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Literature summary for 2.1.1.356 extracted from

  • Connolly, L.R.; Smith, K.M.; Freitag, M.
    The Fusarium graminearum histone H3 K27 methyltransferase KMT6 regulates development and expression of secondary metabolite gene clusters (2013), PLoS Genet., 9, e1003916 .
    View publication on PubMedView publication on EuropePMC
Search for more literature for 2.1.1.356

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
3 S-adenosyl-L-methionine + a [histone H3]-L-lysine27 Fusarium graminearum overall reaction 3 S-adenosyl-L-homocysteine + a [histone H3]-N6,N6,N6-trimethyl-L-lysine27
-
 ?
S-adenosyl-L-methionine + a [histone H3]-L-lysine27 Fusarium graminearum
-
 S-adenosyl-L-homocysteine + a [histone H3]-N6-methyl-L-lysine27
-
 ?
S-adenosyl-L-methionine + a [histone H3]-N6,N6-dimethyl-L-lysine27 Fusarium graminearum
-
 S-adenosyl-L-homocysteine + a [histone H3]-N6,N6,N6-trimethyl-L-lysine27
-
 ?
S-adenosyl-L-methionine + a [histone H3]-N6-methyl-L-lysine27 Fusarium graminearum
-
 S-adenosyl-L-homocysteine + a [histone H3]-N6,N6-dimethyl-L-lysine27
-
 ?

Organism

Organism UniProt Comment Textmining
Fusarium graminearum
-
-
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
3 S-adenosyl-L-methionine + a [histone H3]-L-lysine27 overall reaction Fusarium graminearum 3 S-adenosyl-L-homocysteine + a [histone H3]-N6,N6,N6-trimethyl-L-lysine27
-
 ?
S-adenosyl-L-methionine + a [histone H3]-L-lysine27
-
 Fusarium graminearum S-adenosyl-L-homocysteine + a [histone H3]-N6-methyl-L-lysine27
-
 ?
S-adenosyl-L-methionine + a [histone H3]-N6,N6-dimethyl-L-lysine27
-
 Fusarium graminearum S-adenosyl-L-homocysteine + a [histone H3]-N6,N6,N6-trimethyl-L-lysine27
-
 ?
S-adenosyl-L-methionine + a [histone H3]-N6-methyl-L-lysine27
-
 Fusarium graminearum S-adenosyl-L-homocysteine + a [histone H3]-N6,N6-dimethyl-L-lysine27
-
 ?

Synonyms

Synonyms Comment Organism
histone H3 K27 methyltransferase
-
 Fusarium graminearum
KMT6
-
 Fusarium graminearum

General Information

General Information Comment Organism
malfunction enzyme mutants are sterile, have morphological defects, and are altered in pigment production Fusarium graminearum