Reference on EC 3.4.11.10 - bacterial leucyl aminopeptidase and Organism(s) Vibrio proteolyticus and UniProt Accession Q01693
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AUTHORS
TITLE
JOURNAL
VOL.
PAGES
YEAR
ORGANISM (UNIPROT)
PUBMED ID
SOURCE
Baker, J.O.; Prescott, J.M.
A transition-state-analog inhibitor influences zinc-binding by Aeromonas aminopeptidase
Biochem. Biophys. Res. Commun.
130
1154-1160
1985
Vibrio proteolyticus
Wilkes, S.H.; Prescott, J.M.
The slow, tight binding of bestatin and amastatin to aminopeptidases
J. Biol. Chem.
260
13154-13162
1985
Vibrio proteolyticus
Prescott, J.M.; Wagner, F.W.; Holmquist, B.; Vallee, B.L.
Spectral and kinetic studies of metal-substituted Aeromonas aminopeptidase: nonidentical, interacting metal-binding sites
Biochemistry
24
5350-5356
1985
Vibrio proteolyticus
Wilkes, S.H.; Prescott, J.M.
Stereospecificity of amino acid hydroxamate inhibition of aminopeptidases
J. Biol. Chem.
258
13517-13521
1983
Vibrio proteolyticus
Prescott, J.M.; Wagner, F.W.; Holmquist, B.; Vallee, B.L.
One hundred fold increased activity of Aeromonas aminopeptidase by sequential substitutions with Ni(II) or Cu(II) followed by zinc
Biochem. Biophys. Res. Commun.
114
646-652
1983
Vibrio proteolyticus
Baker, J.O.; Wilkes, S.H.; Bayliss, M.E.; Prescott, J.M.
Hydroxamates and aliphatic boronic acids: marker inhibitors for aminopeptidase
Biochemistry
22
2098-2103
1983
Vibrio proteolyticus
Prescott, J.M.; Wilkes, S.H.
Aeromonas aminopeptidase
Methods Enzymol.
45
530-543
1976
Vibrio proteolyticus
Kettner, C.; Glover, G.I.; Prescott, J.M.
Kinetics of inhibition of Aeromonas aminopeptidase by leucine methyl ketone derivatives
Arch. Biochem. Biophys.
165
739-743
1974
Vibrio proteolyticus
Kettner, C.; Rodriguez-Absi, J.; Glover, G.I.; Prescott, J.M.
The purification of Aeromonas aminopeptidase by affinity chromatography
Arch. Biochem. Biophys.
162
56-63
1974
Vibrio proteolyticus
Wagner, F.W.; Wilkes, S.H.; Prescott, J.M.
Specificity of Aeromonas aminopeptidase toward amino acid amides and dipeptides
J. Biol. Chem.
247
1208-1210
1972
Vibrio proteolyticus
Prescott, J.M.; Wilkes, S.H.; Wagner, F.W.; Wilson, K.J.
Aeromonas aminopeptidase. Improved isolation and some physical properties
J. Biol. Chem.
246
1756-1764
1971
Vibrio proteolyticus
Prescott, J.M.; Wilkes, S.H.
Aeromonas aminopeptidase: purification and some general properties
Arch. Biochem. Biophys.
117
328-336
1966
Vibrio proteolyticus
Maekinen, K.K.; Maekinen, P.L.; Wilkes, S.H.; Bayliss, M.E.; Prescott, J.M.
Chemical modification of Aeromonas aminopeptidase. Evidence for the involvement of tyrosyl and carboxyl groups in the activity of the enzyme
Eur. J. Biochem.
128
257-265
1982
Vibrio proteolyticus
Maekinen, K.K.; Maekinen, P.L.; Wilkes, S.H.; Bayliss, M.E.; Prescott, J.M.
Photochemical inactivation of Aeromonas aminopeptidase by 2,3-butanedione
J. Biol. Chem.
257
1765-1772
1982
Vibrio proteolyticus
Wilkes, S.H.; Bayliss, M.E.; Prescott, J.M.
Specificity of aeromonas aminopeptidase toward oligopeptides and polypeptides
Eur. J. Biochem.
34
459-466
1973
Vibrio proteolyticus
Schalk, C.; Remy, J.M.; Chevrier, B.; Moras, D.; Tarnus, C.
Rapid purification of the Aeromonas proteolytica aminopeptidase: crystallization and preliminary X-ray data
Arch. Biochem. Biophys.
