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Literature summary for 4.1.1.45 extracted from

  • Li, T.; Ma, J.K.; Hosler, J.P.; Davidson, V.L.; Liu, A.
    Detection of transient intermediates in the metal-dependent nonoxidative decarboxylation catalyzed by alpha-amino-beta-carboxymuconate-epsilon-semialdehyde decarboxylase (2007), J. Am. Chem. Soc., 129, 9278-9279.
    View publication on PubMed
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Metals/Ions

Metals/Ions Comment Organism Structure
Co2+ after purification, Co2+-reconstituted ACMSD exhibits the highest activity and the greatest stability Pseudomonas fluorescens
Mn2+
-
 Pseudomonas fluorescens

Organism

Organism UniProt Comment Textmining
Pseudomonas fluorescens
-
-
-

Reaction

Reaction Comment Organism Reaction ID
2-amino-3-(3-oxoprop-1-en-1-yl)but-2-enedioate = 2-aminomuconate semialdehyde + CO2 the decarboxylation occurs first to generate an unstable alpha-aminomuconate-epsilon-semialdehyde intermediate, which then undergoes a relatively slow release from the enzyme and a much slower cyclization to yield the final product Pseudomonas fluorescens
a

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
2-amino-3-(3-oxoprop-2-enyl)-but-2-enedioate the decarboxylation occurs first to generate an unstable alpha-aminomuconate-epsilon-semialdehyde intermediate, which then undergoes a relatively slow release from the enzyme and a much slower cyclization to yield the final product Pseudomonas fluorescens 2-aminomuconate-6-semialdehyde + CO2
-
 ?

Synonyms

Synonyms Comment Organism
ACMSD
-
 Pseudomonas fluorescens
alpha-amino-beta-carboxymuconate-epsilon-semialdehyde decarboxylase
-
 Pseudomonas fluorescens