Reference on EC 6.2.1.1 - acetate-CoA ligase
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REF. 
AUTHORS
TITLE
JOURNAL
VOL.
PAGES
YEAR
ORGANISM (UNIPROT)
PUBMED ID
SOURCE
Patel, S.S.; Walt, D.R.
Substrate specificity of acetyl coenzyme A synthetase
J. Biol. Chem.
262
7132-7134
1987
Saccharomyces cerevisiae
Connerton, I.F.; Fincham, J.R.; Sandeman, R.A.; Hynes, U.K.
Comparison and cross-species expression of the acetyl-CoA synthetase genes of the Ascomycete fungi, Aspergillus nidulans and Neurospora crassa
Mol. Microbiol.
4
451-460
1990
Aspergillus nidulans, Neurospora crassa
Kohler, H.P.; Zehnder, A.J.B.
Carbon monoxide dehydrogenase and acetate thiokinase in Methanothrix soehngenii
FEMS Microbiol. Lett.
21
287-292
1984
Methanothrix soehngenii
-
Maruyama, K.
Short-chain acyl-coenzyme A synthetase in Rhodopseudomonas sphaeroides
J. Biochem.
91
725-730
1982
Cereibacter sphaeroides
Frenkel, E.P.; Kitchens, R.L.
Acetyl-CoA synthetase from baker¦s yeast (Saccharomyces cerevisiae)
Methods Enzymol.
71
317-324
1981
Saccharomyces cerevisiae
Oberlies, G.; Fuchs, G.; Thauer, R.K.
Acetate thiokinase and the assimilation of acetate in Methanobacterium thermoautotrophicum
Arch. Microbiol.
128
248-252
1980
Methanothermobacter thermautotrophicus
Satyanarayana, T.; Chervenka, C.H.; Klein, H.P.
Subunit specificity of the two acetyl-CoA synthetases of yeast as revealed by an immunological approach
Biochim. Biophys. Acta
614
601-606
1980
Saccharomyces cerevisiae, Saccharomyces cerevisiae LK2G12
Scaife, J.R.; Tichivangana, J.Z.
Short chain acyl-CoA synthetase in ovine rumen epithelium
Biochim. Biophys. Acta
619
445-450
1980
Ovis aries
Woodnutt, G.; Parker, D.S.
Rabbit liver acetyl-CoA synthetase
Biochem. J.
175
757-759
1978
Oryctolagus cuniculus
Frenkel, E.P.; Kitchens, R.L.
Purification and properties of acetyl coenzyme A synthetase from baker¦s yeast
J. Biol. Chem.
252
504-507
1977
Saccharomyces cerevisiae
O'Sullivan, J.; Ettlinger, L.
Characterization of the acetyl-CoA synthetase of Acetobacter aceti
Biochim. Biophys. Acta
450
410-417
1976
Acetobacter aceti
Satyanarayana, T.; Klein, H.P.
Studies on the aerobic acetyl-coenzyme A synthetase of Saccharomyces cerevisiae: purification, crystallization, and physical properties of the enzyme
Arch. Biochem. Biophys.
174
480-490
1976
Saccharomyces cerevisiae, Saccharomyces cerevisiae LK2G12
Reijnierse, G.L.A.; Veldstra, H.; Van den Berg, C.J.
Short-chain fatty acid synthesis in brain. Subcellular localization and changes during development
Biochem. J.
152
477-484
1975
Rattus norvegicus
Londesborough, J.C.; Webster, L.T.
Fatty acyl-CoA synthetases
The Enzymes, 3rd Ed. (Boyer, P. D. , ed. )
10
469-488
1974
Aspergillus niger, Bos taurus, Euglena gracilis, Oryctolagus cuniculus, Rattus norvegicus
-
Satyanarayana, T.; Mandel, A.D.; Klein, H.P.
Evidence for two immunologically distinct acetyl-coenzyme A synthetases in yeast
Biochim. Biophys. Acta
341
396-401
1974
Saccharomyces cerevisiae, Saccharomyces cerevisiae LK2G12
Young, O.A.; Anderson, J.W.
The enzymology of short-chain fatty acyl-coenzyme A synthetase from seed of Pinus radiata
Biochem. J.
137
435-442
1974
Pinus radiata
Satyanarayana, T.; Klein, H.P.
