose-derived mesenchymal stem cells and platelet-rich plasma improves the repair of osteoarthritis in rat.
Osteoarthritis
Comparing different physical factors on serum TNF-? levels, chondrocyte apoptosis, caspase-3 and caspase-8 expression in osteoarthritis of the knee in rabbits.
Osteoarthritis
Correlation of synovial caspase-3 concentration and the photodynamic effectiveness in the osteoarthritis treatment.
Osteoarthritis
Effect of Toddalia asiatica extract combined with miR-483 on proliferation, apoptosis and inflammatory factors expression of osteoarthritis chondrocyte.
Osteoarthritis
General Caspase Inhibition in Primary Chondrogenic Cultures Impacts Their Transcription Profile Including Osteoarthritis-Related Factors.
Osteoarthritis
Influence of swimming exercise on the expression of apoptotic gene caspase-3 in chondrocytes in osteoarthritis.
Osteoarthritis
Licofelone (ML-3000), a dual inhibitor of 5-lipoxygenase and cyclooxygenase, reduces the level of cartilage chondrocyte death in vivo in experimental dog osteoarthritis: inhibition of pro-apoptotic factors.
Osteoarthritis
Modulation by proinflammatory cytokines of Fas/Fas ligand-mediated apoptotic cell death of synovial cells in patients with rheumatoid arthritis (RA).
Osteoarthritis
Molecular changes indicative of cartilage degeneration and osteoarthritis development in patients with anterior cruciate ligament injury.
Osteoarthritis
MTORC1 coordinates the autophagy and apoptosis signaling in articular chondrocytes in osteoarthritic temporomandibular joint.
Osteoarthritis
Selective inhibition of inducible nitric oxide synthase reduces progression of experimental osteoarthritis in vivo: possible link with the reduction in chondrocyte apoptosis and caspase 3 level.
Osteoarthritis
Shikonin inhibits inflammation and chondrocyte apoptosis by regulation of the PI3K/Akt signaling pathway in a rat model of osteoarthritis.
Osteoarthritis
The effect of different treatment time of millimeter wave on chondrocyte apoptosis, caspase-3, caspase-8, and MMP-13 expression in rabbit surgically induced model of knee osteoarthritis.
Osteoarthritis
TNF-?/TNF-R System May Represent a Crucial Mediator of Proliferative Synovitis in Hemophilia A.
Osteoarthritis
[Correlation between expression of aquaporins 1 and chondrocyte apoptosis in articular chondrocyte of osteoarthritis].
Osteoarthritis
[Correlation of apoptosis of articular chondrocytes in osteoarthritis with degree of cartilage destruction and expression of apoptosis-related proteins: surviving, caspase-3, and Bcl-xl]
Osteoarthritis, Knee
Comparing different physical factors on serum TNF-? levels, chondrocyte apoptosis, caspase-3 and caspase-8 expression in osteoarthritis of the knee in rabbits.
Osteoarthritis, Knee
Effect of Warm Acupuncture Combined with Bone Marrow Mesenchymal Stem Cells Transplantation on Cartilage Tissue in Rabbit Knee Osteoarthritis.
Osteoarthritis, Knee
The effect of different treatment time of millimeter wave on chondrocyte apoptosis, caspase-3, caspase-8, and MMP-13 expression in rabbit surgically induced model of knee osteoarthritis.
Osteoarthritis, Knee
The effect of low-level laser to apoptosis of chondrocyte and caspases expression, including caspase-8 and caspase-3 in rabbit surgery-induced model of knee osteoarthritis.
Osteoarthritis, Knee
The effect of therapeutic ultrasound to apoptosis of chondrocyte and caspase-3 and caspase-8 expression in rabbit surgery-induced model of knee osteoarthritis.
Osteoarthritis, Knee
[Effect of HSP70 on apoptotic of cartilage cells in knee osteoarthritis].
Osteoarthritis, Knee
[Effects of inner-heating acupuncture on apoptosis of chondrocytes and expression of Caspase-3 and Caspase-9 in rats with knee osteoarthritis].
Osteolysis
[Expression of Caspase-3 and apoptosis in interface membranes of aseptically-loose total hip replacement]
Osteolysis
[Release of TNF-alpha and activation of Caspase-3 during apoptosis of human mononuclear cell induced by metal ion]
Osteolysis
[Role and mechanism of endoplasmic reticulum stress response induced by wear particles in osteolysis].
Osteonecrosis
Bisphosphonate-related osteonecrosis induced change in alveolar bone architecture in rats with participation of Wnt signaling.
Osteonecrosis
Caspase-3 may be employed as an early predictor for fracture?induced osteonecrosis of the femoral head in a canine model.
Osteonecrosis
The protective effect of PFT? on alcohol-induced osteonecrosis of the femoral head.
Osteoporosis
An Unbalanced Rearrangement of Chromosomes 4:20 is Associated with Childhood Osteoporosis and Reduced Caspase-3 Levels.
Osteoporosis
Bone-Specific Overexpression of PITX1 Induces Senile Osteoporosis in Mice Through Deficient Self-Renewal of Mesenchymal Progenitors and Wnt Pathway Inhibition.
Osteoporosis
Exploring the Pharmacological Mechanism of Duhuo Jisheng Decoction in Treating Osteoporosis Based on Network Pharmacology.
Osteoporosis
Simvastatin protects human osteosarcoma cells from oxidative stress-induced apoptosis through mitochondrial-mediated signaling.
Osteosarcoma
(9R)-9-Hydroxystearate-Functionalized Hydroxyapatite as Antiproliferative and Cytotoxic Agent toward Osteosarcoma Cells.
Osteosarcoma
5-Aminolevulinic Acid-Based Sonodynamic Therapy Induces the Apoptosis of Osteosarcoma in Mice.
Osteosarcoma
A two-compartment bone tumor model to investigate interactions between healthy and tumor cells.
Osteosarcoma
Adenovirus-mediated ING4 Gene Transfer in Osteosarcoma Suppresses Tumor Growth via Induction of Apoptosis and Inhibition of Tumor Angiogenesis.
Osteosarcoma
Aluminium blunts the proliferative response and increases apoptosis of cultured human cells: putative relationship to alzheimer's disease.
Osteosarcoma
Anticancer effects of 10-hydroxycamptothecin induce apoptosis of human osteosarcoma through activating caspase-3, p53 and cytochrome
Osteosarcoma
Apoptosis induced by chamaejasmine in human osteosarcoma cells through p53 pathway.
Osteosarcoma
Bacterial redox protein azurin induce apoptosis in human osteosarcoma U2OS cells.
Osteosarcoma
Benzyl isothiocyanate (BITC) and phenethyl isothiocyanate (PEITC)-mediated generation of reactive oxygen species causes cell cycle arrest and induces apoptosis via activation of caspase-3, mitochondria dysfunction and Nitric Oxide (NO) in human osteogenic sarcoma U-2 OS cells.
Osteosarcoma
Betulin inhibits mTOR and induces autophagy to promote apoptosis in human osteosarcoma cell lines.
Osteosarcoma
Catechins-Modified Selenium-Doped Hydroxyapatite Nanomaterials for Improved Osteosarcoma Therapy Through Generation of Reactive Oxygen Species.
Osteosarcoma
CCT128930 induces G1-phase arrest and apoptosis and synergistically enhances the anticancer efficiency of VS5584 in human osteosarcoma cells.
Osteosarcoma
ClC-5 Downregulation Induces Osteosarcoma Cell Apoptosis by Promoting Bax and tBid Complex Formation.
Osteosarcoma
Desipramine-induced Ca-independent apoptosis In Mg63 human osteosarcoma cells: dependence on P38 mitogen-activated protein kinase-regulated activation of caspase 3.
Osteosarcoma
DownRegulated SOX4 Expression Suppresses Cell Proliferation, Migration, and Induces Apoptosis in Osteosarcoma In Vitro and In Vivo.
Osteosarcoma
Downregulation of microRNA-95-3p suppresses cell growth of osteosarcoma via CDKN1A/p21 expression.
Osteosarcoma
Doxorubicin Inhibits Proliferation of Osteosarcoma Cells Through Upregulation of the Notch Signaling Pathway.
Osteosarcoma
Effect of low- and high-linear energy transfer radiation on in vitro and orthotopic in vivo models of osteosarcoma by activation of caspase-3 and -9.
Osteosarcoma
Effects of baicalein on apoptosis, cell cycle arrest, migration and invasion of osteosarcoma cells.
Osteosarcoma
Effects of SOST Gene Silencing on Proliferation, Apoptosis, Invasion, and Migration of Human Osteosarcoma Cells Through the Wnt/?-Catenin Signaling Pathway.
Osteosarcoma
Enhancement of Cisplatin-induced apoptosis and caspase 3 activation by depletion of mitochondrial DNA in a human osteosarcoma cell line.
Osteosarcoma
Epirubicin-mediated expression of miR-302b is involved in osteosarcoma apoptosis and cell cycle regulation.
Osteosarcoma
Fluoroquinolone-mediated inhibition of cell growth, s-g(2)/m cell cycle arrest, and apoptosis in canine osteosarcoma cell lines.
Osteosarcoma
Functional and biological analysis of Bcl-xL expression in human osteosarcoma.
Osteosarcoma
Ginsenoside Rg5 Inhibits Human Osteosarcoma Cell Proliferation and Induces Cell Apoptosis through PI3K/Akt/mTORC1-Related LC3 Autophagy Pathway.
Osteosarcoma
Growth inhibition and induction of apoptosis by 2-methoxyestradiol in rat osteosarcoma and malignant fibrous histiocytoma cell lines.
Osteosarcoma
Homeobox C10 knockdown suppresses cell proliferation and promotes cell apoptosis in osteosarcoma cells through regulating caspase 3.
Osteosarcoma
Icaritin suppresses the proliferation of human osteosarcoma cells in vitro by increasing apoptosis and decreasing MMP expression.
Osteosarcoma
Inhibitory effects of evodiamine on human osteosarcoma cell proliferation and apoptosis.
Osteosarcoma
Insulin-like growth factor I (IGF-I) stimulates proliferation but also increases caspase-3 activity, Annexin-V binding, and DNA-fragmentation in human MG63 osteosarcoma cells: co-activation of pro- and anti-apoptotic pathways by IGF-I.
Osteosarcoma
Involvement of PARP and poly(ADP-ribosyl)ation in the early stages of apoptosis and DNA replication.
Osteosarcoma
Isoalantolactone inhibits constitutive NF-?B activation and induces reactive oxygen species-mediated apoptosis in osteosarcoma U2OS cells through mitochondrial dysfunction.
Osteosarcoma
Licochalcone A Suppresses the Proliferation of Osteosarcoma Cells through Autophagy and ATM-Chk2 Activation.
Osteosarcoma
LncRNA SNHG20 knockdown suppresses the osteosarcoma tumorigenesis through the mitochondrial apoptosis pathway by miR-139/RUNX2 axis.
Osteosarcoma
Local delivery of sunitinib and Ce6 via redox-responsive zwitterionic hydrogels effectively prevents osteosarcoma recurrence.
Osteosarcoma
Matrine induces caspase-dependent apoptosis in human osteosarcoma cells in vitro and in vivo through the upregulation of Bax and Fas/FasL and downregulation of Bcl-2.
Osteosarcoma
Metastatic osteosarcoma induced by inactivation of Rb and p53 in the osteoblast lineage.
Osteosarcoma
METTL14 Overexpression Promotes Osteosarcoma Cell Apoptosis and Slows Tumor Progression via Caspase 3 Activation.
Osteosarcoma
MicroRNA-143 promotes apoptosis of osteosarcoma cells by caspase-3 activation via targeting Bcl-2.
Osteosarcoma
MicroRNA-34a inhibits tumor invasion and metastasis in osteosarcoma partly by effecting C-IAP2 and Bcl-2.
Osteosarcoma
MicroRNA-638 expression change in osteosarcoma patients via PLD1 and VEGF expression.
Osteosarcoma
MiR-138 Acts as a Tumor Suppressor by Targeting EZH2 and Enhances Cisplatin-Induced Apoptosis in Osteosarcoma Cells.
Osteosarcoma
miR-34 inhibits growth and promotes apoptosis of osteosarcoma in nude mice through targetly regulating TGIF2 expression.
Osteosarcoma
Mitochondrial DNA mutation and depletion increase the susceptibility of human cells to apoptosis.
Osteosarcoma
Molecular mechanisms of luteolin induced growth inhibition and apoptosis of human osteosarcoma cells.
Osteosarcoma
Overexpression of RBM10 induces osteosarcoma cell apoptosis and inhibits cell proliferation and migration.
Osteosarcoma
p21 overexpression sensitizes osteosarcoma U2OS cells to cisplatin via evoking caspase-3 and Bax/Bcl-2 cascade.
Osteosarcoma
Paclitaxel induces apoptosis via caspase-3 activation in human osteogenic sarcoma cells (U-2 OS).
Osteosarcoma
Paroxetine-induced apoptosis in human osteosarcoma cells: activation of p38 MAP kinase and caspase-3 pathways without involvement of [Ca2+]i elevation.
Osteosarcoma
Parthenolide Induces Reactive Oxygen Species-Mediated Autophagic Cell Death in Human Osteosarcoma Cells.
Osteosarcoma
PLGA-carbon nanotube conjugates for intercellular delivery of caspase-3 into osteosarcoma cells.
Osteosarcoma
Plumbagin induces apoptosis via the p53 pathway and generation of reactive oxygen species in human osteosarcoma cells.
Osteosarcoma
Recombinant Antisense C-myc Adenovirus Increase in vitro Sensitivity of Osteosarcoma MG-63 Cells to Cisplatin.
Osteosarcoma
REG ? knockdown suppresses proliferation by inducing apoptosis and cell cycle arrest in osteosarcoma.
Osteosarcoma
Regulation of DNAS1L3 endonuclease activity by poly(ADP-ribosyl)ation during etoposide-induced apoptosis. Role of poly(ADP-ribose) polymerase-1 cleavage in endonuclease activation.
Osteosarcoma
Resveratrol and diallyl disulfide enhance curcumin-induced sarcoma cell apoptosis.
Osteosarcoma
Salvianolic acid B suppresses cell proliferation and induces apoptosis in osteosarcoma through p38-mediated reactive oxygen species generation.
Osteosarcoma
Sensitization of osteosarcoma cell line SaOS-2 to chemotherapy by downregulating survivin.
Osteosarcoma
Serine/Threonine Kinase 35, a Target Gene of STAT3, Regulates the Proliferation and Apoptosis of Osteosarcoma Cells.
Osteosarcoma
Sevoflurane Inhibited Osteosarcoma Cell Proliferation And Invasion Via Targeting miR-203/WNT2B/Wnt/?-Catenin Axis.
Osteosarcoma
Silencing of hERG1 Gene Inhibits Proliferation and Invasion, and Induces Apoptosis in Human Osteosarcoma Cells by Targeting the NF-?B Pathway.
Osteosarcoma
Silencing of Kv1.5 Gene Inhibits Proliferation and Induces Apoptosis of Osteosarcoma Cells.
Osteosarcoma
Suppression of heat shock protein 70 by siRNA enhances the antitumor effects of cisplatin in cultured human osteosarcoma cells.
Osteosarcoma
Synergistic apoptotic effect of crocin and cisplatin on osteosarcoma cells via caspase induced apoptosis.
Osteosarcoma
The anti-apoptotic property of NS-398 at high dose can be mediated in part through NF-kappaB activation, hsp70 induction and a decrease in caspase-3 activity in human osteosarcoma cells.
Osteosarcoma
The effects of MEX3A knockdown on proliferation, apoptosis and migration of osteosarcoma cells.
Osteosarcoma
The Escalation of Osteosarcoma Stem Cells Apoptosis After the Co-Cultivation of Peripheral Blood Mononuclear Cells Sensitized with Mesenchymal Stem Cells Secretome and Colony Stimulating Factor-2 in vitro.
Osteosarcoma
The novel triterpenoid CDDO induces apoptosis and differentiation of human osteosarcoma cells by a caspase-8 dependent mechanism.
Osteosarcoma
Tideglusib suppresses stem-cell-like features and progression of osteosarcoma by inhibiting GSK-3?/NOTCH1 signaling.
Osteosarcoma
Triptolide induces the cell apoptosis of osteosarcoma cells through the TRAIL pathway.
Osteosarcoma
Variants of FasL and ABCC5 are predictive of outcome after chemotherapy-based treatment in osteosarcoma.
Osteosarcoma
Wireless Electrochemotherapy by Selenium-Doped Piezoelectric Biomaterials to Enhance Cancer Cell Apoptosis.
Osteosarcoma
Withaferin-A induces apoptosis in osteosarcoma U2OS cell line via generation of ROS and disruption of mitochondrial membrane potential.
Osteosarcoma
Withaferin-A Induces Apoptosis in Osteosarcoma U2OS Cell Line via Generation of ROS and Disruption of Mitochondrial Membrane Potential.
Osteosarcoma
Zinc promotes cell apoptosis via activating the Wnt-3a/?-catenin signaling pathway in osteosarcoma.
Osteosarcoma
[Effect of ursolic acid on proliferation and apoptosis of human osteosarcoma cell line U2-OS].
Osteosarcoma
[Inhibition of Combination of Icaritin and Doxorubicin on Human Osteosarcoma MG-63 Cells in vitro].
Otitis Media
TNFA deletion alters apoptosis as well as caspase 3 and 4 expression during otitis media.
Ototoxicity
(-)-Epigallocatechin-3-gallate protects against NO-induced ototoxicity through the regulation of caspase- 1, caspase-3, and NF-?B activation.
Ototoxicity
Alpha-lipoic acid protects against cisplatin-induced ototoxicity via the regulation of MAPKs and proinflammatory cytokines.
Ototoxicity
Minocycline prevents gentamicin-induced ototoxicity by inhibiting p38 MAP kinase phosphorylation and caspase 3 activation.
Ototoxicity
Role of inhibitor of apoptosis protein in gentamicin-induced cochlear hair cell damage.
Ototoxicity
The beneficial effect of Hangesha-shin-to (TJ-014) in gentamicin-induced hair cell loss in the rat cochlea.
Ototoxicity
[Effect of cisplatin on apoptosis of spiral ganglion cell and expression of caspase-3 in mouse cochlea].
Ovarian Cysts
Immunohistochemical evaluation of proliferation, apoptosis and steroidogenic enzymes in the ovary of rats with polycystic ovary.
Ovarian Neoplasms
(-)-Asarinin from the Roots of Asarum sieboldii Induces Apoptotic Cell Death via Caspase Activation in Human Ovarian Cancer Cells.
Ovarian Neoplasms
?-Elemene Effectively Suppresses the Growth and Survival of Both Platinum-sensitive and -resistant Ovarian Tumor Cells.
Ovarian Neoplasms
A Combination Therapy with Baicalein and Taxol Promotes Mitochondria-Mediated Cell Apoptosis: Involving in Akt/?-Catenin Signaling Pathway.
Ovarian Neoplasms
A novel series of di-fluorinated propanedione derivatives synergistically augment paclitaxel mediated caspase 3 activation in ovarian cancer cells.
Ovarian Neoplasms
A study of the potential anticancer activity of Mangifera zeylanica bark: Evaluation of cytotoxic and apoptotic effects of the hexane extract and bioassay-guided fractionation to identify phytochemical constituents.
Ovarian Neoplasms
Acquired resistance to TRAIL-induced apoptosis in human ovarian cancer cells is conferred by increased turnover of mature caspase-3.
Ovarian Neoplasms
Activation of A2b adenosine receptor regulates ovarian cancer cell growth: involvement of Bax/Bcl-2 and caspase-3.
Ovarian Neoplasms
Adenosine induces cell cycle arrest and apoptosis via cyclinD1/Cdk4 and Bcl-2/Bax pathways in human ovarian cancer cell line OVCAR-3.
Ovarian Neoplasms
Akt activation induced by lysophosphatidic acid and sphingosine-1-phosphate requires both mitogen-activated protein kinase kinase and p38 mitogen-activated protein kinase and is cell-line specific.
Ovarian Neoplasms
Alpha2,3-sialyltransferase III knockdown sensitized ovarian cancer cells to cisplatin-induced apoptosis.
Ovarian Neoplasms
AMPH1 functions as a tumour suppressor in ovarian cancer via the inactivation of PI3K/AKT pathway.
Ovarian Neoplasms
An antimitotic and antivascular agent BPR0L075 overcomes multidrug resistance and induces mitotic catastrophe in paclitaxel-resistant ovarian cancer cells.
Ovarian Neoplasms
An essential role for Ran GTPase in epithelial ovarian cancer cell survival.
Ovarian Neoplasms
Anticancer activity of NOB1-targeted shRNA combination with TRAIL in epithelial ovarian cancer cells.
Ovarian Neoplasms
Apoptotic Cell Death Induced by Resveratrol Is Partially Mediated by the Autophagy Pathway in Human Ovarian Cancer Cells.
Ovarian Neoplasms
Aspirin inhibits growth of ovarian cancer by upregulating caspase-3 and downregulating bcl-2.
Ovarian Neoplasms
Autocatalytic caspase-3 driven by human telomerase reverse transcriptase promoter suppresses human ovarian carcinoma growth in vitro and in mice.
Ovarian Neoplasms
Autocrine production of interleukin-6 confers cisplatin and paclitaxel resistance in ovarian cancer cells.
Ovarian Neoplasms
B7-H4 is Inversely Correlated With T-Cell Infiltration in Clear Cell but Not Serous or Endometrioid Ovarian Cancer.
Ovarian Neoplasms
Berbamine suppresses cell proliferation and promotes apoptosis in ovarian cancer partially via the inhibition of Wnt/?-catenin signaling.
Ovarian Neoplasms
Butein Shows Cytotoxic Effects and Induces Apoptosis in Human Ovarian Cancer Cells.
Ovarian Neoplasms
Co-administration of perifosine with paclitaxel synergistically induces apoptosis in ovarian cancer cells: More than just AKT inhibition.
Ovarian Neoplasms
Construction of three-dimensional in vitro culture model of ovarian carcinoma and the study of its multicellular drug resistance.
Ovarian Neoplasms
Cooperation of bisphenol A and leptin in inhibition of caspase-3 expression and activity in OVCAR-3 ovarian cancer cells.
Ovarian Neoplasms
Cordycepin induces apoptosis of human ovarian cancer cells by inhibiting CCL5-mediated Akt/NF-?B signaling pathway.
Ovarian Neoplasms
Costunolide Inhibits the Growth of OAW42-A Multidrug-Resistant Human Ovarian Cancer Cells by Activating Apoptotic and Autophagic Pathways, Production of Reactive Oxygen Species (ROS), Cleaved Caspase-3 and Cleaved Caspase-9.
Ovarian Neoplasms
Cytotoxicity of natural extract from Tegillarca granosa on ovarian cancer cells is mediated by multiple molecules.
Ovarian Neoplasms
Decreased expression of p16 in ovarian cancers represents an unfavourable prognostic factor.
Ovarian Neoplasms
Discovering simple phenylboronic acid and benzoxaborole derivatives for experimental oncology - phase cycle-specific inducers of apoptosis in A2780 ovarian cancer cells.
Ovarian Neoplasms
Drug conjugation to hyaluronan widens therapeutic indications for ovarian cancer.
Ovarian Neoplasms
Dual Targeting of Phosphoinositide 3-Kinase and Mammalian Target of Rapamycin Using NVP-BEZ235 as a Novel Therapeutic Approach in Human Ovarian Carcinoma.
Ovarian Neoplasms
E1A-mediated paclitaxel sensitization in HER-2/neu-overexpressing ovarian cancer SKOV3.ip1 through apoptosis involving the caspase-3 pathway.
Ovarian Neoplasms
Effect of Amino Acids on the Generation of Ginsenoside Rg3 Epimers by Heat Processing and the Anticancer Activities of Epimers in A2780 Human Ovarian Cancer Cells.
Ovarian Neoplasms
Effect of ginsenoside Rh-2 via activation of caspase-3 and Bcl-2-insensitive pathway in ovarian cancer cells.
Ovarian Neoplasms
Effect of Saponin from Tupistra chinensis Baker on proliferation and apoptosis of ovarian cancer cells by Wnt/?-Catenin pathway.
Ovarian Neoplasms
Effect of small interfering RNA transfection on FAK and DLC1 mRNA expression in OVCAR-3.
Ovarian Neoplasms
Effect of the WWOX gene on the regulation of the cell cycle and apoptosis in human ovarian cancer stem cells.
Ovarian Neoplasms
Effects Of Adenosine On Apoptosis Of Ovarian Cancer A2780 Cells Via ROS And Caspase Pathways.
Ovarian Neoplasms
Effects of salvianolic acid B on growth inhibition and apoptosis induction of ovarian cancer SKOV3.
Ovarian Neoplasms
Elevated cleaved caspase-3 is associated with shortened overall survival in several cancer types.
Ovarian Neoplasms
Endoplasmic reticulum stress promotes autophagy and apoptosis and reverses chemoresistance in human ovarian cancer cells.
Ovarian Neoplasms
Evaluation of the antitumor effects of c-Myc-Max heterodimerization inhibitor 100258-F4 in ovarian cancer cells.
Ovarian Neoplasms
Evaluation of the Potential Diagnostic Utility of the Determination of Selected Caspases-Markers Involved in the Regulation of Apoptosis-In Patients with Ovarian Cancer.
Ovarian Neoplasms
Evodiamine from Evodia rutaecarpa induces apoptosis via activation of JNK and PERK in human ovarian cancer cells.
Ovarian Neoplasms
Fluoxetine Induces Apoptosis in Ovarian Carcinoma Cell Line OVCAR-3 Through Reactive Oxygen Species-Dependent Activation of Nuclear Factor-kappaB.
Ovarian Neoplasms
Focal adhesion kinase silencing augments docetaxel-mediated apoptosis in ovarian cancer cells.
Ovarian Neoplasms
Folate decorated magnetite nanoparticles: Synthesis and targeted therapy against ovarian cancer.
Ovarian Neoplasms
FTY720 induces necrotic cell death and autophagy in ovarian cancer cells: A protective role of autophagy.
Ovarian Neoplasms
Galectin-9 induces apoptosis in OVCAR-3 ovarian cancer cell through mitochondrial pathway.
Ovarian Neoplasms
Gonadotropin-releasing hormone type II antagonists induce apoptotic cell death in human endometrial and ovarian cancer cells in vitro and in vivo.
Ovarian Neoplasms
Green tea polyphenol epigallocatechin-3-gallate inhibits the endothelin axis and downstream signaling pathways in ovarian carcinoma.
Ovarian Neoplasms
Growth inhibition and apoptosis inducing mechanisms of curcumin on human ovarian cancer cell line a2780.
Ovarian Neoplasms
High expression of ENPP1 in high-grade serous ovarian carcinoma predicts poor prognosis and as a molecular therapy target.
Ovarian Neoplasms
HO-3867, a STAT3 inhibitor induces apoptosis by inactivation of STAT3 activity in BRCA1-mutated ovarian cancer cells.
Ovarian Neoplasms
Human GM3 Synthase Attenuates Taxol-Triggered Apoptosis Associated with Downregulation of Caspase-3 in Ovarian Cancer Cells.
Ovarian Neoplasms
In vitro antitumor mechanism of a novel cyclin-dependent kinase inhibitor CDKI-83.
Ovarian Neoplasms
Inhibitory effects of bisphosphonates on the proliferation of human ovarian cancer cell lines and the mechanism.
Ovarian Neoplasms
Interaction between celecoxib and docetaxel or cisplatin in human cell lines of ovarian cancer and colon cancer is independent of COX-2 expression levels.
Ovarian Neoplasms
IP10-CDR3 Reduces The Viability And Induces The Apoptosis Of Ovarian Cancer Cells By Down-Regulating The Expression Of Bcl-2 And Caspase 3.
Ovarian Neoplasms
Knockdown of survivin contributes to antitumor activity in cisplatin-resistant ovarian cancer cells.
Ovarian Neoplasms
LDR reverses DDP resistance in ovarian cancer cells by affecting ERCC-1, Bcl-2, Survivin and Caspase-3 expressions.
Ovarian Neoplasms
Lysophosphatidic acid and endothelin-induced proliferation of ovarian cancer cell lines is mitigated by neutralization of granulin-epithelin precursor (GEP), a prosurvival factor for ovarian cancer.
Ovarian Neoplasms
Magnolol down-regulates HER2 gene expression, leading to inhibition of HER2-mediated metastatic potential in ovarian cancer cells.
Ovarian Neoplasms
MAPT (Tau) expression is a biomarker for an increased rate of survival in pediatric neuroblastoma.
Ovarian Neoplasms
Molecular determinants of epothilone B derivative (BMS 247550) and Apo-2L/TRAIL-induced apoptosis of human ovarian cancer cells.
Ovarian Neoplasms
Molecular profile of breast versus ovarian cancer cells in response to treatment with the anticancer drugs cisplatin, carboplatin, doxorubicin, etoposide and taxol.
Ovarian Neoplasms
New adamantane phenylalkylamines with ?-receptor binding affinity and anticancer activity, associated with putative antagonism of neuropathic pain.
Ovarian Neoplasms
Possible role of FLICE-like inhibitory protein (FLIP) in chemoresistant ovarian cancer cells in vitro.
Ovarian Neoplasms
Potentiation of paclitaxel-induced apoptosis by the novel cyclin-dependent kinase inhibitor NU6140: a possible role for survivin down-regulation.
Ovarian Neoplasms
Puncta intended: connecting the dots between autophagy and cell stress networks.
Ovarian Neoplasms
Reduced graphene oxide-silver nanoparticle nanocomposite: a potential anticancer nanotherapy.
Ovarian Neoplasms
Reduction of graphene oxide by resveratrol: a novel and simple biological method for the synthesis of an effective anticancer nanotherapeutic molecule.
Ovarian Neoplasms
Regulation of HtrA2/Omi by X-linked inhibitor of apoptosis protein in chemoresistance in human ovarian cancer cells.
Ovarian Neoplasms
Resistance to chemotherapy-induced apoptosis via decreased caspase-3 activity and overexpression of antiapoptotic proteins in ovarian cancer.
Ovarian Neoplasms
Restoration of microRNA-708 sensitizes ovarian cancer cells to cisplatin via IGF2BP1/Akt pathway.
Ovarian Neoplasms
Selective suppression of autocatalytic caspase-3 driven by two-step transcriptional amplified human telomerase reverse transcriptase promoter on ovarian carcinoma growth in vitro and in mice.
Ovarian Neoplasms
Src inhibition enhances paclitaxel cytotoxicity in ovarian cancer cells by caspase-9-independent activation of caspase-3.
Ovarian Neoplasms
Study on the mechanism of photodynamic therapy mediated by 5-aminoketovalerate in human ovarian cancer cell line.
Ovarian Neoplasms
Synergistic effects of retinoic acid and 8-Cl-cAMP on apoptosis require caspase-3 activation in human ovarian cancer cells.
Ovarian Neoplasms
Synergistic lethality of mifepristone and LY294002 in ovarian cancer cells.
Ovarian Neoplasms
Targeting granzyme B to tumor cells using a yoked human chorionic gonadotropin.
Ovarian Neoplasms
The milk-derived fusion peptide, ACFP, suppresses the growth of primary human ovarian cancer cells by regulating apoptotic gene expression and signaling pathways.
Ovarian Neoplasms
The mTORC2 Component Rictor Contributes to Cisplatin Resistance in Human Ovarian Cancer Cells.
Ovarian Neoplasms
Triptolide avoids cisplatin resistance and induces apoptosis via the reactive oxygen species/nuclear factor-?B pathway in SKOV3(PT) platinum-resistant human ovarian cancer cells.
Ovarian Neoplasms
Urea derivates of ursolic, oleanolic and maslinic acid induce apoptosis and are selective cytotoxic for several human tumor cell lines.
Ovarian Neoplasms
Variation in the kinetics of caspase-3 activation, Bcl-2 phosphorylation and apoptotic morphology in unselected human ovarian cancer cell lines as a response to docetaxel.
Ovarian Neoplasms
XIAP regulates Akt activity and caspase-3-dependent cleavage during cisplatin-induced apoptosis in human ovarian epithelial cancer cells.
Ovarian Neoplasms
ZD4054, a specific antagonist of the endothelin A receptor, inhibits tumor growth and enhances paclitaxel activity in human ovarian carcinoma in vitro and in vivo.
Ovarian Neoplasms
[Construction of autocatalytic caspase-3 and its effects of inducing apoptosis in human ovarian carcinoma]
Ovarian Neoplasms
[Construction of autocatalytic caspase-3 driven by amplified human telomerase reverse transcriptase promoter and its enhanced efficacy of inducing apoptosis in human ovarian carcinoma]
Ovarian Neoplasms
[Expression and clinical significance of Xiap and Caspase-3 protien in primary epithelia ovarian cancer].
Ovarian Neoplasms
[Inhibitory effects of curcumin on apoptosis of human ovary cancer cell line A2780 and its molecular mechanism]
Ovarian Neoplasms
[Relationship between cytochrome c-mediated caspase-3 activity and chemoresistance in cisplatin-resistant human ovarian cancer cell lines]
Ovarian Neoplasms
[Relationship between expression of apoptosis-associated proteins and caspase-3 activity in cisplatin-resistant human ovarian cancer cell line]
Ovarian Neoplasms
[Reverse of the resistance to paclitaxel of the heparin binding-epidermal growth factor-like growth factor inhibitor in ovarian cancer].
Ovarian Neoplasms
[Role of apoptosis-associated genes and caspase-3 in cisplatin-resistant human ovarian cancer cell lines]
Ovarian Neoplasms
[Synergism of antitumor effects on ovarian carcinoma using autocatalytic caspase-3 combined with flavopiridol].
