Reference on EC 1.11.1.9 - glutathione peroxidase and Organism(s) Homo sapiens and UniProt Accession Q96SL4
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AUTHORS
TITLE
JOURNAL
VOL.
PAGES
YEAR
ORGANISM (UNIPROT)
PUBMED ID
SOURCE
Charmagnol, F.; Sinet, P.M.; Jerome, H.
Selenium-dependent and non-selenium-dependent glutathione peroxidases in human tissue extracts
Biochim. Biophys. Acta
759
49-57
1983
Homo sapiens
Awasthi, Y.C.; Dao, D.D.; Lal, A.K.; Srivastava, S.K.
Purification and properties of glutathione peroxidase from human placenta
Biochem. J.
177
471-476
1979
Homo sapiens
Tan, M.; Li, S.; Swaroop, M.; Guan, K.; Oberley, L.W.; Sun, Y.
Transcriptional activation of the human glutathione peroxidase promoter by p53
J. Biol. Chem.
274
12061-12066
1999
Homo sapiens
Chu, F.F.; Doroshow, J.H.; Esworthy, R.S.
Expression, characterization, and tissue distribution of a new cellular selenium-dependent glutathione peroxidase, GSHPx-GI
J. Biol. Chem.
268
2571-2576
1993
Homo sapiens
Rey, C.; Vericel, E.; Nemoz, G.; Chen, W.; Chapuy, P.; Lagarde, M.
Purification and characterization of glutathione peroxidase from human blood platelets. Age-related changes in the enzyme
Biochim. Biophys. Acta
1226
219-224
1994
Homo sapiens
Januel, C.; Fay, L.B.; Ruggiero, D.; Lagarde, M.; Vericel, E.
Covalent coupling of reduced glutathione with ribose: loss of cosubstrate ability to glutathione peroxidase
Biochim. Biophys. Acta
1620
125-132
2003
Homo sapiens
Suzuki, K.; Koike, H.; Matsui, H.; Ono, Y.; Hasumi, M.; Nakazato, H.; Okugi, H.; Sekine, Y.; Oki, K.; Ito, K.; Yamamoto, T.; Fukabori, Y.; Kurokawa, K.; Yamanaka, H.
Genistein, a soy isoflavone, induces glutathione peroxidase in the human prostate cancer cell lines LNCaP and PC-3
Int. J. Cancer
99
846-852
2002
Homo sapiens
Ran, Q.; Liang, H.; Gu, M.; Qi, W.; Walter, C.A.; Roberts, L.J.2nd.; Herman, B.; Richardson, A.; Van Remmen, H.
Transgenic mice overexpressing glutathione peroxidase 4 are protected against oxidative stress-induced apoptosis
J. Biol. Chem.
279
55137-55146
2004
Homo sapiens
Stephensen, C.B.; Marquis, G.S.; Douglas, S.D.; Kruzich, L.A.; Wilson, C.M.
Glutathione, glutathione peroxidase, and selenium status in HIV-positive and HIV-negative adolescents and young adults
Am. J. Clin. Nutr.
85
173-181
2007
Homo sapiens
Kaynar, H.; Meral, M.; Turhan, H.; Keles, M.; Celik, G.; Akcay, F.
Glutathione peroxidase, glutathione-S-transferase, catalase, xanthine oxidase, Cu-Zn superoxide dismutase activities, total glutathione, nitric oxide, and malondialdehyde levels in erythrocytes of patients with small cell and non-small cell lung cancer
Cancer Lett.
227
133-139
2005
Homo sapiens
Zhang, Y.; Handy, D.E.; Loscalzo, J.
Adenosine-dependent induction of glutathione peroxidase 1 in human primary endothelial cells and protection against oxidative stress
Circ. Res.
96
831-837
2005
Homo sapiens
McLean, C.W.; Mirochnitchenko, O.; Claus, C.P.; Noble-Haeusslein, L.J.; Ferriero, D.M.
Overexpression of glutathione peroxidase protects immature murine neurons from oxidative stress
Dev. Neurosci.