Studies on acetyl-coenzyme A synthetase of yeast: inhibition by long-chain acyl-coenzyme A esters
J. Bacteriol.
115
600-606
1973
Saccharomyces cerevisiae, Saccharomyces cerevisiae LK2G12
Londesborough, J.L.; Yuan, S.L.; Webster, L.T.
The molecular weight and thiol residues of acetyl-coenzyme A synthetase from ox heart mitochondria
Biochem. J.
133
23-36
1973
Bos taurus
Preston, G.G.; Wall, J.D.; Emerich, D.W.
Purification and properties of acetyl-CoA synthetase from Bradyrhizobium japonicum bacteroids
Biochem. J.
267
179-183
1990
Bradyrhizobium japonicum
Jetten, M.S.M.; Stams, A.J.M.; Zehnder, A.J.B.
Isolation and characterization of acetyl-coenzyme A synthetase from Methanothrix soehngenii
J. Bacteriol.
171
5430-5435
1989
Methanothrix soehngenii
Focke, M.; Feld, A.; Lichtenthaler, H.K.
Allicin, a naturally occuring antibiotic from garlic, specifically inhibits acetyl-CoA synthetase
FEBS Lett.
261
106-108
1990
Bos taurus, Saccharomyces cerevisiae, Hordeum vulgare
Khramtsov, N.V.; Blunt, D.S.; Montelone, B.A.; Upton, S.J.
The putative acetyl-CoA synthetase gene of Cryptosporidium parvum and a new conserved protein motif in acetyl-CoA synthetases
J. Parasitol.
82
423-427
1996
Cryptosporidium parvum
Ishikawa, M.; Fujino, T.; Sakashita, H.; Morikawa, K.; Yamamoto, T.
Kinetic properties and structural characterization of highly purified acetyl-CoA synthetase from bovine heart and tissue distribution of the enzyme in rat tissues
Tohoku J. Exp. Med.
175
55-57
1995
Bos taurus, Rattus norvegicus
Van den Berg, M.A.; de Jong-Gubbels, P.; Kortland, C.J.; van Dijken, J.P.; Pronk, J.T.; Steensma, H.Y.
The two acetyl-coenzyme A synthetases of Saccharomyces cerevisiae differ with respect to kinetic properties and transcriptional regulation
J. Biol. Chem.
271
28953-28959
1996
Saccharomyces cerevisiae
Martinez-Blanco, H.; Reglero, A.; Fenandez-Valverde, M.; Ferrero, M.A.; Moreno, M.A.; Penalva, M.A.; Luengo, J.M.
Isolation and characterization of the acetyl-CoA synthetase from Penicillium chrysogenum
J. Biol. Chem.
267
5474-5481
1992
Aspergillus nidulans, Penicillium chrysogenum
Knudsen, C.T.; Immerdal, L.; Grunnet, N.; Quistorff, B.
Periportal zonation of the cytosolic acetyl-CoA synthetase of male rat liver
Eur. J. Biochem.
204
359-362
1992
Rattus norvegicus
Roughan, P.G.; Ohlrogge, J.B.
On the assay of acetyl-CoA synthetase activity in chloroplasts and leaf extracts
Anal. Biochem.
216
77-82
1994
Amaranthus sp., Pisum sativum, Spinacia oleracea, Zea mays
Guranowski, A.; Gunther Sillero, M.A.; Sillero, A.
Adenosine 5'-tetraphosphate and adenosine 5'-pentaphosphate are synthesized by yeast acetyl coenzyme A synthetase
J. Bacteriol.
176
2986-2990
1994
Saccharomyces cerevisiae
Kumari, S.; Tishel, R.; Eisenbach, M.; Wolfe, A.J.
Cloning, characterization, and functional expression of acs, the gene which encodes acetyl coenzyme A synthetase in Escherichia coli
J. Bacteriol.
177
2878-2886
1995
Escherichia coli
Garre, V.; Murillo, F.J.; Torres-Martinez, S.
Isolation of the facA (acetyl-CoA synthetase) gene of Phycomyces blakesleeanus
Mol. Gen. Genet.
244
278-286
1994
Phycomyces blakesleeanus
Khoo, H.G.; Wong, K.P.
Acetyl CoA generation and N-acetylation of serotonin (5HT) in the mosquito, Aedes togoi
Insect Biochem. Mol. Biol.
24
445-451
1994
Aedes togoi
Biriukov, A.I.; Zhukov, I.; Zhukov, N.; Kopelevich, V.M.; Bulanova, L.N.; Gunar, V.I.