Ovarian Neoplasms
[The efficacy of autocatalytic casapse-3 driven by human telomerase reverse transcriptase promoter on human ovarian carcinoma]
Overweight
Association Between Body Mass Index and Male Sperm Apoptosis and Apoptosis-Related Factors.
Overweight
IL-4 induces apoptosis in A549 lung adenocarcinoma cells: evidence for the pivotal role of 15-hydroxyeicosatetraenoic acid binding to activated peroxisome proliferator-activated receptor gamma transcription factor.
Overweight
Metabolic phenotype and adipose tissue inflammation in patients with chronic obstructive pulmonary disease.
Overweight
Stress kinases, endoplasmic reticulum stress, and Alzheimer's disease related markers in peripheral blood mononuclear cells from subjects with increased body weight.
Pancreatic Neoplasms
(-)-Epigallocatechin-3-gallate Inhibits Hsp90 Function by Impairing Hsp90 Association with Co-chaperones in Pancreatic Cancer Cell Line Mia Paca-2.
Pancreatic Neoplasms
3,5-bis(2,4-difluorobenzylidene)-4-piperidone, a novel compound that affects pancreatic cancer growth and angiogenesis.
Pancreatic Neoplasms
A cascade enzymatic reaction activatable gemcitabine prodrug with an AIE-based intracellular light-up apoptotic probe for in situ self-therapeutic monitoring.
Pancreatic Neoplasms
A pectin-like polysaccharide from Polygala tenuifolia inhibits pancreatic cancer cell growth in vitro and in vivo by inducing apoptosis and suppressing autophagy.
Pancreatic Neoplasms
A small-molecule induces apoptosis and suppresses metastasis in pancreatic cancer cells.
Pancreatic Neoplasms
Anti-proliferative and proapoptotic effects of benzyl isothiocyanate on human pancreatic cancer cells is linked to death receptor activation and RasGAP/Rac1 down-modulation.
Pancreatic Neoplasms
Anticancer effect of HOTTIP regulates human pancreatic cancer via the metabotropic glutamate receptor 1 pathway.
Pancreatic Neoplasms
Antitumor alkyl-lysophospholipid analog edelfosine induces apoptosis in pancreatic cancer by targeting endoplasmic reticulum.
Pancreatic Neoplasms
Antitumor Effect and Immune Response of Nanosecond Pulsed Electric Fields in Pancreatic Cancer.
Pancreatic Neoplasms
Apoptosis and anergy of T cell induced by pancreatic stellate cells-derived galectin-1 in pancreatic cancer.
Pancreatic Neoplasms
Bitter apricot ethanolic extract induces apoptosis through increasing expression of Bax/Bcl-2 ratio and caspase-3 in PANC-1 pancreatic cancer cells.
Pancreatic Neoplasms
BMP8B mediates the survival of pancreatic cancer cells and regulates the progression of pancreatic cancer.
Pancreatic Neoplasms
C-JUN and CPP32 (CASPASE 3) in human pancreatic cancer: relation to cell proliferation and death.
Pancreatic Neoplasms
Caspase-3 drives apoptosis in pancreatic cancer cells after treatment with gemcitabine.
Pancreatic Neoplasms
Combined administration of naringenin and hesperetin with optimal ratio maximizes the anti-cancer effect in human pancreatic cancer via down regulation of FAK and p38 signaling pathway.
Pancreatic Neoplasms
Combined inhibition of PAK7, MAP3K7 and CK2alpha kinases inhibits the growth of MiaPaCa2 pancreatic cancer cell xenografts.
Pancreatic Neoplasms
Curcumin analogues exhibit enhanced growth suppressive activity in human pancreatic cancer cells.
Pancreatic Neoplasms
Docoxahexaenoic Acid Induces Apoptosis of Pancreatic Cancer Cells by Suppressing Activation of STAT3 and NF-?B.
Pancreatic Neoplasms
Epigallocatechin-3-gallate induces mitochondrial membrane depolarization and caspase-dependent apoptosis in pancreatic cancer cells.
Pancreatic Neoplasms
FAK and IGF-IR interact to provide survival signals in human pancreatic adenocarcinoma cells.
Pancreatic Neoplasms
Fermented Extraction of Citrus unshiu Peel Inhibits Viability and Migration of Human Pancreatic Cancers.
Pancreatic Neoplasms
FR901228, a novel histone deacetylase inhibitor, induces cell cycle arrest and subsequent apoptosis in refractory human pancreatic cancer cells.
Pancreatic Neoplasms
Fragment-based drug design and identification of HJC0123, a novel orally bioavailable STAT3 inhibitor for cancer therapy.
Pancreatic Neoplasms
Gemcitabine inhibits proliferation and induces apoptosis in human pancreatic cancer PANC-1 cells.
Pancreatic Neoplasms
Grape Proanthocyanidin Inhibit Pancreatic Cancer Cell Growth In Vitro and In Vivo through Induction of Apoptosis and by Targeting the PI3K/Akt Pathway.
Pancreatic Neoplasms
Histological analysis of human pancreatic carcinoma following irreversible electroporation in a nude mouse model.
Pancreatic Neoplasms
Honokiol Suppressed Pancreatic Cancer Progression via miR-101/Mcl-1 Axis.
Pancreatic Neoplasms
IL-29 Exhibits Anti-Tumor Effect on Pan-48 Pancreatic Cancer Cells by Up-regulation of P21 and Bax.
Pancreatic Neoplasms
Inhibition of PI3K/AKT and MAPK/ERK pathways causes activation of FOXO transcription factor, leading to cell cycle arrest and apoptosis in pancreatic cancer.
Pancreatic Neoplasms
Inhibition of RIP and c-FLIP enhances TRAIL-induced apoptosis in pancreatic cancer cells.
Pancreatic Neoplasms
Light-emitting diode irradiation induces AKT/mTOR-mediated apoptosis in human pancreatic cancer cells and xenograft mouse model.
Pancreatic Neoplasms
LncRNA SNHG14 potentiates pancreatic cancer progression via modulation of annexin A2 expression by acting as a competing endogenous RNA for miR-613.
Pancreatic Neoplasms
Metformin Inhibits Gemcitabine Induced Apoptosis in Pancreatic Cancer Cell Lines.
Pancreatic Neoplasms
miR-597-5p inhibits cell growth and promotes cell apoptosis by targeting ELK1 in pancreatic cancer.
Pancreatic Neoplasms
Mitofusin2 Induces Cell Autophagy of Pancreatic Cancer through Inhibiting the PI3K/Akt/mTOR Signaling Pathway.
Pancreatic Neoplasms
MSX2 overexpression inhibits gemcitabine-induced caspase-3 activity in pancreatic cancer cells.
Pancreatic Neoplasms
Nano-chemotherapy using cationic liposome that strategically targets the cell membrane potential of pancreatic cancer cells with negative charge.
Pancreatic Neoplasms
NOSH-aspirin (NBS-1120) inhibits pancreatic cancer cell growth in a xenograft mouse model: Modulation of FoxM1, p53, NF-?B, iNOS, caspase-3 and ROS.
Pancreatic Neoplasms
Overexpression of the SMYD3 Promotes Proliferation, Migration, and Invasion of Pancreatic Cancer.
Pancreatic Neoplasms
Prevention of metastatic pancreatic cancer growth in vivo by induction of apoptosis with genistein, a naturally occurring isoflavonoid.
Pancreatic Neoplasms
Pro-survival Role of Heat Shock Factor 1 (HSF1) in the Pathogenesis of PancreatoBiliary Tumors.
Pancreatic Neoplasms
Reduced expression of caspase-8 and cleaved caspase-3 in pancreatic ductal adenocarcinoma cells.
Pancreatic Neoplasms
Rhein sensitizes human pancreatic cancer cells to EGFR inhibitors by inhibiting STAT3 pathway.
Pancreatic Neoplasms
Secondary Metabolites from Endophytic Fungus Penicillium pinophilum Induce ROS-Mediated Apoptosis through Mitochondrial Pathway in Pancreatic Cancer Cells.
Pancreatic Neoplasms
Silencing of Astrocyte elevated gene-1 (AEG-1) inhibits proliferation, migration and invasion, and promotes apoptosis in pancreatic cancer cells.
Pancreatic Neoplasms
SmacN7 enhances the sensitivity of pancreatic cancer cells to tumor necrosis factor-related apoptosis-inducing ligand or gemcitabine.
Pancreatic Neoplasms
Solanine induces mitochondria-mediated apoptosis in human pancreatic cancer cells.
Pancreatic Neoplasms
Synthesis, ??, ??-receptors binding affinity and antiproliferative action of new C1-substituted adamantanes.
Pancreatic Neoplasms
The role of STAT-3 in the induction of apoptosis in pancreatic cancer cells by benzyl isothiocyanate.
Pancreatic Neoplasms
The therapeutic targeting of the FGFR1/Src/NF-?B signaling axis inhibits pancreatic ductal adenocarcinoma stemness and oncogenicity.
Pancreatic Neoplasms
TRAIL and triptolide: an effective combination that induces apoptosis in pancreatic cancer cells.
Pancreatic Neoplasms
Treatment with near-infrared radiation promotes apoptosis in pancreatic cancer cells.
Pancreatic Neoplasms
U1 Adaptors suppress the KRAS-MYC oncogenic axis in human pancreatic cancer xenografts.
Pancreatic Neoplasms
Upregulation of ARHGAP30 attenuates pancreatic cancer progression by inactivating the ?-catenin pathway.
Pancreatic Neoplasms
Utilising network pharmacology to explore the underlying mechanism of Wumei Pill in treating pancreatic neoplasms.
Pancreatic Neoplasms
[The long coding RNA GSTM3TV2 acts an oncogene to promote chemoresistance in pancreatic cancer].
Pancreatitis
Ablation of phosphoinositide 3-kinase-gamma reduces the severity of acute pancreatitis.
Pancreatitis
Ameliorative Effects of Curcumin on Fibrinogen-Like Protein-2 Gene Expression, Some Oxido-Inflammatory and Apoptotic Markers in a Rat Model of l-Arginine-Induced Acute Pancreatitis.
Pancreatitis
Chaiqinchengqi decoction regulates necrosis-apoptosis via regulating the release of mitochondrial cytochrome c and caspase-3 in rats with acute necrotizing pancreatitis.
Pancreatitis
Deletion of toll-like receptor-4 downregulates protein kinase C-zeta and attenuates liver injury in experimental pancreatitis.
Pancreatitis
Effects of emodin on intestinal mucosal barrier by the upregulation of miR-218a-5p expression in rats with acute necrotizing pancreatitis.
Pancreatitis
Effects of Panax notoginseng saponins on severe acute pancreatitis through the regulation of mTOR/Akt and caspase-3 signaling pathway by upregulating miR-181b expression in rats.
Pancreatitis
Honokiol Attenuates the Severity of Acute Pancreatitis and Associated Lung Injury via Acceleration of Acinar Cell Apoptosis.
Pancreatitis
Influence of baicalin on TNF-alpha mRNA, caspase-3 and P-selectin expression in pancreatic tissue of rats with severe acute pancreatitis.
Pancreatitis
Liver injury during acute pancreatitis: the role of pancreatitis-associated ascitic fluid (PAAF), p38-MAPK, and caspase-3 in inducing hepatocyte apoptosis.
Pancreatitis
Protein kinase C-zeta is critical in pancreatitis-induced apoptosis of Kupffer cells.
Pancreatitis
The role of p65 NF-kappaB/RelA in pancreatitis-induced Kupffer cell apoptosis.
Pancreatitis
[Role of polymorphonuclear neutrophil apoptosis and expression of Fas and caspase-3 in the systemic inflammatory response syndrome]
Pancreatitis, Acute Necrotizing
Aquatic birnavirus induces necrotic cell death via the mitochondria-mediated caspase pathway.
Pancreatitis, Acute Necrotizing
Chaiqinchengqi decoction regulates necrosis-apoptosis via regulating the release of mitochondrial cytochrome c and caspase-3 in rats with acute necrotizing pancreatitis.
Pancreatitis, Acute Necrotizing
Cholinergic mediation of alcohol-induced experimental pancreatitis.
Pancreatitis, Chronic
Fraxetin prevented sodium fluoride-induced chronic pancreatitis in rats: Role of anti-inflammatory, antioxidant, antifibrotic and anti-apoptotic activities.
Papilloma
A synthetic coumarin (4-Methyl-7 hydroxy coumarin) has anti-cancer potentials against DMBA-induced skin cancer in mice.
Papilloma
Activation of P2X(7)-mediated apoptosis Inhibits DMBA/TPA-induced formation of skin papillomas and cancer in mice.
Papilloma
Apoptosis-related Proteins Are Altered by Selective Tyrosine Kinase Inhibitors and Everolimus in HPV-dependent SCC.
Papilloma
c-Jun N-terminal kinase 1 phosphorylates Myt1 to prevent UVA-induced skin cancer.
Papilloma
Constitutive transgene expression of Stem Cell Antigen-1 in the hair follicle alters the sensitivity to tumor formation and progression.
Papilloma
Modulation of Signal Proteins: A Plausible Mechanism to Explain How a Potentized Drug Secale Cor 30C Diluted beyond Avogadro's Limit Combats Skin Papilloma in Mice.
Papilloma
Raised expression of the antiapoptotic protein ped/pea-15 increases susceptibility to chemically induced skin tumor development.
Papilloma
The role of stem cell antigen-1/Lymphocyte antigen 6A-2/6E-1 knock out in murine epidermis.
Papilloma
UV-vulnerability of human papilloma virus type-16 E7-expressing astrocytes is associated with mitochondrial membrane depolarization and caspase-3 activation.
Papilloma
[Correlation of the expression of survivin and caspase-3 proteins in juvenile laryngeal papilloma]
Papilloma, Inverted
Down-regulation of gelsolin may play a role in the progression of inverted papilloma through an antiapoptotic mechanism.
Paralysis
Dysequilibrium between caspases and their inhibitors in a mouse model for amyotrophic lateral sclerosis.
Paralysis
Inflammation and neuronal death in the motor cortex of the wobbler mouse, an ALS animal model.
Paramyxoviridae Infections
Bta-miR-98 Suppresses Replication of Caprine Parainfluenza Virus Type 3 Through Inhibiting Apoptosis by Targeting Caspase-3.
Paraplegia
Delayed paraplegia after spinal cord ischemic injury requires caspase-3 activation in mice.
Paresis
Dexmedetomidine attenuates cerebral ischemia-reperfusion injury in rats by inhibiting the JNK pathway.
Parkinson Disease
A Novel Non-Apoptotic Role of Procaspase-3 in the Regulation of Mitochondrial Biogenesis Activators.
Parkinson Disease
A novel peptide inhibitor targeted to caspase-3 cleavage site of a proapoptotic kinase protein kinase C delta (PKCdelta) protects against dopaminergic neuronal degeneration in Parkinson's disease models.
Parkinson Disease
Acteoside Binds to Caspase-3 and Exerts Neuroprotection in the Rotenone Rat Model of Parkinson's Disease.
Parkinson Disease
Alpha-synuclein lowers p53-dependent apoptotic response of neuronal cells. Abolishment by 6-hydroxydopamine and implication for Parkinson's disease.
Parkinson Disease
Apoptosis induced by an endogenous neurotoxin, N-methyl(R)salsolinol, is mediated by activation of caspase 3.
Parkinson Disease
Association of Parkinson Disease Induction with Cardiac Upregulation of Apoptotic Mediators P53 and Active Caspase-3: An Immunohistochemistry Study.
Parkinson Disease
Beta-synuclein displays an antiapoptotic p53-dependent phenotype and protects neurons from 6-hydroxydopamine-induced caspase 3 activation: cross-talk with alpha-synuclein and implication for Parkinson's disease.
Parkinson Disease
Caspase-3: A vulnerability factor and final effector in apoptotic death of dopaminergic neurons in Parkinson's disease.
Parkinson Disease
Correction: Targeting Caspase-3 as Dual Therapeutic Benefits by RNAi Facilitating Brain-Targeted Nanoparticles in a Rat Model of Parkinson's Disease.
Parkinson Disease
Cytoprotection against Hypoxic and/or MPP? Injury: Effect of ?-Opioid Receptor Activation on Caspase 3.
Parkinson Disease
Effects of Zhichan powder on signal transduction and apoptosis-associated gene expression in the substantia nigra of Parkinson's disease rats.
Parkinson Disease
Endurance exercise training suppresses Parkinson disease-induced overexpression of apoptotic mediators in the heart.
Parkinson Disease
Gene disruption of caspase-3 prevents MPTP-induced Parkinson's disease in mice.
Parkinson Disease
Heat shock protein-70 (Hsp-70) suppresses paraquat-induced neurodegeneration by inhibiting JNK and caspase-3 activation in Drosophila model of Parkinson's disease.
Parkinson Disease
Implication of Caspase-3 as a Common Therapeutic Target for Multineurodegenerative Disorders and Its Inhibition Using Nonpeptidyl Natural Compounds.
Parkinson Disease
Increased caspase 3 and Bax immunoreactivity accompany nuclear GAPDH translocation and neuronal apoptosis in Parkinson's disease.
Parkinson Disease
Involvement of the mitochondrial apoptotic pathway and nitric oxide synthase in dopaminergic neuronal death induced by 6-hydroxydopamine and lipopolysaccharide.
Parkinson Disease
Is Bax a mitochondrial mediator in apoptotic death of dopaminergic neurons in Parkinson's disease?
Parkinson Disease
Loss of Non-Apoptotic Role of Caspase-3 in the PINK1 Mouse Model of Parkinson's Disease.
Parkinson Disease
Neuroprotective effects of echinacoside in the mouse MPTP model of Parkinson's disease.
Parkinson Disease
Parkinson disease-induced upregulation of apoptotic mediators could be attenuated in the skeletal muscle following chronic exercise training.
Parkinson Disease
PARP1 and CASP3 gene expression in a patient with multiple head and neck squamous cell carcinoma and Parkinson disease.
Parkinson Disease
Peripheral markers of apoptosis in Parkinson's disease: the effect of dopaminergic drugs.
Parkinson Disease
Peripheral proteasome and caspase activity in Parkinson disease and Alzheimer disease.
Parkinson Disease
Progressive degeneration of dopamine neurons in 6-hydroxydopamine rat model of Parkinson's disease does not involve activation of caspase-9 and caspase-3.
Parkinson Disease
Protective effects of kidney-tonifying Chinese herbal preparation on substantia nigra neurons in a mouse model of Parkinson's disease.
Parkinson Disease
Sensitive detection of caspase-3 enzymatic activities and inhibitor screening by mass spectrometry with dual maleimide labelling quantitation.
Parkinson Disease
Targeting caspase-3 as dual therapeutic benefits by RNAi facilitating brain-targeted nanoparticles in a rat model of Parkinson's disease.
Parkinson Disease
The neuroprotective effect of nicotine in Parkinson's disease models is associated with inhibiting PARP-1 and caspase-3 cleavage.
Parkinson Disease
The Protective Effect of Korean Red Ginseng Against Rotenone-Induced Parkinson's Disease in Rat Model: Modulation of Nuclear Factor-?? and Caspase-3.
Parkinson Disease
Transcription- and phosphorylation-dependent control of a functional interplay between XBP1s and PINK1 governs mitophagy and potentially impacts Parkinson disease pathophysiology.
Parkinson Disease
Zonisamide Attenuates MPP(+)-Induced Oxidative Toxicity Through Modulation of Ca(2+) Signaling and Caspase-3 Activity in Neuronal PC12 Cells.
Parkinson Disease
[P38MAPK pathway regulates COX-2 and caspase-3 expression in a mouse model of Parkinson disease.]
Parkinsonian Disorders
Endurance exercise training suppresses Parkinson disease-induced overexpression of apoptotic mediators in the heart.
Parkinsonian Disorders
Failure of caspase inhibition in the double-lesion rat model of striatonigral degeneration (multiple system atrophy).
Parkinsonian Disorders
Flavin-containing monooxygenase, a new clue of pathological proteins in the rotenone model of parkinsonism.
Parkinsonian Disorders
Gene disruption of caspase-3 prevents MPTP-induced Parkinson's disease in mice.
Parkinsonian Disorders
Intervention of mitochondrial dysfunction-oxidative stress-dependent apoptosis as a possible neuroprotective mechanism of ?-lipoic acid against rotenone-induced parkinsonism and L-dopa toxicity.
Parkinsonian Disorders
Isoflavone Attenuates the Caspase-1 and Caspase-3 Level in Cell Model of Parkinsonism.
Parkinsonian Disorders
Parkinson disease-induced upregulation of apoptotic mediators could be attenuated in the skeletal muscle following chronic exercise training.
Parkinsonian Disorders
The parkinsonian neurotoxin rotenone activates calpain and caspase-3 leading to motoneuron degeneration in spinal cord of Lewis rats.
Parvoviridae Infections
Induction of programmed cell death by parvovirus H-1 in U937 cells: connection with the tumor necrosis factor alpha signalling pathway.
Pemphigus
Biphasic activation of p38MAPK suggests that apoptosis is a downstream event in pemphigus acantholysis.
Pemphigus
Feasibility study for clinical application of caspase-3 inhibitors in Pemphigus vulgaris.
Pemphigus
Preclinical studies identify non-apoptotic low-level caspase-3 as therapeutic target in pemphigus vulgaris.
Periodontal Cyst
Immunohistochemical profile of the anti-apoptosis, apoptosis and proliferation markers Bcl-2, caspase-3, p53, and Ki-67 in botryoid odontogenic cysts compared to lateral periodontal cysts and gingival cysts of the adult.
Periodontitis
Effect of endoplasmic reticulum stress-induced apoptosis in the role of periodontitis on vascular calcification in a rat model.
Periodontitis
Evaluation of the effect of oleuropein on alveolar bone loss, inflammation, and apoptosis in experimental periodontitis.
Periodontitis
Porphyromonas gingivalis Differentially Modulates Apoptosome Apoptotic Peptidase Activating Factor 1 in Epithelial Cells and Fibroblasts.
Periodontitis
Regulation of Anti-Apoptotic SOD2 and BIRC3 in Periodontal Cells and Tissues.
Peripheral Nerve Injuries
Effects of exogenous neurotrophin-3 on myocyte apoptosis and Ca(2+)-ATP enzyme levels following nerve injury in rats.
Peripheral Nerve Injuries
Investigation of the effect of telmisartan on experimentally induced peripheral nerve injury in rats.
Peripheral Nervous System Diseases
Peripheral neuropathy in the Twitcher mouse involves the activation of axonal caspase 3.
Peripheral Nervous System Diseases
Protective effect of acetyl-L-carnitine on the apoptotic pathway of peripheral neuropathy.
Peripheral Nervous System Diseases
Vitamin E and 5-amino salicylic acid ameliorates acrylamide-induced peripheral neuropathy by inhibiting caspase-3 and inducible nitric oxide synthase immunoexpression.
Peritoneal Neoplasms
Fluorescence lifetime imaging microscopy of chemotherapy-induced apoptosis resistance in a syngenic mouse tumor model.
Peritonitis
Deletion of the adenosine A2A receptor increases the survival rate in a mice model of polymicrobial sepsis.
Peritonitis
Levosimendan attenuates multiple organ injury and improves survival in peritonitis-induced septic shock: studies in a rat model.
Peritonitis
The value of CRP, IL-6, leptin, cortisol, and peritoneal caspase-3 monitoring in the operative strategy of secondary peritonitis.
Persistent Infection
Increased expressions of ADAMTS-13 and apoptosis contribute to neuropathology during Toxoplasma gondii encephalitis in mice.
Persistent Infection
Tula orthohantavirus nucleocapsid protein is cleaved in infected cells and may sequester activated caspase-3 during persistent infection to suppress apoptosis.
Pheochromocytoma
Attenuation of Abeta-induced apoptosis of plant extract (Saengshik) mediated by the inhibition of mitochondrial dysfunction and antioxidative effect.
Pheochromocytoma
Attenuation of LPS-induced apoptosis in NGF-differentiated PC12 cells via NF-?B pathway and regulation of cellular redox status by an oxazine derivative.
Pheochromocytoma
Beyond the 5-HT3 receptors: A role for ?7nACh receptors in neuroprotective aspects of tropisetron.
Pheochromocytoma
Caspase-3-dependent proteolytic cleavage of protein kinase Cdelta is essential for oxidative stress-mediated dopaminergic cell death after exposure to methylcyclopentadienyl manganese tricarbonyl.
Pheochromocytoma
Cyanidin-3-O-Glucoside Protects PC12 Cells Against Neuronal Apoptosis Mediated by LPS-Stimulated BV2 Microglial Activation.
Pheochromocytoma
Ergothioneine rescues PC12 cells from beta-amyloid-induced apoptotic death.
Pheochromocytoma
MiR-199a-5p regulates sirtuin1 and PI3K in the rat hippocampus with intrauterine growth restriction.
Pheochromocytoma
Nitric oxide induces apoptosis via AP-1-driven upregulation of COX-2 in rat pheochromocytoma cells.
Pheochromocytoma
Propofol attenuates oxidative stress-induced PC12 cell injury via p38 MAP kinase dependent pathway.
Pheochromocytoma
Pulsed electromagnetic field and relief of hypoxia-induced neuronal cell death: The signaling pathway.
Pheochromocytoma
Supraphysiological doses of performance enhancing anabolic-androgenic steroids exert direct toxic effects on neuron-like cells.
Pheochromocytoma
Synthesis and in vitro evaluation of novel 1,2,4-triazine derivatives as neuroprotective agents.
Pheochromocytoma
Synthesis and initial in vitro biological evaluation of two new zinc-chelating compounds: comparison with TPEN and PAC-1.
Photosensitivity Disorders
In vitro photodynamic therapy with chlorin e6 leads to apoptosis of human vascular smooth muscle cells.
Photosensitivity Disorders
Photodynamic therapy-induced death of MCF-7 human breast cancer cells: a role for caspase-3 in the late steps of apoptosis but not for the critical lethal event.
Photosensitivity Disorders
Photosensitization with zinc (II) phthalocyanine as a switch in the decision between apoptosis and necrosis.
Pick Disease of the Brain
Expression of transcription factors c-Fos, c-Jun, CREB-1 and ATF-2, and caspase-3 in relation with abnormal tau deposits in Pick's disease.
Pilomatrixoma
Comparative Immunohistochemical Analyses on the Modes of Cell Death/Keratinization in Epidermal Cyst, Trichilemmal Cyst, and Pilomatricoma.
Pituitary Neoplasms
Alpha1-adrenergic receptor antagonists: novel therapy for pituitary adenomas.
Pituitary Neoplasms
Positive feedback of protein kinase C proteolytic activation during apoptosis.
Plague
Modified caspase-3 assay indicates correlation of caspase-3 activity with immunity of nonhuman primates to Yersinia pestis infection.
Plasmacytoma
E mu-bcl-2 transgene facilitates spontaneous transformation of early pre-B and immunoglobulin-secreting cells but not T cells.
Plasmacytoma
Immunolocalization of the ICE/Ced-3-family protease, CPP32 (Caspase-3), in non-Hodgkin's lymphomas, chronic lymphocytic leukemias, and reactive lymph nodes.
Pneumoconiosis
[Regulation role of superoxide dismutase coenzyme on Fas/FasL signal transduction and apoptosis in alveolar macrophages of pneonoconiosis patients]
Pneumonia
Acute Alcohol Intoxication Impairs the Hematopoietic Precursor Cell Response to Pneumococcal Pneumonia.
Pneumonia
Bleomycin-induced pulmonary toxicopathological changes in rats and its prevention by walnut extract.
Pneumonia
CD11b+ and Sca-1+ Cells Exert the Main Beneficial Effects of Systemically Administered Bone Marrow-Derived Mononuclear Cells in a Murine Model of Mixed Th2/Th17 Allergic Airway Inflammation.
Pneumonia
Cigarette smoke extract-induced suppression of caspase-3-like activity impairs human neutrophil phagocytosis.
Pneumonia
Diabetes increases pancreatitis induced systemic inflammation but has little effect on inflammation and cell death in the lung.
Pneumonia
Examining the Effector Mechanisms of the Feishu Acupoint (BL13) in the Treatment of Pneumonia Based on Systematic Acupuncture and Moxibustion Research.
Pneumonia
Influenza circulating strains in Argentina exhibit differential induction of cytotoxicity and caspase-3 in vitro.
Pneumonia
Low-molecular-mass hyaluronan induces pulmonary inflammation by up-regulation of Mcl-1 to inhibit neutrophil apoptosis via PI3K/Akt1 pathway.
Pneumonia
Lung tissue mitochondrial benzodiazepine receptors increase in a model of pulmonary inflammation.
Pneumonia
P21 regulates TGF-beta1-induced pulmonary responses via a TNF-alpha-signaling pathway.
Pneumonia
Protective Effects of Acupuncture in Cardiopulmonary Bypass-Induced Lung Injury in Rats.
Pneumonia
Silencing of fas, fas-associated via death domain, or caspase 3 differentially affects lung inflammation, apoptosis, and development of trauma-induced septic acute lung injury.
Pneumonia
Surfactant Proteins SP-A and SP-D Ameliorate Pneumonia Severity and Intestinal Injury in a Murine Model of Staphylococcus Aureus Pneumonia.
Pneumonia
Therapeutic Effects of Hyaluronic Acid Against Cytotoxic Extracellular Vesicles Released During Pseudomonas Aeruginosa Pneumonia.
Pneumoperitoneum
Room air versus carbon dioxide pneumoperitoneum: effects on oxidative state, apoptosis and histology of splanchnic organs.
Pneumoperitoneum
Study on the inhibition of hyperthermic CO2 pneumoperitoneum on the proliferation and migration of colon cancer cells and its mechanism.
Pneumovirus Infections
Granzyme A- and B-cluster deficiency delays acute lung injury in pneumovirus-infected mice.
Polycystic Kidney Diseases
Caspase inhibition reduces tubular apoptosis and proliferation and slows disease progression in polycystic kidney disease.
Polycystic Kidney Diseases
Caspase-3 gene deletion prolongs survival in polycystic kidney disease.
Polycystic Ovary Syndrome
Autophagy in ovary and polycystic ovary syndrome: role, dispute and future perspective.
Porcine Reproductive and Respiratory Syndrome
Mosla scabra flavonoids ameliorate the influenza A virus-induced lung injury and water transport abnormality via the inhibition of PRR and AQP signaling pathways in mice.
Pre-Eclampsia
Apoptosis and expression of Bcl-2, Bax, p53, caspase-3, and Fas, Fas ligand in placentas complicated by preeclampsia.
Pre-Eclampsia
Effect of hypoxia on expression of placental trophoblast cells SATB1 and ?-catenin and its correlation with the pathogenesis of preeclampsia.
Pre-Eclampsia
Expression of nuclear factor-kappa B and placental apoptosis in pregnancies complicated with intrauterine growth restriction and preeclampsia: an immunohistochemical study.
Pre-Eclampsia
Placental apoptosis in preeclampsia, intrauterine growth retardation, and HELLP syndrome: an immunohistochemical study with caspase-3 and bcl-2.
Pre-Eclampsia
PP128. Placental Caspase-3 gene polymorphisms is associated with preeclampsia.
Pre-Eclampsia
The association of the placental CASPASE-3 gene polymorphisms and preeclampsia susceptibility and in-silico analysis.
Pre-Eclampsia
[Correlation of oxidized low-density lipoprotein and lectin-like oxidized low-density lipoprotein receptor-1 with pre-eclampsia]
Pre-Eclampsia
[Expression of lectin-liked oxidized low density lipoprotein receptor-1 and apoptosis associated genes in placenta and the relationship thereof with morbility of early-onset preeclampsia]
Pre-Eclampsia
[Relationship between the expressions of lectin-like oxidized low-density lipoprotein receptor-1 and apoptosis associated genes in placenta tissues and the pathogenesis of preeclampsia]
Precursor B-Cell Lymphoblastic Leukemia-Lymphoma
Inhibition of telomerase using BIBR1532 enhances doxorubicin-induced apoptosis in pre-B acute lymphoblastic leukemia cells.
Precursor Cell Lymphoblastic Leukemia-Lymphoma
Beauvericin induces cytotoxic effects in human acute lymphoblastic leukemia cells through cytochrome c release, caspase 3 activation: the causative role of calcium.
Precursor Cell Lymphoblastic Leukemia-Lymphoma
Caspase 2 and caspase 3 as predictors of complete remission and survival in adults with acute lymphoblastic leukemia.
Precursor Cell Lymphoblastic Leukemia-Lymphoma
Cytochrome c-related caspase-3 activation determines treatment response and relapse in childhood precursor B-cell ALL.
Precursor Cell Lymphoblastic Leukemia-Lymphoma
Fish-Oil-Derived DHA-mediated Enhancement of Apoptosis in Acute Lymphoblastic Leukemia Cells is Associated with Accumulation of p53, Downregulation of Survivin, and Caspase-3 Activation.
Precursor Cell Lymphoblastic Leukemia-Lymphoma
Fish-oil-derived eicosapentaenoic acid decreases survivin expression and induces wt-p53 accumulation with caspase-3 activation in acute lymphoblastic leukemia cells.
Precursor Cell Lymphoblastic Leukemia-Lymphoma
Inhibiting Polo-like kinase 1 causes growth reduction and apoptosis in pediatric acute lymphoblastic leukemia cells.
Precursor Cell Lymphoblastic Leukemia-Lymphoma
Inhibition of telomerase using BIBR1532 enhances doxorubicin-induced apoptosis in pre-B acute lymphoblastic leukemia cells.
Precursor Cell Lymphoblastic Leukemia-Lymphoma
Low mRNA expression of the apoptosis-related genes CASP3, CASP8, and FAS is associated with low induction treatment response in childhood acute lymphoblastic leukemia (ALL).
Precursor Cell Lymphoblastic Leukemia-Lymphoma
Preclinical assessment of FHIT gene replacement therapy in human leukemia using a chimeric adenovirus, Ad5/F35.