294
91-97
1992
Vibrio proteolyticus
Bennett, B.; Holz, R.C.
Spectroscopically distinct cobalt(II) sites in heterodimetallic forms of the aminopeptidase from Aeromonas proteolytica: characterization of substrate binding
Biochemistry
36
9837-9846
1997
Vibrio proteolyticus
Chevrier, B.; D'Orchymont, H.; Schalk, C.; Moras, D.
The structure of the Aeromonas proteolytica aminopeptidase complexed with a hydroxamate inhibitor. Involvement in catalysis of Glu151 and two zinc ions of the co-catalytic unit
Eur. J. Biochem.
237
393-398
1996
Vibrio proteolyticus
De Paola, C.C.; Bennett, B.; Holz, R.C.; Ringe, D.; Petsko, G.A.
1-Butaneboronic acid binding to Aeromonas proteolytica aminopeptidase: a case of arrested development
Biochemistry
38
9048-9053
1999
Vibrio proteolyticus (Q01693)
Ustynyuk, L.; Bennett, B.; Edwards, T.; Holz, R.C.
Inhibition of the aminopeptidase from Aeromonas proteolytica by aliphatic alcohols. Characterization of the hydrophobic substrate recognition site
Biochemistry
38
11433-11439
1999
Vibrio proteolyticus
Huntington, K.M.; Bienvenue, D.L.; Wei, Y.; Bennett, B.; Holz, R.C.; Pei, D.
Slow-binding inhibition of the aminopeptidase from Aeromonas proteolytica by peptide thiols: synthesis and spectroscopic characterization
Biochemistry
38
15587-15596
1999
Vibrio proteolyticus
Stamper, C.; Bennett, B.; Edwards, T.; Holz, R.C.; Ringe, D.; Petsko, G.
Inhibition of the aminopeptidase from Aeromonas proteolytica by L-leucinephosphonic acid. Spectroscopic and crystallographic characterization of the transition state of peptide hydrolysis
Biochemistry
40
7035-7046
2001
Vibrio proteolyticus (Q01693)
Bienvenue, D.L.; Gilner, D.; Holz, R.C.
Hydrolysis of thionopeptides by the aminopeptidase from Aeromonas proteolytica: insight into substrate binding
Biochemistry
41
3712-3719
2002
Vibrio proteolyticus
Bienvenue, D.L.; Mathew, R.S.; Ringe, D.; Holz, R.C.
The aminopeptidase from Aeromonas proteolytica can function as an esterase
J. Biol. Inorg. Chem.
7
129-135
2002
Vibrio proteolyticus
Desmarais, W.T.; Bienvenue, D.L.; Bzymek, K.P.; Holz, R.C.; Petsko, G.A.; Ringe, D.
The 1.20 A resolution crystal structure of the aminopeptidase from Aeromonas proteolytica complexed with tris: a tale of buffer inhibition
Structure
10
1063-1072
2002
Vibrio proteolyticus (Q01693)
Jankiewicz, U.; Bielawski, W.
The properties and functions of bacterial aminopeptidases
Acta Microbiol. Pol.
52
217-231
2003
Brevibacterium linens, Brevibacterium linens SR3, Escherichia coli, Lactococcus sp., Mycoplasma salivarium, Pseudomonas aeruginosa, Pseudomonas putida, Salmonella enterica subsp. enterica serovar Typhimurium, Vibrio proteolyticus
Schuerer, G.; Lanig, H.; Clark, T.
Aeromonas proteolytica aminopeptidase: an investigation of the mode of action using a quantum mechanical/molecular mechanical approach
Biochemistry
43
5414-5427
2004
Vibrio proteolyticus (Q01693)
Bzymek, K.P.; Moulin, A.; Swierczek, S.I.; Ringe, D.; Petsko, G.A.; Bennett, B.; Holz, R.C.
Kinetic, spectroscopic, and X-ray crystallographic characterization of the functional E151H aminopeptidase from Aeromonas proteolytica
Biochemistry
44
12030-12040
2005
Vibrio proteolyticus (Q01693)
Bennett, B.
EPR of Co(II) as a structural and mechanistic probe of metalloprotein active sites: characterisation of an aminopeptidase
Curr. Top. Biophys.
26
49-57
2002
Vibrio proteolyticus
-
Chevrier, B.; D'Orchymont, H.