Analogs of 3¦-dephospho-CoASH with a phosphodiester bond as substrates of the S-acetylation reaction, catalyzed by acetyl-CoA-synthetase from rabbit myocardium
Bioorg. Khim.
19
905-911
1993
Oryctolagus cuniculus
Klein, H.P.; Jahnke, L.
Effects of aeration on formation and localization of the acetyl coenzyme A synthetases of Saccharomyces cerevisiae
J. Bacteriol.
137
179-184
1979
Saccharomyces cerevisiae
Eggen, R.I.L.; Geerling, A.C.M.; Boshoven, A.B.P.; de Vos, W.M.
Cloning, sequence analysis and functional expression of the acetyl coenzyme A synthetase gene from Methanothrix soehngenii in Escherichia coli
J. Bacteriol.
173
6383-6389
1991
Methanothrix soehngenii
Sone, H.; Shimano, H.; Sakakura, Y.; Inoue, N.; Amemiya-Kudo, M.; Yahagi, N.; Osawa, M.; Suzuki, H.; Yokoo, T.; Takahashi, A.; Iida, K.; Toyoshima, H.; Iwama, A.; Yamada, N.
Acetyl-coenzyme A synthetase is a lipogenic enzyme controlled by SREBP-1 and energy status
Am. J. Physiol.
282
E222-E230
2002
Mus musculus
Behal, R.H.; Lin, M.; Back, S.; Oliver, D.J.
Role of acetyl-coenzyme A synthetase in leaves of Arabidopsis thaliana
Arch. Biochem. Biophys.
402
259-267
2002
Arabidopsis thaliana, Pisum sativum
Starai, V.J.; Takahashi, H.; Boeke, J.D.; Escalante-Semerena, J.C.
Short-chain fatty acid activation by acyl-coenzyme A synthetases requires SIR2 protein function in Salmonella enterica and Saccharomyces cerevisiae
Genetics
163
545-555
2003
Saccharomyces cerevisiae
Kumari, S.; Beatty, C.M.; Browning, D.F.; Busby, S.J.W.; Simel, E.J.; Hovel-Miner, G.; Wolfe, A.J.
Regulation of acetyl coenzyme A synthetase in Escherichia coli
J. Bacteriol.
182
4173-4179
2000
Escherichia coli
Luong, A.; Hannah, V.C.; Brown, M.S.; Goldstein, J.L.
Molecular characterization of human acetyl-CoA synthetase, an enzyme regulated by sterol regulatory element-binding proteins
J. Biol. Chem.
275
26458-26466
2000
Homo sapiens (Q9NR19), Homo sapiens
Fujino, T.; Kondo, J.; Ishikawa, M.; Morikawa, K.; Yamamoto, T.T.
Acetyl-CoA synthetase 2, a mitochondrial matrix enzyme involved in the oxidation of acetate
J. Biol. Chem.
276
11420-11426
2001
Mus musculus, Mus musculus (Q99NB1), Bos taurus (Q9BEA3), Bos taurus
Starai, V.J.; Celic, I.; Cole, R.N.; Boeke, J.D.; Escalante-Semerena, J.C.
Sir2-dependent activation of acetyl-CoA synthetase by deacetylation of active lysine
Science
298
2390-2392
2002
Salmonella enterica
Hegg, E.L.
Unraveling the structure and mechanism of acetyl-coenzyme A synthase
Acc. Chem. Res.
37
775-783
2004
Moorella thermoacetica
Jogl, G.; Tong, L.
Crystal structure of yeast acetyl-coenzyme A synthetase in complex with AMP
Biochemistry
43
1425-1431
2004
Saccharomyces cerevisiae (Q01574), Saccharomyces cerevisiae
Bräsen, C.; Schonheit, P.
AMP-forming acetyl-CoA synthetase from the extremely halophilic archaeon Haloarcula marismortui: purification, identification and expression of the encoding gene, and phylogenetic affiliation
Extremophiles
9
355-365
2005
Haloarcula marismortui
Brasen, C.; Urbanke, C.; Schonheit, P.
A novel octameric AMP-forming acetyl-CoA synthetase from the hyperthermophilic crenarchaeon Pyrobaculum aerophilum
FEBS Lett.
579
477-482
2005
Pyrobaculum aerophilum
Webster, C.E.; Darensbourg, M.Y.; Lindahl, P.A.; Hall, M.B.