Precursor Cell Lymphoblastic Leukemia-Lymphoma
Prognostic Value of CD95, Active Caspase-3, and Bcl-2 Expression in Adult Patients with De Novo Acute Lymphoblastic Leukemia.
Precursor Cell Lymphoblastic Leukemia-Lymphoma
Proliferation and apoptosis in acute and chronic leukemias and myelodysplastic syndrome.
Precursor Cell Lymphoblastic Leukemia-Lymphoma
Purification and characterization of a cytotoxic neurotoxin-like protein from Naja haje haje venom that induces mitochondrial apoptosis pathway.
Precursor Cell Lymphoblastic Leukemia-Lymphoma
Relapse in childhood acute lymphoblastic leukemia is associated with a decrease of the Bax/Bcl-2 ratio and loss of spontaneous caspase-3 processing in vivo.
Precursor Cell Lymphoblastic Leukemia-Lymphoma
Resveratrol: Isolation, and Its Nanostructured, Inhibits Cell Proliferation, Induces Cell Apoptosis in Certain Human Cell Lines Carcinoma and Exerts Protective Effect Against Paraquat-Induced Hepatotoxicity.
Precursor Cell Lymphoblastic Leukemia-Lymphoma
Searching in mother nature for anti-cancer activity: anti-proliferative and pro-apoptotic effect elicited by green barley on leukemia/lymphoma cells.
Precursor Cell Lymphoblastic Leukemia-Lymphoma
The clinical significance of caspase regulation in acute leukemia.
Precursor Cell Lymphoblastic Leukemia-Lymphoma
The Inhibitory Effect of Epigallocatechin Gallate on the Viability of T Lymphoblastic Leukemia Cells is Associated with Increase of Caspase-3 Level and Fas Expression.
Precursor Cell Lymphoblastic Leukemia-Lymphoma
[Modified alkaloids from Chelidonium majus L. induce G2/M arrest, caspase-3 activation, and apoptosis in human acute lymphoblastic leukemia MT-4 cells]
Precursor T-Cell Lymphoblastic Leukemia-Lymphoma
A novel long non-coding RNA T-ALL-R-LncR1 knockdown and Par-4 cooperate to induce cellular apoptosis in T-cell acute lymphoblastic leukemia cells.
Precursor T-Cell Lymphoblastic Leukemia-Lymphoma
BRD4 PROTAC degrader ARV-825 inhibits T-cell acute lymphoblastic leukemia by targeting 'Undruggable' Myc-pathway genes.
Precursor T-Cell Lymphoblastic Leukemia-Lymphoma
Differential targets and subcellular localization of antitumor alkyl-lysophospholipid in leukemic versus solid tumor cells.
Precursor T-Cell Lymphoblastic Leukemia-Lymphoma
Emerging Effects of Sepantronium Bromide (YM155) on MOLT-4 Cell Line Apoptosis Induction and Expression of Critical Genes Involved in Apoptotic Pathways.
Precursor T-Cell Lymphoblastic Leukemia-Lymphoma
Inhibition of phosphatidylinositol 3'-kinase induces preferentially killing of PTEN-null T leukemias through AKT pathway.
Precursor T-Cell Lymphoblastic Leukemia-Lymphoma
Mechanisms of JP-8 jet fuel toxicity. I. Induction of apoptosis in rat lung epithelial cells.
Precursor T-Cell Lymphoblastic Leukemia-Lymphoma
Proapoptotic activity and chemosensitizing effect of the novel Akt inhibitor (2S)-1-(1H-Indol-3-yl)-3-[5-(3-methyl-2H-indazol-5-yl)pyridin-3-yl]oxypropan2-amine (A443654) in T-cell acute lymphoblastic leukemia.
Precursor T-Cell Lymphoblastic Leukemia-Lymphoma
Prognostic Value of CD95, Active Caspase-3, and Bcl-2 Expression in Adult Patients with De Novo Acute Lymphoblastic Leukemia.
Premature Birth
Preconditioning the uterine unfolded protein response maintains non-apoptotic Caspase 3-dependent quiescence during pregnancy.
Presbycusis
Correlation of PDCD5 and apoptosis in hair cells and spiral ganglion neurons of different age of C57BL/6J mice.
Presbycusis
[Expression of PDCD5 and caspase 3 in the cochlea of different age of C57BL/6J mice].
Pressure Ulcer
[The expressions and functions of inflammatory cytokines, growth factors and apoptosis factors in the late stage of pressure ulcer chronic wounds].
Primary Ovarian Insufficiency
Premature ovarian failure with 46,XX,t(1;4)(p34.1;q34): first case report and literature review.
Prion Diseases
Expression of excitatory amino acid transporter-1 (EAAT-1) in brain macrophages and microglia of patients with prion diseases.
Prion Diseases
Role of glycosylphosphatidylinositols in the activation of phospholipase A2 and the neurotoxicity of prions.
Prostatic Diseases
Berbamine inhibited the growth of prostate cancer cells in vivo and in vitro via triggering intrinsic pathway of apoptosis.
Prostatic Hyperplasia
Apoptosis profiles in benign prostatic hyperplasia: close associations of cell kinetics with percent area density of histologic composition.
Prostatic Hyperplasia
Caspase 3 expression in benign prostatic hyperplasia and prostate carcinoma.
Prostatic Hyperplasia
Caspase-3/CPP32 immunoreactivity and its correlation with frequency of apoptotic bodies in human prostatic carcinomas and benign nodular hyperplasias.
Prostatic Hyperplasia
Effect of Veratrum maackii on Testosterone Propionate-Induced Benign Prostatic Hyperplasia in Rats.
Prostatic Hyperplasia
Expression of livin, survivin and caspase-3 in prostatic cancer and their clinical significance.
Prostatic Hyperplasia
Serenoa repens treatment modifies bax/bcl-2 index expression and caspase-3 activity in prostatic tissue from patients with benign prostatic hyperplasia.
Prostatic Hyperplasia
[Expression of Ki-67, Bcl-2,Bax and caspase-3 in benign prostatic hyperplasia combined with prostatitis and their significances]
Prostatic Intraepithelial Neoplasia
Inhibitory Effect of Orally Administered 5-Aminolevulinic Acid on Prostate Carcinogenesis in the FVB-Transgenic Adenocarcinoma of a Mouse Prostate (FVB-TRAMP) Model.
Prostatic Neoplasms
2'-Hydroxy-4-methylsulfonylchalcone enhances TRAIL-induced apoptosis in prostate cancer cells.
Prostatic Neoplasms
6-(3,4-Dihydro-1H-isoquinoline-2-yl)-N-(6-methoxypyridine-2-yl) nicotinamide-26 (DIMN-26) decreases cell proliferation by induction of apoptosis and downregulation of androgen receptor signaling in human prostate cancer cells.
Prostatic Neoplasms
?-Santalol, a derivative of sandalwood oil, induces apoptosis in human prostate cancer cells by causing caspase-3 activation.
Prostatic Neoplasms
A novel 3',5'-diprenylated chalcone induces concurrent apoptosis and GSDME-dependent pyroptosis through activating PKC?/JNK signal in prostate cancer.
Prostatic Neoplasms
A novel HSP90 inhibitor delays castrate resistant prostate cancer without altering serum PSA levels and inhibits osteoclastogenesis.
Prostatic Neoplasms
A Study of the Anti-Cancer Effects of the Hexane Fraction of the Methanol Extract of Forsythiae Fructus.
Prostatic Neoplasms
Activation of AMP-kinase by AICAR induces apoptosis of DU-145 prostate cancer cells through generation of reactive oxygen species and activation of c-Jun N-terminal kinase.
Prostatic Neoplasms
Alpha1-adrenoceptor antagonists radiosensitize prostate cancer cells via apoptosis induction.
Prostatic Neoplasms
Amygdalin induces apoptosis through regulation of Bax and Bcl-2 expressions in human DU145 and LNCaP prostate cancer cells.
Prostatic Neoplasms
An ?-acetoxy-tirucallic acid isomer inhibits Akt/mTOR signaling and induces oxidative stress in prostate cancer cells.
Prostatic Neoplasms
Anti-cancer effect of ursolic acid activates apoptosis through ROCK/PTEN mediated mitochondrial translocation of cofilin-1 in prostate cancer.
Prostatic Neoplasms
Anti-tumor activities of andrographolide, a diterpene from Andrographis paniculata, by inducing apoptosis and inhibiting VEGF level.
Prostatic Neoplasms
Anticarcinogenic effect of FTY720 in human prostate carcinoma DU145 cells: modulation of mitogenic signaling, FAK, cell-cycle entry and apoptosis.
Prostatic Neoplasms
Antineoplastic effect of beta-elemene on prostate cancer cells and other types of solid tumour cells.
Prostatic Neoplasms
Antioxidant activity of growth hormone-releasing hormone antagonists in LNCaP human prostate cancer line.
Prostatic Neoplasms
Apoptosis induction in prostate cancer cells by a novel gene product, pHyde, involves caspase-3.
Prostatic Neoplasms
Apoptotic activity and mechanism of 2-cyano-3,12-dioxoolean-1,9-dien-28-oic-acid and related synthetic triterpenoids in prostate cancer.
Prostatic Neoplasms
Artocarpus altilis (Parkinson) Fosberg Extracts and Geranyl Dihydrochalcone Inhibit STAT3 Activity in Prostate Cancer DU145 Cells.
Prostatic Neoplasms
Association of CASP3 genetic polymorphisms rs1049216, rs2705897 and rs4647603 with the risk of prostate cancer in Galicia (NW Spain).
Prostatic Neoplasms
Auraptene Induces Apoptosis via Myeloid Cell Leukemia 1-Mediated Activation of Caspases in PC3 and DU145 Prostate Cancer Cells.
Prostatic Neoplasms
Beneficial effects of genistein in suppression of proliferation, inhibition of metastasis, and induction of apoptosis in PC3 prostate cancer cells.
Prostatic Neoplasms
BMD188, A novel hydroxamic acid compound, demonstrates potent anti-prostate cancer effects in vitro and in vivo by inducing apoptosis: requirements for mitochondria, reactive oxygen species, and proteases.
Prostatic Neoplasms
Breviscapine (BVP) inhibits prostate cancer progression through damaging DNA by minichromosome maintenance protein-7 (MCM-7) modulation.
Prostatic Neoplasms
Carnosic acid modulates Akt/IKK/NF-?B signaling by PP2A and induces intrinsic and extrinsic pathway mediated apoptosis in human prostate carcinoma PC-3 cells.
Prostatic Neoplasms
Caspase 3 expression in benign prostatic hyperplasia and prostate carcinoma.
Prostatic Neoplasms
Characterisation of a Tip60 specific inhibitor, NU9056, in prostate cancer.
Prostatic Neoplasms
Characterization of 3alpha-acetyl-11-keto-alpha-boswellic acid, a pentacyclic triterpenoid inducing apoptosis in vitro and in vivo.
Prostatic Neoplasms
Chronic administration of valproic acid inhibits prostate cancer cell growth in vitro and in vivo.
Prostatic Neoplasms
Combination of Quercetin and 2-Methoxyestradiol Enhances Inhibition of Human Prostate Cancer LNCaP and PC-3 Cells Xenograft Tumor Growth.
Prostatic Neoplasms
Comparison of ACINUS, caspase-3, and TUNEL as apoptotic markers in determination of tumor growth rates of clinically localized prostate cancer using image analysis.
Prostatic Neoplasms
CXCR4-gp120-IIIB interactions induce caspase-mediated apoptosis of prostate cancer cells and inhibit tumor growth.
Prostatic Neoplasms
Cyclooxygenase 2 rescues LNCaP prostate cancer cells from sanguinarine-induced apoptosis by a mechanism involving inhibition of nitric oxide synthase activity.
Prostatic Neoplasms
Cyclooxygenase-2 inhibitor celecoxib augments chemotherapeutic drug-induced apoptosis by enhancing activation of caspase-3 and -9 in prostate cancer cells.
Prostatic Neoplasms
Delphinidin induces apoptosis via cleaved HDAC3-mediated p53 acetylation and oligomerization in prostate cancer cells.
Prostatic Neoplasms
Design, synthesis and apoptosis inducing effect of novel (Z)-3-(3'-methoxy-4'-(2-amino-2-oxoethoxy)-benzylidene)indolin-2-ones as potential antitumour agents.
Prostatic Neoplasms
Desipramine-induced apoptosis in human PC3 prostate cancer cells: activation of JNK kinase and caspase-3 pathways and a protective role of [Ca2+]i elevation.
Prostatic Neoplasms
Dihydrotestosterone enhances transforming growth factor-beta-induced apoptosis in hormone-sensitive prostate cancer cells.
Prostatic Neoplasms
Diosmetin suppresses human prostate cancer cell proliferation through the induction of apoptosis and cell cycle arrest.
Prostatic Neoplasms
Dual targeting of mTORC1 and mTORC2 by INK-128 potently inhibits human prostate cancer cell growth in vitro and in vivo.
Prostatic Neoplasms
E1A oncogene expression inhibits PTHrP P3 promoter activity and sensitizes human prostate cancer cells to TNF-induced apoptosis.
Prostatic Neoplasms
Early induction of apoptosis in androgen-independent prostate cancer cell line by FTY720 requires caspase-3 activation.
Prostatic Neoplasms
Effect of AQP9 Expression in Androgen-Independent Prostate Cancer Cell PC3.
Prostatic Neoplasms
Endoplasmic reticulum stress, autophagic and apoptotic cell death, and immune activation by a natural triterpenoid in human prostate cancer cells.
Prostatic Neoplasms
Enhanced induction of apoptosis by combined treatment of human carcinoma cells with X rays and death receptor agonists.
Prostatic Neoplasms
Enhanced therapeutic effect of cisplatin on the prostate cancer in tumor-bearing mice by transfecting the attenuated Salmonella carrying a plasmid co-expressing p53 gene and mdm2 siRNA.
Prostatic Neoplasms
Expression of livin, survivin and caspase-3 in prostatic cancer and their clinical significance.
Prostatic Neoplasms
Fibronectin protects prostate cancer cells from tumor necrosis factor-alpha-induced apoptosis via the AKT/survivin pathway.
Prostatic Neoplasms
Finasteride induces apoptosis via Bcl-2, Bcl-xL, Bax and caspase-3 proteins in LNCaP human prostate cancer cell line.
Prostatic Neoplasms
FTY720, a synthetic compound from Isaria sinclairii, inhibits proliferation and induces apoptosis in pancreatic cancer cells.
Prostatic Neoplasms
Functional characterization and anti-cancer action of the clinical phase II cardiac Na+/K+ ATPase inhibitor istaroxime: in vitro and in vivo properties and cross talk with the membrane androgen receptor.
Prostatic Neoplasms
Genetic Variants in CASP3, BMP5, and IRS2 Genes May Influence Survival in Prostate Cancer Patients Receiving Androgen-Deprivation Therapy.
Prostatic Neoplasms
Ginkgetin induces apoptosis via activation of caspase and inhibition of survival genes in PC-3 prostate cancer cells.
Prostatic Neoplasms
Glycyrrhizin induces apoptosis in prostate cancer cell lines DU-145 and LNCaP.
Prostatic Neoplasms
HIV-1 protease inhibitor, ritonavir: a potent inhibitor of CYP3A4, enhanced the anticancer effects of docetaxel in androgen-independent prostate cancer cells in vitro and in vivo.
Prostatic Neoplasms
Hsa-miR-146a-5p modulates androgen-independent prostate cancer cells apoptosis by targeting ROCK1.
Prostatic Neoplasms
Human agonistic antibody to tumor necrosis factor-related apoptosis-inducing ligand receptor 2 induces cytotoxicity and apoptosis in prostate cancer and bladder cancer cells.
Prostatic Neoplasms
IL-8 protects prostate cancer cells from GSK-3?-induced oxidative stress by activating the mTOR signaling pathway.
Prostatic Neoplasms
Immunohistochemical expression of caspase-1 and -9, uncleaved caspase-3 and -6, cleaved caspase-3 and -6 as well as Bcl-2 in benign epithelium and cancer of the prostate.
Prostatic Neoplasms
In vitro anti-oxidant, cytotoxic and pro-apoptotic effects of Achillea teretifolia Willd extracts on human prostate cancer cell lines.
Prostatic Neoplasms
Induction of anoikis by doxazosin in prostate cancer cells is associated with activation of caspase-3 and a reduction of focal adhesion kinase.
Prostatic Neoplasms
Induction of apoptosis in hormone-resistant human prostate cancer PC3 cells by inactivated Sendai virus.
Prostatic Neoplasms
Induction of apoptosis in human cancer cells by TZT-1027, an antimicrotubule agent.
Prostatic Neoplasms
Induction of apoptosis in prostate cancer cell lines by a flavonoid, baicalin.
Prostatic Neoplasms
Induction of apoptosis in the LNCaP human prostate carcinoma cell line and prostate adenocarcinomas of SV40T antigen transgenic rats by the Bowman-Birk inhibitor.
Prostatic Neoplasms
Induction of morphological and biochemical apoptosis following prolonged mitotic blockage by halichondrin B macrocyclic ketone analog E7389.
Prostatic Neoplasms
Intracellular hydrogen peroxide production is an upstream event in apoptosis induced by down-regulation of casein kinase 2 in prostate cancer cells.
Prostatic Neoplasms
Ionically-crosslinked milk protein nanoparticles as flutamide carriers for effective anticancer activity in prostate cancer-bearing rats.
Prostatic Neoplasms
KAT5 Negatively regulates the proliferation of prostate cancer LNCaP cells via the caspase 3-dependent apoptosis pathway.
Prostatic Neoplasms
KNK437, a benzylidene lactam compound, sensitises prostate cancer cells to the apoptotic effect of hyperthermia.
Prostatic Neoplasms
Knockdown of zinc finger protein X-linked inhibits prostate cancer cell proliferation and induces apoptosis by activating caspase-3 and caspase-9.
Prostatic Neoplasms
LncRNA PVT1 predicts prognosis and regulates tumor growth in prostate cancer.
Prostatic Neoplasms
Loss of caspase-1 and caspase-3 protein expression in human prostate cancer.
Prostatic Neoplasms
Mangiferin inhibition of proliferation and induction of apoptosis in human prostate cancer cells is correlated with downregulation of B-cell lymphoma-2 and upregulation of microRNA-182.
Prostatic Neoplasms
Maspin sensitizes prostate cancer cells to doxazosin-induced apoptosis.
Prostatic Neoplasms
Membrane androgen receptor activation triggers down-regulation of PI-3K/Akt/NF-kappaB activity and induces apoptotic responses via Bad, FasL and caspase-3 in DU145 prostate cancer cells.
Prostatic Neoplasms
microRNA-323 upregulation promotes prostate cancer growth and docetaxel resistance by repressing p73.
Prostatic Neoplasms
MicroRNA-497 suppresses proliferation and induces apoptosis in prostate cancer cells.
Prostatic Neoplasms
Molecular mechanisms of resveratrol (3,4,5-trihydroxy-trans-stilbene) and its interaction with TNF-related apoptosis inducing ligand (TRAIL) in androgen-insensitive prostate cancer cells.
Prostatic Neoplasms
Molecular mechanisms of synergistic induction of apoptosis by the combination therapy with hyperthermia and cisplatin in prostate cancer cells.
Prostatic Neoplasms
Monocyte chemoattractant protein-1 modulates invasion and apoptosis of PC-3M prostate cancer cells via regulating expression of VEGF, MMP9 and caspase-3.
Prostatic Neoplasms
Moringa oleifera methanolic leaves extract induces apoptosis and G0/G1 cell cycle arrest via downregulation of Hedgehog Signaling Pathway in human prostate PC-3 cancer cells.
Prostatic Neoplasms
N-substituted piperazinopyridylsteroid derivatives as abiraterone analogues inhibit growth and induce pro-apoptosis in human hormone-independent prostate cancer cell lines.
Prostatic Neoplasms
Neoxanthin and fucoxanthin induce apoptosis in PC-3 human prostate cancer cells.
Prostatic Neoplasms
Nitric oxide donating nonsteroidal anti-inflammatory drugs induce apoptosis in human prostate cancer cell systems and human prostatic stroma via caspase-3.
Prostatic Neoplasms
NKX3.1 potentiates TNF-alpha/CHX-induced apoptosis of prostate cancer cells through increasing caspase-3 expression and its activity.
Prostatic Neoplasms
NVP-BEZ235, a dual PI3K/mTOR inhibitor, induces cell death through alternate routes in prostate cancer cells depending on the PTEN genotype.
Prostatic Neoplasms
PARP-1 and CASP3 genes are up-regulated in LNCaP and PC-3 prostate cancer cell lines.
Prostatic Neoplasms
PectaSol-C modified citrus pectin induces apoptosis and inhibition of proliferation in human and mouse androgen-dependent and- independent prostate cancer cells.
Prostatic Neoplasms
Phellinus linteus extract sensitizes advanced prostate cancer cells to apoptosis in athymic nude mice.
Prostatic Neoplasms
Piperine, a Bioactive Component of Pepper Spice Exerts Therapeutic Effects on Androgen Dependent and Androgen Independent Prostate Cancer Cells.
Prostatic Neoplasms
Possible relations between oxidative damage and apoptosis in benign prostate hyperplasia and prostate cancer patients.
Prostatic Neoplasms
Prognostic value of inhibitors of apoptosis proteins (IAPs) and caspases in prostate cancer: caspase-3 forms and XIAP predict biochemical progression after radical prostatectomy.
Prostatic Neoplasms
Proscillaridin A induces apoptosis, inhibits STAT3 activation and augments doxorubicin toxicity in prostate cancer cells.
Prostatic Neoplasms
Prostate cancer cell growth characteristics in serum and prostate-conditioned media from moderate-intensity exercise-trained healthy and tumor-bearing rats.
Prostatic Neoplasms
Proteasome Inhibitor Bortezomib Increases Radiation Sensitivity in Androgen Independent Human Prostate Cancer Cells.
Prostatic Neoplasms
Protection by Bcl-2 against apoptotic but not autophagic cell death after photodynamic therapy.
Prostatic Neoplasms
Quercetin-6-C-?-D-glucopyranoside, natural analog of quercetin exhibits anti-prostate cancer activity by inhibiting Akt-mTOR pathway via aryl hydrocarbon receptor.
Prostatic Neoplasms
Quinazoline-based alpha 1-adrenoceptor antagonists induce prostate cancer cell apoptosis via TGF-beta signalling and I kappa B alpha induction.
Prostatic Neoplasms
Reactive oxygen species mediate isoalantolactone-induced apoptosis in human prostate cancer cells.
Prostatic Neoplasms
Reduced pim-1 expression increases chemotherapeutic drug sensitivity in human androgen-independent prostate cancer cells by inducing apoptosis.
Prostatic Neoplasms
Restoration of fibroblast growth factor receptor 2IIIb enhances the chemosensitivity of human prostate cancer cells.
Prostatic Neoplasms
Salen-Mn compounds induces cell apoptosis in human prostate cancer cells through promoting AMPK activity and cell autophagy.
Prostatic Neoplasms
Saposin C promotes survival and prevents apoptosis via PI3K/Akt-dependent pathway in prostate cancer cells.
Prostatic Neoplasms
Sepia ink oligopeptide induces apoptosis in prostate cancer cell lines via caspase-3 activation and elevation of Bax/Bcl-2 ratio.
Prostatic Neoplasms
SGO1 induces proliferation and metastasis of prostate cancer through AKT-mediated signaling pathway.
Prostatic Neoplasms
Sildenafil increases chemotherapeutic efficacy of doxorubicin in prostate cancer and ameliorates cardiac dysfunction.
Prostatic Neoplasms
Suppression of BCL2 by Antisense Oligonucleotides and Compensation by Non-Targeted Genes May Enhance Tumor Proliferation.
Prostatic Neoplasms
Synthesis and study of the cancer cell growth inhibitory properties of alpha-, gamma-tocopheryl and gamma-tocotrienyl 2-phenylselenyl succinates.
Prostatic Neoplasms
Synthesis of procaspases-3 and -7 during apoptosis in prostate cancer cells.
Prostatic Neoplasms
Targeting cancer cell metabolism: the combination of metformin and 2-deoxyglucose induces p53-dependent apoptosis in prostate cancer cells.
Prostatic Neoplasms
Targeting receptor for advanced glycation end products (RAGE) expression induces apoptosis and inhibits prostate tumor growth.
Prostatic Neoplasms
The death of human cancer cells following photodynamic therapy: apoptosis competence is necessary for Bcl-2 protection but not for induction of autophagy.
Prostatic Neoplasms
The Effect of Exogenous Superoxide Dismutase (SOD) on Caspase-3 Activation and Apoptosis Induction in Pc-3 Prostate Cancer Cells.
Prostatic Neoplasms
The mediating role of caspase-3 protease in the intracellular mechanism of genistein-induced apoptosis in human prostatic carcinoma cell lines, DU145 and LNCaP.
Prostatic Neoplasms
The synthesis and characterization of a series of cobalt(II) ?-ketoaminato complexes and their cytotoxic activity towards human tumor cell lines.
Prostatic Neoplasms
The UCA1/miR-204/Sirt1 axis modulates docetaxel sensitivity of prostate cancer cells.
Prostatic Neoplasms
Vitamin k2, a naturally occurring menaquinone, exerts therapeutic effects on both hormone-dependent and hormone-independent prostate cancer cells.
Prostatic Neoplasms
Vitamin K4 induces tumor cytotoxicity in human prostate carcinoma PC-3 cells via the mitochondria-related apoptotic pathway.
Prostatic Neoplasms
VP1 of foot-and-mouth disease virus induces apoptosis via the Akt signaling pathway.
Prostatic Neoplasms
Wedelolactone, a medicinal plant-derived coumestan, induces caspase-dependent apoptosis in prostate cancer cells via downregulation of PKC? without inhibiting Akt.
Prostatic Neoplasms
[Changes in mitochondrial function induced by dequalinium precede oxidative stress and apoptosis in the human prostate cancer cell line PC-3].
Prostatic Neoplasms
[Expressions of Bcl-xl and caspase-3 in the prostate cancer tissue and their correlation].
Prostatic Neoplasms
[Investigation of antitumorigenic effects of food-borne non-pathogenic and pathogenic Salmonella enterica strains on MEF, DU145 and HeLa cell lines].
Prostatic Neoplasms
[Sanggenon C induces apoptosis of prostate cancer PC3 cells by activating caspase 3 and caspase 9 pathways].
Prostatitis
[Expression of Ki-67, Bcl-2,Bax and caspase-3 in benign prostatic hyperplasia combined with prostatitis and their significances]
protein acetyllysine n-acetyltransferase deficiency
SIRT3 deficiency delays diabetic skin wound healing via oxidative stress and necroptosis enhancement.
protein acetyllysine n-acetyltransferase deficiency
Sirt3 Deficiency Increased the Vulnerability of Pancreatic Beta Cells to Oxidative Stress-Induced Dysfunction.
protein acetyllysine n-acetyltransferase deficiency
Sirtuin 3 deficiency exacerbates diabetic cardiomyopathy via necroptosis enhancement and NLRP3 activation.
Proteinuria
1, 25-dihydroxyvitamin D3 decreases adriamycin-induced podocyte apoptosis and loss.
Proteinuria
Effect of Tongxinluo on Podocyte Apoptosis via Inhibition of Oxidative Stress and P38 Pathway in Diabetic Rats.
Proteinuria
Growth Arrest Specific Protein (Gas)-6/AXL Signaling Induces Preeclampsia (PE) in Rats.
Proteinuria
Heme oxygenase-1 inducer hemin attenuates the progression of remnant kidney model.
Proteinuria
Impact of bone-marrow-derived mesenchymal stem cells on adriamycin-induced chronic nephropathy.
Proteinuria
Preconditioning by aerobic exercise reduces acute ischemic renal injury in rats.
Proteinuria
Prostaglandin E2 promotes cell survival of glomerular epithelial cells via the EP4 receptor.
Psoriasis
An in silico appraisal to identify high affinity anti-apoptotic synthetic tetrapeptide inhibitors targeting the mammalian caspase 3 enzyme.
Psoriasis
Effect of alterations in apoptotic pathway on development of metabolic syndrome in patients with psoriasis vulgaris.
Psoriasis
Evaluating the effect of rice (Oryza sativa L.: SRNC05053-6-2) crude extract on psoriasis using in vitro and in vivo models.
Psoriasis
Expression Patterns of TNF?, MAdCAM1, and STAT3 in Intestinal and Skin Manifestations of Inflammatory Bowel Disease.
Psoriasis
Sortilin regulates keratinocyte proliferation and apoptosis through the PI3K-AKT signaling pathway.
Psoriasis
[Effect of combined therapy with Chinese drug and narrow broad ultraviolet B on Bcl-2, caspase-3 and survivin in skin lesion with psoriasis vulgaris]
Pulmonary Disease, Chronic Obstructive
Activation of the ubiquitin-proteasome pathway in the diaphragm in chronic obstructive pulmonary disease.
Pulmonary Disease, Chronic Obstructive
Adiponectin attenuates endoplasmic reticulum stress and alveolar epithelial apoptosis in COPD rats.
Pulmonary Disease, Chronic Obstructive
Altered expression of p21, activated caspase-3, and PCNA in bronchiolar epithelium of smokers with and without chronic obstructive pulmonary disease.
Pulmonary Disease, Chronic Obstructive
Analyze and Identify Peiminine Target EGFR Improve Lung Function and Alleviate Pulmonary Fibrosis to Prevent Exacerbation of Chronic Obstructive Pulmonary Disease by Phosphoproteomics Analysis.
Pulmonary Disease, Chronic Obstructive
Bufei Jianpi Granules Reduce Quadriceps Muscular Cell Apoptosis by Improving Mitochondrial Function in Rats with Chronic Obstructive Pulmonary Disease.
Pulmonary Disease, Chronic Obstructive
CFTR Regulation of Intracellular pH and Ceramides is Required for Lung Endothelial Cell Apoptosis.
Pulmonary Disease, Chronic Obstructive
Changes in the expression level of IL-17A and p53-fibrinolytic system in smokers with or without COPD.
Pulmonary Disease, Chronic Obstructive
Determining Pharmacological Mechanisms of Chinese Incompatible Herbs Fuzi and Banxia in Chronic Obstructive Pulmonary Disease: A Systems Pharmacology-Based Study.
Pulmonary Disease, Chronic Obstructive
Effect of cigarette smoke exposure and structural modifications on the alpha-1 antitrypsin interaction with caspases.
Pulmonary Disease, Chronic Obstructive
Endoplasmic reticulum, Golgi, and lysosomes are disorganized in lung fibroblasts from chronic obstructive pulmonary disease patients.
Pulmonary Disease, Chronic Obstructive
INFLAMMATORY CELLS AND APOPTOSIS IN RESPIRATORY AND LIMB MUSCLES OF PATIENTS WITH COPD.
Pulmonary Disease, Chronic Obstructive
Metabolic phenotype and adipose tissue inflammation in patients with chronic obstructive pulmonary disease.
Pulmonary Disease, Chronic Obstructive
miR-1307-3p overexpression inhibits cell proliferation and promotes cell apoptosis by targeting ISM1 in colon cancer.
Pulmonary Disease, Chronic Obstructive
Myopathological features in skeletal muscle of patients with chronic obstructive pulmonary disease.
Pulmonary Disease, Chronic Obstructive
Therapeutic sildenafil inhibits pulmonary damage induced by cigarette smoke exposure and bacterial inhalation in rats.
Pulmonary Disease, Chronic Obstructive
Uncovering Active Ingredients and Mechanisms of Spica Prunellae in the Treatment of Colon Adenocarcinoma: A Study Based on Network Pharmacology and Bioinformatics.
Pulmonary Edema
Caspase-1 Inhibitor Prevents Neurogenic Pulmonary Edema After Subarachnoid Hemorrhage in Mice.
Pulmonary Edema
MicroRNA-146a overexpression alleviates intestinal ischemia/reperfusion-induced acute lung injury in mice.
Pulmonary Edema
Therapeutic Effects of Hyaluronic Acid Against Cytotoxic Extracellular Vesicles Released During Pseudomonas Aeruginosa Pneumonia.
Pulmonary Emphysema
{alpha}-1 Antitrypsin Inhibits Caspase-3 Activity, Preventing Lung Endothelial Cell Apoptosis.
Pulmonary Fibrosis
Asbestos-Induced Pulmonary Fibrosis is Augmented in 8-Oxoguanine DNA Glycosylase (OGG1) Knockout mice.
Pulmonary Fibrosis
Attenuation of bleomycin-induced pulmonary fibrosis by intratracheal administration of antisense oligonucleotides against angiotensinogen mRNA.
Pulmonary Fibrosis
Autoantibody against caspase-3, an executioner of apoptosis, in patients with systemic sclerosis.
Pulmonary Fibrosis
Feasibility and Mechanism Analysis of Shenfu Injection in the Treatment of Idiopathic Pulmonary Fibrosis.
Pulmonary Fibrosis
Restoring microRNA-499-5p Protects Sepsis-Induced Lung Injury Mice Via Targeting Sox6.
Rabies
Impact of caspase-1/11, -3, -7, or IL-1?/IL-18 deficiency on rabies virus-induced macrophage cell death and onset of disease.
Rabies
Rabies virus infection of primary neuronal cultures and adult mice: failure to demonstrate evidence of excitotoxicity.
Rabies
Targeting caspase-3 as dual therapeutic benefits by RNAi facilitating brain-targeted nanoparticles in a rat model of Parkinson's disease.
Radicular Cyst
Immunohistochemical analysis of apoptosis-related factors in lining epithelium of radicular cysts.
Radicular Cyst
Possible role of apoptosis in the pathogenesis and clinical evolution of radicular cyst: an immunohistochemical study.
Radicular Cyst
Role of HIF-1? and CASPASE-3 in cystogenesis of odontogenic cysts and tumors.