Vibrio aminopeptidase
Handbook of Proteolytic Enzymes (Barrett, J. ; Rawlings, N. D. ; Woessner, J. F. , eds)
1
963-965
2004
Vibrio proteolyticus
-
Bzymek, K.P.; Swierczek, S.I.; Bennett, B.; Holz, R.C.
Spectroscopic and thermodynamic characterization of the E151D and E151A altered leucine aminopeptidases from Aeromonas proteolytica
Inorg. Chem.
44
8574-8580
2005
Vibrio proteolyticus
Bienvenue, D.L.; Bennett, B.; Holz, R.C.
Inhibition of the aminopeptidase from Aeromonas proteolytica by L-leucinethiol: kinetic and spectroscopic characterization of a slow, tight-binding inhibitor-enzyme complex
J. Inorg. Biochem.
78
43-54
2000
Vibrio proteolyticus
Bzymek, K.P.; D'Souza, V.M.; Chen, G.; Campbell, H.; Mitchell, A.; Holz, R.C.
Function of the signal peptide and N- and C-terminal propeptides in the leucine aminopeptidase from Aeromonas proteolytica
Protein Expr. Purif.
37
294-305
2004
Vibrio proteolyticus (Q01693)
Kumar, A.; Periyannan, G.R.; Narayanan, B.; Kittell, A.W.; Kim, J.J.; Bennett, B.
Experimental evidence for a metallohydrolase mechanism in which the nucleophile is not delivered by a metal ion: EPR spectrokinetic and structural studies of aminopeptidase from Vibrio proteolyticus
Biochem. J.
403
527-536
2007
Vibrio proteolyticus (Q01693)
Albrecht, S.; Defoin, A.; Salomon, E.; Tarnus, C.; Wetterholm, A.; Haeggstroem, J.Z.
Synthesis and structure activity relationships of novel non-peptidic metallo-aminopeptidase inhibitors
Bioorg. Med. Chem.
14
7241-7257
2006
Vibrio proteolyticus
Chen, S.; Marino, T.; Fang, W.; Russo, N.; Himo, F.
Peptide hydrolysis by the binuclear zinc enzyme aminopeptidase from Aeromonas proteolytica: A density functional theory study
J. Phys. Chem. B
112
2494-2500
2008
Vibrio proteolyticus (Q01693)
Ataie, N.J.; Hoang, Q.Q.; Zahniser, M.P.; Tu, Y.; Milne, A.; Petsko, G.A.; Ringe, D.
Zinc coordination geometry and ligand binding affinity: the structural and kinetic analysis of the second-shell serine 228 residue and the methionine 180 residue of the aminopeptidase from Vibrio proteolyticus
Biochemistry
47
7673-7683
2008
Vibrio proteolyticus (Q01693)
Hartley, M.; Bennett, B.
Heterologous expression and purification of Vibrio proteolyticus (Aeromonas proteolytica) aminopeptidase: a rapid protocol
Protein Expr. Purif.
66
91-101
2009
Vibrio proteolyticus (Q01693)
Frey, S.T.; Guilmet, S.L.; Egan, R.G.; Bennett, A.; Soltau, S.R.; Holz, R.C.
Immobilization of the aminopeptidase from Aeromonas proteolytica on Mg2+/Al3+ layered double hydroxide particles
ACS Appl. Mater. Interfaces
2
2828-2832
2010
Vibrio proteolyticus
Albrecht, S.; Al-Lakkis-Wehbe, M.; Orsini, A.; Defoin, A.; Pale, P.; Salomon, E.; Tarnus, C.; Weibel, J.
Amino-benzosuberone: A novel warhead for selective inhibition of human aminopeptidase-N/CD13
Bioorg. Med. Chem.
19
1434-1449
2011
Vibrio proteolyticus
Perez-Sanchez, G.; Leal-Guadarrama, L.; Trelles, I.; Perez, N.; Medina-Rivero, E.
High-level production of a recombinant Vibrio proteolyticus leucine aminopeptidase and its use for N-terminal methionine excision from interferon alpha-2b
Process Biochem.
46
1825-1830
2011
Vibrio proteolyticus (Q01693)
-
Hanaya, K.; Suetsugu, M.; Saijo, S.; Yamato, I.; Aoki, S.
Potent inhibition of dinuclear zinc(II) peptidase, an aminopeptidase from Aeromonas proteolytica, by 8-quinolinol derivatives: inhibitor design based on Zn2+ fluorophores, kinetic, and X-ray crystallographic study
J. Biol. Inorg. Chem.
17
517-529
2012
Vibrio proteolyticus