Structures and energetics of models for the active site of acetyl-coenzyme A synthase: role of distal and proximal metals in catalysis
J. Am. Chem. Soc.
126
3410-3411
2004
Moorella thermoacetica
Starai, V.J.; Gardner, J.G.; Escalante-Semerena, J.C.
Residue Leu-641 of acetyl-CoA synthetase is critical for the acetylation of residue Lys-609 by the protein acetyltransferase enzyme of Salmonella enterica
J. Biol. Chem.
280
26200-26205
2005
Salmonella enterica
Lin, H.; Castro, N.M.; Bennett, G.N.; San, K.Y.
Acetyl-CoA synthetase overexpression in Escherichia coli demonstrates more efficient acetate assimilation and lower acetate accumulation: a potential tool in metabolic engineering
Appl. Microbiol. Biotechnol.
71
870-874
2006
Escherichia coli
Ingram-Smith, C.; Smith, K.S.
AMP-forming acetyl-CoA synthetases in Archaea show unexpected diversity in substrate utilization
Archaea
2
95-107
2007
Archaeoglobus fulgidus, Methanothermobacter thermautotrophicus (Q2XNL6), Methanothermobacter thermautotrophicus
Ingram-Smith, C.; Woods, B.I.; Smith, K.S.
Characterization of the acyl substrate binding pocket of acetyl-CoA synthetase
Biochemistry
45
11482-11490
2006
Methanothermobacter thermautotrophicus, Methanothermobacter thermautotrophicus Z245
Bramlett, M.R.; Stubna, A.; Tan, X.; Surovtsev, I.V.; Muenck, E.; Lindahl, P.A.
Moessbauer and EPR study of recombinant acetyl-CoA synthase from Moorella thermoacetica
Biochemistry
45
8674-8685
2006
Moorella thermoacetica
Reger, A.S.; Carney, J.M.; Gulick, A.M.
Biochemical and crystallographic analysis of substrate binding and conformational changes in acetyl-CoA synthetase
Biochemistry
46
6536-6546
2007
Salmonella enterica
Loncaric, C.; Ward, A.F.; Walker, K.D.
Expression of an acetyl-CoA synthase and a CoA-transferase in Escherichia coli to produce modified taxanes in vivo
Biotechnol. J.
2
266-274
2007
Taxus sp.
Arias-Barrau, E.; Olivera, E.R.; Sandoval, A.; Naharro, G.; Luengo, J.M.
Acetyl-CoA synthetase from Pseudomonas putida U is the only acyl-CoA activating enzyme induced by acetate in this bacterium
FEMS Microbiol. Lett.
260
36-46
2006
Pseudomonas putida (Q6EMJ3), Pseudomonas putida
Baldock, M.I.; Denger, K.; Smits, T.H.; Cook, A.M.
Roseovarius sp. strain 217: aerobic taurine dissimilation via acetate kinase and acetate-CoA ligase
FEMS Microbiol. Lett.
271
202-206
2007
Roseovarius sp., Roseovarius sp. 217
Kuang, Y.; Salem, N.; Wang, F.; Schomisch, S.J.; Chandramouli, V.; Lee, Z.
A colorimetric assay method to measure acetyl-CoA synthetase activity: application to woodchuck model of hepatitis virus-induced hepatocellular carcinoma
J. Biochem. Biophys. Methods
70
649-655
2007
Marmota monax
Takahashi, H.; McCaffery, J.M.; Irizarry, R.A.; Boeke, J.D.
Nucleocytosolic acetyl-coenzyme a synthetase is required for histone acetylation and global transcription
Mol. Cell
23
207-217
2006
Saccharomyces cerevisiae
Schwer, B.; Bunkenborg, J.; Verdin, R.O.; Andersen, J.S.; Verdin, E.
Reversible lysine acetylation controls the activity of the mitochondrial enzyme acetyl-CoA synthetase 2
Proc. Natl. Acad. Sci. USA
103
10224-10229
2006
Homo sapiens (Q9NUB1), Homo sapiens
Hallows, W.C.; Lee, S.; Denu, J.M.
Sirtuins deacetylate and activate mammalian acetyl-CoA synthetases
Proc. Natl. Acad. Sci. USA
103
10230-10235
2006
Mus musculus
Doukov, T.I.; Blasiak, L.C.; Seravalli, J.; Ragsdale, S.W.; Drennan, C.L.
