Reference on EC 4.1.1.45 - aminocarboxymuconate-semialdehyde decarboxylase
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REF. 
AUTHORS
TITLE
JOURNAL
VOL.
PAGES
YEAR
ORGANISM (UNIPROT)
PUBMED ID
SOURCE
Shibata, K.
Tryptophan-niacin metabolism in alloxan diabetic rats and partial prevention of alloxan diabetes by nicotinamide
Agric. Biol. Chem.
51
811-816
1987
Rattus norvegicus
-
Shibata, K.; Hayakawa, T.; Iwai, K.
Comparison of the enzyme activities in the tryptophan-NAD pathway between the Wistar and Sprague Dawley strains of rats
Agric. Biol. Chem.
50
1643-1644
1986
Rattus norvegicus
-
Shibata, K.; Murata, K.
Comparison of the activity of the tryptophan-NAD pathway between rats fed a fat-free diet and a fat diet
Agric. Biol. Chem.
49
2899-2904
1985
Rattus norvegicus
-
Nishizuka, Y.; Ichiyama, A.; Hayaishi, O.
II. Picolinic carboxylase (cat liver) (alpha-amino-beta-carboxymuconic-epsilon-semialdehyde beta-decarboxylase)
Methods Enzymol.
17A
471-476
1970
Felis catus
-
Ichiyama, A.; Nakamura, S.; Kawai, H.; Honjo, T.; Nishizuka, Y.; Hayaishi, O.; Senoh, S.
Studies on the metabolism of the benzene ring of tryptophan in mammalian tissues II. Enzymic formation of alpha-aminomuconic acid from 3-hydroxyanthranilic acid
J. Biol. Chem.
240
740-749
1965
Felis catus
Egashira, Y.; Tanabe, A.; Ohta, T.; Sanada, H.
Dietary linoleic acid alters alpha-amino-beta-carboxymuconate-epsilon-semialdehyde decarboxylase (ACMSD), a key enzyme of niacin synthesis from tryptophan, in the process of protein expression in rat liver
J. Nutr. Sci. Vitaminol.
44
129-136
1998
BRENDA: Rattus norvegicus
Textmining: Rattus, Mus sp.
Egashira, Y.; Kouhashi, H.; Ohta, T.; Sanada, H.
Purification and properties of alpha-amino-beta-carboxymuconate-epsilon-semialdehyde decarboxylase (ACMSD), key enzyme of niacin synthesis from tryptophan, from hog kidney
J. Nutr. Sci. Vitaminol.
42
173-183
1996
Sus scrofa
Sanada, H.; Takahashi, T.; Miyazaki, M.
Effects of dietary fat and protein on the activity of alpha-amino-beta-carboxymuconate-epsilon-semialdehyde decarboxylase and the urinary excretion of niacin metabolites in rats
J. Nutr. Sci. Vitaminol.
37
39-51
1991
BRENDA: Rattus norvegicus
Textmining: collection, Glycine max, Metazoa, Rattus
Egashira, Y.; Ogawara, R.; Ohta, T.; Sanada, H.
Suppression of rat hepatic alpha-amino-beta-carboxymuconate-epsilon-semialdehyde decarboxylase (ACMSD) activity by linoleic acid in relation to its induction by glucocorticoids and dietary protein
Biosci. Biotechnol. Biochem.
58
339-343
1994
Rattus norvegicus
-
Egashira, Y.; Yamamiya, Y.; Sanada, H.
Effects of various dietary fatty acids on alpha-amino-beta-carboxymuconate-epsilon-semialdehyde decarboxylase activity in rat liver
Biosci. Biotechnol. Biochem.
56
2015-2019
1992
Rattus norvegicus
-
Fukuoka, S.; Tanabe, A.; Egashira, Y.; Sanada, H.; Shin, M.; Shibata, K.
Identification of cDNAs encoding alpha-amino-beta-carboxymuconate-epsilon-semialdehyde decarboxylase (ACMSDase)
Adv. Exp. Med. Biol.
467
615-618
1999
Caenorhabditis elegans, Homo sapiens, Mus musculus, Rattus norvegicus, Sus scrofa
Muraki, T.; Taki, M.; Hasegawa, Y.; Iwaki, H.; Lau, P.C.
