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Literature summary for 3.6.1.62 extracted from

  • Grudzien-Nogalska, E.; Kiledjian, M.
    New insights into decapping enzymes and selective mRNA decay (2017), Wiley Interdiscip. Rev. RNA, 8, e1379 .
    View publication on PubMedView publication on EuropePMC
Search for more literature for 3.6.1.62

Activating Compound

Activating Compound Comment Organism Structure
Dcp1
-
 Homo sapiens
Dcp1
-
 Saccharomyces cerevisiae
Dhh1p
-
 Homo sapiens
Dhh1p
-
 Saccharomyces cerevisiae
Edc1p
-
 Homo sapiens
Edc1p
-
 Saccharomyces cerevisiae
Edc2p
-
 Homo sapiens
Edc2p
-
 Saccharomyces cerevisiae
Edc3p
-
 Homo sapiens
Edc3p
-
 Saccharomyces cerevisiae
Hedls protein also known as Edc4 or Ge-1 Homo sapiens
Hedls protein also known as Edc4 or Ge-1 Saccharomyces cerevisiae
Lsm1p-7p complex
-
 Homo sapiens
Lsm1p-7p complex
-
 Saccharomyces cerevisiae
Pat1p
-
 Homo sapiens
Pat1p
-
 Saccharomyces cerevisiae
tristetraprolin
-
 Homo sapiens
tristetraprolin
-
 Saccharomyces cerevisiae
Upf1p
-
 Homo sapiens
Upf1p
-
 Saccharomyces cerevisiae

Localization

Localization Comment Organism GeneOntology No. Textmining
nucleus
-
 Homo sapiens 5634
-
nucleus
-
 Saccharomyces cerevisiae 5634
-

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
a 5'-(N7-methylguanosine 5'-triphospho)-[mRNA] + H2O Homo sapiens
-
 N7-methylguanosine 5'-diphosphate + a 5'-phospho-[mRNA]
-
 ?
a 5'-(N7-methylguanosine 5'-triphospho)-[mRNA] + H2O Saccharomyces cerevisiae
-
 N7-methylguanosine 5'-diphosphate + a 5'-phospho-[mRNA]
-
 ?

Organism

Organism UniProt Comment Textmining
Homo sapiens
-
-
-
Saccharomyces cerevisiae
-
-
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
a 5'-(N7-methylguanosine 5'-triphospho)-[mRNA] + H2O
-
 Homo sapiens N7-methylguanosine 5'-diphosphate + a 5'-phospho-[mRNA]
-
 ?
a 5'-(N7-methylguanosine 5'-triphospho)-[mRNA] + H2O
-
 Saccharomyces cerevisiae N7-methylguanosine 5'-diphosphate + a 5'-phospho-[mRNA]
-
 ?

Synonyms

Synonyms Comment Organism
Dcp1p regulatory subunit Saccharomyces cerevisiae
Dcp2
-
 Saccharomyces cerevisiae
Dcp2p catalytic subunit Saccharomyces cerevisiae
Nudt16
-
 Homo sapiens
Nudt17
-
 Homo sapiens
Nudt19
-
 Homo sapiens
Nudt20
-
 Saccharomyces cerevisiae
U8 snoRNA binding protein
-
 Homo sapiens

General Information

General Information Comment Organism
physiological function the enzyme regulates mRNA stability in cells Homo sapiens
physiological function the enzyme regulates mRNA stability in cells Saccharomyces cerevisiae