27
169-175
2005
Homo sapiens, Mus musculus
Mysore, T.B.; Shinkel, T.A.; Collins, J.; Salvaris, E.J.; Fisicaro, N.; Murray-Segal, L.J.; Johnson, L.E.; Lepore, D.A.; Walters, S.N.; Stokes, R.; Chandra, A.P.; OConnell, P.J.; dApice, A.J.; Cowan, P.J.
Overexpression of glutathione peroxidase with two isoforms of superoxide dismutase protects mouse islets from oxidative injury and improves islet graft function
Diabetes
54
2109-2116
2005
Homo sapiens
Steinbrenner, H.; Bilgic, E.; Alili, L.; Sies, H.; Brenneisen, P.
Selenoprotein P protects endothelial cells from oxidative damage by stimulation of glutathione peroxidase expression and activity
Free Radic. Res.
40
936-943
2006
Homo sapiens
Romanowska, M.; Kikawa, K.D.; Fields, J.R.; Maciag, A.; North, S.L.; Shiao, Y.H.; Kasprzak, K.S.; Anderson, L.M.
Effects of selenium supplementation on expression of glutathione peroxidase isoforms in cultured human lung adenocarcinoma cell lines
Lung Cancer
55
35-42
2007
Homo sapiens
Drevet, J.R.
The antioxidant glutathione peroxidase family and spermatozoa: a complex story
Mol. Cell. Endocrinol.
250
70-79
2006
Bos taurus, Canis lupus familiaris, Oryctolagus cuniculus, Homo sapiens, Mus musculus, Rattus norvegicus, Sus scrofa
Yang, M.S.; Chan, H.W.; Yu, L.C.
Glutathione peroxidase and glutathione reductase activities are partially responsible for determining the susceptibility of cells to oxidative stress
Toxicology
226
126-130
2006
Homo sapiens, Mus musculus, Rattus norvegicus
Toppo, S.; Vanin, S.; Bosello, V.; Tosatto, S.C.
Evolutionary and structural insights into the multifaceted glutathione peroxidase (Gpx) superfamily
Antioxid. Redox Signal.
10
1501-1514
2008
Homo sapiens (O75715), Homo sapiens (P07203), Homo sapiens (P18283), Homo sapiens (P22352), Homo sapiens (P59796), Homo sapiens (Q6PI42), Homo sapiens (Q8TED1), Homo sapiens (Q96SL4)
Bertelsmann, H.; Kuehbacher, M.; Weseloh, G.; Kyriakopoulos, A.; Behne, D.
Sperm nuclei glutathione peroxidases and their occurrence in animal species with cysteine-containing protamines
Biochim. Biophys. Acta
1770
1459-1467
2007
Equus caballus, Homo sapiens, no activity in Gallus gallus, Rattus norvegicus, no activity in Onchorhynchus mykiss
Schmutzler, C.; Mentrup, B.; Schomburg, L.; Hoang-Vu, C.; Herzog, V.; Koehrle, J.
Selenoproteins of the thyroid gland: expression, localization and possible function of glutathione peroxidase 3
Biol. Chem.
388
1053-1059
2007
Homo sapiens (P07203), Homo sapiens (P22352), Homo sapiens (Q6PI42)
Liu, L.; Mao, S.Z.; Liu, X.M.; Huang, X.; Xu, J.Y.; Liu, J.Q.; Luo, G.M.; Shen, J.C.
Functional mimicry of the active site of glutathione peroxidase by glutathione imprinted selenium-containing protein
Biomacromolecules
9
363-368
2008
Homo sapiens
Yu, Y.P.; Yu, G.; Tseng, G.; Cieply, K.; Nelson, J.; Defrances, M.; Zarnegar, R.; Michalopoulos, G.; Luo, J.H.
Glutathione peroxidase 3, deleted or methylated in prostate cancer, suppresses prostate cancer growth and metastasis
Cancer Res.
67
8043-8050
2007
Homo sapiens (P22352)
Robertson, R.P.; Harmon, J.S.
