Crystallization (Comment) | Organism |
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structure of the yeast enhancer of mRNA-decapping protein Edc3 LSm domain in complex with a short helical leucine-rich motif from subunit Dcp2. The motif interacts with the monomeric Edc3 LSm domain and recognizes a noncanonical binding surface. Additional helical leucine-rich motifs in the disordered C-terminal extension of Dcp2 can interact with Edc3. Both Edc3 and Scd6 stimulate decapping in vitro, presumably by preventing the Dcp1:Dcp2 complex from adopting an inactive conformation. The C-terminal helical leucine-rich motifs in Dcp2 are necessary for the localization of the Dcp1:Dcp2 decapping complex to P-bodies in vivo | Schizosaccharomyces pombe |
Organism | UniProt | Comment | Textmining |
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Schizosaccharomyces pombe | O13828 | - |
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Schizosaccharomyces pombe ATCC 24843 | O13828 | - |
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