Radiculopathy
[Effects of Chinese herbal medicine Yiqi Huayu Recipe on apoptosis of dorsal root ganglion neurons and expression of caspase-3 in rats with lumbar nerve root compression].
Rectal Fistula
Study on the Mechanism of Periplaneta americana Extract to Accelerate Wound Healing after Diabetic Anal Fistula Operation Based on Network Pharmacology.
Rectal Neoplasms
Association between main Caspase gene polymorphisms and the susceptibility and prognosis of colorectal cancer.
Rectal Neoplasms
[Effect of resveratrol in regulating proliferation and apoptosis of rectal cancer cells via up-regulating PTEN].
Relative Energy Deficiency in Sport
Mechanism of BMP and TG2 in mesenchymal stem cell osteogenesis.
Renal Insufficiency
Caspase-3-dependent peritubular capillary dysfunction is pivotal for the transition from acute to chronic kidney disease after acute ischemia-reperfusion injury.
Renal Insufficiency
Disruption of renal peritubular blood flow in lipopolysaccharide-induced renal failure: role of nitric oxide and caspases.
Renal Insufficiency
Methylmalonic acid administration induces DNA damage in rat brain and kidney.
Renal Insufficiency
Rokumi-jio-gan-Containing Prescriptions Attenuate Oxidative Stress, Inflammation, and Apoptosis in the Remnant Kidney.
Renal Insufficiency, Chronic
Chronic kidney disease causes defects in signaling through the insulin receptor substrate/phosphatidylinositol 3-kinase/Akt pathway: implications for muscle atrophy.
Renal Insufficiency, Chronic
Erythrocyte caspase-3 levels in children with chronic kidney disease.
Renal Insufficiency, Chronic
Structure-activity relationship of piperine and its synthetic amide analogs for therapeutic potential to prevent experimentally induced ER stress in vitro.
Reoviridae Infections
Caspase-3 activation is required for reovirus-induced encephalitis in vivo.
Reoviridae Infections
Novel strategy for treatment of viral central nervous system infection by using a cell-permeating inhibitor of c-Jun N-terminal kinase.
Reoviridae Infections
Synergistic cytotoxicity of oncolytic reovirus in combination with cisplatin-paclitaxel doublet chemotherapy.
Reperfusion Injury
Acute Intravenous Infusion of Immunoglobulins Protects Against Myocardial Ischemia-Reperfusion Injury Through Inhibition of Caspase-3.
Reperfusion Injury
Apoptosis in Ca2 + reperfusion injury of cultured astrocytes: roles of reactive oxygen species and NF-kappaB activation.
Reperfusion Injury
Apoptotic retinal neuronal death by ischemia-reperfusion is executed by two distinct caspase family proteases.
Reperfusion Injury
Atorvastatin improving renal ischemia reperfusion injury via direct inhibition of active caspase-3 in rats.
Reperfusion Injury
Calcitonin Gene-Related Peptide Downregulates Expression of Inducible Nitride Oxide Synthase and Caspase-3 after Intestinal Ischemia-Reperfusion Injury in Rats.
Reperfusion Injury
Carbon monoxide modulates Fas/Fas ligand, caspases, and Bcl-2 family proteins via the p38alpha mitogen-activated protein kinase pathway during ischemia-reperfusion lung injury.
Reperfusion Injury
Caspase-3 Is a Pivotal Regulator of Microvascular Rarefaction and Renal Fibrosis after Ischemia-Reperfusion Injury.
Reperfusion Injury
Caspase-3-dependent peritubular capillary dysfunction is pivotal for the transition from acute to chronic kidney disease after acute ischemia-reperfusion injury.
Reperfusion Injury
Clearance of damaged mitochondria via mitophagy is important to the protective effect of ischemic preconditioning in kidneys.
Reperfusion Injury
Comparative effects of methylprednisolone and tetracosactide (ACTH1-24) on ischemia/reperfusion injury of the rabbit spinal cord.
Reperfusion Injury
Curcumin prevents reperfusion injury following ischemic stroke in rats via inhibition of NF??B, ICAM-1, MMP-9 and caspase-3 expression.
Reperfusion Injury
Cyclic Helix B Peptide in Preservation Solution and Autologous Blood Perfusate Ameliorates Ischemia-Reperfusion Injury in Isolated Porcine Kidneys.
Reperfusion Injury
d-Pinitol protects against endoplasmic reticulum stress and apoptosis in hepatic ischemia-reperfusion injury via modulation of AFT4-CHOP/GRP78 and caspase-3 signaling pathways.
Reperfusion Injury
Detection of Myocardial Ischemia-Reperfusion Injury Using a Fluorescent Near-Infrared Zinc(ii)-Dipicolylamine Probe and (99m)Tc Glucarate.
Reperfusion Injury
Detection of myocardial ischemia-reperfusion injury using a fluorescent near-infrared zinc(II)-dipicolylamine probe and 99mTc glucarate.
Reperfusion Injury
Dexmedetomidine attenuates spinal cord ischemia-reperfusion injury through both anti-inflammation and anti-apoptosis mechanisms in rabbits.
Reperfusion Injury
Differential effects of caspase inhibitors on the renal dysfunction and injury caused by ischemia-reperfusion of the rat kidney.
Reperfusion Injury
Edaravone alleviates cell apoptosis and mitochondrial injury in ischemia-reperfusion-induced kidney injury via the JAK/STAT pathway.
Reperfusion Injury
Effect of aloe polysaccharide on caspase-3 expression following cerebral ischemia and reperfusion injury in rats.
Reperfusion Injury
Effect of aminoguanidine on caspase-3 expression in rat retina after ischemia-reperfusion injury.
Reperfusion Injury
Effect of limb ischemic preconditioning on myocardial apoptosis-related proteins in ischemia-reperfusion injury.
Reperfusion Injury
Effect of Shenfu Injection (ginesenoside and aconite alkaloid) on the apoptosis of intestinal mucosal epithelial cells and its mechanism during ischemia-reperfusion in rats.
Reperfusion Injury
Effects of dexmedetomidine in conjunction with remote ischemic preconditioning on renal ischemia-reperfusion injury in rats.
Reperfusion Injury
Effects of Ganoderma lucidum Polysaccharides on Different Pathways Involved in the Development of Spinal Cord Ischemia Reperfusion Injury: Biochemical, Histopathologic, and Ultrastructural Analysis in a Rat Model.
Reperfusion Injury
Effects of isoflurane preconditioning in the delayed phase on myocardial tumor necrosis factor alpha levels and caspase-3 protein expression in a rabbit model of ischemia-reperfusion injury.
Reperfusion Injury
Effects of magnesium sulfate on neuron apoptosis and expression of caspase-3, bax and bcl-2 after cerebral ischemia-reperfusion injury.
Reperfusion Injury
Effects of memantine and galantamine given separately or in association, on memory and hippocampal neuronal loss after transient global cerebral ischemia in gerbils.
Reperfusion Injury
Exogenous surfactant attenuation of ischemia-reperfusion injury in the lung through alteration of inflammatory and apoptotic factors.
Reperfusion Injury
Ginsenoside Rb1 protects against spinal cord ischemia-reperfusion injury in rats by downregulating the Bax/Bcl-2 ratio and caspase-3 and p-Ask-1 levels.
Reperfusion Injury
Huangzhi Oral Liquid Prevents Arrhythmias by Upregulating Caspase-3 and Apoptosis Network Proteins in Myocardial Ischemia-Reperfusion Injury in Rats.
Reperfusion Injury
Identification of gene family of caspases in rat kidney and altered expression in ischemia-reperfusion injury.
Reperfusion Injury
Inhibition of Frizzled-2 by small interfering RNA protects rat hepatic BRL-3A cells against cytotoxicity and apoptosis induced by Hypoxia/Reoxygenation.
Reperfusion Injury
Is internal thoracic artery resistant to reperfusion injury? Evaluation of the storage of free internal thoracic artery grafts.
Reperfusion Injury
Liver-Wrapping, Nitric Oxide-Releasing Nanofiber Downregulates Cleaved Caspase-3 and Bax Expression on Rat Hepatic Ischemia-Reperfusion Injury.
Reperfusion Injury
MiR-484 Protects Rat Myocardial Cells from Ischemia-Reperfusion Injury by Inhibiting Caspase-3 and Caspase-9 during Apoptosis.
Reperfusion Injury
Mitochondrial K(ATP) channel opener prevents ischemia-reperfusion injury in rat liver.
Reperfusion Injury
Naked caspase 3 small interfering RNA is effective in cold preservation but not in autotransplantation of porcine kidneys.
Reperfusion Injury
Necroptotic-Apoptotic Regulation in an Endothelin-1 Model of Cerebral Ischemia.
Reperfusion Injury
Negative Regulation of TGF? Signaling by Stem Cell Antigen-1 Protects against Ischemic Acute Kidney Injury.
Reperfusion Injury
Neuroprotective effect of 20(R)-ginsenoside Rg(3) against transient focal cerebral ischemia in rats.
Reperfusion Injury
Neuroprotective effect of penehyclidine hydrochloride on focal cerebral ischemia-reperfusion injury.
Reperfusion Injury
Neuroprotective effect of small interfering RNA targeted to caspase-3 on rat retinal ganglion cell loss induced by ischemia and reperfusion injury.
Reperfusion Injury
Neuroprotective Properties of Picroside II in a Rat Model of Focal Cerebral Ischemia.
Reperfusion Injury
Non-enzymatic oxidized metabolite of DHA, 4(RS)-4-F4t-neuroprostane protects the heart against reperfusion injury.
Reperfusion Injury
Oligophrenin1 protects mice against myocardial ischemia and reperfusion injury by modulating inflammation and myocardial apoptosis.
Reperfusion Injury
Oxaloacetate protects rat liver from experimental warm ischemia-reperfusion injury by improving cellular energy metabolism.
Reperfusion Injury
PKA Inhibitor H89 (N-[2-p-bromocinnamylamino-ethyl]-5-isoquinolinesulfonamide) Attenuates Synaptic Dysfunction and Neuronal Cell Death following Ischemic Injury.
Reperfusion Injury
Platelet adhesion mediated by fibrinogen-intercelllular adhesion molecule-1 binding induces tissue injury in the postischemic liver in vivo.
Reperfusion Injury
Prevention of lung ischemia-reperfusion injury by short hairpin RNA-mediated caspase-3 gene silencing.
Reperfusion Injury
Protective Effect of Antiapoptosis Potency of Prolonged Preservation by Desiccation Using High-Pressure Carbon Monoxide on Isolated Rabbit Hearts.
Reperfusion Injury
Protective effect of sevoflurane on myocardial ischemia-reperfusion injury in rat hearts and its impact on HIF-1? and caspase-3 expression.
Reperfusion Injury
Protective effect of the traditional Chinese medicine xuesaitong on intestinal ischemia-reperfusion injury in rats.
Reperfusion Injury
Protective role of curcumin on renal ischemia reperfusion injury via attenuating the inflammatory mediators and Caspase-3.
Reperfusion Injury
Protocatechuic Acid Prevents Early Hour Ischemic Reperfusion Brain Damage by Restoring Imbalance of Neuronal Cell Death and Survival Proteins.
Reperfusion Injury
Rapamycin prevents cerebral stroke by modulating apoptosis and autophagy in penumbra in rats.
Reperfusion Injury
Remote Preconditioning on Rat Hepatic Ischemia-Reperfusion Injury Downregulated Bax and Cleaved Caspase-3 Expression.
Reperfusion Injury
Restoration of sirt1 function by pterostilbene attenuates hypoxia-reoxygenation injury in cardiomyocytes.
Reperfusion Injury
Saffron extracts alleviate cardiomyocytes injury induced by doxorubicin and ischemia-reperfusion in vitro.
Reperfusion Injury
Senkyunolide I protects rat brain against focal cerebral ischemia-reperfusion injury by up-regulating p-Erk1/2, Nrf2/HO-1 and inhibiting caspase 3.
Reperfusion Injury
Serum-stabilized Naked Caspase-3 siRNA Protects Autotransplant Kidneys in a Porcine Model.
Reperfusion Injury
Sevoflurane postconditioning prevents activation of caspase 3 and 9 through antiapoptotic signaling after myocardial ischemia-reperfusion.
Reperfusion Injury
TAT-Ngn2 Enhances Cognitive Function Recovery and Regulates Caspase-Dependent and Mitochondrial Apoptotic Pathways After Experimental Stroke.
Reperfusion Injury
The cardioprotective effect of the low molecular weight isoform of fibroblast growth factor-2: the role of JNK signaling.
Reperfusion Injury
The cytoprotective effects of addition of activated protein C into preservation solution on small-for-size grafts in rats.
Reperfusion Injury
The effects of simvastatin preconditioning on the expression of caspase-3 after myocardial ischemia reperfusion injury in rats.
Reperfusion Injury
The protective effect of low-dose methotrexate on ischemia-reperfusion injury of the rabbit spinal cord.
Reperfusion Injury
The protective effects and potential mechanism of Calpain inhibitor Calpeptin against focal cerebral ischemia-reperfusion injury in rats.
Reperfusion Injury
Upregulation of Bcl-2 through caspase-3 inhibition ameliorates ischemia/reperfusion injury in rat cardiac allografts.
Reperfusion Injury
Use of antioxidants in surgery: a measure to reduce postoperative complications.
Reperfusion Injury
[An experimental study of the therapeutical effect of bFGF in retinal ischemia/reperfusion injury]
Reperfusion Injury
[Effect and mechanism of icariin on myocardial ischemia-reperfusion injury model in diabetes rats].
Reperfusion Injury
[Effect on p53 and caspase-3 of hippocampal neuron in the rats with cerebral ischemia-reperfusion injury treated with electroacupuncture preconditioning at the acupoints on the basis of biao and ben relationship].
Reperfusion Injury
[Effects of activation of caspase-3 in cerebral ischemic reperfusion injury]
Reperfusion Injury
[Effects of caspase-3 inhibitor on the neuronal apoptosis in rat cerebral cortex after ischemia-reperfusion injury]
Reperfusion Injury
[Effects of dexmedetomidine in conjunction with remote ischemic preconditioning on renal ischemia-reperfusion injury in rats].
Reperfusion Injury
[Effects of sodium aescinate on bcl-2 and caspase-3 expression and apoptosis after focal cerebral ischemia reperfusion injury in rats]
Respiratory Distress Syndrome
Cleaved caspase-3 in lung epithelium of children with acute respiratory distress syndrome who died.
Respiratory Distress Syndrome, Newborn
Correlation of expression levels of caspase-3 and Bcl-2 in alveolar lavage fluid in neonatal respiratory distress syndrome and prognosis.
Respiratory Insufficiency
Propofol induces neuronal apoptosis in infant rat brain under hypoxic conditions.
Retinal Degeneration
Caspase-3 inhibitor reduces apototic photoreceptor cell death during inherited retinal degeneration in tubby mice.
Retinal Degeneration
Caspase-3 inhibitor rescues N -methyl- N -nitrosourea-induced retinal degeneration in Sprague-Dawley rats.
Retinal Degeneration
Caspase-3 inhibitor transiently delays inherited retinal degeneration in C3H mice carrying the rd gene.
Retinal Degeneration
Interleukin-18 induces retinal pigment epithelium degeneration in mice.
Retinal Degeneration
Light-induced photoreceptor apoptosis in vivo requires neuronal nitric-oxide synthase and guanylate cyclase activity and is caspase-3-independent.
Retinal Degeneration
Neuroprotective Effect of siRNA Entrapped in Hyaluronic Acid-Coated Lipoplexes by Intravitreal Administration.
Retinal Detachment
Inhibition of Retinal Detachment-induced Apoptosis in Photoreceptors by a Small Peptide Inhibitor of the Fas Receptor.
Retinal Detachment
XIAP effects on retinal detachment-induced photoreceptor apoptosis [corrected].
Retinal Diseases
Evidence For Multiple Cell Death Pathways During Development of Experimental Cytomegalovirus Retinitis in Mice with Retrovirus-induced Immunosuppression: Apoptosis, Necroptosis, and Pyroptosis.
Retinitis
Autophagy protects against retinal cell death in mouse model of cytomegalovirus retinitis.
Retinitis
The Role of Caspase-12 in Retinal Bystander Cell Death and Innate Immune Responses against MCMV Retinitis.
Retinitis Pigmentosa
Caspase-3 inhibitor rescues N -methyl- N -nitrosourea-induced retinal degeneration in Sprague-Dawley rats.
Retinitis Pigmentosa
Mice deficient in UXT exhibit retinitis pigmentosa-like features via aberrant autophagy activation.
Retinoblastoma
A novel cdk2-selective inhibitor, SU9516, induces apoptosis in colon carcinoma cells.
Retinoblastoma
Activation of caspase-3 and cleavage of Rb are associated with p16-mediated apoptosis in human non-small cell lung cancer cells.
Retinoblastoma
Activation of PKC but not of ERK is required for vitamin E-succinate-induced apoptosis of HL-60 cells.
Retinoblastoma
Arsenic trioxide induced apoptosis in retinoblastoma cells by abnormal expression of microRNA-376a.
Retinoblastoma
Assessing proliferation, cell-cycle arrest and apoptotic end points in human buccal punch biopsies for use as pharmacodynamic biomarkers in drug development.
Retinoblastoma
Caspase 3 deficiency rescues peripheral nervous system defect in retinoblastoma nullizygous mice.
Retinoblastoma
Combination of suberoylanilide hydroxamic acid and ritonavir is effective against renal cancer cells.
Retinoblastoma
Cyclooxygenase (COX)-2 and cell cycle activity in a transgenic mouse model of Alzheimer's disease neuropathology.
Retinoblastoma
Differential MicroRNA-34a Expression and Tumor Suppressor Function in Retinoblastoma Cells.
Retinoblastoma
Dysregulation of the cyclin-dependent kinase inhibitor p21WAF1/CIP1/MDA6 increases the susceptibility of human leukemia cells (U937) to 1-beta-D-arabinofuranosylcytosine-mediated mitochondrial dysfunction and apoptosis.
Retinoblastoma
Effect of trichostatin A, a histone deacetylase inhibitor, on glioma proliferation in vitro by inducing cell cycle arrest and apoptosis.
Retinoblastoma
Epstein-Barr virus LMP1 initiates cell proliferation and apoptosis inhibition via regulating expression of Survivin in nasopharyngeal carcinoma.
Retinoblastoma
Forced Trefoil Factor Family Peptide 3 (TFF3) Expression Reduces Growth, Viability, and Tumorigenicity of Human Retinoblastoma Cell Lines.
Retinoblastoma
Galangin inhibits the cell progression and induces cell apoptosis through activating PTEN and Caspase-3 pathways in retinoblastoma.
Retinoblastoma
Ginsenoside Rh1 Induces MCF-7 Cell Apoptosis and Autophagic Cell Death through ROS-Mediated Akt Signaling.
Retinoblastoma
Histone deacetylase inhibitors valproic acid and depsipeptide sensitize retinoblastoma cells to radiotherapy by increasing H2AX phosphorylation and p53 acetylation-phosphorylation.
Retinoblastoma
In vitro and in vivo effects and mechanisms of celecoxib-induced growth inhibition of human hepatocellular carcinoma cells.
Retinoblastoma
Inhibition of protein phosphatase-1 and -2A decreases the chemosensitivity of leukemic cells to chemotherapeutic drugs.
Retinoblastoma
Interferon-lambda induces G1 phase arrest or apoptosis in oesophageal carcinoma cells and produces anti-tumour effects in combination with anti-cancer agents.
Retinoblastoma
Involvement of caspases in apoptotic cell death of murine macrophages infected with Actinobacillus actinomycetemcomitans.
Retinoblastoma
N-Acetylcysteine enhances UV-mediated caspase-3 activation, fragmentation of E2F-4, and apoptosis in human C8161 melanoma: inhibition by ectopic Bcl-2 expression.
Retinoblastoma
Pharmacokinetics, Tissue Localization, Toxicity, and Treatment Efficacy in the First Small Animal (Rabbit) Model of Intra-Arterial Chemotherapy for Retinoblastoma.
Retinoblastoma
Ponatinib Inhibits Proliferation and Induces Apoptosis of Liver Cancer Cells, but Its Efficacy Is Compromised by Its Activation on PDK1/Akt/mTOR Signaling.
Retinoblastoma
Potential Metabolite Nymphayol Isolated from Water Lily (Nymphaea stellata) Flower Inhibits MCF-7 Human Breast Cancer Cell Growth via Upregulation of Cdkn2a, pRb2, p53 and Downregulation of PCNA mRNA Expressions.
Retinoblastoma
RbAp48 is a critical mediator controlling the transforming activity of human papillomavirus type 16 in cervical cancer.
Retinoblastoma
Reconstituted high-density lipoprotein attenuates postinfarction left ventricular remodeling in rats.
Retinoblastoma
Revisiting Old Drugs as Novel Agents for Retinoblastoma: In vitro and In vivo Antitumor Activity of Cardenolides.
Retinoblastoma
Role and potential targeting of hepatic apurinic/apyrimidinic endonuclease-1 and cyclin-dependent kinase-4 in hepatocellular carcinoma.
Retinoblastoma
Role of caspases and possible involvement of retinoblastoma protein during TGFbeta-mediated apoptosis of human B lymphocytes.
Retinoblastoma
Sodium salicylate induces apoptosis in HCT116 colorectal cancer cells through activation of p38MAPK.
Retinoblastoma
[Arsenic trioxide induced apoptosis in retinoblastoma cells in vitro and its possible mechanism]
Retinoblastoma
[GenomeLab(TM) GeXP analysis system to detect apoptosis-associated genes in A549 cells treated by recombinant human IL-24 combined with cisplatin].
Rhabdoid Tumor
The Novel Histone Deacetylase Inhibitor, OBP-801, Induces Apoptosis in Rhabdoid Tumors by Releasing the Silencing of NOXA.
Rhabdomyolysis
Class I HDAC activity is required for renal protection and regeneration after acute kidney injury.
Rhabdomyolysis
Tubular von Hippel-Lindau Knockout Protects against Rhabdomyolysis-Induced AKI.
Rhabdomyosarcoma
BMS-754807, a small molecule inhibitor of insulin-like growth factor-1R/IR.
Rhabdomyosarcoma
Enhancement of Soft Tissue Sarcoma Cell Radiosensitivity by Poly(ADP-ribose) Polymerase-1 Inhibitors.
Rheumatic Heart Disease
[Calpain-I, calpastatin, caspase-3 and apoptosis in the human left atrium in rheumatic atrial fibrillation]
Rhinitis
[Immunocytochemical detection of caspase 3 in various diseases of human nasal mucosa]
Rhinitis, Allergic
[Immunocytochemical detection of caspase 3 in various diseases of human nasal mucosa]
Rhinitis, Atrophic
[Immunocytochemical detection of caspase 3 in various diseases of human nasal mucosa]
RNA Virus Infections
A novel mitochondrial MAVS/Caspase-8 platform links RNA virus-induced innate antiviral signaling to Bax/Bak-independent apoptosis.
Sacroiliitis
Pannus inflammation in sacroiliitis following immune pathological injury and radiological structural damage: a study of 193 patients with spondyloarthritis.
Salmonella Infections
Characterization of Salmonella-induced cell death in human macrophage-like THP-1 cells.
Salmonella Infections
Salmonella typhimurium with ?-radiation induced H2AX phosphorylation and apoptosis in melanoma.
Salter-Harris Fractures
Post-traumatic caspase-3 expression in the adjacent areas of growth plate injury site: a morphological study.
Sarcoidosis
Apoptosis resistant bronchoalveolar lavage (BAL) fluid lymphocytes in sarcoidosis.
Sarcoma
Adenoviral delivery of VHL suppresses bone sarcoma cell growth through inhibition of Wnt/?-catenin signaling.
Sarcoma
Apoptosis in spermatocytic and usual seminomas: a light microscopic and immunohistochemical study.
Sarcoma
Differential Sensitivity of Taxol-induced Apoptosis in U2OS and SaOS2 Osteogenic Sarcoma Cells.
Sarcoma
Functions of microRNA-143 in the apoptosis, invasion and migration of nasopharyngeal carcinoma.
Sarcoma
High-performance liquid chromatography/nano-electrospray ionization tandem mass spectrometry, two-dimensional difference in-gel electrophoresis and gene microarray identification of lymphatic metastasis-associated biomarkers.
Sarcoma
Id3-mediated enhancement of cisplatin-induced apoptosis in a sarcoma cell line MG-63.
Sarcoma
IFN regulatory factor 8 sensitizes soft tissue sarcoma cells to death receptor-initiated apoptosis via repression of FLICE-like protein expression.
Sarcoma
In vivo effects of focused shock waves on tumor tissue visualized by fluorescence staining techniques.
Sarcoma
Intratumoral talimogene laherparepvec injection with concurrent preoperative radiation in patients with locally advanced soft-tissue sarcoma of the trunk and extremities: phase IB/II trial.
Sarcoma
Soy-Based Multiple Amino Acid Oral Supplementation Increases the Anti-Sarcoma Effect of Cyclophosphamide.
Sarcoma 180
Antitumorpharmacological mechanism of the oral liquid of Poriacocos polysaccharide.
Sarcoma 180
Hepatocyte growth factor/scatter factor activates the apoptosis signaling pathway by increasing caspase-3 activity in sarcoma 180 cells.
Sarcoma 180
Involvement of oxidative stress in tumor cytotoxic activity of hepatocyte growth factor/scatter factor.
Sarcoma, Ewing
Cell cycle inhibition and apoptosis induced by curcumin in Ewing sarcoma cell line SK-NEP-1.
Sarcoma, Ewing
Drug-induced caspase-3 activation in a Ewing tumor cell line and primary Ewing tumor cells.
Sarcoma, Ewing
EWS Knockdown and Taxifolin Treatment Induced Differentiation and Removed DNA Methylation from p53 Promoter to Promote Expression of Puma and Noxa for Apoptosis in Ewing's Sarcoma.
Sarcoma, Ewing
EWS/FLI1 oncogene activates caspase 3 transcription and triggers apoptosis in vivo.
Sarcoma, Ewing
Inhibition of SOX2 induces cell apoptosis and G1/S arrest in Ewing's sarcoma through the PI3K/Akt pathway.
Sarcoma, Ewing
miR-185 suppresses progression of Ewing's sarcoma via inhibiting the PI3K/AKT and Wnt/?-catenin pathways.
Sarcoma, Kaposi
Human bcl-2 Expression, Cleaved Caspase-3, and KSHV LANA-1 in Kaposi Sarcoma Lesions.
Sarcoma, Kaposi
Kaposi's sarcoma herpesvirus microRNAs target caspase 3 and regulate apoptosis.
Sarcoma, Kaposi
The CB1/CB2 receptor agonist WIN-55,212-2 reduces viability of human Kaposi's sarcoma cells in vitro.
Sarcoma, Kaposi
The proapoptotic protein Bim is up regulated by 1?,25-dihydroxyvitamin D3 and its receptor agonist in endothelial cells and transformed by viral GPCR associated to Kaposi sarcoma.
Schistosomiasis
Altered levels of circulating miRNAs are associated Schistosoma japonicum infection in mice.
Scleroderma, Systemic
Autoantibody against caspase-3, an executioner of apoptosis, in patients with systemic sclerosis.
Scrapie
Distinct spatial activation of intrinsic and extrinsic apoptosis pathways in natural scrapie: association with prion-related lesions.
Scrapie
Inhibition of P53-related apoptosis had no effect on PrP(Sc) accumulation and prion disease incubation time.
Seizures
2R,4R-APDC, a Metabotropic Glutamate Receptor Agonist, Reduced Neuronal Apoptosis by Upregulating MicroRNA-128 in a Rat Model After Seizures.
Seizures
A selective inhibitor of Drp1, mdivi-1, protects against cell death of hippocampal neurons in pilocarpine-induced seizures in rats.
Seizures
Activation of AKT/GSK3? pathway by TDZD-8 attenuates kainic acid induced neurodegeneration but not seizures in mice.
Seizures
Activation of the caspase 8 pathway mediates seizure-induced cell death in cultured hippocampal neurons.
Seizures
Alterations in bcl-2 and caspase gene family protein expression in human temporal lobe epilepsy.
Seizures
Antiapoptotic and neuroprotective role of Curcumin in Pentylenetetrazole (PTZ) induced kindling model in rat.
Seizures
Anticonvulsant and anti-apoptosis effects of salvianolic acid B on pentylenetetrazole-kindled rats via AKT/CREB/BDNF signaling.
Seizures
Caspase-3 is not activated in seizure-induced neuronal necrosis with internucleosomal DNA cleavage.
Seizures
Caspase-3-associated apoptotic cell death in excitotoxic necrosis of the entorhinal cortex following intraperitoneal injection of kainic acid in the rat.
Seizures
Clusterin interaction with Bcl-x(L) is associated with seizure-induced neuronal death.
Seizures
Co-induction of p75(NTR) and the associated death executor NADE in degenerating hippocampal neurons after kainate-induced seizures in the rat.
Seizures
Contribution of nitric oxide, superoxide anion, and peroxynitrite to activation of mitochondrial apoptotic signaling in hippocampal CA3 subfield following experimental temporal lobe status epilepticus.
Seizures
Cortical expression of IL1-?, Bcl-2, Caspase-3 and 9, SEMA-3a, NT-3 and P-glycoprotein as biological markers of intrinsic severity in drug-resistant temporal lobe epilepsy.
Seizures
Death mechanisms in status epilepticus-generated neurons and effects of additional seizures on their survival.
Seizures
Dynamic Pattern of Gene Expression of ZnT-4, Caspase-3, LC3, and PRG-3 in Rat Cerebral Cortex Following Flurothyl-Induced Recurrent Neonatal Seizures.
Seizures
Effects of metformin on apoptosis and ?-synuclein in a rat model of pentylenetetrazole-induced epilepsy.
Seizures
Ferulic acid ameliorates pentylenetetrazol-induced seizures by reducing neuron cell death.
Seizures
Ghrelin protects against cell death of hippocampal neurons in pilocarpine-induced seizures in rats.
Seizures
Heat shock protein 70 protects against seizure-induced neuronal cell death in the hippocampus following experimental status epilepticus via inhibition of nuclear factor-?B activation-induced nitric oxide synthase II expression.
Seizures
Intranasal nerve growth factor attenuating the seizure onset via p75R/Caspase pathway in the experimental epilepsy.
Seizures
Investigation on the Anticonvulsant Potential of Luteolin and Micronized Luteolin in Adult Zebrafish (Danio rerio).
Seizures
Involvement of caspase-3-like protease in the mechanism of cell death following focally evoked limbic seizures.
Seizures
Ketogenic diet protects the hippocampus from kainic acid toxicity by inhibiting the dissociation of bad from 14-3-3.
Seizures
Ketogenic diet reduces Smac/Diablo and cytochrome c release and attenuates neuronal death in a mouse model of limbic epilepsy.
Seizures
Methylene Blue Exerts Anticonvulsant and Neuroprotective Effects on Self-Sustaining Status Epilepticus (SSSE) Induced by Prolonged Basolateral Amygdala Stimulation in Wistar Rats.
Seizures
MicroRNA-124 and -137 cooperativity controls caspase-3 activity through BCL2L13 in hippocampal neural stem cells.
Seizures
Mild as well as severe insults produce necrotic, not apoptotic, cells: evidence from 60-min seizures.
Seizures
Mitochondrial damage in hippocampal neurons of rats with epileptic protein expression of Fas and caspase-3.
Seizures
Neuronal apoptosis in the resected sclerotic hippocampus in patients with mesial temporal lobe epilepsy.
Seizures
Neuroprotection of co-activation of GABA receptors by preventing caspase-3 denitrosylation in KA-induced seizures.
Seizures
Neuroprotective effect of vitamin C against PTZ induced apoptotic neurodegeneration in adult rat brain.
Seizures
Preservation of mitochondrial integrity and energy metabolism during experimental status epilepticus leads to neuronal apoptotic cell death in the hippocampus of the rat.
Seizures
Prolonged seizure activity causes caspase dependent cleavage and dysfunction of G-protein activated inwardly rectifying potassium channels.
Seizures
Protective effect of topiramate on kainic acid-induced cell death in mice hippocampus.
Seizures
Protein kinase Cdelta is associated with 14-3-3 phosphorylation in seizure-induced neuronal death.
Seizures
Recombinant Human Erythropoietin Protects Myocardial Cells from Apoptosis via the Janus-Activated Kinase 2/Signal Transducer and Activator of Transcription 5 Pathway in Rats with Epilepsy.
Seizures
Relationship between changes in mitochondrial function and hippocampal neuronal apoptosis after recurrent convulsion during developmental stage.
Seizures
Role of PI3K/Akt in diazoxide preconditioning against rat hippocampal neuronal death in pilocarpine-induced seizures.
Seizures
Saikosaponin a functions as anti-epileptic effect in pentylenetetrazol induced rats through inhibiting mTOR signaling pathway.
Seizures
Seizure-like activity leads to the release of BAD from 14-3-3 protein and cell death in hippocampal neurons in vitro.
Seizures
Targeting of microRNA-199a-5p protects against pilocarpine-induced status epilepticus and seizure damage via SIRT1-p53 cascade.
Seizures
The Effects of Proton Pump Inhibitors (Pantoprazole) on Pentylenetetrazole-Induced Epileptic Seizures in Rats and Neurotoxicity in the SH-SY5Y Human Neuroblastoma Cell Line.
Seizures
The effects of simvastatin on hippocampal caspase-3 and Bcl-2 expression following kainate-induced seizures in rats.
Seizures
The Effects of Topiramate on Caspase-3 Expression in Hippocampus of Basolateral Amygdala (BLA) Electrical Kindled Epilepsy Rat.
Seizures
The neuroprotective effects of heat shock protein 27 overexpression in transgenic animals against kainate-induced seizures and hippocampal cell death.