Prokaryotic homologs of the eukaryotic 3-hydroxyanthranilate 3,4-dioxygenase and 2-amino-3-carboxymuconate-6-semialdehyde decarboxylase in the 2-nitrobenzoate degradation pathway of Pseudomonas fluorescens strain KU-7
Appl. Environ. Microbiol.
69
1564-1572
2003
BRENDA: Pseudomonas fluorescens (Q83V25), Pseudomonas fluorescens, Pseudomonas fluorescens KU-7 (Q83V25)
Textmining: Escherichia coli, Pseudomonas sp.
Tanabe, A.; Egashira, Y.; Fukuoka, S.; Shibata, K.; Sanada, H.
Purification and molecular cloning of rat 2-amino-3-carboxymuconate-6-semialdehyde decarboxylase
Biochem. J.
361
567-575
2002
BRENDA: Rattus norvegicus (Q8R5M5), Rattus norvegicus Wistar (Q8R5M5)
Textmining: Rattus, Homo sapiens, Mus musculus
Fukuoka, S.; Ishiguro, K.; Yanagihara, K.; Tanabe, A.; Egashira, Y.; Sanada, H.; Shibata, K.
Identification and expression of a cDNA encoding human alpha-amino-beta-carboxymuconate-epsilon-semialdehyde decarboxylase (ACMSD). A key enzyme for the tryptophan-niacine pathway and "quinolinate hypothesis"
J. Biol. Chem.
277
35162-35167
2002
Sus scrofa, Mus musculus (Q8R519), Rattus norvegicus (Q8R5M5), Homo sapiens (Q8TDX5), Homo sapiens, Mus musculus ICR (Q8R519)
Allegri, G.; Bertazzo, A.; Biasiolo, M.; Costa, C.V.; Ragazzi, E.
Kynurenine pathway enzymes in different species of animals
Adv. Exp. Med. Biol.
527
455-463
2003
Oryctolagus cuniculus, Mus sp., Rattus, Cavia, Cavia porcellus
Egashira, Y.; Murotani, G.; Tanabe, A.; Saito, K.; Uehara, K.; Morise, A.; Sato, M.; Sanada, H.
Differential effects of dietary fatty acids on rat liver alpha-amino-beta-carboxymuconate-epsilon-semialdehyde decarboxylase activity and gene expression
Biochim. Biophys. Acta
1686
118-124
2004
BRENDA: Rattus norvegicus
Textmining: Rattus
Li, T.; Walker, A.L.; Iwaki, H.; Hasegawa, Y.; Liu, A.
Kinetic and spectroscopic characterization of ACMSD from Pseudomonas fluorescens reveals a pentacoordinate mononuclear metallocofactor
J. Am. Chem. Soc.
127
12282-12290
2005
BRENDA: Pseudomonas fluorescens
Textmining: Homo sapiens
Fukuwatari, T.; Ohsaki, S.; Fukuoka, S.; Sasaki, R.; Shibata, K.
Phthalate esters enhance quinolinate production by inhibiting alpha-amino-beta-carboxymuconate-epsilon-semialdehyde decarboxylase (ACMSD), a key enzyme of the tryptophan pathway
Toxicol. Sci.
81
302-308
2004
BRENDA: Homo sapiens, Mus musculus, Rattus norvegicus
Textmining: Rattus
Allegri, G.; Ragazzi, E.; Costa, C.V.; Caparrotta, L.; Biasiolo, M.; Comai, S.; Bertazzo, A.
Tryptophan metabolism along the kynurenine pathway in diet-induced and genetic hypercholesterolemic rabbits
Clin. Chim. Acta
350
41-49
2004
Oryctolagus cuniculus, Homo sapiens, Metazoa
Comai, S.; Costa, C.V.; Ragazzi, E.; Bertazzo, A.; Allegri, G.
The effect of age on the enzyme activities of tryptophan metabolism along the kynurenine pathway in rats
Clin. Chim. Acta
360
67-80
2005
Rattus
Ragazzi, E.; Costa, C.V.; Comai, S.; Bertazzo, A.; Caparrotta, L.; Allegri, G.
Cloricromene effect on the enzyme activities of the tryptophan-nicotinic acid pathway in diabetic/hyperlipidemic rabbits
Life Sci.