Pancreatic islet beta-cell and oxidative stress: the importance of glutathione peroxidase
FEBS Lett.
581
3743-3748
2007
Homo sapiens, Rattus norvegicus
Zheng, K.; Board, P.G.; Fei, X.; Sun, Y.; Lv, S.; Yan, G.; Liu, J.; Shen, J.; Luo, G.
A novel selenium-containing glutathione transferase zeta1-1, the activity of which surpasses the level of some native glutathione peroxidases
Int. J. Biochem. Cell Biol.
40
2090-2097
2008
Homo sapiens
Barschak, A.G.; Sitta, A.; Deon, M.; Barden, A.T.; Schmitt, G.O.; Dutra-Filho, C.S.; Wajner, M.; Vargas, C.R.
Erythrocyte glutathione peroxidase activity and plasma selenium concentration are reduced in maple syrup urine disease patients during treatment
Int. J. Dev. Neurosci.
25
335-338
2007
Homo sapiens
Prasad, C.V.; Kodliwadmath, M.V.; Kodliwadmath, G.B.
Erythrocyte glutathione peroxidase, glutathione reductase activities and blood glutathione content in leprosy
J. Infect.
56
469-473
2008
Homo sapiens
Huo, R.; Wei, J.; Xu, J.; Lv, S.; Zheng, Q.; Yan, F.; Su, J.; Fan, J.; Li, J.; Duan, Y.; Yu, Y.; Jin, F.; Sun, W.; Shi, Y.; Cong, D.; Li, W.; Yan, G.; Luo, G.
Human catalytic antibody Se-scFv-B3 with high glutathione peroxidase activity
J. Mol. Recognit.
21
324-329
2008
Homo sapiens
Ding, W.Q.; Lind, S.E.
Phospholipid hydroperoxide glutathione peroxidase plays a role in protecting cancer cells from docosahexaenoic acid-induced cytotoxicity
Mol. Cancer Ther.
6
1467-1474
2007
Homo sapiens
Jacobson, G.A.; Yee, K.C.; Ng, C.H.
Elevated plasma glutathione peroxidase concentration in acute severe asthma: comparison with plasma glutathione peroxidase activity, selenium and malondialdehyde
Scand. J. Clin. Lab. Invest.
67
423-430
2007
Homo sapiens
Tsuru-Aoyagi, K.; Potts, M.B.; Trivedi, A.; Pfankuch, T.; Raber, J.; Wendland, M.; Claus, C.P.; Koh, S.E.; Ferriero, D.; Noble-Haeusslein, L.J.
Glutathione peroxidase activity modulates recovery in the injured immature brain
Ann. Neurol.
65
540-549
2009
Homo sapiens
Ha, E.J.; Smith, A.M.
Selenium-dependent glutathione peroxidase activity is increased in healthy post-menopausal women
Biol. Trace Elem. Res.
131
90-95
2009
Homo sapiens
Bae, Y.; Cai, G.; Kim, S.; Zo, Y.; Kong, Y.
Modular evolution of glutathione peroxidase genes in association with different biochemical properties of their encoded proteins in invertebrate animals
BMC Evol. Biol.
9
72
2009
Homo sapiens (P07203), Homo sapiens (P22352), Brugia pahangi (P67878), Schistosoma mansoni (Q00277), Paragonimus westermani (Q1PBM0), Paragonimus westermani (Q1PBM1), Schistosoma japonicum (Q86EQ5)
Espinoza, S.E.; Guo, H.; Fedarko, N.; DeZern, A.; Fried, L.P.; Xue, Q.L.; Leng, S.; Beamer, B.; Walston, J.D.
Glutathione peroxidase enzyme activity in aging
J. Gerontol. A Biol. Sci. Med. Sci.
63
505-509
2008
Homo sapiens
He, T.; Joyner, M.J.; Katusic, Z.S.
Aging decreases expression and activity of glutathione peroxidase-1 in human endothelial progenitor cells
Microvasc. Res.