Seizures
Upregulation of nitric oxide synthase II contributes to apoptotic cell death in the hippocampal CA3 subfield via a cytochrome c/caspase-3 signaling cascade following induction of experimental temporal lobe status epilepticus in the rat.
Seminoma
Apoptosis in spermatocytic and usual seminomas: a light microscopic and immunohistochemical study.
Sepsis
Adiponectin Attenuates Lipopolysaccharide-induced Apoptosis by Regulating the Cx43/PI3K/AKT Pathway.
Sepsis
Administration of Human Protein-C concentrate prevents apoptotic brain cell death after experimental sepsis.
Sepsis
Administration of nicotinamide riboside prevents oxidative stress and organ injury in sepsis.
Sepsis
An in silico appraisal to identify high affinity anti-apoptotic synthetic tetrapeptide inhibitors targeting the mammalian caspase 3 enzyme.
Sepsis
Caspase-3 activation, Bcl-2 contents, and soluble FAS-ligand are not related to the inflammatory marker profile in patients with sepsis and septic shock.
Sepsis
Caspase-3 and -8 activation and cytokine removal with a novel cellulose triacetate super-permeable membrane in an in vitro sepsis model.
Sepsis
Caspase-3 knock-down reverses contractile dysfunction induced by sepsis in adult rat ventricular myocytes.
Sepsis
Cleaved caspase-3 expression in hypothalamic magnocellular neurons may affect vasopressin secretion during experimental polymicrobial sepsis.
Sepsis
DEFICIENCY OF BID PROTEIN REDUCES SEPSIS-INDUCED APOPTOSIS, INFLAMMATION AND IMPROVES SEPTIC SURVIVAL.
Sepsis
Dexmedetomidine-mediated protection against septic liver injury depends on TLR4/MyD88/NF-?B signaling downregulation partly via cholinergic anti-inflammatory mechanisms.
Sepsis
Distinct cardiodynamic and molecular characteristics during early and late stages of sepsis-induced myocardial dysfunction.
Sepsis
Distinct cell death markers identified in critical care patient survivors diagnosed with sepsis.
Sepsis
Effect of chemically modified tetracycline on transforming growth factor-beta1 and caspase-3 activation in liver of septic rats.
Sepsis
Effect of Glutamine on Caspase-3 mRNA and Protein Expression in the Myocardium of Rats With Sepsis.
Sepsis
Endothelin-converting enzyme-1-mediated signaling in adult rat ventricular myocyte contractility and apoptosis during sepsis.
Sepsis
Endotoxin reduces CD95-induced neutrophil apoptosis by cIAP-2-mediated caspase-3 degradation.
Sepsis
Investigation of oxidant/antioxidant and anti-inflammatory effects of apigenin on apoptosis in sepsis-induced rat lung.
Sepsis
Levosimendan attenuates multiple organ injury and improves survival in peritonitis-induced septic shock: studies in a rat model.
Sepsis
Over-expression of calpastatin inhibits calpain activation and attenuates myocardial dysfunction during endotoxaemia.
Sepsis
Protein kinase C-zeta (PKC-zeta) regulates Kupffer cell apoptosis during experimental sepsis.
Sepsis
Selective detection and inhibition of active caspase-3 in cells with optimized peptides.
Sepsis
Sepsis induces apoptosis and profound depletion of splenic interdigitating and follicular dendritic cells.
Sepsis
Sepsis stimulates calpain activity in skeletal muscle by decreasing calpastatin activity but does not activate caspase-3.
Sepsis
Serum caspase 3 levels are associated with early mortality in severe septic patients.
Sepsis
Simvastatin Protects Cardiomyocytes Against Endotoxin-induced Apoptosis and Up-regulates Survivin/NF-?B/p65 Expression.
Sepsis
Temporally Distinct Regulation of Pathways Contributing to Cardiac Proteostasis During the Acute and Recovery Phases of Sepsis.
Sepsis
The influence of early hemodynamic optimization on biomarker patterns of severe sepsis and septic shock.
Sepsis
The protective effects of angiotensin-converting enzyme inhibitor against cecal ligation and puncture-induced sepsis via oxidative stress and inflammation.
Sepsis
The role of the Hsp90/Akt pathway in myocardial calpain-induced caspase-3 activation and apoptosis during sepsis.
Sepsis
Therapeutic accessibility of caspase-mediated cell death as a key pathomechanism in indirect acute lung injury.
Sepsis
Zinc modulates the innate immune response in vivo to polymicrobial sepsis through regulation of NF-{kappa}B.
Sepsis
[Sepsis induces JNK and CHOP pathways apoptosis of lymphoid organs and stimulates inflammatory cytokines changes in the mice].
Sepsis
[Study of the mechanisms of curcumin on mitochondrial permeability transition of hepatocytes in rats with sepsis].
Sepsis
[The effect of caspase-3 inhibitor on the concentrations of serum inflammatory cytokines in sepsis related acute kidney injury induced by peritoneal cavity infection in mice.]
Sertoli Cell-Only Syndrome
Involvement of the Fas-Fas ligand system and active caspase-3 in abnormal apoptosis in human testes with maturation arrest and Sertoli cell-only syndrome.
Severe Acute Respiratory Syndrome
Severe acute respiratory syndrome coronavirus triggers apoptosis via protein kinase R but is resistant to its antiviral activity.
Shock, Septic
Activation of caspase 3 (CPP32)-like proteases is essential for TNF-alpha-induced hepatic parenchymal cell apoptosis and neutrophil-mediated necrosis in a murine endotoxin shock model.
Shock, Septic
Caspase-3 activation, Bcl-2 contents, and soluble FAS-ligand are not related to the inflammatory marker profile in patients with sepsis and septic shock.
Shock, Septic
Divergent results induced by different types of septic shock in transglutaminase 2 knockout mice.
Shock, Septic
Levosimendan attenuates multiple organ injury and improves survival in peritonitis-induced septic shock: studies in a rat model.
Shock, Septic
Sequential changes of NLRP3 inflammasome activation in sepsis and its relationship with death.
Shock, Septic
Severe Leptospirosis Features in the Spleen Indicate Cellular Immunosuppression Similar to That Found in Septic Shock.
Shock, Septic
The influence of early hemodynamic optimization on biomarker patterns of severe sepsis and septic shock.
Shock, Septic
Upregulation of programmed death-1 on T cells and programmed death ligand-1 on monocytes in septic shock patients.
Shock, Septic
Upregulation of the pro-apoptotic genes BID and FAS in septic shock patients.
Shock, Septic
[Protective effect of low-dose hydrocortisone on myocardium in early septic shock].
Sialadenitis
Epigallocatechin gallate inhibits oxidative stress-induced DNA damage and apoptosis in MRL-Fas(lpr) mice with autoimmune sialadenitis via upregulation of heme oxygenase-1 and Bcl-2.
Silicosis
Ac-SDKP increases ?-TAT 1 and promotes the apoptosis in lung fibroblasts and epithelial cells double-stimulated with TGF-?1 and silica.
Silicosis
Fas/FasL pathway-mediated alveolar macrophage apoptosis involved in human silicosis.
Silicosis
Granuloma formation induced by low-dose chronic silica inhalation is associated with an anti-apoptotic response in Lewis rats.
Sinusitis
[Protective effects of minocycline against apoptosis of olfactory sensory neurons]
Skin Neoplasms
c-Jun N-terminal kinase 1 phosphorylates Myt1 to prevent UVA-induced skin cancer.
Skin Neoplasms
Fucose-containing sulfated polysaccharides from brown seaweeds inhibit proliferation of melanoma cells and induce apoptosis by activation of caspase-3 in vitro.
Skin Neoplasms
Salidroside prevents skin carcinogenesis induced by DMBA/TPA in a mouse model through suppression of inflammation and promotion of apoptosis.
Sleep Apnea Syndromes
Simulating sleep apnea by exposure to intermittent hypoxia induces inflammation in the lung and liver.
Sleep Deprivation
Sleep deprivation aggravates brain injury after experimental subarachnoid hemorrhage via TLR4-MyD88 pathway.
Sleep Initiation and Maintenance Disorders
Expression of excitatory amino acid transporter-1 (EAAT-1) in brain macrophages and microglia of patients with prion diseases.
Small Cell Lung Carcinoma
Caspase-3 activation is not responsible for vinblastine-induced Bcl-2 phosphorylation and G2/M arrest in human small cell lung carcinoma Ms-1 cells.
Small Cell Lung Carcinoma
Inhibition of fibroblast growth factor 2-induced apoptosis involves survivin expression, protein kinase C alpha activation and subcellular translocation of Smac in human small cell lung cancer cells.
Spastic Paraplegia, Hereditary
Spastic paraplegia, ataxia, mental retardation (SPAR): a novel genetic disorder.
Spermatic Cord Torsion
Rapamycin protects testes against germ cell apoptosis and oxidative stress induced by testicular ischemia-reperfusion.
Sphingolipidoses
Apoptosis of Neuro2a cells induced by lysosphingolipids with naturally occurring stereochemical configurations.
Spina Bifida Cystica
Correlation between spina bifida manifesta in fetal rats and c-Jun N-terminal kinase signaling.
Spinal Cord Compression
Apoptosis in human compressive myelopathy due to metastatic neoplasia.
Spinal Cord Compression
Expression of apoptosis signal-regulating kinase 1 in mouse spinal cord under chronic mechanical compression: possible involvement of the stress-activated mitogen-activated protein kinase pathways in spinal cord cell apoptosis.
Spinal Cord Diseases
Expression of AIF and Caspase-3 in New Zealand rabbit with Cervical Spondylosis Myelopathy model.
Spinal Cord Injuries
A mapping study of caspase-3 activation following acute spinal cord contusion in rats.
Spinal Cord Injuries
Activation of the caspase-3 apoptotic cascade in traumatic spinal cord injury.
Spinal Cord Injuries
Anti-inflammatory and anti-apoptotic effect of combined treatment with methylprednisolone and amniotic membrane mesenchymal stem cells after spinal cord injury in rats.
Spinal Cord Injuries
Asiaticoside Inhibits Neuronal Apoptosis and Promotes Functional Recovery After Spinal Cord Injury in Rats.
Spinal Cord Injuries
Calcineurin-mediated BAD dephosphorylation activates the caspase-3 apoptotic cascade in traumatic spinal cord injury.
Spinal Cord Injuries
Caspase-3 activity is reduced after spinal cord injury in mice lacking dynorphin: Differential effects on glia and neurons.
Spinal Cord Injuries
Combined Administration of Poly-ADP-Ribose Polymerase-1 and Caspase-3 Inhibitors Alleviates Neuronal Apoptosis After Spinal Cord Injury in Rats.
Spinal Cord Injuries
Effect of methylprednisolone on the activities of caspase-3, -6, -8 and -9 in rabbits with acute spinal cord injury.
Spinal Cord Injuries
Effects of gangliosides on expressions of caspase-3 and NGF in rats with acute spinal cord injury.
Spinal Cord Injuries
Expression and effect of Caspase-3 in neurons after tractive spinal cord injury in rats.
Spinal Cord Injuries
FK506 treatment inhibits caspase-3 activation and promotes oligodendroglial survival following traumatic spinal cord injury.
Spinal Cord Injuries
Functional role and therapeutic implications of neuronal caspase-1 and -3 in a mouse model of traumatic spinal cord injury.
Spinal Cord Injuries
IL-1 receptor antagonist prevents apoptosis and caspase-3 activation after spinal cord injury.
Spinal Cord Injuries
Impacts of Bone Marrow Stem Cells on Caspase-3 Levels after Spinal Cord Injury in Mice.
Spinal Cord Injuries
Increased production of reactive oxygen species contributes to motor neuron death in a compression mouse model of spinal cord injury.
Spinal Cord Injuries
Magnesium sulfate treatment decreases caspase-3 activity after experimental spinal cord injury in rats.
Spinal Cord Injuries
Mechanisms underlying the promotion of functional recovery by deferoxamine after spinal cord injury in rats.
Spinal Cord Injuries
Mexiletine treatment-induced inhibition of caspase-3 activation and improvement of behavioral recovery after spinal cord injury.
Spinal Cord Injuries
Montelukast inhibits caspase-3 activity and ameliorates oxidative damage in the spinal cord and urinary bladder of rats with spinal cord injury.
Spinal Cord Injuries
Neurocyte apoptosis and expressions of caspase-3 and Fas after spinal cord injury and their implication in rats.
Spinal Cord Injuries
Neuroprotection of netrin-1 on neurological recovery via Wnt/?-catenin signaling pathway after spinal cord injury.
Spinal Cord Injuries
Neuroprotective effects of caspase-3 inhibition on functional recovery and tissue sparing after acute spinal cord injury.
Spinal Cord Injuries
Neuroprotective effects of Ganoderma lucidum polysaccharides against traumatic spinal cord injury in rats.
Spinal Cord Injuries
Neuroprotective effects of rapamycin on spinal cord injury in rats by increasing autophagy and Akt signaling.
Spinal Cord Injuries
Neuroprotective effects of rosuvastatin against traumatic spinal cord injury in rats.
Spinal Cord Injuries
Neuroprotective effects of sildenafil in experimental spinal cord injury in rabbits.
Spinal Cord Injuries
Nitric oxide and cell signaling: in vivo evaluation of NO-dependent apoptosis by MRI and not NMR techniques.
Spinal Cord Injuries
Preventive effect of erythropoietin on spinal cord cell apoptosis following acute traumatic injury in rats.
Spinal Cord Injuries
Rapid upregulation of caspase-3 in rat spinal cord after injury: mRNA, protein, and cellular localization correlates with apoptotic cell death.
Spinal Cord Injuries
Recombinant human erythropoietin decreases myeloperoxidase and caspase-3 activity and improves early functional results after spinal cord injury in rats.
Spinal Cord Injuries
Spatiotemporal expression of EAPP modulates neuronal apoptosis and reactive astrogliosis after spinal cord injury.
Spinal Cord Injuries
The Effect of Methylprednisolone on Caspase-3 Activation after Rat Spinal Cord Transection.
Spinal Cord Injuries
The neuroprotective effects of z-DEVD.fmk, a caspase-3 inhibitor, on traumatic spinal cord injury in rats.
Spinal Cord Injuries
Therapeutic efficacy of Ac-DMQD-CHO, a caspase 3 inhibitor, for rat spinal cord injury.
Spinal Cord Injuries
Time representation of mitochondrial morphology and function after acute spinal cord injury.
Spinal Cord Injuries
Time-dependent changes in caspase-3 activity and heat shock protein 25 after spinal cord transection in adult rats.
Spinal Cord Injuries
Transplantation of erythropoietin gene-modified neural stem cells improves the repair of injured spinal cord.
Spinal Cord Injuries
Trehalose protects against spinal cord injury through regulating heat shock proteins 27 and 70 and caspase-3 genes expression.
Spinal Cord Injuries
Tumor Necrosis Factor-Alpha Antagonist Reduces Apoptosis of Neurons and Oligodendroglia in Rat Spinal Cord Injury.
Spinal Cord Injuries
[Effect of basic fibroblast growth factor on change of caspase 3 gene expression after distractive spinal cord injury in rats]
Spinal Cord Injuries
[Effect of electroacupuncture with different frequencies on hindlimb locomotor function and expression of LC3, Beclin 1 and cleaved Caspase-3 proteins in spinal cord injury rats].
Spinal Cord Injuries
[Effects of curcumin on the recovery of hind limb function after spinal cord injury in rats and its mechamism].
Spinal Cord Injuries
[Protective effect of transplantation of bone mesenchymal stem cells on demyelination in spinal cord injury].
Spinal Cord Injuries
[Tetramethylpyrazine accelerated spinal cord repair through regulation of caspase-3 and neurofilament protein expression: an acute spinal cord injury model in rats]
Spinal Dysraphism
Therapeutic potential of adenovirus-encoding brain-derived neurotrophic factor for spina bifida aperta by intra-amniotic delivery in a rat model.
Spinocerebellar Ataxias
Damage to the reticulotegmental nucleus of the pons in spinocerebellar ataxia type 1, 2, and 3.
Spinocerebellar Ataxias
Ocular motility in genetically defined autosomal dominant cerebellar ataxia.
Spinocerebellar Ataxias
Similarities between spinocerebellar ataxia type 7 (SCA7) cell models and human brain: proteins recruited in inclusions and activation of caspase-3.
Spondylosis
Expression of AIF and Caspase-3 in New Zealand rabbit with Cervical Spondylosis Myelopathy model.
Spondylosis
[Effects of Acupotomy Therapy on mRNA Expressions of Bcl-2, Bax, Caspase-3 in Posterior Cervical Extensor Muscles in Cervical Spondylosis Rabbits].
Squamous Cell Carcinoma of Head and Neck
A novel curcumin analog (h-4073) enhances the therapeutic efficacy of Cisplatin treatment in head and neck cancer.
Squamous Cell Carcinoma of Head and Neck
A role of sphingosine kinase 1 in head and neck carcinogenesis.
Squamous Cell Carcinoma of Head and Neck
Acacetin-induced cell apoptosis in head and neck squamous cell carcinoma cells: Evidence for the role of muscarinic M3 receptor.
Squamous Cell Carcinoma of Head and Neck
An in vivo evaluation of docetaxel delivered intratumorally in head and neck squamous cell carcinoma.
Squamous Cell Carcinoma of Head and Neck
Apigenin induces apoptosis and impairs head and neck carcinomas EGFR/ErbB2 signaling.
Squamous Cell Carcinoma of Head and Neck
Areca nut extract demonstrated apoptosis-inducing mechanism by increased caspase-3 activities on oral squamous cell carcinoma.
Squamous Cell Carcinoma of Head and Neck
Butyrate response factor 1 enhances cisplatin sensitivity in human head and neck squamous cell carcinoma cell lines.
Squamous Cell Carcinoma of Head and Neck
CASP9 c.-1339A>G and CASP3 c.-1191A>G polymorphisms alter susceptibility and clinical aspects of head and neck squamous cell carcinoma.
Squamous Cell Carcinoma of Head and Neck
Caspase-3 expression in normal oral epithelium, oral submucous fibrosis and oral squamous cell carcinoma.
Squamous Cell Carcinoma of Head and Neck
Caspase-3 expression is reduced, in the absence of cleavage, in terminally differentiated normal oral epithelium but is increased in oral squamous cell carcinomas and correlates with tumour stage.
Squamous Cell Carcinoma of Head and Neck
Chios Mastic Gum Extracts as a Potent Antitumor Agent that Inhibits Growth and Induces Apoptosis of Oral Cancer Cells.
Squamous Cell Carcinoma of Head and Neck
Cisplatin inhibits the expression of X-chromosome-linked inhibitor of apoptosis protein in an oral carcinoma cell line.
Squamous Cell Carcinoma of Head and Neck
Cytotoxic Components Against Human Oral Squamous Cell Carcinoma Isolated from Andrographis paniculata.
Squamous Cell Carcinoma of Head and Neck
Effect of photodynamic therapy on expression of HRAS, NRAS and caspase 3 genes at mRNA levels, apoptosis of head and neck squamous cell carcinoma cell line.
Squamous Cell Carcinoma of Head and Neck
Effects of Knockdown of XPO5 by siRNA on the Biological Behavior of Head and Neck Cancer Cells.
Squamous Cell Carcinoma of Head and Neck
Evaluation of p53, Caspase-3, Bcl-2, and Ki-67 markers in oral squamous cell carcinoma and premalignant epithelium in a sample from Alava Province (Spain).
Squamous Cell Carcinoma of Head and Neck
Expression levels of cleaved caspase-3 and caspase-3 in tumorigenesis and prognosis of oral tongue squamous cell carcinoma.
Squamous Cell Carcinoma of Head and Neck
Expression of survivin and caspase 3 in oral squamous cell carcinoma and peritumoral tissue.
Squamous Cell Carcinoma of Head and Neck
FAS and FASL variations in outcomes of tobacco- and alcohol-related head and neck squamous cell carcinoma patients.
Squamous Cell Carcinoma of Head and Neck
Fumonisin B1 Inhibits Endoplasmic Reticulum Stress Associated-apoptosis After FoscanPDT Combined with C6-Pyridinium Ceramide or Fenretinide.
Squamous Cell Carcinoma of Head and Neck
Galangin inhibits growth of human head and neck squamous carcinoma cells in vitro and in vivo.
Squamous Cell Carcinoma of Head and Neck
Garlic ((Allium sativum)) Fresh Juice Induces Apoptosis in Human Oral Squamous Cell Carcinoma: The Involvement of Caspase-3, Bax and Bcl-2.
Squamous Cell Carcinoma of Head and Neck
GSTP1 c.313A>G, XPD c.934G>A, XPF c.2505T>C and CASP9 c.-1339A>G Polymorphisms and Severity of Vomiting in Head and Neck Cancer Patients treated with Cisplatin Chemoradiation.
Squamous Cell Carcinoma of Head and Neck
Histone deacetylase inhibitor suberoylanilide hydroxamic acid induces apoptosis through both mitochondrial and Fas (Cd95) signaling in head and neck squamous carcinoma cells.
Squamous Cell Carcinoma of Head and Neck
Influence of CASP9 c.-1339A>G and CASP3 c.-1191A>G variants in outcome of patients with head and neck squamous cell carcinoma.
Squamous Cell Carcinoma of Head and Neck
Interleukin-1beta and Caspase-3 expression serve as independent prognostic markers for metastasis and survival in oral squamous cell carcinoma.
Squamous Cell Carcinoma of Head and Neck
Inverse correlation of apoptotic and angiogenic markers in squamous cell carcinoma of the head and neck.
Squamous Cell Carcinoma of Head and Neck
Knockdown of ?-catenin controls both apoptotic and autophagic cell death through LKB1/AMPK signaling in head and neck squamous cell carcinoma cell lines.
Squamous Cell Carcinoma of Head and Neck
Leptin acts on neoplastic behavior and expression levels of genes related to hypoxia, angiogenesis, and invasiveness in oral squamous cell carcinoma.
Squamous Cell Carcinoma of Head and Neck
Novel C-Terminal Hsp90 Inhibitor for Head and Neck Squamous Cell Cancer (HNSCC) with in vivo Efficacy and Improved Toxicity Profiles Compared with Standard Agents.
Squamous Cell Carcinoma of Head and Neck
Oral Squamous Cell Carcinoma From Users and Nonusers of Tobacco and Alcohol: Clinicopathologic Features and Immunoreactivity of VEGF, Caspase-3, and P53.
Squamous Cell Carcinoma of Head and Neck
PARP1 and CASP3 gene expression in a patient with multiple head and neck squamous cell carcinoma and Parkinson disease.
Squamous Cell Carcinoma of Head and Neck
Repression of caspase-3 and RNA-binding protein HuR cleavage by cyclooxygenase-2 promotes drug resistance in oral squamous cell carcinoma.
Squamous Cell Carcinoma of Head and Neck
Sam68 reduces cisplatin-induced apoptosis in tongue carcinoma.
Squamous Cell Carcinoma of Head and Neck
The inhibitory effect of a novel organoselenium compound BBSKE on the tongue cancer Tca8113 in vitro and in vivo.
Squamous Cell Carcinoma of Head and Neck
The primary growth of laryngeal squamous cell carcinoma cells in vitro is effectively supported by paired cancer-associated fibroblasts alone.
Squamous Cell Carcinoma of Head and Neck
The proteasome inhibitor MG132 potentiates TRAIL receptor agonist-induced apoptosis by stabilizing tBid and Bik in human head and neck squamous cell carcinoma cells.
Squamous Cell Carcinoma of Head and Neck
The sensitivity of head and neck carcinoma cells to statins is related to the expression of their Ras expression status, and statin-induced apoptosis is mediated via suppression of the Ras/ERK and Ras/mTOR pathways.
Squamous Cell Carcinoma of Head and Neck
The upregulated ?-catulin expression was involved in head-neck squamous cell carcinogenesis by promoting proliferation, migration, invasion, and epithelial to mesenchymal transition.
Squamous Cell Carcinoma of Head and Neck
Three apoptotic genes are upregulated in a patient with Alzheimer's disease and well-differentiated squamous cell carcinoma.
Squamous Cell Carcinoma of Head and Neck
[Effects of salinomycin on proliferation and apoptosis of oral squamous cell carcinoma].
Squamous Cell Carcinoma of Head and Neck
[Expression and significance of PTEN and caspase-3 in laryngeal squamous cell carcinoma]
Squamous Cell Carcinoma of Head and Neck
[Expression of Survivin, Caspase-3 and p53 in surgical margin of laryngeal squamous cell carcinoma and their relationship]
Squamous Cell Carcinoma of Head and Neck
[Expression of survivin, caspase-3 in oral precancerous lesions and oral squamous-cell carcinoma.]
Squamous Cell Carcinoma of Head and Neck
[The expression of caspase-3, bFGF and MVD in laryngeal squamous cell carcinoma and the relationship among them].
Starvation
A Protein Kinase C{epsilon}-Anti-apoptotic Kinase Signaling Complex Protects Human Vascular Endothelial Cells against Apoptosis through Induction of Bcl-2.
Starvation
Amino acid starvation induced autophagic cell death in PC-12 cells: evidence for activation of caspase-3 but not calpain-1.
Starvation
Apoptotic functions of PDCD10/CCM3, the gene mutated in cerebral cavernous malformation 3.
Starvation
Autophagy activation is required for homocysteine-induced apoptosis in bovine aorta endothelial cells.
Starvation
Bone morphogenetic protein 6 inhibit stress-induced breast cancer cells apoptosis via both Smad and p38 pathways.
Starvation
Canavanine augments proapoptotic effects of arginine deprivation in cultured human cancer cells.
Starvation
Cell death induced by serum deprivation in luteal cells involves the intrinsic pathway of apoptosis.
Starvation
Cellular repressor of E1A-stimulated genes inhibits human vascular smooth muscle cell apoptosis via blocking P38/JNK MAP kinase activation.
Starvation
Cleavage of poly (ADP-ribose) polymerase-1 is involved in the process of porcine ovarian follicular atresia.
Starvation
Depletion of p18/LAMTOR1 promotes cell survival via activation of p27(kip1) -dependent autophagy under starvation.
Starvation
DHEA protects mitochondria against dual modes of apoptosis and necroptosis in human granulosa HO23 cells.
Starvation
Different signaling pathways are involved in cardiomyocyte survival induced by a Trypanosoma cruzi glycoprotein.
Starvation
Down-regulation of hypoxia-inducible factor-1 suppresses malignant biological behavior of triple-negative breast cancer cells.
Starvation
Dual role of JNK1-mediated phosphorylation of Bcl-2 in autophagy and apoptosis regulation.
Starvation
Effect of carbonic anhydrase-related protein VIII expression on lung adenocarcinoma cell growth.
Starvation
Fasting cycles retard growth of tumors and sensitize a range of cancer cell types to chemotherapy.
Starvation
Formation of noncanonical high molecular weight caspase-3 and -6 complexes and activation of caspase-12 during serum starvation induced apoptosis in AKR-2B mouse fibroblasts.
Starvation
Global identification of genes related to nutrient deficiency in intervertebral disc cells in an experimental nutrient deprivation model.
Starvation
Glucose starvation induces apoptosis in a model of acute T leukemia dependent on caspase-3 and apoptosis-inducing factor: a therapeutic strategy.
Starvation
Growth hormone-releasing hormone promotes survival of cardiac myocytes in vitro and protects against ischaemia-reperfusion injury in rat heart.
Starvation
H2O2 treatment or serum deprivation induces autophagy and apoptosis in naked mole-rat skin fibroblasts by inhibiting the PI3K/Akt signaling pathway.
Starvation
Hepatitis B virus X protein reduces starvation-induced cell death through activation of autophagy and inhibition of mitochondrial apoptotic pathway.
Starvation
Human cytomegalovirus immediate early protein 2 enhances myocardin-mediated survival of rat aortic smooth muscle cells.
Starvation
IGF-I but not insulin inhibits apoptosis at a low concentration in vascular smooth muscle cells.
Starvation
Impact of targeting the adenine- and uracil-rich element of bcl-2 mRNA with oligoribonucleotides on apoptosis, cell cycle, and neuronal differentiation in SHSY-5Y cells.
Starvation
Increased resistance of lipofuscin-loaded prematurely senescent fibroblasts to starvation-induced programmed cell death.
Starvation
Inhibition of fibroblast growth factor 2-induced apoptosis involves survivin expression, protein kinase C alpha activation and subcellular translocation of Smac in human small cell lung cancer cells.
Starvation
Inhibition of neuronal apoptosis by docosahexaenoic acid (22:6n-3). Role of phosphatidylserine in antiapoptotic effect.
Starvation
Inhibition of Rho-associated protein kinase improves the survival of human induced pluripotent stem cell-derived cardiomyocytes after dissociation.
Starvation
Insulin can block apoptosis by decreasing oxidative stress via phosphatidylinositol 3-kinase- and extracellular signal-regulated protein kinase-dependent signaling pathways in HepG2 cells.
Starvation
Involvement of G proteins of the Rho family in the regulation of Bcl-2-like protein expression and caspase 3 activation by Gastrins.
Starvation
Ischemic Conditions Affect Rerouting of Tau Protein Levels: Evidences for Alteration in Tau Processing and Secretion in Hippocampal Neurons.
Starvation
Jurkat cells respond to biotin deficiency with increased nuclear translocation of NF-kappaB, mediating cell survival.
Starvation
Knockdown of ERp44 leads to apoptosis via activation of ER stress in HeLa cells.
Starvation
Knockdown of transmembrane protein 132A by RNA interference facilitates serum starvation-induced cell death in Neuro2a cells.
Starvation
MIR145-3p promotes autophagy and enhances bortezomib sensitivity in multiple myeloma by targeting HDAC4.
Starvation
Modeling the response of a tumor-suppressive network to mitogenic and oncogenic signals.
Starvation
Neuropeptide Y enhances proliferation and prevents apoptosis in rat bone marrow stromal cells in association with activation of the Wnt/?-catenin pathway in vitro.
Starvation
Nicorandil inhibits serum starvation-induced apoptosis in vascular endothelial cells.
Starvation
Nuclear morphology and c-Jun N-Terminal Kinase 1 expression differentiate serum starved oxidative stress signaling from hydrogen peroxide induced apoptosis in retinal neuronal cell line.
Starvation
Nutrient starvation induces apoptosis and autophagy in C6 glioma stem-like cells.
Starvation
Oxidative stress is not required for the induction of apoptosis upon glutamine starvation of Sp2/0-Ag14 hybridoma cells.
Starvation
p38 MAPK inhibition is critically involved in VEGFR-2-mediated endothelial cell survival.
Starvation
PAR2-dependent activation of GSK3? regulates the survival of colon stem/progenitor cells.
Starvation
PI3K/Akt and MAPK pathways evoke activation of FoxO transcription factor to undergo neuronal apoptosis in brain of the silkworm Bombyx mori (Lepidoptera: Bombycidae).
Starvation
Poly C binding protein 1 represses autophagy through downregulation of LC3B to promote tumor cell apoptosis in starvation.
Starvation
Progesterone production requires activation of caspase-3 in preovulatory granulosa cells in a serum starvation model.
Starvation
Repulsive guidance molecule B (RGMB) plays negative roles in breast cancer by coordinating BMP signaling.
Starvation
TGFbeta protects mesoangioblasts from apoptosis via sphingosine kinase-1 regulation.
Starvation
The effect of transforming growth factor ?1 on the crosstalk between autophagy and apoptosis in the annulus fibrosus cells under serum deprivation.
Starvation
The peroxynitrite donor 3-morpholinosydnonimine activates Nrf2 and the UPR leading to a cytoprotective response in endothelial cells.
Starvation
Thyroid hormones T3 and T4 regulate human luteinized granulosa cells, counteracting apoptosis and promoting cell survival.
Starvation
[Functional state of a sphingomyeline cycle and free radical lipid oxidation activity of a rat's liver during different phases of starvation].
Status Epilepticus
Administration of caspase 3 inhibitor during and after status epilepticus in rat: effect on neuronal damage and epileptogenesis.
Status Epilepticus
Alterations in the expression of the anti-apoptotic factor HAX-1 upon seizures-induced hippocampal injury in the neonatal rat brain.
Status Epilepticus
Caspase inhibitors increase short-term survival of progenitor-cell progeny in the adult rat dentate gyrus following status epilepticus.
Status Epilepticus
Caspase-3 is not activated in seizure-induced neuronal necrosis with internucleosomal DNA cleavage.
Status Epilepticus
Changes in sphingomyelinases, ceramide, Bax, Bcl(2), and caspase-3 during and after experimental status epilepticus.
Status Epilepticus
Characterization of cell proliferation in the adult dentate under normal conditions and after kainate induced seizures using ribonucleotide reductase and BrdU.
Status Epilepticus
Differential Roles of Mitochondrial Translocation of Active Caspase-3 and HMGB1 in Neuronal Death Induced by Status Epilepticus.
Status Epilepticus
Distinct caspase pathways mediate necrosis and apoptosis in subpopulations of hippocampal neurons after status epilepticus.
Status Epilepticus
Exclusive Activation of Caspase-3 in Mossy Fibers and Altered Dynamics of Autophagy Markers in the Mice Hippocampus upon Status Epilepticus Induced by Kainic Acid.
Status Epilepticus
Expression and activation of caspase 3 following status epilepticus in the rat.
Status Epilepticus
Expression time course and spatial distribution of activated caspase-3 after experimental status epilepticus: contribution of delayed neuronal cell death to seizure-induced neuronal injury.
Status Epilepticus
Heat shock protein 70 protects against seizure-induced neuronal cell death in the hippocampus following experimental status epilepticus via inhibition of nuclear factor-?B activation-induced nitric oxide synthase II expression.
Status Epilepticus
Inhibiting HIF-1? Decreases Expression of TNF-? and Caspase-3 in Specific Brain Regions Exposed Kainic Acid-Induced Status Epilepticus.