78
785-794
2006
Oryctolagus cuniculus, Metazoa
Liu, A.; Zhang, H.
Transition metal-catalyzed nonoxidative decarboxylation reactions
Biochemistry
45
10407-10411
2006
Pseudomonas fluorescens
Martynowski, D.; Eyobo, Y.; Li, T.; Yang, K.; Liu, A.; Zhang, H.
Crystal structure of alpha-amino-beta-carboxymuconate-epsilon-semialdehyde decarboxylase: insight into the active site and catalytic mechanism of a novel decarboxylation reaction
Biochemistry
45
10412-10421
2006
Pseudomonas fluorescens
Li, T.; Iwaki, H.; Fu, R.; Hasegawa, Y.; Zhang, H.; Liu, A.
Alpha-amino-beta-carboxymuconic-epsilon-semialdehyde decarboxylase (ACMSD) is a new member of the amidohydrolase superfamily
Biochemistry
45
6628-6634
2006
Pseudomonas fluorescens
Pucci, L.; Perozzi, S.; Cimadamore, F.; Orsomando, G.; Raffaelli, N.
Tissue expression and biochemical characterization of human 2-amino 3-carboxymuconate 6-semialdehyde decarboxylase, a key enzyme in tryptophan catabolism
FEBS J.
274
827-840
2007
BRENDA: Homo sapiens
Textmining: Saccharomyces cerevisiae
Li, T.; Ma, J.K.; Hosler, J.P.; Davidson, V.L.; Liu, A.
Detection of transient intermediates in the metal-dependent nonoxidative decarboxylation catalyzed by alpha-amino-beta-carboxymuconate-epsilon-semialdehyde decarboxylase
J. Am. Chem. Soc.
129
9278-9279
2007
Pseudomonas fluorescens
Shin, M.; Kim, I.; Inoue, Y.; Kimura, S.; Gonzalez, F.J.
Regulation of mouse hepatic alpha-amino-beta-carboxymuconate-epsilon-semialdehyde decarboxylase, a key enzyme in the tryptophan-nicotinamide adenine dinucleotide pathway, by hepatocyte nuclear factor 4alpha and peroxisome proliferator-activated receptor alpha
Mol. Pharmacol.
70
1281-1290
2006
BRENDA: Mus musculus
Textmining: Mus sp.
Gaetjens, J.; Mullins, C.S.; Kampf, J.W.; Thuery, P.; Pecoraro, V.L.
Corroborative cobalt and zinc model compounds of alpha-amino-beta-carboxymuconic-epsilon-semialdehyde decarboxylase (ACMSD)
Dalton Trans.
2009
51-62
2009
Pseudomonas fluorescens
Sasaki, N.; Egashira, Y.; Sanada, H.
Down-regulation of alpha-amino-beta-carboxymuconate-epsilon-semialdehyde decarboxylase by polyunsaturated fatty acids in hepatocytes is not mediated by PPARalpha
Eur. J. Nutr.
47
80-86
2008
BRENDA: Rattus norvegicus
Textmining: Rattus
Sasaki, N.; Egashira, Y.; Sanada, H.
Production of L-tryptophan-derived catabolites in hepatocytes from streptozotocin-induced diabetic rats
Eur. J. Nutr.
48
145-153
2009
Rattus norvegicus
Garavaglia, S.; Perozzi, S.; Galeazzi, L.; Raffaelli, N.; Rizzi, M.
The crystal structure of human alpha-amino-beta-carboxymuconate-epsilon-semialdehyde decarboxylase in complex with 1,3-dihydroxyacetonephosphate suggests a regulatory link between NAD synthesis and glycolysis
FEBS J.
276
6615-6623
2009
BRENDA: Homo sapiens (Q8TDX5), Homo sapiens
Textmining: Transformation
Huo, L.; Fielding, A.J.; Chen, Y.; Li, T.; Iwaki, H.; Hosler, J.P.; Chen, L.; Hasegawa, Y.; Que, L.; Liu, A.
Evidence for a dual role of an active site histidine in alpha-amino-beta-carboxymuconate-epsilon-semialdehyde decarboxylase
Biochemistry
51
5811-5821
2012
BRENDA: Pseudomonas fluorescens (Q83V25), Pseudomonas fluorescens
Textmining: Electron
Matsuda, H.; Gomi, R.T.; Hirai, S.; Egashira, Y.