Xenon in and at the end of the tunnel of bifunctional carbon monoxide dehydrogenase/acetyl-CoA synthase
Biochemistry
47
3474-3483
2008
Moorella thermoacetica
Tan, X.; Lindahl, P.A.
Tunnel mutagenesis and Ni-dependent reduction and methylation of the alpha subunit of acetyl coenzyme A synthase/carbon monoxide dehydrogenase
J. Biol. Inorg. Chem.
13
771-778
2008
Moorella thermoacetica
Tan, X.; Martinho, M.; Stubna, A.; Lindahl, P.A.; Munck, E.
Moessbauer evidence for an exchange-coupled {[Fe4S4]1+ Nip1+} a-cluster in isolated alpha subunits of acetyl-coenzyme A synthase/carbon monoxide dehydrogenase
J. Am. Chem. Soc.
130
6712-6713
2008
Moorella thermoacetica
Gardner, J.G.; Escalante-Semerena, J.C.
Biochemical and mutational analyses of AcuA, the acetyltransferase enzyme that controls the activity of the acetyl coenzyme A synthetase (AcsA) in Bacillus subtilis
J. Bacteriol.
190
5132-5136
2008
Bacillus subtilis
Studer, S.V.; Mandel, M.J.; Ruby, E.G.
AinS quorum sensing regulates the Vibrio fischeri acetate switch
J. Bacteriol.
190
5915-5923
2008
Aliivibrio fischeri
Abe, T.; Hashimoto, Y.; Hosaka, H.; Tomita-Yokotani, K.; Kobayashi, M.
Discovery of amide (peptide) bond synthetic activity in acyl-CoA synthetase
J. Biol. Chem.
283
11312-11321
2008
Saccharomyces cerevisiae
Braesen, C.; Schmidt, M.; Groetzinger, J.; Schoenheit, P.
Reaction mechanism and structural model of ADP-forming acetyl-CoA synthetase from the hyperthermophilic archaeon Pyrococcus furiosus: evidence for a second active site histidine residue
J. Biol. Chem.
283
15409-15418
2008
Pyrococcus furiosus
Yan, J.; Barak, R.; Liarzi, O.; Shainskaya, A.; Eisenbach, M.
In vivo acetylation of CheY, a response regulator in chemotaxis of Escherichia coli
J. Mol. Biol.
376
1260-1271
2008
Escherichia coli
Lin, M.; Oliver, D.J.
The role of acetyl-coenzyme A synthetase in Arabidopsis
Plant Physiol.
147
1822-1829
2008
Arabidopsis thaliana (B9DGD6)
Yoshii, Y.; Furukawa, T.; Yoshii, H.; Mori, T.; Kiyono, Y.; Waki, A.; Kobayashi, M.; Tsujikawa, T.; Kudo, T.; Okazawa, H.; Yonekura, Y.; Fujibayashi, Y.
Cytosolic acetyl-CoA synthetase affected tumor cell survival under hypoxia: the possible function in tumor acetyl-CoA/acetate metabolism
Cancer Sci.
100
821-827
2009
Mus musculus
Matsumoto, T.; Ito, M.; Kotera, M.; Tatsumi, K.
A dinuclear nickel complex modeling of the Ni(d)(II)-Ni(p)(I) state of the active site of acetyl CoA synthase
Dalton Trans.
39
2995-2997
2010
synthetic construct
Anderson, K.; Apolinario, E.; MacAuley, S.; Sowers, K.
A 5' leader sequence regulates expression of methanosarcinal CO dehydrogenase/acetyl coenzyme A synthase
J. Bacteriol.
191
7123-7128
2009
Methanosarcina sp.
Yun, M.; Bang, S.H.; Kim, J.W.; Park, J.Y.; Kim, K.S.; Lee, J.D.
The importance of acetyl coenzyme A synthetase for 11C-acetate uptake and cell survival in hepatocellular carcinoma
J. Nucl. Med.
50
1222-1228
2009
Homo sapiens
Falcon, A.A.; Chen, S.; Wood, M.S.; Aris, J.P.
Acetyl-coenzyme A synthetase 2 is a nuclear protein required for replicative longevity in Saccharomyces cerevisiae
Mol. Cell. Biochem.
333
99-108
2010
Saccharomyces cerevisiae
Bender, G.; Ragsdale, S.
