Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|
(S)-N-methylcanadine + [reduced NADPH-hemoprotein reductase] + O2 | Papaver bracteatum | the enzyme participates in the biosynthesis of the isoquinoline alkaloid noscapine | (S)-1-hydroxy-N-methylcanadine + [oxidized NADPH-hemoprotein reductase] + H2O | - |
? | |
(S)-N-methylcanadine + [reduced NADPH-hemoprotein reductase] + O2 | Papaver somniferum | the enzyme participates in the biosynthesis of the isoquinoline alkaloid noscapine | (S)-1-hydroxy-N-methylcanadine + [oxidized NADPH-hemoprotein reductase] + H2O | - |
? |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Papaver bracteatum | - |
- |
- |
Papaver somniferum | I3PLR1 | - |
- |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
leaf | - |
Papaver somniferum | - |
leaf | expression is lower than in Papaver somniferum | Papaver bracteatum | - |
seed | - |
Papaver somniferum | - |
stem | - |
Papaver somniferum | - |
stem | expression is lower than in Papaver somniferum | Papaver bracteatum | - |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
(S)-N-methylcanadine + [reduced NADPH-hemoprotein reductase] + O2 | - |
Papaver bracteatum | (S)-1-hydroxy-N-methylcanadine + [oxidized NADPH-hemoprotein reductase] + H2O | - |
? | |
(S)-N-methylcanadine + [reduced NADPH-hemoprotein reductase] + O2 | - |
Papaver somniferum | (S)-1-hydroxy-N-methylcanadine + [oxidized NADPH-hemoprotein reductase] + H2O | - |
? | |
(S)-N-methylcanadine + [reduced NADPH-hemoprotein reductase] + O2 | the enzyme participates in the biosynthesis of the isoquinoline alkaloid noscapine | Papaver bracteatum | (S)-1-hydroxy-N-methylcanadine + [oxidized NADPH-hemoprotein reductase] + H2O | - |
? | |
(S)-N-methylcanadine + [reduced NADPH-hemoprotein reductase] + O2 | the enzyme participates in the biosynthesis of the isoquinoline alkaloid noscapine | Papaver somniferum | (S)-1-hydroxy-N-methylcanadine + [oxidized NADPH-hemoprotein reductase] + H2O | - |
? |
Synonyms | Comment | Organism |
---|---|---|
CYP82Y1 | - |
Papaver somniferum |
N-methylcanadine 1-hydroxylase | - |
Papaver bracteatum |
N-methylcanadine 1-hydroxylase | - |
Papaver somniferum |
PbCYP82Y1 | - |
Papaver bracteatum |
Organism | Comment | Expression |
---|---|---|
Papaver somniferum | an SSR (Simple Sequence Repeats) is embedded in the promoter region of the CYP82Y1 gene. Quantitative PCR shows that a variation in the motif repeat number (either a decrease or increase) down-regulates the expression of the CYP82Y1 gene | down |
General Information | Comment | Organism |
---|---|---|
metabolism | the enzyme participates in the biosynthesis of the isoquinoline alkaloid noscapine | Papaver bracteatum |
metabolism | the enzyme participates in the biosynthesis of the isoquinoline alkaloid noscapine | Papaver somniferum |