6.5.1.8: 3'-phosphate/5'-hydroxy nucleic acid ligase

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For detailed information about 3'-phosphate/5'-hydroxy nucleic acid ligase, go to the full flat file.

Reaction

Synonyms

3'-P RNL, MXAN_0280, MXAN_4982, RNA-splicing ligase, rtcB, RtcB RNA ligase, Rtcb-1, RtcB1, Trl1, tRNA splicing ligase, tRNA-splicing ligase

ECTree

     6 Ligases

         6.5 Forming phosphoric-ester bonds

             6.5.1 Ligases that form phosphoric-ester bonds (only sub-subclass identified to date)

                6.5.1.8 3'-phosphate/5'-hydroxy nucleic acid ligase

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Results	in table
2	Activating Compound
1709	AA Sequence
12	Cloned(Commentary)
6	Cofactor
3	Crystallization (Commentary)
3	Disease/ Diagnostics
2	Expression
24	General Information
2	Localization
16	Metals/Ions
6	Molecular Weight [Da]
14	Natural Substrates/ Products (Substrates)
44	Organism
1	Pathway
15	PDB ID
45	Protein Variants
6	Purification (Commentary)
10	Reaction
36	Reference
3	Source Tissue
84	Substrates and Products (Substrate)
16	Subunits
36	Synonyms
1	Systematic Name
5	Turnover Number [1/s]

Expression

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Expression on EC 6.5.1.8 - 3'-phosphate/5'-hydroxy nucleic acid ligase

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EXPRESSION

ORGANISM

UNIPROT

LITERATURE

RtcB mRNA is processed by endoribonuclease MazF and selectively translated during stress

Escherichia coli

-

741078

the enzyme is enriched at axon termini after nerve injury

Caenorhabditis elegans

-

749175