Reference on EC 2.1.1.356 - [histone H3]-lysine27 N-trimethyltransferase
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REF. 
AUTHORS
TITLE
JOURNAL
VOL.
PAGES
YEAR
ORGANISM (UNIPROT)
PUBMED ID
SOURCE
Qian, C.; Wang, X.; Manzur, K.; Sachchidanand, K.; Farooq, A.; Zeng, L.; Wang, R.; Zhou, M.M.
Structural insights of the specificity and catalysis of a viral histone H3 lysine 27 methyltransferase
J. Mol. Biol.
359
86-96
2006
Paramecium bursaria Chlorella virus 1
Joshi, P.; Carrington, E.A.; Wang, L.; Ketel, C.S.; Miller, E.L.; Jones, R.S.; Simon, J.A.
Dominant alleles identify SET domain residues required for histone methyltransferase of Polycomb repressive complex 2
J. Biol. Chem.
283
27757-27766
2008
Drosophila melanogaster
Kim, J.Y.; Kee, H.J.; Choe, N.W.; Kim, S.M.; Eom, G.H.; Baek, H.J.; Kook, H.; Kook, H.; Seo, S.B.
Multiple-myeloma-related WHSC1/MMSET isoform RE-IIBP is a histone methyltransferase with transcriptional repression activity
Mol. Cell. Biol.
28
2023-2034
2008
Homo sapiens
Stepanik, V.A.; Harte, P.J.
A mutation in the E(Z) methyltransferase that increases trimethylation of histone H3 lysine 27 and causes inappropriate silencing of active Polycomb target genes
Dev. Biol.
364
249-258
2012
Drosophila melanogaster
Gu, X.; Xu, T.; He, Y.
A histone H3 lysine-27 methyltransferase complex represses lateral root formation in Arabidopsis thaliana
Mol. Plant
7
977-988
2014
Arabidopsis thaliana (P93831)
Kisliouk, T.; Yosefi, S.; Meiri, N.
MiR-138 inhibits EZH2 methyltransferase expression and methylation of histone H3 at lysine 27, and affects thermotolerance acquisition
Eur. J. Neurosci.
33
224-235
2011
Gallus gallus (A0A1D5PN50)
Tachibana, M.; Sugimoto, K.; Fukushima, T.; Shinkai, Y.
Set domain-containing protein, G9a, is a novel lysine-preferring mammalian histone methyltransferase with hyperactivity and specific selectivity to lysines 9 and 27 of histone H3
J. Biol. Chem.
276
25309-25317
2001
Homo sapiens (Q96KQ7)
Li, J.; Wei, H.; Zhou, M.M.
Structure-guided design of a methyl donor cofactor that controls a viral histone H3 lysine 27 methyltransferase activity
J. Med. Chem.
54
7734-7738
2011
Paramecium bursaria Chlorella virus 1 (O41094)
Friedman, J.; Cho, W.K.; Chu, C.K.; Keedy, K.S.; Archin, N.M.; Margolis, D.M.; Karn, J.
Epigenetic silencing of HIV-1 by the histone H3 lysine 27 methyltransferase enhancer of Zeste 2
J. Virol.
85
9078-9089
2011
Human immunodeficiency virus 1
Boros, J.; Arnoult, N.; Stroobant, V.; Collet, J.F.; Decottignies, A.
Polycomb repressive complex 2 and H3K27me3 cooperate with H3K9 methylation to maintain heterochromatin protein 1alpha at chromatin
Mol. Cell. Biol.
34
3662-3674
2014
Mus musculus (Q61188), Mus musculus
Connolly, L.R.; Smith, K.M.; Freitag, M.
The Fusarium graminearum histone H3 K27 methyltransferase KMT6 regulates development and expression of secondary metabolite gene clusters
PLoS Genet.
9
e1003916
2013
Fusarium graminearum
McCabe, M.T.; Graves, A.P.; Ganji, G.; Diaz, E.; Halsey, W.S.; Jiang, Y.; Smitheman, K.N.; Ott, H.M.; Pappalardi, M.B.; Allen, K.E.; Chen, S.B.; Della Pietra, A.; Dul, E.; Hughes, A.M.; Gilbert, S.A.; Thrall, S.H.; Tummino, P.J.; Kruger, R.G.; Brandt, M.; Schwartz, B.; Creasy, C.L.
Mutation of A677 in histone methyltransferase EZH2 in human B-cell lymphoma promotes hypertrimethylation of histone H3 on lysine 27 (H3K27)
Proc. Natl. Acad. Sci. USA
109
2989-2994
2012
Homo sapiens (Q15910), Homo sapiens
Zhao, X.; Wang, Y.; Wang, Y.; Liu, Y.; Gao, S.
Histone methyltransferase TXR1 is required for both H3 and H3.3 lysine 27 methylation in the well-known ciliated protist Tetrahymena thermophila
Sci. China Life Sci.
60
264-270
2017
Tetrahymena thermophila (Q23QI3), Tetrahymena thermophila SB210 (Q23QI3)
Cao, R.; Wang, L.; Wang, H.; Xia, L.; Erdjument-Bromage, H.; Tempst, P.; Jones, R.; Zhang, Y.
Role of histone H3 lysine 27 methylation in polycomb-group silencing
Science
298
1039-1043
2002
Homo sapiens (Q15910)
Jiao, L.; Liu, X.
Structural basis of histone H3K27 trimethylation by an active polycomb repressive complex 2
Science
350
aac4383
2015
Thermochaetoides thermophila, Thermochaetoides thermophila DSM1495
Morishita, M.; Mevius, D.; Di Luccio, E.
In vitro histone lysine methylation by NSD1, NSD2/MMSET/WHSC1 and NSD3/WHSC1L
BMC Struct. Biol.
14
25
2014
Homo sapiens (O96028), Homo sapiens (Q9BZ95)
Shen, Y.; Morishita, M.; di Luccio, E.
High yield recombinant expression and purification of oncogenic NSD1, NSD2, and NSD3 with human influenza hemagglutinin tag
Protein Expr. Purif.
166
105506
2020
Homo sapiens (O96028)
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