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Protein Variants:
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EC Number
Protein Variants
Commentary
Reference
1.1.1.88
C156/296 A
fully active, resistant to N-ethylmaleimide
287500
1.1.1.88
C156A
fully active, resistant to N-ethylmaleimide
287500
1.1.1.88
C296A
fully active
287500
1.1.1.88
D146A
6670-fold more specific for NADP+ than wild-type
287505
1.1.1.88
D146A/L148K
72200-fold more specific for NADP+ than wild-type
287505
1.1.1.88
D146A/L148R
83300-fold more specific for NADP+ than wild-type
287505
1.1.1.88
D146A/Q147K
no activity with NADP+ as cofactor
287505
1.1.1.88
D146A/T192K
no activity with NADP+ as cofactor
287505
1.1.1.88
D146A/T192R
no activity with NADP+ as cofactor
287505
1.1.1.88
D146G
1170-fold more specific for NADP+ than wild-type
287505
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