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6.5.1.8: 3'-phosphate/5'-hydroxy nucleic acid ligase

This is an abbreviated version!
For detailed information about 3'-phosphate/5'-hydroxy nucleic acid ligase, go to the full flat file.

Word Map on EC 6.5.1.8

Reaction

(ribonucleotide)n-2',3'-cyclophosphate
+
5'-hydroxy-(ribonucleotide)m
+
GTP
+
H2O
=
(ribonucleotide)n+m
+
GMP
+
diphosphate

Synonyms

3'-P RNL, MXAN_0280, MXAN_4982, RNA-splicing ligase, rtcB, RtcB RNA ligase, Rtcb-1, RtcB1, Trl1, tRNA splicing ligase, tRNA-splicing ligase

ECTree

     6 Ligases
         6.5 Forming phosphoric-ester bonds
             6.5.1 Ligases that form phosphoric-ester bonds (only sub-subclass identified to date)
                6.5.1.8 3'-phosphate/5'-hydroxy nucleic acid ligase

Natural Substrates Products

Natural Substrates Products on EC 6.5.1.8 - 3'-phosphate/5'-hydroxy nucleic acid ligase

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NATURAL SUBSTRATE
NATURAL PRODUCT
REACTION DIAGRAM
ORGANISM
UNIPROT
COMMENTARY
(Substrate) hide
LITERATURE
(Substrate)
COMMENTARY
(Product) hide
LITERATURE
(Product)
REVERSIBILITY
r=reversible
ir=irreversible
?=not specified
(ribonucleotide)n-2',3'-cyclophosphate + 5'-hydroxy-(ribonucleotide)m + GTP + H2O
(ribonucleotide)n+m + GMP + diphosphate
show the reaction diagram
(ribonucleotide)n-3'-phosphate + 5'-hydroxy-(ribonucleotide)m + GTP
(ribonucleotide)n+m + GMP + diphosphate
show the reaction diagram