Reference on EC 3.6.1.62 - 5'-(N7-methylguanosine 5'-triphospho)-[mRNA] hydrolase
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REF. 
AUTHORS
TITLE
JOURNAL
VOL.
PAGES
YEAR
ORGANISM (UNIPROT)
PUBMED ID
SOURCE
Ghosh, T.; Peterson, B.; Tomasevic, N.; Peculis, B.A.
Xenopus U8 snoRNA binding protein is a conserved nuclear decapping enzyme
Mol. Cell
13
817-828
2004
Homo sapiens, Xenopus laevis (Q6TEC1)
Zhang, J.; Gao, F.; Zhang, Q.; Chen, Q.; Qi, J.; Yan, J.
Crystallization and crystallographic analysis of human NUDT16
Acta Crystallogr. Sect. F
64
639-640
2008
Homo sapiens
Soulire, M.F.; Perreault, J.P.; Bisaillon. M.
Characterization of the vaccinia virus D10 decapping enzyme provides evidence for a two-metal-ion mechanism
Biochem. J.
420
27-35
2009
Vaccinia virus
van Dijk, E.; Cougot, N.; Meyer, S.; Babajko, S.; Wahle, E.; Sraphin, B.
Human Dcp2: a catalytically active mRNA decapping enzyme located in specific cytoplasmic structures
EMBO J.
21
6915-6924
2002
Saccharomyces cerevisiae (P53550), Saccharomyces cerevisiae, Homo sapiens (Q8IU60), Homo sapiens
Peculis, B.A.; Reynolds, K.; Cleland, M.
Metal determines efficiency and substrate specificity of the nuclear NUDIX decapping proteins X29 and H29K (Nudt16)
J. Biol. Chem.
282
24792-24805
2007
Xenopus laevis (Q6TEC1), Homo sapiens (Q96DE0), Homo sapiens
Parrish, S.; Moss, B.
Characterization of a second vaccinia virus mRNA-decapping enzyme conserved in poxviruses
J. Virol.
81
12973-12978
2007
Vaccinia virus
Lykke-Andersen, J.
Identification of a human decapping complex associated with hUpf proteins in nonsense-mediated decay
Mol. Cell. Biol.
22
8114-8121
2002
Homo sapiens (Q8IU60), Homo sapiens
Song, M.G.; Li, Y.; Kiledjian, M.
Multiple mRNA decapping enzymes in mammalian cells
Mol. Cell.
40
423-432
2010
Mus musculus (Q6P3D0), Mus musculus (Q9CYC6), Mus musculus, Homo sapiens (Q8IU60), Homo sapiens (Q96DE0), Homo sapiens
Li, Y.; Ho, E.S.; Gunderson, S.I.; Kiledjian, M.
Mutational analysis of a Dcp2-binding element reveals general enhancement of decapping by 5'-end stem-loop structures
Nucleic Acids Res.
37
2227-2237
2009
Homo sapiens
Xu, J.; Yang, J.Y.; Niu, Q.W.; Chua, N.H.
Arabidopsis DCP2, DCP1, and VARICOSE form a decapping complex required for postembryonic development
Plant Cell
18
3386-3398
2006
Arabidopsis thaliana
Parrish, S.; Resch, W.; Moss, B.
Vaccinia virus D10 protein has mRNA decapping activity, providing a mechanism for control of host and viral gene expression
Proc. Natl. Acad. Sci. USA
104
2139-2144
2007
Vaccinia virus
Wang, Z.; Jiao, X.; Carr-Schmid, A.; Kiledjian, M.