Status Epilepticus
Intracerebral injection of caspase-3 inhibitor prevents neuronal apoptosis after kainic acid-evoked status epilepticus.
Status Epilepticus
LONP1 Regulates Mitochondrial Accumulations of HMGB1 and Caspase-3 in CA1 and PV Neurons Following Status Epilepticus.
Status Epilepticus
Oxidative stress mediates hippocampal neuron death in rats after lithium-pilocarpine-induced status epilepticus.
Status Epilepticus
Potential neuroprotective effect of gamma-glutamylcysteine ethyl ester on rat brain against kainic acid-induced excitotoxicity.
Status Epilepticus
Protective effects of quercetin against status epilepticus induced hippocampal neuronal injury in rats: involvement of X-linked inhibitor of apoptosis protein.
Status Epilepticus
Resveratrol Promotes Mitochondrial Biogenesis and Protects against Seizure-Induced Neuronal Cell Damage in the Hippocampus Following Status Epilepticus by Activation of the PGC-1? Signaling Pathway.
Status Epilepticus
Status epilepticus leads to the degradation of the endogenous inhibitor of caspase-activated DNase in rats.
Status Epilepticus
Status epilepticus triggers caspase-3 activation and necrosis in the immature rat brain.
Status Epilepticus
Translocation of the serine protease Omi/HtrA2 from mitochondria into the cytosol upon seizure-induced hippocampal injury in the neonatal rat brain.
Status Epilepticus
Tualang Honey Reduced Neuroinflammation and Caspase-3 Activity in Rat Brain after Kainic Acid-Induced Status Epilepticus.
Status Epilepticus
Upregulation of nitric oxide synthase II contributes to apoptotic cell death in the hippocampal CA3 subfield via a cytochrome c/caspase-3 signaling cascade following induction of experimental temporal lobe status epilepticus in the rat.
Status Epilepticus
[Age difference of the activation of apoptotic cascade reaction following LiCl-pilocarpine status epilepticus]
Stomach Neoplasms
(S)-Erypoegin K, an isoflavone isolated from Erythrina poeppigiana, is a novel inhibitor of topoisomerase II?: Induction of G2 phase arrest in human gastric cancer cells.
Stomach Neoplasms
?-Carotene-induced apoptosis is mediated with loss of Ku proteins in gastric cancer AGS cells.
Stomach Neoplasms
?-elemene enhances the radiosensitivity of gastric cancer cells by inhibiting Pak1 activation.
Stomach Neoplasms
A forskolin derivative, FSK88, induces apoptosis in human gastric cancer BGC823 cells through caspase activation involving regulation of Bcl-2 family gene expression, dissipation of mitochondrial membrane potential and cytochrome c release.
Stomach Neoplasms
A novel plant homeodomain finger 10-mediated antiapoptotic mechanism involving repression of caspase-3 in gastric cancer cells.
Stomach Neoplasms
AA-PMe, a novel asiatic acid derivative, induces apoptosis and suppresses proliferation, migration, and invasion of gastric cancer cells.
Stomach Neoplasms
Adenovirus-directed expression of TIPE2 suppresses gastric cancer growth via induction of apoptosis and inhibition of AKT and ERK1/2 signaling.
Stomach Neoplasms
Akt signaling is associated with the berberine-induced apoptosis of human gastric cancer cells.
Stomach Neoplasms
Alisma canaliculatum Extract Affects AGS Gastric Cancer Cells by Inducing Apoptosis.
Stomach Neoplasms
Allitridi induces apoptosis by affecting Bcl-2 expression and caspase-3 activity in human gastric cancer cells.
Stomach Neoplasms
Anti-tumor mechanism of IL-21 used alone and in combination with 5-fluorouracil in vitro on human gastric cancer cells.
Stomach Neoplasms
Antitumor activity of ginsenoside Rd in gastric cancer via up-regulation of Caspase-3 and Caspase-9.
Stomach Neoplasms
ApoG2 as the most potent gossypol derivatives inhibits cell growth and induces apoptosis on gastric cancer cells.
Stomach Neoplasms
Apoptosis-inducing effect of recombinant Caspase-3 expressed by constructed eukaryotic vector on gastric cancer cell line SGC7901.
Stomach Neoplasms
Arsenic trioxide induces apoptosis in human gastric cancer cells through up-regulation of p53 and activation of caspase-3.
Stomach Neoplasms
Baicalin extracted from Huangqin (Radix Scutellariae Baicalensis) induces apoptosis in gastric cancer cells by regulating B cell lymphoma
(Bcl-2)/Bcl-2-associated X protein and activating caspase-3 and caspase-9.
Stomach Neoplasms
Caspase-3 expression in human gastric carcinoma and its clinical significance.
Stomach Neoplasms
Caspase-3, a key apoptotic protein, as a prognostic marker in gastric cancer after curative surgery.
Stomach Neoplasms
Caspase-4 activation in association with decreased adenosine deaminase activity may be a factor for gastric ulcer.
Stomach Neoplasms
CDH17 is a downstream effector of HOXA13 in modulating the Wnt/?-catenin signaling pathway in gastric cancer.
Stomach Neoplasms
Cell death triggered by alpha-emitting 213Bi-immunoconjugates in HSC45-M2 gastric cancer cells is different from apoptotic cell death.
Stomach Neoplasms
Chemopreventive Activity of MGN-3/Biobran Against Chemical Induction of Glandular Stomach Carcinogenesis in Rats and Its Apoptotic Effect in Gastric Cancer Cells.
Stomach Neoplasms
Citrus Reticulata blanco induces apoptosis in human gastric cancer cells SNU-668.
Stomach Neoplasms
Clinicopathological and prognostic significance of Ki-67, caspase-3 and p53 expression in gastric carcinomas.
Stomach Neoplasms
CPP32 expression and its significance in multidrug-resistant tumor cells and their parent cells.
Stomach Neoplasms
Curcumin inhibits the lymphangiogenesis of gastric cancer cells by inhibiton of HMGB1/VEGF-D signaling.
Stomach Neoplasms
Curcumin suppresses gastric cancer by inhibiting gastrin-mediated acid secretion.
Stomach Neoplasms
Defects at the Posttranscriptional Level Account for the Low TCR? Chain Expression Detected in Gastric Cancer Independently of Caspase-3 Activity.
Stomach Neoplasms
Depletion of death-associated protein-3 induces chemoresistance in gastric cancer cells through the ?-catenin/LGR5/Bcl-2 axis.
Stomach Neoplasms
Deubiquitinylase USP47 Promotes RelA Phosphorylation and Survival in Gastric Cancer Cells.
Stomach Neoplasms
Differential caspase-3 expression in noncancerous, premalignant and cancer tissues of stomach and its clinical implication.
Stomach Neoplasms
Downregulation of AKT and MDM2, Melatonin Induces Apoptosis in AGS and MGC803 Cells.
Stomach Neoplasms
Downregulation of XIAP expression induces apoptosis and enhances chemotherapeutic sensitivity in human gastric cancer cells.
Stomach Neoplasms
Elevated caspase-3 activity in peripheral blood T cells coexists with increased degree of T-cell apoptosis and down-regulation of TCR zeta molecules in patients with gastric cancer.
Stomach Neoplasms
Elevated cleaved caspase-3 is associated with shortened overall survival in several cancer types.
Stomach Neoplasms
Enhanced induction of apoptosis by combined treatment of human carcinoma cells with X rays and death receptor agonists.
Stomach Neoplasms
Enhancement of chemotherapeutic agents induced-apoptosis associated with activation of c-Jun N-terminal kinase 1 and caspase 3 (CPP32) in bax-transfected gastric cancer cells.
Stomach Neoplasms
Esculetin exerts antitumor effect on human gastric cancer cells through IGF-1/PI3K/Akt signaling pathway.
Stomach Neoplasms
Esculetin induces apoptosis in human gastric cancer cells through a cyclophilin D-mediated mitochondrial permeability transition pore associated with ROS.
Stomach Neoplasms
Evodiamine inhibits proliferation and induces apoptosis in gastric cancer cells.
Stomach Neoplasms
Exogenous morphine inhibits human gastric cancer MGC- 803 cell growth by cell cycle arrest and apoptosis induction.
Stomach Neoplasms
Expression of caspase-3 predicts prognosis in advanced noncardia gastric cancer.
Stomach Neoplasms
Expression of Fas ligand and caspase-3 contributes to formation of immune escape in gastric cancer.
Stomach Neoplasms
Five-lipoxygenase-activating protein inhibitor MK-886 induces apoptosis in gastric cancer through upregulation of p27kip1 and bax.
Stomach Neoplasms
G protein-coupled estrogen receptor-1 agonist induces chemotherapeutic effect via ER stress signaling in gastric cancer.
Stomach Neoplasms
Growth arrest-specific gene?1 is downregulated and inhibits tumor growth in gastric cancer.
Stomach Neoplasms
Growth inhibition and apoptosis of gastric cancer cell lines by Anemarrhena asphodeloides Bunge.
Stomach Neoplasms
Growth, invasion, metastasis, differentiation, angiogenesis and apoptosis of gastric cancer regulated by expression of PTEN encoding products.
Stomach Neoplasms
Helicobacter pylori infection upregulates interleukin-18 production from gastric epithelial cells.
Stomach Neoplasms
Immature colon carcinoma transcript-1 promotes proliferation of gastric cancer cells.
Stomach Neoplasms
Immunoexpression of DIABLO, AIF and cytochrome C in gastric adenocarcinoma assessed by tissue Microarray.
Stomach Neoplasms
Implication of Leptin-Signaling Proteins and Epstein-Barr Virus in Gastric Carcinomas.
Stomach Neoplasms
Induction of apoptosis by S-allylmercapto-L-cysteine, a biotransformed garlic derivative, on a human gastric cancer cell line.
Stomach Neoplasms
Influence of COX-2 inhibition by rofecoxib on serum and tumor progastrin and gastrin levels and expression of PPARgamma and apoptosis-related proteins in gastric cancer patients.
Stomach Neoplasms
Inhibition of CREPT restrains gastric cancer growth by regulation of cycle arrest, migration and apoptosis via ROS-regulated p53 pathway.
Stomach Neoplasms
Inhibitory Effect of Artesunate on Growth and Apoptosis of Gastric Cancer Cells.
Stomach Neoplasms
Inhibitory effects of eupatilin on tumor invasion of human gastric cancer MKN-1 cells.
Stomach Neoplasms
In vivo and in vitro inhibition of human gastric cancer progress by upregulating Kank1 gene.
Stomach Neoplasms
IRF-1 transcriptionally upregulates PUMA, which mediates the mitochondrial apoptotic pathway in IRF-1-induced apoptosis in cancer cells.
Stomach Neoplasms
Isobavachalcone induces the apoptosis of gastric cancer cells via inhibition of the Akt and Erk pathways.
Stomach Neoplasms
LCN2 Mediated by IL-17 Affects the Proliferation, Migration, Invasion and Cell Cycle of Gastric Cancer Cells by Targeting SLPI.
Stomach Neoplasms
Light activation of cyclometalated ruthenium complexes drives towards caspase 3 dependent apoptosis in gastric cancer cells.
Stomach Neoplasms
Loss of RUNX3 expression correlates with differentiation, nodal metastasis, and poor prognosis of gastric cancer.
Stomach Neoplasms
Luteolin exerts a marked antitumor effect in cMet-overexpressing patient-derived tumor xenograft models of gastric cancer.
Stomach Neoplasms
Maspin expression and its clinicopathological significance in tumorigenesis and progression of gastric cancer.
Stomach Neoplasms
MicroRNA-421 regulated by HIF-1? promotes metastasis, inhibits apoptosis, and induces cisplatin resistance by targeting E-cadherin and caspase-3 in gastric cancer.
Stomach Neoplasms
MicroRNA-524-5p suppresses cell proliferation and promotes cell apoptosis in gastric cancer by regulating CASP3.
Stomach Neoplasms
miR-106a Is frequently upregulated in gastric cancer and inhibits the extrinsic apoptotic pathway by targeting FAS.
Stomach Neoplasms
MiR-421 regulates apoptosis of BGC-823 gastric cancer cells by targeting caspase-3.
Stomach Neoplasms
miR-877-5p antagonizes the promoting effect of SP on the gastric cancer progression.
Stomach Neoplasms
Modulation of anti-apoptosis by endogenous IAP expression in MKN45 human gastric cancer cells.
Stomach Neoplasms
Modulatory effect of Tagetes erecta flowers essential oils via Nrf2/HO-1/NF-?B/p65 axis mediated suppression of N-methyl-N'nitro-N-nitroguanidine (MNNG) induced gastric cancer in rats.
Stomach Neoplasms
Molecular Epidemiologic Correlation Analysis Between Caspase3 Gene Polymorphism and Gastric Cancer Susceptibility.
Stomach Neoplasms
Nanomotor-Enabled pH-Responsive Intracellular Delivery of Caspase-3: Toward Rapid Cell Apoptosis.
Stomach Neoplasms
Non-steroidal anti-inflammatory drugs induce apoptosis in gastric cancer cells through up-regulation of bax and bak.
Stomach Neoplasms
Oridonin induces apoptosis in gastric cancer through Apaf-1, cytochrome c and caspase-3 signaling pathway.
Stomach Neoplasms
Oridonin, a novel lysine acetyltransferases inhibitor, inhibits proliferation and induces apoptosis in gastric cancer cells through p53- and caspase-3-mediated mechanisms.
Stomach Neoplasms
Osteopontin promotes the progression of gastric cancer through the NF-?B pathway regulated by the MAPK and PI3K.
Stomach Neoplasms
Overexpression of gastrokine 1 in gastric cancer cells induces fas-mediated apoptosis.
Stomach Neoplasms
Overexpression of gastrokine 1 in gastric cancer cells induces Fas-mediated apoptosis.
Stomach Neoplasms
Perilaldehyde activates AMP-activated protein kinase to suppress the growth of gastric cancer via induction of autophagy.
Stomach Neoplasms
Porphyran induces apoptosis related signal pathway in AGS gastric cancer cell lines.
Stomach Neoplasms
Potent inhibition of human gastric cancer by HER2-directed induction of apoptosis with anti-HER2 antibody and caspase-3 fusion protein.
Stomach Neoplasms
Procyanidin B2 induces apoptosis and autophagy in gastric cancer cells by inhibiting Akt/mTOR signaling pathway.
Stomach Neoplasms
Prognostic value of Caspase-3 expression in cancers of digestive tract: a meta-analysis and systematic review.
Stomach Neoplasms
Propofol inhibits proliferation and accelerates apoptosis of human gastric cancer cells by regulation of microRNA-451 and MMP-2 expression.
Stomach Neoplasms
Protein-bound polysaccharide K partially prevents apoptosis of circulating T cells induced by anti-cancer drug S-1 in patients with gastric cancer.
Stomach Neoplasms
REV-ERB? reduction is associated with clinicopathological features and prognosis in human gastric cancer.
Stomach Neoplasms
RP11-874J12.4, a novel lncRNA, confers chemoresistance in human gastric cancer cells by sponging miR-3972 and upregulating SSR2 expression.
Stomach Neoplasms
Sca-1 enriches for a cancer stem cell-like subpopulation in mouse gastric cancer.
Stomach Neoplasms
Shikonin Induces Apoptotic Cell Death via Regulation of p53 and Nrf2 in AGS Human Stomach Carcinoma Cells.
Stomach Neoplasms
Silencing ?-linked N-acetylglucosamine transferase induces apoptosis in human gastric cancer cells through PUMA and caspase-3 pathways.
Stomach Neoplasms
siRNA targeting midkine inhibits gastric cancer cells growth and induces apoptosis involved caspase-3,8,9 activation and mitochondrial depolarization.
Stomach Neoplasms
Sodium butyrate-induced DAPK-mediated apoptosis in human gastric cancer cells.
Stomach Neoplasms
Stable transfection of extrinsic Smac gene enhances apoptosis-inducing effects of chemotherapeutic drugs on gastric cancer cells.
Stomach Neoplasms
Synergistic antiproliferative effect of mTOR inhibitors in combination with 5-fluorouracil in scirrhous gastric cancer.
Stomach Neoplasms
Tanshinone IIA inhibits gastric carcinoma AGS cells by decreasing the protein expression of VEGFR and blocking Ras/Raf/MEK/ERK pathway.
Stomach Neoplasms
The effect of aloe-emodin-induced photodynamic activity on the apoptosis of human gastric cancer cells: A pilot study.
Stomach Neoplasms
The Effect of hsa-miR-451b Knockdown on Biological Functions of Gastric Cancer Stem-Like Cells.
Stomach Neoplasms
The effect of nitric oxide, growth factors, and estrogen on gastric cell migration.
Stomach Neoplasms
The extrinsic apoptotic signaling pathway in gastric adenocarcinomas assessed by tissue microarray.
Stomach Neoplasms
The mechanism study of lentiviral vector carrying methioninase enhances the sensitivity of drug-resistant gastric cancer cells to Cisplatin.
Stomach Neoplasms
Thimerosal-Induced Apoptosis in Human SCM1 Gastric Cancer Cells: Activation of p38 MAP Kinase and Caspase-3 Pathways without Involvement of [Ca2+]i Elevation.
Stomach Neoplasms
Thioridazine, an antipsychotic drug, elicits potent antitumor effects in gastric cancer.
Stomach Neoplasms
Thymoquinone inhibits growth and augments 5-fluorouracil-induced apoptosis in gastric cancer cells both in vitro and in vivo.
Stomach Neoplasms
Tumor-suppressive effects of 1,25-dihydroxyvitamin D3 in gastric cancer cells.
Stomach Neoplasms
Ultrafine particles of Ulmus davidiana var. japonica induce apoptosis of gastric cancer cells via activation of caspase and endoplasmic reticulum stress.
Stomach Neoplasms
Upregulation of heme oxygenase-1 and p21 confers resistance to apoptosis in human gastric cancer cells.
Stomach Neoplasms
Upregulation of microRNA-370 promotes cell apoptosis and inhibits proliferation by targeting PTEN in human gastric cancer.
Stomach Neoplasms
Ursolic acid promotes apoptosis of SGC-7901 gastric cancer cells through ROCK/PTEN mediated mitochondrial translocation of cofilin-1.
Stomach Neoplasms
Water-soluble Ru(II)-anethole compounds with promising cytotoxicity toward the human gastric cancer cell line AGS.
Stomach Neoplasms
[Adenovirus mediated IL-24 gene expression suppresses gastric cancer cell growth in vitro]
Stomach Neoplasms
[Chinese herbal medicine Euphorbia esula extract induces apoptosis and inhibits the proliferation, migration and invasion of multidrug resistant gastric carcinoma cells].
Stomach Neoplasms
[Diallyl trisulfide induces apoptosis of human gastric cancer cell line MGC803 through caspase-3 pathway]
Stomach Neoplasms
[Down-regulation of Caspase-3 expression in precancerous lesions and its relation to gastric carcinogenesis]
Stomach Neoplasms
[Effect of Paridis Rhizoma total saponins on apoptosis of human gastric cancer cell MKN-45 and Fas/FasL signaling pathway].
Stomach Neoplasms
[Effects of betulinic acid on apoptosis of human gastric cancer MGC-803 cells].
Stomach Neoplasms
[Expressions of gastrin and apoptosis-associated proteins involved in mitochondrial pathway in gastric cancer tissues and the clinical significance].
Stomach Neoplasms
[Mechanism of apoptosis induced by specific COX-2 inhibitor SC236 in gastric cancer cells]
Stomach Neoplasms
[Recombinant methioninase regulates PI3K/Akt/Glut-1 pathway and inhibits aerobic glycolysis to promote apoptosis of gastric cancer cells].
Stomach Neoplasms
[Regulatory effects on apoptotic activities of gastric cancer cell line by over-expression of Smac gene]
Stomach Neoplasms
[Study on apoptosis of human stomach SGC-7901 cells induced by extracts of Solanum lyratum]
Stomach Neoplasms
[Toosendanin induces apoptosis of human gastric cancer MGC-803 cells and its mechanism].
Stomach Ulcer
A Novel Role of Irbesartan in Gastroprotection against Indomethacin-Induced Gastric Injury in Rats: Targeting DDAH/ADMA and EGFR/ERK Signaling.
Stomach Ulcer
Ameliorative effects of telmisartan in diabetic rats with indomethacin-induced gastric ulceration.
Stomach Ulcer
Apoptosis in different gastric lesions and gastric cancer: relationship with Helicobacter pylori, overexpression of p53 and aneuploidy.
Stomach Ulcer
Beneficial effects of capsiate on ethanol-induced mucosal injury in rats are related to stimulation of calcitonin gene-related Peptide release.
Stomach Ulcer
Chrysin Modulates Genes Related to Inflammation, Tissue Remodeling, and Cell Proliferation in the Gastric Ulcer Healing.
Stomach Ulcer
Combined effect of bone marrow derived mesenchymal stem cells and nitric oxide inducer on injured gastric mucosa in a rat model.
Stomach Ulcer
Effect of the IGF-1/PTEN/Akt/FoxO signaling pathway on the development and healing of water immersion and restraint stress-induced gastric ulcers in rats.
Stomach Ulcer
Expression of apoptosis-associated microRNAs in ethanol-induced acute gastric mucosal injury via JNK pathway.
Stomach Ulcer
Gastroprotective effect of gallic acid against ethanol-induced gastric ulcer in rats: Involvement of the Nrf2/HO-1 signaling and anti-apoptosis role.
Stomach Ulcer
Role of basic fibroblast growth factor in the suppression of apoptotic caspase-3 during chronic gastric ulcer healing.
Stomach Ulcer
Vanillyl nonanoate protects rat gastric mucosa from ethanol-induced injury through a mechanism involving calcitonin gene-related peptide.
Stomatitis
Inhibition of caspases protects mice from radiation-induced oral mucositis and abolishes the cleavage of RNA-binding protein HuR.
Striatonigral Degeneration
Failure of caspase inhibition in the double-lesion rat model of striatonigral degeneration (multiple system atrophy).
Stroke
3,4-Dihydropyrimido(1,2-a)indol-10(2H)-ones as potent non-peptidic inhibitors of caspase-3.
Stroke
?-receptor antagonist treatment prevents activation of cell death signaling in the diabetic heart independent of its metabolic actions.
Stroke
A novel stroke therapy of pharmacologically induced hypothermia after focal cerebral ischemia in mice.
Stroke
A panel of biomarkers including caspase-3 and d-dimer may differentiate acute stroke from stroke-mimicking conditions in the emergency department.
Stroke
An in silico appraisal to identify high affinity anti-apoptotic synthetic tetrapeptide inhibitors targeting the mammalian caspase 3 enzyme.
Stroke
Astrocytic gap junctions composed of connexin 43 reduce apoptotic neuronal damage in cerebral ischemia.
Stroke
Bcl-2 overexpression protects against neuron loss within the ischemic margin following experimental stroke and inhibits cytochrome c translocation and caspase-3 activity.
Stroke
Caspase-8 and caspase-3 are expressed by different populations of cortical neurons undergoing delayed cell death after focal stroke in the rat.
Stroke
Catalpol Enhances Neurogenesis And Inhibits Apoptosis Of New Neurons Via BDNF, But Not The BDNF/Trkb Pathway.
Stroke
Cleaved caspase-3 expression after experimental stroke exhibits different phenotypes and is predominantly non-apoptotic.
Stroke
Detection of Active Caspase-3 in Mouse Models of Stroke and Alzheimer's Disease with a Novel Dual Positron Emission Tomography/Fluorescent Tracer [68Ga]Ga-TC3-OGDOTA.
Stroke
Differential variations of autophagy and apoptosis in permanent focal cerebral ischaemia rat model.
Stroke
Differentiating ischemic from hemorrhagic stroke using plasma biomarkers: The S100B/RAGE pathway.
Stroke
Down-regulation of MIF by NF?B under hypoxia accelerated neuronal loss during stroke.
Stroke
Dual role of caspase-11 in mediating activation of caspase-1 and caspase-3 under pathological conditions.
Stroke
Early inhibition of HIF-1alpha with small interfering RNA reduces ischemic-reperfused brain injury in rats.
Stroke
Functional motor recovery from brain ischemic insult by carbon nanotube-mediated siRNA silencing.
Stroke
Gastrodin improves the neurological score in MCAO rats by inhibiting inflammation and apoptosis, promoting revascularization.
Stroke
Increased apoptosis and inflammation after focal brain ischemia in mice lacking connexin43 in astrocytes.
Stroke
Increased expression and colocalization of GAP43 and CASP3 after brain ischemic lesion in mouse.
Stroke
Inhibiting caspase-3 activity blocks beta-catenin degradation after focal ischemia in rat.
Stroke
Inhibition of nNOS reduces ischemic cell death through down-regulating calpain and caspase-3 after experimental stroke.
Stroke
Inhibition of prolyl hydroxylases by dimethyloxaloylglycine after stroke reduces ischemic brain injury and requires hypoxia inducible factor-1?.
Stroke
Melanocortin MC? receptor agonists counteract late inflammatory and apoptotic responses and improve neuronal functionality after cerebral ischemia.
Stroke
Metformin Treatment in Post-stroke Period Prevents Nitrative Stress and Restores Angiogenic Signaling in the Brain in Diabetes.
Stroke
Mild hypothermia reduces activated caspase-3 up to 1 week after a focal cerebral ischemia induced by endothelin-1 in rats.
Stroke
Mild Therapeutic Hypothermia Protects the Brain from Ischemia/Reperfusion Injury through Upregulation of iASPP.
Stroke
miR-668 inhibitor attenuates mitochondrial membrane potential and protects against neuronal apoptosis in cerebral ischemic stroke.
Stroke
Molecular and cellular mechanisms of neuroprotection by vascular endothelial growth factor.
Stroke
Neuronal caspase-3 and PARP-1 correlate differentially with apoptosis and necrosis in ischemic human stroke.
Stroke
Neuroprotective actions of aminoguanidine involve reduced the activation of calpain and caspase-3 in a rat model of stroke.
Stroke
Neuroprotective Effects of Chronic Fenofibrate Treatment via Modulating the Immunoreactivity of Cleaved Caspase-3 in Stroke Induced by Transient Middle Cerebral Occlusion Rat Model.
Stroke
Neuroprotective effects of different frequency preconditioning exercise on neuronal apoptosis after focal brain ischemia in rats.
Stroke
Nitric oxide and cell signaling: in vivo evaluation of NO-dependent apoptosis by MRI and not NMR techniques.
Stroke
Panax notoginsenoside saponins Rb1 regulates the expressions of Akt/ mTOR/PTEN signals in the hippocampus after focal cerebral ischemia in rats.
Stroke
Puerarin protected the brain from cerebral ischemia injury via astrocyte apoptosis inhibition.
Stroke
Purinergic 2X7 receptor/NLRP3 pathway triggers neuronal apoptosis after ischemic stroke in the mouse.
Stroke
Reduction in programmed cell death and improvement in functional outcome of transient focal cerebral ischemia after administration of granulocyte-macrophage colony-stimulating factor in rats.
Stroke
Reperfusion differentially induces caspase-3 activation in ischemic core and penumbra after stroke in immature brain.
Stroke
Stroke promotes survival of nearby transplanted neural stem cells by decreasing their activation of caspase 3 while not affecting their differentiation.
Stroke
The Antiapoptotic Actions of Mood Stabilizers: Molecular Mechanisms and Therapeutic Potentials.
Stroke
The effect of concentration and duration of normobaric oxygen in reducing caspase-3 and -9 expression in a rat-model of focal cerebral ischaemia.
Stroke
The mechanism of taurine protection against endoplasmic reticulum stress in an animal stroke model of cerebral artery occlusion and stroke-related conditions in primary neuronal cell culture.
Stroke
Unilateral Blood Flow Decrease Induces Bilateral and Symmetric Responses in the Immature Brain.
Stroke
[Expressions of PDCD5 and other apoptosis-related proteins in muscle of patients with mitochondrial cytopathy]
Subarachnoid Hemorrhage
Apoptosis and necrosis in the circumventricular organs after experimental subarachnoid hemorrhage as detected with annexin V and caspase 3 immunostaining.
Subarachnoid Hemorrhage
Caspase-3 in serum predicts outcome after aneurysmal subarachnoid hemorrhage.
Subarachnoid Hemorrhage
Detection of caspase-3, neuron specific enolase, and high-sensitivity C-reactive protein levels in both cerebrospinal fluid and serum of patients after aneurysmal subarachnoid hemorrhage.
Subarachnoid Hemorrhage
Detection of Caspase-3, Neuron Specific Enolase, and High-sensitivity C-reactive Protein Levels in Both Cerebrospinal Fluid and Serum of Patients after Aneurysmal Subarachnoid Hemorrhage.
Subarachnoid Hemorrhage
Detection of caspase-3, neuron specific enolase, and high-sensitivity C-reactive protein levels in both cerebrospinal fluid and serum of patients after aneurysmal subarachnoid hemorrhage.
Subarachnoid Hemorrhage
Effect of General Anesthetics on Caspase-3 Levels in Patients With Aneurysmal Subarachnoid Hemorrhage: A Preliminary Study.
Subarachnoid Hemorrhage
Expression of caspase-3, Bax and Bcl-2 in hippocampus of rats with diabetes and subarachnoid hemorrhage.
Subarachnoid Hemorrhage
Glibenclamide reduces inflammation, vasogenic edema, and caspase-3 activation after subarachnoid hemorrhage.
Subarachnoid Hemorrhage
MMP-9 expression and activity is concurrent with endothelial cell apoptosis in the basilar artery after subarachnoid hemorrhaging in rats.
Subarachnoid Hemorrhage
Puerarin attenuates neurological deficits via Bcl-2/Bax/cleaved caspase-3 and Sirt3/SOD2 apoptotic pathways in subarachnoid hemorrhage mice.
Subarachnoid Hemorrhage
Simvastatin activates Akt/glycogen synthase kinase-3beta signal and inhibits caspase-3 activation after experimental subarachnoid hemorrhage.
Subarachnoid Hemorrhage
Tetramethylpyrazine Protects against Early Brain Injury after Experimental Subarachnoid Hemorrhage by Affecting Mitochondrial-Dependent Caspase-3 Apoptotic Pathway.
Subarachnoid Hemorrhage
Uncoupling of endothelial nitric oxide synthase after experimental subarachnoid hemorrhage.
Subarachnoid Hemorrhage
[Neuroprotection Mechanism of Lidocaine in Rabbits with Early Brain Injury Resulted from Subarachnoid Hemorrhage].
Sunburn
Apple Extract (Malus sp.) and Rutin as Photochemopreventive Agents: Evaluation of Ultraviolet B-Induced Alterations on Skin Biopsies and Tissue-Engineered Skin.
Sunburn
Catalase overexpression reduces UVB-induced apoptosis in a human xeroderma pigmentosum reconstructed epidermis.
Sunburn
Melanin acts as a potent UVB photosensitizer to cause an atypical mode of cell death in murine skin.
Sunburn
Photoprotective effects of Romanian propolis on skin of mice exposed to UVB irradiation.
Sunburn
Premature keratinocyte death and expression of marker proteins of apoptosis in human skin after UVB exposure.
Sunburn
Protection from photodamage by topical application of caffeine after ultraviolet irradiation.
Sunburn
Protection of normal human reconstructed epidermis from UV by catalase overexpression.
Sunburn
Stimulatory effect of topical application of caffeine on UVB-induced apoptosis in mouse skin.
Sunburn
Stimulatory effect of topical application of caffeine on UVB-induced apoptosis in the epidermis of p53 and Bax knockout mice.
Sunburn
Sulforaphane and phenylethyl isothiocyanate protect human skin against UVR-induced oxidative stress and apoptosis: role of Nrf2-dependent gene expression and antioxidant enzymes.
Sunburn
Voluntary exercise together with oral caffeine markedly stimulates UVB light-induced apoptosis and decreases tissue fat in SKH-1 mice.
Supranuclear Palsy, Progressive
Problems of cell death in neurodegeneration and Alzheimer's Disease.
Synovitis
Correlation of synovial caspase-3 concentration and the photodynamic effectiveness in the osteoarthritis treatment.
Synovitis
Novel protagonists in autoinflammatory arthritis of familial mediterranean Fever.
Synovitis
Strong expression of Bcl-2 in pigmented villonodular synovitis of the knee with aggressive clinical behaviour.
Synovitis, Pigmented Villonodular
Strong expression of Bcl-2 in pigmented villonodular synovitis of the knee with aggressive clinical behaviour.
Tauopathies
Expression of transcription factors c-Fos, c-Jun, CREB-1 and ATF-2, and caspase-3 in relation with abnormal tau deposits in Pick's disease.
Tauopathies
Influence of Early Life Lead (Pb) Exposure on ?-Synuclein, GSK-3? and Caspase-3 Mediated Tauopathy: Implications on Alzheimer's Disease.
Tauopathies
Role of caspase-3 in tau truncation at D421 is restricted in transgenic mouse models for tauopathies.
Tauopathies
Specific calpain inhibition by calpastatin prevents tauopathy and neurodegeneration and restores normal lifespan in tau P301L mice.
Telangiectasis
Simvastatin and purine analogs have a synergic effect on apoptosis of chronic lymphocytic leukemia cells.
Tendinopathy
Selected Clinical Features Fail to Predict Inflammatory Gene Expressions for TNF-?, TNFR1, NSMAF, Casp3 and IL-8 in Tendons of Patients with Rotator Cuff Tendinopathy.
Teratocarcinoma
Induction of apoptosis by hinokitiol, a potent iron chelator, in teratocarcinoma F9 cells is mediated through the activation of caspase-3.
Teratozoospermia
Quantitative study of caspase-3 activity in semen and after swim-up preparation in relation to sperm quality.
Teratozoospermia
Single and twin ongoing pregnancies in two cases of previous ART failure after ICSI performed with sperm sorted using annexin V microbeads.
