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Literature summary for 3.4.11.10 extracted from
- Hydroxamates and aliphatic boronic acids: marker inhibitors for aminopeptidase (1983), Biochemistry, 22, 2098-2103.
Inhibitors
| Inhibitors | Comment | Organism | Structure |
|---|---|---|---|
| 1-Butaneboronate | - |
Vibrio proteolyticus |  |
| Amino acid hydroxamates | - |
Vibrio proteolyticus | |
| additional information | multiple inhibition study with substrate analogs and transition state analogs | Vibrio proteolyticus |
Metals/Ions
| Metals/Ions | Comment | Organism | Structure |
|---|---|---|---|
| additional information | metal ion interacts directly with the substrate atoms, as shown by multiple inhibitor studies | Vibrio proteolyticus |
Natural Substrates/ Products (Substrates)
| Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| Peptides + H2O | Vibrio proteolyticus | - |
? | - |
? | |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Vibrio proteolyticus | - |
- |
- |
Substrates and Products (Substrate)
| Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| Peptides + H2O | - |
Vibrio proteolyticus | ? | - |
? | |
Ki Value [mM]
| Ki Value [mM] | Ki Value maximum [mM] | Inhibitor | Comment | Organism | Structure |
|---|---|---|---|---|---|
| 0.0027 | - |
1-Butaneboronate | - |
Vibrio proteolyticus | |
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