Information on EC 2.7.7.71 - D-glycero-alpha-D-manno-heptose 1-phosphate guanylyltransferase

for references in articles please use BRENDA:EC2.7.7.71
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The expected taxonomic range for this enzyme is: Aneurinibacillus thermoaerophilus

EC NUMBER
COMMENTARY hide
2.7.7.71
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RECOMMENDED NAME
GeneOntology No.
D-glycero-alpha-D-manno-heptose 1-phosphate guanylyltransferase
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REACTION
REACTION DIAGRAM
COMMENTARY hide
ORGANISM
UNIPROT
LITERATURE
D-glycero-alpha-D-manno-heptose 1-phosphate + GTP = GDP-D-glycero-alpha-D-manno-heptose + diphosphate
show the reaction diagram
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PATHWAY
BRENDA Link
KEGG Link
MetaCyc Link
GDP-D-glycero-alpha-D-manno-heptose biosynthesis
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Lipopolysaccharide biosynthesis
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SYSTEMATIC NAME
IUBMB Comments
GTP:D-glycero-alpha-D-manno-heptose 1-phosphate guanylyltransferase
The enzyme is involved in biosynthesis of GDP-D-glycero-alpha-D-manno-heptose, which is required for assembly of S-layer glycoprotein in some Gram-positive bacteria.
ORGANISM
COMMENTARY hide
LITERATURE
UNIPROT
SEQUENCE DB
SOURCE
DSM 10155
SwissProt
Manually annotated by BRENDA team
SUBSTRATE
PRODUCT                       
REACTION DIAGRAM
ORGANISM
UNIPROT
COMMENTARY
(Substrate) hide
LITERATURE
(Substrate)
COMMENTARY
(Product) hide
LITERATURE
(Product)
Reversibility
r=reversible
ir=irreversible
?=not specified
D-glycero-D-alpha-manno-heptose 1-phosphate + GTP
GDP-D-glycero-D-alpha-manno-heptose + diphosphate
show the reaction diagram
NATURAL SUBSTRATES
NATURAL PRODUCTS
REACTION DIAGRAM
ORGANISM
UNIPROT
COMMENTARY
(Substrate) hide
LITERATURE
(Substrate)
COMMENTARY
(Product) hide
LITERATURE
(Product)
REVERSIBILITY
r=reversible
ir=irreversible
?=not specified
D-glycero-D-alpha-manno-heptose 1-phosphate + GTP
GDP-D-glycero-D-alpha-manno-heptose + diphosphate
show the reaction diagram
Q9AGY6
the enzyme is involved in biosynthesis of GDP-D-glycero-D-manno-heptose, which is required for assembly of S-layer glycoprotein in Gram-positive bacteria
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Purification/COMMENTARY
ORGANISM
UNIPROT
LITERATURE
Cloned/COMMENTARY
ORGANISM
UNIPROT
LITERATURE
Show AA Sequence (352 entries)
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