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Literature summary for 1.14.13.8 extracted from

  • Tynes, R.E.; Hodgson, E.
    Catalytic activity and substrate specificity of the flavin-containing monooxygenase in microsomal systems: characterization of the hepatic, pulmonary and renal enzymes of the mouse, rabbit, and rat (1985), Arch. Biochem. Biophys., 240, 77-93.
    View publication on PubMed
Search for more literature for 1.14.13.8

Activating Compound

Activating Compound Comment Organism Structure
n-octylamine
-
 Sus scrofa
n-octylamine allosteric activation of pig liver and mouse lung enzymes, not mouse, rabbit or rat liver enzymes Mus musculus
n-octylamine allosteric activation of pig liver and mouse lung enzymes, not mouse, rabbit or rat liver enzymes Rattus norvegicus
n-octylamine allosteric activation of pig liver and mouse lung enzymes, not mouse, rabbit or rat liver enzymes Oryctolagus cuniculus

KM Value [mM]

KM Value [mM] KM Value Maximum [mM] Substrate Comment Organism Structure
additional information
-
 additional information
-
 Mus musculus
additional information
-
 additional information
-
 Rattus norvegicus
additional information
-
 additional information
-
 Sus scrofa
additional information
-
 additional information
-
 Oryctolagus cuniculus

Organism

Organism UniProt Comment Textmining
Mus musculus
-
-
-
Oryctolagus cuniculus
-
-
-
Rattus norvegicus
-
-
-
Sus scrofa
-
-
-