The hDcp2 protein is a mammalian mRNA decapping enzyme
Proc. Natl. Acad. Sci. USA
99
12663-12668
2002
Homo sapiens (Q8IU60), Homo sapiens
Lu, G.; Zhang, J.; Li, Y.; Li, Z.; Zhang, N.; Xu, X.; Wang, T.; Guan, Z.; Gao, G.F.; Yan, J.
hNUDT16: a universal decapping enzyme for small nucleolar RNA and cytoplasmic mRNA
Protein Cell
2
64-73
2011
Homo sapiens
Liu, S.W.; Jiao, X.; Liu, H.; Gu, M.; Lima, C.D.; Kiledjian, M.
Functional analysis of mRNA scavenger decapping enzymes
RNA
10
1412-1422
2004
Homo sapiens (Q8IU60)
Scarsdale, J.N.; Peculis, B.A.; Wright, H.T.
Crystal structures of U8 snoRNA decapping nudix hydrolase, X29, and its metal and cap complexes
Structure
14
331-343
2006
Xenopus laevis (Q6TEC1), Xenopus laevis
Fromm, S.; Truffault, V.; Kamenz, J.; Braun, J.; Hoffmann, N.; Izaurralde, E.; Sprangers, R.
The structural basis of Edc3-and Scd6-mediated activation of the Dcp1:Dcp2 mRNA decapping complex
EMBO J.
31
279-290
2012
Schizosaccharomyces pombe (O13828), Schizosaccharomyces pombe ATCC 24843 (O13828)
Li, Y.; Dai, J.; Song, M.; Fitzgerald-Bocarsly, P.; Kiledjian, M.
Dcp2 decapping protein modulates mRNA stability of the critical interferon regulatory factor (IRF) IRF-7
Mol. Cell. Biol.
32
1164-1172
2012
Mus musculus (Q9CYC6)
Geisler, S.; Lojek, L.; Khalil, A.; Baker, K.; Coller, J.
Decapping of long noncoding RNAs regulates inducible genes
Mol. Cell.
45
279-291
2012
Saccharomyces cerevisiae (P53550)
Floor, S.; Borja, M.; Gross, J.
Interdomain dynamics and coactivation of the mRNA decapping enzyme Dcp2 are mediated by a gatekeeper tryptophan
Proc. Natl. Acad. Sci. USA
109
2872-2877
2012
Schizosaccharomyces pombe (O13828), Schizosaccharomyces pombe, Saccharomyces cerevisiae (P53550), Saccharomyces cerevisiae, Schizosaccharomyces pombe ATCC 24843 (O13828)
Aglietti, R.A.; Floor, S.N.; McClendon, C.L.; Jacobson, M.P.; Gross, J.D.
Active site conformational dynamics are coupled to catalysis in the mRNA decapping enzyme Dcp2
Structure
21
1571-1580
2013
Saccharomyces cerevisiae (P53550)
Burgess, H.M.; Pourchet, A.; Hajdu, C.H.; Chiriboga, L.; Frey, A.B.; Mohr, I.
Targeting poxvirus decapping enzymes and mRNA decay to generate an effective oncolytic virus
Mol. Ther. Oncolytics
8
71-81
2018
Vaccinia virus
Tresaugues, L.; Lundbaeck, T.; Welin, M.; Flodin, S.; Nyman, T.; Silvander, C.; Graeslund, S.; Nordlund, P.
Structural basis for the specificity of human NUDT16 and its regulation by inosine monophosphate
PLoS ONE
10
e0131507
2015
Homo sapiens (Q96DE0), Homo sapiens
Grudzien-Nogalska, E.; Jiao, X.; Song, M.G.; Hart, R.P.; Kiledjian, M.
Nudt3 is an mRNA decapping enzyme that modulates cell migration
RNA
22
773-781
2016
Homo sapiens
Grzela, R.; Nasilowska, K.; Lukaszewicz, M.; Tyras, M.; Stepinski, J.; Jankowska-Anyszka, M.; Bojarska, E.; Darzynkiewicz, E.
Hydrolytic activity of human Nudt16 enzyme on dinucleotide cap analogs and short capped oligonucleotides
RNA
24
633-642
2018
Homo sapiens
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