Reference on EC 1.14.13.8 - flavin-containing monooxygenase and Organism(s) Mus musculus and UniProt Accession P50285
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AUTHORS
TITLE
JOURNAL
VOL.
PAGES
YEAR
ORGANISM (UNIPROT)
PUBMED ID
SOURCE
Tynes, R.E.; Sabourin, P.J.; Hodgson, E.
Identification of distinct hepatic and pulmonary forms of microsomal flavin-containing monooxygenase in the mouse and rabbit
Biochem. Biophys. Res. Commun.
126
1069-1075
1985
Oryctolagus cuniculus, Mus musculus
Tynes, R.E.; Hodgson, E.
Catalytic activity and substrate specificity of the flavin-containing monooxygenase in microsomal systems: characterization of the hepatic, pulmonary and renal enzymes of the mouse, rabbit, and rat
Arch. Biochem. Biophys.
240
77-93
1985
Oryctolagus cuniculus, Mus musculus, Rattus norvegicus, Sus scrofa
Chiba, K.; Kubota, E.; Miyakawa, T.; Kato, Y.; Ishizaki, T.
Characterization of hepatic microsomal metabolism as an in vivo detoxication pathway of 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine in mice
J. Pharmacol. Exp. Ther.
246
1108-1115
1988
Mus musculus, Mus musculus C-57 BL
Di Monte, D.A.; Wu, E.Y.; Irwin, I.; Delanney, L.E.; Langston, J.W.
Biotransformation of 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine in primary cultures of mouse astrocytes
J. Pharmacol. Exp. Ther.
258
594-600
1991
Mus musculus
Rasooly, R.; Kelley, D.S.; Greg, J.; Mackey, B.E.
Dietary trans 10, cis 12-conjugated linoleic acid reduces the expression of fatty acid oxidation and drug detoxification enzymes in mouse liver
Br. J. Nutr.
97
58-66
2007
Mus musculus
Krueger, S.K.; Vandyke, J.E.; Williams, D.E.; Hines, R.N.
The role of flavin-containing monooxygenase (FMO) in the metabolism of tamoxifen and other tertiary amines
Drug Metab. Rev.
38
139-147
2006
Homo sapiens, Mus musculus, Rattus norvegicus, Sus scrofa
Krueger, S.K.; Williams, D.E.
Mammalian flavin-containing monooxygenases: structure/function, genetic polymorphisms and role in drug metabolism
Pharmacol. Ther.
106
357-387
2005
Oryctolagus cuniculus, Homo sapiens, Mus musculus, Sus scrofa
Shephard, E.A.; Chandan, P.; Stevanovic-Walker, M.; Edwards, M.; Phillips, I.R.
Alternative promoters and repetitive DNA elements define the species-dependent tissue-specific expression of the FMO1 genes of human and mouse
Biochem. J.
406
491-499
2007
Mus musculus (P50285), Mus musculus, Homo sapiens (Q01740), Homo sapiens
Siddens, L.K.; Henderson, M.C.; Vandyke, J.E.; Williams, D.E.; Krueger, S.K.
Characterization of mouse flavin-containing monooxygenase transcript levels in lung and liver, and activity of expressed isoforms
Biochem. Pharmacol.
75
570-579
2008
Mus musculus
Zhang, J.; Cerny, M.A.; Lawson, M.; Mosadeghi, R.; Cashman, J.R.
Functional activity of the mouse flavin-containing monooxygenase forms 1, 3, and 5
J. Biochem. Mol. Toxicol.
21
206-215
2007
Mus musculus
Mitchell, S.
Flavin mono-oxygenase (FMO) - The other oxidase
Curr. Drug Metab.
9
280-284
2008
Oryctolagus cuniculus, Homo sapiens, Mus musculus, Rattus norvegicus, Sus scrofa
Zhang, J.; Chaluvadi, M.R.; Reddy, R.; Motika, M.S.; Richardson, T.A.; Cashman, J.R.; Morgan, E.T.
Hepatic flavin-containing monooxygenase gene regulation in different mouse inflammation models
Drug Metab. Dispos.
37
462-468
2009
Mus musculus
Novick, R.M.; Mitzey, A.M.; Brownfield, M.S.; Elfarra, A.A.