Effect of dietary phytol on the expression of alpha-amino-beta-carboxymuconate-epsilon-semialdehyde decarboxylase, a key enzyme of tryptophan-niacin metabolism, in rats
Biosci. Biotechnol. Biochem.
77
1416-1419
2013
BRENDA: Rattus norvegicus
Textmining: Rattus
Matsuda, H.; Sato, M.; Yakushiji, M.; Koshiguchi, M.; Hirai, S.; Egashira, Y.
Regulation of rat hepatic alpha-amino-beta-carboxymuconate-epsilon-semialdehyde decarboxylase, a key enzyme in the tryptophan-NAD pathway, by dietary cholesterol and sterol regulatory element-binding protein-2
Eur. J. Nutr.
53
469-477
2014
BRENDA: Rattus norvegicus (Q8R5M5)
Textmining: Rattus, Mammalia
Huo, L.; Davis, I.; Chen, L.; Liu, A.
The power of two: arginine 51 and arginine 239* from a neighboring subunit are essential for catalysis in alpha-amino-beta-carboxymuconate-epsilon-semialdehyde decarboxylase
J. Biol. Chem.
288
30862-30871
2013
Pseudomonas fluorescens
Pellicciari, R.; Liscio, P.; Giacche, N.; De Franco, F.; Carotti, A.; Robertson, J.; Cialabrini, L.; Katsyuba, E.; Raffaelli, N.; Auwerx, J.
alpha-Amino-beta-carboxymuconate-epsilon-semialdehyde decarboxylase (ACMSD) inhibitors as novel modulators of de novo nicotinamide adenine dinucleotide (NAD+) biosynthesis
J. Med. Chem.
61
745-759
2018
Homo sapiens (Q8TDX5)
Huo, L.; Liu, F.; Iwaki, H.; Li, T.; Hasegawa, Y.; Liu, A.
Human alpha-amino-beta-carboxymuconate-epsilon-semialdehyde decarboxylase (ACMSD) a structural and mechanistic unveiling
Proteins
83
178-187
2015
Homo sapiens (Q8TDX5)
Brundin, L.; Sellgren, C.; Lim, C.; Grit, J.; Palsson, E.; Landen, M.; Samuelsson, M.; Lundgren, K.; Brundin, P.; Fuchs, D.; Postolache, T.; Traskman-Bendz, L.; Guillemin, G.; Erhardt, S.
An enzyme in the kynurenine pathway that governs vulnerability to suicidal behavior by regulating excitotoxicity and neuroinflammation
Transl. Psychiatry
6
e865
2016
Homo sapiens (Q8TDX5), Homo sapiens
Sanada, H
Suppressive effect of dietary unsaturated fatty acids on alpha-amino-beta-carboxymuconate-epsilon-semialdehyde decarboxylase, a key enzyme of tryptophan-niacin metabolism in rat liver.
J Nutr Sci Vitaminol (Tokyo)
31
327-37
1985
Rattus, Glycine max
Sanada, H; Miyazaki, M
Effect of high-protein diet on liver alpha-amino-beta-carboxymuconate-epsilon-semialdehyde decarboxylase in rats.
J Nutr Sci Vitaminol (Tokyo)
30
113-23
1984
Rattus
Statter, M; Krieger, I
Picolinic carboxylase activity in rat liver and kidney. I. Influence of growth, sex, gestation, lactation, and nutritional imbalance.
J Pediatr Gastroenterol Nutr
2
166-70
1983
Rattus
Sanada, H; Miyazaki, M
Effect of pituitary hormones on alpha-amino-beta-carboxymuconate-epsilon-semialdehyde decarboxylase in rat.
J Nutr Sci Vitaminol (Tokyo)
26
607-16
1980
Rattus
Tanabe, A; Egashira, Y; Fukuoka, S; Shibata, K; Sanada, H
Expression of rat hepatic 2-amino-3-carboxymuconate-6-semialdehyde decarboxylase is affected by a high protein diet and by streptozotocin-induced diabetes.
