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BRENDA support

Information on EC 1.1.1.88 - hydroxymethylglutaryl-CoA reductase

for references in articles please use BRENDA:EC1.1.1.88

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The expected taxonomic range for this enzyme is: Bacteria, Archaea, Eukaryota

Synonyms
hydroxymethylglutaryl-coa reductase, hydroxymethylglutaryl coenzyme a reductase, 3-hydroxy-3-methylglutaryl-coenzyme-a reductase, 3-hydroxy-3-methylglutaryl coa reductase 1, mt hmgr1, nadh-dependent hmg-coa reductase, more

REACTION
REACTION DIAGRAM
COMMENTARY hide
ORGANISM
UNIPROT
LITERATURE
(R)-mevalonate + CoA + 2 NAD+ = 3-hydroxy-3-methylglutaryl-CoA + 2 NADH + 2 H+
show the reaction diagram