Testicular Neoplasms
Gui-A-Gra Attenuates Testicular Dysfunction in Varicocele-Induced Rats via Oxidative Stress, ER Stress and Mitochondrial Apoptosis Pathway.
Testicular Neoplasms
Protective effect of hemin against cadmium-induced testicular damage in rats.
thioredoxin-dependent peroxiredoxin deficiency
Peroxiredoxin I deficiency increases keratinocyte apoptosis in a skin tumor model via the ROS-p38 MAPK pathway.
Thrombocytopenia
Apoptosis in platelets from adult patients with chronic idiopathic thrombocytopenic purpura.
Thrombocytopenia
Hemorrhage Exacerbates Radiation Effects on Survival, Leukocytopenia, Thrombopenia, Erythropenia, Bone Marrow Cell Depletion and Hematopoiesis, and Inflammation-Associated microRNAs Expression in Kidney.
Thrombocytopenia
Intravenous immunoglobulin inhibits anti-glycoprotein IIb-induced platelet apoptosis in a murine model of immune thrombocytopenia.
Thrombocytopenia
Role of vascular cell adhesion molecules and leukocyte apoptosis in the lymphopenia and thrombocytopenia of patients with severe acute respiratory syndrome (SARS).
Thrombosis
Expression of caspase-3 and hypoxia inducible factor 1? in hepatocellular carcinoma complicated by hemorrhage and necrosis.
Thymoma
a-Tocopherol modifies the expression of genes related to oxidative stress and apoptosis during invitro maturation and enhances the developmental competence of rabbit oocytes.
Thymoma
Cell quality control mechanisms maintain stemness and differentiation potential of P19 embryonic carcinoma cells.
Thymoma
Gliotoxin is a virulence factor of Aspergillus fumigatus: gliP deletion attenuates virulence in mice immunosuppressed with hydrocortisone.
Thymoma
In vivo and in vitro maturation of rabbit oocytes differently affects the gene expression profile, mitochondrial distribution, apoptosis and early embryo development.
Thymoma
microRNA-22 attenuates neuronal cell apoptosis in a cell model of traumatic brain injury.
Thymoma
miR-340 Inhibits Proliferation and Induces Apoptosis in Gastric Cancer Cell Line SGC-7901, Possibly via the AKT Pathway.
Thyroid Cancer, Papillary
Cytophotometric expression of Caspase-3 in papillary thyroid carcinoma in nodular goiter colloid.
Thyroid Cancer, Papillary
Evaluation of MMP2 and Caspase-3 expression in 107 cases of papillary thyroid carcinoma and its association with prognostic factors.
Thyroid Cancer, Papillary
The apoptotic effect of shikonin on human papillary thyroid carcinoma cells through mitochondrial pathway.
Thyroid Cancer, Papillary
The Effect of CASP3 rs4647610 and rs4647602 Polymorphisms on Tumour Size and Cancer Stage in Papillary Thyroid Carcinoma.
Thyroid Carcinoma, Anaplastic
A novel dendritic nanocarrier of polyamidoamine-polyethylene glycol-cyclic RGD for "smart" small interfering RNA delivery and in vitro antitumor effects by human ether-à-go-go-related gene silencing in anaplastic thyroid carcinoma cells.
Thyroid Carcinoma, Anaplastic
Cytochrome c release is upstream to activation of caspase-9, caspase-8, and caspase-3 in the enhanced apoptosis of anaplastic thyroid cancer cells induced by manumycin and paclitaxel.
Thyroid Neoplasms
Amifostine does not protect thyroid cancer cells in DNA damaging in vitro models.
Thyroid Neoplasms
Anti-proliferative and anti-invasive effects of ferulic acid in TT medullary thyroid cancer cells interacting with URG4/URGCP.
Thyroid Neoplasms
CXCR4/RhoA signaling pathway is involved in miR-128-regulated proliferation and apoptosis of human thyroid cancer cells.
Thyroid Neoplasms
Effects of CDK6 regulated by miR-298 on proliferation and apoptosis of thyroid cancer cells.
Thyroid Neoplasms
Effects of PPARgamma agonists on cell survival and focal adhesions in a Chinese thyroid carcinoma cell line.
Thyroid Neoplasms
Galectin-3 Inhibitors Suppress Anoikis Resistance and Invasive Capacity in Thyroid Cancer Cells.
Thyroid Neoplasms
Significance of survivin, caspase-3, and VEGF expression in thyroid carcinoma.
Thyroid Neoplasms
Synthesis and biological evaluation of 3-hydroxymethyl-5-(1H-1,2,3-triazol) isoxazolidines.
Thyroid Neoplasms
The C-terminal CD47/IAP-binding domain of thrombospondin-1 prevents camptothecin- and doxorubicin-induced apoptosis in human thyroid carcinoma cells.
Thyroiditis, Autoimmune
Impaired caspase-3 expression by peripheral T cells in chronic autoimmune thyroiditis and in autoimmune polyendocrine syndrome-2.
Tics
Resistance to DNA-damaging treatment in non-small cell lung cancer tumor-initiating cells involves reduced DNA-PK/ATM activation and diminished cell cycle arrest.
Tongue Neoplasms
Emodin induces apoptosis of human tongue squamous cancer SCC-4 cells through reactive oxygen species and mitochondria-dependent pathways.
Tongue Neoplasms
The inhibitory effect of a novel organoselenium compound BBSKE on the tongue cancer Tca8113 in vitro and in vivo.
Tonsillar Neoplasms
Expression of endothelial and inducible nitric oxide synthase and caspase-3 in tonsillar cancer, chronic tonsillitis and healthy tonsils.
Tonsillitis
Expression of endothelial and inducible nitric oxide synthase and caspase-3 in tonsillar cancer, chronic tonsillitis and healthy tonsils.
Tonsillitis
Quantification of cells expressing markers of proliferation and apoptosis in chronic tonsilitis.
Tooth Loss
Tooth loss causes spatial cognitive impairment in rats through decreased cerebral blood flow and increased glutamate.
Toxoplasmosis
Potential Molecular Mechanisms of Plantain in the Treatment of Gout and Hyperuricemia Based on Network Pharmacology.
Trichinellosis
The occupation of intestinal epithelium by Trichinella spiralis in BALB/C mice is not associated with local manifestation of apoptosis related factors.
Triple Negative Breast Neoplasms
An In Vivo Study for Targeted Delivery of Curcumin in Human Triple Negative Breast Carcinoma Cells Using Biocompatible PLGA Microspheres Conjugated with Folic Acid.
Triple Negative Breast Neoplasms
Cisplatin Loaded Multiwalled Carbon Nanotubes Induce Resistance in Triple Negative Breast Cancer Cells.
Triple Negative Breast Neoplasms
Combined treatment with vitamin C and methotrexate inhibits triple-negative breast cancer cell growth by increasing H2O2 accumulation and activating caspase-3 and p38 pathways.
Triple Negative Breast Neoplasms
Comparative proteomic profiling of triple-negative breast cancer reveals that up-regulation of RhoGDI-2 is associated to the inhibition of caspase 3 and caspase 9.
Triple Negative Breast Neoplasms
Disulfiram suppresses cancer stem-like properties and STAT3 signaling in triple-negative breast cancer cells.
Triple Negative Breast Neoplasms
Expression of cleaved caspase-3 predicts good chemotherapy response but poor survival for patients with advanced primary triple-negative breast cancer.
Triple Negative Breast Neoplasms
Glucose restriction decreases telomerase activity and enhances its inhibitor response on breast cancer cells: possible extra-telomerase role of BIBR 1532.
Triple Negative Breast Neoplasms
Highly potent monomethyl auristatin E prodrug activated by caspase-3 for the chemoradiotherapy of triple-negative breast cancer.
Triple Negative Breast Neoplasms
Puncta intended: connecting the dots between autophagy and cell stress networks.
Triple Negative Breast Neoplasms
Targeted inhibition of Notch1 gene enhances the killing effects of paclitaxel on triple negative breast cancer cells.
Truncus Arteriosus, Persistent
Type 2 diabetes mellitus induces congenital heart defects in murine embryos by increasing oxidative stress, endoplasmic reticulum stress and apoptosis.
Tuberculosis
BAG2 ameliorates endoplasmic reticulum stress-induced cell apoptosis in Mycobacterium tuberculosis-infected macrophages through selective autophagy.
Tuberculosis
High Frequencies of Caspase-3 Expressing Mycobacterium tuberculosis-Specific CD4+ T Cells Are Associated With Active Tuberculosis.
Tuberculosis
IL-32 is a host protective cytokine against Mycobacterium tuberculosis in differentiated THP-1 human macrophages.
Tuberculosis
Immunogenicity and protective efficacy of a tuberculosis DNA vaccine co-expressing pro-apoptotic caspase-3.
Tuberculosis
Mycobacterium tuberculosis infection causes different levels of apoptosis and necrosis in human macrophages and alveolar epithelial cells.
Tuberculosis
Mycobacterium tuberculosis promotes apoptosis in human neutrophils by activating caspase-3 and altering expression of Bax/Bcl-xL via an oxygen-dependent pathway.
Tuberculosis
PE-only/PE_PGRS proteins of Mycobacterium tuberculosis contain a conserved tetra-peptide sequence DEVS/DXXS that is a potential caspase-3 cleavage motif.
Tuberculosis
[Effects of Mycobacterium tuberculosis on apoptosis of mouse dendritic cells and activation of caspase-3, caspase-8].
Tuberculosis, Gastrointestinal
Role of mitochondrial oxidative stress on lymphocyte homeostasis in patients diagnosed with extra-pulmonary tuberculosis.
Tuberous Sclerosis
Differential Expression of MicroRNA-19b Promotes Proliferation of Cancer Stem Cells by Regulating the TSC1/mTOR Signaling Pathway in Multiple Myeloma.
Tuberous Sclerosis
MTORC1 coordinates the autophagy and apoptosis signaling in articular chondrocytes in osteoarthritic temporomandibular joint.
Uremia
Calpain is activated in experimental uremia: is calpain a mediator of uremia-induced myocardial injury?
Uremia
The effect of uremia and hemodialysis on caspase-1 and caspase-3 activity in neutrophils.
Ureteral Obstruction
Effect of unilateral ureteral obstruction and anti-angiotensin II treatment on renal tubule and interstitial cell apoptosis in rats.
Ureteral Obstruction
GSDME-mediated pyroptosis promotes inflammation and fibrosis in obstructive nephropathy.
Urinary Bladder Neoplasms
?-Elemene promotes cisplatin-induced cell death in human bladder cancer and other carcinomas.
Urinary Bladder Neoplasms
A novel Bifidobacterium infantis-mediated TK/GCV suicide gene therapy system exhibits antitumor activity in a rat model of bladder cancer.
Urinary Bladder Neoplasms
Antisense oligonucleotide targeting Livin induces apoptosis of human bladder cancer cell via a mechanism involving caspase 3.
Urinary Bladder Neoplasms
Association of death receptor 4, Caspase 3 and 5 gene polymorphism with increased risk to bladder cancer in North Indians.
Urinary Bladder Neoplasms
Baicalein induces apoptosis via a mitochondrial-dependent caspase activation pathway in T24 bladder cancer cells.
Urinary Bladder Neoplasms
Bergenin inhibits bladder cancer progression via activating the PPAR?/PTEN/Akt signal pathway.
Urinary Bladder Neoplasms
Brucea javanica oil induces apoptosis in T24 bladder cancer cells via upregulation of caspase-3, caspase-9, and inhibition of NF-kappaB and COX-2 expressions.
Urinary Bladder Neoplasms
Cancer-specific promoters for expression-targeted gene therapy: ran, brms1 and mcm5.
Urinary Bladder Neoplasms
Chitosan induces apoptosis via caspase-3 activation in bladder tumor cells.
Urinary Bladder Neoplasms
Chloroquine and hydroxychloroquine inhibit bladder cancer cell growth by targeting basal autophagy and enhancing apoptosis.
Urinary Bladder Neoplasms
Cinobufacini promotes apoptosis of bladder cancer cells by influencing the expression of autophagy-related genes.
Urinary Bladder Neoplasms
CpG Oligodeoxynucleotides Induces Apoptosis of Human Bladder Cancer Cells via Caspase-3-Bax/Bcl-2-p53 Axis.
Urinary Bladder Neoplasms
Diallyl disulfide (DADS) induced apoptosis undergo caspase-3 activity in human bladder cancer T24 cells.
Urinary Bladder Neoplasms
Diindolylmethane and Lupeol Modulates Apoptosis and Cell Proliferation in N-Butyl-N-(4-Hydroxybutyl) Nitrosamine Initiated and Dimethylarsinic Acid Promoted rat Bladder Carcinogenesis.
Urinary Bladder Neoplasms
Effect of Combined Treatment of Radiation and Tissue-specific Recombinant Oncolytic Adenovirus on bladder cancer cells.
Urinary Bladder Neoplasms
Experimental investigation of a combinational iron chelating protoporphyrin IX prodrug for fluorescence detection and photodynamic therapy.
Urinary Bladder Neoplasms
Fangchinoline Induces Apoptosis, Autophagy and Energetic Impairment in Bladder Cancer.
Urinary Bladder Neoplasms
Guggulsterone induces apoptosis and inhibits lysosomal-dependent migration in human bladder cancer cells.
Urinary Bladder Neoplasms
Heptaphylline suppresses the proliferation and migration of human bladder cancer cells via induction of intrinsic apoptosis, autophagy and inhibition of ?-catenin signalling pathway.
Urinary Bladder Neoplasms
Human agonistic antibody to tumor necrosis factor-related apoptosis-inducing ligand receptor 2 induces cytotoxicity and apoptosis in prostate cancer and bladder cancer cells.
Urinary Bladder Neoplasms
Immunohistochemical study of pro-apoptotic factors Bax, Fas and CPP32 in urinary bladder cancer: prognostic implications.
Urinary Bladder Neoplasms
In vitro antioxidant and antiproliferative effects of ellagic acid and its colonic metabolite, urolithins, on human bladder cancer T24 cells.
Urinary Bladder Neoplasms
Inhibition of growth, migration and invasion of human bladder cancer cells by antrocin, a sesquiterpene lactone isolated from Antrodia cinnamomea, and its molecular mechanisms.
Urinary Bladder Neoplasms
Inhibition of thromboxane synthase activity modulates bladder cancer cell responses to chemotherapeutic agents.
Urinary Bladder Neoplasms
Intravenous Administration Is an Effective and Safe Route for Cancer Gene Therapy Using the Bifidobacterium-Mediated Recombinant HSV-1 Thymidine Kinase and Ganciclovir.
Urinary Bladder Neoplasms
Knockdown of KNTC1 Inhibits the Proliferation, Migration and Tumorigenesis of Human Bladder Cancer Cells and Induces Apoptosis.
Urinary Bladder Neoplasms
Livin, Survivin and Caspase 3 as early recurrence markers in non-muscle-invasive bladder cancer.
Urinary Bladder Neoplasms
Lycorine induces apoptosis of bladder cancer T24 cells by inhibiting phospho-Akt and activating the intrinsic apoptotic cascade.
Urinary Bladder Neoplasms
Microvesicles derived from human umbilical cord Wharton's jelly mesenchymal stem cells attenuate bladder tumor cell growth in vitro and in vivo.
Urinary Bladder Neoplasms
Overexpression of immunoglobulin G prompts cell proliferation and inhibits cell apoptosis in human urothelial carcinoma.
Urinary Bladder Neoplasms
Overexpression of PML induced apoptosis in bladder cancer cell by caspase dependent pathway.
Urinary Bladder Neoplasms
Potential therapeutic effects of N-butylidenephthalide from Radix Angelica Sinensis (Danggui) in human bladder cancer cells.
Urinary Bladder Neoplasms
Prognostic significance of apoptotic cell death in bladder cancer: a tissue microarray study on 179 urothelial carcinomas from cystectomy specimens.
Urinary Bladder Neoplasms
Rb deficiency accelerates progression of carcinoma of the urinary bladder in vivo and in vitro through inhibiting autophagy and apoptosis.
Urinary Bladder Neoplasms
Rb knockdown accelerates bladder cancer progression through E2F3 activation.
Urinary Bladder Neoplasms
Shikonin-induced apoptosis involves caspase-3 activity in a human bladder cancer cell line (T24).
Urinary Bladder Neoplasms
Silibinin causes cell cycle arrest and apoptosis in human bladder transitional cell carcinoma cells by regulating CDKI-CDK-cyclin cascade, and caspase 3 and PARP cleavages.
Urinary Bladder Neoplasms
TAT-Apoptin induces apoptosis in the human bladder cancer EJ cell line and regulates Bax, Bcl-2, caspase-3 and survivin expression.
Urinary Bladder Neoplasms
The Apoptosis Mechanism of Epirubicin Combined with BCG on Human Bladder Cancer Cells.
Urinary Bladder Neoplasms
The intracellular domain of UNC5B facilities proliferation and metastasis of bladder cancer cells.
Urinary Bladder Neoplasms
The Role of Pyruvate Dehydrogenase Kinase-4 (PDK4) in Bladder Cancer and Chemoresistance.
Urinary Bladder Neoplasms
Two hour exposure to sodium butyrate sensitizes bladder cancer to anticancer drugs.
Urinary Bladder Neoplasms
URGCP/URG4 promotes apoptotic resistance in bladder cancer cells by activating NF-?B signaling.
Urinary Bladder Neoplasms
Use of combined apoptosis biomarkers for prediction of bladder cancer recurrence and mortality after radical cystectomy.
Urinary Bladder Neoplasms
Vitamin K2 Induces Mitochondria-Related Apoptosis in Human Bladder Cancer Cells via ROS and JNK/p38 MAPK Signal Pathways.
Urinary Bladder Neoplasms
[Knock-down of DAB2 interacting protein (DAB2IP) promotes proliferation and inhibits apoptosis of bladder cancer cells].
Urinary Bladder Neoplasms
[Mechanisms for effect of osthole on inhibiting the growth and invasion of bladder cancer cells].
Urinary Bladder Neoplasms
[Possibilities of in silico estimations for the development of pharmaceutical composition phytoladaptogene cytotoxic for bladder cancer cells].
Uterine Cervical Neoplasms
A novel surface-enhanced Raman scattering probe based on Au nanoboxes for dynamic monitoring of caspase-3 during cervical cancer cell apoptosis.
Uterine Cervical Neoplasms
A study on antioxidant and apoptotic effect of Azadirachta Indica (neem) in cases of cervical cancer.
Uterine Cervical Neoplasms
Alantolactone exhibits selective antitumor effects in HELA human cervical cancer cells by inhibiting cell migration and invasion, G2/M cell cycle arrest, mitochondrial mediated apoptosis and targeting Nf-kB signalling pathway.
Uterine Cervical Neoplasms
Anti-apoptotic effect of caspase inhibitors on H2O2-treated HeLa cells through early suppression of its oxidative stress.
Uterine Cervical Neoplasms
Anti-Condyloma acuminata mechanism of microRNAs-375 modulates HPV in cervical cancer cells via the UBE3A and IGF-1R pathway.
Uterine Cervical Neoplasms
Anticancerous potential of polysaccharides sequentially extracted from Polygonatum cyrtonema Hua in Human cervical cancer Hela cells.
Uterine Cervical Neoplasms
ARL6IP1 mediates cisplatin-induced apoptosis in CaSki cervical cancer cells.
Uterine Cervical Neoplasms
Aspirin Has Antitumor Effects via Expression of Calpain Gene in Cervical Cancer Cells.
Uterine Cervical Neoplasms
Association of Casp3 microRNA Target Site (1049216) SNP With the Risk and Progress of Cervical Squamous Cell Carcinoma.
Uterine Cervical Neoplasms
Atorvastatin suppresses the progression of cervical cancer via regulation of autophagy.
Uterine Cervical Neoplasms
Blockade of BAFF Receptor BR3 on T Cells Enhances Their Activation and Cytotoxicity.
Uterine Cervical Neoplasms
Chan-Yu-Bao-Yuan-Tang and 5-fluorouracil synergistically induce apoptosis by means of the caspase-3 signaling pathway in lung and cervical cancer cells.
Uterine Cervical Neoplasms
Comprehensive analysis of lncRNAs microarray profile and mRNA-lncRNA co-expression in oncogenic HPV-positive cervical cancer cell lines.
Uterine Cervical Neoplasms
Coumarin induces cell cycle arrest and apoptosis in human cervical cancer HeLa cells through a mitochondria- and caspase-3 dependent mechanism and NF-kappaB down-regulation.
Uterine Cervical Neoplasms
Deficiency of caspase 3 in tumor xenograft impairs therapeutic effect of measles virus Edmoston strain.
Uterine Cervical Neoplasms
Design and Development of Spray-Dried Microsystems to Improve Technological and Functional Properties of Bioactive Compounds from Hazelnut Shells.
Uterine Cervical Neoplasms
Down-regulation of miR-320 associated with cancer progression and cell apoptosis via targeting Mcl-1 in cervical cancer.
Uterine Cervical Neoplasms
Effects of Smac gene over-expression on the radiotherapeutic sensitivities of cervical cancer cell line HeLa.
Uterine Cervical Neoplasms
Elevated cleaved caspase-3 is associated with shortened overall survival in several cancer types.
Uterine Cervical Neoplasms
EM23, a natural sesquiterpene lactone, targets thioredoxin reductase to activate JNK and cell death pathways in human cervical cancer cells.
Uterine Cervical Neoplasms
Expression of survivin, caspase-3 and p53 in cervical cancer assessed by tissue microarray: correlation with clinicopathology and prognosis.
Uterine Cervical Neoplasms
Expression of survivin, cyclinD1, p21(WAF1), caspase-3 in cervical cancer and its relation with prognosis.
Uterine Cervical Neoplasms
Grape seed proanthocyanidins (GSPs) inhibit the growth of cervical cancer by inducing apoptosis mediated by the mitochondrial pathway.
Uterine Cervical Neoplasms
Hazelnut (Corylus avellana L.) Shells Extract: Phenolic Composition, Antioxidant Effect and Cytotoxic Activity on Human Cancer Cell Lines.
Uterine Cervical Neoplasms
Hedgehog pathway regulators influence cervical cancer cell proliferation, survival and migration.
Uterine Cervical Neoplasms
Immunohistochemical study of NF-?B p65, c-IAP2 and caspase-3 expression in cervical cancer.
Uterine Cervical Neoplasms
Indole-3-carbinol and diindolylmethane induce apoptosis of human cervical cancer cells and in murine HPV16-transgenic preneoplastic cervical epithelium.
Uterine Cervical Neoplasms
Induction of Apoptosis by Green Synthesized Gold Nanoparticles Through Activation of Caspase-3 and 9 in Human Cervical Cancer Cells.
Uterine Cervical Neoplasms
Induction of apoptosis by the inhibitors of poly(ADP-ribose)polymerase in HeLa cells.
Uterine Cervical Neoplasms
Inhibition of ADP-ribosylation factor-like 6 interacting protein 1 suppresses proliferation and reduces tumor cell invasion in CaSki human cervical cancer cells.
Uterine Cervical Neoplasms
Inhibition of metastasis-associated lung adenocarcinoma transcript 1 in CaSki human cervical cancer cells suppresses cell proliferation and invasion.
Uterine Cervical Neoplasms
Involvement of both extrinsic and intrinsic apoptotic pathways in apoptosis induced by genistein in human cervical cancer cells.
Uterine Cervical Neoplasms
Jab1 Inhibition by Methanolic Extract of Moringa Oleifera Leaves in Cervical Cancer Cells: A Potent Targeted Therapeutic Approach.
Uterine Cervical Neoplasms
Liquiritin (LT) exhibits suppressive effects against the growth of human cervical cancer cells through activating Caspase-3 in vitro and xenograft mice in vivo.
Uterine Cervical Neoplasms
Long Non-Coding RNA LINC00511 Accelerates Proliferation and Invasion in Cervical Cancer Through Targeting miR-324-5p/DRAM1 Axis.
Uterine Cervical Neoplasms
MALAT1 promotes cisplatin resistance in cervical cancer by activating the PI3K/AKT pathway.
Uterine Cervical Neoplasms
MFAP5 suppression inhibits migration/invasion, regulates cell cycle and induces apoptosis via promoting ROS production in cervical cancer.
Uterine Cervical Neoplasms
MicroRNA-744 inhibited cervical cancer growth and progression through apoptosis induction by regulating Bcl-2.
Uterine Cervical Neoplasms
miR-126-5p Restoration Promotes Cell Apoptosis in Cervical Cancer by Targeting Bcl2l2.
Uterine Cervical Neoplasms
miR-454-3p promotes proliferation and induces apoptosis in human cervical cancer cells by targeting TRIM3.
Uterine Cervical Neoplasms
MiRNA-211 triggers an autophagy-dependent apoptosis in cervical cancer cells: regulation of Bcl-2.
Uterine Cervical Neoplasms
Modulating Bcl-2 Family Proteins and Caspase-3 in Induction of Apoptosis by Paeoniflorin in Human Cervical Cancer Cells.
Uterine Cervical Neoplasms
MSX1 induces G0/G1 arrest and apoptosis by suppressing Notch signaling and is frequently methylated in cervical cancer.
Uterine Cervical Neoplasms
OGDHL is a modifier of AKT-dependent signaling and NF-?B function.
Uterine Cervical Neoplasms
Phenethyl Isothiocyanate Induces Apoptosis Through ROS Generation and Caspase-3 Activation in Cervical Cancer Cells.
Uterine Cervical Neoplasms
Potentiation of Apoptin-induced-apoptosis by Cecropin B-like Antibacterial Peptide ABPs1 in Human HeLa Cervical Cancer Cell Lines is associated with Membrane Pores formation and Caspase-3 Activation.
Uterine Cervical Neoplasms
PTEN downregulation induces apoptosis and cell cycle arrest in uterine cervical cancer cells.
Uterine Cervical Neoplasms
Realgar-induced apoptosis of cervical cancer cell line Siha via cytochrome C release and caspase-3 and caspase-9 activation.
Uterine Cervical Neoplasms
RHCG suppresses cervical cancer progression through inhibiting migration and inducing apoptosis regulated by TGF-?1.
Uterine Cervical Neoplasms
Role of activating transcription factor 3 on TAp73 stability and apoptosis in paclitaxel-treated cervical cancer cells.
Uterine Cervical Neoplasms
Stress-induced endocytosis and degradation of epidermal growth factor receptor are two independent processes.
Uterine Cervical Neoplasms
Study on the effect of Integrin ?V?6 on proliferation and apoptosis of cervical cancer cells.
Uterine Cervical Neoplasms
Synergistic anticancer activity of dietary tea polyphenols and bleomycin hydrochloride in human cervical cancer cell: Caspase-dependent and independent apoptotic pathways.
Uterine Cervical Neoplasms
Synergistic interaction between tetra-arsenic oxide and paclitaxel in human cancer cells in vitro.
Uterine Cervical Neoplasms
Tafazzin (TAZ) promotes the tumorigenicity of cervical cancer cells and inhibits apoptosis.
Uterine Cervical Neoplasms
Targeted delivery of a novel anticancer compound anisomelic acid using chitosan-coated porous silica nanorods for enhancing the apoptotic effect.
Uterine Cervical Neoplasms
Tetrandrine suppresses cervical cancer growth by inducing apoptosis in vitro and in vivo.
Uterine Cervical Neoplasms
The combined treatment of aspirin and radiation induces apoptosis by the regulation of bcl-2 and caspase-3 in human cervical cancer cell.
Uterine Cervical Neoplasms
Triacontanoic ester of 5''-hydroxyjustisolin: Tumour suppressive role in cervical cancer via Bcl-2, BAX and caspase-3 mediated signalling.
Uterine Cervical Neoplasms
Triggering of death receptor apoptotic signaling by human papillomavirus 16 E2 protein in cervical cancer cell lines is mediated by interaction with c-FLIP.
Uterine Cervical Neoplasms
Ultrasound-responsive microbubbles for sonography-guided siRNA delivery.
Uterine Cervical Neoplasms
USP18 promotes cell proliferation and suppressed apoptosis in cervical cancer cells via activating AKT signaling pathway.
Uterine Cervical Neoplasms
[Hederagenin inhibits proliferation and promotes apoptosis of cervical cancer CaSki cells by blocking STAT3 pathway].
Uterine Cervical Neoplasms
[Influence of survivin gene repression by RNA interference on the radiosensitivity and chemosensitivity to cisplatin of cervical cancer cell HeLa]
Uveitis
Protein kinase Czeta (PKCzeta) regulates ocular inflammation and apoptosis in endotoxin-induced uveitis (EIU): signaling molecules involved in EIU resolution by PKCzeta inhibitor and interleukin-13.
Vaccinia
Molluscum contagiosum virus inhibitors of apoptosis: The MC159 v-FLIP protein blocks Fas-induced activation of procaspases and degradation of the related MC160 protein.
Vaccinia
Protein kinase Calpha promotes apoptotic cell death in gastric cancer cells depending upon loss of anchorage.
Vaccinia
The vaccinia virus F1L protein interacts with the proapoptotic protein Bak and inhibits Bak activation.
Vaccinia
Vaccinia virus infection disarms the mitochondrion-mediated pathway of the apoptotic cascade by modulating the permeability transition pore.
Varicocele
Expression of Hypoxia-Inducible Factor1-? in Varicocele Disease: a Comprehensive Systematic Review.
Varicocele
Involved intrinsic apoptotic pathway of testicular tissues in varicocele-induced rats.
Varicocele
Seminal plasma miR-210-3p induces spermatogenic cell apoptosis by activating caspase-3 in patients with varicocele.
Varicocele
[Apoptosis and expression of caspase-3 protein in germ cells of varicocele rats]
Varicose Ulcer
Expression of apoptosis- and cell cycle-related proteins in epidermis of venous leg and diabetic foot ulcers.
Vascular Calcification
Curcumin attenuates osteogenic differentiation and calcification of rat vascular smooth muscle cells.
Vascular Calcification
Effect of endoplasmic reticulum stress-induced apoptosis in the role of periodontitis on vascular calcification in a rat model.
Vascular Diseases
Activated protein C inhibits bisphosphonate-induced endothelial cell death via the endothelial protein C receptor and nuclear factor-?B pathways.
Vascular Diseases
Endothelial cell apoptosis is induced by fetal plasma from pregnancy with umbilical placental vascular disease.
Vascular Diseases
The renin inhibitor aliskiren upregulates pro-angiogenic cells and reduces atherogenesis in mice.
Vascular System Injuries
A depleting antibody toward sca-1 mitigates a surge of CD34(+)/c-kit(+) progenitors and reduces vascular restenosis in a murine vascular injury model.
Vascular System Injuries
Acute coronary artery injury in dogs following administration of CI-1034, an endothelin A receptor antagonist.
Vascular System Injuries
HDAC6 inhibition prevents TNF-?-induced caspase 3 activation in lung endothelial cell and maintains cell-cell junctions.
Vascular System Injuries
Induction of oxidative and nitrosative damage leads to cerebrovascular inflammation in an animal model of mild traumatic brain injury induced by primary blast.
Vasculitis
Apoptosis and nitrative stress associated with phosphodiesterase inhibitor-induced mesenteric vasculitis in rats.
Vasculitis
Involvement of p53, p21, and Caspase-3 in Apoptosis of Coronary Artery Smooth Muscle Cells in a Kawasaki Vasculitis Mouse Model.
Ventricular Dysfunction, Left
Activation of caspase-3 may not contribute to postresuscitation myocardial dysfunction.
Ventricular Dysfunction, Left
Regulation of caspase 3 and Fas in pressure overload-induced left ventricular dysfunction.
Ventricular Fibrillation
Activation of caspase-3 may not contribute to postresuscitation myocardial dysfunction.
Vertigo
[Effects of fast-twisting long-retaining acupuncture therapy on apoptosis and expression of related proteins in vestibular nucleus in rats with vertigo induced by posterior circulation ischemia].
Vesicular Stomatitis
Requirement of caspase-3 for efficient apoptosis induction and caspase-7 activation but not viral replication or cell rounding in cells infected with vesicular stomatitis virus.
Viremia
Hepatic fibrosis and immune phenotype vary by HCV viremia in HCV/HIV co-infected subjects: A Women's interagency HIV study.
Viremia
Intrahepatic infiltrating NK and CD8 T cells cause liver cell death in different phases of dengue virus infection.
Virus Diseases
Antiviral activity of a synthesized shikonin ester against influenza A (H1N1) virus and insights into its mechanism.
Virus Diseases
Autophagy, apoptosis, vitamin D, and vitamin D receptor in hepatocellular carcinoma associated with hepatitis C virus.
Virus Diseases
Caspase 3 activation is essential for efficient influenza virus propagation.
Virus Diseases
Caspase 3 is not essential for the induction of anergy or multiple pathways of CD8+ T-cell death.
Virus Diseases
Caspase inhibition protects against reovirus-induced myocardial injury in vitro and in vivo.
Virus Diseases
Expression of tumour necrosis factor-related apoptosis-inducing ligand and caspase-3 in relation to grade of inflammation and stage of fibrosis in chronic hepatitis C.
Virus Diseases
Identification and characterization of a tumor necrosis factor receptor like protein encoded by Singapore grouper iridovirus.
Virus Diseases
Impact of caspase-1/11, -3, -7, or IL-1?/IL-18 deficiency on rabies virus-induced macrophage cell death and onset of disease.
Virus Diseases
Importin-? and exportin-5 are indicators of acute viral infection: Correlation of their detection with commercially available detection kits.
Virus Diseases
Influenza virus aggravates the ox-LDL-induced apoptosis of human endothelial cells via promoting p53 signaling.
Virus Diseases
Lactate dehydrogenase leakage as a marker for apoptotic cell degradation induced by influenza virus infection in human fetal membrane cells.
Virus Diseases
Persistent measles virus infection of mouse neural cells lacking known human entry receptors.
Virus Diseases
Reovirus-associated reduction of microRNA-let-7d is related to the increased apoptotic death of cancer cells in clinical samples.