Differential localization of flavin-containing monooxygenase (FMO) isoforms 1, 3, and 4 in rat liver and kidney and evidence for expression of FMO4 in mouse, rat, and human liver and kidney microsomes
J. Pharmacol. Exp. Ther.
329
1148-1155
2009
Homo sapiens, Homo sapiens (P31512), Mus musculus, Rattus norvegicus (P36365), Rattus norvegicus (Q8K4B7), Rattus norvegicus (Q9EQ76)
Henderson, M.C.; Siddens, L.K.; Morre, J.T.; Krueger, S.K.; Williams, D.E.
Metabolism of the anti-tuberculosis drug ethionamide by mouse and human FMO1, FMO2 and FMO3 and mouse and human lung microsomes
Toxicol. Appl. Pharmacol.
233
420-427
2008
Homo sapiens, Homo sapiens (Q01740), Homo sapiens (Q99518), Mus musculus, Mus musculus (P50285), Mus musculus (Q8K2I3)
Novick, R.; Vezina, C.; Elfarra, A.
Isoform distinct time-, dose-, and castration-dependent alterations in flavin-containing monooxygenase expression in mouse liver after 2,3,7,8-tetrachlorodibenzo-p-dioxin treatment
Biochem. Pharmacol.
79
1345-1351
2010
Mus musculus (P50285), Mus musculus (P97501), Mus musculus (P97872), Mus musculus (Q8K2I3), Mus musculus (Q8VHG0), Mus musculus, Mus musculus C57/BL6J (P50285), Mus musculus C57/BL6J (P97501), Mus musculus C57/BL6J (P97872), Mus musculus C57/BL6J (Q8K2I3), Mus musculus C57/BL6J (Q8VHG0)
Celius, T.; Pansoy, A.; Matthews, J.; Okey, A.B.; Henderson, M.C.; Krueger, S.K.; Williams, D.E.
Flavin-containing monooxygenase-3: induction by 3-methylcholanthrene and complex regulation by xenobiotic chemicals in hepatoma cells and mouse liver
Toxicol. Appl. Pharmacol.
247
60-69
2010
Mus musculus (P97501), Mus musculus
Motika, M.S.; Zhang, J.; Ralph, E.C.; Dwyer, M.A.; Cashman, J.R.
pH dependence on functional activity of human and mouse flavin-containing monooxygenase 5
Biochem. Pharmacol.
83
962-968
2012
Homo sapiens (P49326), Homo sapiens, Mus musculus (P97872), Mus musculus
Tanino, T.; Bando, T.; Komada, A.; Nojiri, Y.; Okada, Y.; Ueda, Y.; Sakurai, E.
Hepatic flavin-containing monooxygenase 3 enzyme suppressed by type 1 allergy-produced nitric oxide
Drug Metab. Dispos.
45
1189-1196
2017
Mus musculus
Scott, F.; Gonzalez Malagon, S.G.; OBrien, B.A.; Fennema, D.; Veeravalli, S.; Coveney, C.R.; Phillips, I.R.; Shephard, E.A.
Identification of flavin-containing monooxygenase 5 (FMO5) as a regulator of glucose homeostasis and a potential sensor of gut bacteria
Drug Metab. Dispos.
45
982-989
2017
Mus musculus
Phillips, I.R.; Shephard, E.A.
Drug metabolism by flavin-containing monooxygenases of human and mouse
Expert. Opin. Drug Metab. Toxicol.
13
167-181
2017
Homo sapiens, Mus musculus
Liao, B.M.; McManus, S.A.; Hughes, W.E.; Schmitz-Peiffer, C.
Flavin-containing monooxygenase 3 reduces endoplasmic reticulum stress in lipid-treated hepatocytes
Mol. Endocrinol.
30
417-428
2016
Homo sapiens, Mus musculus
El-Serafi, I.; Terelius, Y.; Abedi-Valugerdi, M.; Naughton, S.; Saghafian, M.; Moshfegh, A.; Mattsson, J.; Potacova, Z.; Hassan, M.
Flavin-containing monooxygenase 3 (FMO3) role in busulphan metabolic pathway
PLoS ONE
12
e0187294
2017
Homo sapiens, Mus musculus
Chen, M.; Guan, B.; Xu, H.; Yu, F.; Zhang, T.; Wu, B.
The molecular mechanism regulating diurnal rhythm of flavin-containing monooxygenase 5 in mouse liver
Drug Metab. Dispos.
47
1333-1342
2019
Mus musculus (P97872), Mus musculus, Mus musculus C57BL/6 (P97872)
