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Literature summary for 6.2.1.1 extracted from

  • Jetten, M.S.M.; Stams, A.J.M.; Zehnder, A.J.B.
    Isolation and characterization of acetyl-coenzyme A synthetase from Methanothrix soehngenii (1989), J. Bacteriol., 171, 5430-5435.
    View publication on PubMedView publication on EuropePMC

Inhibitors

Inhibitors Comment Organism Structure
diphosphate
-
Methanothrix soehngenii

KM Value [mM]

KM Value [mM] KM Value Maximum [mM] Substrate Comment Organism Structure
0.048
-
CoA
-
Methanothrix soehngenii
0.86
-
acetate
-
Methanothrix soehngenii

Molecular Weight [Da]

Molecular Weight [Da] Molecular Weight Maximum [Da] Comment Organism
73000
-
2 * 73000, SDS-PAGE Methanothrix soehngenii
148000
-
gel filtration Methanothrix soehngenii

Organism

Organism UniProt Comment Textmining
Methanothrix soehngenii
-
-
-

Purification (Commentary)

Purification (Comment) Organism
-
Methanothrix soehngenii

Specific Activity [micromol/min/mg]

Specific Activity Minimum [µmol/min/mg] Specific Activity Maximum [µmol/min/mg] Comment Organism
48.3
-
-
Methanothrix soehngenii

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
ATP + acetate + CoA
-
Methanothrix soehngenii AMP + diphosphate + acetyl-CoA
-
?
ATP + propanoate + CoA 5% of the activity relative to acetate Methanothrix soehngenii AMP + diphosphate + propanoyl-CoA
-
?

Subunits

Subunits Comment Organism
dimer 2 * 73000, SDS-PAGE Methanothrix soehngenii

pH Optimum

pH Optimum Minimum pH Optimum Maximum Comment Organism
8.5
-
-
Methanothrix soehngenii