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1.14.14.166: (S)-N-methylcanadine 1-hydroxylase

This is an abbreviated version!
For detailed information about (S)-N-methylcanadine 1-hydroxylase, go to the full flat file.

Reaction

(S)-N-methylcanadine
+
[reduced NADPH-hemoprotein reductase]
+
O2
=
(S)-1-hydroxy-N-methylcanadine
+
[oxidized NADPH-hemoprotein reductase]
+
H2O

Synonyms

1-hydroxy-N-methylcanadine synthase, CYP82Y1, N-methylcanadine 1-hydroxylase, PbCYP82Y1

ECTree

     1 Oxidoreductases
         1.14 Acting on paired donors, with incorporation or reduction of molecular oxygen
             1.14.14 With reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen into the other donor
                1.14.14.166 (S)-N-methylcanadine 1-hydroxylase

Reference

Reference on EC 1.14.14.166 - (S)-N-methylcanadine 1-hydroxylase

Please use the Reference Search for a specific query.
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REF.
AUTHORS
TITLE
JOURNAL
VOL.
PAGES
YEAR
ORGANISM (UNIPROT)
PUBMED ID
SOURCE
Li, Y.; Li, S.; Thodey, K.; Trenchard, I.; Cravens, A.; Smolke, C.
Complete biosynthesis of noscapine and halogenated alkaloids in yeast
Proc. Natl. Acad. Sci. USA
115
E3922-E3931
2018
Papaver somniferum (I3PLR1)
Manually annotated by BRENDA team
Dang, T.T.; Facchini, P.J.
CYP82Y1 is N-methylcanadine 1-hydroxylase, a key noscapine biosynthetic enzyme in opium poppy
J. Biol. Chem.
289
2013-2026
2014
Papaver somniferum (I3PLR1), Papaver somniferum
Manually annotated by BRENDA team
Abedini, D.; Monfared, S.R.; Abbasi, A.
The effects of promoter variations of the N-methylcanadine 1-hydroxylase (CYP82Y1) gene on the noscapine production in opium poppy
Sci. Rep.
8
4973
2018
Papaver bracteatum, Papaver somniferum (I3PLR1), Papaver somniferum
Manually annotated by BRENDA team