Source Tissue

Source Tissue Comment Organism Textmining
kidney
-
 Mus musculus
-
kidney
-
 Rattus norvegicus
-
kidney
-
 Oryctolagus cuniculus
-
liver
-
 Mus musculus
-
liver
-
 Rattus norvegicus
-
liver
-
 Sus scrofa
-
liver
-
 Oryctolagus cuniculus
-
lung
-
 Mus musculus
-
lung
-
 Rattus norvegicus
-
lung
-
 Oryctolagus cuniculus
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
1-butanethiol + NADPH + O2
-
 Mus musculus ?
-
 ?
1-butanethiol + NADPH + O2
-
 Rattus norvegicus ?
-
 ?
1-butanethiol + NADPH + O2
-
 Sus scrofa ?
-
 ?
1-butanethiol + NADPH + O2
-
 Oryctolagus cuniculus ?
-
 ?
2-mercaptobenzimidazole + NADPH + O2
-
 Mus musculus ?
-
 ?
2-mercaptobenzimidazole + NADPH + O2
-
 Rattus norvegicus ?
-
 ?
2-mercaptobenzimidazole + NADPH + O2
-
 Sus scrofa ?
-
 ?
2-mercaptobenzimidazole + NADPH + O2
-
 Oryctolagus cuniculus ?
-
 ?
alpha-naphthylthiourea + NADPH + O2
-
 Mus musculus ?
-
 ?
alpha-naphthylthiourea + NADPH + O2
-
 Rattus norvegicus ?
-
 ?
alpha-naphthylthiourea + NADPH + O2
-
 Sus scrofa ?
-
 ?
alpha-naphthylthiourea + NADPH + O2
-
 Oryctolagus cuniculus ?
-
 ?
aminopyrine + NADPH + O2
-
 Mus musculus ?
-
 ?
aminopyrine + NADPH + O2
-
 Rattus norvegicus ?
-
 ?
aminopyrine + NADPH + O2
-
 Sus scrofa ?
-
 ?
aminopyrine + NADPH + O2
-
 Oryctolagus cuniculus ?
-
 ?
cysteamine + NADPH + O2
-
 Mus musculus ?
-
 ?
cysteamine + NADPH + O2
-
 Rattus norvegicus ?
-
 ?
cysteamine + NADPH + O2
-
 Sus scrofa ?
-
 ?
cysteamine + NADPH + O2
-
 Oryctolagus cuniculus ?
-
 ?
dibenzylamine + NADPH + O2
-
 Mus musculus ?
-
 ?
dibenzylamine + NADPH + O2
-
 Rattus norvegicus ?
-
 ?
dibenzylamine + NADPH + O2
-
 Sus scrofa ?
-
 ?
dibenzylamine + NADPH + O2
-
 Oryctolagus cuniculus ?
-
 ?
ephedrine + NADPH + O2
-
 Mus musculus ?
-
 ?
ephedrine + NADPH + O2
-
 Rattus norvegicus ?
-
 ?
ephedrine + NADPH + O2
-
 Sus scrofa ?
-
 ?
ephedrine + NADPH + O2
-
 Oryctolagus cuniculus ?
-
 ?
ethylene sulfide + NADPH + O2
-
 Mus musculus ?
-
 ?
ethylene sulfide + NADPH + O2
-
 Rattus norvegicus ?
-
 ?
ethylene sulfide + NADPH + O2
-
 Sus scrofa ?
-
 ?
ethylene sulfide + NADPH + O2
-
 Oryctolagus cuniculus ?
-
 ?
imipramine + NADPH + O2
-
 Mus musculus ?
-
 ?
imipramine + NADPH + O2
-
 Rattus norvegicus ?
-
 ?
imipramine + NADPH + O2
-
 Sus scrofa ?
-
 ?
imipramine + NADPH + O2
-
 Oryctolagus cuniculus ?
-
 ?
methamphetamine + NADPH + O2
-
 Mus musculus ?
-
 ?
methamphetamine + NADPH + O2
-
 Rattus norvegicus ?
-
 ?
methamphetamine + NADPH + O2
-
 Sus scrofa ?
-
 ?
methamphetamine + NADPH + O2
-
 Oryctolagus cuniculus ?
-
 ?
methimazole + NADPH + O2
-
 Mus musculus N-methylmethimidazole-2-sulfinic acid + NADP+ + H2O
-
 ?
methimazole + NADPH + O2
-
 Rattus norvegicus N-methylmethimidazole-2-sulfinic acid + NADP+ + H2O
-
 ?
methimazole + NADPH + O2
-
 Sus scrofa N-methylmethimidazole-2-sulfinic acid + NADP+ + H2O
-
 ?
methimazole + NADPH + O2
-
 Oryctolagus cuniculus N-methylmethimidazole-2-sulfinic acid + NADP+ + H2O
-
 ?
methylphenylsulfide + NADPH + O2
-
 Mus musculus ?
-
 ?
methylphenylsulfide + NADPH + O2
-
 Rattus norvegicus ?
-
 ?
methylphenylsulfide + NADPH + O2
-
 Sus scrofa ?
-
 ?
methylphenylsulfide + NADPH + O2
-
 Oryctolagus cuniculus ?
-
 ?
additional information
-
 Sus scrofa ?
-
 ?
additional information overview on specificity Mus musculus ?
-
 ?
additional information overview on specificity Rattus norvegicus ?
-
 ?
additional information overview on specificity Oryctolagus cuniculus ?
-
 ?
N,N-dimethylaniline + NADPH + O2
-
 Mus musculus N,N-dimethylaniline N-oxide + NADP+ + H2O
-
 ?
N,N-dimethylaniline + NADPH + O2
-
 Rattus norvegicus N,N-dimethylaniline N-oxide + NADP+ + H2O
-
 ?
N,N-dimethylaniline + NADPH + O2
-
 Sus scrofa N,N-dimethylaniline N-oxide + NADP+ + H2O
-
 ?
N,N-dimethylaniline + NADPH + O2
-
 Oryctolagus cuniculus N,N-dimethylaniline N-oxide + NADP+ + H2O
-
 ?
N-aminopiperidine + NADPH + O2
-
 Mus musculus tetrazene + NADP+ + H2O + ?
-
 ?
N-aminopiperidine + NADPH + O2
-
 Rattus norvegicus tetrazene + NADP+ + H2O + ?
-
 ?
N-aminopiperidine + NADPH + O2
-
 Sus scrofa tetrazene + NADP+ + H2O + ?
-
 ?
p-chloro-N-methylaniline + NADPH + O2
-
 Mus musculus ?
-
 ?
p-chloro-N-methylaniline + NADPH + O2
-
 Rattus norvegicus ?
-
 ?
p-chloro-N-methylaniline + NADPH + O2
-
 Sus scrofa ?
-
 ?
p-chloro-N-methylaniline + NADPH + O2
-
 Oryctolagus cuniculus ?
-
 ?
phenylthiourea + NADPH + O2
-
 Mus musculus ?
-
 ?
phenylthiourea + NADPH + O2
-
 Rattus norvegicus ?
-
 ?
phenylthiourea + NADPH + O2
-
 Sus scrofa ?
-
 ?
phenylthiourea + NADPH + O2
-
 Oryctolagus cuniculus ?
-
 ?
thioacetamide + NADPH + O2
-
 Mus musculus ?
-
 ?
thioacetamide + NADPH + O2
-
 Rattus norvegicus ?
-
 ?
thioacetamide + NADPH + O2
-
 Sus scrofa ?
-
 ?
thioacetamide + NADPH + O2
-
 Oryctolagus cuniculus ?
-
 ?
thiobenzamide + NADPH + O2
-
 Mus musculus ?
-
 ?
thiobenzamide + NADPH + O2
-
 Rattus norvegicus ?
-
 ?
thiobenzamide + NADPH + O2
-
 Oryctolagus cuniculus ?
-
 ?
thiourea + NADPH + O2
-
 Mus musculus ?
-
 ?
thiourea + NADPH + O2
-
 Rattus norvegicus ?
-
 ?
thiourea + NADPH + O2
-
 Sus scrofa ?
-
 ?
thiourea + NADPH + O2
-
 Oryctolagus cuniculus ?
-
 ?
trimethylamine + NADPH + O2
-
 Mus musculus ?
-
 ?
trimethylamine + NADPH + O2
-
 Rattus norvegicus ?
-
 ?
trimethylamine + NADPH + O2
-
 Sus scrofa ?
-
 ?
trimethylamine + NADPH + O2
-
 Oryctolagus cuniculus ?
-
 ?

pH Optimum

pH Optimum Minimum pH Optimum Maximum Comment Organism
8.8
-
-
 Mus musculus
9
-
-
 Mus musculus
9.8
-
-
 Mus musculus
9.8
-
-
 Rattus norvegicus
9.8
-
-
 Oryctolagus cuniculus

pH Range

pH Minimum pH Maximum Comment Organism
additional information
-
-
 Mus musculus
additional information
-
-
 Rattus norvegicus
additional information
-
-
 Oryctolagus cuniculus

Cofactor

Cofactor Comment Organism Structure
FAD flavoprotein Mus musculus
FAD flavoprotein Rattus norvegicus
FAD flavoprotein Sus scrofa
FAD flavoprotein Oryctolagus cuniculus