Virus Diseases
Restriction of H1N1 influenza virus infection by selenium nanoparticles loaded with ribavirin via resisting caspase-3 apoptotic pathway.
Virus Diseases
Sendai virus infection induces apoptosis through activation of caspase-8 (FLICE) and caspase-3 (CPP32).
Virus Diseases
The Role of Caspase-12 in Retinal Bystander Cell Death and Innate Immune Responses against MCMV Retinitis.
Virus Diseases
Tioman virus infection in experimentally infected mouse brain and its association with apoptosis.
Virus Diseases
Trans-splicing group I intron targeting hepatitis C virus IRES mediates cell death upon viral infection in Huh7.5 cells.
Virus Diseases
Virus infection induces proteolytic processing of IL-18 in human macrophages via caspase-1 and caspase-3 activation.
Virus Diseases
[Antagonism of baicalin on cell cyclical distribution and cell apoptosis in A549 cells infected with influenza A (H1N1) virus].
Vulvar Neoplasms
Identification of potential prognostic markers for vulvar cancer using immunohistochemical staining of tissue microarrays.
Wasting Syndrome
Apoptosis in postweaning multisystemic wasting syndrome (PMWS) hepatitis in pigs naturally infected with porcine circovirus type 2 (PCV2).
West Nile Fever
Caspase 3-dependent cell death of neurons contributes to the pathogenesis of West Nile virus encephalitis.
West Nile Fever
Virus-induced Ca2+ influx extends survival of west nile virus-infected cells.
Whipple Disease
Increased levels of circulating IL-16 and apoptosis markers are related to the activity of Whipple's disease.
Whooping Cough
Butyrate and propionate induced activated or non-activated neutrophil apoptosis via HDAC inhibitor activity but without activating GPR-41/GPR-43 pathways.
Whooping Cough
Caspase-dependent apoptosis of cells expressing the chemokine receptor CXCR4 is induced by cell membrane-associated human immunodeficiency virus type 1 envelope glycoprotein (gp120).
Whooping Cough
Monocyte chemoattractant protein-1 and macrophage inflammatory protein-2 are involved in both excitotoxin-induced neurodegeneration and regeneration.
Whooping Cough
Non-phosphorylated FTY720 Induces Apoptosis of Human Microglia by Activating SREBP2.
Whooping Cough
Sphingosine 1-phosphate triggers apoptotic signal for B16 melanoma cells via ERK and caspase activation.
Whooping Cough
Sphingosine 1-phosphate triggers both apoptotic and survival signals for human hepatic myofibroblasts.
Wilms Tumor
BASP1 Suppresses Cell Growth and Metastasis through Inhibiting Wnt/?-Catenin Pathway in Gastric Cancer.
Wilms Tumor
Cellular injury associated with renal thrombotic microangiopathy in human immunodeficiency virus-infected macaques.
Wilms Tumor
In situ evaluation of podocytes in patients with focal segmental glomerulosclerosis and minimal change disease.
Wilms Tumor
Knockdown of Expression of Cdk5 or p35 (a Cdk5 Activator) Results in Podocyte Apoptosis.
Xeroderma Pigmentosum
Involvement of human heat shock protein 90 alpha in nicotine-induced apoptosis.
Yersinia Infections
Cell death triggered by Yersinia enterocolitica identifies processing of the proinflammatory signal adapter MyD88 as a general event in the execution of apoptosis.
Zika Virus Infection
Identification of small-molecule inhibitors of Zika virus infection and induced neural cell death via a drug repurposing screen.
Zika Virus Infection
Western Zika Virus in Human Fetal Neural Progenitors Persists Long Term with Partial Cytopathic and Limited Immunogenic Effects.
Please wait a moment until the data is sorted. This message will disappear when the data is sorted.
KM VALUE [mM]
SUBSTRATE
ORGANISM
UNIPROT
COMMENTARY
LITERATURE
IMAGE
0.0004
N-(5(6)-carboxyfluoresceinyl)-6-aminohexanoyl-Asp-Ala-Pro-Asp-6-aminohexanoyl-N6-[methyl red]-Lys-[N-(6-aminohexyl)-Gly]8-N2-(6-aminohexyl)-Gly-NH2
pH and temperature not specified in the publication
0.0015
N-(5(6)-carboxyfluoresceinyl)-6-aminohexanoyl-Asp-Ala-Val-Asp-6-aminohexanoyl-N6-[methyl red]-Lys-[N-(6-aminohexyl)-Gly]8-N2-(6-aminohexyl)-Gly-NH2
pH and temperature not specified in the publication
0.0008
N-(5(6)-carboxyfluoresceinyl)-6-aminohexanoyl-Asp-Asn-Pro-Asp-6-aminohexanoyl-N6-[methyl red]-Lys-[N-(6-aminohexyl)-Gly]8-N2-(6-aminohexyl)-Gly-NH2
pH and temperature not specified in the publication
0.0004
N-(5(6)-carboxyfluoresceinyl)-6-aminohexanoyl-Asp-Asn-Val-Asp-6-aminohexanoyl-N6-[methyl red]-Lys-[N-(6-aminohexyl)-Gly]8-N2-(6-aminohexyl)-Gly-NH2
pH and temperature not specified in the publication
0.0006
N-(5(6)-carboxyfluoresceinyl)-6-aminohexanoyl-Asp-Glu-Val-Asp-6-aminohexanoyl-N6-[methyl red]-Lys-[N-(6-aminohexyl)-Gly]8-N2-(6-aminohexyl)-Gly-NH2
pH and temperature not specified in the publication
0.0006
N-(5(6)-carboxyfluoresceinyl)-6-aminohexanoyl-Asp-Gly-Pro-Asp-6-aminohexanoyl-N6-[methyl red]-Lys-[N-(6-aminohexyl)-Gly]8-N2-(6-aminohexyl)-Gly-NH2
pH and temperature not specified in the publication
0.0003
N-(5(6)-carboxyfluoresceinyl)-6-aminohexanoyl-Asp-Gly-Val-Asp-6-aminohexanoyl-N6-[methyl red]-Lys-[N-(6-aminohexyl)-Gly]8-N2-(6-aminohexyl)-Gly-NH2
pH and temperature not specified in the publication
0.0002
N-(5(6)-carboxyfluoresceinyl)-6-aminohexanoyl-Asp-Leu-Pro-Asp-6-aminohexanoyl-N6-[methyl red]-Lys-[N-(6-aminohexyl)-Gly]8-N2-(6-aminohexyl)-Gly-NH2
pH and temperature not specified in the publication
0.0008
N-(5(6)-carboxyfluoresceinyl)-6-aminohexanoyl-Asp-Leu-Val-Asp-6-aminohexanoyl-N6-[methyl red]-Lys-[N-(6-aminohexyl)-Gly]8-N2-(6-aminohexyl)-Gly-NH2
pH and temperature not specified in the publication
0.0002
N-(5(6)-carboxyfluoresceinyl)-6-aminohexanoyl-Asp-Val-Pro-Asp-6-aminohexanoyl-N6-[methyl red]-Lys-[N-(6-aminohexyl)-Gly]8-N2-(6-aminohexyl)-Gly-NH2
pH and temperature not specified in the publication
0.0018
N-(5(6)-carboxyfluoresceinyl)-6-aminohexanoyl-Asp-Val-Val-Asp-6-aminohexanoyl-N6-[methyl red]-Lys-[N-(6-aminohexyl)-Gly]8-N2-(6-aminohexyl)-Gly-NH2
pH and temperature not specified in the publication
0.0048
acetyl-L-Asp-L-Glu-L-Val-L-Asp-7-amido-4-methylcoumarin
mutant DELTA176-181, pH 4.75, 37°C
0.0088
acetyl-L-Asp-L-Glu-L-Val-L-Asp-7-amido-4-methylcoumarin
mutant DELTA176-181, pH 7.2, 37°C
0.0122
acetyl-L-Asp-L-Glu-L-Val-L-Asp-7-amido-4-methylcoumarin
wild-type, pH 4.75, 37°C
0.0138
acetyl-L-Asp-L-Glu-L-Val-L-Asp-7-amido-4-methylcoumarin
wild-type, pH 7.2, 37°C
0.0163
acetyl-L-Asp-L-Glu-L-Val-L-Asp-7-amido-4-methylcoumarin
mutant D179A, pH 4.75, 37°C
0.0335
acetyl-L-Asp-L-Glu-L-Val-L-Asp-7-amido-4-methylcoumarin
mutant D179A, pH 7.2, 37°C
0.002
benzoyl-L-Asp-L-Glu-L-Val-L-Asp-7-amido-4-methylcoumarin
mutant DELTA176-181, pH 4.75, 37°C
0.0069
benzoyl-L-Asp-L-Glu-L-Val-L-Asp-7-amido-4-methylcoumarin
mutant DELTA176-181, pH 7.2, 37°C
0.008
benzoyl-L-Asp-L-Glu-L-Val-L-Asp-7-amido-4-methylcoumarin
wild-type, pH 4.75, 37°C
0.0097
benzoyl-L-Asp-L-Glu-L-Val-L-Asp-7-amido-4-methylcoumarin
wild-type, pH 7.2, 37°C
0.013
benzoyl-L-Asp-L-Glu-L-Val-L-Asp-7-amido-4-methylcoumarin
mutant D179A, pH 4.75, 37°C
0.0255
benzoyl-L-Asp-L-Glu-L-Val-L-Asp-7-amido-4-methylcoumarin
mutant D179A, pH 7.2, 37°C
Please wait a moment until the data is sorted. This message will disappear when the data is sorted.
TURNOVER NUMBER [1/s]
SUBSTRATE
ORGANISM
UNIPROT
COMMENTARY
LITERATURE
IMAGE
0.0217
N-(5(6)-carboxyfluoresceinyl)-6-aminohexanoyl-Asp-Ala-Pro-Asp-6-aminohexanoyl-N6-[methyl red]-Lys-[N-(6-aminohexyl)-Gly]8-N2-(6-aminohexyl)-Gly-NH2
pH and temperature not specified in the publication
0.0183
N-(5(6)-carboxyfluoresceinyl)-6-aminohexanoyl-Asp-Ala-Val-Asp-6-aminohexanoyl-N6-[methyl red]-Lys-[N-(6-aminohexyl)-Gly]8-N2-(6-aminohexyl)-Gly-NH2
pH and temperature not specified in the publication
0.017
N-(5(6)-carboxyfluoresceinyl)-6-aminohexanoyl-Asp-Asn-Pro-Asp-6-aminohexanoyl-N6-[methyl red]-Lys-[N-(6-aminohexyl)-Gly]8-N2-(6-aminohexyl)-Gly-NH2
pH and temperature not specified in the publication
0.013
N-(5(6)-carboxyfluoresceinyl)-6-aminohexanoyl-Asp-Asn-Val-Asp-6-aminohexanoyl-N6-[methyl red]-Lys-[N-(6-aminohexyl)-Gly]8-N2-(6-aminohexyl)-Gly-NH2
pH and temperature not specified in the publication
0.015
N-(5(6)-carboxyfluoresceinyl)-6-aminohexanoyl-Asp-Glu-Val-Asp-6-aminohexanoyl-N6-[methyl red]-Lys-[N-(6-aminohexyl)-Gly]8-N2-(6-aminohexyl)-Gly-NH2
pH and temperature not specified in the publication
0.00917
N-(5(6)-carboxyfluoresceinyl)-6-aminohexanoyl-Asp-Gly-Pro-Asp-6-aminohexanoyl-N6-[methyl red]-Lys-[N-(6-aminohexyl)-Gly]8-N2-(6-aminohexyl)-Gly-NH2
pH and temperature not specified in the publication
0.0083
N-(5(6)-carboxyfluoresceinyl)-6-aminohexanoyl-Asp-Gly-Val-Asp-6-aminohexanoyl-N6-[methyl red]-Lys-[N-(6-aminohexyl)-Gly]8-N2-(6-aminohexyl)-Gly-NH2
pH and temperature not specified in the publication
0.023
N-(5(6)-carboxyfluoresceinyl)-6-aminohexanoyl-Asp-Leu-Pro-Asp-6-aminohexanoyl-N6-[methyl red]-Lys-[N-(6-aminohexyl)-Gly]8-N2-(6-aminohexyl)-Gly-NH2
pH and temperature not specified in the publication
0.015
N-(5(6)-carboxyfluoresceinyl)-6-aminohexanoyl-Asp-Leu-Val-Asp-6-aminohexanoyl-N6-[methyl red]-Lys-[N-(6-aminohexyl)-Gly]8-N2-(6-aminohexyl)-Gly-NH2
pH and temperature not specified in the publication
0.028
N-(5(6)-carboxyfluoresceinyl)-6-aminohexanoyl-Asp-Val-Pro-Asp-6-aminohexanoyl-N6-[methyl red]-Lys-[N-(6-aminohexyl)-Gly]8-N2-(6-aminohexyl)-Gly-NH2
pH and temperature not specified in the publication
0.023
N-(5(6)-carboxyfluoresceinyl)-6-aminohexanoyl-Asp-Val-Val-Asp-6-aminohexanoyl-N6-[methyl red]-Lys-[N-(6-aminohexyl)-Gly]8-N2-(6-aminohexyl)-Gly-NH2
pH and temperature not specified in the publication
additional information
acetyl-L-Asp-L-Glu-L-Val-L-Asp-7-amido-4-methylcoumarin
wild-type, pH 7.2, 37°C
0.08
acetyl-L-Asp-L-Glu-L-Val-L-Asp-7-amido-4-methylcoumarin
mutant DELTA176-181, pH 4.75, 37°C
0.33
acetyl-L-Asp-L-Glu-L-Val-L-Asp-7-amido-4-methylcoumarin
wild-type, pH 4.75, 37°C
1.37
acetyl-L-Asp-L-Glu-L-Val-L-Asp-7-amido-4-methylcoumarin
mutant D179A, pH 4.75, 37°C
1.54
acetyl-L-Asp-L-Glu-L-Val-L-Asp-7-amido-4-methylcoumarin
mutant DELTA176-181, pH 7.2, 37°C
3.5
acetyl-L-Asp-L-Glu-L-Val-L-Asp-7-amido-4-methylcoumarin
mutant D179A, pH 7.2, 37°C
6.01
acetyl-L-Asp-L-Glu-L-Val-L-Asp-7-amido-4-methylcoumarin
wild-type, pH 7.2, 37°C
19.56
acetyl-L-Asp-L-Glu-L-Val-L-Asp-7-amido-4-methylcoumarin
mutant D179A, pH 7.2, 37°C
0.03 - 0.55
benzoyl-L-Asp-L-Glu-L-Val-L-Asp-7-amido-4-methylcoumarin
wild-type, pH 7.2, 37°C
0.06
benzoyl-L-Asp-L-Glu-L-Val-L-Asp-7-amido-4-methylcoumarin
mutant DELTA176-181, pH 4.75, 37°C
0.16
benzoyl-L-Asp-L-Glu-L-Val-L-Asp-7-amido-4-methylcoumarin
wild-type, pH 4.75, 37°C
1.1
benzoyl-L-Asp-L-Glu-L-Val-L-Asp-7-amido-4-methylcoumarin
mutant D179A, pH 4.75, 37°C
1.1
benzoyl-L-Asp-L-Glu-L-Val-L-Asp-7-amido-4-methylcoumarin
mutant D179A, pH 7.2, 37°C
1.43
benzoyl-L-Asp-L-Glu-L-Val-L-Asp-7-amido-4-methylcoumarin
mutant DELTA176-181, pH 7.2, 37°C
7.08
benzoyl-L-Asp-L-Glu-L-Val-L-Asp-7-amido-4-methylcoumarin
wild-type, pH 7.2, 37°C
19.04
benzoyl-L-Asp-L-Glu-L-Val-L-Asp-7-amido-4-methylcoumarin
mutant D179A, pH 7.2, 37°C
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kcat/KM VALUE [1/mMs-1]
SUBSTRATE
ORGANISM
UNIPROT
COMMENTARY
LITERATURE
IMAGE
56.7
N-(5(6)-carboxyfluoresceinyl)-6-aminohexanoyl-Asp-Ala-Pro-Asp-6-aminohexanoyl-N6-[methyl red]-Lys-[N-(6-aminohexyl)-Gly]8-N2-(6-aminohexyl)-Gly-NH2
pH and temperature not specified in the publication
11.7
N-(5(6)-carboxyfluoresceinyl)-6-aminohexanoyl-Asp-Ala-Val-Asp-6-aminohexanoyl-N6-[methyl red]-Lys-[N-(6-aminohexyl)-Gly]8-N2-(6-aminohexyl)-Gly-NH2
pH and temperature not specified in the publication
20
N-(5(6)-carboxyfluoresceinyl)-6-aminohexanoyl-Asp-Asn-Pro-Asp-6-aminohexanoyl-N6-[methyl red]-Lys-[N-(6-aminohexyl)-Gly]8-N2-(6-aminohexyl)-Gly-NH2
pH and temperature not specified in the publication
33.3
N-(5(6)-carboxyfluoresceinyl)-6-aminohexanoyl-Asp-Asn-Val-Asp-6-aminohexanoyl-N6-[methyl red]-Lys-[N-(6-aminohexyl)-Gly]8-N2-(6-aminohexyl)-Gly-NH2
pH and temperature not specified in the publication
25
N-(5(6)-carboxyfluoresceinyl)-6-aminohexanoyl-Asp-Glu-Val-Asp-6-aminohexanoyl-N6-[methyl red]-Lys-[N-(6-aminohexyl)-Gly]8-N2-(6-aminohexyl)-Gly-NH2
pH and temperature not specified in the publication
13.3
N-(5(6)-carboxyfluoresceinyl)-6-aminohexanoyl-Asp-Gly-Pro-Asp-6-aminohexanoyl-N6-[methyl red]-Lys-[N-(6-aminohexyl)-Gly]8-N2-(6-aminohexyl)-Gly-NH2
pH and temperature not specified in the publication
28.3
N-(5(6)-carboxyfluoresceinyl)-6-aminohexanoyl-Asp-Gly-Val-Asp-6-aminohexanoyl-N6-[methyl red]-Lys-[N-(6-aminohexyl)-Gly]8-N2-(6-aminohexyl)-Gly-NH2
pH and temperature not specified in the publication
96.7
N-(5(6)-carboxyfluoresceinyl)-6-aminohexanoyl-Asp-Leu-Pro-Asp-6-aminohexanoyl-N6-[methyl red]-Lys-[N-(6-aminohexyl)-Gly]8-N2-(6-aminohexyl)-Gly-NH2
pH and temperature not specified in the publication
20
N-(5(6)-carboxyfluoresceinyl)-6-aminohexanoyl-Asp-Leu-Val-Asp-6-aminohexanoyl-N6-[methyl red]-Lys-[N-(6-aminohexyl)-Gly]8-N2-(6-aminohexyl)-Gly-NH2
pH and temperature not specified in the publication
135
N-(5(6)-carboxyfluoresceinyl)-6-aminohexanoyl-Asp-Val-Pro-Asp-6-aminohexanoyl-N6-[methyl red]-Lys-[N-(6-aminohexyl)-Gly]8-N2-(6-aminohexyl)-Gly-NH2
pH and temperature not specified in the publication
13.3
N-(5(6)-carboxyfluoresceinyl)-6-aminohexanoyl-Asp-Val-Val-Asp-6-aminohexanoyl-N6-[methyl red]-Lys-[N-(6-aminohexyl)-Gly]8-N2-(6-aminohexyl)-Gly-NH2
pH and temperature not specified in the publication
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Ki VALUE [mM]
INHIBITOR
ORGANISM
UNIPROT
COMMENTARY
LITERATURE
IMAGE
0.012
(R)-5-[1-[2-(anilinomethyl)pyrrolidinyl]sulfonyl]isatin
pH 7.5, 30°C
0.0000012
(S)-1-benzyl-5-[1-[2-(phenoxymethyl)pyrrolidinyl]sulfonyl]isatin
pH 7.5, 30°C
0.000019
(S)-1-[(tert-butyloxycarbonyl)methyl]-5-[1-[2-(phenoxymethyl)pyrrolidinyl]sulfonyl]isatin
pH 7.5, 30°C
0.00006
(S)-5-[1-(2-methoxymethyl)pyrrolidinylsulfonyl]isatin
pH 7.5, 30°C
0.000015
(S)-5-[1-[2-(phenoxymethyl)pyrrolidinyl]sulfonyl]isatin
pH 7.5, 30°C
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IC50 VALUE [mM]
INHIBITOR
ORGANISM
UNIPROT
COMMENTARY
LITERATURE
IMAGE
0.018
(R)-5-[1-(2-methoxymethyl)pyrrolidinylsulfonyl]isatin
Homo sapiens
IC50: 0.018 mM
0.0055
(R)-5-[1-[2-(anilinomethyl)pyrrolidinyl]sulfonyl]isatin
Homo sapiens
IC50: 0.0055 mM
0.000044
(S)-(+)-5-[1-[2-(thiophenoxymethyl)pyrrolidinyl]sulfonyl]isatin
Homo sapiens
IC50: 44 nM
0.0000042
(S)-1-(4-pyridinylmethyl)-5-[1-[2-(phenoxymethyl)pyrrolidinyl]sulfonal]isatin
Homo sapiens
IC50: 4.2 nM
0.00017
(S)-1-(carboxymethyl)-5-[1-[2-(phenoxymethyl)pyrrolidinyl]sulfonyl]isatin
Homo sapiens
IC50: 170 nM
0.0000052
(S)-1-(cyclohexylmethyl)-5-[1-[2-(phenoxymethyl)pyrrolidinyl]sulfonal]isatin
Homo sapiens
IC50: 5.2 nM
0.0000046
(S)-1-allyl-5-[1-[2-(phenoxymethyl)pyrrolidinyl]sulfonyl]isatin
Homo sapiens
IC50: 4.6 nM
0.0000025
(S)-1-benzyl-5-[1-[2-(phenoxymethyl)pyrrolidinyl]sulfonyl]isatin
Homo sapiens
IC50: 2.5 nM
0.00003
(S)-1-methyl-5-[1-[2-(phenoxymethyl)pyrrolidinyl]sulfonyl]isatin
Homo sapiens
IC50: 30 nM
0.0000031
(S)-1-[(tert-butyloxycarbonyl)methyl]-5-[1-[2-(phenoxymethyl)pyrrolidinyl]sulfonyl]isatin
Homo sapiens
IC50: 3.1 nM
0.00012
(S)-5-[1-(2-methoxymethyl)pyrrolidinylsulfonyl]isatin
Homo sapiens
IC50: 120 nM
0.00017
(S)-5-[1-[(2-methoxycarbonyl)pyrrolidinyl]sulfonyl]isatin
Homo sapiens
IC50: 170 nM
0.00007
(S)-5-[1-[(2-tert-butoxycarbonyl)pyrrolidinyl]sulfonyl]isatin
Homo sapiens
IC50: 70 nM
0.000031
(S)-5-[1-[2-(anilinomethyl)pyrrolidinyl]sulfonyl]isatin
Homo sapiens
IC50: 31 nM
0.000044
(S)-5-[1-[2-(phenoxymethyl)pyrrolidinyl]sulfonyl]isatin
Homo sapiens
IC50: 44 nM
0.00014
(S)-5-[1-[2-(phenylaminocarbonyl)pyrrolidinyl]sulfonyl]isatin
Homo sapiens
IC50: 140 nM
0.00041
(S)-5-[1-[[2-(dimethylamino)carbonyl]pyrrolidinyl]sulfonyl]isatin
Homo sapiens
IC50: 410 nM
0.04
N-benzyloxycarbonyl-Val-Ala-Asp(O-Me) fluoromethyl ketone
Homo sapiens
pH 7.4, 37°C
0.04474
N-[(2-fluorophenyl)methyl]-N-methyl-2,3-dioxo-1-(prop-2-yn-1-yl)-2,3-dihydro-1H-indole-5-sulfonamide
Homo sapiens
37°C, pH 7.4
0.06096
N-[(2-fluorophenyl)methyl]-N-methyl-2,3-dioxo-2,3-dihydro-1H-indole-5-sulfonamide
Homo sapiens
37°C, pH 7.4
0.05149
N-[(3-fluorophenyl)methyl]-N-methyl-2,3-dioxo-1-(prop-2-yn-1-yl)-2,3-dihydro-1H-indole-5-sulfonamide
Homo sapiens
37°C, pH 7.4
0.02508
N-[(3-fluorophenyl)methyl]-N-methyl-2,3-dioxo-2,3-dihydro-1H-indole-5-sulfonamide
Homo sapiens
37°C, pH 7.6
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ORGANISM
COMMENTARY
LITERATURE
UNIPROT
SEQUENCE DB
SOURCE
-
SwissProt
brenda
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SOURCE TISSUE
ORGANISM
UNIPROT
COMMENTARY
LITERATURE
SOURCE
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GENERAL INFORMATION
ORGANISM
UNIPROT
COMMENTARY
LITERATURE
physiological function
cleavage by caspase-3 is a crucial upstream event associated with Tau self-assembly leading to Alzheimer's Disease pathogenesis
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UNIPROT
ENTRY NAME
ORGANISM
NO. OF AA
NO. OF TRANSM. HELICES
MOLECULAR WEIGHT[Da]
SOURCE
SEQUENCE
LOCALIZATION PREDICTION
The reliability class of the localization prediction ranges from 1 (very reliable) to 5 (not reliable).
The reliability class of the localization prediction ranges from 1 (very reliable) to 5 (not reliable). CASP3_HUMAN
277
0
31608
Swiss-Prot
other Location (Reliability: 1)
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PDB
SCOP
CATH
UNIPROT
ORGANISM
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MOLECULAR WEIGHT
ORGANISM
UNIPROT
COMMENTARY
LITERATURE
additional information
additional information
full-length proCPP32 has a molecular weight of 32000-33000 Da
additional information
-
full-length proCPP32 has a molecular weight of 32000-33000 Da
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SUBUNIT
ORGANISM
UNIPROT
COMMENTARY
LITERATURE
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POSTTRANSLATIONAL MODIFICATION
ORGANISM
UNIPROT
COMMENTARY
LITERATURE
proteolytic modification
both Mch4 and granzyme B cleave recombinant proCPP32 at a conserved IXXD-S sequence to produce the large and small subunits of the active protease. Granzyme B cleaves at Asp175 to generate the small C-terminal subunit, 12000 Da, and te large N-terminal subunit. Cleavage of the prodomain is an autocatalytic activity of the activated CPP32
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CRYSTALLIZATION (Commentary)
ORGANISM
UNIPROT
LITERATURE
in complex with inhibitors acetyl-Asp-Glu-Val-Asp-aldehyde, acetyl-Val-Asp-Val-Ala-Asp-aldehyde, acetyl-Asp-Met-Gln-Asp-aldehyde
recombinant enzyme in complex with inhibitors Ac-IEPD-Cho, Ac-WEHD-Cho, Ac-YVADCho, and Boc-D(OMe)-fluoromethyl ketone, caspase-3 is incubated at room temperature with the inhibitor at 10 to 20fold molar excess, followed by crystallization via the hanging-drop vapor diffusion method, 0.001 ml of 4 mg/ml protein in solution is mixed with an equal volume of mother liquid containing 100 mM sodium citrate, 5% glycerol, 10 mM DTT, and 14-18% PEG 6000, pH 6.5, 24 h at room temperature, X-ray diffraction structure determination and analysis at 1.9-2.6 A resolution, molecular replacement, modelling, overview
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PROTEIN VARIANTS
ORGANISM
UNIPROT
COMMENTARY
LITERATURE
D179A
increase both in kcat- and KM-value. D179 is involved in substrate recognition
additional information
additional information
caspase-3 knockout by shRNA, generation of double knockdown cells lacking caspase-3 and caspase-7, EC 3.4.22.60, activity. Generation of caspase-7-based chimeric constructs with various regions of caspase-3, EC 3.4.22.56
additional information
-
caspase-3 knockout by shRNA, generation of double knockdown cells lacking caspase-3 and caspase-7, EC 3.4.22.60, activity. Generation of caspase-7-based chimeric constructs with various regions of caspase-3, EC 3.4.22.56
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PURIFICATION (Commentary)
ORGANISM
UNIPROT
LITERATURE
recombinant enzyme from Escherichia coli by nickel affinity chromatography, ion exchange chromatography, and gel filtration
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CLONED (Commentary)
ORGANISM
UNIPROT
LITERATURE
expression of FLAG-tagged caspase-3 in DKD cells. Simultaneous expression of HA-procaspase-3 and HA-procaspase-7, EC 3.4.22.60, in DKD HeLa cells together with FLAG-caspase-3 or FLAG-caspase-7. HA-procaspase-3 is coimmunoprecipitated with FLAG-procaspase-3 but not with FLAG-procaspase-7. Similarly, HA-procaspase-7 is co-immunoprecipitated with FLAG-procaspase-7 but not with FLAG-procaspase-3
the full-length caspase-3 gene containing an N-terminal 6His-tag is expressed in Escherichia coli
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REF.
AUTHORS
TITLE
JOURNAL
VOL.
PAGES
YEAR
ORGANISM (UNIPROT)
PUBMED ID
SOURCE
Fernandes-Alnemri, T.; Armstrong, R.C.; Krebs, J.F.; Srinivasula, S.M.; Wang, L.; Bullrich, F.; Fritz, L.C.; Trapani, J.A.; Tomaselli, K.J.; Litwack, G.; Alnemri, E.S.
In vitro activation of CPP32 and Mch3 by Mch4, a novel human apoptotic cysteine protease containing two FADD-like domains
Proc. Natl. Acad. Sci. USA
93
7464-7469
1996
Homo sapiens (P42574), Homo sapiens
brenda
Fernandes-Alnemri, T.; Litwack, G.; Alnemri E.S.
CPP32, a novel human apoptotic protein with homology to Caenorhabditis elegans cell death protein Ced-3 and mammalian interleukin-1 beta-converting enzyme
J. Biol. Chem.
269
30761-30764
1994
Homo sapiens (P42574), Homo sapiens
brenda
Tewari, M.; Quan, L.T.; O'Rourke, K.; Desnoyers, S.; Zeng, Z.; Beidler, D.R.; Poirier, G.G.; Salvesen, G.S.; Dixit, V.M.
Yama/CPP32 beta, a mammalian homolog of CED-3, is a CrmA-inhibitable protease that cleaves the death substrate poly(ADP-ribose) polymerase
Cell
81
801-809
1995
Homo sapiens (P42574)
brenda
Lee, D.; Long, S.A.; Adams, J.L.; Chan, G.; et al.
Potent and selective nonpeptide inhibitors of caspases 3 and 7 inhibit apoptosis and maintain cell functionality
J. Biol. Chem.
275
16007-16014
2000
Homo sapiens (P42574), Homo sapiens
brenda
Goldberg, Y.P.; Nicholson, D.W.; Rasper, D.M.; Kalchman, M.A.; Koide, H.B.; et al.
Cleavage of huntingtin by apopain, a proapoptotic cysteine protease, is modulated by the polyglutamine tract
Nat. Genet.
13
442-449
1996
Homo sapiens (P42574), Homo sapiens
brenda
Ganesan, R.; Mittl, P.R.; Jelakovic, S.; Gruetter, M.G.
Extended substrate recognition in caspase-3 revealed by high resolution X-ray structure analysis
J. Mol. Biol.
359
1378-1388
2006
Homo sapiens (P42574)
brenda
Fang, B.; Boross, P.I.; Tozser, J.; Weber, I.T.
Structural and kinetic analysis of caspase-3 reveals role for S5 binding site in substrate recognition
J. Mol. Biol.
360
654-666
2006
Homo sapiens (P42574), Homo sapiens
brenda
Fang, B.; Fu, G.; Agniswamy, J.; Harrison, R.W.; Weber, I.T.
Caspase-3 binds diverse P4 residues in peptides as revealed by crystallography and structural modeling
Apoptosis
14
741-752
2009
Homo sapiens (P42574)
brenda
Nakatsumi, H.; Yonehara, S.
Identification of functional regions defining different activity in caspase-3 and caspase-7 within cells
J. Biol. Chem.
285
25418-25425
2010
Homo sapiens (P42574), Homo sapiens
brenda
Eda, S.R.; Veeramachaneni, G.K.; Bondili, J.S.; Jinka, R.
Screening of caspase-3 inhibitors from natural molecule database using e-pharmacophore and docking studies
Bioinformation
15
240-245
2019
Homo sapiens (P42574)
brenda
Sandhu, P.; Naeem, M.M.; Lu, C.; Kumarathasan, P.; Gomes, J.; Basak, A.
Ser422 phosphorylation blocks human Tau cleavage by caspase-3 Biochemical implications to Alzheimers Disease
Bioorg. Med. Chem. Lett.
27
642-652
2017
Homo sapiens (P42574), Homo sapiens
brenda
Lin, B.; Zhu, M.; Wang, W.; Li, W.; Dong, X.; Chen, Y.; Lu, Y.; Guo, J.; Li, M.
Structural basis for alpha fetoprotein-mediated inhibition of caspase-3 activity in hepatocellular carcinoma cells
Int. J. Cancer
141
1413-1421
2017
Homo sapiens (P42574), Homo sapiens
brenda
Tavari, M.; Malan, S.; Joubert, J.
Design, synthesis, biological evaluation and docking studies of sulfonyl isatin derivatives as monoamine oxidase and caspase-3 inhibitors
MedChemComm
7
1628-1639
2016
Homo sapiens (P42574)
-
brenda
Perez-Lopez, A.M.; Soria-Gila, M.L.; Marsden, E.R.; Lilienkampf, A.; Bradley, M.
Fluorogenic substrates for in situ monitoring of caspase-3 activity in live cells
PLoS ONE
11
e0153209
2016
Homo sapiens (P42574)
brenda
EXTERNAL LINKS (specific for EC-Number 3.4.22.56)
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