1.14.14.166: (S)-N-methylcanadine 1-hydroxylase

This is an abbreviated version!
For detailed information about (S)-N-methylcanadine 1-hydroxylase, go to the full flat file.

Reaction

Synonyms

1-hydroxy-N-methylcanadine synthase, CYP82Y1, N-methylcanadine 1-hydroxylase, PbCYP82Y1

ECTree

1 Oxidoreductases

1.14 Acting on paired donors, with incorporation or reduction of molecular oxygen

1.14.14 With reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen into the other donor

1.14.14.166 (S)-N-methylcanadine 1-hydroxylase

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Results	in table
1	AA Sequence
1	Cloned(Commentary)
2	Cofactor
1	Expression
5	General Information
4	Natural Substrates/ Products (Substrates)
4	Organism
4	Pathway
1	Reaction
4	Reference
9	Source Tissue
8	Substrates and Products (Substrate)
9	Synonyms
1	Systematic Name

General Information

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General Information on EC 1.14.14.166 - (S)-N-methylcanadine 1-hydroxylase

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malfunction

Papaver somniferum

I3PLR1

suppression of CYP82Y1 using virus-induced gene silencing causes a significant reduction in the levels of noscapine, narcotoline, and a putative downstream secoberbine intermediate and also results in increased accumulation of the upstream pathway intermediates scoulerine, tetrahydrocolumbamine, canadine, and N-methylcanadine

751038

metabolism

4 entries