J Nutr
132
1153-9
2002
Rattus, Rattus norvegicus
Fukuwatari, T; Sugimoto, E; Shibata, K
Growth-promoting activity of pyrazinoic acid, a putative active compound of antituberculosis drug pyrazinamide, in niacin-deficient rats through the inhibition of ACMSD activity.
Biosci Biotechnol Biochem
66
1435-41
2002
Rattus
IKEDA, M; TSUJI, H; NAKAMURA, S; ICHIYAMA, A; NISHIZUKA, Y; HAYAISHI, O
STUDIES ON THE BIOSYNTHESIS OF NICOTINAMIDE ADENINE DINUCLEOTIDE. II. A ROLE OF PICOLINIC CARBOXYLASE IN THE BIOSYNTHESIS OF NICOTINAMIDE ADENINE DINUCLEOTIDE FROM TRYPTOPHAN IN MAMMALS.
J Biol Chem
240
1395-401
1965
Mammalia
Fukuoka, S; Ishiguro, K; Tanabe, A; Egashira, Y; Sanada, H; Fukuwatari, T; Shibata, K
Identification and expression of alpha cDNA encoding human 2-amino-3-carboxymuconate-6-semialdehyde decarboxylase (ACMSD): a key enzyme for the tryptophan-niacine pathway and quinolinate hypothesis.
Adv Exp Med Biol
527
443-53
2003
Homo sapiens, Sus scrofa
Egashira, Y; Sato, M; Tanabe, A; Saito, K; Fujigaki, S; Sanada, H
Dietary linoleic acid suppresses gene expression of rat liver alpha-amino-beta-carboxymuconate-epsilon-semialdehyde decarboxylase (ACMSD) and increases quinolinic acid in serum.
Adv Exp Med Biol
527
671-4
2003
Rattus
Egashira, Y; Sato, M; Sato, M; Sugawara, R; Tanabe, A; Shin, M; Sanada, H
Differential effects of pyrazinamide and clofibrate on gene expression of rat hepatic alpha-amino-beta-carboxymuconate-epsilon-semialdehyde decarboxylase, a key enzyme of the tryptophan-NAD pathway.
Int J Vitam Nutr Res
76
138-46
2006
Rattus
Salter, M; Pogson, CI
The role of tryptophan 2,3-dioxygenase in the hormonal control of tryptophan metabolism in isolated rat liver cells. Effects of glucocorticoids and experimental diabetes.
Biochem J
229
499-504
1985
Rattus
Akarte, N; Shastri, N
Studies on niacin biosynthesis from 3-hydroxyanthranilic acid in streptozotocin diabetic rats in vivo and in vitro.
J Nutr Sci Vitaminol (Tokyo)
22
175-9
1976
Rattus
Satyanarayana, U; Narasinga Rao, BS
Effect of diet restriction on some key enzymes tryptophan-NAD pathway in rats.
J Nutr
107
2213-8
1977
Rattus
Rajurkar, V; Shastri, NV
Effect of ethanol ingestion on tryptophan metabolism in streptozotocin diabetic rats.
Indian J Biochem Biophys
27
339-41
1990
Rattus
Shibata, K; Motooka, K; Murata, K
The differences in growth and activity of the tryptophan-NAD pathway between Wistar and Sprague Dawley strains of rats fed on tryptophan-limited diet.
J Nutr Sci Vitaminol (Tokyo)
28
11-9
1982
Rattus
MacDonald, ML; Rogers, QR; Morris, JG
Nutrition of the domestic cat, a mammalian carnivore.
Annu Rev Nutr
4
521-62
1984
Felis catus
Johnson, WT; Evans, GW
Effects of the interrelationship between dietary protein and minerals on tissue content of trace metals in streptozotocin-diabetic rats.
J Nutr
114
180-90
1984
Rattus
Nasu, S; Yamaguchi, K; Sakakibara, S; Imai, H; Ueda, I
The effect of pyrazines on the metabolism of tryptophan and nicotinamide adenine dinucleotide in the rat. Evidence of the formation of a potent inhibitor of aminocarboxy-muconate-semialdehyde decarboxylase from pyrazinamide.
Biochim Biophys Acta
677
109-19
1981
Rattus
Bender, DA
Effects of a dietary excess of leucine on the metabolism of tryptophan in the rat: a mechanism for the pellagragenic action of leucine.