Evidence that ferredoxin interfaces with an internal redox shuttle in acetyl-CoA synthase during reductive activation and catalysis
Biochemistry
50
276-286
2011
Moorella thermoacetica
Liu, Y.; Zhu, X.; Wang, F.; Ying, T.; Li, P.; Huang, Z.; Tan, X.
Probing the role of the bridging C509 between the [Fe4S 4] cubane and the [NipNid] centre in the A-cluster of acetyl-coenzyme A synthase
Chem. Commun. (Camb. )
47
1291-1293
2011
Moorella thermoacetica
Chan, C.; Garrity, J.; Crosby, H.; Escalante-Semerena, J.
In Salmonella enterica, the sirtuin-dependent protein acylation/deacylation system (SDPADS) maintains energy homeostasis during growth on low concentrations of acetate
Mol. Microbiol.
80
168-183
2011
Salmonella enterica
Thorgersen, M.P.; Lipscomb, G.L.; Schut, G.J.; Kelly, R.M.; Adams, M.W.
Deletion of acetyl-CoA synthetases I and II increases production of 3-hydroxypropionate by the metabolically-engineered hyperthermophile Pyrococcus furiosus
Metab. Eng.
22C
83-88
2014
Pyrococcus furiosus
Berger, S.; Welte, C.; Deppenmeier, U.
Acetate activation in Methanosaeta thermophila: characterization of the key enzymes pyrophosphatase and acetyl-CoA synthetase
Archaea
2012
315153
2012
Methanothrix thermoacetophila (A0B8F1), Methanothrix thermoacetophila, Methanothrix thermoacetophila DSM 6194 (A0B8F1)
Ingram-Smith, C.; Thurman, J.L.; Zimowski, K.; Smith, K.S.
Role of motif III in catalysis by acetyl-CoA synthetase
Archaea
2012
509579
2012
Methanothermobacter thermautotrophicus (Q2I0L7)
Mayer, F.; Küper, U.; Meyer, C.; Daxer, S.; Müller, V.; Rachel, R.; Huber, H.
AMP-forming acetyl coenzyme A synthetase in the outermost membrane of the hyperthermophilic crenarchaeon Ignicoccus hospitalis
J. Bacteriol.
194
1572-1581
2012
Ignicoccus hospitalis, Ignicoccus hospitalis DSM 18386, Ignicoccus hospitalis KIN4/IT
Schäfer, T.; Schönheit, P.
Maltose fermentation to acetate, CO2 and H2 in the anaerobic hyperthermophilic archaeon Pyrococcus furiosus evidence for the operation of a novel sugar fermentation pathway
Arch. Microbiol.
158
188-202
1992
Pyrococcus furiosus
-
Liu, Y.; Zhang, M.; Wang, T.; Shi, X.; Li, J.; Jia, L.; Tang, H.; Zhang, L.
Two acetyl-CoA synthetase isoenzymes are encoded by distinct genes in marine yeast Rhodosporidium diobovatum
Biotechnol. Lett.
38
417-423
2016
Rhodotorula diobovata, Rhodotorula diobovata MCCC 2A00023
Schug, Z.T.; Peck, B.; Jones, D.T.; Zhang, Q.; Grosskurth, S.; Alam, I.S.; Goodwin, L.M.; Smethurst, E.; Mason, S.; Blyth, K.; McGarry, L.; James, D.; Shanks, E.; Kalna, G.; Saunders, R.E.; Jiang, M.; Howell, M.; Lassailly, F.; Thin, M.Z.; Spencer-Dene, B.; Stamp, G.; van den Broek, N.J.; Mackay, G.; Bulusu, V.; Kamphorst, J.J.; Tardito, S.; Strachan, D.; Harris, A.L.; Aboagye, E.O.; Critchlow, S.E.; Wakelam, M.J.; Schulze, A.; Gottlieb, E.
Acetyl-CoA synthetase 2 promotes acetate utilization and maintains cancer cell growth under metabolic stress
Cancer Cell
27
57-71
2015
Homo sapiens (Q9NR19), Homo sapiens
Mirzaei, H.; Longo, V.D.
Acetyl-CoA synthetase is a conserved regulator of autophagy and life span
Cell Metab.
19
555-557
2014
Saccharomyces cerevisiae
Bulusu, V.; Tumanov, S.; Michalopoulou, E.; van den Broek, N.J.; MacKay, G.; Nixon, C.; Dhayade, S.; Schug, Z.T.; Vande Voorde, J.; Blyth, K.; Gottlieb, E.; Vazquez, A.; Kamphorst, J.J.
