EC Number |
Inhibitors |
Structure |
---|
2.7.1.49 | (6R)-6-[(2E)-4-oxo-6-phenylhex-2-en-1-yl]-5,6-dihydro-2H-pyran-2-one |
lactone isolated from Cryptocarya rugulosa, covalent inhibition |
|
2.7.1.49 | (6R)-6-[(2E)-6-(4-ethynylphenyl)-4-oxohex-2-en-1-yl]-5,6-dihydro-2H-pyran-2-one |
derivative of a lactone isolated from Cryptocarya rugulosa, covalent inhibition |
|
2.7.1.49 | (6S)-6-[(2E)-6-(4-ethynylphenyl)-4-oxohex-2-en-1-yl]tetrahydro-2H-pyran-2-one |
derivative of a lactone isolated from Cryptocarya rugulosa, covalent inhibition |
|
2.7.1.49 | 2-methyl-4-amino-5-hydroxymethylpyrimidine |
competitive inhibition |
|
2.7.1.49 | more |
stable to treatment with p-hydroxymercuribenzoate |
|
2.7.1.49 | pyridoxine |
inhibits competitively the phosphorylation of 2-methyl-4-amino-5-hydroxymethylpyrimidine |
|
2.7.1.49 | rugulactone |
selectively modifies the enzyme not at the active site cysteine, but on a remote cysteine residue |
|