Br J Nutr
50
25-32
1983
Rattus, Homo sapiens, Metazoa
Egashira, Y; Nakazawa, A; Ohta, T; Shibata, K; Sanada, H
Effect of dietary linoleic acid on the tryptophan-niacin metabolism in streptozotocin diabetic rats.
Comp Biochem Physiol A Physiol
111
539-45
1995
Rattus
Egashira, Y; Komine, T; Ohta, T; Shibata, K; Sanada, H
Change of tryptophan-niacin metabolism in D-galactosamine-induced liver injury in rat.
J Nutr Sci Vitaminol (Tokyo)
43
233-9
1997
Rattus
Shibata, K; Ishikawa, A; Kondo, T
Effects of dietary pyrazinamide on the metabolism of tryptophan to niacin in streptozotocin-diabetic rats.
Biosci Biotechnol Biochem
61
1679-83
1997
Rattus
Shin, M; Iwamoto, N; Yamashita, M; Sano, K; Umezawa, C
Pyridine nucleotide levels in liver of rats fed clofibrate- or pyrazinamide-containing diets.
Biochem Pharmacol
55
367-71
1998
Rattus, Metazoa
Bertazzo, A; Ragazzi, E; Biasiolo, M; Costa, CV; Allegri, G
Enzyme activities involved in tryptophan metabolism along the kynurenine pathway in rabbits.
Biochim Biophys Acta
1527
167-75
2001
Oryctolagus cuniculus
Ragazzi, E; Costa, CV; Caparrotta, L; Biasiolo, M; Bertazzo, A; Allegri, G
Enzyme activities along the tryptophan-nicotinic acid pathway in alloxan diabetic rabbits.
Biochim Biophys Acta
1571
9-17
2002
Oryctolagus cuniculus, animal
Fukuwatari, T; Suzuki, Y; Sugimoto, E; Shibata, K
Identification of a toxic mechanism of the plasticizers, phtahlic acid esters, which are putative endocrine disrupters: time-dependent increase in quinolinic acid and its metabolites in rats fed di(2-ethylhexyl)phthalate.
Biosci Biotechnol Biochem
66
2687-91
2002
Rattus
Ringeissen, S; Connor, SC; Brown, HR; Sweatman, BC; Hodson, MP; Kenny, SP; Haworth, RI; McGill, P; Price, MA; Aylott, MC; Nunez, DJ; Haselden, JN; Waterfield, CJ
Potential urinary and plasma biomarkers of peroxisome proliferation in the rat: identification of N-methylnicotinamide and N-methyl-4-pyridone-3-carboxamide by 1H nuclear magnetic resonance and high performance liquid chromatography.
Biomarkers
8
240-71
0
Rattus, Metazoa
Allegri, G; Costa, CV; Bertazzo, A; Biasiolo, M; Ragazzi, E
Enzyme activities of tryptophan metabolism along the kynurenine pathway in various species of animals.
Farmaco
58
829-36
2003
Oryctolagus cuniculus, Cavia porcellus
Fukuwatari, T; Ohta, M; Sugimoto, E; Sasaki, R; Shibata, K
Effects of dietary di(2-ethylhexyl)phthalate, a putative endocrine disrupter, on enzyme activities involved in the metabolism of tryptophan to niacin in rats.
Biochim Biophys Acta
1672
67-75
2004
Rattus
Allegri, G; Ragazzi, E; Costa, CV; Caparrotta, L; Biasiolo, M; Vanin, S
The kynurenine pathway enzymes in healthy and hyperlipidemic rabbits.
Adv Exp Med Biol
527
381-6
2003
Oryctolagus cuniculus
Allegri, G; Zaccarin, D; Ragazzi, E; Froldi, G; Bertazzo, A; Costa, CV
Metabolism of tryptophan along the kynurenine pathway in alloxan diabetic rabbits.
Adv Exp Med Biol
527
387-93
2003
Oryctolagus cuniculus
Allegri, G; Ragazzi, E; Bertazzo, A; Costa, CV; Rocchi, R
Tryptophan metabolism along the kynurenine pathway in rats.