Acetate recapturing by nuclear acetyl-CoA synthetase 2 prevents loss of histone acetylation during oxygen and serum limitation
Cell Rep.
18
647-658
2017
Homo sapiens (Q9NR19)
Yao, L.; Guo, X.; Gui, Y.
Acetyl-CoA synthetase 2 promotes cell migration and invasion of renal cell carcinoma by upregulating lysosomal-associated membrane protein 1 expression
Cell. Physiol. Biochem.
45
984-992
2018
Homo sapiens (Q9NR19)
Ding, J.; Holzwarth, G.; Penner, M.H.; Patton-Vogt, J.; Bakalinsky, A.T.
Overexpression of acetyl-CoA synthetase in Saccharomyces cerevisiae increases acetic acid tolerance
FEMS Microbiol. Lett.
362
1-7
2015
Saccharomyces cerevisiae (P52910), Saccharomyces cerevisiae
Han, X.; Shen, L.; Wang, Q.; Cen, X.; Wang, J.; Wu, M.; Li, P.; Zhao, W.; Zhang, Y.; Zhao, G.
Cyclic AMP inhibits the activity and promotes the acetylation of acetyl-CoA synthetase through competitive binding to the ATP/AMP pocket
J. Biol. Chem.
292
1374-1384
2017
Salmonella enterica, Salmonella enterica G2466
Tajima, K.; Han, X.; Hashimoto, Y.; Satoh, Y.; Satoh, T.; Taguchi, S.
Invitro synthesis of polyhydroxyalkanoates using thermostable acetyl-CoA synthetase, CoA transferase, and PHA synthase from thermotorelant bacteria
J. Biosci. Bioeng.
122
660-665
2016
Pelotomaculum thermopropionicum, Pelotomaculum thermopropionicum JCM10971
Jin, H.; Liang, M.; Jiang, J.
Cloning, expression, purification, and activity assay of acetyl-CoA synthetase from Dunaliella tertiolecta
Mod. Food Sci. Technol.
33
67-73
2017
Dunaliella tertiolecta
-
You, D.; Wang, M.M.; Ye, B.C.
Acetyl-CoA synthetases of Saccharopolyspora erythraea are regulated by the nitrogen response regulator GlnR at both transcriptional and post-translational levels
Mol. Microbiol.
103
845-859
2017
Saccharopolyspora erythraea, Saccharopolyspora erythraea NRRL23338
VanDrisse, C.M.; Escalante-Semerena, J.C.
In Streptomyces lividans, acetyl-CoA synthetase activity is controlled by O-serine and Nepsilon-lysine acetylation
Mol. Microbiol.
107
577-594
2018
Streptomyces lividans
Mews, P.; Donahue, G.; Drake, A.M.; Luczak, V.; Abel, T.; Berger, S.L.
Acetyl-CoA synthetase regulates histone acetylation and hippocampal memory
Nature
546
381-386
2017
Mus musculus
Tucker, A.C.; Escalante-Semerena, J.C.
Determinants within the C-terminal domain of Streptomyces lividans acetyl-CoA synthetase that block acetylation of its active site lysine in vitro by the protein acetyltransferase (Pat) enzyme
PLoS ONE
9
e99817
2014
Salmonella enterica, Streptomyces lividans
Vysochan, A.; Sengupta, A.; Weljie, A.M.; Alwine, J.C.; Yu, Y.
ACSS2-mediated acetyl-CoA synthesis from acetate is necessary for human cytomegalovirus infection
Proc. Natl. Acad. Sci. USA
114
E1528-E1535
2017
Homo sapiens (Q9NR19), Homo sapiens
Barnhart, E.P.; McClure, M.A.; Johnson, K.; Cleveland, S.; Hunt, K.A.; Fields, M.W.
Potential role of acetyl-CoA synthetase (acs) and malate dehydrogenase (mae) in the evolution of the acetate switch in Bacteria and Archaea
Sci. Rep.
5
12498
2015
Methanosarcina acetivorans
Liang, M.H.; Qv, X.Y.; Jin, H.H.; Jiang, J.G.
Characterization and expression of AMP-forming acetyl-CoA synthetase from Dunaliella tertiolecta and its response to nitrogen starvation stress
Sci. Rep.
6
23445
2016
Dunaliella tertiolecta (A0A144QFN1), Dunaliella tertiolecta
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