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Literature summary for 4.1.1.45 extracted from

  • Matsuda, H.; Gomi, R.T.; Hirai, S.; Egashira, Y.
    Effect of dietary phytol on the expression of alpha-amino-beta-carboxymuconate-epsilon-semialdehyde decarboxylase, a key enzyme of tryptophan-niacin metabolism, in rats (2013), Biosci. Biotechnol. Biochem., 77, 1416-1419.
    View publication on PubMed
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Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
2-amino-3-(3-oxoprop-1-en-1-yl)but-2-enedioate Rattus norvegicus
-
 2-aminomuconate semialdehyde + CO2
-
 ?

Organism

Organism UniProt Comment Textmining
Rattus norvegicus
-
-
-

Source Tissue

Source Tissue Comment Organism Textmining
liver
-
 Rattus norvegicus
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
2-amino-3-(3-oxoprop-1-en-1-yl)but-2-enedioate
-
 Rattus norvegicus 2-aminomuconate semialdehyde + CO2
-
 ?

Synonyms

Synonyms Comment Organism
ACMSD
-
 Rattus norvegicus
alpha-amino-beta-carboxymuconate-epsilon-semialdehyde decarboxylase
-
 Rattus norvegicus

Expression

Organism Comment Expression
Rattus norvegicus enzyme mRNA expression and activity is decreased by phytol in a dose-dependent manner (80% at 0.1 mM) down