Adv Exp Med Biol
527
481-96
2003
Rattus
Connor, SC; Hodson, MP; Ringeissen, S; Sweatman, BC; McGill, PJ; Waterfield, CJ; Haselden, JN
Development of a multivariate statistical model to predict peroxisome proliferation in the rat, based on urinary 1H-NMR spectral patterns.
Biomarkers
9
364-85
0
Rattus
Egashira, Y; Nagaki, S; Sanada, H
Tryptophan-niacin metabolism in rat with puromycin aminonucleoside-induced nephrosis.
Int J Vitam Nutr Res
76
28-33
2006
Rattus, collection
Egashira, Y; Sato, M; Saito, K; Sanada, H
Dietary protein level and dietary interaction affect quinolinic acid concentration in rats.
Int J Vitam Nutr Res
77
142-8
2007
Rattus
Matsuda, H; Sato, M; Yakushiji, M; Koshiguchi, M; Hirai, S; Egashira, Y
Regulation of rat hepatic ?-amino-?-carboxymuconate-?-semialdehyde decarboxylase, a key enzyme in the tryptophan-NAD pathway, by dietary cholesterol and sterol regulatory element-binding protein-2.
Eur J Nutr
2013
Rattus
Shibata, K; Fukuwatari, T
Large amounts of picolinic Acid are lethal but small amounts increase the conversion of tryptophan-nicotinamide in rats.
J Nutr Sci Vitaminol (Tokyo)
60
334-9
2014
Rattus
Koshiguchi, M; Hirai, S; Egashira, Y
PGC1? regulates ACMSD expression through cooperation with HNF4?.
Amino Acids
50
1769-1773
2018
Yoshino, J
ACMSD: A Novel Target for Modulating NAD+ Homeostasis.
Trends Endocrinol Metab
2019
Homo sapiens, Mus sp.
Satyanarayana, U; Rao, BS
Effect of dietary protein level on some key enzymes of the tryptophan-NAD pathway.
Br J Nutr
38
39-45
1977
Rattus
Shin, M; Sano, K; Umezawa, C
Effects of peroxisome-proliferators on the TRP-NAD pathway.
Adv Exp Med Biol
467
333-40
1999
Rattus
Saito, K; Fujigaki, S; Heyes, MP; Shibata, K; Takemura, M; Fujii, H; Wada, H; Noma, A; Seishima, M
Mechanism of increases in L-kynurenine and quinolinic acid in renal insufficiency.
Am J Physiol Renal Physiol
279
F565-72
2000
Rattus, Homo sapiens
Ohashi, H; Saito, K; Fujii, H; Wada, H; Furuta, N; Takemura, M; Maeda, S; Seishima, M
Changes in quinolinic acid production and its related enzymes following D-galactosamine and lipopolysaccharide-induced hepatic injury.
Arch Biochem Biophys
428
154-9
2004
Homo sapiens, Gerbillinae, animal
Delaney, J; Hodson, MP; Thakkar, H; Connor, SC; Sweatman, BC; Kenny, SP; McGill, PJ; Holder, JC; Hutton, KA; Haselden, JN; Waterfield, CJ
Tryptophan-NAD+ pathway metabolites as putative biomarkers and predictors of peroxisome proliferation.
Arch Toxicol
79
208-23
2005
Rattus
Katsyuba, E; Mottis, A; Zietak, M; De Franco, F; van der Velpen, V; Gariani, K; Ryu, D; Cialabrini, L; Matilainen, O; Liscio, P; Giacch, N; Stokar-Regenscheit, N; Legouis, D; de Seigneux, S; Ivanisevic, J; Raffaelli, N; Schoonjans, K; Pellicciari, R; Auwerx, J
De novo NAD+ synthesis enhances mitochondrial function and improves health.
Nature
563
354-359
2018
Caenorhabditis elegans, Mus musculus
Palzer, L; Bader, JJ; Angel, F; Witzel, M; Blaser, S; McNeil, A; Wandersee, MK; Leu, NA; Lengner, CJ; Cho, CE; Welch, KD; Kirkland, JB; Meyer, RG; Meyer-Ficca, ML
Alpha-Amino-Beta-Carboxy-Muconate-Semialdehyde Decarboxylase Controls Dietary Niacin Requirements for NAD+ Synthesis.
Cell Rep
25
1359-1370.e4
2018
Homo sapiens, Mus musculus
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