2.4.1.34: 1,3-beta-glucan synthase

This is an abbreviated version!
For detailed information about 1,3-beta-glucan synthase, go to the full flat file.

Word Map on EC 2.4.1.34

2.4.1.34

candida

echinocandins

albicans

caspofungin

cytokinesis

micafungin

amphotericin

candidiasis

rho1

anidulafungin

powdery

plasmodesmata

mildew

pneumocandins

microspore

papulacandins

calcofluor

symplastic

candidemia

aculeacin

echinocandin-resistant

agriculture

analysis

medicine

Reaction

Synonyms

(1,3)-beta-D-glucan (curdlan) synthase, (1,3)-beta-D-glucan synthase, (1,3)-beta-glucan (callose) synthase, (1,3)beta-D-glucan synthase, 1,3-beta-D-glucan 3-beta-D-glucosyltransferase, 1,3-beta-D-glucan synthase, 1,3-beta-D-glucan synthetase, 1,3-beta-D-glucan-UDP glucosyltransferase, 1,3-beta-glucan synthase, 1,3-beta-glucan synthase (GS), 1,3-beta-glucan-uridine diphosphoglucosyltransferase, Arabidopsis beta-1,3-glucan synthase, beta(1,3)-D-glucan synthase, beta(1,3)glucan synthase, beta-1,3-glucan synthase, beta-1,3-glucan synthetase, beta-glucan synthase, Bgs1p, bgs2p, Bgs3p, Bgs4p, callose synthase, callose synthetase, CalS, CrdS, curdlan synthase, Fks, FKS-1, Fks1p, FKS2, GCS1, GLS1, glucan synthase (GS), glucan synthase-like, glucan synthase-like 1, GS-II, Gsc-1, Gsc1, GSC2, GSL, GSL1, GSL8, MaFKS, More, paramylon synthetase, PbFKS1, PMR, PNEG_03180, PNEJI1_001061, UDP-glucose-1,3-beta-glucan glucosyltransferase, UDP-glucose-beta-glucan glucosyltransferase, UDP-glucose:(1,3)beta-glucan synthase, UDPglucose-1,3-beta-D-glucan glucosyltransferase, uridine diphosphoglucose-1,3-beta-glucan glucosyltransferase, uridine-diphosphate glucose:1,3-beta-D-glucosyltransferase, ZT1E4_G10604

ECTree

2 Transferases

2.4 Glycosyltransferases

2.4.1 Hexosyltransferases

2.4.1.34 1,3-beta-glucan synthase

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Results	in table
72	Activating Compound
5641	AA Sequence
6	Application
1	CAS Registry Number
14	Cloned(Commentary)
2	Cofactor
1	Crystallization (Commentary)
4	Expression
16	General Information
10	General Stability
3	IC50 Value
155	Inhibitors
5	Ki Value [mM]
26	KM Value [mM]
37	Localization
29	Metals/Ions
20	Molecular Weight [Da]
47	Natural Substrates/ Products (Substrates)
152	Organism
3	Pathway
16	pH Optimum
7	pH Range
37	Protein Variants
12	Purification (Commentary)
3	Reaction
2	Reaction Type
125	Reference
38	Source Tissue
22	Specific Activity [micromol/min/mg]
14	Storage Stability
82	Substrates and Products (Substrate)
22	Subunits
121	Synonyms
1	Systematic Name
9	Temperature Optimum [°C]
2	Temperature Range [°C]
11	Temperature Stability [°C]
4	Turnover Number [1/s]

Activating Compound

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Activating Compound on EC 2.4.1.34 - 1,3-beta-glucan synthase

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3-[(cholamidopropyl)dimethyl(ammonio)]propanesulfonate

Arachis hypogaea

stimulate

489062

Acylcarnitine

Glycine max

inhibition in presence of digitonin, stimulation in absence of digitonin within a certain concentration range

489068

alamethicin

2 entries

beta-furfuryl-beta-D-glucoside

Spinacia oleracea

stimulation

489069

beta-linked glucosides

Gossypium hirsutum

stimulate

489056

beta-methyl-D-glucoside

Beta vulgaris

stimulate

489059

bovine serum albumin

7 entries

CaCl2

Cryptococcus neoformans

7 mM, 2fold increase in activity

cellobiose

cellobiosylglucose

stimulate

CHAPS

pollen CalS isozyme is activated in vitro by the detergent CHAPS, but activation is not associated with a detectable change in the molecular mass of the NaGSL1 polypeptide

cytochalasin

slightly activating

D-glucose

D-glucosides

Digitonin

stimulate

Echinocandin B

inhibition in presence of digitonin, stimulation in absence of digitonin within a certain concentration range

489068

EDTA

Cryptococcus neoformans

maximal activity at 50 mM

657562

gentiobiose

2 entries

glycerol

Saccharomyces cerevisiae

stimulate

489057

GTP

9 entries

hydroquinone-beta-D-glucoside

Beta vulgaris

stimulate

489059

laminaribiose

4 entries

lysophosphatidylcholine

Glycine max

inhibition in presence of digitonin, stimulation in absence of digitonin within a certain concentration range

489068

maltose

2 entries

MgCl2

Cryptococcus neoformans

5 mM, 3fold increase in activity

657562

platelet-activating factor

Glycine max

inhibition in presence of digitonin, stimulation in absence of digitonin within a certain concentration range

polyamines

stimulate

Polyols

Salicin

stimulate

spermine

sucrose

stimulate

Trypsin

pollen CalS isozyme, in contrast to the somatic isozyme, is activated in vitro by the proteolytic enzyme trypsin, but activation is not associated with a detectable change in the molecular mass of the NaGSL1 polypeptide. Some CalS activity is lost with longer incubations with trypsin

702118

additional information

7 entries