78
447-452
2009
Homo sapiens
Chung, S.S.; Kim, M.; Youn, B.S.; Lee, N.S.; Park, J.W.; Lee, I.K.; Lee, Y.S.; Kim, J.B.; Cho, Y.M.; Lee, H.K.; Park, K.S.
Glutathione peroxidase 3 mediates the antioxidant effect of peroxisome proliferator-activated receptor gamma in human skeletal muscle cells
Mol. Cell. Biol.
29
20-30
2009
Homo sapiens
Takata, Y.; Morris, J.S.; King, I.B.; Kristal, A.R.; Lin, D.W.; Peters, U.
Correlation between selenium concentrations and glutathione peroxidase activity in serum and human prostate tissue
Prostate
69
1635-1642
2009
Homo sapiens
Yang, W.H.; Park, S.Y.; Ji, S.; Kang, J.G.; Kim, J.-E.; Song, H.; Mook-Jung, I.; Choe, K.-M.; Cho, J.W.
O-GlcNAcylation regulates hyperglycemia-induced GPX1 activation
Biochem. Biophys. Res. Commun.
391
756-761
2010
Homo sapiens, Mus musculus, Rattus norvegicus
Westphal, K.; Stangl, V.; Faehling, M.; Dreger, H.; Weller, A.; Baumann, G.; Stangl, K.; Meiners, S.
Human-specific induction of glutathione peroxidase-3 by proteasome inhibition in cardiovascular cells
Free Radic. Biol. Med.
47
1652-1660
2009
no activity in Bos taurus, Homo sapiens (P22352), Homo sapiens
Franco, J.L.; Posser, T.; Dunkley, P.R.; Dickson, P.W.; Mattos, J.J.; Martins, R.; Bainy, A.C.; Marques, M.R.; Dafre, A.L.; Farina, M.
Methylmercury neurotoxicity is associated with inhibition of the antioxidant enzyme glutathione peroxidase
Free Radic. Biol. Med.
47
449-457
2009
Homo sapiens, Mus musculus
Guan, T.; Song, J.; Wang, Y.; Guo, L.; Yuan, L.; Zhao, Y.; Gao, Y.; Lin, L.; Wang, Y.; Wei, J.
Expression and characterization of recombinant bifunctional enzymes with glutathione peroxidase and superoxide dismutase activities
Free Radic. Biol. Med.
110
188-195
2017
Homo sapiens (P07203), Homo sapiens
Guo, X.; Song, J.; Guan, T.; Wang, S.; Wang, Y.; Meng, Y.; Guo, J.; Li, T.; Ma, C.; Wei, J.
Characterization of recombinant human gastrointestinal glutathione peroxidase mutant produced in Escherichia coli
Free Radic. Res.
49
228-235
2015
Homo sapiens (P18283), Homo sapiens
Guo, X.; Yu, Y.; Liu, X.; Zhang, Y.; Guan, T.; Xie, G.; Wei, J.
Heterologous expression and characterization of human cellular glutathione peroxidase mutants
IUBMB Life
66
212-219
2014
Homo sapiens (P07203)
-
Song, J.; Yu, Y.; Xing, R.; Guo, X.; Liu, D.; Wei, J.; Song, H.
Unglycosylated recombinant human glutathione peroxidase 3 mutant from Escherichia coli is active as a monomer
Sci. Rep.
4
6698
2014
Homo sapiens (P22352), Homo sapiens
Lee, W.; Chen, Y.; Chu, Y.; Chien, D.
Comparison of glutathione peroxidase-3 protein expression and enzyme bioactivity in normal subjects and patients with sepsis
Clin. Chim. Acta
489
177-182
2019
Homo sapiens (P22352), Homo sapiens
Ramadhani, D.; Suvifan, V.; Purnami, S.; Rahajeng, N.; Lusiyanti, Y.; Wanandi, S.; Wibowo, H.; Miura, T.; Syaifudin, M.
Superoxide dismutase and glutathione peroxidase activities in a population exposed to high indoor radon concentration a preliminary report
Free Radic. Res.
55
1094-1103
2022
Homo sapiens
