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Information on EC 2.7.1.49 - hydroxymethylpyrimidine kinase

for references in articles please use BRENDA:EC2.7.1.49

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IUBMB Comments

CTP, UTP and GTP can act as donors.

The expected taxonomic range for this enzyme is: Bacteria, Archaea, Eukaryota

Synonyms
hmp kinase, hmppk, hmp-p kinase, sthmppk, tthmppk, hydroxymethylpyrimidine kinase, 4-amino-5-hydroxymethyl-2-methylpyrimidine kinase, 4-amino-5-hydroxymethyl-2-methylpyrimidine pyrophosphate kinase, more

REACTION
REACTION DIAGRAM
COMMENTARY hide
ORGANISM
UNIPROT
LITERATURE
ATP + 4-amino-5-hydroxymethyl-2-methylpyrimidine = ADP + 4-amino-2-methyl-5-(phosphooxymethyl)pyrimidine
show the reaction diagram
PATHWAY SOURCE
PATHWAYS
MetaCyc
hydroxymethylpyrimidine salvage, thiamine diphosphate salvage IV (yeast), thiamine phosphate formation from pyrithiamine and oxythiamine (yeast)